REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION%REACTOME%R-HSA-2565942.1	Regulation of PLK1 Activity at G2 M Transition	CSNK1E	DYNLL1	TUBG1	CKAP5	TUBA4A	HAUS2	HAUS1	AKAP9	CEP63	MAPRE1	AJUBA	SFI1	UBA52	OPTN	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	CUL1	AURKA	CCNB2	CCNB1	UBB	HAUS8	HAUS7	PRKAR2B	UBC	CEP70	CEP72	CEP192	RPS27A	PCNT	CEP76	CLASP1	CEP78	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	CEP57	YWHAE	CETN2	CEP164	CCP110	PPP1CB	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	BTRC	NINL	CEP290	YWHAG	RAB8A	CDK5RAP2	SKP1	OFD1	HSP90AA1	BORA	PPP1R12A	CEP135	FBXW11	TUBB	CEP131	HAUS4	HAUS3	CSNK1D	HAUS6	HAUS5	
DEFECTIVE MAOA CAUSES BRUNNER SYNDROME (BRUNS)%REACTOME%R-HSA-5579012.1	Defective MAOA causes Brunner syndrome (BRUNS)	MAOA	
GLYCEROPHOSPHOLIPID BIOSYNTHESIS%REACTOME%R-HSA-1483206.4	Glycerophospholipid biosynthesis	PCYT1B	PCYT1A	PLA2G4D	PLA2G4B	PLA2G4C	PLA2G4A	GPCPD1	HADHB	HADHA	PITPNM1	PITPNM3	PITPNM2	MGLL	AGPAT5	AGPAT6	AGPAT9	PLA2G1B	AGPAT1	AGPAT2	AGPAT3	AGPAT4	AWAT2	GPAT2	CEPT1	CDIPT	PLA2G2F	BCHE	PLA2G2D	PLA2G2E	PNPLA8	AGK	MBOAT7	PLA2G2A	DDHD2	MBOAT1	MBOAT2	DDHD1	ETNPPL	GPAM	LPCAT4	ETNK2	LPCAT3	ETNK1	LPCAT2	PNPLA3	CHPT1	GPD1L	LPIN1	LPIN2	LPIN3	PNPLA2	LPGAT1	CPNE7	PITPNB	CPNE6	LCLAT1	PLB1	LIPI	LIPH	CPNE1	CPNE3	MFSD2A	DGAT2	PCYT2	DGAT1	CSNK2A1	STARD7	HRASLS2	CSNK2A2	PISD	PLA2G15	PLA2G16	GNPAT	PHOSPHO1	GPD2	PLA2G10	GPD1	CSNK2B	PLBD1	HRASLS5	PLA2R1	PLA1A	CDS1	ABHD4	ABHD3	CHAT	PLA2G3	PLD4	PLA2G5	PLD6	PLA2G6	PLD1	PLD3	PLD2	PGS1	PTDSS2	PTDSS1	PTPMT1	OSBPL8	TMEM86B	CHKB	OSBPL5	CHKA	RARRES3	STARD10	EPT1	DGAT2L6	CRLS1	PEMT	ALPI	CDS2	SLC44A5	ACHE	SLC44A3	SLC44A4	SLC44A1	SLC44A2	LPCAT1	PCTP	TAZ	OSBPL10	ACP6	FAM73A	FAM73B	PLA2G12A	PLA2G4F	
MITOTIC PROPHASE%REACTOME DATABASE ID RELEASE 74%68875	Mitotic Prophase	SETD8	NUMA1	NCAPG2	LMNB1	HIST2H2AC	H2AFJ	NUP62	ENSA	EMD	NDC1	SEC13	NUP133	H2AFZ	H2AFX	H2AFV	MASTL	HIST2H2BE	GORASP2	HIST4H4	NUP50	CNEP1R1	GORASP1	CCNB2	NUP54	CCNB1	MCPH1	HIST1H2BN	HIST1H2BM	RAB1A	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	RAB1B	USO1	HIST1H2BK	PPP2CA	HIST2H4A	PPP2CB	HIST2H4B	MAPK1	NUP43	RAE1	RANBP2	PLK1	PPP2R2D	HIST3H3	NUP35	NCAPD3	NUPL2	CDK1	LPIN1	NUP37	LPIN2	LPIN3	RB1	NUP107	NUP188	SMC4	SMC2	GOLGA2	PPP2R1B	HIST1H2AE	HIST1H2AD	BANF1	HIST3H2BB	HIST1H2AC	HIST1H2AB	RAB2A	NUP214	NUP210	PRKCB	HIST1H2AJ	VRK1	PRKCA	LEMD3	LEMD2	NUP93	CTDNEP1	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	BLZF1	HIST1H2BD	HIST1H2BC	NUP205	POM121	H2AFB1	SET	HIST1H3J	AAAS	ARPP19	NUP160	HIST1H3A	NUP85	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	HIST1H3I	HIST1H3B	PPP2R1A	HIST1H3C	HIST1H3D	HIST1H3E	NEK9	NUP155	H3F3B	HIST1H4K	HIST1H4L	NEK6	NCAPH2	NEK7	H3F3A	NUP153	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
VPR-MEDIATED INDUCTION OF APOPTOSIS BY MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION%REACTOME%R-HSA-180897.2	Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization	SLC25A5	SLC25A4	SLC25A6	
ACTIVATION OF NF-KAPPAB IN B CELLS%REACTOME%R-HSA-1169091.1	Activation of NF-kappaB in B cells	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	CARD11	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	BCL10	PSMB10	MALT1	PSMA7	CUL1	RELA	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	REL	NFKBIE	NFKBIB	PRKCB	BTRC	PSMD8	SKP1	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	FBXW11	PSMD2	PSMD3	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	
TRANSPORT OF FATTY ACIDS%REACTOME DATABASE ID RELEASE 74%804914	Transport of fatty acids	LCN9	SLC27A1	LCN15	LCN12	LCN1	SLC27A6	APOD	SLC27A4	
CD28 DEPENDENT PI3K AKT SIGNALING%REACTOME DATABASE ID RELEASE 74%389357	CD28 dependent PI3K Akt signaling	CD28	THEM4	AKT1	TRIB3	MAP3K8	FYN	RICTOR	MAP3K14	PRR5	CD86	PDPK1	MAPKAP1	CD80	PIK3R3	PIK3R2	PIK3R1	MTOR	PIK3CA	LCK	AKT2	AKT3	MLST8	
UBIQUITIN-DEPENDENT DEGRADATION OF CYCLIN D%REACTOME DATABASE ID RELEASE 74%75815	Ubiquitin-dependent degradation of Cyclin D	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	GSK3B	CCND1	CDK4	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
DEGRADATION OF THE EXTRACELLULAR MATRIX%REACTOME%R-HSA-1474228.4	Degradation of the extracellular matrix	PRSS1	COL16A1	COL12A1	CAPN15	CAPN8	CAPN9	CAPN6	CAPNS1	CAPN7	CDH1	CAPNS2	BSG	CAPN5	CAPN2	CAPN3	CAPN1	PRSS2	CAST	PHYKPL	CTRB2	COL23A1	CTRB1	ADAM10	HSPG2	BCAN	ADAM17	ADAM15	OPTC	ADAM9	ADAM8	COL17A1	COL13A1	HTRA1	PSEN1	KLK2	NID1	KLK7	ADAMTS16	SCUBE3	NCSTN	SCUBE1	ADAMTS18	A2M	ELANE	BMP1	COL9A1	COL9A3	COL9A2	COL18A1	COL14A1	LAMC2	LAMC1	CTSV	CTSS	MMP20	ADAMTS4	ADAMTS5	MMP25	MMP24	ADAMTS1	CTSL	CASP3	CTSK	TIMP2	CTSG	TIMP1	TPSAB1	ADAMTS8	CTSD	ADAMTS9	CTSB	MMP7	MMP1	COL25A1	MMP2	MMP3	MMP8	MMP9	MMP10	DCN	MMP12	MMP11	MMP14	MMP13	MMP16	MMP15	MMP17	MMP19	CD44	LAMA5	COL15A1	TMPRSS6	LAMA3	PLG	FURIN	COL19A1	SPOCK3	SPP1	COL26A1	LAMB3	CMA1	LAMB1	CAPN13	CAPN14	CAPN11	CAPN12	CAPN10	TLL2	TLL1	KLKB1	
DEFECTIVE SLC1A3 CAUSES EPISODIC ATAXIA 6 (EA6)%REACTOME DATABASE ID RELEASE 74%5619062	Defective SLC1A3 causes episodic ataxia 6 (EA6)	SLC1A3	
TRANSCRIPTION OF SARS-COV-1 SGRNAS%REACTOME%R-HSA-9682708.2	Transcription of SARS-CoV-1 sgRNAs	
ABC-FAMILY PROTEINS MEDIATED TRANSPORT%REACTOME DATABASE ID RELEASE 74%382556	ABC-family proteins mediated transport	ABCA12	ABCG8	ABCG5	ABCA10	ABCG4	CFTR	ABCG1	VCP	UBA52	ABCB1	ABCB6	ABCB7	ABCB4	ABCB5	SEL1L	ABCB8	ABCB9	ABCA2	ABCA5	ABCA6	ABCA3	UBB	ABCA4	ABCA9	ERLIN1	ABCA7	UBC	ERLIN2	ABCA8	EIF2S2	EIF2S1	EIF2S3	RPS27A	RNF185	ABCD2	ABCD3	ABCC10	ABCC11	ABCD1	ABCC3	ABCC4	ABCC1	ABCC2	ABCC5	ABCC6	APOA1	ABCC9	PEX3	DERL3	DERL1	DERL2	RNF5	ERLEC1	OS9	ABCF1	PEX19	KCNJ11	ABCB10	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	
PIWI-INTERACTING RNA (PIRNA) BIOGENESIS%REACTOME DATABASE ID RELEASE 74%5601884	PIWI-interacting RNA (piRNA) biogenesis	PIWIL2	TDRKH	PIWIL1	PIWIL4	DDX4	HENMT1	PLD6	POLR2A	POLR2B	POLR2C	ASZ1	POLR2D	MAEL	POLR2E	POLR2F	MOV10L1	POLR2G	POLR2H	POLR2I	POLR2J	MYBL1	POLR2K	POLR2L	TDRD9	TDRD6	TDRD1	TDRD12	FKBP6	HSP90AA1	
REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU-RICH ELEMENTS%REACTOME%R-HSA-450531.4	Regulation of mRNA stability by proteins that bind AU-rich elements	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	YWHAB	PSMB10	HSPB1	ELAVL1	PSMA7	XPO1	KHSRP	PSMA8	TNPO1	PSMB6	DIS3	PSMB7	PRKCD	PSMB4	UBB	YWHAZ	PSMB5	XRN1	PSMB2	MAPKAPK2	PSMB3	PABPC1	UBC	PSMB1	DCP2	PSMF1	ANP32A	SHFM1	PARN	PSMB8	ZFP36L1	RPS27A	EXOSC7	PSMB9	EXOSC6	EXOSC5	PSMC5	EXOSC4	PSMC6	EXOSC9	PSMC3	EXOSC8	PSMC4	EXOSC3	PSMC1	EXOSC2	PSMC2	EXOSC1	HSPA8	TNFSF13	MAPK14	MAPK11	DCP1A	EIF4G1	NUP214	PRKCA	SET	AKT1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
HEDGEHOG 'OFF' STATE%REACTOME%R-HSA-5610787.1	Hedgehog 'off' state	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY5	CSNK1A1	WDR19	ITCH	UBA52	CUL1	UBB	PRKAR2B	UBC	RPS27A	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	IFT172	PRKACG	PRKACB	DYNC2H1	RPGRIP1L	RBX1	IFT88	ADCY9	PRKAR1B	SMO	PRKAR1A	GPR161	INTU	KIF3A	PRKACA	PRKAR2A	GSK3B	BTRC	TTC21B	PTCH1	IFT122	FUZ	ADCY10	GNAS	SKP1	MKS1	GLI1	OFD1	GLI3	GLI2	IFT52	SUFU	IFT57	IFT140	KIF7	WDR35	NUMB	ADCY4	TULP3	ADCY3	
CITRIC ACID CYCLE (TCA CYCLE)%REACTOME DATABASE ID RELEASE 74%71403	Citric acid cycle (TCA cycle)	FAHD1	MDH2	IDH3G	IDH2	DLST	SDHC	SDHD	SDHA	SDHB	CS	SUCLA2	NNT	IDH3B	OGDH	SUCLG2	SUCLG1	ME3	ME2	ACO2	DLD	IDH3A	FH	
INTERLEUKIN-33 SIGNALING%REACTOME%R-HSA-9014843.2	Interleukin-33 signaling	IL1RL1	IL33	
INTRA-GOLGI AND RETROGRADE GOLGI-TO-ER TRAFFIC%REACTOME DATABASE ID RELEASE 74%6811442	Intra-Golgi and retrograde Golgi-to-ER traffic	RINT1	DYNC1LI1	DYNLL1	RAB30	DYNC1LI2	RAB36	KIF16B	PLA2G4A	ZW10	KDELR2	KIF20A	KDELR3	KIF20B	COPB2	COPA	TMED10	COPB1	PAFAH1B1	RHOBTB3	ARL1	DYNC1I2	KLC1	DCTN2	TGOLN2	KLC4	DCTN3	AGPAT3	KLC3	KLC2	KIF3B	RACGAP1	MAN2A2	MAN2A1	VTI1A	RAB1A	KIF3C	RAB6A	RAB6B	SURF4	RAB39A	RAB1B	M6PR	IGF2R	KIF18A	KIF18B	ALPP	KIF4B	KIF4A	DYNC1H1	COPE	ARF3	ARF4	ARF1	KIF11	BICD1	USE1	RABEPK	BICD2	KIF15	KIF19	CAPZB	MAN1A2	KIF13B	TMED3	KIF1C	TMED2	MAN1A1	KIF1B	KIF1A	TMED7	SNAP29	TMED9	NAA30	KIF25	COPZ2	KIF23	KIF22	ARFGAP3	KIF6	DYNLL2	BET1L	ARFGAP1	KIF27	COPZ1	RAB33B	ARFGAP2	KIF9	KIFC2	KIF2A	KIFC1	PLIN3	NAA35	KIF2C	NAA38	KIF2B	SEC22B	VAMP4	PAFAH1B3	ARF5	PAFAH1B2	VAMP3	DCTN6	NAPA	DCTN5	NAPB	NBAS	TMF1	STX16	DCTN1	DCTN4	GOSR2	STX18	GOSR1	NAPG	STX10	CYTH3	CYTH2	ARFRP1	CYTH4	CUX1	VPS51	VPS53	VPS52	BNIP1	MAN1C1	STX6	STX5	VPS54	YKT6	CYTH1	DYNC1I1	RIC1	GALNT2	GALNT1	GBF1	ARCN1	RGP1	CENPE	CAPZA3	KIF26A	CAPZA1	KIF26B	CAPZA2	RAB18	RAB3GAP2	TRIP11	RAB9A	COPG2	VPS45	COPG1	ACTR10	RAB3GAP1	RAB9B	PLA2G6	ACTR1A	USP6NL	SCOC	SYS1	KDELR1	GOLIM4	GCC2	KIF3A	GCC1	RAB43	RAB41	GOLGA4	GOLGA5	KIF5B	KIF5A	GOLGA1	ARFIP2	KIF21A	KIF21B	KIFAP3	NSF	COG8	COG7	COG6	COG5	COG4	COG3	COG2	COG1	
MRNA DECAY BY 5' TO 3' EXORIBONUCLEASE%REACTOME DATABASE ID RELEASE 74%430039	mRNA decay by 5' to 3' exoribonuclease	LSM3	EDC3	LSM2	EDC4	LSM7	LSM6	DCP1B	DCP1A	XRN1	DDX6	LSM1	LSM5	DCP2	LSM4	PATL1	
CA2+ PATHWAY%REACTOME DATABASE ID RELEASE 74%4086398	Ca2+ pathway	FZD2	FZD5	PDE6G	FZD4	FZD6	NFATC1	GNG12	GNG11	GNG13	GNAO1	TNRC6C	MOV10	AGO3	AGO4	GNB2	AGO1	GNB1	AGO2	GNB4	GNB3	CTNNB1	GNB5	TNRC6A	TNRC6B	PRKCA	GNGT1	PPP3CA	PPP3CB	GNGT2	GNAT2	PRKG2	PRKG1	WNT5A	PLCB3	PLCB1	PLCB2	CAMK2A	LEF1	TCF7	ITPR1	ITPR2	ITPR3	NLK	GNG3	GNG10	PPP3R1	GNG2	WNT11	GNG5	GNG4	GNG7	GNG8	PDE6B	PDE6A	MAP3K7	TCF7L2	FZD3	TCF7L1	
CS DS DEGRADATION%REACTOME%R-HSA-2024101.2	CS DS degradation	IDUA	HEXB	NCAN	HEXA	BGN	VCAN	HYAL1	HYAL3	DCN	IDS	CSPG5	CSPG4	ARSB	BCAN	
SEMA4D INDUCED CELL MIGRATION AND GROWTH-CONE COLLAPSE%REACTOME DATABASE ID RELEASE 74%416572	Sema4D induced cell migration and growth-cone collapse	ARHGEF11	ARHGEF12	ROCK1	SEMA4D	ROCK2	LIMK2	LIMK1	RHOC	RHOA	MYL12B	RHOB	RND1	MYL6	ERBB2	MYH9	MYH14	MYH11	PLXNB1	MYH10	MYL9	
ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA%REACTOME DATABASE ID RELEASE 74%111447	Activation of BAD and translocation to mitochondria	PPP3CC	YWHAQ	BCL2	AKT1	SFN	BID	YWHAH	YWHAG	YWHAB	PPP3R1	YWHAZ	AKT2	AKT3	YWHAE	BAD	
SERINE BIOSYNTHESIS%REACTOME%R-HSA-977347.4	Serine biosynthesis	PSAT1	SERINC1	PHGDH	SERINC3	SERINC2	PSPH	SERINC5	SERINC4	SRR	
RSK ACTIVATION%REACTOME DATABASE ID RELEASE 74%444257	RSK activation	RPS6KA1	MAPK3	PDPK1	MAPK1	RPS6KA3	RPS6KA6	RPS6KA2	
VITAMIN E%REACTOME DATABASE ID RELEASE 74%8877627	Vitamin E	TTPA	
CONSTITUTIVE SIGNALING BY EGFRVIII%REACTOME DATABASE ID RELEASE 74%5637810	Constitutive Signaling by EGFRvIII	SHC1	EGF	GAB1	CBL	EGFR	NRAS	HSP90AA1	CDC37	PLCG1	SOS1	HRAS	PIK3R1	PIK3CA	
VEGF BINDS TO VEGFR LEADING TO RECEPTOR DIMERIZATION%REACTOME%R-HSA-195399.1	VEGF binds to VEGFR leading to receptor dimerization	FIGF	FLT1	FLT4	VEGFB	KDR	VEGFC	PGF	VEGFA	
CYTOSOLIC TRNA AMINOACYLATION%REACTOME%R-HSA-379716.1	Cytosolic tRNA aminoacylation	YARS	CARS	DARS	WARS	VARS	TARS	SARS	EPRS	NARS	AIMP1	AIMP2	QARS	KARS	PPA1	LARS	MARS	RARS	GARS	HARS	IARS	EEF1E1	FARSA	FARSB	AARS	
CAP-DEPENDENT TRANSLATION INITIATION%REACTOME DATABASE ID RELEASE 74%72737	Cap-dependent Translation Initiation	UBA52	EIF2S2	EIF2S1	EIF2S3	RPS27A	RPL4	EIF4A2	EIF4A1	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	EIF1AX	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	EIF4EBP1	EIF2B5	RPL39L	EIF2B4	EIF2B3	RPL41	EIF2B2	RPL3L	RPS26	RPS25	RPS28	EIF5	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	EIF2B1	EIF5B	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	PABPC1	RPS27L	RPS15A	RPL14	RPS3	EIF4H	RPL13	RPL15	RPS2	RPL18	RPL17	EIF4E	EIF4B	RPL19	RPL35A	RPL23A	EIF3M	EIF3K	EIF3L	EIF3I	EIF4G1	EIF3J	EIF3G	EIF3H	EIF3E	RPL22L1	EIF3F	FAU	EIF3C	EIF3D	EIF3A	RPL26L1	EIF3B	
SIGNALING BY NTRK3 (TRKC)%REACTOME DATABASE ID RELEASE 74%9034015	Signaling by NTRK3 (TRKC)	PTPRS	IRS1	SRC	NTRK3	PTPRO	NTF3	BAX	NELFB	NRAS	PLCG1	SOS1	HRAS	PIK3R1	PIK3CA	
TGFBR1 KD MUTANTS IN CANCER%REACTOME DATABASE ID RELEASE 74%3656532	TGFBR1 KD Mutants in Cancer	SMAD2	SMAD3	TGFB1	TGFBR1	TGFBR2	
SIGNALING BY NOTCH2%REACTOME DATABASE ID RELEASE 74%1980145	Signaling by NOTCH2	MIB2	GZMB	MIB1	FCER2	NCSTN	CREB1	NEURL1	CNTN1	MAML3	MAMLD1	UBA52	UBB	UBC	RPS27A	NOTCH2	MAML2	MAML1	PSEN2	RBPJ	ADAM10	DLL1	DLL4	APH1A	NEURL1B	APH1B	MDK	EP300	HES1	HES5	JAG2	PSEN1	PSENEN	JAG1	
DEFECTIVE GALNT12 CAUSES COLORECTAL CANCER 1 (CRCS1)%REACTOME DATABASE ID RELEASE 74%5083636	Defective GALNT12 causes colorectal cancer 1 (CRCS1)	MUC3A	MUC5AC	MUC1	MUC7	MUC12	MUC13	MUC15	MUC20	MUC4	MUC21	MUC6	GALNT12	MUCL1	MUC17	MUC5B	
TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRON-CONTAINING TRANSCRIPT%REACTOME%R-HSA-159236.3	Transport of Mature mRNA derived from an Intron-Containing Transcript	SRSF11	CHTOP	UPF3B	MAGOHB	NXF2B	RNPS1	NUP62	NDC1	SEC13	NUP133	NUP50	NUP54	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	NUP107	NUP188	NUP214	NUP210	NUP93	NUP205	POM121	NXT1	EIF4A3	AAAS	CASC3	GLE1	NUP160	MAGOH	NCBP1	NUP85	NCBP2	TPR	THOC1	THOC3	THOC2	NUP88	THOC5	THOC7	CDC40	SRRM1	THOC6	DDX39A	DDX39B	SARNP	NUP155	ZC3H11A	SRSF2	SRSF3	SRSF4	SRSF5	SRSF6	SRSF7	SLU7	NUP153	SRSF9	FYTTD1	LUZP4	RBM8A	POLDIP3	SRSF1	U2AF1	U2AF1L4	NXF1	NXF2	U2AF2	DHX38	
INFLUENZA INFECTION%REACTOME DATABASE ID RELEASE 74%168255	Influenza Infection	NUP62	NDC1	SEC13	NUP133	UBA52	NUP50	NUP54	RPS27A	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	SLC25A6	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	POLR2A	RPS16	POLR2B	RPL18A	POLR2C	RPS19	RPL36AL	POLR2D	RPS18	RPL36	POLR2E	RPL35	POLR2F	RPL38	RPL37	POLR2G	RPS11	POLR2H	RPL39	POLR2I	RPS10	POLR2J	RPS13	RPS12	POLR2K	RPS9	POLR2L	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	XPO1	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	IPO5	RPS27L	KPNA7	RPS15A	KPNA4	RPL14	KPNA5	RPS3	KPNA2	KPNA3	RPL13	KPNA1	RPL15	GTF2F1	RPS2	GTF2F2	RPL18	KPNB1	RPL17	CPSF4	EIF2AK2	ISG15	RPL19	CALR	RPL35A	GRSF1	RPL23A	CLTC	CLTA	PARP1	DNAJC3	CANX	PABPN1	RAN	NUP107	RPL22L1	NUP188	FAU	RPL26L1	NUP214	NUP210	NUP93	TGFB1	NUP205	POM121	AAAS	NUP160	NUP85	TPR	NUP88	NUP155	NUP153	HSP90AA1	
COPI-MEDIATED ANTEROGRADE TRANSPORT%REACTOME DATABASE ID RELEASE 74%6807878	COPI-mediated anterograde transport	CAPZA3	DYNLL1	DYNC1LI1	CAPZA1	DYNC1LI2	CAPZA2	KDELR2	KDELR3	COPG2	COPB2	COPG1	COPA	ACTR10	TMED10	COPB1	DYNC1I2	DCTN2	DCTN3	GORASP1	RAB1A	RAB1B	USO1	DYNC1H1	COPE	ARF3	ARF4	ARF1	CAPZB	TMED3	GOLGA2	TMED2	TMED7	TMED9	COPZ2	SPTAN1	ARFGAP3	ANK2	ANK3	DYNLL2	ANK1	BET1L	SPTB	ARFGAP1	SPTBN4	COPZ1	SPTBN5	INS	ARFGAP2	SPTA1	CD59	CD55	SPTBN1	SPTBN2	TMEM115	GOLGB1	FOLR1	BET1	ARF5	DCTN6	NAPA	DCTN5	NAPB	DCTN1	DCTN4	ACTR1A	GOSR2	GOSR1	NAPG	KDELR1	STX5	YKT6	NSF	COG8	DYNC1I1	COG7	COG6	COG5	COG4	GBF1	COG3	ARCN1	COG2	COG1	
SMALL INTERFERING RNA (SIRNA) BIOGENESIS%REACTOME%R-HSA-426486.4	Small interfering RNA (siRNA) biogenesis	AGO2	TSNAX	PRKRA	DICER1	AGO3	TARBP2	AGO4	TSN	AGO1	
SWITCHING OF ORIGINS TO A POST-REPLICATIVE STATE%REACTOME%R-HSA-69052.3	Switching of origins to a post-replicative state	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	MCM7	PSME3	MCM8	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	SKP2	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	CCNE2	CCNE1	PSMB10	MCM3	MCM4	PSMA7	ANAPC4	CUL1	MCM5	PSMA8	ANAPC5	PSMB6	MCM6	PSMB7	ANAPC1	PSMB4	UBB	MCM2	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	ORC5	PSMB8	ORC4	RPS27A	FZR1	PSMB9	ORC6	ORC1	PSMC5	ORC3	PSMC6	ORC2	PSMC3	CDT1	PSMC4	UBE2C	PSMC1	CDC6	PSMC2	UBE2S	CDC16	CDK2	RBX1	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
METALLOTHIONEINS BIND METALS%REACTOME DATABASE ID RELEASE 74%5661231	Metallothioneins bind metals	MT3	MT1E	MT2A	MT1A	MT1M	MT1F	MT1G	MT1X	MT1H	MT1B	MT4	
FCERI MEDIATED NF-KB ACTIVATION%REACTOME%R-HSA-2871837.2	FCERI mediated NF-kB activation	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	UBE2D2	PSME3	IGKV2-28	PSME4	UBE2D1	IGKV1-12	PSME1	IGKV3D-20	PSME2	CDC34	CARD11	IGKV2D-28	PSMD10	TRAF6	PSMB11	IGKV4-1	UBA52	PSMD12	IGHE	PSMD11	PRKCQ	PSMD14	UBE2V1	PSMD13	IGKV2D-30	BCL10	RASGRP2	PSMB10	RASGRP1	MALT1	PSMA7	RASGRP4	CUL1	RELA	IGKV3-11	PSMA8	LYN	PSMB6	IGKV5-2	PSMB7	UBE2N	PSMB4	UBB	TAB3	PSMB5	TAB2	PSMB2	TAB1	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	PDPK1	BTRC	PSMD8	SKP1	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	FBXW11	PSMD2	PSMD3	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	
NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION%REACTOME%R-HSA-164940.1	Nef mediated downregulation of MHC class I complex cell surface expression	AP1G1	PACS1	AP1B1	AP1S2	AP1S1	AP1S3	HLA-A	B2M	AP1M2	AP1M1	
LIGAND-DEPENDENT CASPASE ACTIVATION%REACTOME%R-HSA-140534.5	Ligand-dependent caspase activation	LY96	TNFRSF10B	TRAF2	TNFRSF10A	FASLG	TICAM1	CASP8	TNFSF10	FAS	RIPK1	CD14	FADD	TLR4	TICAM2	TRADD	
FIBRONECTIN MATRIX FORMATION%REACTOME DATABASE ID RELEASE 74%1566977	Fibronectin matrix formation	ITGB1	CEACAM1	CEACAM6	FN1	CEACAM8	ITGA5	
DEFECTIVE MUT CAUSES METHYLMALONIC ACIDURIA MUT TYPE%REACTOME%R-HSA-3359478.1	Defective MUT causes methylmalonic aciduria mut type	MMAA	MUT	
ACTIVATION OF CA-PERMEABLE KAINATE RECEPTOR%REACTOME DATABASE ID RELEASE 74%451308	Activation of Ca-permeable Kainate Receptor	DLG1	DLG3	DLG4	GRIK5	GRIK3	GRIK4	GRIK1	GRIK2	NCALD	
CD209 (DC-SIGN) SIGNALING%REACTOME DATABASE ID RELEASE 74%5621575	CD209 (DC-SIGN) signaling	NFKB1	PAK3	RAF1	PAK2	FYN	PRKACA	NRAS	RELA	LYN	HRAS	CREBBP	ICAM2	EP300	ICAM3	RELB	PAK1	RPS6KA5	PRKACG	CD209	PRKACB	
TAT-MEDIATED HIV ELONGATION ARREST AND RECOVERY%REACTOME DATABASE ID RELEASE 74%167243	Tat-mediated HIV elongation arrest and recovery	NELFB	CTDP1	ELL	CCNT1	SUPT4H1	POLR2A	TCEB3	POLR2B	TCEB2	POLR2C	TCEB1	NELFA	POLR2D	NELFCD	TCEB3C	POLR2E	TCEB3CL	POLR2F	TCEB3B	NELFE	GTF2F1	POLR2G	SUPT16H	GTF2F2	POLR2H	SSRP1	POLR2I	SUPT5H	POLR2J	CDK9	TCEA1	POLR2K	TCEB3CL2	POLR2L	
MTOR SIGNALLING%REACTOME%R-HSA-165159.6	MTOR signalling	PRKAA1	PRKAA2	CAB39	CAB39L	PRKAG1	PRKAG2	PRKAG3	YWHAB	RPTOR	STK11	EEF2K	SLC38A9	PRKAB2	STRADA	STRADB	TSC2	TSC1	PRKAB1	MTOR	FKBP1A	PPM1A	AKT2	RRAGA	RRAGC	MLST8	RPS6KB1	RRAGB	RHEB	AKT1	AKT1S1	RRAGD	LAMTOR2	LAMTOR1	EIF4E	LAMTOR4	EIF4B	LAMTOR3	LAMTOR5	EIF4G1	RPS6	EIF4EBP1	
DEFECTIVE TPR MAY CONFER SUSCEPTIBILITY TOWARDS THYROID PAPILLARY CARCINOMA (TPC)%REACTOME%R-HSA-5619107.2	Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	AAAS	NUP160	NUP85	TPR	NUP88	NUP43	RAE1	RANBP2	GCKR	NUP155	GCK	NUP35	NUPL2	NUP37	NUP107	NUP153	NUP188	
RNA POLYMERASE III ABORTIVE AND RETRACTIVE INITIATION%REACTOME DATABASE ID RELEASE 74%749476	RNA Polymerase III Abortive And Retractive Initiation	GTF3C1	GTF3C2	GTF3C3	CRCP	GTF3C4	NFIX	GTF3C5	GTF3C6	SNAPC5	SNAPC1	SNAPC2	SNAPC3	SNAPC4	ZNF143	POU2F1	POLR2E	BRF2	POLR2F	TBP	SSB	BRF1	POLR2H	POLR3GL	GTF3A	POLR3A	POLR3B	POLR2K	NFIA	POLR2L	POLR3C	NFIB	POLR3D	NFIC	POLR3E	POLR1C	POLR3F	POLR3G	POLR3H	BDP1	POLR3K	
FORMATION OF FIBRIN CLOT (CLOTTING CASCADE)%REACTOME%R-HSA-140877.2	Formation of Fibrin Clot (Clotting Cascade)	A2M	KLKB1	SERPINE2	SERPINC1	PROS1	F13A1	PRCP	TFPI	KNG1	SERPINA5	THBD	C1QBP	PF4V1	CD177	FGB	FGA	F10	SERPIND1	VWF	GP1BB	F12	F11	F2R	FGG	GP1BA	F2	GP5	F3	F5	F7	GP9	PROCR	F8	F9	PROC	SERPING1	PRTN3	F13B	PF4	
GLYCOGEN BREAKDOWN (GLYCOGENOLYSIS)%REACTOME DATABASE ID RELEASE 74%70221	Glycogen breakdown (glycogenolysis)	PYGB	AGL	GAA	PHKB	PHKA1	PYGM	PYGL	PHKA2	PGM2L1	PHKG1	PHKG2	PGM2	GYG2	GYG1	
SIGNALING BY ERYTHROPOIETIN%REACTOME DATABASE ID RELEASE 74%9006335	Signaling by Erythropoietin	STAT5A	STAT5B	EPO	PIK3CD	IRS2	SHC1	PIK3CB	PIK3CG	GAB1	VAV1	EPOR	PIK3R5	CRKL	NRAS	RAPGEF1	LYN	PLCG2	PLCG1	JAK2	SOS1	HRAS	PIK3R1	PIK3CA	
DIMERIZATION OF PROCASPASE-8%REACTOME DATABASE ID RELEASE 74%69416	Dimerization of procaspase-8	TNFRSF10B	TRAF2	TNFRSF10A	FASLG	CASP8	TNFSF10	FAS	RIPK1	FADD	TRADD	
FLT3 SIGNALING%REACTOME DATABASE ID RELEASE 74%9607240	FLT3 Signaling	UBA52	UBB	UBC	RPS27A	PPP2CA	PPP2CB	MAPK1	STAT5A	STAT5B	IRS2	PIK3CB	JAK2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PRKCQ	PSMD14	PSMD13	YWHAB	PSMB10	RASGRP1	PSMA7	RASGRP4	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	IRS1	SRC	PDPK1	FN1	PIK3R2	PIK3R1	PIK3CA	AKT2	THEM4	RBX1	TRIB3	ARAF	WDR83	PRKG2	FYN	SYNGAP1	DLG1	GOLGA7	DLG3	ACTN2	DLG4	PAQR3	FLT3LG	FRS2	CAMK2A	FRS3	EREG	BTC	TLN1	PIK3R4	PDGFB	TGFA	IQGAP1	RCE1	RALGDS	BRAP	ICMT	BRAF	GRIN2B	PTK2	GRIN2D	PPP5C	ARTN	RGL3	RGL1	RGL2	RET	RAF1	AREG	PEA15	NEFL	JAK3	JAK1	DUSP4	DUSP5	LYPLA1	DUSP2	DUSP1	GFRA1	GAB2	DUSP8	GFRA3	IL17RD	DUSP9	GFRA2	DUSP6	DUSP7	GFRA4	CNKSR2	APBB1IP	HCK	CNKSR1	MRAS	LRRC7	KIT	TLR9	RAPGEF2	HBEGF	SHOC2	DAB2IP	RANBP9	USP17L2	GRIN1	EPGN	ZDHHC9	KBTBD7	KLB	CSF2	ITGA2B	PEBP1	IL5RA	FGF1	FGF2	FGF3	FGF4	PPP1CC	FGF6	FGF7	FNTA	FGF9	FNTB	NRTN	PDGFRB	PDGFRA	MAP2K1	MAP2K2	HGF	VCL	SHC2	SHC3	CUL3	ARL2	CSF2RB	RASAL1	PHB	RASAL2	RASAL3	CSF2RA	RASGRP3	RAP1B	RAP1A	FGF20	MARK3	FGF23	FGF22	PSPN	IL2	FGF16	ERBB2	IL3	IL5	DLG2	GDNF	PTPRA	FGF19	FGF18	NF1	FGFR4	MAP3K11	BCL2L1	FGF10	FLT3	ITGB3	RASGRF2	PDE3B	RASGRF1	ARRB1	LAMTOR2	ARRB2	DUSP16	SPRED3	LAMTOR3	SPRED2	SPRED1	DUSP10	RASGEF1A	PPP2R5E	KSR1	PPP2R5B	PPP2R5A	PPP2R5D	NRG1	PPP2R5C	KSR2	NRG2	RASA3	NRG3	RASA4	NRG4	RASA1	IL3RA	RASA2	PIK3C3	MET	CAMK2B	CAMK2D	ABHD17C	IL2RG	PDE6D	MAPK3	CSK	NCAM1	CAMK2G	ANGPT1	PTPN11	MAPK12	ABHD17B	ABHD17A	IL2RA	IL2RB	KRAS	TEK	SHC1	PTPN7	EGF	PTPN3	GAB1	EGFR	NRAS	SOS1	HRAS	PPP2R1B	SPTAN1	SPTB	SPTBN4	SPTBN5	SPTA1	SPTBN1	SPTBN2	PPP1CB	FGB	PPP2R1A	FGA	VWF	FGG	
THE RETINOID CYCLE IN CONES (DAYLIGHT VISION)%REACTOME DATABASE ID RELEASE 74%2187335	The retinoid cycle in cones (daylight vision)	AWAT2	OPN1SW	OPN1MW	OPN1LW	RBP3	OPN1MW2	DHRS3	RLBP1	
EUKARYOTIC TRANSLATION ELONGATION%REACTOME%R-HSA-156842.2	Eukaryotic Translation Elongation	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	UBA52	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	RPS27A	RPL13	RPL15	RPS2	RPL18	RPL17	EEF1B2	EEF1A1	EEF1G	RPL19	EEF1D	RPL35A	EEF1A2	RPL23A	EEF2	RPL22L1	FAU	RPL26L1	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	
INITIAL TRIGGERING OF COMPLEMENT%REACTOME DATABASE ID RELEASE 74%166663	Initial triggering of complement	FCN1	CFD	IGKV2-28	CRP	IGKV1-12	C1QB	IGKV3D-20	COLEC11	C1QA	IGKV2D-28	FCN2	COLEC10	IGKV4-1	FCN3	C1S	C1R	IGKV2D-30	C4B_2	C2	C3	C4B	IGHG4	IGKV3-11	C4A	IGHG1	IGKV5-2	IGHG2	MBL2	GZMM	MASP1	CFB	C1QC	
LOCALIZATION OF THE PINCH-ILK-PARVIN COMPLEX TO FOCAL ADHESIONS%REACTOME DATABASE ID RELEASE 74%446343	Localization of the PINCH-ILK-PARVIN complex to focal adhesions	PXN	ILK	ITGB1	
SMAD2 3 PHOSPHORYLATION MOTIF MUTANTS IN CANCER%REACTOME%R-HSA-3304356.2	SMAD2 3 Phosphorylation Motif Mutants in Cancer	SMAD2	SMAD3	TGFB1	TGFBR1	TGFBR2	
RESPIRATORY ELECTRON TRANSPORT%REACTOME DATABASE ID RELEASE 74%611105	Respiratory electron transport	SDHC	SDHD	SDHA	SDHB	MT-ND6	NDUFA13	MT-ND4	MT-ND5	NDUFA11	MT-CO1	NDUFA12	TACO1	NDUFA10	COX6A1	MT-ND2	MT-ND3	MT-ND1	COX6B1	COX7A2L	SCO1	SCO2	UQCRC1	MT-CO2	UQCRC2	MT-CO3	TMEM126B	COX19	COX16	NDUFB10	UQCRB	NDUFB11	COX18	UQCRH	COX11	COX14	NDUFV3	CYC1	NDUFV2	NDUFV1	TRAP1	SURF1	NDUFAF6	NDUFAF7	UQCRQ	NDUFAF4	NDUFAF5	NDUFAF2	CYCS	NDUFAF3	NDUFAF1	MT-CYB	COX20	COX7B	COX4I1	ETFA	ETFB	ECSIT	COX7C	UQCRFS1	COX8A	ACAD9	NDUFC2	NDUFC1	COQ10B	COQ10A	NDUFS8	NDUFS7	NDUFS6	NDUFS5	NDUFS4	NDUFS3	NDUFS2	NDUFS1	NDUFB9	NDUFB8	NDUFB7	NDUFB6	NDUFB5	NDUFB4	NDUFB3	ETFDH	NDUFB2	NDUFB1	UQCR11	UQCR10	COX5B	COX5A	NDUFA9	NDUFA8	NDUFA7	TIMMDC1	NDUFA6	NDUFA5	NUBPL	NDUFA4	NDUFA3	NDUFA2	NDUFA1	COX6C	LRPPRC	NDUFAB1	
FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION%REACTOME%R-HSA-983231.2	Factors involved in megakaryocyte development and platelet production	ZFPM1	IFNA10	GATA6	AK3	GATA5	KIF16B	GATA4	GATA3	GATA2	KIF20A	GATA1	PHF21A	KIF20B	MICAL1	ABL1	IFNA21	NFE2	CBX5	HBG2	HBG1	KLC1	EHD1	EHD2	KLC4	EHD3	KLC3	CDK5	KLC2	MAFG	KIF3B	MAFF	RACGAP1	MAFK	RAB5A	DOCK6	IFNA5	PRKAR2B	KIF3C	DOCK5	IFNA4	DOCK4	IFNA7	DOCK3	IFNA6	IFNA1	KIF18A	DOCK9	KIF18B	DOCK8	DOCK7	KIF4B	IFNA2	KIF4A	HBB	HBD	IFNA8	AKAP10	SIN3A	CDK2	KIF11	HMG20B	RAC1	ITPK1	RBSN	RAD51B	KIF15	RAD51C	KIF19	IRF1	CAPZB	IRF2	DOCK2	KIF13B	DOCK1	HDAC2	KIF1C	JAK2	HDAC1	LRRC16A	AKAP1	KIF1B	CDC42	KIF1A	MFN1	MFN2	SH2B3	SH2B1	IFNB1	KIF25	CABLES1	CABLES2	KIF23	WEE1	KIF22	KIF6	KIF27	KIF9	KIFC2	KIF2A	KIFC1	KIF2C	KIF2B	CENPE	KIF26A	CAPZA1	KIF26B	CAPZA2	VPS45	HIST2H3A	HIST2H3D	HIST2H3C	HIST1H3J	PRKACG	HIST1H3A	PRKACB	HIST1H3F	HIST1H3G	HIST1H3H	PRKAR1B	HIST1H3I	HIST1H3B	PRKAR1A	HIST1H3C	HIST1H3D	HIST1H3E	KIF3A	PRKACA	PRKAR2A	H3F3B	KIF5B	KIF5A	H3F3A	KDM1A	KIF21A	JMJD1C	KIF21B	DOCK10	KIFAP3	DOCK11	MYB	IFNA13	IFNA14	IFNA16	IFNA17	HBE1	ZFPM2	TP53	
SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA(PHE)%REACTOME%R-HSA-6782861.2	Synthesis of wybutosine at G37 of tRNA(Phe)	TYW5	TYW3	TRMT5	TYW1	TRMT12	LCMT2	
PACKAGING OF EIGHT RNA SEGMENTS%REACTOME%R-HSA-168303.3	Packaging of Eight RNA Segments	
VARIANT SLC6A20 CONTRIBUTES TOWARDS HYPERGLYCINURIA (HG) AND IMINOGLYCINURIA (IG)%REACTOME%R-HSA-5619101.1	Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	SLC6A20	
AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1%REACTOME DATABASE ID RELEASE 74%349425	Autodegradation of the E3 ubiquitin ligase COP1	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	RFWD2	ATM	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	TP53	
INTEGRIN SIGNALING%REACTOME DATABASE ID RELEASE 74%354192	Integrin signaling	CSK	SRC	RAP1B	RAP1A	SHC1	RASGRP2	RASGRP1	PDPK1	FN1	SOS1	APBB1IP	PTPN1	SYK	CRK	RAPGEF3	BCAR1	ITGB3	RAPGEF4	AKT1	FGB	FGA	ITGA2B	VWF	FGG	TLN1	PTK2	
LIPOPROTEIN METABOLISM%REACTOME%R-HSA-174824.4	Lipoprotein metabolism	A2M	ABCG1	HDLBP	PCSK9	AP2A1	ZDHHC8	VLDLR	PCSK6	AP2A2	LIPA	PCSK5	LIPC	CREB3L3	LIPG	LDLRAP1	AP2M1	CUBN	MYLIP	AMN	CLTC	APOA2	CLTA	LSR	APOA1	APOA4	APOA5	SOAT1	NPC1	SOAT2	NPC2	ANGPTL3	ANGPTL4	LPA	CES3	CETP	SAR1B	C19orf80	MTTP	LPL	FURIN	LCAT	LMF2	LMF1	AP2S1	APOF	APOE	APOB	LDLR	FGF21	GPIHBP1	ABCA1	MBTPS1	NR1H2	APOC4	APOBR	APOC3	NR1H3	AP2B1	NCEH1	APOC2	ALB	APOC1	P4HB	MBTPS2	PRKACG	PRKACB	PRKACA	
RECYCLING OF EIF2:GDP%REACTOME%R-HSA-72731.2	Recycling of eIF2:GDP	EIF2S3	EIF2B2	EIF2B1	EIF2B5	EIF2B4	EIF2S2	EIF2B3	EIF2S1	
DIGESTION%REACTOME%R-HSA-8935690.5	Digestion	PNLIPRP1	GUCY2C	CHIA	MGAM	AMY2A	AMY1A	ALPI	AMY2B	TREH	AMY1B	AMY1C	GUCA2B	GUCA2A	LIPF	CHIT1	CLPS	SI	PIR	LCT	PNLIP	PNLIPRP3	
MICRORNA (MIRNA) BIOGENESIS%REACTOME DATABASE ID RELEASE 74%203927	MicroRNA (miRNA) biogenesis	POLR2E	BCDIN3D	POLR2F	XPO5	DROSHA	POLR2G	DGCR8	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	AGO3	AGO4	AGO1	AGO2	RAN	PRKRA	DICER1	POLR2A	TARBP2	POLR2B	POLR2C	POLR2D	
MEIOTIC RECOMBINATION%REACTOME DATABASE ID RELEASE 74%912446	Meiotic recombination	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	PRDM9	HIST1H2BJ	SPO11	HIST1H2BI	BRCA1	HIST1H2BL	BRCA2	NBN	TOP3A	HIST1H2BK	TEX15	MSH4	HIST2H4A	DMC1	MSH5	HIST2H4B	BLM	PSMC3IP	RBBP8	RPA1	RPA2	MRE11A	CDK2	HIST3H3	MND1	MLH1	MLH3	RAD50	RAD51C	RAD51	RPA3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	ATM	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	CDK4	HIST1H4L	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
PERK REGULATES GENE EXPRESSION%REACTOME DATABASE ID RELEASE 74%381042	PERK regulates gene expression	CEBPB	CXCL8	CEBPG	HERPUD1	CCL2	IGFBP1	HSPA5	NFYA	NFYB	NFYC	EIF2AK3	ASNS	DDIT3	ATF6	ATF3	ATF4	KHSRP	DIS3	DCP2	EIF2S2	PARN	EIF2S1	EIF2S3	EXOSC7	EXOSC6	EXOSC5	EXOSC4	EXOSC9	EXOSC8	EXOSC3	EXOSC2	EXOSC1	
INACTIVATION OF APC C VIA DIRECT INHIBITION OF THE APC C COMPLEX%REACTOME%R-HSA-141430.2	Inactivation of APC C via direct inhibition of the APC C complex	UBE2C	UBE2D1	CDC23	UBE2S	CDC26	CDC16	CDC27	ANAPC7	UBE2E1	ANAPC4	BUB1B	ANAPC5	CDC20	BUB3	ANAPC1	MAD2L1	ANAPC2	ANAPC15	ANAPC16	ANAPC10	ANAPC11	
CD163 MEDIATING AN ANTI-INFLAMMATORY RESPONSE%REACTOME%R-HSA-9662834.1	CD163 mediating an anti-inflammatory response	IL6	CD163	PLK2	MYH9	RHBDF2	ADAM17	FURIN	MAPK14	IL10	
SIGNALING BY FGFR4 IN DISEASE%REACTOME DATABASE ID RELEASE 74%5655291	Signaling by FGFR4 in disease	GAB1	NRAS	PLCG1	SOS1	HRAS	PIK3R1	FGFR4	PIK3CA	FRS2	
MATURATION OF SPIKE PROTEIN%REACTOME%R-HSA-9694548.1	Maturation of spike protein	RPN2	PRKCSH	TUSC3	RPN1	MAGT1	GANAB	FUT8	MGAT5	ST3GAL4	MGAT1	MGAT2	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	EDEM2	MOGS	DDOST	MGAT4C	DAD1	MGAT4A	MGAT4B	STT3A	MAN1B1	ST6GALNAC3	MAN2A1	ST6GALNAC4	CANX	ST6GALNAC2	
INTEGRATION OF VIRAL DNA INTO HOST GENOMIC DNA%REACTOME DATABASE ID RELEASE 74%175567	Integration of viral DNA into host genomic DNA	BANF1	HMGA1	PSIP1	
SHC-MEDIATED CASCADE:FGFR1%REACTOME DATABASE ID RELEASE 74%5654688	SHC-mediated cascade:FGFR1	FGF20	FGF1	FGF23	FGF2	FGF22	FGF3	FGF4	FGF6	NRAS	FGF9	SOS1	HRAS	FGF10	
TRAF6-MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX%REACTOME DATABASE ID RELEASE 74%937072	TRAF6-mediated induction of TAK1 complex within TLR4 complex	LY96	RPS27A	TICAM1	CD14	TRAF6	TLR4	UBA52	UBB	TAB3	TAB2	TAB1	UBC	MAP3K7	TICAM2	IRAK2	
TRANSPORT OF VITAMINS, NUCLEOSIDES, AND RELATED MOLECULES%REACTOME%R-HSA-425397.3	Transport of vitamins, nucleosides, and related molecules	SLC35B4	SLC35D1	ARL2	SLC35D2	SLCO1B1	PDZD11	SLCO2B1	SLCO1B3	SLC16A2	SLC35A2	SLC35A1	SLC35A3	SLC33A1	SLC35C1	SLCO1C1	SLC5A6	ARL2BP	SLCO4A1	ALB	SLCO4C1	SLCO1A2	SLCO2A1	SLC29A4	AVP	SLC29A1	SLC28A2	SLC28A1	SLC29A3	SLC28A3	SLC29A2	SLC25A5	LCN9	SLC25A4	SLC27A1	SLC25A6	LCN15	LCN12	LCN1	SLC27A6	APOD	SLC27A4	SLC35B3	SLC35B2	
MITOCHONDRIAL TRANSLATION INITIATION%REACTOME DATABASE ID RELEASE 74%5368286	Mitochondrial translation initiation	ICT1	GADD45GIP1	PTCD3	MRPL27	MRPL28	ERAL1	MRPL23	MRPL24	MRPL21	MRPL22	MRPL30	MRPS17	MTFMT	MRPS15	MRPS16	MRPS14	MRPS11	MRPS12	MRPL38	MRPL39	MRPS10	MRPL36	MRPL37	MRPL34	MRPL35	MRPL32	MRPL33	MRPL41	MRPL4	MRPL42	MRPL3	MRPL2	MRPL1	MRPL40	MRPL9	CHCHD1	MRPS28	MRPS26	MRPS27	MRPS24	MRPS25	MRPS22	MRPS23	MRPL49	MRPS18B	MRPS2	MRPS18A	MRPL47	MRPL48	MRPS7	MRPL45	MRPS6	MRPL46	MRPL43	MRPS5	MRPS18C	MRPL44	MRPL52	OXA1L	MRPL53	MRPL50	MRPS9	MRPL51	AURKAIP1	DAP3	MRPS35	MRPS36	MRPL18	MRPS33	MRPS34	MRPL19	MRPL16	MRPS31	MRPL17	MTIF2	MRPL14	MRPS30	MTIF3	MRPL15	MRPL12	MRPL13	MRPL57	MRPL10	MRPL54	MRPL11	MRPL55	MRPL20	
SUNITINIB-RESISTANT KIT MUTANTS%REACTOME%R-HSA-9669934.1	Sunitinib-resistant KIT mutants	KIT	
UREA CYCLE%REACTOME DATABASE ID RELEASE 74%70635	Urea cycle	SLC25A15	ARG2	SLC25A2	CPS1	ARG1	ASL	NAGS	ASS1	NMRAL1	OTC	
FCGR3A-MEDIATED IL10 SYNTHESIS%REACTOME DATABASE ID RELEASE 74%9664323	FCGR3A-mediated IL10 synthesis	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	CREB1	ADCY5	IGKV2-28	IGKV1-12	IGKV3D-20	IGKV2D-28	IGKV4-1	IGKV2D-30	IGHG4	IGKV3-11	PLCG1	LYN	IGHG1	IGKV5-2	IGHG2	HCK	PRKAR2B	SYK	PRKACG	PRKACB	IL10	ADCY9	FYN	PRKAR1B	PRKAR1A	AHCYL1	CD3G	PRKX	FCGR3A	PRKAR2A	PRKACA	FCGR1A	YES1	ITPR1	FGR	ITPR2	FCGR2A	ITPR3	PLCG2	ADCY4	ADCY3	
RNA POLYMERASE I TRANSCRIPTION INITIATION%REACTOME%R-HSA-73762.3	RNA Polymerase I Transcription Initiation	RRN3	CCNH	EHMT2	CHD4	CHD3	TTF1	TAF1D	ZNRD1	MTA1	RBBP4	TAF1B	TAF1C	POLR2E	TWISTNB	POLR2F	TBP	TAF1A	UBTF	RBBP7	POLR2H	MTA2	MTA3	MBD3	POLR2K	CD3EAP	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GATAD2B	GTF2H5	POLR1C	GATAD2A	KAT2B	CDK7	KAT2A	ERCC3	HDAC2	POLR1A	HDAC1	POLR1B	ERCC2	POLR1E	ERCC6	MNAT1	
PARADOXICAL ACTIVATION OF RAF SIGNALING BY KINASE INACTIVE BRAF%REACTOME%R-HSA-6802955.2	Paradoxical activation of RAF signaling by kinase inactive BRAF	MAPK3	RAF1	CSK	PHB	CAMK2G	SRC	RAP1B	RAP1A	MARK3	KRAS	YWHAB	NRAS	FN1	CNKSR2	HRAS	APBB1IP	CNKSR1	MAP3K11	ITGB3	ARRB1	ARAF	ARRB2	MAPK1	FGB	FGA	ITGA2B	VWF	CAMK2A	PEBP1	KSR1	FGG	TLN1	KSR2	IQGAP1	JAK2	BRAP	BRAF	MAP2K1	MAP2K2	CAMK2B	VCL	CAMK2D	
BIOSYNTHESIS OF D-SERIES RESOLVINS%REACTOME%R-HSA-9018676.1	Biosynthesis of D-series resolvins	LTA4H	HPGD	ALOX5	
IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN%REACTOME%R-HSA-1606341.2	IRF3 mediated activation of type 1 IFN	ZBP1	TBK1	IRF3	NLRP4	DTX4	
CLASS B 2 (SECRETIN FAMILY RECEPTORS)%REACTOME DATABASE ID RELEASE 74%373080	Class B 2 (Secretin family receptors)	WNT10A	FZD2	FZD5	WNT3A	FZD7	FZD4	WNT7B	PTCH2	FZD6	FZD9	SCTR	GNG12	FZD8	GNG11	WNT7A	GNG13	GCG	ADM2	GHRH	VIP	RAMP1	GNB2	GNB1	GNB4	GNB3	GNB5	GLP1R	CD55	UCN	VIPR1	WNT2B	VIPR2	SCT	IHH	ADM	PTH1R	FZD10	ADGRE1	ADGRE2	CRHBP	SHH	CYSLTR2	ADGRE5	UCN3	UCN2	ADGRE3	GNGT1	GLP2R	WNT9B	PTH2R	GNGT2	WNT9A	WNT16	GIP	ADCYAP1	SMO	WNT5A	CRH	IAPP	CALCA	RAMP2	ADCYAP1R1	RAMP3	CALCRL	PTCH1	CALCB	DHH	GIPR	PTH	GNAS	WNT8A	GNG3	WNT8B	GNG10	PTH2	PTHLH	GNG2	CRHR1	WNT11	GHRHR	GNG5	WNT6	GNG4	CALCR	GNG7	GNG8	WNT1	WNT2	WNT3	WNT4	FZD1	FZD3	WNT10B	
CONSTITUTIVE SIGNALING BY NOTCH1 HD DOMAIN MUTANTS%REACTOME DATABASE ID RELEASE 74%2691232	Constitutive Signaling by NOTCH1 HD Domain Mutants	MIB2	RPS27A	MIB1	NEURL1	UBA52	NOTCH1	ADAM10	DLL1	DLL4	ADAM17	NEURL1B	UBB	UBC	JAG2	JAG1	
NA+ CL- DEPENDENT NEUROTRANSMITTER TRANSPORTERS%REACTOME%R-HSA-442660.1	Na+ Cl- dependent neurotransmitter transporters	SLC6A19	SLC6A18	SLC22A2	SLC6A15	SLC22A1	SLC6A14	SLC6A13	SLC6A12	SLC6A11	SLC6A1	SLC6A2	SLC6A3	SLC6A5	SLC6A20	SLC6A6	SLC6A7	SLC6A9	SLC18A1	SLC18A2	
NADPH REGENERATION%REACTOME%R-HSA-389542.2	NADPH regeneration	IDH1	
IRON UPTAKE AND TRANSPORT%REACTOME%R-HSA-917937.3	Iron uptake and transport	ATP6V0C	ATP6V1B1	ABCG2	FTL	ATP6V1A	IREB2	NEDD8	CAND1	FTMT	ATP6V0A2	ATP6V1H	HMOX1	UBA52	ATP6V0A4	ATP6V1G3	ATP6V0E2	ATP6V1D	ATP6V1C1	HMOX2	ATP6V1C2	ATP6V0A1	CUL1	ATP6V1F	CYBRD1	MCOLN1	CP	UBB	TF	LCN2	ACO1	FBXL5	UBC	RPS27A	SLC46A1	STEAP3	TFRC	HFE	SLC40A1	TCIRG1	HEPH	SLC22A17	FTH1	ATP6V1E1	SKP1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	GLRX3	ATP6AP1	SLC11A2	TFR2	ATP6V1B2	ATP6V0D1	STEAP2	ATP6V0D2	
GABA SYNTHESIS%REACTOME DATABASE ID RELEASE 74%888568	GABA synthesis	GAD1	GAD2	
DEFECTIVE MMAA CAUSES METHYLMALONIC ACIDURIA TYPE CBLA%REACTOME%R-HSA-3359475.1	Defective MMAA causes methylmalonic aciduria type cblA	MMAA	MUT	
NEF MEDIATED DOWNREGULATION OF CD28 CELL SURFACE EXPRESSION%REACTOME DATABASE ID RELEASE 74%164939	Nef mediated downregulation of CD28 cell surface expression	CD28	AP2M1	
COLLAGEN CHAIN TRIMERIZATION%REACTOME%R-HSA-8948216.2	Collagen chain trimerization	COL10A1	COL28A1	COL27A1	COL24A1	COL22A1	COL1A1	COL3A1	COL1A2	COL2A1	COL4A2	COL5A1	COL9A1	COL4A1	COL9A3	COL6A2	COL9A2	COL18A1	COL4A4	COL14A1	COL7A1	COL5A3	COL4A3	COL5A2	COL6A1	COL20A1	COL8A2	COL4A6	COL21A1	COL6A3	COL4A5	COL8A1	COL6A6	COL6A5	COL16A1	COL12A1	COL25A1	COL23A1	COL15A1	COL17A1	COL13A1	COL19A1	COL11A1	COL11A2	COL26A1	
OLEOYL-PHE METABOLISM%REACTOME DATABASE ID RELEASE 74%9673163	Oleoyl-phe metabolism	PM20D1	
NTF3 ACTIVATES NTRK2 (TRKB) SIGNALING%REACTOME%R-HSA-9025046.1	NTF3 activates NTRK2 (TRKB) signaling	NTF3	NTRK2	
VIRION ASSEMBLY AND RELEASE%REACTOME%R-HSA-9679509.2	Virion Assembly and Release	
DEFECTIVE SLC2A2 CAUSES FANCONI-BICKEL SYNDROME (FBS)%REACTOME DATABASE ID RELEASE 74%5619098	Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS)	SLC2A2	
DISEASES OF CELLULAR SENESCENCE%REACTOME DATABASE ID RELEASE 74%9630747	Diseases of Cellular Senescence	CDK6	CDKN2A	CDK4	
AMINE LIGAND-BINDING RECEPTORS%REACTOME%R-HSA-375280.2	Amine ligand-binding receptors	CHRM2	CHRM3	CHRM1	CHRM4	CHRM5	HTR2B	HTR2C	ADRA1D	ADRB1	HTR2A	ADRB2	ADRA1B	HTR4	ADRA1A	HRH1	HTR6	HTR7	HRH3	HRH2	HRH4	DRD1	DRD2	DRD3	DRD4	DRD5	TAAR8	HTR1E	TAAR9	HTR1F	TAAR6	HTR1D	HTR1A	HTR1B	TAAR5	TAAR2	ADRA2C	HTR5A	TAAR1	ADRA2A	GPR143	ADRB3	
CLEAVAGE OF THE DAMAGED PURINE%REACTOME DATABASE ID RELEASE 74%110331	Cleavage of the damaged purine	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST3H3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	MPG	HIST1H2AJ	OGG1	TINF2	TERF1	TERF2	NEIL3	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
SENSING OF DNA DOUBLE STRAND BREAKS%REACTOME DATABASE ID RELEASE 74%5693548	Sensing of DNA Double Strand Breaks	NBN	KPNA2	ATM	MRE11A	KAT5	RAD50	
DEFECTIVE ABCA3 CAUSES SMDP3%REACTOME DATABASE ID RELEASE 74%5683678	Defective ABCA3 causes SMDP3	ABCA3	
PYROPHOSPHATE HYDROLYSIS%REACTOME DATABASE ID RELEASE 74%71737	Pyrophosphate hydrolysis	PPA1	PPA2	
DEGRADATION OF GLI2 BY THE PROTEASOME%REACTOME%R-HSA-5610783.1	Degradation of GLI2 by the proteasome	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	CSNK1A1	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	CUL1	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	PRKACG	PRKACB	RBX1	GSK3B	PRKACA	BTRC	PSMD8	SKP1	PSMD9	GLI2	PSMD6	PSMD7	PSMD4	SUFU	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
POST-TRANSLATIONAL MODIFICATION: SYNTHESIS OF GPI-ANCHORED PROTEINS%REACTOME%R-HSA-163125.2	Post-translational modification: synthesis of GPI-anchored proteins	FOLR2	RECK	MDGA1	SPRN	PIGS	CPM	LY6K	PIGU	PGAP1	PIGT	PIGO	PSCA	GPAA1	PIGN	PIGP	PIGZ	PIGW	MSLN	PIGV	PIGY	PRSS21	PIGX	FCGR3B	PRND	TECTA	TECTB	CD52	PLAUR	RTN4RL2	IZUMO1R	ALPPL2	GPIHBP1	PIGC	DPM1	PIGB	DPM2	DPM3	NRN1L	CEACAM7	RTN4RL1	PIGA	CD109	CEACAM5	PIGK	LY6D	SPACA4	PIGM	PIGL	PIGG	LY6H	PIGF	GPLD1	PIGH	LY6E	NRN1	NTM	MFI2	TEX101	LYPD1	LYPD2	LYPD3	LYPD4	THY1	LYPD5	ART3	ART4	OTOA	LY6G6C	LY6G6D	OPCML	NTNG1	NTNG2	NEGR1	CNTN5	ALPI	LSAMP	GP2	PLET1	BST1	VNN1	VNN2	RAET1G	VNN3	XPNPEP2	LYPD6B	RAET1L	ALPL	CNTN3	CNTN4	MDGA2	ULBP2	
LEISHMANIA PHAGOCYTOSIS%REACTOME DATABASE ID RELEASE 74%9664417	Leishmania phagocytosis	MAPK3	IGKV2-28	IGKV1-12	IGKV3D-20	IGKV2D-28	ABL1	IGKV4-1	IGKV2D-30	IGKV3-11	LYN	IGKV5-2	HCK	MAPK1	CD3G	CYFIP2	NCKAP1	FCGR3A	CYFIP1	RAC1	WIPF1	YES1	ARPC1B	FGR	WIPF2	ARPC1A	VAV1	WIPF3	BRK1	WASL	ACTB	DOCK1	ACTG1	NCK1	ACTR3	VAV3	ACTR2	CDC42	VAV2	MYH2	ELMO1	BTK	ELMO2	WAS	NCKIPSD	NCKAP1L	WASF1	WASF2	WASF3	MYO10	MYO5A	ARPC4	MYO9B	ARPC5	BAIAP2	MYO1C	ABI2	ARPC2	ARPC3	ABI1	MYH9	IGHG4	IGHG1	IGHG2	SYK	CRK	FYN	PTK2	
PHENYLKETONURIA%REACTOME%R-HSA-2160456.2	Phenylketonuria	PAH	
DEFECTIVE SLC34A2 CAUSES PULMONARY ALVEOLAR MICROLITHIASIS (PALM)%REACTOME DATABASE ID RELEASE 74%5619045	Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM)	SLC34A2	
TRANSPORT OF GAMMA-CARBOXYLATED PROTEIN PRECURSORS FROM THE ENDOPLASMIC RETICULUM TO THE GOLGI APPARATUS%REACTOME DATABASE ID RELEASE 74%159763	Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus	F2	F7	BGLAP	F10	PROZ	F9	GAS6	PROC	PROS1	
DEFECTIVE ALG2 CAUSES ALG2-CDG (CDG-1I)%REACTOME%R-HSA-4549349.1	Defective ALG2 causes ALG2-CDG (CDG-1i)	ALG2	
DEFECTIVE ALG11 CAUSES ALG11-CDG (CDG-1P)%REACTOME DATABASE ID RELEASE 74%4551295	Defective ALG11 causes ALG11-CDG (CDG-1p)	ALG11	
ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT (ESCRT)%REACTOME%R-HSA-917729.1	Endosomal Sorting Complex Required For Transport (ESCRT)	VPS37C	VPS37D	VPS37A	VPS37B	STAM	SNF8	HGS	CHMP2B	CHMP2A	CHMP4C	CHMP4B	UBAP1	CHMP3	UBA52	CHMP4A	CHMP6	CHMP7	STAM2	VPS25	VPS28	CHMP5	UBB	UBC	RPS27A	TSG101	VPS4B	VPS4A	MVB12B	MVB12A	VPS36	VTA1	
GLYCOLYSIS%REACTOME DATABASE ID RELEASE 74%70171	Glycolysis	NUP62	NDC1	SEC13	NUP133	NUP50	PGM2L1	NUP54	PPP2CA	PPP2CB	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	GPI	ADPGK	NUP107	ENO1	NUP188	ENO2	ENO3	HK2	HK1	HK3	PPP2R1B	TPI1	PGAM1	PGAM2	BPGM	GAPDHS	PGP	ALDOC	NUP214	ALDOB	NUP210	ALDOA	GAPDH	PFKFB2	PFKFB1	PFKFB4	PFKFB3	PGK1	NUP93	PGK2	PFKL	GNPDA1	GNPDA2	PFKM	PFKP	NUP205	POM121	AAAS	NUP160	PRKACG	PRKACB	NUP85	TPR	NUP88	PPP2R1A	PRKACA	GCKR	NUP155	GCK	PPP2R5D	NUP153	
MITOCHONDRIAL TRANSLATION ELONGATION%REACTOME%R-HSA-5389840.1	Mitochondrial translation elongation	ICT1	GADD45GIP1	PTCD3	MRPL27	MRPL28	ERAL1	MRPL23	MRPL24	MRPL21	MRPL22	MRPL30	MRPS17	MRPS15	MRPS16	MRPS14	MRPS11	MRPS12	MRPL38	MRPL39	MRPS10	MRPL36	MRPL37	MRPL34	MRPL35	MRPL32	MRPL33	MRPL41	MRPL4	MRPL42	MRPL3	MRPL2	MRPL1	MRPL40	MRPL9	CHCHD1	MRPS28	MRPS26	MRPS27	MRPS24	GFM1	MRPS25	TSFM	MRPS22	MRPS23	TUFM	MRPL49	MRPS18B	MRPS2	MRPS18A	MRPL47	MRPL48	MRPS7	MRPL45	MRPS6	MRPL46	MRPL43	MRPS5	MRPS18C	MRPL44	MRPL52	OXA1L	MRPL53	MRPL50	MRPS9	MRPL51	AURKAIP1	DAP3	MRPS35	MRPS36	MRPL18	MRPS33	MRPS34	MRPL19	MRPL16	MRPS31	MRPL17	MRPL14	MRPS30	MRPL15	MRPL12	MRPL13	MRPL57	MRPL10	MRPL54	MRPL11	MRPL55	MRPL20	
ACTIVATED NTRK3 SIGNALS THROUGH RAS%REACTOME%R-HSA-9034864.1	Activated NTRK3 signals through RAS	NRAS	NTRK3	SOS1	HRAS	NTF3	
PCNA-DEPENDENT LONG PATCH BASE EXCISION REPAIR%REACTOME DATABASE ID RELEASE 74%5651801	PCNA-Dependent Long Patch Base Excision Repair	RFC5	RFC3	FEN1	PCNA	RPA1	RFC4	RPA2	RFC1	LIG1	RFC2	POLE4	POLD3	POLB	POLD4	RPA3	POLE2	POLD1	APEX1	POLE3	POLD2	POLE	
VIRAL MESSENGER RNA SYNTHESIS%REACTOME%R-HSA-168325.4	Viral Messenger RNA Synthesis	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	AAAS	POLR2A	POLR2B	NUP160	POLR2C	NUP85	POLR2D	TPR	POLR2E	POLR2F	NUP88	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	NUP43	POLR2J	RAE1	POLR2K	RANBP2	POLR2L	NUP155	NUP35	NUPL2	NUP37	NUP107	NUP153	NUP188	
G1 S DNA DAMAGE CHECKPOINTS%REACTOME%R-HSA-69615.2	G1 S DNA Damage Checkpoints	PSMA6	PSMA3	CDKN1A	PSMA4	CDKN1B	PSMA1	PHF20	PSMA2	CHEK2	PSME3	CHEK1	PSME4	ZNF385A	PSME1	CDC25A	PSME2	PCBP4	PSMD10	MDM2	PSMB11	MDM4	UBA52	PSMD12	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	CCNE2	CCNE1	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CDK2	RFWD2	ATM	CDKN2A	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	TP53	
TOLL-LIKE RECEPTOR CASCADES%REACTOME DATABASE ID RELEASE 74%168898	Toll-like Receptor Cascades	RIPK3	RIPK2	IRAK3	IRAK4	FOS	CREB1	TIRAP	DNM1	UBE2D1	TBK1	DUSP4	DNM2	TLR1	IRF3	DNM3	TRAF3	IRF7	UBA52	PELI1	TLR8	TLR7	TLR10	BPI	TLR6	TLR5	DUSP6	BIRC2	CUL1	DUSP7	TLR3	TLR2	BIRC3	UNC93B1	UBB	PELI3	PELI2	NOD1	NOD2	UBC	TANK	TLR9	MAPK9	MAPK8	MAPK7	RPS27A	MAP3K1	S100B	PPP2CA	MAPK10	TNIP2	PPP2CB	SAA1	PTPN4	MAPK1	RBSN	PLCG2	MAP2K1	PPP2R5D	IKBKB	ECSIT	PIK3C3	IKBKG	RPS6KA3	MAP3K7	CHUK	RPS6KA2	RPS6KA1	MAPK3	UBE2D2	PTPN11	TRAF6	UBE2V1	CTSV	CTSS	RELA	UBE2N	TAB3	TAB2	CTSL	TAB1	MAPKAPK2	CTSK	IRAK2	NFKB1	NFKBIA	CTSB	NFKBIB	MAPK14	MAPK11	PPP2R1B	BTK	TICAM2	LY96	APOB	TICAM1	CASP8	RIPK1	CD14	FADD	TLR4	ATF1	APP	ATF2	UBE2D3	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	S100A1	CD180	MAP3K8	CNPY3	VRK3	SIGIRR	FGB	PPP2R1A	MAPKAPK3	FGA	S100A9	S100A8	AGER	HSP90B1	BTRC	SOCS1	IRAK1	S100A12	MAP2K7	FGG	PIK3R4	MAP2K6	JUN	SKP1	LY86	NFKB2	MYD88	LGMN	ITGAM	ITGB2	FBXW11	HMGB1	EEA1	NKIRAS1	NKIRAS2	LBP	CD36	RPS6KA5	IKBKE	DUSP3	
DEFECTIVE SLC6A18 MAY CONFER SUSCEPTIBILITY TO IMINOGLYCINURIA AND OR HYPERGLYCINURIA%REACTOME DATABASE ID RELEASE 74%5619079	Defective SLC6A18 may confer susceptibility to iminoglycinuria and or hyperglycinuria	SLC6A18	
TOLL LIKE RECEPTOR 2 (TLR2) CASCADE%REACTOME DATABASE ID RELEASE 74%181438	Toll Like Receptor 2 (TLR2) Cascade	RPS6KA1	RIPK2	MAPK3	IRAK3	IRAK4	FOS	CREB1	TIRAP	DUSP4	TLR1	TRAF6	PELI1	UBA52	UBE2V1	TLR6	DUSP6	DUSP7	CUL1	RELA	TLR2	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	BTK	LY96	CD14	TLR4	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	SIGIRR	PPP2R1A	MAPKAPK3	AGER	BTRC	SOCS1	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	CD36	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
RESISTANCE OF ERBB2 KD MUTANTS TO SAPITINIB%REACTOME DATABASE ID RELEASE 74%9665244	Resistance of ERBB2 KD mutants to sapitinib	ERBB2	HSP90AA1	CDC37	ERBB2IP	
RHO GTPASES ACTIVATE IQGAPS%REACTOME%R-HSA-5626467.1	RHO GTPases activate IQGAPs	IQGAP3	MEN1	IQGAP1	CTNNB1	CDH1	CDC42	RAC1	CLIP1	CTNNA1	IQGAP2	
DEFECTIVE ABCA3 CAUSES SMDP3%REACTOME%R-HSA-5688399.2	Defective ABCA3 causes SMDP3	ABCA3	
ACTIVATION OF THE TFAP2 (AP-2) FAMILY OF TRANSCRIPTION FACTORS%REACTOME%R-HSA-8866907.2	Activation of the TFAP2 (AP-2) family of transcription factors	TFAP2D	TFAP2E	CITED1	CITED2	CITED4	YEATS4	CREBBP	EP300	TFAP2A	TFAP2B	WWOX	TFAP2C	
ATTACHMENT AND ENTRY%REACTOME%R-HSA-9694614.1	Attachment and Entry	ACE2	CTSL	TMPRSS2	VCP	FURIN	
RESISTANCE OF ERBB2 KD MUTANTS TO AFATINIB%REACTOME DATABASE ID RELEASE 74%9665249	Resistance of ERBB2 KD mutants to afatinib	ERBB2	HSP90AA1	CDC37	ERBB2IP	
UNFOLDED PROTEIN RESPONSE (UPR)%REACTOME DATABASE ID RELEASE 74%381119	Unfolded Protein Response (UPR)	CREB3L2	TSPYL2	DDX11	PLA2G4B	WIPI1	PDIA6	PDIA5	ERN1	CREB3	DCSTAMP	CTDSP2	KDELR3	DNAJB11	PREB	CUL7	CXXC1	SHC1	ADD1	EXTL2	EXTL1	LMNA	SSR1	DNAJB9	EXTL3	KHSRP	SULT1A3	SEC31A	DIS3	ZBTB17	KLHDC3	WFS1	EDEM1	GFPT1	SYVN1	DCP2	YIF1A	EIF2S2	CREBRF	PARN	EIF2S1	SRPRB	EIF2S3	HYOU1	EXOSC7	HDGF	EXOSC6	TPP1	EXOSC5	CREB3L3	EXOSC4	EXOSC9	EXOSC8	EXOSC3	EXOSC2	EXOSC1	CALR	DNAJC3	CEBPB	CXCL8	CEBPG	HERPUD1	CCL2	IGFBP1	ARFGAP1	MBTPS1	HSPA5	NFYA	NFYB	NFYC	EIF2AK3	ASNS	DDIT3	ATF6	ATF3	ATF4	MBTPS2	DCTN1	GOSR2	HSP90B1	PPP2R5B	TLN1	GSK3A	ACADVL	FKBP14	SRPR	MYDGF	TATDN2	SERP1	ATP6V0D1	CREB3L4	CREB3L1	
SYNTHESIS OF SUBSTRATES IN N-GLYCAN BIOSYTHESIS%REACTOME%R-HSA-446219.2	Synthesis of substrates in N-glycan biosythesis	PMM2	DOLK	NAGK	GLB1	DOLPP1	ST3GAL4	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	ST6GALNAC3	ST6GALNAC4	GFPT1	DPM1	DPM2	SLC35A1	DPM3	SLC35C1	ST6GALNAC1	CMAS	MPI	GMPPB	NANP	FPGT	GMPPA	PGM3	GNPNAT1	NANS	NUDT14	ST6GAL2	ALG5	RENBP	DHDDS	MVD	ST6GALNAC5	ST6GALNAC6	GNE	TSTA3	UAP1	NPL	FUOM	NEU2	NEU3	NEU4	GMDS	AMDHD2	NEU1	SLC17A5	ST8SIA4	ST8SIA5	ST3GAL5	ST3GAL6	ST8SIA6	FUK	CTSA	NUS1	PMM1	ST8SIA1	ST8SIA2	GFPT2	SRD5A3	ST6GALNAC2	ST8SIA3	
AKT-MEDIATED INACTIVATION OF FOXO1A%REACTOME%R-HSA-211163.1	AKT-mediated inactivation of FOXO1A	AKT1	FOXO1	AKT2	AKT3	
PURINE SALVAGE%REACTOME%R-HSA-74217.4	Purine salvage	ADA	GMPR2	ADK	GMPR	AMPD1	AMPD2	AMPD3	DCK	APRT	ADAL	DGUOK	PNP	HPRT1	
ESTROGEN-DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR-MEMBRANE SIGNALING%REACTOME%R-HSA-9634638.1	Estrogen-dependent nuclear events downstream of ESR-membrane signaling	MAPK3	AREG	BCL2	AKT1	CDKN1B	SRF	FOS	CREB1	FOXO3	EPGN	UHMK1	MAPK1	CCND1	EREG	BTC	EGF	TGFA	EGFR	XPO1	PTK2	ELK1	AKT2	AKT3	HBEGF	
RNA POLYMERASE III TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%74158	RNA Polymerase III Transcription	GTF3C1	GTF3C2	GTF3C3	CRCP	GTF3C4	NFIX	GTF3C5	GTF3C6	SNAPC5	SNAPC1	SNAPC2	SNAPC3	SNAPC4	ZNF143	POU2F1	POLR2E	BRF2	POLR2F	TBP	SSB	BRF1	POLR2H	POLR3GL	GTF3A	POLR3A	POLR3B	POLR2K	NFIA	POLR2L	POLR3C	NFIB	POLR3D	NFIC	POLR3E	POLR1C	POLR3F	POLR3G	POLR3H	BDP1	POLR3K	
XAV939 INHIBITS TANKYRASE, STABILIZING AXIN%REACTOME%R-HSA-5545619.1	XAV939 inhibits tankyrase, stabilizing AXIN	TNKS2	TNKS	
TOLL LIKE RECEPTOR TLR6:TLR2 CASCADE%REACTOME DATABASE ID RELEASE 74%168188	Toll Like Receptor TLR6:TLR2 Cascade	RPS6KA1	RIPK2	MAPK3	IRAK3	IRAK4	FOS	CREB1	TIRAP	DUSP4	TLR1	TRAF6	PELI1	UBA52	UBE2V1	TLR6	DUSP6	DUSP7	CUL1	RELA	TLR2	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	BTK	LY96	CD14	TLR4	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	SIGIRR	PPP2R1A	MAPKAPK3	AGER	BTRC	SOCS1	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	CD36	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
TELOMERE C-STRAND (LAGGING STRAND) SYNTHESIS%REACTOME DATABASE ID RELEASE 74%174417	Telomere C-strand (Lagging Strand) Synthesis	POLA2	TEN1	DNA2	TINF2	TERF1	TERF2	POT1	TERF2IP	ACD	BLM	RFC5	RFC3	FEN1	PCNA	RPA1	RFC4	RPA2	RFC1	LIG1	RFC2	POLD3	POLD4	RPA3	POLD1	POLD2	PRIM2	DSCC1	PRIM1	CHTF18	WRN	CHTF8	OBFC1	CTC1	POLA1	
BIOSYNTHESIS OF ELECTROPHILIC Ω-3 PUFA OXO-DERIVATIVES%REACTOME DATABASE ID RELEASE 74%9027604	Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives	PTGS2	ALOX5	
DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR (BCR)%REACTOME DATABASE ID RELEASE 74%1168372	Downstream signaling events of B Cell Receptor (BCR)	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	NFATC1	PSME4	PSME1	PSME2	CARD11	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	BCL10	PSMB10	RASGRP1	MALT1	PSMA7	NRAS	CUL1	RELA	PSMA8	PSMB6	HRAS	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	REL	NFKBIE	NFKBIB	PRKCB	PPIA	RASGRP3	NFATC3	NFATC2	FKBP1A	PPP3CA	PPP3CB	BTRC	PSMD8	SKP1	IKBKB	PSMD9	PPP3R1	PSMD6	PSMD7	PSMD4	PSMD5	FBXW11	PSMD2	PSMD3	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	
TIE2 SIGNALING%REACTOME%R-HSA-210993.1	Tie2 Signaling	ANGPT1	PTPN11	TEK	SHC1	PIK3CB	GRB7	ANGPT4	ANGPT2	NRAS	DOK2	GRB14	SOS1	HRAS	PIK3R2	PIK3R1	PIK3CA	
INTERACTIONS OF TAT WITH HOST CELLULAR PROTEINS%REACTOME%R-HSA-176034.2	Interactions of Tat with host cellular proteins	CDK9	CCNT1	
