Package: SPIA
Version: 2.64.0
Date: 2025-1-20
Title: Signaling Pathway Impact Analysis (SPIA) using combined evidence
        of pathway over-representation and unusual signaling
        perturbations
Author: Adi Laurentiu Tarca <atarca@med.wayne.edu>, Purvesh Kathri
        <purvesh@cs.wayne.edu> and Sorin Draghici <sorin@wayne.edu>
Depends: R (>= 2.14.0), graphics, KEGGgraph
Suggests: graph, Rgraphviz, hgu133plus2.db
Maintainer: Adi Laurentiu Tarca <atarca@med.wayne.edu>
Description: This package implements the Signaling Pathway Impact
        Analysis (SPIA) which uses the information form a list of
        differentially expressed genes and their log fold changes
        together with signaling pathways topology, in order to identify
        the pathways most relevant to the condition under the study.
License: file LICENSE
License_restricts_use: yes
URL: http://bioinformatics.oxfordjournals.org/cgi/reprint/btn577v1
Collate: spia.R plotP.R combfunc.R getP2.R makeSPIAdata.R
Imports: graphics
LazyLoad: yes
Packaged: 2026-04-29 16:30:49 UTC; root
biocViews: Microarray, GraphAndNetwork
Config/pak/sysreqs: make libxml2-dev zlib1g-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2026-04-28 12:33:42 UTC
RemoteUrl: https://github.com/bioc/SPIA
RemoteRef: RELEASE_3_23
RemoteSha: 07118ad4190a5f6e61ba2d167cff3ca3ece37f74
NeedsCompilation: no
Built: R 4.6.0; ; 2026-04-29 16:41:28 UTC; unix