NEGATIVE REGULATION OF FGFR4 SIGNALING%REACTOME%R-HSA-5654733.1	Negative regulation of FGFR4 signaling	MAPK3	PTPN11	FGF20	UBA52	FGF23	CBL	FGF16	MKNK1	FGF19	UBB	FGF18	SPRY2	FGFR4	UBC	RPS27A	PPP2CA	PPP2CB	MAPK1	PPP2R1A	KLB	FRS2	FGF1	FGF2	FGF4	FGF6	FGF9	BRAF	
SIGNALING BY FGFR IN DISEASE%REACTOME DATABASE ID RELEASE 74%1226099	Signaling by FGFR in disease	GAB2	GAB1	NRAS	PLCG1	SOS1	HRAS	ERLIN2	GTF2F1	GTF2F2	STAT5A	STAT5B	FGF1	FGF2	FGF3	FGF4	FGFR1OP	FGF6	FGF7	FGF9	FGF20	FGF23	FGF22	FGF16	FGF18	PIK3R1	FGFR4	PIK3CA	POLR2A	POLR2B	POLR2C	FGF10	NCBP1	POLR2D	NCBP2	POLR2E	POLR2F	POLR2G	POLR2H	ZMYM2	POLR2I	FGFR1OP2	POLR2J	TRIM24	MYO18A	POLR2K	LRRFIP1	POLR2L	FRS2	BCR	BAG4	CUX1	CPSF6	STAT1	STAT3	FGFR3	FGFR2	FGFR1	
DEVELOPMENTAL BIOLOGY%REACTOME%R-HSA-1266738.7	Developmental Biology	SH3KBP1	KRT24	ADIRF	KRT23	KRT20	ROBO1	KRT28	KRT27	KRT26	PRX	KRT25	KRTAP9-7	KRTAP9-6	KRTAP9-4	KRTAP9-3	KRTAP9-2	KRTAP9-1	KRT35	KRT34	KRT32	KRT31	KRTAP9-9	KRTAP9-8	KRT39	KRT38	KRT37	KRT36	SPRR3	CSTA	CXCR4	AKAP5	DRP2	CTNNA2	TBL1X	SUZ12	SCD5	KRT13	KRT12	KRT10	KRT19	KRT18	KRT17	KRT16	KRT15	PIK3CD	KRT14	IRS2	NEUROG3	PIK3CB	CDK5R1	KRTAP24-1	ARHGAP39	ARHGAP35	NRCAM	KRT6C	KRT6B	KRT6A	KRT71	KRTAP13-2	KRTAP13-1	DSCAM	KRTAP13-4	KRTAP13-3	KRT79	KRT78	KAZN	KRT77	KRT76	KRT75	KRT74	KRT73	LOR	KRT72	TBL1XR1	EFNA5	EFNA4	KRT40	EFNB2	SDCBP	EFNB1	EFNB3	SMAD4	EFNA1	EFNA3	LIN28A	EFNA2	FES	MYF6	MYF5	KRTAP22-1	USP33	SLC2A4	KDM6A	KRTAP11-1	POLR2A	DCC	POLR2B	GAP43	POLR2C	THRAP3	DCX	POLR2D	CDH15	KRT82	POLR2E	KRT81	POLR2F	KRT80	KRT86	POLR2G	KRT85	POLR2H	KRT84	POLR2I	KRT83	POLR2J	FAM120B	CLASP2	POLR2K	LGI1	POLR2L	LGI4	LGI3	LGI2	PDX1	DEK	MEIS1	PMP22	PABPC1	HSPA8	MAPK14	MAPK11	ARPC1B	EIF4G1	ARPC1A	WASL	ACTB	ACTG1	NCK1	ACTR3	VAV3	ACTR2	VAV2	MYO10	ARPC4	MYO9B	ARPC5	ARPC2	ARPC3	PRKACG	PRKACB	RBX1	FRS2	PRKAR2A	TLN1	GRIN2B	PTK2	NUMB	ARTN	RET	GFRA1	GAB2	GFRA3	GFRA2	GFRA4	RANBP9	GRIN1	ITGA2B	FGF2	NRTN	MAP2K1	MAP2K2	SHC3	PSPN	GDNF	PTPRA	FGF10	ITGB3	RASA1	MET	CDKN1A	NCAM1	PTPN11	MAPK12	MEF2A	MEF2C	MAP2K6	JUN	CD36	DNM1	DNM2	DNM3	MAPK8	MAPK7	KIF4B	KIF4A	CTNNA1	PPP3CB	LEF1	ST8SIA4	MYB	ST8SIA2	FOXO1	GATA2	ABL1	CDK5	CTNNB1	FOXO3	NCAN	RAC1	DOCK1	HDAC2	CDC42	ARHGEF11	ARHGEF12	ROCK1	SEMA4D	ROCK2	LIMK2	LIMK1	RHOC	RHOA	MYL12B	RHOB	RND1	MYL6	GRB7	ERBB2	MYH9	DOK2	MYH14	MYH11	PLXNB1	MYH10	MYL9	STAT3	RPS6KA3	RPS6KA6	RPS6KA2	RPS6KA1	MAPK3	SHC1	GAB1	EGFR	NRAS	PLCG1	SOS1	HRAS	AP2A1	VLDLR	PCSK6	AP2A2	AP2M1	ANGPTL4	LPL	AP2S1	AP2B1	PRKACA	HSP90AA1	AJUBA	UBA52	UBB	UBC	RPS27A	CLASP1	CEBPB	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	CSNK2A1	SRC	CSNK2A2	CSNK2B	SMAD2	SMAD3	TGFB1	MAML2	MAML1	PSEN2	RBPJ	APH1A	APH1B	EP300	HES1	PSENEN	CREB1	CNTN1	MAML3	MAMLD1	EIF4A3	CASC3	MAGOH	NCBP1	NCBP2	RBM8A	UPF3B	MAGOHB	RNPS1	CLTC	CLTA	YES1	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	SPTAN1	HIST1H2AJ	ANK2	ANK3	PRKCA	ANK1	SPTB	SPTBN4	SPTBN5	HIST2H3A	INS	SPTA1	HIST1H2BF	HIST1H2BE	HIST1H2BH	SPTBN1	HIST1H2BG	HIST2H3D	SPTBN2	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	RBBP4	HIST1H3F	HIST1H3G	HIST1H3H	RBBP7	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	KAT2B	H3F3A	KAT2A	H2BFS	HIST1H4A	SPI1	HIST1H4B	ITSN1	HIST1H4H	LIPJ	HIST1H4I	DPYSL4	HIST1H4J	DPYSL5	HIST1H4C	DPYSL2	HIST1H4D	DPYSL3	HIST1H4E	LIPN	HIST1H4F	LIPM	HIST2H2AA3	LIPK	HIST2H2AA4	PKNOX1	MEF2B	UNC5A	UNC5B	UNC5C	HIST2H2AC	UNC5D	H2AFJ	ISL1	RFX6	NGEF	FLG	KRTAP27-1	AGAP2	KRTAP5-10	H2AFZ	KRTAP5-11	H2AFX	PIP5K1C	H2AFV	PPARGC1A	KRTAP16-1	HIST2H2BE	JUP	NR2F2	HIST4H4	L1CAM	PBX1	FLI1	NANOG	EZH2	MED19	HIST1H2BN	CTCF	HIST1H2BM	MED16	MED15	HIST1H2BO	MED18	HIST1H2BJ	MED17	HIST1H2BI	MED12	HIST1H2BL	MED11	CASP14	MED14	HIST1H2BK	MED13	MED10	HIST2H4A	MYOG	UPF2	HIST2H4B	LYPLA2	MAPK1	LEFTY1	MED27	MED26	MED29	POU5F1	CDK2	MED28	MED23	MED22	MED25	MED24	MED21	MED20	PPARG	PPARA	DSCAML1	KRTAP25-1	ADAM22	ADAM23	ZSWIM8	KRTAP2-4	KRTAP2-3	KRTAP2-2	ZNF467	KRTAP2-1	MEF2D	LEFTY2	FABP4	AGRN	PTF1A	NAB1	NAB2	MSI1	YY1	ADIPOQ	PIAS2	MAG	PKP2	PKP1	PKP4	PKP3	UTRN	DSC1	DSC2	DSC3	KMT2D	KMT2A	KMT2C	RAP1GAP	MED30	MED31	CLTCL1	KRTAP4-4	KRTAP4-3	MBP	KRTAP4-2	KRTAP4-1	KRTAP4-9	KRTAP4-8	KRTAP4-7	KRTAP4-6	KRTAP4-5	DRAP1	CXCL12	PTPRC	CNTNAP1	HSP90AB1	IAPP	ONECUT3	ONECUT1	NCK2	ITGAV	NEO1	DSP	ADGRV1	ITGA2	ITGA1	PSMD8	ZNF638	DSG1	PSMD9	ETF1	PSMD6	DSG2	PSMD7	DSG3	PSMD4	DSG4	PSMD5	ITGA9	PSMD2	KRTAP29-1	PSMD3	NTN4	WNT1	PSMD1	NTN1	NTN3	E2F1	KRTAP6-2	PSMA5	KRTAP6-1	WNT10B	PSMA6	KRTAP6-3	PSMA3	NELL2	PSMA4	RQCD1	PSMA1	CCNC	PSMA2	EPHB2	PSME3	EPHB1	PSME4	SCN1B	PSME1	CER1	PSME2	EPHB4	SCN1A	EPHB3	PSMD10	EPHA5	PSMB11	EPHA4	PSMD12	EPHA7	PSMD11	EPHA6	PSMD14	PRKCQ	EPHA8	PSMD13	NOTCH1	FOXH1	HFE2	PSMB10	HNF1B	PSMA7	HNF1A	STX1B	RELA	LYN	PSMA8	SHTN1	PSMB6	KCNQ2	PSMB7	KCNQ3	PSMB4	EPHA1	PSMB5	STX1A	PSMB2	EPHA3	PSMB3	EPHA2	PSMB1	PAXIP1	PSMF1	EPHA10	EPAS1	SHFM1	PSMB8	SDC2	NFKB1	GSPT2	PSMB9	EVPL	KALRN	PSMC5	GSPT1	PSMC6	RRAS	PSMC3	SCN3B	PSMC4	PCK1	PSMC1	SCN3A	PSMC2	WWTR1	EGR2	KRTAP8-1	SMARCA4	MED13L	SNW1	SCN2A	SCN2B	NRP1	NRP2	HNF4G	GIT1	NCOA1	CAP1	NCOA2	FOXD3	NCOA6	NCOA3	RGMB	SREBF2	RGMA	ENAH	NR5A1	ARHGEF7	YAP1	RXRA	RELN	PERP	GPC1	PAK7	PAK6	PAK4	CAP2	CD72	KLK13	KLK14	KLK12	FOXA3	FOXA2	TGM1	CCND3	MPZ	SCN9A	ITGB1	TGM5	IL6R	SH3GL2	SPINK6	PIK3R3	SPINK5	ITGA5	PIK3R2	ADAM11	PIK3R1	POU3F1	POU3F2	PIK3CA	DOK1	TYROBP	AKT2	DOK4	AKT3	DOK5	SCN8A	DOK6	SPINK9	AKT1	KRTAP23-1	ARHGEF28	CACNA1D	FYN	CACNA1C	CACNA1H	DLG1	CACNA1G	DLG3	CACNA1I	DLG4	ADGRG6	LELP1	CACNA1S	GSK3B	KRTAP12-1	PRNP	CDK4	KRTAP12-3	KRTAP12-2	CNTN6	KRTAP12-4	MSN	CNTN2	TCF4	TCF3	LDB1	CHD9	TCHH	CREBBP	ZIC3	SCN5A	KRTAP10-1	CELA2A	PAK1	EED	DPPA4	RPS6KA5	MYOD1	PAK3	SCN4A	SCN4B	PAK2	KRTAP21-2	KRTAP21-3	LAMA2	LAMA1	CRMP1	HMGCR	ACVR1B	ACVR1C	TGS1	SLIT1	SCN7A	BNIP2	SLIT3	SLIT2	PDLIM7	KRTAP10-3	KRTAP10-2	KRTAP10-5	KRTAP10-4	KRTAP10-7	KRTAP10-6	KRTAP10-9	KRTAP10-8	ACVR2B	CFC1	ACVR2A	TCEB2	MAPK13	TCEB1	CARM1	KRTAP21-1	TRIO	LCE1A	LCE1B	ALCAM	SCN11A	MYC	HOXA3	HOXA2	HOXA1	PRSS8	HOXA4	MED1	KRTAP17-1	MED8	MED9	MED4	LCE1E	SOX10	LCE1F	MED6	LCE1C	MED7	LCE1D	LCE2B	LCE2C	SCN10A	LCE2A	KRTAP4-11	HOXB4	HOXB3	HOXB2	HOXB1	HOXD1	PRDM14	FLRT3	ZSCAN10	HOXC4	NKX2-2	CDK19	ST14	RDX	UPF3A	HOXD4	COL4A2	HOXD3	DAND5	COL4A1	RARG	COL6A2	KRTAP26-1	COL4A4	CLTB	ASH2L	HIF3A	COL4A3	LCE5A	CHL1	COL6A1	KRTAP1-5	KRTAP1-4	KRTAP1-3	TEAD1	KRTAP1-1	COL6A3	KRTAP15-1	COL4A5	TCF12	PAX4	COL6A6	PAX6	COL6A5	NCOR2	NCOR1	TAL1	LCE6A	RARA	RARB	SLC2A2	PLIN1	IVL	CAPNS1	LCE2D	LCE3C	LCE3D	LCE3A	LCE3B	FARP2	PCGF2	LCE3E	GCK	CAPN1	LCE4A	ZNF335	SEMA5A	CSF3R	PLXND1	TNF	CDH4	ADAM10	SALL1	CDH2	SALL4	CFL1	GRB10	KRTAP3-3	KRTAP3-2	PLXNC1	KRTAP3-1	RPTN	SEMA6A	PSEN1	SEMA6D	CACNB1	CACNB2	CACNB3	CACNB4	SEMA7A	NCSTN	CBFB	CUL2	NEUROD1	PLXNA2	ABL2	PLXNA1	COL9A1	SRGAP3	COL9A3	PI3	COL9A2	NKX6-1	SRGAP1	PLXNA4	PLXNA3	LAMC1	MAFA	CDK8	CNOT6	MAFB	DAB1	LHX3	LHX2	ITGA10	PLXNB3	LHX4	LHX9	TREM2	PAGR1	KRTAP5-3	WDR5	KRTAP5-2	KRTAP5-1	TRPC7	TRPC5	KRTAP5-9	TRPC6	KRTAP5-8	TRPC3	MMP2	KRTAP5-7	TRPC4	KRTAP5-6	MMP9	TRPC1	KRTAP5-5	KRTAP5-4	KRTAP19-2	KRTAP19-1	KRTAP19-4	KRTAP19-3	KRTAP19-6	KRTAP19-5	KRTAP19-8	KRTAP19-7	TFDP1	TFDP2	EVL	SOS2	CEBPA	SMARCD3	FURIN	HDAC3	CEBPD	CEBPE	SEMA3A	SEMA3E	CACNG8	ABLIM1	LAMB1	ABLIM2	ABLIM3	RBBP5	CACNG2	CACNG3	CACNG4	SPAG9	SEMA4A	CYP51A1	KLF4	NFASC	KLF5	LEP	INSM1	GFI1	PITPNA	RPS6KA4	SOX2	DAG1	CDON	KRT4	KRT3	KRT2	KRT1	EBF1	KRT8	KRT7	KRT5	KRT9	RUNX1	TIAM1	KRTAP20-1	EZR	PFN1	KRTAP20-2	PFN2	SPRR2E	SPRR2F	SPRR2G	KRTAP10-10	KRTAP10-11	KRTAP10-12	KLK5	PPL	KLK8	MYL12A	KRT33B	HELZ2	KRT33A	SPRR2A	SPRR2B	SPRR2D	VASP	CDSN	SIAH2	SIAH1	GDF1	SPRR1A	TDGF1	NODAL	SPRR1B	ROBO2	
EVASION OF ONCOGENE INDUCED SENESCENCE DUE TO DEFECTIVE P16INK4A BINDING TO CDK4%REACTOME DATABASE ID RELEASE 74%9630791	Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4	CDKN2A	CDK4	
RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING%REACTOME DATABASE ID RELEASE 74%8939245	RUNX1 regulates transcription of genes involved in BCR signaling	CBFB	BLK	ELF1	ELF2	PAX5	RUNX1	
ERK MAPK TARGETS%REACTOME%R-HSA-198753.1	ERK MAPK targets	RPS6KA1	MEF2C	MAPK3	PPP2CA	PPP2CB	VRK3	MAPK1	DUSP4	PPP2R1A	MAPK14	MAPK11	PPP2R5D	DUSP6	DUSP7	PPP2R1B	ELK1	RPS6KA3	RPS6KA5	MEF2A	DUSP3	MAPK7	RPS6KA2	
CATECHOLAMINE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%209905	Catecholamine biosynthesis	DBH	PNMT	DDC	TH	
DEFECTIVE CYP1B1 CAUSES GLAUCOMA%REACTOME%R-HSA-5579000.1	Defective CYP1B1 causes Glaucoma	CYP1B1	
ASSEMBLY OF VIRAL COMPONENTS AT THE BUDDING SITE%REACTOME%R-HSA-168316.3	Assembly of Viral Components at the Budding Site	CALR	CANX	
ADRENALINE SIGNALLING THROUGH ALPHA-2 ADRENERGIC RECEPTOR%REACTOME%R-HSA-392023.1	Adrenaline signalling through Alpha-2 adrenergic receptor	ADRA2C	ADRA2A	
COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES%REACTOME DATABASE ID RELEASE 74%1650814	Collagen biosynthesis and modifying enzymes	BMP1	COL9A1	COL9A3	COL9A2	COL18A1	COL14A1	COLGALT2	PLOD3	PLOD2	PLOD1	ADAMTS2	ADAMTS3	COLGALT1	P3H2	P3H1	PCOLCE	P3H3	PPIB	PCOLCE2	ADAMTS14	SERPINH1	CRTAP	COL25A1	P4HA1	P4HA2	P4HA3	COL15A1	COL19A1	COL11A1	COL11A2	COL26A1	COL10A1	COL28A1	COL27A1	COL24A1	COL22A1	COL1A1	COL3A1	COL1A2	COL2A1	TLL2	COL4A2	TLL1	COL5A1	COL4A1	COL6A2	COL4A4	COL7A1	COL5A3	COL4A3	COL5A2	COL6A1	P4HB	COL20A1	COL8A2	COL4A6	COL21A1	COL6A3	COL4A5	COL8A1	COL6A6	COL6A5	COL16A1	COL12A1	COL23A1	COL17A1	COL13A1	
KERATAN SULFATE DEGRADATION%REACTOME DATABASE ID RELEASE 74%2022857	Keratan sulfate degradation	GLB1L	LUM	GLB1	OGN	OMD	HEXB	PRELP	KERA	HEXA	FMOD	GNS	
LGI-ADAM INTERACTIONS%REACTOME%R-HSA-5682910.2	LGI-ADAM interactions	CACNG8	CACNG2	CACNG3	CACNG4	DLG4	LGI1	LGI4	LGI3	LGI2	STX1B	ADAM22	ADAM11	ADAM23	STX1A	
RESOLUTION OF SISTER CHROMATID COHESION%REACTOME DATABASE ID RELEASE 74%2500257	Resolution of Sister Chromatid Cohesion	RCC2	DYNC1LI1	NDC80	DYNLL1	ZWINT	DYNC1LI2	STAG1	CKAP5	STAG2	AHCTF1	ZW10	SGOL2	SGOL1	NUF2	WAPAL	MAPRE1	SPDL1	SEC13	NDEL1	NUP133	NUDC	RANGAP1	SMC1A	PAFAH1B1	INCENP	BIRC5	DYNC1I2	ITGB3BP	MIS12	CENPA	AURKB	NSL1	CCNB2	CENPC	CCNB1	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	KIF18A	PPP2CA	CENPN	CLASP1	CENPO	PPP2CB	B9D2	CENPP	DYNC1H1	CENPQ	NUP43	SPC24	SPC25	RANBP2	NDE1	PLK1	CLIP1	CDK1	NUP37	PPP1CC	DYNLL2	KIF2A	KIF2C	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	CLASP2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	DYNC1I1	CENPE	RPS27	XPO1	NUP107	PPP2R1B	NUP160	NUP85	PPP2R1A	ERCC6L	ZWILCH	CASC5	SMC3	KNTC1	MAD1L1	CDCA5	CDCA8	PDS5B	PDS5A	PMF1	SKA1	SKA2	DSN1	RAD21	
APOPTOTIC FACTOR-MEDIATED RESPONSE%REACTOME%R-HSA-111471.4	Apoptotic factor-mediated response	MAPK3	C1QBP	CDKN2A	MAPK1	BAX	CYCS	AVEN	APAF1	DIABLO	CARD8	APIP	XIAP	UACA	CASP9	CASP3	CASP7	BAK1	
TGF-BETA RECEPTOR SIGNALING ACTIVATES SMADS%REACTOME DATABASE ID RELEASE 74%2173789	TGF-beta receptor signaling activates SMADs	NEDD8	PPP1R15A	USP15	UBA52	NEDD4L	MTMR4	SMAD4	PMEPA1	SMAD2	SMURF2	CBL	SMAD3	SMURF1	TGFB1	UCHL5	TGFBR1	PPP1CA	XPO1	SMAD7	TGFBR2	BAMBI	STRAP	STUB1	UBB	UBE2M	FKBP1A	UBC	RPS27A	PPP1CB	PPP1CC	FURIN	
INHIBITION OF INTERFERON SYNTHESIS%REACTOME DATABASE ID RELEASE 74%168305	Inhibition of Interferon Synthesis	
DEFECTIVE GALNT3 CAUSES FAMILIAL HYPERPHOSPHATEMIC TUMORAL CALCINOSIS (HFTC)%REACTOME DATABASE ID RELEASE 74%5083625	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)	MUC3A	MUC5AC	MUC1	MUC7	MUC12	MUC13	MUC15	MUC20	MUC4	MUC21	MUC6	GALNT3	MUCL1	MUC17	MUC5B	
DOWNSTREAM SIGNALING OF ACTIVATED FGFR1%REACTOME%R-HSA-5654687.2	Downstream signaling of activated FGFR1	FLRT3	PTPN11	FRS2	FGF20	FRS3	FGF1	FGF23	FGF2	FGF22	FGF3	GAB1	FGF4	FGF6	NRAS	FGF9	PLCG1	SOS1	HRAS	PIK3R1	PIK3CA	FLRT2	FGF10	FLRT1	
REGULATION OF RUNX1 EXPRESSION AND ACTIVITY%REACTOME%R-HSA-8934593.1	Regulation of RUNX1 Expression and Activity	PML	CCND2	CBFB	CDK6	SRC	PTPN11	TNRC6C	MOV10	CCND1	AGO3	AGO4	AGO1	CCND3	AGO2	TNRC6A	TNRC6B	RUNX1	
SYNTHESIS OF PS%REACTOME DATABASE ID RELEASE 74%1483101	Synthesis of PS	PTDSS2	PTDSS1	
FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS%REACTOME%R-HSA-444473.1	Formyl peptide receptors bind formyl peptides and many other ligands	SAA1	HEBP1	ANXA1	APP	FPR1	FPR3	FPR2	
TICAM1,TRAF6-DEPENDENT INDUCTION OF TAK1 COMPLEX%REACTOME DATABASE ID RELEASE 74%9014325	TICAM1,TRAF6-dependent induction of TAK1 complex	RPS27A	TLR3	TICAM1	UBB	TAB3	TAB2	TAB1	TRAF6	UBC	UBA52	MAP3K7	
ELECTRON TRANSPORT FROM NADPH TO FERREDOXIN%REACTOME DATABASE ID RELEASE 74%2395516	Electron transport from NADPH to Ferredoxin	FDX1	FDXR	FDX1L	
TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES%REACTOME DATABASE ID RELEASE 74%6791312	TP53 Regulates Transcription of Cell Cycle Genes	CDKN1A	RQCD1	CDKN1B	ZNF385A	PCBP4	BTG2	TNKS1BP1	CNOT6L	PRMT1	CCNA2	CDC25C	CCNA1	RBL2	CCNE2	RBL1	CCNE1	PLAGL1	CNOT6	E2F4	E2F7	AURKA	E2F8	PLK3	CCNB1	NPM1	GADD45A	ARID3A	CNOT10	CNOT4	CNOT7	RGCC	CARM1	CNOT1	CNOT11	CNOT2	CNOT3	CNOT8	CDK2	CENPJ	CDK1	TFDP1	TFDP2	BAX	PLK2	SFN	PCNA	EP300	E2F1	TP53	
IMATINIB-RESISTANT PDGFR MUTANTS%REACTOME%R-HSA-9674396.1	Imatinib-resistant PDGFR mutants	PDGFRA	
RNA POLYMERASE I TRANSCRIPTION TERMINATION%REACTOME DATABASE ID RELEASE 74%73863	RNA Polymerase I Transcription Termination	CCNH	TTF1	TAF1D	ZNRD1	TAF1B	TAF1C	POLR2E	TWISTNB	POLR2F	TBP	TAF1A	UBTF	PTRF	POLR2H	POLR2K	CD3EAP	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	POLR1C	CDK7	ERCC3	POLR1A	POLR1B	ERCC2	POLR1E	MNAT1	
DEATH RECEPTOR SIGNALLING%REACTOME%R-HSA-73887.4	Death Receptor Signalling	SQSTM1	NSMAF	RIPK2	ARHGEF26	MAGED1	RTN4	ABR	BCL2L11	SHARPIN	NGEF	ECT2	ARHGEF33	NGFR	ARHGEF35	UBA52	ARHGEF37	ARHGEF39	ARHGEF38	GNB2L1	TNFRSF10D	NET1	ITGB3BP	CYLD	TNFAIP3	BIRC2	OTUD7B	ARHGEF10L	AATF	BIRC3	SMPD3	UBB	SMPD2	AKAP13	CASP10	MCF2L	UBC	CASP2	ARHGEF10	PLEKHG2	MAPK8	TRIO	ARHGEF15	PLEKHG5	RPS27A	ARHGEF17	ARHGEF16	ARHGEF19	ARHGEF18	TRAF1	NGF	TNFRSF1A	ARHGEF9	TAX1BP1	ARHGEF3	ARHGEF4	RAC1	ARHGEF1	ARHGEF2	ARHGEF5	ARHGEF6	VAV1	RNF31	FGD1	FGD2	GNA13	FGD3	HDAC2	FGD4	HDAC1	LINGO1	USP21	XIAP	MCF2	CFLAR	OTULIN	ARHGEF11	ARHGEF12	MAG	RHOA	BAD	RASGRF2	BAG4	TNF	IKBKB	ADAM17	IKBKG	MAP3K7	PSEN1	CHUK	NCSTN	TRAF6	RELA	SOS1	TAB3	TAB2	TAB1	CASP3	NFKB1	KALRN	NFKBIA	VAV3	SOS2	VAV2	HDAC3	TRADD	ARHGEF7	TNFRSF10B	TRAF2	TNFRSF10A	FASLG	CASP8	TNFSF10	FAS	RIPK1	FADD	YWHAE	TIAM1	IRAK1	PRDM4	SPPL2B	PSEN2	SPPL2A	PREX1	MYD88	ARHGDIA	ARHGEF40	APH1A	ITSN1	PRKCI	USP4	APH1B	USP2	OMG	CLIP3	TIAM2	NGFRAP1	OBSCN	PSENEN	RBCK1	
PROCESSING OF SMDT1%REACTOME%R-HSA-8949664.1	Processing of SMDT1	PHB	STOML2	CCDC109B	SPG7	PHB2	PARL	AFG3L2	C2orf47	SMDT1	PMPCB	YME1L1	PMPCA	MICU3	MICU2	MICU1	MCU	
TANDEM PORE DOMAIN HALOTHANE-INHIBITED K+ CHANNEL (THIK)%REACTOME DATABASE ID RELEASE 74%1299287	Tandem pore domain halothane-inhibited K+ channel (THIK)	KCNK13	
RNA POLYMERASE II TRANSCRIPTION INITIATION AND PROMOTER CLEARANCE%REACTOME%R-HSA-76042.3	RNA Polymerase II Transcription Initiation And Promoter Clearance	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	CCNH	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	TBP	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	GTF2A1	CDK7	GTF2A2	GTF2B	ERCC3	TAF9	TAF1L	AK6	ERCC2	GTF2E1	GTF2E2	TAF7L	MNAT1	TAF9B	TAF15	TAF12	TAF13	TAF10	
CRISTAE FORMATION%REACTOME DATABASE ID RELEASE 74%8949613	Cristae formation	MTX2	DNAJC11	IMMT	ATP5F1	MT-ATP8	ATP5J2	TMEM11	ATP5S	ATP5A1	ATP5C1	ATP5J	ATP5I	ATP5H	ATP5G3	ATP5G2	ATP5O	ATP5G1	ATP5L	MT-ATP6	APOO	ATP5B	SAMM50	CHCHD3	MINOS1	ATP5E	CHCHD6	ATP5D	HSPA9	APOOL	MTX1	C19orf70	
THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS (PARS)%REACTOME DATABASE ID RELEASE 74%456926	Thrombin signalling through proteinase activated receptors (PARs)	MAPK3	GNG12	GNG11	GNG13	GNA14	GNB2	GNA15	GNA11	GNB1	GNA12	GNAQ	GNB4	GNB3	F2RL2	F2RL3	GNB5	GNGT1	ARRB1	GNGT2	ARRB2	MAPK1	F2R	F2	GNG3	GNA13	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	
ACTIVATION OF TRKA RECEPTORS%REACTOME%R-HSA-187015.2	Activation of TRKA receptors	ADCYAP1	NGF	NTRK1	ADORA2A	ADCYAP1R1	NTRK2	
XENOBIOTICS%REACTOME DATABASE ID RELEASE 74%211981	Xenobiotics	ARNT	CYP2C9	CYP2A7	CYP2A6	CYP2C8	CYP2W1	CYP2S1	CYP1A2	CYP1A1	AHRR	CYP2E1	AHR	CYP2C19	CYP3A4	CYP2C18	CYP3A5	CYP3A7	CYP2B6	CYP2A13	CYP2D6	CYP2F1	CYP2J2	ARNT2	CYP3A7-CYP3A51P	CYP3A43	
DISEASES OF PROGRAMMED CELL DEATH%REACTOME%R-HSA-9645723.3	Diseases of programmed cell death	TRAF2	LMNB1	FASLG	CASP8	BCL2L11	CDC25A	RIPK1	FADD	CDC25C	PRDX2	PRDX1	SOD2	CDC25B	CDK5	APP	YWHAE	C1QBP	CAPNS1	FOXO3	CDKN2A	CAPNS2	CAPN2	CAPN1	CAST	CDK5R1	JUN	GOLGA2	TRADD	
SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE%REACTOME DATABASE ID RELEASE 74%1660517	Synthesis of PIPs at the late endosome membrane	PIK3R4	MTMR9	PIK3C2A	MTM1	MTMR7	PIK3C3	FIG4	VAC14	MTMR2	MTMR4	PIKFYVE	
HDR THROUGH SINGLE STRAND ANNEALING (SSA)%REACTOME DATABASE ID RELEASE 74%5685938	HDR through Single Strand Annealing (SSA)	RAD17	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	ABL1	KAT5	ATM	BRCA1	NBN	TOP3A	BLM	RFC5	RFC3	RBBP8	RPA1	RFC4	RPA2	MRE11A	RFC2	RAD50	RAD51	RPA3	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	WRN	RMI1	HUS1	RAD52	ERCC4	ERCC1	
VIRION ASSEMBLY AND RELEASE%REACTOME DATABASE ID RELEASE 74%9694322	Virion Assembly and Release	
DEFECTIVE SLC22A18 CAUSES LUNG CANCER (LNCR) AND EMBRYONAL RHABDOMYOSARCOMA 1 (RMSE1)%REACTOME%R-HSA-5619066.1	Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1)	SLC22A18	
LEISHMANIA INFECTION%REACTOME%R-HSA-9658195.2	Leishmania infection	PRKAR2B	MAPK8	MAPK1	VAV1	PLCG2	GLP1R	VIPR1	VIPR2	SCT	ADM	PTH1R	CYSLTR2	IL10	IL6	GLP2R	CD163	PLK2	PTH2R	RHBDF2	GIP	ADCYAP1	CRH	IAPP	HSP90AB1	CALCA	RAMP2	ADCYAP1R1	RAMP3	CALCRL	CALCB	GIPR	PTH	PTH2	PTHLH	CRHR1	GHRHR	CALCR	FZD7	SCTR	IGKV2-28	IGKV1-12	IGKV3D-20	GCG	IGKV2D-28	ADM2	GHRH	IGKV4-1	VIP	RAMP1	IGKV2D-30	RELA	IGKV3-11	LYN	IGKV5-2	NFKB1	CYFIP2	NCKAP1	CYFIP1	MAPK14	WIPF1	ARPC1B	WIPF2	ARPC1A	WIPF3	BRK1	WASL	ACTB	ACTG1	NCK1	ACTR3	VAV3	ACTR2	VAV2	MYH2	ELMO1	BTK	ELMO2	WAS	NCKIPSD	NCKAP1L	WASF1	WASF2	WASF3	MYO10	MYO5A	ARPC4	MYO9B	ARPC5	BAIAP2	MYO1C	ABI2	ARPC2	ARPC3	ABI1	AVP	ADORA2A	PRKACG	PRKACB	GNGT1	GNGT2	ADCY9	PRKAR1B	FYN	PRKAR1A	WNT5A	PRKAR2A	ITPR1	ITPR2	ITPR3	GNAS	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	PTK2	GNG8	ADCY4	ADCY3	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	CREB1	ADCY5	GNG12	GNG11	GNG13	ABL1	GNB2	GNB1	GNB4	GNB3	GNB5	HCK	RAC1	DOCK1	CDC42	MYH9	SYK	CRK	ADAM17	MAPK3	PLCG1	RXFP1	ADRB1	RXFP2	GPR176	ADRB2	GNAT3	HTR4	C3AR1	CTSG	PTGDR	ENTPD1	HTR6	ENTPD5	HTR7	TXNIP	LHB	TXN	HRH2	MEFV	CRHR2	DRD1	MC2R	CGA	AHCYL1	GPR15	MC1R	CD3G	DRD5	TAAR8	NOX1	PRKX	GPR27	FCGR3A	TAAR9	GPR25	FCGR1A	YES1	GPR20	TAAR6	MC4R	FGR	GPR39	FCGR2A	FSHB	GPR32	TAAR5	IL18	TAAR2	GPBAR1	MC3R	IL1A	TAAR1	IL1B	FSHR	NPSR1	ADRB3	PTGER4	GPR45	PTGER2	FURIN	GNAI3	NOXO1	GNAI1	GNAI2	NPS	NT5E	GPR150	GPHA2	P2RY11	MC5R	GPHB5	PYCARD	CYSLTR1	GGT1	LHCGR	CYBA	DPEP2	DPEP1	DPEP3	GNAZ	GPR83	GPR84	C3	DVL1	DVL2	IGHG4	NLRP3	DVL3	IGHG1	GGT5	IGHG2	NOXA1	RLN2	RLN3	PSTPIP1	CASP1	INSL3	TSHB	PTGIR	AVPR2	ADORA2B	TSHR	P2RX7	POMC	P2RX4	SUGT1	PRKACA	JUN	NFKB2	
TRANSCRIPTIONAL REGULATION BY TP53%REACTOME%R-HSA-3700989.6	Transcriptional Regulation by TP53	SETD8	FOS	UBA52	CCNA2	CCNA1	CCNE2	TNFRSF10D	CCNE1	AURKA	CCNB1	UBB	CASP10	UBC	CASP2	BRCA1	RPS27A	NBN	TOP3A	PPP2CA	PPP2CB	BLM	RBBP8	RPA1	RPA2	MRE11A	CDK2	MLH1	CENPJ	CDK5R1	CDK1	RAD50	RPA3	MDC1	CCNK	TP53RK	EHMT1	NOC2L	GLS	TP53AIP1	PIP4K2A	MT-CO1	PIP4K2B	PIP4K2C	TP63	TACO1	DAXX	DDIT4	COX6A1	L3MBTL1	MEAF6	NUAK1	TP53BP2	COX6B1	COX7A2L	BANP	SCO1	PRELID1	SCO2	CRADD	TPX2	MT-CO2	CDK12	CDK13	MT-CO3	TP73	SETD9	CHM	COX19	BBC3	COX16	ING5	POLR2A	ING2	POLR2B	AIFM2	POLR2C	PRMT5	COX18	BRD1	POLR2D	DDB2	COX11	RAD51D	COX14	POLR2E	PLK2	SGK1	POLR2F	PMS2	BRD7	POLR2G	TIGAR	POLR2H	HIPK1	POLR2I	SURF1	POU4F1	POLR2J	POU4F2	HIPK2	POLR2K	TTC5	POLR2L	CCNG1	CCNT2	PRDM1	SESN3	CYCS	SESN2	BNIP3L	USP7	G6PD	COX20	COX7B	IGFBP3	MSH2	COX4I1	FANCD2	TAF9	KAT6A	TAF1L	MAPKAPK5	AK6	COX7C	NDRG1	SMYD2	TAF7L	COX8A	PMAIP1	TAF9B	BCL2L14	ZNF420	TAF15	FANCI	E2F1	TAF12	BRPF1	TAF13	SLMO1	TAF10	BRPF3	TAF11	TNFRSF10C	TAF4B	FANCC	RQCD1	TAF7	TP53I3	TAF6	BCL6	TAF5	JMY	TAF4	PIN1	TAF3	PPP1R13B	TAF2	DYRK2	TAF1	PTEN	TRIAP1	PIDD1	CASP6	PPP1R13L	GPX2	RABGGTB	RABGGTA	YWHAB	RRM2B	TMEM219	TMEM55B	COX5B	RNF34	COX5A	GLS2	NLRC4	TP53INP1	RFFL	YWHAZ	TXNRD1	NDUFA4	COX6C	LRPPRC	MAPK14	MAPK11	TNFRSF10B	CSNK2A1	PERP	TNFRSF10A	CSNK2A2	FAS	BAX	NELFB	CSNK2B	PRR5	PDPK1	MAPKAP1	MTOR	AKT2	AKT3	MLST8	AKT1	RICTOR	STEAP3	CREBBP	EP300	TP53	TNRC6C	MOV10	AGO3	AGO4	AGO1	PRDX2	BIRC5	PRDX1	AGO2	CDK5	AURKB	TNRC6A	CTDP1	TNRC6B	ELL	CCNT1	SUPT4H1	TCEB3	TCEB2	TCEB1	CARM1	NELFA	NELFCD	TCEB3C	TCEB3CL	TCEB3B	NELFE	SUPT16H	SSRP1	SUPT5H	CDK9	TCEA1	TCEB3CL2	GPI	APAF1	BRIP1	HDAC2	EXO1	HDAC1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	RAD17	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	PRKAA1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	RPTOR	STK11	ATM	SLC38A9	PRKAB2	TSC2	TSC1	PRKAB1	RRAGA	RRAGC	RRAGB	RHEB	YWHAQ	PML	RRAGD	SFN	BID	LAMTOR2	CDKN2A	LAMTOR1	YWHAH	LAMTOR4	RFC5	LAMTOR3	RFC3	LAMTOR5	PCNA	RFC4	RFC2	PPP2R5C	CDKN1A	CDKN1B	PHF20	CHEK2	CHEK1	ZNF385A	PCBP4	MDM2	BTG2	MDM4	TNKS1BP1	CNOT6L	PRMT1	CDC25C	RBL2	RBL1	PLAGL1	CNOT6	E2F4	E2F7	E2F8	PLK3	NPM1	GADD45A	ARID3A	CNOT10	CNOT4	CNOT7	RGCC	CNOT1	CNOT11	CNOT2	CNOT3	CNOT8	TBP	TXN	GTF2F1	GTF2F2	TFDP1	TFDP2	PPP2R1B	KAT5	CCNH	EHMT2	CHD4	CHD3	ATF2	CASP1	YWHAE	RBBP4	RBBP7	MTA2	PPP2R1A	MBD3	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GATAD2B	GTF2H5	YWHAG	GATAD2A	MAP2K6	JUN	CDK7	ERCC3	ERCC2	USP2	MNAT1	
REGULATION OF BETA-CELL DEVELOPMENT%REACTOME%R-HSA-186712.2	Regulation of beta-cell development	PTF1A	NKX2-2	FOXO1	NEUROD1	RFX6	MAML3	MAMLD1	INS	NKX6-1	FOXA3	FOXA2	NOTCH1	INSM1	MAFA	HNF1B	HNF1A	PAX4	PAX6	AKT2	FGF10	AKT3	SLC2A2	AKT1	IAPP	ONECUT3	ONECUT1	GCK	PDX1	SNW1	NEUROG3	MAML2	MAML1	KAT2B	HNF4G	RBPJ	KAT2A	CREBBP	EP300	HES1	
CELLULAR RESPONSE TO HEAT STRESS%REACTOME DATABASE ID RELEASE 74%3371556	Cellular response to heat stress	MAPK3	CAMK2G	NUP62	NDC1	SEC13	NUP133	VCP	NUP50	NUP54	MAPKAPK2	MAPK1	EEF1A1	NUP43	RAE1	RANBP2	RPA1	HSPA8	RPA2	NUP35	NUPL2	NUP37	RPA3	NUP107	NUP188	HSPB8	CCAR2	HSBP1	HSPA9	SIRT1	DNAJC2	DNAJC7	NUP214	FKBP4	NUP210	CRYAB	RPS19BP1	HSPA4L	HSPA14	ATR	HSPA13	HDAC6	DNAJB1	NUP93	BAG5	HSPA5	C11orf73	HSPH1	BAG2	DNAJB6	BAG3	BAG1	HSF1	HSPA1L	RPTOR	ST13	HSPA4	PTGES3	ATM	HSPA6	HSPA2	NUP205	HSPA12A	POM121	HSPA12B	MTOR	AAAS	NUP160	YWHAE	MLST8	NUP85	TPR	AKT1S1	NUP88	HSP90AB1	GSK3B	CAMK2A	NUP155	BAG4	NUP153	HSP90AA1	CREBBP	EP300	CAMK2B	CAMK2D	
SYNTHESIS OF 5-EICOSATETRAENOIC ACIDS%REACTOME DATABASE ID RELEASE 74%2142688	Synthesis of 5-eicosatetraenoic acids	GPX1	GPX4	PON2	ALOX5AP	PON1	LTC4S	GPX2	PON3	ALOX5	
EPH-EPHRIN MEDIATED REPULSION OF CELLS%REACTOME DATABASE ID RELEASE 74%3928665	EPH-ephrin mediated repulsion of cells	NCSTN	EPHB2	EPHB1	DNM1	EFNA5	EFNA4	EPHB4	EFNB2	EPHB3	EPHA5	EFNB1	EPHA4	EFNB3	EPHA7	AP2B1	CLTB	EPHA6	EPHA8	EFNA1	EFNA3	EFNA2	LYN	EPHA1	CLTCL1	EPHA3	EPHA2	AP2A1	EPHA10	AP2A2	TIAM1	FYN	AP2M1	MMP2	MMP9	CLTC	CLTA	RAC1	YES1	PSEN2	ADAM10	APH1A	APH1B	VAV3	VAV2	PSEN1	PSENEN	AP2S1	
LOSS OF FUNCTION OF SMAD4 IN CANCER%REACTOME%R-HSA-3304347.1	Loss of Function of SMAD4 in Cancer	SMAD2	SMAD3	SMAD4	
REGULATION OF PTEN STABILITY AND ACTIVITY%REACTOME%R-HSA-8948751.1	Regulation of PTEN stability and activity	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PTEN	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	TNKS2	TNKS	XIAP	CSNK2A1	CSNK2A2	CSNK2B	STUB1	AKT2	AKT3	AKT1	PREX2	TRIM27	USP13	PSMD8	WWP2	RNF146	PSMD9	NEDD4	PSMD6	MKRN1	PSMD7	FRK	PSMD4	OTUD3	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS%REACTOME%R-HSA-442755.6	Activation of NMDA receptors and postsynaptic events	RPS6KA1	ADCY1	MAPK3	ADCY8	NEFL	CREB1	CAMK2G	KIF17	NRGN	CASK	GRIA1	GRIA2	LIN7A	NRAS	LIN7C	PPM1E	LIN7B	HRAS	PPM1F	CAMKK1	CAMKK2	GRIN2A	LRRC7	PRKAR2B	GRIA3	GRIA4	GRIN2C	GRIN3B	GRIN3A	KPNA2	NBEA	CAMK4	APBA1	CAMK1	GRIN1	MAPK1	PRKX	RAC1	GIT1	SRC	PRKAA1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	PDPK1	DLG2	PRKAB2	PRKAB1	PRKACG	PRKACB	RASGRF2	RASGRF1	PRKAR1B	DLG1	PRKAR1A	DLG3	ACTN2	DLG4	PRKACA	CAMK2A	PRKAR2A	NRG1	GRIN2B	GRIN2D	RPS6KA3	CAMK2B	RPS6KA6	CAMK2D	RPS6KA2	
DEFECTIVE B3GAT3 CAUSES JDSSDHD%REACTOME%R-HSA-3560801.1	Defective B3GAT3 causes JDSSDHD	AGRN	GPC1	NCAN	BGN	VCAN	DCN	SDC4	CSPG5	B3GAT3	CSPG4	SDC3	GPC3	SDC1	GPC2	GPC5	HSPG2	GPC4	BCAN	GPC6	SDC2	
APC C:CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C:CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1%REACTOME DATABASE ID RELEASE 74%174178	APC C:Cdh1 mediated degradation of Cdc20 and other APC C:Cdh1 targeted proteins in late mitosis early G1	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	SKP2	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	ANAPC4	AURKB	PSMA8	AURKA	ANAPC5	PSMB6	PSMB7	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	FZR1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	PSMC2	UBE2S	PLK1	CDC16	RB1	PTTG1	CDC20	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
SIGNALING BY BRAF AND RAF FUSIONS%REACTOME%R-HSA-6802952.1	Signaling by BRAF and RAF fusions	RAF1	MAPK3	CSK	CAMK2G	BCL2L11	AKAP9	YWHAB	LMNA	NRAS	CNKSR2	HRAS	APBB1IP	CNKSR1	AGK	MAPK1	ITGA2B	PEBP1	JAK2	MAP2K1	MAP2K2	VCL	SRC	RAP1B	KIAA1549	RAP1A	MPRIP	AGTRAP	MARK3	AP3B1	SND1	PAPD7	ESRP1	KDM7A	FAM114A2	ZC3HAV1	TRAK1	PAPSS1	FXR1	FN1	ATG7	QKI	CLCN6	FAM131B	AGGF1	ITGB3	ARRB1	ARAF	ARRB2	FGB	FGA	TRIM24	VWF	CAMK2A	KSR1	FGG	TLN1	KSR2	IQGAP1	BRAF	CAMK2B	CAMK2D	
FCERI MEDIATED MAPK ACTIVATION%REACTOME DATABASE ID RELEASE 74%2871796	FCERI mediated MAPK activation	MAPK3	PAK2	FOS	IGKV2-28	IGKV1-12	IGKV3D-20	IGKV2D-28	IGKV4-1	IGHE	IGKV2D-30	NRAS	IGKV3-11	PLCG1	LYN	IGKV5-2	SOS1	HRAS	SYK	MAPK9	MAPK8	GRAP2	LCP2	MAP2K4	MAP3K1	MAPK10	MAPK1	RAC1	MAP2K7	VAV1	JUN	PLCG2	VAV3	VAV2	PAK1	
FRS-MEDIATED FGFR2 SIGNALING%REACTOME%R-HSA-5654700.3	FRS-mediated FGFR2 signaling	PTPN11	FRS2	FGF20	FRS3	FGF1	FGF23	FGF2	FGF22	FGF3	FGF4	FGF16	FGF6	NRAS	FGF7	FGF9	SOS1	HRAS	FGF18	FGF10	
RRNA PROCESSING IN THE NUCLEUS AND CYTOSOL%REACTOME DATABASE ID RELEASE 74%8868773	rRNA processing in the nucleus and cytosol	CSNK1E	NOP2	ISG20L2	EMG1	UTP20	NOP14	RPP40	RCL1	NOP10	RBM28	DDX49	DDX47	WDR3	UBA52	NOB1	PELP1	UTP15	DDX52	SENP3	UTP18	C1D	SKIV2L2	DDX21	BMS1	RPP14	DCAF13	NOP56	NOP58	KRR1	RPS27A	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	DIS3	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	EXOSC7	RPL13	EXOSC6	RPL15	EXOSC5	RPS2	EXOSC4	RPL18	EXOSC9	RPL17	EXOSC8	EXOSC3	EXOSC2	RPL19	EXOSC1	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	LTV1	RRP1	FCF1	THUMPD1	PWP2	RRP9	IMP3	WDR75	IMP4	CIRH1A	XRN2	RRP7A	PDCD11	ERI1	GAR1	WBSCR22	DHX37	PNO1	TBL3	LAS1L	MPHOSPH10	NOL11	NOL12	NAT10	WDR46	WDR43	TRMT112	RIOK2	RIOK1	UTP14A	UTP14C	WDR36	TEX10	DIEXF	GNL3	NHP2L1	NIP7	TSR3	HEATR1	NOL9	NOC4L	NOL6	EXOSC10	PES1	RRP36	UTP6	RIOK3	UTP3	WDR18	WDR12	BYSL	BOP1	TSR1	MPHOSPH6	RPP30	FBL	RPP38	DIMT1	UTP11L	FTSJ3	EBNA1BP2	DKC1	NCL	CSNK1D	NHP2	RPP21	RPP25	
FERTILIZATION%REACTOME%R-HSA-1187000.2	Fertilization	IZUMO4	IZUMO1	ADAM30	ACR	ADAM2	KCNU1	CATSPERB	CATSPERD	CATSPERG	CD9	ZP1	ZP3	ZP2	SPAM1	ZP4	CATSPER1	CATSPER3	CATSPER2	B4GALT1	CATSPER4	HVCN1	ADAM21	ADAM20	IZUMO3	OVGP1	IZUMO2	
MISMATCH REPAIR (MMR) DIRECTED BY MSH2:MSH6 (MUTSALPHA)%REACTOME%R-HSA-5358565.1	Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	PMS2	PCNA	RPA1	RPA2	LIG1	MLH1	POLD3	MSH6	POLD4	RPA3	POLD1	MSH2	EXO1	POLD2	
TRAF3 DEFICIENCY - HSE%REACTOME%R-HSA-5602571.2	TRAF3 deficiency - HSE	TLR3	TICAM1	TRAF3	
VXPX CARGO-TARGETING TO CILIUM%REACTOME DATABASE ID RELEASE 74%5620916	VxPx cargo-targeting to cilium	EXOC8	EXOC7	RAB3IP	ASAP1	PKD2	PKD1	ARF4	RAB11A	RHO	EXOC4	CNGA2	EXOC3	EXOC6	CNGA4	EXOC5	RAB8A	RAB11FIP3	EXOC2	EXOC1	CNGB1	GBF1	
DEFECTIVE SLC2A9 CAUSES HYPOURICEMIA RENAL 2 (RHUC2)%REACTOME%R-HSA-5619047.2	Defective SLC2A9 causes hypouricemia renal 2 (RHUC2)	SLC2A9	
MYD88 CASCADE INITIATED ON PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 74%975871	MyD88 cascade initiated on plasma membrane	RPS6KA1	RIPK2	MAPK3	IRAK4	FOS	CREB1	DUSP4	TRAF6	PELI1	UBA52	TLR10	UBE2V1	TLR5	DUSP6	DUSP7	CUL1	RELA	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	AGER	BTRC	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
CHYLOMICRON ASSEMBLY%REACTOME DATABASE ID RELEASE 74%8963888	Chylomicron assembly	APOE	P4HB	APOB	SAR1B	MTTP	APOA2	APOC3	APOA1	APOA4	APOC2	
AXIN MISSENSE MUTANTS DESTABILIZE THE DESTRUCTION COMPLEX%REACTOME DATABASE ID RELEASE 74%5467340	AXIN missense mutants destabilize the destruction complex	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	PPP2R1B	AMER1	AXIN1	APC	
RHO GTPASES ACTIVATE CIT%REACTOME DATABASE ID RELEASE 74%5625900	RHO GTPases activate CIT	KIF14	CIT	CDKN1B	PPP1CB	PRC1	PPP1R12B	DLG4	RHOC	RHOA	RAC1	MYL12B	RHOB	MYL6	MYH9	MYH14	MYH11	PPP1R12A	MYH10	MYL9	
SIGNALING BY FGFR2 IIIA TM%REACTOME%R-HSA-8851708.1	Signaling by FGFR2 IIIa TM	NCBP2	POLR2E	POLR2F	GTF2F1	GTF2F2	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	FGF1	FGF2	FGFR2	POLR2A	POLR2B	POLR2C	NCBP1	POLR2D	
G0 AND EARLY G1%REACTOME DATABASE ID RELEASE 74%1538133	G0 and Early G1	CDC25A	TOP2A	CCNA2	LIN54	CCNA1	LIN37	RBL2	CCNE2	MAX	RBL1	CCNE1	LIN9	MYBL2	E2F4	E2F5	LIN52	DYRK1A	RBBP4	MYC	CDC6	PCNA	CDK2	CDK1	TFDP1	HDAC1	TFDP2	E2F1	
RHO GTPASES ACTIVATE WASPS AND WAVES%REACTOME%R-HSA-5663213.1	RHO GTPases Activate WASPs and WAVEs	NCKIPSD	NCKAP1L	MAPK3	WASF1	WASF2	WASF3	ARPC4	ARPC5	BAIAP2	ABL1	ABI2	ARPC2	ARPC3	ABI1	MAPK1	CYFIP2	NCKAP1	CYFIP1	RAC1	WIPF1	ARPC1B	WIPF2	ARPC1A	WIPF3	BRK1	WASL	ACTB	ACTG1	NCK1	ACTR3	CDC42	ACTR2	PTK2	BTK	WAS	
CREATINE METABOLISM%REACTOME%R-HSA-71288.1	Creatine metabolism	CKMT2	SLC6A7	GATM	SLC6A8	CKM	CKMT1A	CKMT1B	CKB	SLC6A12	SLC6A11	GAMT	
TRANSCRIPTIONAL REGULATION BY THE AP-2 (TFAP2) FAMILY OF TRANSCRIPTION FACTORS%REACTOME DATABASE ID RELEASE 74%8864260	Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	NOP2	TFAP2D	APOE	TFAP2E	CDKN1A	CITED1	CITED2	CITED4	YEATS4	YY1	ERBB2	EGFR	MYBL2	NPM1	KIT	MYC	CGA	VEGFA	DEK	KDM5B	TGFA	HSPD1	SUMO1	PITX2	UBE2I	ATAD2	KCTD1	ESR1	CREBBP	KCTD15	EP300	TFAP2A	TFAP2B	WWOX	TFAP2C	
PRE-NOTCH TRANSCRIPTION AND TRANSLATION%REACTOME%R-HSA-1912408.4	Pre-NOTCH Transcription and Translation	HIST2H2AC	H2AFJ	MAML3	MAMLD1	TNRC6C	MOV10	H2AFZ	AGO3	H2AFX	AGO4	H2AFV	NOTCH1	AGO1	HIST2H2BE	AGO2	HIST4H4	TNRC6A	TNRC6B	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	SNW1	TFDP1	TFDP2	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	SIRT6	ELF3	NOTCH3	NOTCH4	HIST1H2AJ	E2F3	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	RUNX1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	CCND1	H3F3B	HIST1H4K	HIST1H4L	NOTCH2	MAML2	MAML1	KAT2B	JUN	H3F3A	RBPJ	KAT2A	H2BFS	HIST1H4A	HIST1H4B	PRKCI	HIST1H4H	HIST1H4I	CREBBP	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	E2F1	HIST1H4F	HIST2H2AA3	HIST2H2AA4	TP53	
POLO-LIKE KINASE MEDIATED EVENTS%REACTOME%R-HSA-156711.2	Polo-like kinase mediated events	WEE1	FOXM1	PKMYT1	CDC25A	PLK1	LIN54	CDC25C	LIN37	LIN9	MYBL2	LIN52	CCNB2	CCNB1	CENPF	EP300	RBBP4	
REGULATION OF IFNG SIGNALING%REACTOME%R-HSA-877312.2	Regulation of IFNG signaling	IFNGR1	IFNGR2	PTPN6	SUMO1	PIAS1	PTPN11	JAK2	JAK1	PTPN1	SOCS1	SOCS3	IFNG	
DEFECTIVE SLC7A9 CAUSES CYSTINURIA (CSNU)%REACTOME DATABASE ID RELEASE 74%5660883	Defective SLC7A9 causes cystinuria (CSNU)	SLC7A9	SLC3A1	
DRUG RESISTANCE OF KIT MUTANTS%REACTOME%R-HSA-9669937.1	Drug resistance of KIT mutants	KIT	
ATP SENSITIVE POTASSIUM CHANNELS%REACTOME DATABASE ID RELEASE 74%1296025	ATP sensitive Potassium channels	KCNJ11	KCNJ8	ABCC8	ABCC9	
ACTIVATION OF THE MRNA UPON BINDING OF THE CAP-BINDING COMPLEX AND EIFS, AND SUBSEQUENT BINDING TO 43S%REACTOME%R-HSA-72662.3	Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	RPS26	RPS25	RPS28	RPS27	RPS29	RPS20	RPS21	RPS24	RPS23	RPS4X	RPS3A	PABPC1	RPS27L	RPS15A	EIF2S2	RPS3	EIF2S1	EIF4H	RPS27A	EIF2S3	RPS2	EIF4E	EIF4B	EIF3M	EIF3K	EIF3L	EIF3I	EIF3J	EIF4G1	EIF3G	EIF3H	EIF3E	EIF3F	FAU	EIF3C	EIF3D	EIF3A	EIF3B	EIF4A2	EIF4A1	RPS15	RPS14	RPS17	RPS16	RPS19	RPS18	RPS11	RPS10	RPS13	RPS12	RPS9	RPS7	EIF1AX	RPS8	RPS5	RPS6	RPSA	RPS4Y2	RPS4Y1	EIF4EBP1	
APC TRUNCATION MUTANTS ARE NOT K63 POLYUBIQUITINATED%REACTOME DATABASE ID RELEASE 74%5467333	APC truncation mutants are not K63 polyubiquitinated	APC	
DEFECTIVE GNE CAUSES SIALURIA, NONAKA MYOPATHY AND INCLUSION BODY MYOPATHY 2%REACTOME%R-HSA-4085011.1	Defective GNE causes sialuria, Nonaka myopathy and inclusion body myopathy 2	GNE	
DISORDERS OF DEVELOPMENTAL BIOLOGY%REACTOME DATABASE ID RELEASE 74%9675151	Disorders of Developmental Biology	CAMK4	TBL1X	HDAC1	TBL1XR1	SIN3A	HDAC3	PRKACA	NCOR2	NCOR1	GPS2	
REACTIONS SPECIFIC TO THE COMPLEX N-GLYCAN SYNTHESIS PATHWAY%REACTOME DATABASE ID RELEASE 74%975578	Reactions specific to the complex N-glycan synthesis pathway	CHST8	LHB	FUCA1	CHST10	FUT3	FUT8	CGA	MAN2A2	MAN2A1	MGAT2	
KETONE BODY METABOLISM%REACTOME%R-HSA-74182.3	Ketone body metabolism	HMGCL	ACSS3	BDH2	BDH1	OXCT1	OXCT2	HMGCS2	HMGCLL1	AACS	ACAT1	
BH3-ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI-APOPTOTIC BCL-2 MEMBERS%REACTOME%R-HSA-111453.5	BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	BCL2	BID	BCL2L11	PMAIP1	BBC3	BMF	BCL2L1	BAD	STAT3	
DEFECTIVE NTHL1 SUBSTRATE PROCESSING%REACTOME%R-HSA-9630221.1	Defective NTHL1 substrate processing	NTHL1	
NEGATIVE REGULATION OF NOTCH4 SIGNALING%REACTOME DATABASE ID RELEASE 74%9604323	Negative regulation of NOTCH4 signaling	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME1	PSME2	PSMD10	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	CUL1	PSMB6	PSMB7	PSMB4	UBB	YWHAZ	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	NOTCH4	AKT1	RBX1	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	TACC3	
GSD 0%REACTOME%R-HSA-3858516.2	GSD 0	GYS2	GYG2	
PROLINE CATABOLISM%REACTOME%R-HSA-70688.2	Proline catabolism	ALDH4A1	PRODH	PRODH2	
PLC BETA MEDIATED EVENTS%REACTOME%R-HSA-112043.1	PLC beta mediated events	ADCY2	ADCY1	ADCY8	ADCY7	CREB1	ADCY6	CAMK2G	PLA2G4A	ADCY5	GNAO1	GNAT1	PRKCG	PLCB4	PDE1C	PDE1B	PDE1A	ADRBK1	PRKCD	CAMKK1	CAMKK2	PRKAR2B	GNAT3	KPNA2	NBEA	CAMK4	MAPK1	AHCYL1	PRKX	GNAI3	GNAI1	GNAI2	PRKCA	GNAZ	PRKACG	PRKACB	GNAT2	ADCY9	PRKAR1B	PRKAR1A	PLCB3	PLCB1	PLCB2	PRKACA	CAMK2A	PRKAR2A	ITPR1	ITPR2	ITPR3	CAMK2B	ADCY4	CAMK2D	ADCY3	
SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE (SASP)%REACTOME DATABASE ID RELEASE 74%2559582	Senescence-Associated Secretory Phenotype (SASP)	HIST2H2AC	FOS	H2AFJ	UBE2D1	CDC23	CDC26	CDC27	ANAPC7	UBA52	H2AFZ	UBE2E1	H2AFX	H2AFV	CCNA2	CCNA1	HIST2H2BE	HIST4H4	ANAPC4	ANAPC5	ANAPC1	UBB	HIST1H2BN	HIST1H2BM	ANAPC2	ANAPC15	IGFBP7	HIST1H2BO	ANAPC16	UBC	VENTX	HIST1H2BJ	ANAPC10	HIST1H2BI	CDKN2D	ANAPC11	HIST1H2BL	CDKN2B	MAPK7	CDKN2C	RPS27A	HIST1H2BK	FZR1	HIST2H4A	HIST2H4B	MAPK1	UBE2C	UBE2S	CDC16	CDK2	CEBPB	EHMT1	CXCL8	IL6	CDK6	CDKN2A	STAT3	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	CDKN1A	CDKN1B	RELA	NFKB1	IL1A	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	EHMT2	H2AFB1	HIST1H3J	HIST1H3A	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	CDK4	HIST1H4L	JUN	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
INSULIN RECEPTOR SIGNALLING CASCADE%REACTOME%R-HSA-74751.3	Insulin receptor signalling cascade	MAPK3	IRS1	PTPN11	INS	FGF20	FGF23	GAB2	SHC1	FGF22	GAB1	FGF16	NRAS	PDPK1	SOS1	HRAS	FGF19	PIK3R2	FGF18	PIK3R1	FGFR4	PIK3CA	AKT2	TLR9	FGF10	FLT3	PDE3B	THEM4	INSR	TRIB3	MAPK1	KLB	FLT3LG	FRS2	IRS2	FGF1	PIK3CB	FGF2	FGF3	PIK3R4	FGF4	FGF6	FGF7	FGF9	GRB10	PIK3C3	
THE CANONICAL RETINOID CYCLE IN RODS (TWILIGHT VISION)%REACTOME DATABASE ID RELEASE 74%2453902	The canonical retinoid cycle in rods (twilight vision)	HSD17B1	RBP1	NAPEPLD	RDH16	RDH5	LRAT	STRA6	RHO	SDR9C7	MYO7A	HSD17B6	ABCA4	RPE65	RBP4	TTR	RDH12	RBP3	DHRS9	RDH11	RLBP1	CYP4V2	RDH10	
DEFECTIVE TBXAS1 CAUSES GHOSAL HEMATODIAPHYSEAL DYSPLASIA (GHDD)%REACTOME DATABASE ID RELEASE 74%5579032	Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)	TBXAS1	
RNA POLYMERASE I PROMOTER CLEARANCE%REACTOME%R-HSA-73854.3	RNA Polymerase I Promoter Clearance	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HDAC2	HDAC1	CBX3	MBD2	POLR2E	POLR2F	POLR2H	POLR2K	POLR2L	MAPK3	TBP	POLR1C	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	RRN3	CCNH	EHMT2	H2AFB1	CHD4	HIST1H3J	CHD3	TTF1	TAF1D	ZNRD1	HIST1H3A	MTA1	RBBP4	TAF1B	HIST1H3F	TAF1C	HIST1H3G	TWISTNB	TAF1A	HIST1H3H	UBTF	HIST1H3I	RBBP7	HIST1H3B	MTA2	HIST1H3C	MTA3	HIST1H3D	MBD3	CD3EAP	HIST1H3E	GTF2H1	GTF2H2	H3F3B	GTF2H3	HIST1H4K	GTF2H4	HIST1H4L	GATAD2B	GTF2H5	GATAD2A	KAT2B	H3F3A	CDK7	KAT2A	H2BFS	ERCC3	HIST1H4A	POLR1A	HIST1H4B	POLR1B	HIST1H4H	ERCC2	HIST1H4I	POLR1E	HIST1H4J	ERCC6	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
CATION-COUPLED CHLORIDE COTRANSPORTERS%REACTOME%R-HSA-426117.1	Cation-coupled Chloride cotransporters	SLC12A2	SLC12A3	SLC12A4	SLC12A5	SLC12A1	SLC12A6	SLC12A7	
SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE%REACTOME%R-HSA-1660516.7	Synthesis of PIPs at the early endosome membrane	PIK3C2A	PI4K2B	MTM1	MTMR10	MTMR12	INPP4A	INPP4B	INPP5F	PI4K2A	MTMR4	PIK3R4	PIK3C3	FIG4	VAC14	MTMR2	PIKFYVE	
EFFECTS OF PIP2 HYDROLYSIS%REACTOME%R-HSA-114508.2	Effects of PIP2 hydrolysis	ABHD12	PRKCH	PRKCE	DGKZ	DGKQ	DAGLB	DGKK	DGKI	DGKH	MGLL	PRKCQ	RASGRP2	RASGRP1	PRKCD	TRPC7	TRPC6	TRPC3	ITPR1	ITPR2	ITPR3	DGKG	DGKE	DGKD	DAGLA	DGKB	DGKA	ABHD6	
CONSTITUTIVE SIGNALING BY LIGAND-RESPONSIVE EGFR CANCER VARIANTS%REACTOME DATABASE ID RELEASE 74%1236382	Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	RPS27A	UBA52	SHC1	EGF	GAB1	CBL	EGFR	NRAS	HSP90AA1	CDC37	PLCG1	SOS1	HRAS	UBB	PIK3R1	PIK3CA	UBC	
BETA-OXIDATION OF VERY LONG CHAIN FATTY ACIDS%REACTOME%R-HSA-390247.3	Beta-oxidation of very long chain fatty acids	ACOT8	EHHADH	HSD17B4	DECR2	ACOT6	ACAA1	ABCD1	ACOT4	
IKBA VARIANT LEADS TO EDA-ID%REACTOME%R-HSA-5603029.2	IkBA variant leads to EDA-ID	NFKB1	NFKBIA	IKBKB	NFKB2	RELA	IKBKG	CHUK	
TOXICITY OF BOTULINUM TOXIN TYPE A (BONT A)%REACTOME%R-HSA-5250968.1	Toxicity of botulinum toxin type A (BoNT A)	SNAP25	SV2C	SV2B	SV2A	
POTENTIAL THERAPEUTICS FOR SARS%REACTOME%R-HSA-9679191.2	Potential therapeutics for SARS	JAK3	JAK1	ZBP1	TBK1	PHF21A	TLR7	AP2A1	TLR9	AP2A2	AP2M1	HMG20B	HDAC2	JAK2	HDAC1	FURIN	AP2S1	FKBP4	ARID4A	ARID4B	COMT	NR3C1	ROCK1	ITGA4	CYSLTR1	IL1R1	ACE2	ROCK2	SIGMAR1	RIPK1	ATP1B3	ATP1B2	TYK2	ATP1B1	AP2B1	SAP30	BRMS1	IFNGR1	IFNAR1	IFNGR2	ATP1A4	ATP1A3	ITGB1	ATP1A2	PTGES3	IL6R	ATP1A1	SAP30L	S1PR1	SAP18	SUDS3	CHD4	BRD4	CHD3	CRBN	STAT2	FKBP1A	REST	FXYD4	MTA1	FXYD3	RBBP4	IMPDH1	IMPDH2	FXYD2	FXYD1	FXYD7	FXYD6	RBBP7	PDCD1	MTA2	MTA3	HSP90AB1	MBD3	GATAD2B	GATAD2A	KDM1A	HSP90AA1	TUBB	
NRCAM INTERACTIONS%REACTOME%R-HSA-447038.1	NrCAM interactions	NRP2	NRCAM	CNTN2	DLG1	ANK1	DLG3	DLG4	
INOSITOL TRANSPORTERS%REACTOME DATABASE ID RELEASE 74%429593	Inositol transporters	SLC2A13	SLC5A11	SLC5A3	
DRUG RESISTANCE IN ERBB2 TMD JMD MUTANTS%REACTOME DATABASE ID RELEASE 74%9665737	Drug resistance in ERBB2 TMD JMD mutants	ERBB2	HSP90AA1	CDC37	ERBB2IP	
TGFBR2 KINASE DOMAIN MUTANTS IN CANCER%REACTOME DATABASE ID RELEASE 74%3645790	TGFBR2 Kinase Domain Mutants in Cancer	TGFB1	TGFBR1	TGFBR2	
DEFECTIVE NEU1 CAUSES SIALIDOSIS%REACTOME%R-HSA-4341670.1	Defective NEU1 causes sialidosis	NEU1	GLB1	CTSA	
GENERIC TRANSCRIPTION PATHWAY%REACTOME DATABASE ID RELEASE 74%212436	Generic Transcription Pathway	ABCA6	TBL1X	SUZ12	CDK5R1	TBL1XR1	SMAD4	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	DEK	BLK	ELF1	ELF2	PAX5	YWHAB	YWHAZ	MAPK14	MAPK11	BGLAP	RBX1	TGFA	GLI3	GLI2	GRIN2B	ITCH	BIRC5	AURKB	KIT	CSF2	ITGA2B	GPI	APAF1	NEDD4L	IL2	SMURF2	SMURF1	IL3	SMAD7	STUB1	PML	CCND2	RFC5	RFC3	PCNA	RFC4	RFC2	PPP2R5C	MET	CAMK2B	CAMK2D	CDKN1A	CDKN1B	PHF20	CAMK2G	CHEK2	PTPN11	CHEK1	ZNF385A	PCBP4	MDM2	IL2RA	MDM4	BTG2	KRAS	TNKS1BP1	CNOT6L	PRMT1	CDC25C	RBL2	RBL1	PLAGL1	E2F4	E2F7	E2F8	PLK3	NPM1	GADD45A	ARID3A	CNOT10	CNOT4	CNOT7	RGCC	CNOT1	CNOT11	CNOT2	CNOT3	CNOT8	ATF2	UBE2D3	MEF2C	ZNF17	ZNF287	ZNF18	RBFOX1	ZNF285	ZNF19	IRAK1	ZNF282	ZNF10	ZNF12	MAP2K6	ZNF14	JUN	AR	CLDN5	ZNF28	ZNF274	ZNF273	ZNF20	ZNF23	ZNF25	USP2	ZNF26	ZNF268	PPARGC1B	ZNF267	ZNF266	ZNF264	ZNF263	NR2F1	ZNF34	NR0B2	NR2F6	FOS	ZNF30	ZNF257	BCL2L11	ZNF256	ZNF496	ZNF254	ZNF253	ZNF493	ZNF492	ZNF250	UCMA	ZNF490	ZNF43	TNFRSF10D	ZNF45	HEY1	ZNF41	HEY2	CTLA4	ZNF248	ZNF486	ZNF485	ZNF484	CASP10	ZNF483	ACTL6B	RING1	CASP2	ZNF480	ACTL6A	SIRT3	ZNF479	ZNF235	ZNF234	ZNF233	PPARD	ZNF473	PTPN4	ZNF230	SERPINB13	ZNF471	ZNF470	HTT	ZNF227	ZNF468	ZNF226	ZNF225	ZNF224	ZNF223	ZNF222	MEN1	ZNF461	ZNF460	USP9X	ZNF77	ZNF79	SKI	ZNF70	ZNF71	ZNF74	AGRP	ZNF699	TFAP2A	ZNF215	TFAP2B	ZNF214	WWOX	ZNF697	TFAP2C	ZNF213	TFAP2D	ZNF696	TFAP2E	ZNF212	CITED1	ZNF454	CITED2	ZNF211	CITED4	ZNF692	YEATS4	ZNF691	RORC	MT-CO1	RORA	RORB	CTGF	TACO1	ZNF208	ZNF205	COX6A1	ZNF689	ZNF688	ZNF446	ZNF445	COX6B1	ZNF202	COX7A2L	SCO1	ZNF443	SCO2	ZNF200	ZNF684	MT-CO2	ZNF442	ZNF441	MT-CO3	ZNF682	ZNF440	ZNF681	COX19	ZNF680	COX16	ZFP69B	FOXP3	MAF	ZNF439	COX18	ZNF679	ZNF678	COX11	ZNF436	COX14	ZNF677	ZNF676	ZNF675	ZNF433	PVALB	ZNF432	SURF1	ZNF431	KMT2E	ZNF430	ZNF671	ZNF670	DLX5	DLX6	CYCS	KMT2B	FOXO6	FOXO4	ATXN3	COX20	ZKSCAN7	COX7B	MOBP	COX4I1	ZNF429	TAF9	ZKSCAN8	TAF1L	ZNF669	AK6	ZKSCAN3	COX7C	ZNF668	ZNF426	COX8A	TAF7L	ZKSCAN5	TAF9B	ZNF667	TAF15	ZNF425	TAF12	ZKSCAN4	TAF13	ZNF665	TAF10	ZNF664	TAF11	SOCS4	TAF4B	ZKSCAN1	TAF7	ZNF662	TAF6	ZNF660	TAF5	BDNF	TAF4	FBXO32	TAF3	ZNF419	TAF2	SP1	TAF1	ZNF418	ZNF417	ZNF658	ZNF416	ZNF415	ZNF655	SP7	ITGAL	ZNF649	YAF2	ZNF641	NKX3-2	COX5B	TRIM63	COX5A	TNFRSF18	HAND2	PPM1D	ZNF627	ZNF626	ZNF625	ZNF624	ZNF621	NDUFA4	ZNF620	E2F6	ZNF860	MGA	COX6C	TBX5	LRPPRC	PINK1	ZNF619	SST	ZNF616	ZNF615	ZNF614	ZNF613	ZNF611	ZNF610	TRIM33	SMARCB1	UXT	LGALS3	ZNF729	TRIM28	ZNF727	ZNF726	EPC1	ZNF721	ZNF720	SMARCC1	SMARCC2	ZFP1	ZFP2	ZNF716	ZNF713	ZNF711	ZNF710	ZNF324B	L3MBTL2	FOXG1	ZNF709	ZNF708	ZNF707	ZNF706	ZNF704	ZNF703	ZNF701	ZNF700	HIVEP3	SMARCA2	ITGBL1	MSTN	BMI1	HNF4A	SREBF1	PBRM1	SATB2	RXRB	ZFP14	ZNF585B	RXRG	ZNF585A	CCNG2	ZFP28	PRDM7	NPPA	ARID2	G6PC	MSX2	ZNF99	ZNF92	GPRIN1	ZFHX3	AUTS2	VDR	CAV1	BMP2	DPY30	TGIF1	RBM14	TGIF2	CAT	CAMK2A	RETN	LEF1	TCF7	RNF2	RRM2	ZNF804B	ZNF175	SERPINE1	ZSCAN32	ZNF169	JUNB	RNF111	ZNF705G	ZNF705D	MYB	ZNF160	ZNF705A	ZSCAN25	ZNF157	ZNF398	ZNF155	TCF7L2	ZNF154	TP53	ZNF394	TCF7L1	NKX2-5	ZFPM1	NR2C2AP	PHC2	ZNF141	ZNF383	GATA4	PHC1	GATA3	FOXO1	ZNF140	GATA2	ZNF382	GATA1	SETD1B	SETD1A	NR1D2	TNRC6C	MOV10	CDC7	ABL1	AGO3	NR1D1	AGO4	NFE2	PHC3	ZNF37A	CBX5	AGO1	ZNF138	PRDX2	ZNF136	AGO2	PRDX1	ZNF135	SOD2	ZNF133	BTG1	RSPO3	CDK5	CTNNB1	ZNF124	TEAD2	TNRC6A	ZIK1	TNRC6B	TEAD3	TEAD4	BRD2	ZNF724P	ZNF599	ZNF114	ZNF597	ZNF596	ZNF112	ZNF350	ZNF589	ZNF347	ZNF587	FOXO3	ZIM2	ZNF586	ZIM3	ZNF101	ZNF343	ZNF100	SIN3A	ZNF584	ZNF583	ZNF582	PCGF6	PCGF5	WWP1	ZNF33B	ZNF33A	RYBP	ZNF337	BRIP1	ZNF577	HDAC2	EXO1	ZNF334	HDAC1	ZNF333	TOPBP1	ATRIP	ZNF573	BARD1	ZNF331	RMI2	ZNF571	RMI1	WRN	ZNF570	HUS1	ZFP30	ZNF569	ZNF568	ZNF567	RAD17	ZNF566	RAD1	ZNF324	ZNF565	RAD9B	DNA2	RHNO1	ZFP37	ZNF564	ATR	ZNF563	RAD9A	ZNF562	ZNF320	ZNF561	ZNF560	NFATC2	NRBP1	ZNF559	ZNF317	ZNF558	ZNF557	PGR	ZNF799	ZNF556	ERBB2	ZNF555	ZNF554	ATM	ZNF311	ZNF552	FKBP5	MYL9	ZNF551	ZNF793	ZNF550	PTPN1	ZNF792	CSF1R	ZNF791	ZNF790	KRBA1	KRBOX4	ZNF549	YWHAQ	ZNF548	ZNF547	SFN	ZNF546	BID	ZNF304	YWHAH	ZNF544	ZNF302	ZNF786	ZNF543	ZNF785	SKIL	ZNF300	ZNF540	ESRRA	STAT1	ZNF782	ESRRB	ESRRG	ZFP69	ZNF778	ZNF777	ZNF776	ZNF775	ZNF774	ZNF773	ZNF530	ZNF772	ZNF771	ZNF770	SIN3B	ZNF529	ZNF528	ZNF764	ZNF521	LBR	MAPK3	CR1	ZNF75D	ZFP90	ZNF75A	ZNF519	ZNF517	ZNF514	ZNF510	ZNF750	HDAC4	SMARCD1	HDAC5	SMARCD2	HDAC8	HDAC9	HDAC7	EGFR	ZNF749	ZNF506	ZNF747	ZNF746	ZNF500	ZNF740	SMARCE1	ZNF738	ZNF737	ZNF736	ZNF735	ZNF732	ZNF730	HDAC10	HDAC11	TXNIP	ZNF607	ZNF606	ZNF605	TXN	ZNF600	SOX9	RUNX3	VEGFA	CGA	ZNF839	HKR1	TWIST2	TWIST1	OCLN	PRMT6	ZNF2	ZNF3	NPY	TJP1	ZNF354A	ZNF354C	ZNF354B	LMO1	LMO2	ATP1B4	LIFR	KCTD6	CBX8	SMAD1	CBX6	CBX4	CBX2	SMAD6	ESR2	NR4A2	APOE	NR4A1	NR4A3	THRB	THRA	SLC2A3	NR2E1	OPRM1	NR1H2	ARID1A	ARID1B	ZNF197	ZNF195	NR2C2	THBS1	NR2C1	ZNF189	ZNF286A	ZNF184	ZNF180	OPRK1	CASP1	YWHAE	POMC	PPP2R1A	PRKACA	YWHAG	SKP1	DGCR8	UBA52	CUL1	AURKA	CCNB1	UBB	UBC	BRCA1	RPS27A	NBN	TOP3A	BLM	RBBP8	RPA1	RPA2	MRE11A	MLH1	CENPJ	CDK1	RAD50	RAD51	RPA3	MDC1	CCNK	CEBPB	TP53RK	EHMT1	NOC2L	GLS	TP53AIP1	PIP4K2A	IGFBP1	PIP4K2B	PIP4K2C	NFYA	TP63	NFYB	DAXX	NFYC	DDIT4	L3MBTL1	DDIT3	MEAF6	NUAK1	TP53BP2	BANP	PRELID1	CRADD	TPX2	CDK12	CDK13	TP73	SETD9	CHM	BBC3	ING5	ING2	AIFM2	PRMT5	BRD1	DDB2	IL6	RAD51D	PLK2	SGK1	PMS2	BRD7	TIGAR	HIPK1	POU4F1	POU4F2	HIPK2	TTC5	CCNG1	CCNT2	PRDM1	SESN3	SESN2	BNIP3L	USP7	G6PD	IGFBP3	MSH2	FANCD2	KAT6A	MAPKAPK5	NDRG1	SMYD2	PMAIP1	BCL2L14	ZNF420	FANCI	BRPF1	SLMO1	BRPF3	TNFRSF10C	FANCC	TP53I3	BCL6	JMY	PIN1	PPP1R13B	DYRK2	PTEN	TRIAP1	PIDD1	CASP6	PPP1R13L	GPX2	RABGGTB	RABGGTA	RRM2B	TMEM219	TMEM55B	RNF34	GLS2	NLRC4	TP53INP1	RFFL	TXNRD1	SIRT1	CSNK2A1	SRC	CSNK2A2	HDAC6	BAX	NELFB	CSNK2B	SMAD2	SMAD3	TGFB1	NOTCH2	MAML2	MAML1	RBPJ	DLL1	EP300	HES1	JAG1	CREB1	MAML3	MAMLD1	GRIA2	GRIN2A	CAMK4	GPAM	GTF2F1	GTF2F2	YES1	PARP1	RB1	PPP2R1B	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	PRKCB	HIST1H2AJ	HIST2H3A	INS	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	CCNH	EHMT2	H2AFB1	CHD4	CHD3	HIST1H3J	HIST1H3A	RBBP4	HIST1H3F	HIST1H3G	HIST1H3H	RBBP7	HIST1H3I	MTA2	HIST1H3B	HIST1H3C	MBD3	HIST1H3D	HIST1H3E	GTF2H1	GTF2H2	H3F3B	GTF2H3	GTF2H4	HIST1H4K	GATAD2B	HIST1H4L	GTF2H5	GATAD2A	KAT2B	H3F3A	CDK7	KAT2A	H2BFS	ERCC3	HIST1H4A	SPI1	HIST1H4B	ERCC2	HIST1H4H	HIST1H4I	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	SETD8	NOP2	HIST2H2AC	H2AFJ	UBE2D1	CDC23	CDC26	CDC27	SKP2	ANAPC7	H2AFZ	UBE2E1	H2AFX	CCNA2	H2AFV	PPARGC1A	CCNA1	HIST2H2BE	CCNE2	CCNE1	HIST4H4	ANAPC4	ANAPC5	EZH2	ANAPC1	HIST1H2BN	HIST1H2BM	MED16	ANAPC2	MED15	ANAPC15	HIST1H2BO	ANAPC16	HIST1H2BJ	MED17	ANAPC10	HIST1H2BI	MED12	ANAPC11	HIST1H2BL	MED14	FZR1	HIST1H2BK	MED13	PPP2CA	MED10	HIST2H4A	PPP2CB	HIST2H4B	MAPK1	UBE2C	MED27	MED26	UBE2S	CDC16	CDK2	MED23	MED25	MED24	MED20	PPARG	PPARA	YY1	KMT2D	IHH	KMT2A	KMT2C	MED30	MED31	CRH	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	AXIN1	E2F1	PSMA5	PSMA6	PSMA3	PSMA4	RQCD1	PSMA1	CCNC	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PRKCQ	PSMD13	NOTCH1	MAX	PSMB10	PSMA7	MYBL2	E2F5	RELA	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	GAMT	NFKB1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PCK1	PSMC1	PSMC2	WWTR1	SMARCA4	SNW1	KDM5B	HNF4G	HSPD1	SUMO1	PITX2	UBE2I	ATAD2	KCTD1	ESR1	KCTD15	NR5A1	YAP1	TNFRSF10B	RXRA	NOTCH3	NOTCH4	TNFRSF10A	PERP	FASLG	FAS	SOCS3	IFNG	CCND3	PRR5	PDPK1	MAPKAP1	ITGA5	MTOR	AKT2	GPS2	AKT3	MLST8	AKT1	RICTOR	STEAP3	GSK3B	CCND1	CDK4	TCF3	LDB1	CREBBP	EED	CTDP1	ELL	CCNT1	SUPT4H1	TCEB3	TCEB2	VENTX	TCEB1	CARM1	NELFA	GAD1	CDKN2B	NELFCD	GAD2	TCEB3C	TCEB3CL	TCEB3B	NELFE	MYC	SUPT16H	SSRP1	SUPT5H	CDK9	TCEA1	TCEB3CL2	MED1	MED8	MED4	MED6	MED7	COL1A1	PRKAA1	PRKAA2	CBX3	RARG	PRKAG1	PRKAG2	ASH2L	PRKAG3	RPTOR	STK11	SLC38A9	PRKAB2	TEAD1	TSC2	TCF12	TSC1	PRKAB1	PPM1A	NCOR2	NCOR1	RRAGA	TAL1	RRAGC	RARA	RRAGB	RARB	RHEB	RRAGD	LAMTOR2	CDK6	CDKN2A	LAMTOR1	LAMTOR4	LAMTOR3	LAMTOR5	PCGF2	GCK	CBFB	PLXNA4	CTSV	CDK8	CNOT6	CTSL	CTSK	WDR5	TBP	TRPC3	MMP13	TFDP1	TFDP2	SMARCD3	HDAC3	SPP1	RBBP5	NR3C1	ITGA4	KLF4	KAT5	SOX2	RUNX1	GP1BA	PF4	
SIGNALING BY NTRK1 (TRKA)%REACTOME DATABASE ID RELEASE 74%187037	Signaling by NTRK1 (TRKA)	RALA	RALB	ASCL1	KIDINS220	FOS	CREB1	RIT1	RIT2	DNM1	FOSB	DUSP4	DNM2	CDK5R2	DNM3	DUSP6	CDK5	DUSP7	MAPK13	MAPK7	PPP2CA	SRF	PPP2CB	NGF	MAPK1	IRS2	PIK3CB	CDK5R1	CRKL	RAPGEF1	MAP2K1	MAP2K2	SHC2	SHC3	MEF2D	NAB1	NAB2	RAP1A	RHOA	TCF12	CRK	NTRK2	SGK1	ADCYAP1	ADCYAP1R1	PPP2R5D	STAT3	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	MAPK12	SHC1	YWHAB	NRAS	PLCG1	SOS1	HRAS	MAPKAPK2	AP2A1	AP2A2	AP2M1	EGR2	CLTC	CLTA	MAPK14	MAPK11	PPP2R1B	AP2S1	IRS1	AP2B1	SH3GL2	NTRK1	PIK3R2	ADORA2A	ATF1	PIK3R1	CHD4	ATF2	PIK3CA	REST	ELK1	MEF2A	MEF2C	VRK3	PPP2R1A	MAPKAPK3	FRS2	SH3GL3	ARC	TRIB1	TPH1	RRAD	MAP2K5	F3	JUNB	EGR1	RALGDS	JUND	EGR3	EGR4	BRAF	FOSL1	ID2	EP300	ID1	ID4	ID3	DNAL4	RPS6KA5	LYL1	DUSP3	VGF	
PROCESSING OF INTRONLESS PRE-MRNAS%REACTOME%R-HSA-77595.2	Processing of Intronless Pre-mRNAs	NCBP2	FIP1L1	CLP1	PCF11	PAPOLA	CSTF1	SYMPK	CPSF4	PABPN1	CPSF7	CPSF1	CPSF3	CSTF3	CSTF2	CPSF2	CSTF2T	WDR33	NCBP1	NUDT21	
FGFR2 LIGAND BINDING AND ACTIVATION%REACTOME DATABASE ID RELEASE 74%190241	FGFR2 ligand binding and activation	FGFBP1	FGFBP2	FGF20	FGFBP3	FGF1	FGF23	FGF2	FGF22	FGF3	FGF4	FGF16	FGF6	FGF7	FGF9	FGF18	FGF10	
PTK6 DOWN-REGULATION%REACTOME%R-HSA-8849472.1	PTK6 Down-Regulation	PTPN1	SRMS	PTK6	
DEFECTIVE CYP7B1 CAUSES SPASTIC PARAPLEGIA 5A, AUTOSOMAL RECESSIVE (SPG5A) AND CONGENITAL BILE ACID SYNTHESIS DEFECT 3 (CBAS3)%REACTOME%R-HSA-5579013.1	Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3)	CYP7B1	
E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS%REACTOME DATABASE ID RELEASE 74%8866654	E3 ubiquitin ligases ubiquitinate target proteins	UBE2D2	UBE2D1	VCP	UBA52	UBE2E1	BCL10	UBE2N	HIST1H2BN	UBB	HIST1H2BM	HIST1H2BO	HIST1H2BJ	UBC	HIST1H2BI	HIST1H2BL	RPS27A	HIST1H2BK	HLA-A	DERL1	HIST1H2BF	HIST1H2BE	HIST1H2BH	CDC73	HIST1H2BG	UBE2L3	RNF152	HIST1H2BB	SHPRH	PEX2	HIST1H2BA	RNF40	RNF144A	HIST1H2BD	WAC	HIST1H2BC	UBE2V2	VIMP	PRKDC	CTR9	WDR61	RTF1	UBE2D3	UBE2J2	RRAGA	HLTF	TMEM129	LEO1	RNF20	UBE2B	PEX10	UBE2A	PEX12	PEX13	PEX14	RNF181	PAF1	PCNA	RAD18	
INHIBITION OF SIGNALING BY OVEREXPRESSED EGFR%REACTOME%R-HSA-5638303.1	Inhibition of Signaling by Overexpressed EGFR	TGFA	AREG	EGFR	EPGN	EREG	BTC	EGF	HBEGF	
AUF1 (HNRNP D0) BINDS AND DESTABILIZES MRNA%REACTOME%R-HSA-450408.3	AUF1 (hnRNP D0) binds and destabilizes mRNA	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	HSPB1	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	PABPC1	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	HSPA8	EIF4G1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
SIGNALING BY NOTCH3%REACTOME DATABASE ID RELEASE 74%9012852	Signaling by NOTCH3	MIB2	NOTCH3	MIB1	NCSTN	NEURL1	MAML3	MAMLD1	UBA52	NOTCH1	EGF	EGFR	HEY1	HEY2	PBX1	UBB	UBC	RPS27A	SNW1	STAT1	MAML2	PLXND1	WWC1	MAML1	YBX1	KAT2B	PSEN2	DLGAP5	WWP2	RBPJ	PTCRA	ADAM10	KAT2A	DLL1	HEYL	DLL4	FABP7	APH1A	NEURL1B	APH1B	CREBBP	EP300	HES1	HES5	JAG2	PSEN1	PSENEN	JAG1	TACC3	
METHYLATION%REACTOME DATABASE ID RELEASE 74%156581	Methylation	N6AMT1	MTRR	NNMT	AHCY	TPMT	COMT	GSTO1	MTR	CYP1A2	MAT2B	MAT1A	AS3MT	MAT2A	TRMT112	
LATE PHASE OF HIV LIFE CYCLE%REACTOME%R-HSA-162599.2	Late Phase of HIV Life Cycle	VPS37C	VPS37D	VPS37A	VPS37B	NUP62	CHMP2B	CHMP2A	CHMP4C	NDC1	CHMP4B	SEC13	NUP133	UBAP1	UBA52	CHMP3	CHMP4A	RANGAP1	CHMP6	CHMP7	VPS28	NUP50	CHMP5	NUP54	CTDP1	UBB	ELL	CCNT1	SUPT4H1	TCEB3	UBC	TCEB2	TCEB1	NELFA	NELFCD	TCEB3C	RPS27A	TCEB3CL	TCEB3B	NELFE	SUPT16H	SSRP1	SUPT5H	CDK9	NUP43	RAE1	TCEA1	TCEB3CL2	RANBP2	NUP35	NUPL2	NUP37	CCNK	PPIA	NEDD4L	POLR2A	POLR2B	POLR2C	NCBP1	POLR2D	NCBP2	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	CCNT2	GTF2A1	GTF2A2	GTF2B	TAF9	TAF1L	AK6	GTF2E1	GTF2E2	TAF7L	TAF9B	TAF15	TAF12	TAF13	TAF10	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	RCC1	NMT1	XPO1	NMT2	PDCD6IP	RNMT	RANBP1	RNGTT	TBP	GTF2F1	GTF2F2	RAN	NUP107	NUP188	FURIN	NUP214	NUP210	NUP93	NELFB	NUP205	CCNH	POM121	AAAS	NUP160	NUP85	TPR	NUP88	GTF2H1	NUP155	GTF2H2	GTF2H3	GTF2H4	GTF2H5	CDK7	NUP153	ERCC3	ERCC2	TSG101	MNAT1	VPS4B	VPS4A	MVB12B	MVB12A	VTA1	
AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL%REACTOME%R-HSA-198323.3	AKT phosphorylates targets in the cytosol	CDKN1A	AKT1S1	AKT1	CDKN1B	MDM2	GSK3B	MKRN1	GSK3A	TSC2	CASP9	AKT2	CHUK	AKT3	BAD	
COSTIMULATION BY THE CD28 FAMILY%REACTOME DATABASE ID RELEASE 74%388841	Costimulation by the CD28 family	PAK3	CSK	PAK2	PTPN11	CTLA4	LYN	PPP2CA	PPP2CB	CD3G	RAC1	YES1	VAV1	CD3E	CD3D	ICOSLG	PPP2R1B	HLA-DPA1	PDCD1LG2	CDC42	HLA-DQB2	HLA-DQB1	CD274	BTLA	TNFRSF14	HLA-DQA2	HLA-DQA1	TRAV19	HLA-DRB5	HLA-DRB4	CD4	HLA-DPB1	HLA-DRA	HLA-DRB3	HLA-DRB1	PRR5	PTPN6	CD86	PDPK1	MAPKAP1	CD80	PIK3R3	PIK3R2	PIK3R1	MTOR	PIK3CA	LCK	AKT2	GRAP2	AKT3	MLST8	CD28	THEM4	AKT1	TRIB3	MAP3K8	FYN	PDCD1	RICTOR	PPP2R1A	MAP3K14	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	PAK1	
ROS AND RNS PRODUCTION IN PHAGOCYTES%REACTOME DATABASE ID RELEASE 74%1222556	ROS and RNS production in phagocytes	ATP6V0C	ATP6V1B1	ATP6V1A	ATP6V0A2	ATP6V1H	CYBA	ATP6V0A4	ATP6V1G3	ATP6V0E2	ATP6V1D	ATP6V1C1	ATP6V1C2	ATP6V0A1	NCF1	ATP6V1F	NCF2	NCF4	LPO	MPO	RAC2	NOS1	NOS2	NOS3	SLC11A1	CYBB	TCIRG1	ATP6V1E1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	HVCN1	ATP6V1B2	ATP6V0D1	ATP6V0D2	
REMOVAL OF THE FLAP INTERMEDIATE FROM THE C-STRAND%REACTOME DATABASE ID RELEASE 74%174437	Removal of the Flap Intermediate from the C-strand	DNA2	TINF2	TERF1	TERF2	FEN1	PCNA	RPA1	POT1	RPA2	TERF2IP	ACD	POLD3	POLD4	RPA3	POLD1	POLD2	WRN	
LOSS OF FUNCTION OF SMAD2 3 IN CANCER%REACTOME DATABASE ID RELEASE 74%3304349	Loss of Function of SMAD2 3 in Cancer	SMAD2	SMAD3	TGFB1	TGFBR1	TGFBR2	SMAD4	
SIGNALING BY EGFRVIII IN CANCER%REACTOME%R-HSA-5637812.1	Signaling by EGFRvIII in Cancer	SHC1	EGF	GAB1	CBL	EGFR	NRAS	HSP90AA1	CDC37	PLCG1	SOS1	HRAS	PIK3R1	PIK3CA	
TOLL LIKE RECEPTOR 10 (TLR10) CASCADE%REACTOME%R-HSA-168142.1	Toll Like Receptor 10 (TLR10) Cascade	RPS6KA1	RIPK2	MAPK3	IRAK4	FOS	CREB1	DUSP4	TRAF6	PELI1	UBA52	TLR10	UBE2V1	TLR5	DUSP6	DUSP7	CUL1	RELA	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	AGER	BTRC	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
TRANSCRIPTION OF THE HIV GENOME%REACTOME DATABASE ID RELEASE 74%167172	Transcription of the HIV genome	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	CTDP1	RNMT	ELL	CCNT1	RNGTT	SUPT4H1	TCEB3	TCEB2	TCEB1	NELFA	NELFCD	TCEB3C	TCEB3CL	TCEB3B	TBP	NELFE	GTF2F1	SUPT16H	GTF2F2	SSRP1	SUPT5H	CDK9	TCEA1	TCEB3CL2	CCNK	NELFB	CCNH	POLR2A	POLR2B	POLR2C	NCBP1	POLR2D	NCBP2	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	CCNT2	GTF2H3	GTF2H4	GTF2H5	GTF2A1	CDK7	GTF2A2	GTF2B	ERCC3	TAF9	TAF1L	AK6	ERCC2	GTF2E1	GTF2E2	TAF7L	MNAT1	TAF9B	TAF15	TAF12	TAF13	TAF10	
RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PYRIMIDINE%REACTOME DATABASE ID RELEASE 74%110328	Recognition and association of DNA glycosylase with site containing an affected pyrimidine	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST3H3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	OGG1	TINF2	TERF1	TERF2	NEIL3	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	NEIL2	NEIL1	TDG	MBD4	SMUG1	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	NTHL1	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
SUPPRESSION OF PHAGOSOMAL MATURATION%REACTOME DATABASE ID RELEASE 74%9637687	Suppression of phagosomal maturation	RPS27A	KPNA1	KPNB1	HGS	ATP6V1H	VPS33B	UBA52	CORO1A	RAB7A	UBB	RAB5A	NOS2	UBC	
REACTIONS SPECIFIC TO THE HYBRID N-GLYCAN SYNTHESIS PATHWAY%REACTOME%R-HSA-975574.1	Reactions specific to the hybrid N-glycan synthesis pathway	MGAT3	
PROGRAMMED CELL DEATH%REACTOME%R-HSA-5357801.2	Programmed Cell Death	RIPK3	DYNLL1	GZMB	UNC5A	PAK2	UNC5B	MAGED1	LMNB1	BCL2L11	UBA52	PELI1	BIRC2	DAPK1	CTNNB1	DAPK2	DAPK3	BIRC3	OMA1	UBB	CLSPN	MLKL	BMX	H1F0	UBC	STK24	STK26	OGT	MAPK8	HMGB2	OPA1	RPS27A	HIST1H1D	FLOT1	HIST1H1E	FLOT2	DNM1L	HIST1H1A	MAPK1	HIST1H1B	HIST1H1C	APPL1	DFFB	DFFA	DBNL	ARHGAP10	GAS2	MAPT	PLEC	SATB1	BCAP31	AVEN	GSN	FNTA	APAF1	ACIN1	DIABLO	VIM	CARD8	TJP2	APIP	XIAP	UACA	CASP9	CASP7	BAK1	DYNLL2	ROCK1	TP63	SDCBP	PKP1	TP53BP2	TP73	STUB1	BBC3	DCC	BCL2L1	BAD	PPP3CC	YWHAQ	BCL2	SFN	BID	YWHAH	CDKN2A	CDH1	CYCS	DSP	STAT3	PSMD8	DSG1	PSMD9	PSMD6	DSG2	PSMD7	DSG3	PSMD4	PSMD5	PSMD2	PSMD3	PMAIP1	PSMD1	APC	E2F1	PSMA5	PSMA6	PSMA3	MAPK3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PPP1R13B	PSME2	PSMD10	PSMB11	PSMD12	CASP6	PSMD11	PRKCQ	PSMD14	ADD1	PSMD13	YWHAB	PSMB10	PSMA7	CDC37	NMT1	PSMA8	PDCD6IP	PSMB6	PSMB7	PRKCD	PSMB4	YWHAZ	PSMB5	CASP3	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	KPNA1	PSMC5	PSMC6	KPNB1	PSMC3	PSMC4	PSMC1	PSMC2	OCLN	TJP1	TFDP1	TFDP2	TICAM2	TRADD	LY96	TNFRSF10B	TRAF2	TNFRSF10A	SPTAN1	FASLG	TICAM1	CASP8	TNFSF10	FAS	RIPK1	BAX	CD14	FADD	TLR4	AKT2	AKT3	YWHAE	AKT1	C1QBP	YWHAG	PPP3R1	HSP90AA1	HMGB1	PTK2	BMF	TP53	
FORMATION OF HIV ELONGATION COMPLEX IN THE ABSENCE OF HIV TAT%REACTOME%R-HSA-167152.3	Formation of HIV elongation complex in the absence of HIV Tat	CCNK	NELFB	CTDP1	CCNH	ELL	CCNT1	SUPT4H1	POLR2A	TCEB3	POLR2B	TCEB2	POLR2C	TCEB1	NELFA	POLR2D	NELFCD	NCBP1	TCEB3C	NCBP2	POLR2E	TCEB3CL	POLR2F	TCEB3B	NELFE	GTF2F1	POLR2G	SUPT16H	GTF2F2	POLR2H	SSRP1	POLR2I	SUPT5H	POLR2J	CDK9	TCEA1	POLR2K	TCEB3CL2	POLR2L	GTF2H1	GTF2H2	CCNT2	GTF2H3	GTF2H4	GTF2H5	CDK7	ERCC3	ERCC2	MNAT1	
PROSTANOID LIGAND RECEPTORS%REACTOME%R-HSA-391908.1	Prostanoid ligand receptors	PTGER3	PTGER4	PTGER2	PTGFR	TBXA2R	PTGIR	PTGDR2	PTGDR	PTGER1	
INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS%REACTOME%R-HSA-141405.4	Inhibition of the proteolytic activity of APC C required for the onset of anaphase by mitotic spindle checkpoint components	UBE2C	UBE2D1	CDC23	UBE2S	CDC26	CDC16	CDC27	ANAPC7	UBE2E1	ANAPC4	BUB1B	ANAPC5	CDC20	BUB3	ANAPC1	MAD2L1	ANAPC2	ANAPC15	ANAPC16	ANAPC10	ANAPC11	
PPARA ACTIVATES GENE EXPRESSION%REACTOME DATABASE ID RELEASE 74%1989781	PPARA activates gene expression	ARNT	CYP1A1	AHRR	TGS1	NR1D1	ABCB4	PPARGC1A	MED19	MED16	MED15	MED18	MED17	CARM1	MED12	MED11	MED14	TBL1X	MED13	MED10	MED27	MED26	MED1	MED29	MED8	MED28	MED9	APOA1	MED23	MED4	MED22	MED25	MED24	MED21	MED6	MED20	PPARG	MED7	PPARA	CDK19	TBL1XR1	RORA	NFYA	NFYB	NFYC	MED30	MED31	NCOR2	NCOR1	THRAP3	FADS1	SULT2A1	CPT1A	ACSL1	CLOCK	PEX11A	NRF1	NPAS2	FDFT1	ALAS1	FAM120B	FHL2	GLIPR1	CPT2	ME1	ANKRD1	ESRRA	ACADM	HMGCS1	CYP4A11	MTF1	PLIN2	TNFRSF21	CYP7A1	ARNTL	UGT1A9	NR1H4	G0S2	GRHL1	AGT	FABP1	CCNC	SP1	CDK8	TXNRD1	APOA2	MED13L	APOA5	NCOA1	ANGPTL4	SLC27A1	NCOA2	NCOA6	NCOA3	SMARCD3	SREBF2	HDAC3	RXRA	ABCA1	NR1H2	NR1H3	RXRB	GPS2	TRIB3	HELZ2	AHR	HMGCS2	CHD9	CREBBP	EP300	TIAM2	PPARGC1B	CD36	ARNT2	RGL1	
GLUCAGON-TYPE LIGAND RECEPTORS%REACTOME DATABASE ID RELEASE 74%420092	Glucagon-type ligand receptors	SCTR	GNG12	GNG11	GNG13	GCG	GHRH	VIP	GLP1R	GNB2	VIPR1	GNB1	VIPR2	SCT	GNB4	GNB3	GNB5	CYSLTR2	GNGT1	GLP2R	GNGT2	GIP	ADCYAP1	ADCYAP1R1	GIPR	GNAS	GNG3	GNG10	GNG2	GHRHR	GNG5	GNG4	GNG7	GNG8	
SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER%REACTOME DATABASE ID RELEASE 74%2691230	Signaling by NOTCH1 HD Domain Mutants in Cancer	MIB2	RPS27A	MIB1	NEURL1	UBA52	NOTCH1	ADAM10	DLL1	DLL4	ADAM17	NEURL1B	UBB	UBC	JAG2	JAG1	
RNA POLYMERASE III TRANSCRIPTION TERMINATION%REACTOME DATABASE ID RELEASE 74%73980	RNA Polymerase III Transcription Termination	POLR2E	POLR2F	SSB	POLR3GL	POLR2H	POLR3A	POLR3B	NFIA	POLR2K	POLR3C	POLR2L	NFIB	POLR3D	NFIC	POLR3E	POLR1C	POLR3F	POLR3G	POLR3H	POLR3K	CRCP	NFIX	
ASSEMBLY OF THE HIV VIRION%REACTOME%R-HSA-175474.1	Assembly Of The HIV Virion	VPS37C	RPS27A	VPS37D	VPS37A	VPS37B	PPIA	UBAP1	UBA52	VPS28	NMT2	UBB	TSG101	FURIN	UBC	MVB12B	MVB12A	
BIOSYNTHESIS OF DPA-DERIVED SPMS%REACTOME DATABASE ID RELEASE 74%9018683	Biosynthesis of DPA-derived SPMs	PTGS2	ALOX15	ALOX12	ALOX5	
ANTIMICROBIAL ACTION AND ANTIMICROBIAL RESISTANCE IN MTB%REACTOME%R-HSA-9639775.2	Antimicrobial action and antimicrobial resistance in Mtb	
FGFR2B LIGAND BINDING AND ACTIVATION%REACTOME%R-HSA-190377.2	FGFR2b ligand binding and activation	FGF7	FGFBP1	FGFBP2	FGFBP3	FGF1	FGF10	FGF2	FGF22	FGF3	
DOWNSTREAM SIGNAL TRANSDUCTION%REACTOME%R-HSA-186763.2	Downstream signal transduction	STAT6	SRC	PTPN11	GRB7	NRAS	PLCG1	SOS1	HRAS	PIK3R2	PIK3R1	PIK3CA	CRK	BCAR1	STAT5A	STAT5B	NCK2	PIK3CB	STAT1	STAT3	PDGFB	CRKL	RAPGEF1	NCK1	PDGFRB	RASA1	PDGFRA	
CARNITINE METABOLISM%REACTOME%R-HSA-200425.5	Carnitine metabolism	CPT1A	RXRA	PPARD	PRKAB2	SLC22A5	MID1IP1	THRSP	SLC25A20	CPT2	CPT1B	PRKAA2	PRKAG2	
SIGNALING BY EGFR IN CANCER%REACTOME DATABASE ID RELEASE 74%1643713	Signaling by EGFR in Cancer	RPS27A	AREG	EPGN	UBA52	EREG	SHC1	BTC	EGF	GAB1	CBL	TGFA	EGFR	NRAS	HSP90AA1	CDC37	PLCG1	SOS1	HRAS	UBB	PIK3R1	PIK3CA	UBC	HBEGF	
ION CHANNEL TRANSPORT%REACTOME DATABASE ID RELEASE 74%983712	Ion channel transport	ATP6V0C	RAF1	ATP6V1B1	ATP8A2	ATP8A1	ATP12A	ATP6V1A	BEST2	BEST3	SLC9C1	SLC9C2	BEST1	ATP6V0A2	BEST4	ATP6V1H	SLN	ATP11C	UBA52	ATP6V0A4	ATP11B	ATP6V1G3	ATP11A	ATP6V0E2	TRPC4AP	ATP6V1D	SLC9B1	ATP6V1C1	SLC9B2	SCNN1G	ATP6V1C2	SCNN1D	ATP6V0A1	SCNN1B	ATP6V1F	SCNN1A	TTYH3	MCOLN1	TTYH2	CLCNKB	UBB	WNK4	CLCNKA	NALCN	TRPM1	UBC	TRPM2	ASIC4	ASIC5	CLCA2	RPS27A	CLCA1	TRPM7	TRPM8	ASIC2	TRPM5	TRPM6	ASIC3	CLCA4	TRPM3	ASIC1	TRPM4	ATP8B4	ATP8B3	ATP8B2	ATP8B1	TRPV2	WWP1	TRPV3	TRPV1	ATP4B	ATP4A	TRPV6	WNK1	WNK2	TRPV4	WNK3	TRPV5	CUTC	RYR1	RYR2	ATP2A3	ATP2A2	ATP2A1	RYR3	UNC80	ATP7B	CLIC2	ATP7A	TSC22D3	ANO8	ANO9	ANO6	ANO7	ANO4	ANO5	NEDD4L	ANO2	TRDN	ANO3	ANO1	ASPH	SGK3	SGK2	STOML3	ATP10D	ATP10B	ATP10A	ATP2C2	SRI	CLCN6	CLCN3	ATP2C1	CLCN2	CLCN1	PLN	BSND	ANO10	STOM	SGK1	ATP9B	SLC17A3	ATP9A	MCOLN3	TRPA1	ATP13A1	ATP2B4	ATP2B3	ATP2B2	ATP2B1	MCOLN2	TPCN2	TPCN1	CLCN7	CLCN5	CLCN4	OSTM1	FKBP1B	ATP13A4	ATP13A5	ATP13A2	UNC79	CAMK2B	CAMK2D	CAMK2G	TRPC7	TRPC5	TRPC6	TRPC3	TRPC4	TRPC1	PDZD11	ATP1B3	ATP1B2	ATP1B1	ATP1A4	ATP1A3	ATP1A2	ATP1A1	FXYD4	FXYD3	FXYD2	FXYD1	FXYD7	FXYD6	CAMK2A	TCIRG1	ATP6V1E1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	ATP6AP1	ATP6V1B2	ATP6V0D1	ATP6V0D2	
ERBB2 REGULATES CELL MOTILITY%REACTOME%R-HSA-6785631.3	ERBB2 Regulates Cell Motility	RHOA	EREG	BTC	EGF	NRG1	ERBB2	EGFR	NRG2	NRG3	NRG4	MEMO1	DIAPH1	HBEGF	
APOPTOSIS%REACTOME DATABASE ID RELEASE 74%109581	Apoptosis	DYNLL1	GZMB	UNC5A	PAK2	UNC5B	MAGED1	LMNB1	BCL2L11	UBA52	BIRC2	DAPK1	CTNNB1	DAPK2	DAPK3	OMA1	UBB	CLSPN	BMX	H1F0	UBC	STK24	STK26	MAPK8	HMGB2	OPA1	RPS27A	HIST1H1D	HIST1H1E	DNM1L	HIST1H1A	MAPK1	HIST1H1B	HIST1H1C	APPL1	DFFB	DFFA	DBNL	ARHGAP10	GAS2	MAPT	PLEC	SATB1	BCAP31	AVEN	GSN	FNTA	APAF1	ACIN1	DIABLO	VIM	CARD8	TJP2	APIP	XIAP	UACA	CASP9	CASP7	BAK1	DYNLL2	ROCK1	TP63	PKP1	TP53BP2	TP73	BBC3	DCC	BCL2L1	BAD	PPP3CC	YWHAQ	BCL2	SFN	BID	YWHAH	CDKN2A	CDH1	CYCS	DSP	STAT3	PSMD8	DSG1	PSMD9	PSMD6	DSG2	PSMD7	DSG3	PSMD4	PSMD5	PSMD2	PSMD3	PMAIP1	PSMD1	APC	E2F1	PSMA5	PSMA6	PSMA3	MAPK3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PPP1R13B	PSME2	PSMD10	PSMB11	PSMD12	CASP6	PSMD11	PRKCQ	PSMD14	ADD1	PSMD13	YWHAB	PSMB10	PSMA7	NMT1	PSMA8	PSMB6	PSMB7	PRKCD	PSMB4	YWHAZ	PSMB5	CASP3	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	KPNA1	PSMC5	PSMC6	KPNB1	PSMC3	PSMC4	PSMC1	PSMC2	OCLN	TJP1	TFDP1	TFDP2	TICAM2	TRADD	LY96	TNFRSF10B	TRAF2	TNFRSF10A	SPTAN1	FASLG	TICAM1	CASP8	TNFSF10	FAS	RIPK1	BAX	CD14	FADD	TLR4	AKT2	AKT3	YWHAE	AKT1	C1QBP	YWHAG	PPP3R1	HMGB1	PTK2	BMF	TP53	
ERYTHROPOIETIN ACTIVATES RAS%REACTOME DATABASE ID RELEASE 74%9027284	Erythropoietin activates RAS	VAV1	EPOR	NRAS	CRKL	RAPGEF1	LYN	JAK2	SOS1	HRAS	EPO	IRS2	SHC1	
RRNA PROCESSING IN THE MITOCHONDRION%REACTOME%R-HSA-8868766.2	rRNA processing in the mitochondrion	TRMT10C	NSUN4	RNMTL1	ELAC2	MTERF4	TFB1M	FTSJ2	KIAA0391	HSD17B10	MRM1	
DNA DAMAGE REVERSAL%REACTOME DATABASE ID RELEASE 74%73942	DNA Damage Reversal	ALKBH3	FTO	ALKBH2	ALKBH5	MGMT	ASCC1	ASCC2	ASCC3	
SIGNALING BY PHOSPHORYLATED JUXTAMEMBRANE, EXTRACELLULAR AND KINASE DOMAIN KIT MUTANTS%REACTOME DATABASE ID RELEASE 74%9670439	Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	FYN	STAT5A	STAT5B	YES1	STAT1	STAT3	NRAS	LYN	JAK2	SOS1	PIK3R3	HRAS	PIK3R2	PIK3R1	PIK3CA	LCK	KIT	
DEFECTIVE CHST6 CAUSES MCDC1%REACTOME DATABASE ID RELEASE 74%3656225	Defective CHST6 causes MCDC1	CHST6	LUM	OGN	OMD	PRELP	KERA	FMOD	
HSF1 ACTIVATION%REACTOME%R-HSA-3371511.1	HSF1 activation	RPA3	PTGES3	HSP90AA1	HDAC6	EEF1A1	HSP90AB1	RPA1	RPA2	VCP	HSBP1	YWHAE	HSF1	
PROCESSING OF CAPPED INTRON-CONTAINING PRE-MRNA%REACTOME%R-HSA-72203.3	Processing of Capped Intron-Containing Pre-mRNA	NUP62	NDC1	SEC13	NUP133	NUP50	SKIV2L2	NUP54	CPSF7	CPSF1	CPSF3	CSTF3	CSTF2	CPSF2	CSTF2T	WDR33	NUDT21	FIP1L1	CLP1	PCF11	PAPOLA	CSTF1	SYMPK	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	YBX1	ELAVL1	LSM5	LSM4	LSM3	LSM2	LSM7	LSM6	EIF4E	HSPA8	SNW1	HNRNPU	HNRNPR	CCAR1	SNRPD2	SNRPD1	SNRPD3	SRRM2	AQR	METTL3	CRNKL1	CD2BP2	SF1	SLBP	DHX9	RNPC3	PCBP1	PCBP2	ZRSR2	PRPF38A	HNRNPL	HNRNPM	HNRNPK	HNRNPF	HNRNPD	HNRNPC	SUGP1	PRPF19	PQBP1	DHX15	DHX16	PRPF40A	GCFC2	HNRNPH1	HNRNPH2	SF3B4	SF3B5	SF3B2	SF3B3	SF3B6	SRRT	SRSF10	SF3B1	SF3A3	SF3A1	SF3A2	XAB2	PHF5A	HNRNPA2B1	PRPF31	PDCD7	CWC25	CWC27	EFTUD2	CWC22	SNRNP35	TXNL4A	SNRPN	ZCRB1	WBP11	PRPF4	PRPF6	HNRNPUL1	NXT1	EIF4A3	PRPF3	CASC3	SNRPG	GLE1	SNRNP27	MAGOH	PPIE	PPIH	NCBP1	SNRPE	NCBP2	THOC1	SNRPF	THOC3	SNRNP25	THOC2	SNRPC	THOC5	SNRNP200	THOC7	SNRPA	CDC40	SNRPB	SRRM1	DDX5	THOC6	PRPF8	DDX39A	ZMAT5	DDX39B	FUS	SARNP	CWC15	ZC3H11A	CHERP	SRSF2	LSM8	SRSF3	ISY1	SRSF4	DDX46	SRSF5	DDX42	SRSF6	PPWD1	SRSF7	USP39	SLU7	ELAVL2	SRSF9	PTBP1	FYTTD1	SART1	METTL14	LUZP4	RBM8A	SNRNP70	CTNNBL1	POLDIP3	BCAS2	SRSF1	RBM5	U2AF1	RBM17	U2AF1L4	BUD31	NXF1	TFIP11	NXF2	PLRG1	U2AF2	DHX38	SYF2	SRSF11	SNRPA1	CHTOP	DNAJC8	UPF3B	RBM22	MAGOHB	PRCC	NXF2B	WBP4	RNPS1	DDX23	PUF60	TRA2B	SNRPB2	HNRNPA1	SMNDC1	HNRNPA0	PPIL1	HNRNPA3	WTAP	GPKOW	CDC5L	U2SURP	SNRNP40	SNRNP48	PPIL3	PPIL4	RBMX	PPIL6	GTF2F1	GTF2F2	CPSF4	PABPN1	NUP107	NUP188	NUP214	NUP210	NUP93	NUP205	POM121	AAAS	NUP160	NUP85	TPR	NHP2L1	NUP88	NUP155	NUP153	
DEFECTIVE CYP2U1 CAUSES SPASTIC PARAPLEGIA 56, AUTOSOMAL RECESSIVE (SPG56)%REACTOME%R-HSA-5579011.1	Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56)	CYP2U1	
DEFECTIVE ABCD4 CAUSES MAHCJ%REACTOME DATABASE ID RELEASE 74%5683329	Defective ABCD4 causes MAHCJ	ABCD4	
MATURATION OF PROTEIN E%REACTOME DATABASE ID RELEASE 74%9694493	Maturation of protein E	RPS27A	UBB	UBC	UBA52	
PECAM1 INTERACTIONS%REACTOME%R-HSA-210990.1	PECAM1 interactions	PTPN6	LYN	FYN	PLCG1	PTPN11	LCK	ITGAV	YES1	INPP5D	ITGB3	
APC C:CDC20 MEDIATED DEGRADATION OF SECURIN%REACTOME%R-HSA-174154.2	APC C:Cdc20 mediated degradation of Securin	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	ANAPC4	PSMA8	ANAPC5	PSMB6	PSMB7	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	PSMC2	UBE2S	CDC16	PTTG1	CDC20	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
SHC-MEDIATED CASCADE:FGFR4%REACTOME%R-HSA-5654719.2	SHC-mediated cascade:FGFR4	KLB	FGF20	FGF1	FGF23	FGF2	FGF4	FGF16	FGF6	NRAS	FGF9	SOS1	FGF19	HRAS	FGF18	FGFR4	
TOLL LIKE RECEPTOR TLR1:TLR2 CASCADE%REACTOME%R-HSA-168179.1	Toll Like Receptor TLR1:TLR2 Cascade	RPS6KA1	RIPK2	MAPK3	IRAK3	IRAK4	FOS	CREB1	TIRAP	DUSP4	TLR1	TRAF6	PELI1	UBA52	UBE2V1	TLR6	DUSP6	DUSP7	CUL1	RELA	TLR2	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	BTK	LY96	CD14	TLR4	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	SIGIRR	PPP2R1A	MAPKAPK3	AGER	BTRC	SOCS1	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	CD36	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES%REACTOME%R-HSA-425393.2	Transport of inorganic cations anions and amino acids oligopeptides	SLC34A1	SLC9A2	SLC9A3	SLC9A4	SLC5A8	SLC9A5	SLC9A6	SLC9A7	SLC9A8	SLC9A9	SLC26A2	SLC26A1	SLC1A1	SLC1A2	SLC1A4	SLC1A5	SLC1A6	SLC1A7	SLC9A1	SLC5A5	SLC15A3	SLC38A3	SLC15A4	SLC38A2	SLC38A5	SLC38A4	SLC4A10	SLC16A10	SLC26A7	SLC26A9	SLC26A4	SLC26A3	SLC26A6	SLC7A11	SLC7A10	SLC36A1	SLC36A2	SLC32A1	SLC7A5	SLC25A18	SLC7A6	SLC7A7	SLC7A8	SLC25A10	SLC24A2	SLC24A1	SLC24A4	SLC24A3	SLC20A2	SLC43A2	SLC20A1	SLC43A1	SLC5A12	SLC3A2	SLC7A1	SLC7A3	SLC25A26	SLC25A29	SLC17A6	SLC17A7	SLC17A8	SLC17A1	SLC25A22	SLC36A4	CTNS	SLC8B1	SLC4A7	SLC8A3	SLC4A8	SLC4A9	SLC24A5	SLC6A20	SLC12A2	SLC12A3	SLC12A4	SLC12A5	SLC12A1	SLC12A6	SRI	SLC12A7	SLC6A19	SLC6A18	SLC6A15	SLC6A14	SLC6A12	SLC6A6	SLC1A3	SLC34A2	SLC7A9	SLC3A1	SLC17A5	AHCYL2	SLC4A1	SLC4A2	SLC4A3	SLC4A4	SLC4A5	SLC8A1	SLC8A2	SLC26A11	SLC34A3	SLC38A1	SLC15A1	SLC15A2	
REGULATION OF TP53 DEGRADATION%REACTOME%R-HSA-6804757.1	Regulation of TP53 Degradation	PHF20	CHEK2	MDM2	DAXX	MDM4	UBA52	CCNA2	CCNA1	PRR5	ATM	RNF34	PDPK1	MAPKAP1	UBB	RFFL	MTOR	UBC	AKT2	AKT3	MLST8	RPS27A	PPP2CA	AKT1	SGK1	PPP2CB	CDKN2A	RICTOR	PPP2R1A	CDK2	CCNG1	CDK1	USP7	PPP2R5C	PPP2R1B	USP2	TP53	
KSRP (KHSRP) BINDS AND DESTABILIZES MRNA%REACTOME%R-HSA-450604.2	KSRP (KHSRP) binds and destabilizes mRNA	EXOSC7	EXOSC6	AKT1	EXOSC5	EXOSC4	EXOSC9	EXOSC8	EXOSC3	EXOSC2	EXOSC1	MAPK14	MAPK11	KHSRP	DIS3	YWHAZ	DCP2	PARN	
INITIATION OF NUCLEAR ENVELOPE (NE) REFORMATION%REACTOME DATABASE ID RELEASE 74%2995383	Initiation of Nuclear Envelope (NE) Reformation	LBR	PPP2CA	LMNB1	VRK1	KPNB1	LEMD3	LEMD2	PPP2R1A	EMD	ANKLE2	PPP2R2A	SIRT2	CDK1	CCNB2	CCNB1	BANF1	
REGULATION OF SIGNALING BY NODAL%REACTOME DATABASE ID RELEASE 74%1433617	Regulation of signaling by NODAL	LEFTY2	LEFTY1	CER1	ACVR1B	ACVR1C	ACVR2B	CFC1	DAND5	ACVR2A	TDGF1	NODAL	
INSULIN EFFECTS INCREASED SYNTHESIS OF XYLULOSE-5-PHOSPHATE%REACTOME%R-HSA-163754.2	Insulin effects increased synthesis of Xylulose-5-Phosphate	TKT	TALDO1	
CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER%REACTOME%R-HSA-5674400.1	Constitutive Signaling by AKT1 E17K in Cancer	NR4A1	CDKN1A	CDKN1B	CREB1	FOXO1	MDM2	PRR5	RPS6KB2	PDPK1	MAPKAP1	TSC2	MTOR	AKT2	AKT3	MLST8	BAD	AKT1	AKT1S1	FOXO3	RICTOR	GSK3B	FOXO6	FOXO4	GSK3A	CASP9	CHUK	
BETA OXIDATION OF BUTANOYL-COA TO ACETYL-COA%REACTOME%R-HSA-77352.3	Beta oxidation of butanoyl-CoA to acetyl-CoA	ECHS1	ACSM3	ACSM6	HADH	ACADS	
CELL-CELL JUNCTION ORGANIZATION%REACTOME DATABASE ID RELEASE 74%421270	Cell-cell junction organization	JUP	CTNND1	F11R	CLDN2	CTNNB1	CLDN1	CDH9	PVR	CDH8	CDH7	CLDN22	CDH6	CDH5	CLDN20	CDH3	CLDN23	CLDN11	CLDN6	CLDN10	CLDN4	CLDN3	CLDN15	CLDN14	CLDN9	CLDN8	PARD3	CDH10	CLDN12	CLDN7	CDH11	CLDN19	CTNNA1	CDH12	CLDN18	CDH13	CLDN17	ANG	CLDN16	CDH17	CDH18	PARD6G	PARD6B	PARD6A	CDH24	CADM3	CADM1	CADM2	MPP5	INADL	SDK1	PVRL4	PVRL3	PVRL2	SDK2	PVRL1	CRB3	CDH15	CDH1	CDH4	CLDN5	CDH2	PRKCI	
DEFECTIVE GGT1 CAUSES GLUTATHIONURIA (GLUTH)%REACTOME%R-HSA-5579022.2	Defective GGT1 causes Glutathionuria (GLUTH)	GGT1	
ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12%REACTOME DATABASE ID RELEASE 74%392170	ADP signalling through P2Y purinoceptor 12	GNGT1	GNGT2	GNG12	GNG11	P2RY12	GNG13	GNB2	GNB1	GNG3	GNB4	GNG10	GNB3	GNG2	GNB5	GNG5	GNG4	GNG7	GNG8	GNAI3	GNAT3	GNAI1	GNAI2	
DEFECTIVE UGT1A4 CAUSES HYPERBILIRUBINEMIA%REACTOME DATABASE ID RELEASE 74%5579016	Defective UGT1A4 causes hyperbilirubinemia	UGT1A4	
LOSS OF PROTEINS REQUIRED FOR INTERPHASE MICROTUBULE ORGANIZATION FROM THE CENTROSOME%REACTOME DATABASE ID RELEASE 74%380284	Loss of proteins required for interphase microtubule organization from the centrosome	CSNK1E	DYNLL1	TUBG1	CKAP5	TUBA4A	HAUS2	HAUS1	AKAP9	CEP63	MAPRE1	SFI1	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	HAUS8	HAUS7	PRKAR2B	CEP70	CEP72	CEP192	PCNT	CEP76	CLASP1	CEP78	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	CEP57	YWHAE	CETN2	CEP164	CCP110	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	NINL	CEP290	YWHAG	CDK5RAP2	OFD1	HSP90AA1	CEP135	TUBB	CEP131	HAUS4	HAUS3	CSNK1D	HAUS6	HAUS5	
ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS%REACTOME DATABASE ID RELEASE 74%181431	Acetylcholine binding and downstream events	CHRNA5	CHRNA4	CHRNA7	CHRNA6	CHRNA9	CHRND	CHRNG	CHRNE	CHRNA1	CHRNB2	CHRNA3	CHRNB4	CHRNB3	CHRNA2	
ACTIVATION OF RAC1%REACTOME DATABASE ID RELEASE 74%428540	Activation of RAC1	PAK3	PAK2	ROBO1	PAK7	PAK6	PAK4	NCK2	RAC1	SLIT2	SOS1	NCK1	SOS2	PAK1	
INTEGRIN CELL SURFACE INTERACTIONS%REACTOME DATABASE ID RELEASE 74%216083	Integrin cell surface interactions	ITGB5	TNC	ICAM4	ICAM5	ITGAE	ICAM1	COMP	IBSP	ITGAX	ITGB8	COL9A1	ITGB7	COL9A3	ITGB6	COL9A2	COL18A1	ITGA3	ITGAD	ITGA8	ITGAL	ITGA7	ITGA6	CD47	F11R	VTN	JAM2	JAM3	VCAM1	ITGA10	ITGA11	FBN1	KDR	ITGA2B	LUM	CD44	SPP1	AGRN	ITGA4	COL4A2	COL4A1	COL4A4	THBS1	COL4A3	ITGB1	FN1	ITGA5	COL16A1	ITGB3	CDH1	FGB	FGA	BSG	ITGAV	FGG	ITGA2	ITGA1	COL23A1	HSPG2	ITGAM	ITGB2	ITGA9	ICAM2	ICAM3	COL13A1	
SHC-MEDIATED CASCADE:FGFR2%REACTOME DATABASE ID RELEASE 74%5654699	SHC-mediated cascade:FGFR2	FGF20	FGF1	FGF23	FGF2	FGF22	FGF3	FGF4	FGF16	FGF6	NRAS	FGF7	FGF9	SOS1	HRAS	FGF18	FGF10	
SYNTHESIS OF PIPS IN THE NUCLEUS%REACTOME%R-HSA-8847453.2	Synthesis of PIPs in the nucleus	TMEM55B	PIP4K2A	PIP4K2B	PIP4K2C	
RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES (TREGS)%REACTOME%R-HSA-8877330.1	RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	IL2	CR1	CBFB	CTLA4	TNFRSF18	IL2RA	NFATC2	FOXP3	IFNG	RUNX1	
L1CAM INTERACTIONS%REACTOME DATABASE ID RELEASE 74%373760	L1CAM interactions	SCN4A	SCN4B	LAMA1	CNTN1	DNM1	DNM2	DNM3	SCN7A	L1CAM	ALCAM	RANBP9	SCN11A	KIF4B	KIF4A	NCAN	LYPLA2	MAPK1	ITGA2B	RAC1	NRCAM	SCN10A	MAP2K1	MAP2K2	RDX	SDCBP	CHL1	GAP43	DCX	ITGB3	CNTNAP1	ITGAV	ITGA2	ITGA1	ITGA9	RPS6KA3	RPS6KA6	RPS6KA2	RPS6KA1	MAPK3	NCAM1	EPHB2	SCN1B	SCN1A	LAMC1	EGFR	SHTN1	KCNQ2	KCNQ3	ITGA10	AP2A1	AP2A2	SCN3B	AP2M1	SCN3A	HSPA8	CLTC	CLTA	SCN2A	SCN2B	NRP1	NRP2	VAV2	AP2S1	LAMB1	CSNK2A1	SPTAN1	ANK2	ANK3	CSNK2A2	ANK1	SPTB	SPTBN4	SPTBN5	SPTA1	NFASC	AP2B1	SPTBN1	CSNK2B	SPTBN2	RPS6KA4	SCN9A	ITGB1	SH3GL2	ITGA5	SCN8A	EZR	DLG1	DLG3	DLG4	CNTN6	MSN	CNTN2	SCN5A	DPYSL2	NUMB	PAK1	RPS6KA5	
CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2%REACTOME%R-HSA-9634285.1	Constitutive Signaling by Overexpressed ERBB2	ERBB2	NRAS	HSP90AA1	CDC37	SOS1	ERBB2IP	HRAS	PTPN12	SHC1	
AFLATOXIN ACTIVATION AND DETOXIFICATION%REACTOME%R-HSA-5423646.3	Aflatoxin activation and detoxification	GGT7	ACY3	CYP1A2	GGT6	ACY1	GGT1	MGST3	MGST1	MGST2	DPEP2	AKR7L	DPEP1	AKR7A2	DPEP3	AKR7A3	CYP3A4	GGT5	CYP3A5	CYP2A13	
INHIBITION OF VOLTAGE GATED CA2+ CHANNELS VIA GBETA GAMMA SUBUNITS%REACTOME DATABASE ID RELEASE 74%997272	Inhibition of voltage gated Ca2+ channels via Gbeta gamma subunits	KCNJ5	KCNJ6	GABBR1	KCNJ10	KCNJ12	KCNJ9	KCNJ15	GNG12	KCNJ16	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	GNGT1	GNGT2	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	KCNJ2	KCNJ3	KCNJ4	GABBR2	
ARACHIDONIC ACID METABOLISM%REACTOME DATABASE ID RELEASE 74%2142753	Arachidonic acid metabolism	LTA4H	CYP2C9	CYP1B1	CYP2C8	PLA2G4A	CYP1A2	CYP1A1	GPX2	CYP2U1	MAPKAPK2	ABCC1	PTGS2	TBXAS1	GGT1	DPEP2	DPEP1	DPEP3	PTGES3	GGT5	PON3	GPX1	GPX4	FAAH	PON2	CYP4A22	ALOX5AP	HPGDS	PON1	PTGDS	LTC4S	CBR1	PTGIS	FAAH2	PTGR1	PTGR2	PTGES	ALOX12B	CYP4F22	PTGS1	CYP4A11	FAM213B	AWAT1	ALOXE3	PTGES2	CYP2C19	EPHX2	CYP4F2	CYP4F3	AKR1C3	CYP4B1	CYP4F11	CYP4F8	CYP8B1	ALOX15B	CYP2J2	ALOX15	HPGD	ALOX12	ALOX5	
DEFECTIVE GSS CAUSES GLUTATHIONE SYNTHETASE DEFICIENCY (GSS DEFICIENCY)%REACTOME DATABASE ID RELEASE 74%5579006	Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)	GSS	
SIGNALING BY FGFR2 AMPLIFICATION MUTANTS%REACTOME%R-HSA-2023837.1	Signaling by FGFR2 amplification mutants	FGFR2	
NEF AND SIGNAL TRANSDUCTION%REACTOME%R-HSA-164944.2	Nef and signal transduction	PAK2	DOCK2	FYN	HCK	LCK	ELMO1	RAC1	
PHYSIOLOGICAL FACTORS%REACTOME%R-HSA-5578768.1	Physiological factors	NKX2-5	KAT2B	NPPC	TBX5	NPR1	NPR2	GATA4	CORIN	HIPK1	WWTR1	HIPK2	NPPA	
TGF-BETA RECEPTOR SIGNALING IN EMT (EPITHELIAL TO MESENCHYMAL TRANSITION)%REACTOME DATABASE ID RELEASE 74%2173791	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	RPS27A	ARHGEF18	CGN	PRKCZ	PARD3	RHOA	UBA52	SMURF1	TGFB1	F11R	TGFBR1	TGFBR2	UBB	PARD6A	FKBP1A	UBC	
INLB-MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL%REACTOME%R-HSA-8875360.2	InlB-mediated entry of Listeria monocytogenes into host cell	SH3KBP1	RPS27A	STAM	HGS	EPS15	UBA52	SH3GL1	SH3GL3	STAM2	CBL	SH3GL2	UBB	UBC	MET	
N-GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE%REACTOME%R-HSA-532668.2	N-glycan trimming in the ER and Calnexin Calreticulin cycle	PRKCSH	GANAB	VCP	UBA52	EDEM2	MOGS	SEL1L	MAN1B1	UBB	EDEM1	UBXN1	UBC	SYVN1	NGLY1	RNF139	MLEC	RPS27A	UGGT2	UGGT1	RNF185	PDIA3	EDEM3	AMFR	MARCH6	RAD23B	RNF103	PSMC1	TRIM13	CALR	ENGASE	CANX	DERL1	DERL2	RNF5	OS9	
DISEASES ASSOCIATED WITH O-GLYCOSYLATION OF PROTEINS%REACTOME%R-HSA-3906995.2	Diseases associated with O-glycosylation of proteins	ADAMTS16	ADAMTS18	NOTCH1	ADAMTS4	ADAMTS5	ADAMTS1	ADAMTS2	ADAMTS3	GALNT12	MUCL1	MUC17	MUC5B	ADAMTS8	MUC3A	MUC5AC	ADAMTS9	MUC1	ADAMTS14	MUC7	MUC12	MUC13	MUC15	MUC20	MUC4	MUC21	MUC6	NOTCH3	NOTCH4	POMT2	SPON2	THBS1	SEMA5B	SPON1	THSD7B	POMT1	LFNG	ADAMTSL1	C1GALT1C1	DAG1	ADAMTSL4	ADAMTSL3	ADAMTSL2	THSD7A	ADAMTS6	ADAMTS7	GALNT3	SBSPON	POMGNT1	ADAMTS20	B3GLCT	THBS2	CFP	ADAMTS12	THSD1	ADAMTS10	THSD4	ADAMTS15	ADAMTS13	ADAMTS19	LARGE	ADAMTS17	C1GALT1	B4GAT1	SEMA5A	NOTCH2	
DEFECTIVE CYP24A1 CAUSES HYPERCALCEMIA, INFANTILE (HCAI)%REACTOME%R-HSA-5579010.1	Defective CYP24A1 causes Hypercalcemia, infantile (HCAI)	CYP24A1	
TRAFFICKING OF MYRISTOYLATED PROTEINS TO THE CILIUM%REACTOME DATABASE ID RELEASE 74%5624138	Trafficking of myristoylated proteins to the cilium	UNC119B	RP2	ARL3	NPHP3	NPHP3-ACAD11	CYS1	
DEFECTIVE F8 CLEAVAGE BY THROMBIN%REACTOME%R-HSA-9672391.1	Defective F8 cleavage by thrombin	F2	F8	VWF	
LIGAND-RECEPTOR INTERACTIONS%REACTOME%R-HSA-5632681.1	Ligand-receptor interactions	IHH	CDON	SHH	HHIP	PTCH1	BOC	GAS1	DHH	
SIGNALING BY LIGAND-RESPONSIVE EGFR VARIANTS IN CANCER%REACTOME DATABASE ID RELEASE 74%5637815	Signaling by Ligand-Responsive EGFR Variants in Cancer	RPS27A	UBA52	SHC1	EGF	GAB1	CBL	EGFR	NRAS	HSP90AA1	CDC37	PLCG1	SOS1	HRAS	UBB	PIK3R1	PIK3CA	UBC	
NFG AND PRONGF BINDS TO P75NTR%REACTOME%R-HSA-205017.1	NFG and proNGF binds to p75NTR	NGF	NGFR	
APOPTOTIC EXECUTION PHASE%REACTOME DATABASE ID RELEASE 74%75153	Apoptotic execution phase	PAK2	LMNB1	CASP6	PRKCQ	ADD1	BIRC2	CTNNB1	PRKCD	CLSPN	CASP3	BMX	H1F0	STK24	STK26	HMGB2	HIST1H1D	KPNA1	HIST1H1E	DNM1L	KPNB1	HIST1H1A	HIST1H1B	HIST1H1C	DFFB	DFFA	OCLN	DBNL	GAS2	MAPT	PLEC	TJP1	SATB1	BCAP31	GSN	FNTA	ACIN1	VIM	TJP2	CASP7	SPTAN1	CASP8	ROCK1	PKP1	CDH1	DSP	DSG1	DSG2	DSG3	HMGB1	PTK2	APC	
DOPAMINE RECEPTORS%REACTOME%R-HSA-390651.2	Dopamine receptors	DRD1	DRD2	DRD3	DRD4	DRD5	
FORMATION OF A POOL OF FREE 40S SUBUNITS%REACTOME DATABASE ID RELEASE 74%72689	Formation of a pool of free 40S subunits	UBA52	RPS27A	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	EIF1AX	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	EIF3M	EIF3K	EIF3L	EIF3I	EIF3J	EIF3G	EIF3H	EIF3E	RPL22L1	EIF3F	FAU	EIF3C	EIF3D	EIF3A	RPL26L1	EIF3B	
ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION%REACTOME%R-HSA-2730905.2	Role of LAT2 NTAL LAB on calcium mobilization	LAT2	FYN	IGKV2-28	IGKV1-12	IGKV3D-20	IGKV2D-28	IGKV4-1	GAB2	IGHE	PIK3CB	IGKV2D-30	PDPK1	IGKV3-11	LYN	IGKV5-2	SOS1	PIK3R2	PIK3R1	SYK	PIK3CA	
REGULATION OF PAK-2P34 ACTIVITY BY PS-GAP RHG10%REACTOME%R-HSA-211728.2	Regulation of PAK-2p34 activity by PS-GAP RHG10	PAK2	ARHGAP10	
GAP-FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG-NER%REACTOME DATABASE ID RELEASE 74%5696397	Gap-filling DNA repair synthesis and ligation in GG-NER	POLK	XRCC1	LIG3	UBA52	UBB	UBC	RPS27A	RFC5	RFC3	PCNA	RPA1	RFC4	RPA2	RFC1	LIG1	RFC2	POLE4	POLD3	POLD4	RPA3	POLE2	POLD1	POLE3	POLD2	POLE	
RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION%REACTOME%R-HSA-8936459.1	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	ZFPM1	HIST2H2AC	H2AFJ	GATA1	SETD1B	SETD1A	TNRC6C	MOV10	AGO3	H2AFZ	NFE2	AGO4	H2AFX	H2AFV	AGO1	HIST2H2BE	HIST4H4	TNRC6A	TNRC6B	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	ITGA2B	SIN3A	HDAC1	ASH2L	KMT2D	KMT2A	KMT2C	MYL9	KMT2E	KMT2B	SIN3B	CBFB	PRKCQ	PRMT1	WDR5	PRMT6	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	NR4A3	HIST1H2AJ	RBBP5	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	THBS1	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	RUNX1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	DPY30	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	GP1BA	KAT2B	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	PF4	HIST2H2AA4	
PERVASIVE DEVELOPMENTAL DISORDERS%REACTOME DATABASE ID RELEASE 74%9005895	Pervasive developmental disorders	CAMK4	TBL1X	HDAC1	TBL1XR1	SIN3A	HDAC3	PRKACA	NCOR2	NCOR1	GPS2	
BBSOME-MEDIATED CARGO-TARGETING TO CILIUM%REACTOME DATABASE ID RELEASE 74%5620922	BBSome-mediated cargo-targeting to cilium	MKKS	ARL6	BBIP1	SSTR3	MCHR1	RAB3IP	LZTFL1	TTC8	SMO	BBS10	BBS12	TCP1	BBS9	BBS7	CCT8	BBS5	BBS4	CCT5	CCT4	CCT3	BBS2	BBS1	CCT2	
RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION%REACTOME DATABASE ID RELEASE 74%8949275	RUNX3 Regulates Immune Response and Cell Migration	ITGAL	CBFB	RUNX3	ITGA4	SPP1	
STAT6-MEDIATED INDUCTION OF CHEMOKINES%REACTOME DATABASE ID RELEASE 74%3249367	STAT6-mediated induction of chemokines	STAT6	TMEM173	TBK1	
INCRETIN SYNTHESIS, SECRETION, AND INACTIVATION%REACTOME%R-HSA-400508.1	Incretin synthesis, secretion, and inactivation	CDX2	GRP	GPR119	DPP4	SPCS3	GATA4	GIP	SPCS2	ISL1	SPCS1	FFAR4	GNG13	FFAR1	GCG	SEC11A	SEC11C	LEP	GNB3	CTNNB1	PAX6	GNAT3	TCF7L2	PCSK1	
SIGNALING BY RAF1 MUTANTS%REACTOME%R-HSA-9656223.1	Signaling by RAF1 mutants	MAPK3	RAF1	CSK	CAMK2G	SRC	RAP1B	RAP1A	MARK3	YWHAB	NRAS	FN1	CNKSR2	HRAS	APBB1IP	CNKSR1	ITGB3	ARRB1	ARAF	ARRB2	MAPK1	FGB	FGA	ITGA2B	VWF	CAMK2A	KSR1	FGG	TLN1	KSR2	IQGAP1	JAK2	BRAF	MAP2K1	MAP2K2	CAMK2B	VCL	CAMK2D	
SYNTHESIS OF PIPS AT THE ER MEMBRANE%REACTOME DATABASE ID RELEASE 74%1483248	Synthesis of PIPs at the ER membrane	PI4K2B	MTMR2	SACM1L	SBF1	
DUAL INCISION IN GG-NER%REACTOME DATABASE ID RELEASE 74%5696400	Dual Incision in GG-NER	POLK	UBA52	XPA	UBB	PARP2	CHD1L	CUL4A	DDB1	UBC	ERCC5	CUL4B	RPS27A	DDB2	RBX1	RFC5	RFC3	PCNA	RPA1	RFC4	RPA2	GTF2H1	RFC1	GTF2H2	GTF2H3	PARP1	RFC2	GTF2H4	POLE4	POLD3	GTF2H5	POLD4	RPA3	POLE2	POLD1	ERCC3	POLE3	POLD2	POLE	ERCC2	ERCC4	ERCC1	
REGULATION OF ACTIVATED PAK-2P34 BY PROTEASOME MEDIATED DEGRADATION%REACTOME DATABASE ID RELEASE 74%211733	Regulation of activated PAK-2p34 by proteasome mediated degradation	PSMA6	PSMA3	PSMA4	PAK2	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
AMINO ACID CONJUGATION%REACTOME%R-HSA-156587.1	Amino Acid conjugation	ACSM2B	GLYATL3	GLYATL2	GLYATL1	ACSM1	ACSM2A	ACSM5	ACSM4	GLYAT	
DEFECTIVE SLC22A12 CAUSES RENAL HYPOURICEMIA 1 (RHUC1)%REACTOME DATABASE ID RELEASE 74%5619071	Defective SLC22A12 causes renal hypouricemia 1 (RHUC1)	SLC22A12	
VESICLE-MEDIATED TRANSPORT%REACTOME DATABASE ID RELEASE 74%5653656	Vesicle-mediated transport	SH3D19	SH3KBP1	RALA	DYNLL1	SGIP1	DNAJC6	SEC22A	SEC22C	SEC23A	LRP1	DENND3	LRP2	RAB21	CFTR	FCHO1	FCHO2	UBA52	UBQLN1	OPTN	UBQLN2	PAFAH1B1	SEC24B	SEC24A	HIP1R	DYNC1I2	TPD52L1	DCTN2	RAB10	NECAP2	DCTN3	NECAP1	RAB14	ST5	SYT11	RAB12	UBB	RAB13	SEC24D	SEC24C	SPARC	UBC	RINL	TBC1D10C	TBC1D10A	RPS27A	TBC1D10B	AGFG1	LMAN1L	RIN3	ULK1	RIN1	RIN2	DYNC1H1	LMAN2L	STXBP3	SCFD1	SNX2	GJA10	SNX9	APOA1	SNX5	TBC1D8B	MSR1	RAB39B	RAB27A	RAB27B	PUM1	SNAP91	MARCO	MON1A	MON1B	C2CD5	HIP1	GDI1	CTSZ	GDI2	AP4E1	STAB2	MIA2	MIA3	JCHAIN	MAP1LC3B	STAB1	CTSC	RAB8B	HBA2	HBA1	RAB33A	GAK	CTTN	RAB7B	RHOQ	RABGAP1	STX17	ALS2CL	SORT1	RAB11B	SEC23IP	YIPF6	TRIP10	SCARB2	DENND5B	TRAPPC12	TRAPPC11	SLC2A4	CHM	DENND5A	TRAPPC13	SBF2	TRAPPC2L	SCARA5	OCRL	TBC1D20	TBC1D24	CD163	TBC1D25	AMPH	DENND6B	DENND6A	TBC1D13	PACSIN2	PACSIN3	TBC1D14	TBC1D17	TBC1D15	PACSIN1	TBC1D16	SYT2	DENND4B	SYT1	DENND4A	CCZ1	ASPSCR1	SSC5D	SYT9	AP4B1	SYT8	ACBD3	IL7R	PICALM	SLC2A8	SCARF1	EPN1	EPN2	TBC1D1	TRAPPC6A	TBC1D2	RABEP1	TBC1D3	TBC1D4	ALS2	TRAPPC6B	TBC1D7	DNASE2	COLEC12	CLVS2	REPS2	CLVS1	REPS1	DTNBP1	YWHAB	YWHAZ	HSPA8	ARPC1A	WASL	CD3D	ACTR3	GNS	ACTR2	CD4	MYO5A	ARPC4	ARPC5	HSPH1	MYO1C	ARPC2	ARPC3	AVP	PLA2G6	KIF3A	EREG	BTC	RAB7A	TGFA	TSG101	VPS4B	VPS4A	MVB12B	MVB12A	VPS36	VTA1	VPS37C	VPS37D	AREG	VPS37A	VPS37B	STAM	SNF8	PLA2G4A	HGS	CHMP2B	CHMP2A	CHMP4C	CHMP4B	UBAP1	CHMP3	CHMP4A	CHMP6	CHMP7	STAM2	VPS25	GRIA1	VPS28	CHMP5	AGPAT3	HBEGF	EPGN	AP3B1	ARRB1	ARRB2	EPS15	SH3GL1	CALR	CD3G	CLTC	CLTA	GOLGA2	SPTAN1	ANK2	ANK3	ANK1	SPTB	SPTBN4	SPTBN5	COLEC11	INS	SPTA1	CD59	CD55	SPTBN1	SPTBN2	TMEM115	GOLGB1	FOLR1	BET1	APP	MASP1	USP6NL	SCOC	SYS1	KDELR1	GOLIM4	GCC2	HSP90B1	GCC1	RAB43	RAB41	GOLGA4	GOLGA5	KIF5B	KIF5A	GOLGA1	ARFIP2	KIF21A	KIF21B	KIFAP3	ITSN1	NSF	COG8	COG7	COG6	COG5	COG4	COG3	CD36	COG2	COG1	RINT1	DYNC1LI1	RAB30	DYNC1LI2	RAB36	KIF16B	ZW10	DNM1	KDELR2	DNM2	KIF20A	KDELR3	DNM3	KIF20B	SEC13	COPB2	COPA	TMED10	PIP5K1C	COPB1	RHOBTB3	ARL1	KLC1	TGOLN2	KLC4	KLC3	KLC2	GORASP1	KIF3B	RACGAP1	MAN2A2	MAN2A1	VTI1A	RAB1A	KIF3C	RAB6A	RAB6B	SURF4	RAB1B	RAB39A	USO1	M6PR	IGF2R	KIF18A	KIF18B	SAA1	ALPP	KIF4B	KIF4A	COPE	ARF3	ARF4	ARF1	KIF11	BICD1	USE1	RABEPK	BICD2	KIF15	KIF19	CAPZB	MAN1A2	KIF13B	TMED3	KIF1C	TMED2	MAN1A1	KIF1B	KIF1A	TMED7	SNAP29	TMED9	NAA30	KIF25	COPZ2	KIF23	KIF22	ARFGAP3	KIF6	DYNLL2	BET1L	ARFGAP1	KIF27	COPZ1	RAB33B	ARFGAP2	KIF9	KIFC2	KIF2A	KIFC1	SBF1	PLIN3	NAA35	KIF2C	NAA38	KIF2B	SEC22B	VAMP4	PAFAH1B3	ARF5	PAFAH1B2	CLTCL1	VAMP3	DCTN6	NAPA	DCTN5	NAPB	NBAS	TMF1	STX16	DCTN1	EXOC8	DCTN4	EXOC7	GOSR2	RAB3IP	STX18	GOSR1	NAPG	STX10	RAB11A	CYTH3	CYTH2	EXOC4	ARFRP1	CYTH4	EXOC3	CUX1	EXOC6	VPS51	VPS53	EXOC5	VPS52	BNIP1	EXOC2	MAN1C1	EXOC1	STX6	STX5	VPS54	YKT6	CYTH1	DYNC1I1	RIC1	GALNT2	GALNT1	GBF1	ARCN1	RGP1	CENPE	CAPZA3	KIF26A	CAPZA1	KIF26B	CAPZA2	RAB18	RAB3GAP2	IGKV2-28	IGKV1-12	TRIP11	IGKV3D-20	RAB9A	COPG2	VPS45	IGKV2D-28	PREB	COPG1	IGKV4-1	ACTR10	RAB3GAP1	RAB9B	IGKV2D-30	IGKV3-11	SEC31A	IGKV5-2	HYOU1	AP1G1	AP1B1	AP1S2	AP1S1	AP1S3	AP1M2	AP1M1	SH3GL2	AKT2	AKT3	AKT1	WNT5A	TFRC	FTH1	FZD4	FTL	NEDD8	ADRBK1	RAB5A	TF	PIK3C2A	HBB	RAC1	COL1A1	COL3A1	COL1A2	COL4A2	PRKAA2	COL4A1	PRKAG1	CLTB	COL7A1	PRKAG2	PRKAG3	MYH9	PRKAB2	TSC2	TSC1	PRKAB1	YWHAQ	SFN	YWHAH	ITSN2	FNBP1L	RABGEF1	GJA1	TFG	GJA3	GJA5	GJA4	GJA9	GJA8	GABARAPL2	FNBP1	SYTL1	GAPVD1	EGF	BIN1	AGTR1	CHRM2	CBL	COPS7B	EGFR	COPS7A	HPR	GABARAP	BLOC1S4	GJC1	HPX	BLOC1S6	GJC2	BLOC1S1	ADRB2	BLOC1S3	AP2A1	MYO6	IGHA1	SNAPIN	CCZ1B	AP2A2	LNPEP	GJB2	GJB1	GJB4	GJB3	GJB6	LDLRAP1	GJB5	AP2M1	GJB7	DENND1C	DENND1B	SERPINA1	DENND1A	STON1	STON2	CLINT1	AP3S1	TJP1	SLC18A3	DENND2D	DENND2C	DENND2A	RAB3IL1	EPS15L1	TACR1	SAR1B	VAMP8	GJD2	GJD4	VAMP7	GJD3	VAMP2	ARF6	GPS1	AP2S1	GGA2	LMAN1	APOE	GGA1	APOB	GGA3	LDLR	ADRBK2	LMAN2	STX4	CHML	APOL1	TRAPPC10	SNX18	RAB3A	HP	TPD52	AP2B1	RALGAPA2	RAB32	RAB31	ALB	RALGAPB	RAB35	RAB38	DVL2	RAB5B	RAB5C	AP4S1	KIAA0319	TXNDC5	ANKRD28	TRAPPC2	SEC16B	TRAPPC3	RAB4A	TRAPPC1	TOR1A	AVPR2	YWHAE	ANKRD27	AMBP	TRAPPC4	SEC16A	TRAPPC5	ACTR1A	HPS1	HPS4	TRAPPC8	TRAPPC9	SYNJ2	TOR1B	COPS4	COPS3	COPS6	DAB2	SH3GL3	COPS5	YWHAG	CNIH1	RAB8A	SYNJ1	COPS2	CPD	F5	SCGB3A2	HSP90AA1	AAK1	COPS8	CNIH2	F8	CNIH3	MCFD2	SNAP23	AP4M1	PPP6C	AP1G2	CSNK1D	PPP6R1	PPP6R3	
SUMOYLATION OF DNA REPLICATION PROTEINS%REACTOME DATABASE ID RELEASE 74%4615885	SUMOylation of DNA replication proteins	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	RANGAP1	TOP2A	INCENP	BIRC5	NUP50	TOP2B	AURKB	AURKA	SUMO3	NUP205	SUMO2	NUP54	POM121	PIAS4	PIAS3	TOP1	AAAS	NUP160	NUP85	TPR	NUP88	NUP43	RAE1	PCNA	RANBP2	NUP155	NUP35	NUPL2	NUP37	NUP107	SUMO1	NUP153	NUP188	UBE2I	CDCA8	
SYNTHESIS, SECRETION, AND INACTIVATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1)%REACTOME%R-HSA-381771.2	Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	CDX2	GRP	GPR119	DPP4	SPCS3	SPCS2	SPCS1	FFAR4	GNG13	FFAR1	GCG	SEC11A	SEC11C	LEP	GNB3	CTNNB1	PAX6	GNAT3	TCF7L2	PCSK1	
REGULATION OF COMPLEMENT CASCADE%REACTOME%R-HSA-977606.5	Regulation of Complement cascade	CR1	IGKV2-28	IGKV1-12	IGKV3D-20	ELANE	IGKV2D-28	IGKV4-1	IGKV2D-30	VTN	IGKV3-11	IGKV5-2	C3AR1	CD81	C4BPA	C4BPB	C8B	C8A	CLU	C8G	CR2	CD46	CPB2	CFH	C5AR2	CFI	C5AR1	CPN2	CPN1	C5	C6	C7	CD19	C1QB	C9	CFHR2	C1QA	CFHR1	CFHR4	CD59	CFHR3	CD55	CFHR5	C1S	C1R	C4B_2	C2	C3	C4B	IGHG4	C4A	IGHG1	IGHG2	CFB	PROS1	C1QC	F2	SERPING1	
O-LINKED GLYCOSYLATION OF MUCINS%REACTOME DATABASE ID RELEASE 74%913709	O-linked glycosylation of mucins	B3GNT4	B3GNT3	B3GNT2	CHST4	B4GALT6	B4GALT5	GCNT1	GCNT3	ST3GAL4	GCNT4	GCNT7	GALNT7	ST3GAL1	GALNT6	ST3GAL2	GALNT5	ST3GAL3	GALNT4	ST6GAL1	A4GNT	GALNTL5	GALNTL6	ST6GALNAC3	ST6GALNAC4	GALNT12	MUCL1	MUC17	MUC5B	MUC3A	MUC5AC	MUC1	MUC7	MUC12	MUC13	MUC15	MUC20	MUC4	MUC21	MUC6	C1GALT1C1	GALNT3	C1GALT1	GALNT11	GALNT14	GALNT13	GALNT16	GALNT15	GALNT18	B3GNTL1	GALNT10	GALNT9	GALNT8	B3GNT9	GALNT2	WBSCR17	GALNT1	B3GNT8	B3GNT7	B3GNT6	ST6GALNAC2	B3GNT5	
HYPUSINYLATION%REACTOME%R-HSA-204626.1	Hypusinylation	EIF5A	EIF5A2	DHPS	DOHH	
TOXICITY OF BOTULINUM TOXIN TYPE D (BONT D)%REACTOME DATABASE ID RELEASE 74%5250955	Toxicity of botulinum toxin type D (BoNT D)	VAMP1	SV2C	SV2B	VAMP2	SV2A	
VIRUS ASSEMBLY AND RELEASE%REACTOME%R-HSA-168268.3	Virus Assembly and Release	CALR	CANX	
HDACS DEACETYLATE HISTONES%REACTOME%R-HSA-3214815.3	HDACs deacetylate histones	HIST2H2AC	PHF21A	HDAC8	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HDAC10	HIST1H2BK	TBL1X	HIST2H4A	HIST2H2AB	HIST2H4B	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	HIST1H2AI	HMG20B	HIST1H2AH	HIST1H2AK	HIST2H2BF	HIST3H2A	HDAC2	HDAC1	HIST1H2AE	HIST1H2AD	HDAC3	HIST3H2BB	HIST1H2AC	HIST1H2AB	ARID4A	HIST1H2AJ	ARID4B	TBL1XR1	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	SAP30	HIST1H2BG	BRMS1	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	SAP30L	SAP18	SUDS3	CHD4	CHD3	HIST1H3J	NCOR2	REST	NCOR1	GPS2	MTA1	HIST1H3A	RBBP4	HIST1H3F	HIST1H3G	HIST1H3H	RBBP7	HIST1H3I	MTA2	HIST1H3B	MTA3	HIST1H3C	HIST1H3D	MBD3	HIST1H3E	HIST1H4K	HIST1H4L	GATAD2B	GATAD2A	KDM1A	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
TRANSMISSION ACROSS CHEMICAL SYNAPSES%REACTOME DATABASE ID RELEASE 74%112315	Transmission across Chemical Synapses	SLC1A1	SLC1A2	SLC1A6	SLC1A7	SLC38A2	PRKAR2B	AKAP5	SLC32A1	MAPK1	ARHGEF9	MAOA	SLC17A7	GLS	SYT1	GLS2	STX1A	SLC22A2	SLC22A1	SLC6A13	SLC6A12	SLC6A11	HSPA8	SLC6A1	SLC6A3	SLC18A2	GIT1	SRC	PDPK1	CHAT	CHRNA1	CHRNB2	CHRNA3	CHRNB4	PRKACG	CHRNB3	PRKACB	CHRNA2	GNGT1	CHRNA5	CHRNA4	CHRNA7	GNGT2	CHRNA6	ADCY9	CHRNA9	PRKAR1B	CHRND	CHRNG	DLG1	PRKAR1A	CHRNE	DLG3	ACTN2	PLCB3	DLG4	GRIK5	PLCB1	GRIK3	PLCB2	PRKAR2A	GRIK4	CAMK2A	GRIK1	GRIK2	NCALD	ACHE	GNG3	GNG10	GNG2	GNG5	GNG4	GRIN2B	GNG7	GNG8	GRIN2D	ADCY4	ADCY3	ADCY2	ADCY1	ADCY8	ADCY7	NEFL	ADCY6	CREB1	ADCY5	GNG12	GNG11	GNG13	KIF17	GNB2	NRGN	PRKCG	CASK	GNB1	GRIA1	GRIA2	GNB4	LIN7A	GNB3	LIN7C	GNB5	PPM1E	LIN7B	PPM1F	CAMKK1	CAMKK2	GRIN2A	BCHE	LRRC7	GRIA3	GRIA4	GRIN2C	GRIN3B	GAD1	GRIN3A	GAD2	NBEA	CAMK4	APBA1	CAMK1	GRIN1	RAC1	KCNJ2	KCNJ3	KCNJ4	GABBR2	KCNJ5	KCNJ6	GABBR1	KCNJ10	KCNJ12	KCNJ9	KCNJ15	KCNJ16	PRKAA1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	DLG2	PRKAB2	PRKAB1	RASGRF2	RASGRF1	ABAT	ARL6IP5	GLUL	UNC13B	CACNA2D3	CACNA2D2	GABRG3	GABRG2	SLC5A7	NRG1	EPB41L1	TSPAN7	GABRB3	GABRB2	GABRB1	SLC6A4	GABRR3	GABRR2	GABRR1	SYN3	SYN1	ALDH5A1	RPS6KA3	PICK1	CAMK2B	RPS6KA6	GLRA1	CAMK2D	RPS6KA2	GLRA2	CACNB1	RPS6KA1	GLRA3	CACNB2	GABRA2	CACNB3	MAPK3	GABRQ	CACNB4	GABRA1	GABRA6	CAMK2G	GABRA5	GABRA4	GABRA3	GRIP1	RIMS1	BZRAP1	MDM2	PPFIA1	PPFIA4	PPFIA3	PPFIA2	NAAA	CACNA1B	CACNA1A	CPLX1	NRAS	CACNA1E	GNAL	ALDH2	NPTN	HRAS	HTR3E	HTR3C	HTR3D	HTR3A	SNAP25	HTR3B	GNAT3	AP2A1	LRTOMT	MYO6	DNAJC5	GLRB	KPNA2	PRKX	SLC18A3	GNAI3	VAMP2	GNAI1	GNAI2	CACNG8	PRKCB	PRKCA	COMT	CACNG2	CACNG3	CACNG4	RAB3A	SLC1A3	PRKACA	NSF	SLC38A1	
FOXO-MEDIATED TRANSCRIPTION%REACTOME%R-HSA-9614085.2	FOXO-mediated transcription	CDKN1A	CDKN1B	BCL6	FOXO1	BCL2L11	FBXO32	PCBP4	PLXNA4	PPARGC1A	RBL2	YWHAB	SOD2	BTG1	TRIM63	ABCA6	GADD45A	YWHAZ	SIRT3	TXNIP	TXN	PINK1	FOXO3	PCK1	SIN3A	NPY	HDAC2	HDAC1	AGRP	SIRT1	FOXG1	CITED2	FASLG	NR3C1	IGFBP1	NFYA	INS	NFYB	NFYC	KLF4	MSTN	DDIT3	SMAD4	SREBF1	SMAD2	SMAD3	STK11	CCNG2	BBC3	AKT2	G6PC	AKT3	YWHAQ	AKT1	SFN	POMC	CAV1	CAT	RETN	GCK	YWHAG	FOXO6	KAT2B	FOXO4	ATXN3	CREBBP	EP300	
PHOSPHORYLATION OF PROTEINS INVOLVED IN G1 S TRANSITION BY ACTIVE CYCLIN E:CDK2 COMPLEXES%REACTOME DATABASE ID RELEASE 74%69200	Phosphorylation of proteins involved in G1 S transition by active Cyclin E:Cdk2 complexes	CCNE2	CCNE1	RB1	CDK2	
DEFECTIVE SLC22A5 CAUSES SYSTEMIC PRIMARY CARNITINE DEFICIENCY (CDSP)%REACTOME%R-HSA-5619053.1	Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP)	SLC22A5	
MET ACTIVATES PTPN11%REACTOME DATABASE ID RELEASE 74%8865999	MET activates PTPN11	GAB1	PTPN11	HGF	MET	
THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT%REACTOME%R-HSA-8852276.2	The role of GTSE1 in G2 M progression after G2 checkpoint	PSMA6	PSMA3	CDKN1A	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	MAPRE1	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	CCNB2	PSMB7	CCNB1	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	GTSE1	PSMB9	FKBPL	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	PLK1	CDK1	HSP90AB1	PSMD8	PSMD9	HSP90AA1	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	TP53	
DEFECTIVE SLC2A1 CAUSES GLUT1 DEFICIENCY SYNDROME 1 (GLUT1DS1)%REACTOME DATABASE ID RELEASE 74%5619043	Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1)	SLC2A1	
BETAKLOTHO-MEDIATED LIGAND BINDING%REACTOME DATABASE ID RELEASE 74%1307965	betaKlotho-mediated ligand binding	FGF19	KLB	FGFR4	
TRIF(TICAM1)-MEDIATED TLR4 SIGNALING%REACTOME%R-HSA-937061.2	TRIF(TICAM1)-mediated TLR4 signaling	RPS6KA1	RIPK3	RIPK2	MAPK3	FOS	CREB1	UBE2D2	PTPN11	UBE2D1	TBK1	DUSP4	IRF3	TRAF3	TRAF6	IRF7	UBA52	UBE2V1	DUSP6	BIRC2	DUSP7	CUL1	RELA	BIRC3	UBE2N	UBB	TAB3	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	TANK	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	TICAM2	LY96	TICAM1	CASP8	RIPK1	CD14	FADD	TLR4	ATF1	APP	ATF2	UBE2D3	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	AGER	BTRC	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	IKBKE	CHUK	RPS6KA2	DUSP3	
GABA SYNTHESIS, RELEASE, REUPTAKE AND DEGRADATION%REACTOME%R-HSA-888590.1	GABA synthesis, release, reuptake and degradation	SLC32A1	SLC6A13	ABAT	SLC6A12	RIMS1	HSPA8	SLC6A11	RAB3A	SLC6A1	SYT1	CPLX1	STX1A	SNAP25	ALDH5A1	DNAJC5	VAMP2	GAD1	GAD2	
INTERLEUKIN-1 FAMILY SIGNALING%REACTOME%R-HSA-446652.7	Interleukin-1 family signaling	SQSTM1	RIPK2	IRAK3	IRAK4	TBK1	UBA52	PELI1	CUL1	UBB	PELI3	PELI2	NOD1	PTPN12	NOD2	UBC	MAPK8	RPS27A	S100B	TNIP2	SAA1	PTPN4	IL1RL1	IL33	MAP2K1	STAT3	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PTPN11	PSME1	PSME2	PSMD10	TRAF6	PSMB11	PSMD12	PSMD11	PSMD14	PTPN7	UBE2V1	PSMD13	PSMB10	PSMA7	RELA	PSMA8	PSMB6	UBE2N	PSMB7	TAB3	PSMB4	TAB2	PSMB5	TAB1	PSMB2	PSMB3	PSMB1	PSMF1	CTSG	SHFM1	IRAK2	PSMB8	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	NFKBIB	IL18	IL1A	IL1B	IL1RN	IL36A	IL18RAP	IL36B	IL1R2	IL36RN	IL36G	IL1F10	IL4	IL1R1	TOLLIP	PTPN20	PTPN23	IL18BP	IL13	IL1RAPL1	IL1RL2	PTPN18	MAP3K3	SMAD3	IL37	PTPN13	PTPN6	PTPN14	PTPN9	PTPN5	PTPN2	IL18R1	APP	CASP1	MAP2K4	RBX1	MAP3K8	SIGIRR	AGER	BTRC	IRAK1	S100A12	MAP2K6	SKP1	NFKB2	MYD88	FBXW11	HMGB1	NKIRAS1	NKIRAS2	ALOX5	
NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%9013508	NOTCH3 Intracellular Domain Regulates Transcription	NOTCH3	MAML3	MAMLD1	SNW1	STAT1	NOTCH1	MAML2	PLXND1	WWC1	MAML1	KAT2B	HEY1	DLGAP5	PTCRA	RBPJ	KAT2A	PBX1	HEYL	HEY2	FABP7	CREBBP	EP300	HES1	HES5	
DEFECTIVE SLC6A3 CAUSES PARKINSONISM-DYSTONIA INFANTILE (PKDYS)%REACTOME%R-HSA-5660724.1	Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)	SLC6A3	
PROLACTIN RECEPTOR SIGNALING%REACTOME DATABASE ID RELEASE 74%1170546	Prolactin receptor signaling	PRL	PRLR	RBX1	GHR	GH2	GH1	PTPN11	STAT5A	STAT5B	BTRC	SKP1	CUL1	JAK2	CSH1	
FORMATION OF RNA POL II ELONGATION COMPLEX%REACTOME%R-HSA-112382.2	Formation of RNA Pol II elongation complex	CTDP1	ELL	CCNT1	SUPT4H1	TCEB3	TCEB2	TCEB1	NELFA	NELFCD	TCEB3C	TCEB3CL	TCEB3B	NELFE	GTF2F1	SUPT16H	GTF2F2	SSRP1	SUPT5H	CDK9	TCEA1	TCEB3CL2	CCNK	NELFB	CDC73	CCNH	CTR9	WDR61	RTF1	POLR2A	POLR2B	POLR2C	NCBP1	POLR2D	LEO1	NCBP2	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	PAF1	POLR2K	POLR2L	GTF2H1	GTF2H2	CCNT2	AFF4	GTF2H3	MLLT1	GTF2H4	MLLT3	SUPT6H	GTF2H5	IWS1	EAF1	EAF2	CDK7	ERCC3	ERCC2	MNAT1	
GROWTH HORMONE RECEPTOR SIGNALING%REACTOME%R-HSA-982772.1	Growth hormone receptor signaling	PRL	PRLR	MAPK3	GHR	GH2	IRS1	GH1	MAPK1	STAT5A	STAT5B	SOCS1	IRS2	STAT1	SOCS3	STAT3	PTPN6	LYN	CISH	SOCS2	ADAM17	JAK2	PTPN1	CSH1	
FCERI MEDIATED CA+2 MOBILIZATION%REACTOME DATABASE ID RELEASE 74%2871809	FCERI mediated Ca+2 mobilization	NFATC1	IGKV2-28	IGKV1-12	IGKV3D-20	NFATC3	NFATC2	IGKV2D-28	IGKV4-1	IGHE	IGKV2D-30	IGKV3-11	PLCG1	LYN	IGKV5-2	SOS1	SYK	GRAP2	LCP2	PPP3CA	PPP3CB	AHCYL1	ITPR1	ITPR2	ITPR3	VAV1	PPP3R1	PLCG2	VAV3	ITK	VAV2	TXK	TEC	BTK	
DEFECTIVE UGT1A1 CAUSES HYPERBILIRUBINEMIA%REACTOME DATABASE ID RELEASE 74%5579002	Defective UGT1A1 causes hyperbilirubinemia	UGT1A1	
MRNA EDITING: C TO U CONVERSION%REACTOME%R-HSA-72200.4	mRNA Editing: C to U Conversion	APOBEC1	APOBEC3C	APOBEC2	APOBEC4	APOBEC3H	A1CF	APOBEC3A	APOBEC3B	
PREGNENOLONE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%196108	Pregnenolone biosynthesis	FDX1	FDXR	FDX1L	STARD3	STARD4	BZRAP1	STARD3NL	STARD6	STAR	CYP11A1	TSPO	AKR1B1	
DUAL INCISION IN TC-NER%REACTOME DATABASE ID RELEASE 74%6782135	Dual incision in TC-NER	POLK	UBA52	UBB	UBC	RPS27A	HMGN1	AQR	ZNF830	UVSSA	ERCC8	TCEA1	RPA1	RPA2	RPA3	PRPF19	ERCC4	ERCC1	XAB2	CCNH	XPA	CUL4A	DDB1	POLR2A	POLR2B	ERCC5	POLR2C	CUL4B	PPIE	POLR2D	POLR2E	RBX1	POLR2F	POLR2G	POLR2H	RFC5	POLR2I	RFC3	POLR2J	PCNA	POLR2K	RFC4	POLR2L	GTF2H1	RFC1	GTF2H2	GTF2H3	RFC2	GTF2H4	ISY1	POLE4	POLD3	GTF2H5	USP7	POLD4	CDK7	POLE2	POLD1	ERCC3	POLE3	POLD2	POLE	ERCC2	ERCC6	EP300	MNAT1	
CELLULAR RESPONSES TO EXTERNAL STIMULI%REACTOME%R-HSA-8953897.4	Cellular responses to external stimuli	DYNLL1	AJUBA	VCP	UBA52	DYNC1I2	DCTN2	DCTN3	UBB	UBC	EIF2S2	EIF2S1	RPS27A	NBN	EIF2S3	SUZ12	DYNC1H1	RPA1	RPA2	EPO	MRE11A	RAD50	RPA3	CEBPB	EHMT1	CXCL8	CEBPG	HSPA5	RPL4	RPL5	ASNS	RPL30	DDIT3	RPL3	RPL32	ATF3	RPL31	ATF4	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	IL6	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	SESN2	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	MAPKAPK5	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	GPX2	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	TXNRD1	RPL11	MAPKAPK2	RPL36A	RPS27L	HMGA1	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	HSPA8	MAPK14	MAPK11	RPL22L1	FAU	RPL26L1	HSPB8	CCAR2	HSBP1	SIRT1	DNAJC2	DNAJC7	FKBP4	CRYAB	RPS19BP1	HSPA4L	HSPA14	HSPA13	HDAC6	DNAJB1	BAG5	C11orf73	HSPH1	BAG2	DNAJB6	BAG3	BAG1	HSF1	HSPA1L	ST13	HSPA4	PTGES3	NCF1	HSPA6	NCF2	HSPA2	NCF4	HSPA12A	HSPA12B	CYBB	GPX1	RBX1	EP300	H1F0	HIST1H1D	HIST1H1E	HIST1H1A	HIST1H1B	HIST1H1C	PPP1R15A	MTF1	CAMK2B	CAMK2D	CDKN1A	CDKN1B	CAMK2G	MDM2	MDM4	EEF1A1	RB1	NUP107	NUP188	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	NUP214	NUP210	HIST1H2AJ	NUP93	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	NUP205	POM121	EHMT2	H2AFB1	HIST1H3J	ATF2	AAAS	UBE2D3	NUP160	MAP2K3	HIST1H3A	NUP85	RBBP4	MAP2K4	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	RBBP7	HIST1H3I	HIST1H3B	MAPKAPK3	HIST1H3C	HIST1H3D	HIST1H3E	NUP155	H3F3B	HIST1H4K	HIST1H4L	MAP2K7	MAP2K6	JUN	AR	H3F3A	NUP153	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	DYNC1LI1	DYNC1LI2	LMNB1	HIST2H2AC	FOS	H2AFJ	NUP62	UBE2D1	CDC23	NDC1	CDC26	CDC27	SEC13	NUP133	ANAPC7	H2AFZ	UBE2E1	H2AFX	H2AFV	CCNA2	CCNA1	HIST2H2BE	CCNE2	CCNE1	HIST4H4	NUP50	ANAPC4	ANAPC5	NUP54	EZH2	ANAPC1	HIST1H2BN	HIST1H2BM	ANAPC2	ANAPC15	HIST1H2BO	ANAPC16	RING1	HIST1H2BJ	ANAPC10	HIST1H2BI	MAPK9	ANAPC11	HIST1H2BL	MAPK8	MAPK7	FZR1	HIST1H2BK	MAPK10	HIST2H4A	HIST2H4B	MAPK1	UBE2C	NUP43	RAE1	RANBP2	UBE2S	CDC16	CDK2	HIST3H3	NUP35	NUPL2	NUP37	CAPZB	MT2A	MT1A	MT1M	MT1F	MT1G	MT1X	MT1H	MT1B	MT4	MT3	MT1E	CITED2	DYNLL2	ATP7A	DCTN6	DCTN5	DCTN1	DCTN4	HSP90AB1	CYCS	PSMD8	PSMD9	PSMD6	ATF5	PSMD7	ASF1A	PSMD4	SEH1L	PSMD5	NPRL2	DYNC1I1	PSMD2	NPRL3	PSMD3	HIF1A	PSMD1	PRDX3	WDR59	EIF2AK1	E2F1	EIF2AK4	PRDX6	PSMA5	NOX4	PSMA6	CAPZA3	NOX5	PSMA3	CSRP1	PSMA4	CAPZA1	MIOS	PSMA1	PSMA2	GSTP1	CAPZA2	PSME3	WDR24	UBE2D2	PSME4	UBN1	PSME1	EGLN1	PSME2	EGLN3	SP1	GATSL3	EGLN2	PSMD10	WTIP	PSMB11	ERO1L	ACTR10	PSMD12	SESN1	PSMD11	MAP3K5	PSMD14	ERF	PSMD13	TNIK	STIP1	PSMB10	C7orf60	PSMA7	HIF1AN	GPX3	RELA	PSMA8	GPX6	PSMB6	GPX5	PSMB7	GPX8	PSMB4	GPX7	PSMB5	IMPACT	PSMB2	GCN1L1	PSMB3	SH3BP4	PSMB1	E2F2	PSMF1	FNIP1	SHFM1	FNIP2	EPAS1	PSMB8	ATOX1	NFKB1	DNAJA1	PSMB9	DNAJA4	DNAJA2	PSMC5	AQP8	PSMC6	NUDT2	PSMC3	CHAC1	PSMC4	C12orf66	PSMC1	LIMD1	PSMC2	MINK1	ITFG2	DEPDC5	KPTN	HIRA	MAP4K4	ETS1	ETS2	NR3C2	TXN2	GATSL2	SZT2	HIGD1A	EP400	HMGA2	CABIN1	FLCN	CA9	KDM6B	VHL	HSPA9	SNCB	SOD3	SOD1	CCS	E2F3	BMI1	MTOR	MLST8	TRIB3	GSK3B	CAT	CAMK2A	CDK4	RNF2	TCIRG1	ATP6V1E1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	CREBBP	ATP6V1B2	ATP6V0D1	EED	ATP6V0D2	TP53	ARNT	ATP6V0C	ATP6V1B1	PHC2	ATP6V1A	PHC1	TNRC6C	ATP6V1H	MOV10	AGO3	PHC3	AGO4	ATP6V1G3	ATP6V0E2	AGO1	ATP6V1D	PRDX2	ATP6V1C1	PRDX1	ATP6V1C2	SOD2	ATP6V1F	TNRC6A	TNRC6B	IGFBP7	VENTX	TCEB2	CDKN2D	TCEB1	CDKN2B	CDKN2C	IFNB1	ATR	PGR	HIF3A	RPTOR	ATM	SLC38A9	FKBP5	RRAGA	RRAGC	RRAGB	RHEB	AKT1S1	RRAGD	LAMTOR2	CDK6	CDKN2A	LAMTOR1	LAMTOR4	LAMTOR3	LAMTOR5	BAG4	STAT3	GRB10	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	CUL2	TXN	VEGFA	TFDP1	IL1A	TFDP2	CBX8	CBX6	CBX4	CBX2	TINF2	TERF1	NR3C1	TERF2	POT1	TERF2IP	ACD	CYBA	KAT5	P4HB	YWHAE	ACTR1A	HSP90AA1	ID1	
SIGNAL ATTENUATION%REACTOME DATABASE ID RELEASE 74%74749	Signal attenuation	INSR	MAPK3	IRS1	MAPK1	SOS1	GRB10	INS	IRS2	SHC1	
CHK1 CHK2(CDS1) MEDIATED INACTIVATION OF CYCLIN B:CDK1 COMPLEX%REACTOME DATABASE ID RELEASE 74%75035	Chk1 Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	WEE1	YWHAQ	SFN	CHEK2	YWHAH	CHEK1	CDC25C	CDK1	YWHAG	YWHAB	CCNB1	YWHAZ	YWHAE	
PI-3K CASCADE:FGFR2%REACTOME%R-HSA-5654695.2	PI-3K cascade:FGFR2	PTPN11	FRS2	FGF20	FGF1	FGF23	FGF2	FGF22	FGF3	GAB1	FGF4	FGF16	FGF6	FGF7	FGF9	FGF18	PIK3R1	PIK3CA	FGF10	
POSTMITOTIC NUCLEAR PORE COMPLEX (NPC) REFORMATION%REACTOME%R-HSA-9615933.1	Postmitotic nuclear pore complex (NPC) reformation	AHCTF1	KPNB1	NUP62	NUP43	NUP93	NDC1	SEC13	NUP155	NUP133	NUP35	RANGAP1	NUP37	RAN	NUP107	SUMO1	RCC1	NUP188	UBE2I	NUP205	NUP54	TNPO1	POM121	NUP160	NUP85	
INTERCONVERSION OF 2-OXOGLUTARATE AND 2-HYDROXYGLUTARATE%REACTOME%R-HSA-880009.1	Interconversion of 2-oxoglutarate and 2-hydroxyglutarate	ADHFE1	D2HGDH	L2HGDH	
GDP-FUCOSE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%6787639	GDP-fucose biosynthesis	TSTA3	FUK	FPGT	FUOM	SLC35C1	GMDS	
CYCLIN A:CDK2-ASSOCIATED EVENTS AT S PHASE ENTRY%REACTOME%R-HSA-69656.3	Cyclin A:Cdk2-associated events at S phase entry	PSMA6	PSMA3	CDKN1A	PSMA4	CDKN1B	PSMA1	PSMA2	PSME3	PSME1	CDC25A	PSME2	PSMD10	SKP2	UBA52	PSMD12	PSMD11	CCNA2	PSMD14	LIN54	CCNA1	PSMD13	RBL2	CCNE2	LIN37	CCNE1	MAX	PSMB10	LIN9	CDC25B	PSMA7	E2F4	CUL1	E2F5	LIN52	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	FZR1	PSMB9	PSMC5	MYC	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CDK2	PTK6	RB1	TFDP1	TFDP2	CABLES1	WEE1	CKS1B	CCNH	AKT2	AKT3	RBBP4	AKT1	CCND1	CDK4	PSMD8	SKP1	CDK7	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	MNAT1	PSMD1	E2F1	PSMA5	
MYOGENESIS%REACTOME%R-HSA-525793.2	Myogenesis	MEF2B	MAPK12	SPAG9	ABL1	BNIP2	MYF6	CTNNB1	CDON	MYF5	TCF12	MEF2A	CDH15	CTNNA2	MEF2C	MYOG	MAPK14	NEO1	MAPK11	CTNNA1	MAP2K6	CDH4	CDH2	TCF4	TCF3	CDC42	NTN3	MEF2D	MYOD1	
TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS%REACTOME DATABASE ID RELEASE 74%168271	Transport of Ribonucleoproteins into the Host Nucleus	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	AAAS	NUP160	NUP85	TPR	KPNA1	NUP88	KPNB1	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	NUP107	NUP153	NUP188	
PROTON OLIGOPEPTIDE COTRANSPORTERS%REACTOME%R-HSA-427975.2	Proton oligopeptide cotransporters	SLC15A3	SLC15A4	SLC15A1	SLC15A2	
INTERFERON SIGNALING%REACTOME%R-HSA-913531.2	Interferon Signaling	NUP62	IRF3	NDC1	SEC13	NUP133	IRF7	UBA52	UBE2E1	NUP50	NUP54	UBB	UBC	RPS27A	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	JAK2	MT2A	EIF4A2	EIF4A1	PIN1	UBE2N	PRKCD	PSMB8	EIF4E	HLA-A	B2M	EIF4G1	SUMO1	HLA-DPA1	HLA-DQB2	HLA-DQB1	HLA-DQA2	HLA-DQA1	HLA-DRB5	HLA-DRB4	HLA-DPB1	HLA-DRA	HLA-DRB3	HLA-DRB1	SOCS3	IFNG	IFNGR1	IFNGR2	PTPN6	PIAS1	CAMK2A	NEDD4	IFNA13	IFNA14	IFNA16	IFNA17	IFNA10	ICAM1	JAK1	IFNA21	VCAM1	IFNA5	IFNA4	IFITM3	IFNA7	IFITM1	IFITM2	IFNA6	IFIT5	IFNA1	UBE2L6	IFI35	IFI30	IFIT1	IFNA2	IFIT3	IFIT2	HERC5	IFNA8	TRIM29	TRIM25	TRIM26	TRIM21	TRIM22	GBP6	GBP5	GBP7	RSAD2	IRF1	HLA-B	IRF2	HLA-C	HLA-F	HLA-G	HLA-E	TRIM17	PDE12	TRIM14	TRIM10	BST2	TRIM8	TRIM6	TRIM5	IFNB1	TRIM2	TRIM3	ARIH1	SP100	RNASEL	PTAFR	IFI6	FLNA	FLNB	MID1	UBA7	IP6K2	ISG20	XAF1	EIF4G3	EIF4G2	CIITA	EIF4E3	ADAR	OASL	TRIM68	TRIM62	DDX58	PPM1B	OAS1	IRF4	OAS2	OAS3	PTPN1	EIF4A3	IRF8	IRF5	USP41	IRF6	EIF4E2	IRF9	SAMHD1	PML	USP18	TRIM46	TRIM48	GBP2	GBP1	FCGR1B	GBP4	TRIM45	GBP3	MX2	MX1	TRIM35	STAT1	TRIM38	ABCE1	TRIM31	TRIM34	CAMK2B	CAMK2D	MAPK3	NCAM1	CAMK2G	PTPN11	PLCG1	KPNA7	KPNA4	KPNA5	KPNA2	KPNA3	KPNA1	KPNB1	EIF2AK2	ISG15	FCGR1A	NUP107	NUP188	CD44	NUP214	NUP210	NUP93	TYK2	IFNAR1	NUP205	POM121	AAAS	STAT2	NUP160	NUP85	TPR	NUP88	NUP155	SOCS1	NUP153	EGR1	
ACTIVATION OF BID AND TRANSLOCATION TO MITOCHONDRIA%REACTOME%R-HSA-75108.3	Activation of BID and translocation to mitochondria	GZMB	NMT1	BID	CASP8	
TRANSCRIPTIONAL REGULATION BY RUNX1%REACTOME%R-HSA-8878171.3	Transcriptional regulation by RUNX1	HIST2H2AC	H2AFJ	UBA52	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	CTLA4	UBB	HIST1H2BN	HIST1H2BM	ACTL6B	HIST1H2BO	RING1	UBC	HIST1H2BJ	HIST1H2BI	ACTL6A	HIST1H2BL	RPS27A	HIST1H2BK	HIST2H4A	HIST2H4B	SERPINB13	KMT2D	KMT2A	KMT2C	TP73	FOXP3	HIPK2	KMT2E	KMT2B	PSMD8	PSMD9	PSMD6	BLK	PSMD7	ELF1	PSMD4	ELF2	PSMD5	PAX5	PSMD2	PSMD3	PSMD1	AXIN1	PSMA5	PSMA6	PSMA3	SOCS4	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PRKCQ	PSMD14	PSMD13	PSMB10	YAF2	PSMA7	PSMA8	PSMB6	TNFRSF18	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	SMARCA4	SMARCB1	LGALS3	SMARCC1	SMARCC2	ESR1	YAP1	CSNK2A1	SRC	CSNK2A2	SMARCA2	BMI1	SOCS3	CSNK2B	IFNG	CCND3	PBRM1	ARID2	AUTS2	DPY30	CCND1	RNF2	TCF3	LDB1	MYB	CREBBP	EP300	ZFPM1	PHC2	PHC1	GATA3	GATA2	GATA1	SETD1B	ITCH	SETD1A	TNRC6C	MOV10	ABL1	AGO3	NFE2	PHC3	AGO4	AGO1	AGO2	RSPO3	TNRC6A	TNRC6B	GPAM	CSF2	ITGA2B	SIN3A	PCGF5	RYBP	HDAC1	NFATC2	ASH2L	IL2	IL3	MYL9	TCF12	TAL1	PML	CCND2	CDK6	SIN3B	CR1	CBFB	PTPN11	IL2RA	SMARCD1	PRMT1	SMARCD2	CTSV	SMARCE1	CTSL	CTSK	WDR5	OCLN	PRMT6	TJP1	LMO1	LMO2	LIFR	KCTD6	HIST1H2AE	CBX8	HIST1H2AD	SMARCD3	CBX6	HIST3H2BB	CBX4	HIST1H2AC	CBX2	HIST1H2AB	PRKCB	NR4A3	HIST1H2AJ	RBBP5	ARID1A	ARID1B	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	THBS1	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	CCNH	H2AFB1	HIST1H3J	HIST1H3A	RUNX1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	GP1BA	KAT2B	H3F3A	CDK7	CLDN5	H2BFS	HIST1H4A	SPI1	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	MNAT1	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	PF4	HIST2H2AA4	
SIGNALING BY FGFR1 IN DISEASE%REACTOME DATABASE ID RELEASE 74%5655302	Signaling by FGFR1 in disease	FGF20	FGF23	GAB2	GAB1	NRAS	PLCG1	SOS1	HRAS	PIK3R1	PIK3CA	ERLIN2	ZMYM2	FGFR1OP2	TRIM24	MYO18A	STAT5A	LRRFIP1	STAT5B	FRS2	BCR	BAG4	FGF1	CUX1	CPSF6	FGF2	STAT1	STAT3	FGF4	FGFR1OP	FGF6	FGFR1	FGF9	
TRANSFER OF LPS FROM LBP CARRIER TO CD14%REACTOME%R-HSA-166020.2	Transfer of LPS from LBP carrier to CD14	CD14	LBP	
RNA POLYMERASE III TRANSCRIPTION INITIATION%REACTOME%R-HSA-76046.2	RNA Polymerase III Transcription Initiation	GTF3C1	GTF3C2	GTF3C3	CRCP	GTF3C4	GTF3C5	GTF3C6	SNAPC5	SNAPC1	SNAPC2	SNAPC3	SNAPC4	ZNF143	POU2F1	POLR2E	BRF2	POLR2F	TBP	BRF1	POLR2H	POLR3GL	GTF3A	POLR3A	POLR3B	POLR2K	POLR2L	POLR3C	POLR3D	POLR3E	POLR1C	POLR3F	POLR3G	POLR3H	BDP1	POLR3K	
RHO GTPASE CYCLE%REACTOME%R-HSA-194840.4	Rho GTPase cycle	ARHGEF26	ABR	NGEF	ECT2	ARHGEF33	ARHGEF35	ARHGEF37	ARHGEF39	ARHGEF38	NET1	ARHGEF10L	RACGAP1	AKAP13	MCF2L	ARHGEF10	PLEKHG2	TRIO	ARHGEF15	PLEKHG5	ARHGEF17	ARHGEF16	ARHGEF19	ARHGEF18	ARHGEF9	ARHGEF3	ARHGEF4	RAC1	ARHGEF1	ARHGAP10	ARHGEF2	ARHGEF5	ARHGEF6	ARHGAP39	VAV1	ARHGAP35	FGD1	FGD2	GNA13	FGD3	FGD4	MCF2	CDC42	GDI1	GDI2	ARHGEF11	ARHGEF12	RHOC	RHOA	RHOQ	RHOB	TRIP10	OCRL	RASGRF2	BCR	A2M	SRGAP3	SRGAP1	SOS1	KALRN	FAM13B	FAM13A	ARHGDIG	VAV3	SOS2	ARHGAP36	SYDE2	VAV2	ARHGAP44	SYDE1	ARHGAP42	OPHN1	ARHGAP40	ARHGEF7	ARHGDIB	RALBP1	STARD8	HMHA1	DEPDC1B	ARHGAP19	ARHGAP18	ARHGAP17	ARHGAP15	MYO9B	RHOBTB1	ARHGAP12	RHOBTB2	ARHGAP22	INPP5B	ARHGAP21	ARHGAP20	RHOT2	RHOT1	STARD13	ARHGAP29	ARHGAP28	ARHGAP27	ARHGAP26	ARHGAP25	PIK3R2	ARHGAP24	ARHGAP23	RAC2	ARHGAP33	ARHGAP32	ARHGAP31	ARHGAP30	ARHGAP11A	ARHGAP9	TIAM1	ARHGAP11B	ARHGAP8	ARHGAP1	ARHGAP5	ARHGAP6	ARHGAP4	TAGAP	RAC3	RHOG	ARAP2	RHOH	ARAP3	ARAP1	RHOF	GMIP	RHOD	DEPDC7	RHOJ	RHOU	RHOV	PREX1	CHN2	ARHGDIA	CHN1	ARHGEF40	MYO9A	ITSN1	DLC1	TIAM2	OBSCN	
DEFECTIVE PAPSS2 CAUSES SEMD-PA%REACTOME%R-HSA-3560796.1	Defective PAPSS2 causes SEMD-PA	PAPSS2	
ASTROCYTIC GLUTAMATE-GLUTAMINE UPTAKE AND METABOLISM%REACTOME DATABASE ID RELEASE 74%210455	Astrocytic Glutamate-Glutamine Uptake And Metabolism	GLUL	SLC1A3	SLC38A1	SLC1A2	
NEF-MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS%REACTOME%R-HSA-164938.1	Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	AP2A2	CD28	CD4	AP1G1	PACS1	AP1B1	AP2M1	AP1S2	AP1S1	ARF1	ATP6V1H	AP1S3	HLA-A	B2M	AP2B1	AP1M2	AP1M1	CD8B	AP2A1	LCK	AP2S1	
TRAF6 MEDIATED IRF7 ACTIVATION%REACTOME DATABASE ID RELEASE 74%933541	TRAF6 mediated IRF7 activation	IFIH1	RNF135	IFNA10	TRAF2	MAVS	SIKE1	TBK1	IRF3	TRAF6	IRF7	IFNA21	DDX58	IFNA5	IFNA4	TANK	IFNA7	IFNA6	IFNA1	IFNA2	IFNA8	TRIM25	IFNA13	CREBBP	EP300	IFNA14	IFNA16	IFNA17	IKBKE	IFNB1	
EPHA-MEDIATED GROWTH CONE COLLAPSE%REACTOME%R-HSA-3928663.3	EPHA-mediated growth cone collapse	FYN	ROCK1	ROCK2	NGEF	RHOA	YES1	MYL12B	MYL6	MYH9	MYH14	MYH11	LYN	MYH10	MYL9	
HDR THROUGH HOMOLOGOUS RECOMBINATION (HRR)%REACTOME%R-HSA-5685942.1	HDR through Homologous Recombination (HRR)	POLK	CHEK1	UBA52	MUS81	EME1	EME2	POLH	GEN1	SLX1B	UBB	SPIDR	SLX1A	RTEL1	RAD51AP1	UBC	SLX4	BRCA1	XRCC2	BRCA2	XRCC3	NBN	RPS27A	PALB2	TOP3A	BLM	RBBP8	RPA1	RPA2	MRE11A	RAD51B	RAD50	RAD51C	RAD51	RPA3	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	RAD17	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	KAT5	ATM	RAD51D	RFC5	RFC3	PCNA	RFC4	RFC1	RFC2	POLE4	POLD3	POLD4	POLE2	POLD1	POLE3	POLD2	POLE	
LXRS REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX%REACTOME%R-HSA-9029569.1	LXRs regulate gene expression linked to cholesterol transport and efflux	RXRA	APOE	ABCG8	ABCA1	ABCG5	TBL1XR1	NR1H2	APOC4	TNRC6C	ABCG1	MOV10	NR1H3	AGO3	AGO4	APOC2	AGO1	AGO2	APOC1	RXRB	TNRC6A	TNRC6B	NCOR2	GPS2	NCOR1	TBL1X	KDM3A	KDM1B	KDM4A	ARL4C	EEPD1	KDM1A	NCOA1	CETP	EP300	APOD	HDAC3	
DEFECTIVE OGG1 SUBSTRATE PROCESSING%REACTOME DATABASE ID RELEASE 74%9656256	Defective OGG1 Substrate Processing	OGG1	
GABA B RECEPTOR ACTIVATION%REACTOME%R-HSA-977444.2	GABA B receptor activation	ADCY2	KCNJ5	ADCY1	KCNJ6	ADCY8	GABBR1	ADCY7	KCNJ10	ADCY6	KCNJ12	ADCY5	KCNJ9	KCNJ15	GNG12	KCNJ16	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNAL	GNB5	GNAT3	GNGT1	GNGT2	ADCY9	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	GNAI3	KCNJ2	ADCY4	KCNJ3	GNAI1	KCNJ4	ADCY3	GNAI2	GABBR2	
G-PROTEIN ACTIVATION%REACTOME%R-HSA-202040.1	G-protein activation	GNG12	OPRM1	GNG11	GNG13	GNAO1	GNB2	GNAZ	GNAT1	GNB1	GNB4	GNB3	GNB5	GNAT3	GNGT1	GNGT2	POMC	GNAT2	PDYN	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	GNAI3	GNAI1	GNAI2	
DEFECTIVE C1GALT1C1 CAUSES TN POLYAGGLUTINATION SYNDROME (TNPS)%REACTOME DATABASE ID RELEASE 74%5083632	Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)	MUC3A	MUC5AC	MUC1	MUC7	MUC12	MUC13	MUC15	MUC20	MUC4	MUC21	C1GALT1	MUC6	C1GALT1C1	MUCL1	MUC17	MUC5B	
KILLING MECHANISMS%REACTOME%R-HSA-9664420.1	Killing mechanisms	JUN	FZD7	DVL1	DVL2	DVL3	WNT5A	NOXA1	NOX1	CYBA	RAC1	NOXO1	MAPK8	
INTRACELLULAR SIGNALING BY SECOND MESSENGERS%REACTOME DATABASE ID RELEASE 74%9006925	Intracellular signaling by second messengers	IRAK4	UBA52	PIP5K1C	EZH2	UBB	PRKAR2B	RING1	UBC	RPS27A	PPP2CA	SUZ12	PPP2CB	MAPK1	PIK3CD	IRS2	PIK3CB	VAV1	PPARG	IER3	PIP5K1A	PIP5K1B	SNAI1	SNAI2	STRN	MECOM	PHLPP2	PHLPP1	ATN1	MAF1	TRAT1	PIK3AP1	PIP4K2A	PIP4K2B	PIP4K2C	RPS6KB2	FOXO6	USP7	FOXO4	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	GSK3A	PSMD5	PSMD2	PSMD3	PSMD1	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PTEN	PSMD10	TRAF6	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PRKCD	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	ESR1	CSNK2A1	IRS1	SRC	CSNK2A2	CD19	BMI1	CSNK2B	PRR5	CD86	PDPK1	MAPKAP1	CD80	PIK3R3	PIK3R2	PIK3R1	RAC2	MTOR	PIK3CA	LCK	AKT2	PRKACG	AKT3	PRKACB	MLST8	CD28	THEM4	AKT1	TRIB3	ADCY9	PRKAR1B	FYN	RICTOR	PRKAR1A	FRS2	PRKAR2A	GSK3B	CAMK2A	EREG	RNF2	BTC	ITPR1	PREX2	ITPR2	TRIM27	ITPR3	PDGFB	USP13	TGFA	WWP2	RNF146	NEDD4	KDM1A	MKRN1	FRK	OTUD3	ADCY4	EED	TP53	ADCY3	ADCY2	ADCY1	PHC2	AREG	ADCY8	ADCY7	ADCY6	CREB1	PHC1	ADCY5	FOXO1	TNRC6C	MOV10	AGO3	PHC3	AGO4	AGO1	PRKCG	AGO2	PDE1C	PDE1B	PDE1A	ADRBK1	TNRC6A	TNRC6B	CAMKK1	CAMKK2	KIT	HBEGF	NBEA	INSR	CAMK4	EPGN	FOXO3	KLB	TNKS2	TNKS	RAC1	FGF1	FGF2	FGF3	FGF4	FGF6	FGF7	FGF9	HDAC2	HDAC1	IL1RL1	XIAP	IL33	PDGFRB	PDGFRA	CASP9	HGF	FGF20	FGF23	FGF22	RPTOR	FGF16	ERBB2	SLC38A9	FGF19	STUB1	TSC2	FGF18	FGFR4	RRAGA	FGF10	RRAGC	BAD	RRAGB	RHEB	PML	AKT1S1	RRAGD	LAMTOR2	LAMTOR1	LAMTOR4	LAMTOR3	LAMTOR5	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	NRG1	PPP2R5C	NRG2	SALL4	NRG3	NRG4	MET	CAMK2B	CAMK2D	MAPK3	PRKCE	CDKN1A	CDKN1B	CAMK2G	PTPN11	MDM2	HDAC5	EGF	GAB1	HDAC7	EGFR	PLCG1	KPNA2	AHCYL1	PRKX	PPP2R1B	CBX8	CBX6	HDAC3	CBX4	CBX2	ESR2	NR4A1	PRKCA	NR2E1	INS	CHD4	CHD3	ATF2	REST	MTA1	RBBP4	RBBP7	MTA2	PPP2R1A	MTA3	RHOG	MBD3	PRKACA	IRAK1	GATAD2B	GATAD2A	JUN	EGR1	MYD88	
EUKARYOTIC TRANSLATION TERMINATION%REACTOME DATABASE ID RELEASE 74%72764	Eukaryotic Translation Termination	RPL41	N6AMT1	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	UBA52	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	GSPT2	RPS27A	RPL13	RPL15	GSPT1	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	APEH	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	TRMT112	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	ETF1	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	
AXONAL GROWTH INHIBITION (RHOA ACTIVATION)%REACTOME DATABASE ID RELEASE 74%193634	Axonal growth inhibition (RHOA activation)	RTN4	ARHGDIA	LINGO1	MCF2	NGFR	MAG	OMG	RHOA	
DOWNREGULATION OF ERBB2:ERBB3 SIGNALING%REACTOME%R-HSA-1358803.1	Downregulation of ERBB2:ERBB3 signaling	NRG1	RPS27A	ERBB2	AKT1	NRG2	UBB	USP8	UBC	UBA52	RNF41	AKT2	AKT3	
RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2+%REACTOME DATABASE ID RELEASE 74%76005	Response to elevated platelet cytosolic Ca2+	TUBA4A	PRKCG	TF	SPARC	STXBP3	ABCC4	ITGA2B	APOA1	RAB27B	HGF	VCL	LEFTY2	ALDOA	FLNA	PPIA	HSPA5	CD9	CD109	ITGB3	CFL1	BRPF3	A2M	EGF	FAM49B	ISLR	LAMP2	HABP4	FAM3C	CHID1	APLP2	ACTN1	SERPINF2	ACTN4	GTPBP2	SYTL4	SEPP1	TIMP1	TMX3	TAGLN2	FIGF	SCG3	NHLRC2	TEX264	VEGFB	STXBP2	ENDOD1	VEGFC	A1BG	CYB5R1	VEGFA	APOH	PSAP	VTI1B	TGFB2	SERPINA1	TGFB3	RARRES2	IGF2	IGF1	PPBP	MANF	SELP	SCCPDH	CALU	MAGED2	CAP1	HRG	FERMT3	LGALS3BP	CLU	SERPINA3	ORM1	PLG	ECM1	WDR1	APOOL	PLEK	OLA1	SOD1	CTSW	ORM2	SERPINA4	PRKCB	TMSB4X	PHACTR2	TIMP3	PRKCA	QSOX1	CFD	SRGN	STX4	AHSG	ANXA5	MMRN1	TOR4A	CD63	ITIH4	ITIH3	THBS1	TTN	CLEC3B	ALB	CDC37L1	SPP2	TGFB1	LY6G6F	PCDH7	LHFPL2	PCYOX1L	FN1	GAS6	APP	PROS1	F13A1	KNG1	PFN1	FGB	FGA	ACTN2	VWF	TLN1	FGG	SERPINE1	PDGFB	F5	F8	SERPING1	CD36	PF4	
GLUCURONIDATION%REACTOME%R-HSA-156588.3	Glucuronidation	SLC35D1	UGT2B10	UGT1A10	UGT1A4	UGT2B11	UGT2B15	UGT2B17	UGT2B28	UGDH	ABHD10	UGP2	UGT1A5	UGT2A3	UGT3A2	UGT2B4	UGT1A9	UGT3A1	UGT1A3	UGT1A8	UGT2B7	UGT1A7	UGT1A6	UGT1A1	
VASOPRESSIN-LIKE RECEPTORS%REACTOME%R-HSA-388479.2	Vasopressin-like receptors	OXTR	AVPR1B	OXT	AVPR1A	AVP	AVPR2	
TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES%REACTOME DATABASE ID RELEASE 74%5633008	TP53 Regulates Transcription of Cell Death Genes	TNFRSF10C	TNFRSF10B	PERP	TNFRSF10A	TP53I3	BCL6	TP53AIP1	PPP1R13B	FAS	BAX	TRIAP1	TP63	PIDD1	CASP6	RABGGTB	TP53BP2	RABGGTA	TNFRSF10D	BIRC5	PRELID1	TMEM219	CRADD	ATM	NLRC4	TP53INP1	TP73	CHM	BBC3	CASP10	CASP1	CASP2	AIFM2	BID	STEAP3	BNIP3L	IGFBP3	APAF1	NDRG1	CREBBP	PMAIP1	BCL2L14	ZNF420	SLMO1	TP53	
DRUG-MEDIATED INHIBITION OF ERBB2 SIGNALING%REACTOME DATABASE ID RELEASE 74%9652282	Drug-mediated inhibition of ERBB2 signaling	ERBB2	HSP90AA1	CDC37	ERBB2IP	
DEFECTIVE MMAB CAUSES METHYLMALONIC ACIDURIA TYPE CBLB%REACTOME DATABASE ID RELEASE 74%3359471	Defective MMAB causes methylmalonic aciduria type cblB	MMAB	
HHAT G278V ABROGATES PALMITOYLATION OF HH-NP%REACTOME DATABASE ID RELEASE 74%5658034	HHAT G278V abrogates palmitoylation of Hh-Np	IHH	HHAT	SHH	DHH	
NORC NEGATIVELY REGULATES RRNA EXPRESSION%REACTOME%R-HSA-427413.2	NoRC negatively regulates rRNA expression	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	SAP130	H2AFV	SAP30BP	DNMT1	HIST2H2BE	BAZ2A	SMARCA5	HIST4H4	DNMT3B	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	SIN3A	HDAC2	HDAC1	MBD2	POLR2E	POLR2F	POLR2H	POLR2K	POLR2L	SIN3B	TBP	POLR1C	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	ARID4B	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	SAP30	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	SAP30L	CCNH	SAP18	H2AFB1	SUDS3	HIST1H3J	TTF1	TAF1D	ZNRD1	HIST1H3A	TAF1B	HIST1H3F	TAF1C	HIST1H3G	TWISTNB	TAF1A	HIST1H3H	UBTF	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	CD3EAP	HIST1H3E	GTF2H1	GTF2H2	H3F3B	GTF2H3	HIST1H4K	GTF2H4	HIST1H4L	GTF2H5	H3F3A	CDK7	H2BFS	ERCC3	HIST1H4A	POLR1A	HIST1H4B	POLR1B	HIST1H4H	ERCC2	HIST1H4I	POLR1E	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
INTESTINAL HEXOSE ABSORPTION%REACTOME%R-HSA-8981373.1	Intestinal hexose absorption	SLC2A2	RSC1A1	SLC5A1	SLC2A5	
TRANSCRIPTIONAL ACTIVATION OF P53 RESPONSIVE GENES%REACTOME%R-HSA-69560.2	Transcriptional activation of p53 responsive genes	CDKN1A	ZNF385A	PCBP4	TP53	
DEFECTIVE ACY1 CAUSES ENCEPHALOPATHY%REACTOME DATABASE ID RELEASE 74%5579007	Defective ACY1 causes encephalopathy	ACY1	
MATURATION OF PROTEIN 3A%REACTOME%R-HSA-9683673.2	Maturation of protein 3a	ST3GAL4	ST6GALNAC3	ST6GALNAC4	GALNT1	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	ST6GALNAC2	
ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR (ANDROGEN RECEPTOR) REGULATED GENES KLK2 AND KLK3%REACTOME DATABASE ID RELEASE 74%5625886	Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	KLK3	HIST1H2BL	KDM4C	PKN1	HIST1H2BK	HIST2H4A	HIST2H4B	NCOA2	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	AR	H3F3A	KDM1A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	KLK2	
FORMATION OF INCISION COMPLEX IN GG-NER%REACTOME%R-HSA-5696395.1	Formation of Incision Complex in GG-NER	UBA52	PIAS1	SUMO3	SUMO2	UBE2V2	CCNH	XPA	UBE2N	UBB	PIAS3	PARP2	CHD1L	CUL4A	DDB1	UBC	ERCC5	CUL4B	CETN2	RPS27A	DDB2	RBX1	XPC	USP45	RAD23A	RAD23B	RPA1	RPA2	GTF2H1	GTF2H2	GTF2H3	PARP1	GTF2H4	GTF2H5	RPA3	CDK7	SUMO1	ERCC3	RNF111	UBE2I	ERCC2	MNAT1	ERCC4	ERCC1	
KANDUTSCH-RUSSELL PATHWAY%REACTOME DATABASE ID RELEASE 74%6807062	Kandutsch-Russell pathway	EBP	SC5D	DHCR24	DHCR7	
REGULATION BY C-FLIP%REACTOME%R-HSA-3371378.1	Regulation by c-FLIP	TNFRSF10B	TRAF2	TNFRSF10A	FASLG	CASP8	TNFSF10	FAS	RIPK1	FADD	TRADD	
ALPHA-LINOLENIC ACID (ALA) METABOLISM%REACTOME DATABASE ID RELEASE 74%2046106	alpha-linolenic acid (ALA) metabolism	ACOT8	ACSL1	HSD17B4	ELOVL1	FADS2	ACAA1	SCP2	ABCD1	ELOVL5	ELOVL2	ELOVL3	FADS1	
G-PROTEIN BETA:GAMMA SIGNALLING%REACTOME DATABASE ID RELEASE 74%397795	G-protein beta:gamma signalling	GNG12	GNG11	GNG13	RHOA	GNB2	GNB1	GNB4	GNB3	PDPK1	GNB5	AKT2	AKT3	GNGT1	AKT1	GNGT2	PLCB3	PLCB1	PLCB2	PIK3CG	ARHGEF6	PIK3R5	GNG3	GNG10	GNG2	GNG5	GNG4	CDC42	GNG7	GNG8	PIK3R6	PAK1	BTK	
MANIPULATION OF HOST ENERGY METABOLISM%REACTOME%R-HSA-9636667.2	Manipulation of host energy metabolism	ENO1	PGK1	
NUCLEOBASE CATABOLISM%REACTOME%R-HSA-8956319.1	Nucleobase catabolism	NT5E	GDA	DPYS	NUDT5	NT5C2	DNPH1	TYMP	NT5C	UPP2	PNP	NT5M	UPP1	ENTPD1	NUDT16	GPX1	ENTPD5	SAMHD1	NUDT15	XDH	ENTPD2	ENTPD3	AGXT2	ENTPD4	ENTPD6	ENTPD7	ENTPD8	UPB1	NT5C1A	DPYD	NT5C1B	ADPRM	ITPA	
FGFR3 MUTANT RECEPTOR ACTIVATION%REACTOME%R-HSA-2033514.1	FGFR3 mutant receptor activation	FGFR3	FGF4	FGF16	FGF9	FGF18	FGF20	FGF1	FGF23	FGF2	
ION INFLUX EFFLUX AT HOST-PATHOGEN INTERFACE%REACTOME DATABASE ID RELEASE 74%6803544	Ion influx efflux at host-pathogen interface	PDZD11	ATP7A	SLC11A1	ATOX1	
TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR%REACTOME DATABASE ID RELEASE 74%1679131	Trafficking and processing of endosomal TLR	CTSB	CNPY3	HSP90B1	TLR8	TLR7	CTSV	CTSS	TLR3	LGMN	UNC93B1	CTSL	CTSK	TLR9	
TNF SIGNALING%REACTOME DATABASE ID RELEASE 74%75893	TNF signaling	NSMAF	TRAF2	CASP8	SHARPIN	RIPK1	FADD	UBA52	GNB2L1	CYLD	TNFAIP3	BIRC2	OTUD7B	BIRC3	SMPD3	SMPD2	UBB	TAB3	TAB2	TAB1	UBC	RPS27A	TRAF1	TNFRSF1A	TAX1BP1	BAG4	RNF31	TNF	SPPL2B	SPPL2A	IKBKB	ADAM17	USP21	XIAP	USP4	USP2	OTULIN	CLIP3	IKBKG	MAP3K7	CHUK	TRADD	RBCK1	
CELL REDOX HOMEOSTASIS%REACTOME DATABASE ID RELEASE 74%1222541	Cell redox homeostasis	
SARS-COV-2 GENOME REPLICATION AND TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%9694682	SARS-CoV-2 Genome Replication and Transcription	RB1	ZCRB1	GSK3A	DDX5	GSK3B	VHL	
TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION%REACTOME%R-HSA-975138.2	TRAF6 mediated induction of NFkB and MAP kinases upon TLR7 8 or 9 activation	RPS6KA1	RIPK2	MAPK3	IRAK4	FOS	CREB1	DUSP4	TRAF6	PELI1	UBA52	TLR7	UBE2V1	DUSP6	DUSP7	CUL1	RELA	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	TLR9	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	TICAM2	LY96	TICAM1	CD14	TLR4	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	AGER	BTRC	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
UCH PROTEINASES%REACTOME%R-HSA-5689603.2	UCH proteinases	HIST2H2AC	NEDD8	UBA52	UBB	UBC	OGT	ACTL6A	RPS27A	HIST2H2AB	HIST1H2AG	KDM1B	HIST1H2AA	HIST1H2AM	HIST1H2AL	HIST1H2AI	HIST1H2AH	HIST1H2AK	HIST3H2A	BARD1	YY1	USP15	UCHL5	SMAD7	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	RUVBL1	PSME1	NFRKB	PSME2	HCFC1	PSMD10	INO80C	INO80B	PSMB11	PSMD12	INO80E	PSMD11	INO80D	PSMD14	INO80	PSMD13	BAP1	UCHL1	SENP8	PSMB10	ACTR5	ACTR8	PSMA7	UCHL3	FOXK2	PSMA8	FOXK1	PSMB6	PSMB7	TFPT	PSMB4	MBD5	PSMB5	MBD6	PSMB2	MCRS1	PSMB3	ADRM1	PSMB1	ASXL1	PSMF1	ASXL2	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	ACTB	HIST1H2AE	HIST1H2AD	HIST1H2AC	HIST1H2AB	HIST1H2AJ	TGFB1	TGFBR1	TGFBR2	HIST2H2AA3	HIST2H2AA4	
IRS-MEDIATED SIGNALLING%REACTOME%R-HSA-112399.3	IRS-mediated signalling	IRS1	PTPN11	FGF20	FGF23	GAB2	FGF22	GAB1	FGF16	NRAS	PDPK1	SOS1	HRAS	FGF19	PIK3R2	FGF18	PIK3R1	FGFR4	PIK3CA	AKT2	TLR9	FGF10	FLT3	PDE3B	THEM4	TRIB3	KLB	FLT3LG	FRS2	IRS2	FGF1	PIK3CB	FGF2	FGF3	PIK3R4	FGF4	FGF6	FGF7	FGF9	PIK3C3	
DEFECTIVE CP CAUSES ACERULOPLASMINEMIA (ACERULOP)%REACTOME%R-HSA-5619060.1	Defective CP causes aceruloplasminemia (ACERULOP)	CP	SLC40A1	
REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO-FACTORS%REACTOME DATABASE ID RELEASE 74%6804759	Regulation of TP53 Activity through Association with Co-factors	AKT1	PHF20	PPP1R13B	POU4F1	ZNF385A	POU4F2	TP63	PPP1R13L	TP53BP2	BANP	TP73	AKT2	AKT3	TP53	
DEFECTIVE B4GALT1 CAUSES B4GALT1-CDG (CDG-2D)%REACTOME%R-HSA-4793953.1	Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	B4GALT1	
GLYCOSAMINOGLYCAN METABOLISM%REACTOME DATABASE ID RELEASE 74%1630316	Glycosaminoglycan metabolism	CHST7	B3GNT4	CHPF2	B3GNT3	B3GNT2	CHST1	B4GALT7	GLB1	B4GALT6	CHST5	B4GALT4	B4GALT5	CHST2	CHST3	CHSY1	HAS1	SLC26A2	HAS3	SLC26A1	HAS2	CHSY3	B3GAT2	B3GAT1	HS3ST5	HS3ST6	LYVE1	SLC9A1	HS3ST4	HS3ST1	HS3ST2	IDUA	HEXB	NCAN	HEXA	BGN	VCAN	HYAL1	HYAL3	ABCC5	IDS	SDC4	CSPG5	CSPG4	B3GAT3	SDC3	ARSB	GPC3	SDC1	GPC2	GPC5	GPC4	GPC6	B4GALT1	STAB2	AGRN	PAPSS1	HSPG2	BCAN	ST3GAL4	ST3GAL1	ST3GAL2	ST3GAL3	SDC2	CHST6	DCN	GLB1L	LUM	OGN	OMD	CD44	PRELP	KERA	FMOD	GNS	SLC35B3	SLC35B2	SLC35D2	GPC1	CHPF	HPSE2	XYLT2	XYLT1	HS6ST1	HS6ST2	HS6ST3	NDST2	NDST1	NAGLU	NDST4	NDST3	CHP1	CSGALNACT1	GLCE	CSGALNACT2	CEMIP	HS3ST3A1	B4GAT1	HMMR	CHST11	CHST12	DSEL	CHST15	CHST13	CHST14	B3GALT6	EXT1	ST3GAL6	EXT2	UST	HPSE	B4GALT2	B4GALT3	PAPSS2	SGSH	HS2ST1	HYAL2	DSE	B3GNT7	GUSB	HS3ST3B1	
DEFECTIVE BASE EXCISION REPAIR ASSOCIATED WITH NEIL3%REACTOME DATABASE ID RELEASE 74%9629232	Defective Base Excision Repair Associated with NEIL3	NEIL3	
TRANSCRIPTION OF SARS-COV-2 SGRNAS%REACTOME DATABASE ID RELEASE 74%9694786	Transcription of SARS-CoV-2 sgRNAs	
SYNTHESIS, SECRETION, AND INACTIVATION OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP)%REACTOME%R-HSA-400511.2	Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	GPR119	DPP4	SPCS3	GATA4	GIP	SPCS2	ISL1	SPCS1	FFAR1	SEC11A	SEC11C	PAX6	PCSK1	
TRANS-GOLGI NETWORK VESICLE BUDDING%REACTOME%R-HSA-199992.3	trans-Golgi Network Vesicle Budding	SH3D19	DNAJC6	FTL	HGS	DNM2	DNASE2	CHMP2A	CLVS2	CLVS1	DTNBP1	HIP1R	TPD52L1	TGOLN2	NECAP1	BLOC1S4	BLOC1S6	BLOC1S1	BLOC1S3	SNAPIN	M6PR	PIK3C2A	IGF2R	AP1G1	AP1B1	AP1S2	AP1S1	ARF1	AP1S3	SNX2	HSPA8	CLTC	CLTA	SNX9	AP1M2	SNX5	AP1M1	TBC1D8B	CLINT1	AP3S1	PUM1	VAMP8	GNS	CTSZ	VAMP7	AP4E1	VAMP2	STX4	GAK	TPD52	AP3B1	CLTB	SORT1	GOLGB1	YIPF6	SH3GL2	RAB5C	AP4S1	TXNDC5	APP	NAPA	OCRL	ARRB1	TFRC	FTH1	CPD	AP4B1	ACBD3	PICALM	SNAP23	AP4M1	GBF1	AP1G2	
DEFECTIVE HEXA CAUSES GM2G1%REACTOME%R-HSA-3656234.1	Defective HEXA causes GM2G1	HEXA	
LTC4-CYSLTR MEDIATED IL4 PRODUCTION%REACTOME%R-HSA-9664535.1	LTC4-CYSLTR mediated IL4 production	GGT5	CYSLTR1	GGT1	CYSLTR2	DPEP2	DPEP1	DPEP3	
LXRS REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS%REACTOME%R-HSA-9632974.1	LXRs regulate gene expression linked to gluconeogenesis	RXRA	RXRB	NRIP1	PCK1	NR1H3	
TNFR2 NON-CANONICAL NF-KB PATHWAY%REACTOME%R-HSA-5668541.2	TNFR2 non-canonical NF-kB pathway	TRAF3	UBA52	BIRC2	CUL1	BIRC3	UBB	UBC	RPS27A	TNFRSF1A	TNFRSF6B	TNFSF11	TNFRSF8	TNFRSF4	EDAR	TNFRSF11B	TNFRSF11A	TNFRSF17	TNFSF18	TNFSF14	TNFSF15	TNFSF12	TNFRSF9	TNFSF4	UBA3	CD27	TNFSF9	TNFSF8	EDA	TNFRSF13B	TNFRSF13C	EDA2R	TNFSF13B	EDARADD	TNFRSF12A	TNFRSF1B	LTA	TNFRSF25	LTB	CD70	CD40LG	LTBR	UBE2M	TNF	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	TNFRSF18	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	TNFSF13	TNFRSF14	TRAF2	FASLG	MAP3K14	BTRC	SKP1	NFKB2	FBXW11	RELB	
DISORDERS OF TRANSMEMBRANE TRANSPORTERS%REACTOME%R-HSA-5619115.3	Disorders of transmembrane transporters	SLC34A1	AVPR1B	AVPR1A	ABCA12	ABCG8	ABCG5	SLC9A6	NUP62	SLC9A9	CFTR	NDC1	SLC26A2	SEC13	VCP	NUP133	UBA52	SLC1A1	ABCB6	ABCB4	SEL1L	SLC5A5	NUP50	NUP54	ABCA3	CP	SLC5A1	UBB	ERLIN1	UBC	ERLIN2	SLC26A4	SLC26A3	RPS27A	RNF185	SLC36A2	ABCD1	NUP43	RAE1	SLC7A7	RANBP2	ABCC2	ABCC6	NUP35	APOA1	SLC24A1	ABCC9	SLC24A4	NUPL2	NUP37	SLC20A2	DERL3	DERL1	DERL2	RNF5	ERLEC1	SLC3A2	OS9	HK1	KCNJ11	SLC17A8	SLC24A5	SLC22A18	SLC6A20	SLC12A3	SLC12A1	SLC12A6	SLC39A4	SLC5A2	SLC2A10	ABCB11	SLC2A2	SLC16A1	RHAG	BSG	GCKR	GCK	SLC5A7	PSMD8	SLC22A12	PSMD9	PSMD6	PSMD7	SLC2A9	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	SLC22A5	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	ABCD4	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	SLC6A19	SLC6A18	PSMC5	SLC2A1	PSMC6	PSMC3	PSMC4	SLC6A14	PSMC1	PSMC2	SLC6A2	SLC6A3	SLC6A5	NUP107	NUP188	SLC27A4	NUP214	NUP210	SLCO1B1	SLCO1B3	ABCA1	NUP93	SLC35A2	SLC35A1	SLC35A3	SLC33A1	SLC35C1	SLC1A3	SLC34A2	SLCO2A1	AVP	NUP205	SLC7A9	POM121	SLC3A1	SLC29A3	AAAS	ABCC8	NUP160	NUP85	AVPR2	TPR	NUP88	NUP155	SLC40A1	HEPH	SLC17A5	NUP153	SLC4A1	SLC4A4	SLC11A2	SLC34A3	
CONJUGATION OF PHENYLACETATE WITH GLUTAMINE%REACTOME DATABASE ID RELEASE 74%177162	Conjugation of phenylacetate with glutamine	ACSM2B	ACSM1	
DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS%REACTOME%R-HSA-5609975.2	Diseases associated with glycosylation precursor biosynthesis	PMM2	DOLK	DHDDS	GLB1	GNE	GALT	DPM1	GALE	DPM2	PGM1	DPM3	GALK1	NEU1	MPI	CTSA	NUS1	GFPT1	SRD5A3	
PTK6 PROMOTES HIF1A STABILIZATION%REACTOME DATABASE ID RELEASE 74%8857538	PTK6 promotes HIF1A stabilization	EGFR	HIF1A	GPNMB	LRRK2	PTK6	HBEGF	
DOWNSTREAM SIGNALING OF ACTIVATED FGFR2%REACTOME%R-HSA-5654696.1	Downstream signaling of activated FGFR2	PTPN11	FRS2	FGF20	FRS3	FGF1	FGF23	FGF2	FGF22	FGF3	GAB1	FGF4	FGF16	FGF6	NRAS	FGF7	FGF9	PLCG1	SOS1	HRAS	FGF18	PIK3R1	PIK3CA	FGF10	
DNA STRAND ELONGATION%REACTOME DATABASE ID RELEASE 74%69190	DNA strand elongation	POLA2	DNA2	MCM7	MCM8	MCM3	MCM4	MCM5	MCM6	MCM2	RFC5	RFC3	FEN1	PCNA	RPA1	RFC4	RPA2	RFC1	LIG1	RFC2	POLD3	POLD4	RPA3	POLD1	CDC45	GINS1	POLD2	GINS2	PRIM2	GINS3	GINS4	PRIM1	POLA1	
CELL SURFACE INTERACTIONS AT THE VASCULAR WALL%REACTOME DATABASE ID RELEASE 74%202733	Cell surface interactions at the vascular wall	ITGAX	ITGA3	TNFRSF10D	ITGA6	CD47	L1CAM	JAM2	JAM3	SLC7A11	SLC7A10	SLC7A5	SLC7A6	SLC7A7	SLC7A8	SDC4	PIK3CB	SDC3	SDC1	SLC3A2	JCHAIN	PPIA	MAG	GRB7	CEACAM5	ANGPT4	ANGPT2	DOK2	GRB14	ITGB3	SLC16A1	BSG	ITGAV	TSPAN7	PICK1	ANGPT1	IGKV2-28	PTPN11	IGKV1-12	IGKV3D-20	IGKV2D-28	IGKV4-1	TEK	SHC1	IGKV2D-30	ITGAL	F11R	NRAS	IGKV3-11	PLCG1	LYN	SOS1	IGKV5-2	HRAS	INPP5D	IGHA1	SDC2	MMP1	CD84	SIRPG	VPREB3	VPREB1	SIRPA	YES1	SLC16A8	SLC16A3	CXADR	PSG1	PSG3	SELP	PSG2	MIF	FCAMR	CD44	PSG9	PSG8	PSG5	PSG4	PSG6	GYPA	GYPC	GYPB	CD99L2	PSG11	GLG1	CD99	TNFRSF10B	APOB	GP6	TNFRSF10A	SELE	SELL	GPC1	ESAM	TREM1	SPN	ITGA4	OLR1	AMICA1	ATP1B3	FCER1G	ATP1B2	CEACAM3	CD48	ATP1B1	SELPLG	EPCAM	CD58	CD74	PPIL2	TGFB1	MERTK	PTPN6	ITGB1	CD2	CEACAM1	IGLL1	CEACAM6	CD244	FN1	SLC7A9	CEACAM8	PIK3R2	ITGA5	PIK3R1	GAS6	PIK3CA	PROS1	LCK	THBD	PF4V1	CD177	CAV1	FYN	F2	ITGAM	PROCR	ITGB2	PROC	PF4	
SIGNALING BY NOTCH1%REACTOME%R-HSA-1980143.2	Signaling by NOTCH1	MIB2	MIB1	CCNC	NCSTN	NEURL1	CNTN1	MAML3	ITCH	MAMLD1	DTX4	HDAC4	UBA52	HDAC5	NOTCH1	HDAC8	HDAC9	HDAC7	CDK8	HEY1	HEY2	CUL1	UBB	UBC	HDAC10	HDAC11	RPS27A	NBEA	TBL1X	MYC	SNW1	HDAC2	HDAC1	HDAC3	TBL1XR1	HDAC6	NCOR2	DNER	NCOR1	TLE4	TLE2	TLE1	DTX1	RBX1	DTX2	ARRB1	DLK1	ARRB2	MAML2	MAML1	KAT2B	SKP1	PSEN2	RBPJ	ADAM10	KAT2A	DLL1	HEYL	DLL4	ADAM17	APH1A	NEURL1B	APH1B	CREBBP	EP300	HIF1A	HES1	NUMB	HES5	JAG2	PSENEN	PSEN1	JAG1	
PHAGOCYTE CELL DEATH CAUSED BY CYTOSOLIC MTB%REACTOME%R-HSA-9637698.1	Phagocyte cell death caused by cytosolic Mtb	
SIGNALING BY TGF-BETA RECEPTOR COMPLEX%REACTOME DATABASE ID RELEASE 74%170834	Signaling by TGF-beta Receptor Complex	CCNC	NEDD8	UBE2D1	CGN	SP1	PRKCZ	UBA52	RBL1	CBL	CDK8	F11R	E2F4	XPO1	E2F5	UBB	CCNT1	UBC	CDKN2B	RPS27A	MYC	ARHGEF18	CDK9	WWTR1	PARD3	TRIM33	PARP1	SNW1	PPP1CC	MEN1	USP9X	TFDP1	ATP1B4	TFDP2	HDAC1	SKI	PARD6A	FURIN	CCNK	PPP1R15A	RHOA	USP15	NEDD4L	MTMR4	SMAD4	PMEPA1	SMAD2	SMURF2	SMAD3	SMURF1	UCHL5	TGFB1	TGFBR1	PPP1CA	TGFBR2	SMAD7	BAMBI	STRAP	STUB1	UBE2M	FKBP1A	UBE2D3	NCOR2	PPM1A	NCOR1	PPP1CB	TGIF1	TGIF2	SKIL	CCNT2	SERPINE1	JUNB	RNF111	
PI3K AKT ACTIVATION%REACTOME%R-HSA-198203.3	PI3K AKT activation	IRS1	NGF	NTRK1	PIK3R2	PIK3R1	PIK3CA	RHOA	IRS2	PIK3CB	
REGULATED NECROSIS%REACTOME DATABASE ID RELEASE 74%5218859	Regulated Necrosis	RIPK3	TNFRSF10B	TRAF2	TNFRSF10A	FASLG	CASP8	TNFSF10	FAS	RIPK1	SDCBP	FADD	PELI1	UBA52	BIRC2	CDC37	PDCD6IP	BIRC3	STUB1	UBB	MLKL	UBC	OGT	RPS27A	FLOT1	FLOT2	HSP90AA1	XIAP	TRADD	
RA BIOSYNTHESIS PATHWAY%REACTOME%R-HSA-5365859.2	RA biosynthesis pathway	ALDH1A1	RDH14	RDH13	RDH16	ALDH8A1	RDH5	ADH1C	ADH1A	AKR1C3	CRABP1	DHRS4	ALDH1A3	CYP26A1	ADH4	SDR16C5	DHRS9	DHRS3	CYP26B1	RDH11	CYP26C1	ALDH1A2	RDH10	
THROMBOXANE SIGNALLING THROUGH TP RECEPTOR%REACTOME%R-HSA-428930.2	Thromboxane signalling through TP receptor	GNGT1	GNGT2	AAMP	GNG12	GNG11	GNG13	GNA14	GNB2	GNA15	GNA11	GNB1	GNG3	GNAQ	GNB4	GNA13	GNG10	GNB3	GNG2	GNB5	GNG5	GNG4	GNG7	GNG8	TBXA2R	
AUTODEGRADATION OF CDH1 BY CDH1:APC C%REACTOME%R-HSA-174084.3	Autodegradation of Cdh1 by Cdh1:APC C	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	ANAPC4	ANAPC5	PSMB6	PSMB7	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	FZR1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	PSMC2	UBE2S	CDC16	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
DEFECTIVE SLC2A10 CAUSES ARTERIAL TORTUOSITY SYNDROME (ATS)%REACTOME DATABASE ID RELEASE 74%5619068	Defective SLC2A10 causes arterial tortuosity syndrome (ATS)	SLC2A10	
REGULATION OF TLR BY ENDOGENOUS LIGAND%REACTOME%R-HSA-5686938.3	Regulation of TLR by endogenous ligand	LY96	S100A1	APOB	FGB	FGA	TLR1	S100A9	S100A8	CD14	TLR4	FGG	TLR6	TLR2	HMGB1	LBP	CD36	
DEFECTIVE CYP17A1 CAUSES ADRENAL HYPERPLASIA 5 (AH5)%REACTOME%R-HSA-5579028.3	Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)	CYP17A1	
SORAFENIB-RESISTANT PDGFR MUTANTS%REACTOME DATABASE ID RELEASE 74%9674404	Sorafenib-resistant PDGFR mutants	PDGFRA	
DISEASES OF MISMATCH REPAIR (MMR)%REACTOME DATABASE ID RELEASE 74%5423599	Diseases of Mismatch Repair (MMR)	MSH6	PMS2	MSH2	MSH3	MLH1	
THYROXINE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%209968	Thyroxine biosynthesis	DUOX1	TPO	IYD	SLC5A5	DIO1	DIO2	DIO3	CGA	DUOX2	TSHB	
SHC1 EVENTS IN ERBB4 SIGNALING%REACTOME%R-HSA-1250347.3	SHC1 events in ERBB4 signaling	NRG1	NRAS	NRG2	NRG3	SOS1	NRG4	HRAS	EREG	BTC	SHC1	HBEGF	
PDGFR MUTANTS BIND TKIS%REACTOME DATABASE ID RELEASE 74%9674428	PDGFR mutants bind TKIs	PDGFRA	
REGULATION OF GENE EXPRESSION BY HYPOXIA-INDUCIBLE FACTOR%REACTOME%R-HSA-1234158.2	Regulation of gene expression by Hypoxia-inducible Factor	ARNT	HIF3A	CITED2	HIGD1A	VEGFA	CREBBP	CA9	EP300	HIF1A	EPO	EPAS1	
ELASTIC FIBRE FORMATION%REACTOME%R-HSA-1566948.1	Elastic fibre formation	LOXL2	ITGB5	EFEMP2	EFEMP1	BMP7	GDF5	BMP4	MFAP5	MFAP4	LOX	MFAP1	ITGB8	MFAP3	MFAP2	ITGB6	ITGA8	TGFB1	ITGB1	VTN	ITGA5	FBN1	ITGB3	BMP2	TGFB2	ITGAV	TGFB3	FBN2	FBN3	BMP10	ELN	LOXL3	LTBP4	LOXL4	FBLN1	LTBP2	FURIN	LTBP3	FBLN2	LTBP1	FBLN5	LOXL1	
EXPRESSION AND PROCESSING OF NEUROTROPHINS%REACTOME DATABASE ID RELEASE 74%9036866	Expression and Processing of Neurotrophins	PCSK5	NGF	FURIN	PCSK6	
APOPTOSIS INDUCED DNA FRAGMENTATION%REACTOME%R-HSA-140342.3	Apoptosis induced DNA fragmentation	HIST1H1D	KPNA1	HIST1H1E	KPNB1	HIST1H1A	HIST1H1B	HIST1H1C	DFFB	DFFA	HMGB1	CASP3	H1F0	HMGB2	
KERATINIZATION%REACTOME DATABASE ID RELEASE 74%6805567	Keratinization	KRT24	KRT23	KRT20	KRT28	KRT27	KRT26	FLG	KRTAP27-1	KRT25	KRTAP9-7	KRTAP5-10	KRTAP9-6	KRTAP5-11	KRTAP9-4	KRTAP9-3	KRTAP9-2	KRTAP16-1	KRTAP9-1	JUP	KRT35	KRT34	KRT32	KRT31	KRTAP9-9	KRTAP9-8	KRT39	KRT38	KRT37	KRT36	SPRR3	CSTA	CASP14	KRT13	KRT12	KRT10	KRT19	KRT18	KRT17	KRT16	KRT15	KRT14	KRTAP24-1	KRT6C	KRT6B	KRT6A	KRTAP25-1	KRT71	KRTAP13-2	KRTAP13-1	KRTAP2-4	KRTAP13-4	KRTAP2-3	KRTAP13-3	KRTAP2-2	KRT79	KRT78	KRTAP2-1	KAZN	KRT77	KRT76	KRT75	KRT74	KRT73	LOR	KRT72	KRT40	PKP2	PKP1	PKP4	PKP3	DSC1	DSC2	DSC3	KRTAP22-1	KRTAP4-4	KRTAP11-1	KRTAP4-3	KRTAP4-2	KRTAP4-1	KRTAP4-9	KRTAP4-8	KRT82	KRTAP4-7	KRT81	KRTAP4-6	KRT80	KRTAP4-5	KRT86	KRT85	KRT84	KRT83	DSP	DSG1	DSG2	DSG3	DSG4	KRTAP29-1	KRTAP6-2	KRTAP6-1	KRTAP6-3	EVPL	KRTAP8-1	PERP	KLK13	KLK14	KLK12	TGM1	TGM5	SPINK6	SPINK5	SPINK9	KRTAP23-1	LELP1	KRTAP12-1	KRTAP12-3	KRTAP12-2	KRTAP12-4	TCHH	KRTAP10-1	CELA2A	KRTAP21-2	KRTAP21-3	KRTAP10-3	KRTAP10-2	KRTAP10-5	KRTAP10-4	KRTAP10-7	KRTAP10-6	KRTAP10-9	KRTAP10-8	KRTAP21-1	LCE1A	LCE1B	PRSS8	KRTAP17-1	LCE1E	LCE1F	LCE1C	LCE1D	LCE2B	LCE2C	LCE2A	KRTAP4-11	ST14	KRTAP26-1	LCE5A	KRTAP1-5	KRTAP1-4	KRTAP1-3	KRTAP1-1	KRTAP15-1	LCE6A	IVL	CAPNS1	LCE2D	LCE3C	LCE3D	LCE3A	LCE3B	LCE3E	LCE4A	CAPN1	KRTAP3-3	KRTAP3-2	KRTAP3-1	RPTN	PI3	KRTAP5-3	PCSK6	KRTAP5-2	KRTAP5-1	KRTAP5-9	KRTAP5-8	KRTAP5-7	KRTAP5-6	KRTAP5-5	KRTAP5-4	KRTAP19-2	KRTAP19-1	KRTAP19-4	KRTAP19-3	KRTAP19-6	KRTAP19-5	KRTAP19-8	KRTAP19-7	FURIN	KRT4	KRT3	KRT2	KRT1	KRT8	KRT7	KRT5	KRT9	KRTAP20-1	KRTAP20-2	SPRR2E	SPRR2F	SPRR2G	KRTAP10-10	KRTAP10-11	KRTAP10-12	KLK5	PPL	KLK8	KRT33B	KRT33A	SPRR2A	SPRR2B	SPRR2D	CDSN	LIPJ	SPRR1A	LIPN	LIPM	SPRR1B	LIPK	
REGULATION OF NECROPTOTIC CELL DEATH%REACTOME%R-HSA-5675482.4	Regulation of necroptotic cell death	RIPK3	TNFRSF10B	TRAF2	TNFRSF10A	FASLG	CASP8	TNFSF10	FAS	RIPK1	SDCBP	FADD	PELI1	UBA52	BIRC2	CDC37	PDCD6IP	BIRC3	STUB1	UBB	MLKL	UBC	OGT	RPS27A	FLOT1	FLOT2	HSP90AA1	XIAP	TRADD	
DEFECTIVE SLC26A4 CAUSES PENDRED SYNDROME (PDS)%REACTOME DATABASE ID RELEASE 74%5619046	Defective SLC26A4 causes Pendred syndrome (PDS)	SLC26A4	
FORMATION OF THE ACTIVE COFACTOR, UDP-GLUCURONATE%REACTOME%R-HSA-173599.1	Formation of the active cofactor, UDP-glucuronate	UGP2	SLC35D1	UGDH	
REGULATION OF MITOTIC CELL CYCLE%REACTOME DATABASE ID RELEASE 74%453276	Regulation of mitotic cell cycle	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	SKP2	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	PSMB10	PSMA7	ANAPC4	CUL1	AURKB	PSMA8	AURKA	ANAPC5	PSMB6	PSMB7	CCNB1	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	FZR1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	PSMC2	UBE2S	PLK1	CDC16	CDK2	CDK1	RB1	PTTG1	CDC14A	FBXO5	BUB1B	CDC20	BUB3	MAD2L1	NEK2	BTRC	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
DEFECTIVE PGM1 CAUSES PGM1-CDG (CDG1T)%REACTOME%R-HSA-5609974.2	Defective PGM1 causes PGM1-CDG (CDG1t)	PGM1	
FCGR3A-MEDIATED PHAGOCYTOSIS%REACTOME DATABASE ID RELEASE 74%9664422	FCGR3A-mediated phagocytosis	MAPK3	IGKV2-28	IGKV1-12	IGKV3D-20	IGKV2D-28	ABL1	IGKV4-1	IGKV2D-30	IGKV3-11	LYN	IGKV5-2	HCK	MAPK1	CD3G	CYFIP2	NCKAP1	FCGR3A	CYFIP1	RAC1	WIPF1	YES1	ARPC1B	FGR	WIPF2	ARPC1A	VAV1	WIPF3	BRK1	WASL	ACTB	DOCK1	ACTG1	NCK1	ACTR3	VAV3	ACTR2	CDC42	VAV2	MYH2	ELMO1	BTK	ELMO2	WAS	NCKIPSD	NCKAP1L	WASF1	WASF2	WASF3	MYO10	MYO5A	ARPC4	MYO9B	ARPC5	BAIAP2	MYO1C	ABI2	ARPC2	ARPC3	ABI1	MYH9	IGHG4	IGHG1	IGHG2	SYK	CRK	FYN	PTK2	
DNA REPLICATION%REACTOME DATABASE ID RELEASE 74%69306	DNA Replication	MCM7	MCM8	UBE2D1	CDC23	CDC26	CDC27	SKP2	CDC7	ANAPC7	UBA52	UBE2E1	CCNA2	CCNA1	CCNE2	CCNE1	MCM3	MCM4	ANAPC4	CUL1	MCM5	ANAPC5	MCM6	ANAPC1	UBB	MCM2	ANAPC2	ANAPC15	ANAPC16	UBC	ANAPC10	ANAPC11	ORC5	ORC4	RPS27A	FZR1	ORC6	ORC1	ORC3	ORC2	CDT1	UBE2C	CDC6	UBE2S	RPA1	CDC16	RPA2	CDK2	RPA3	PRIM2	PRIM1	POLA1	POLA2	DNA2	GMNN	MCM10	DBF4	RPA4	RFC5	RFC3	FEN1	PCNA	RFC4	RFC1	LIG1	RFC2	POLE4	POLD3	POLD4	PSMD8	POLE2	POLD1	PSMD9	CDC45	PSMD6	GINS1	POLE3	PSMD7	POLD2	GINS2	PSMD4	POLE	GINS3	PSMD5	GINS4	PSMD2	PSMD3	PSMD1	E2F1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	E2F2	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	E2F3	RBX1	SKP1	
SCAVENGING BY CLASS H RECEPTORS%REACTOME DATABASE ID RELEASE 74%3000497	Scavenging by Class H Receptors	APOB	STAB1	SPARC	STAB2	
PP2A-MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS%REACTOME DATABASE ID RELEASE 74%163767	PP2A-mediated dephosphorylation of key metabolic factors	PPP2CA	PPP2CB	PFKFB1	PPP2R1A	PPP2R1B	MLXIPL	PPP2R5D	
G BETA:GAMMA SIGNALLING THROUGH PI3KGAMMA%REACTOME%R-HSA-392451.3	G beta:gamma signalling through PI3Kgamma	GNG12	GNG11	GNG13	RHOA	GNB2	GNB1	GNB4	GNB3	PDPK1	GNB5	AKT2	AKT3	GNGT1	AKT1	GNGT2	PIK3CG	PIK3R5	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	PIK3R6	
VITAMIN C (ASCORBATE) METABOLISM%REACTOME%R-HSA-196836.2	Vitamin C (ascorbate) metabolism	CYB5A	CYB5R3	GSTO2	SLC23A1	SLC2A1	SLC2A3	GSTO1	SLC23A2	
SNRNP ASSEMBLY%REACTOME DATABASE ID RELEASE 74%191859	snRNP Assembly	NUP62	NDC1	SEC13	TGS1	NUP133	NUP50	NUP54	SNRPD2	SNRPD1	SNRPD3	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	NUP107	NUP188	NUP214	NUP210	NUP93	NUP205	POM121	AAAS	SNRPG	NUP160	PRMT5	NCBP1	NUP85	NCBP2	SNRPE	TPR	SNRPF	NUP88	SNRPB	NUP155	GEMIN2	PHAX	WDR77	NUP153	CLNS1A	GEMIN4	GEMIN5	GEMIN6	GEMIN7	GEMIN8	DDX20	SMN2	SMN1	SNUPN	
ABO BLOOD GROUP BIOSYNTHESIS%REACTOME%R-HSA-9033807.1	ABO blood group biosynthesis	FUT2	FUT1	
POU5F1 (OCT4), SOX2, NANOG REPRESS GENES RELATED TO DIFFERENTIATION%REACTOME DATABASE ID RELEASE 74%2892245	POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	SOX2	NANOG	POU5F1	
NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY%REACTOME%R-HSA-5674499.1	Negative feedback regulation of MAPK pathway	RAF1	MAPK3	MAPK1	BRAF	MAP2K1	MAP2K2	
FGFR1B LIGAND BINDING AND ACTIVATION%REACTOME%R-HSA-190370.2	FGFR1b ligand binding and activation	FGF1	FGF10	FGF2	FGF22	FGF3	
ALPHA-OXIDATION OF PHYTANATE%REACTOME%R-HSA-389599.2	Alpha-oxidation of phytanate	PECR	PHYH	SLC25A17	HACL1	SLC27A2	
HS-GAG BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%2022928	HS-GAG biosynthesis	SLC35D2	AGRN	GPC1	HS3ST5	HS3ST6	HS3ST4	HS3ST1	HS3ST2	HS6ST1	SDC2	HS6ST2	HS6ST3	NDST2	NDST1	NDST4	NDST3	GLCE	HS3ST3A1	SDC4	SDC3	GPC3	SDC1	GPC2	GPC5	GPC4	HSPG2	EXT1	GPC6	EXT2	HS2ST1	HS3ST3B1	
MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS%REACTOME DATABASE ID RELEASE 74%174490	Membrane binding and targetting of GAG proteins	VPS37C	RPS27A	VPS37D	VPS37A	VPS37B	UBAP1	UBA52	VPS28	NMT2	UBB	TSG101	UBC	MVB12B	MVB12A	
POTASSIUM CHANNELS%REACTOME DATABASE ID RELEASE 74%1296071	Potassium Channels	KCNA3	KCNA4	KCNA5	KCNA6	KCNA7	KCNJ1	GNG12	KCNB1	GNG11	KCNB2	GNG13	KCNJ14	KCNS1	KCNS2	KCNS3	KCNK1	KCNK2	GNB2	KCNK3	HCN2	GNB1	KCNK4	HCN1	GNB4	GNB3	GNB5	ABCC9	KCNJ11	KCNJ2	KCNJ3	KCNJ4	GABBR2	KCNJ5	KCNJ6	GABBR1	KCNJ10	KCNJ12	KCNJ9	KCNJ15	KCNJ16	KCNK13	KCNQ2	KCNQ3	KCNG1	KCNG2	KCNG3	KCNG4	KCNH1	KCNH2	KCNH3	KCNH4	KCNH5	KCNH6	KCNK10	KCNH7	KCNJ8	KCNH8	ABCC8	KCNK16	KCNK17	KCNK18	KCNQ1	KCNQ4	GNGT1	KCNQ5	KCNV1	KCNV2	GNGT2	KCNMB1	KCNMB2	KCNMB3	KCNN1	KCNMB4	KCNN2	KCNN3	KCNN4	KCNF1	KCNK6	KCNK7	KCNC1	KCNK9	KCNC2	KCNC3	GNG3	GNG10	KCNC4	KCND1	KCND2	GNG2	KCND3	KCNAB1	GNG5	KCNAB2	GNG4	KCNAB3	GNG7	KCNMA1	GNG8	KCNA10	HCN4	HCN3	KCNA1	KCNA2	
DEFECTIVE ACTH CAUSES OBESITY AND PRO-OPIOMELANOCORTININ DEFICIENCY (POMCD)%REACTOME DATABASE ID RELEASE 74%5579031	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)	POMC	MC2R	
MITOCHONDRIAL CALCIUM ION TRANSPORT%REACTOME%R-HSA-8949215.2	Mitochondrial calcium ion transport	SLC8B1	SLC8A3	PHB	STOML2	CCDC109B	SPG7	PHB2	PARL	AFG3L2	C2orf47	SMDT1	PMPCB	YME1L1	PMPCA	MICU3	LETM1	MICU2	VDAC3	MICU1	AKAP1	VDAC2	MCU	VDAC1	
TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53-DEPENDENT APOPTOSIS REMAIN UNCERTAIN%REACTOME%R-HSA-6803205.1	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	TP53I3	PERP	BCL6	PPP1R13B	TP63	RABGGTB	RABGGTA	TP53BP2	BIRC5	TP73	NDRG1	CHM	BCL2L14	TP53	
RET SIGNALING%REACTOME DATABASE ID RELEASE 74%8853659	RET signaling	RET	PRKCA	PTPN11	GFRA1	GAB2	SHC1	PSPN	GFRA3	GRB7	PDLIM7	GAB1	GFRA2	DOK2	PLCG1	GFRA4	GDNF	RAP1GAP	SOS1	PIK3R3	PIK3R2	PIK3R1	DOK1	PIK3CA	DOK4	PRKACG	DOK5	MAPK7	PRKACB	DOK6	PRKACA	FRS2	PIK3CD	IRS2	PIK3CB	GRB10	NRTN	ARTN	SHC3	
FBXW7 MUTANTS AND NOTCH1 IN CANCER%REACTOME DATABASE ID RELEASE 74%2644605	FBXW7 Mutants and NOTCH1 in Cancer	SKP1	RBX1	CUL1	NOTCH1	
DECTIN-1 MEDIATED NONCANONICAL NF-KB SIGNALING%REACTOME%R-HSA-5607761.1	Dectin-1 mediated noncanonical NF-kB signaling	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	CUL1	RELA	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	UBA3	UBE2M	MAP3K14	BTRC	PSMD8	SKP1	NFKB2	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	FBXW11	PSMD2	PSMD3	PSMD1	RELB	CHUK	PSMA5	
CARBOXYTERMINAL POST-TRANSLATIONAL MODIFICATIONS OF TUBULIN%REACTOME DATABASE ID RELEASE 74%8955332	Carboxyterminal post-translational modifications of tubulin	TTL	TPGS2	TUBB8	TUBA3E	TUBA1C	TUBB6	TUBA1B	TUBB3	TUBB1	AGTPBP1	LRRC49	NICN1	TTLL7	AGBL5	AGBL4	TTLL6	TTLL5	TUBB2B	TTLL4	TUBB2A	TTLL3	AGBL1	TTLL2	AGBL3	TTLL1	AGBL2	TTLL11	TTLL12	TTLL9	TTLL8	TUBA1A	TUBB4B	TUBB4A	TTLL10	TUBB8P12	TPGS1	
TRANSCRIPTIONAL ACTIVATION OF CELL CYCLE INHIBITOR P21%REACTOME DATABASE ID RELEASE 74%69895	Transcriptional activation of cell cycle inhibitor p21	CDKN1A	ZNF385A	PCBP4	TP53	
MPS II - HUNTER SYNDROME%REACTOME DATABASE ID RELEASE 74%2206296	MPS II - Hunter syndrome	IDS	
MYD88 DEPENDENT CASCADE INITIATED ON ENDOSOME%REACTOME DATABASE ID RELEASE 74%975155	MyD88 dependent cascade initiated on endosome	RPS6KA1	RIPK2	MAPK3	IRAK4	FOS	CREB1	DUSP4	TRAF6	IRF7	PELI1	UBA52	TLR7	UBE2V1	DUSP6	DUSP7	CUL1	RELA	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	TLR9	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	TICAM2	LY96	TICAM1	CD14	TLR4	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	AGER	BTRC	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
NEGATIVE REGULATION OF MAPK PATHWAY%REACTOME DATABASE ID RELEASE 74%5675221	Negative regulation of MAPK pathway	MAPK3	RAF1	DUSP4	MAPK12	DUSP5	DUSP2	DUSP1	MARK3	UBA52	DUSP8	PTPN7	PTPN3	YWHAB	DUSP9	NRAS	DUSP6	DUSP7	HRAS	UBB	UBC	RPS27A	PPP2CA	ARAF	PPP2CB	DUSP16	MAPK1	PPP2R1A	DUSP10	PAQR3	PEBP1	PPP2R5E	KSR1	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	BRAP	PPP2R1B	BRAF	MAP2K1	MAP2K2	PPP5C	
BDNF ACTIVATES NTRK2 (TRKB) SIGNALING%REACTOME%R-HSA-9024909.1	BDNF activates NTRK2 (TRKB) signaling	BDNF	NTRK2	
MAP3K8 (TPL2)-DEPENDENT MAPK1 3 ACTIVATION%REACTOME DATABASE ID RELEASE 74%5684264	MAP3K8 (TPL2)-dependent MAPK1 3 activation	MAP2K4	NFKB1	RPS27A	TNIP2	MAP3K8	BTRC	UBA52	SKP1	IKBKB	CUL1	FBXW11	UBB	MAP2K1	UBC	IKBKG	CHUK	
NEURODEGENERATIVE DISEASES%REACTOME DATABASE ID RELEASE 74%8863678	Neurodegenerative Diseases	LMNB1	FASLG	CAPNS1	FOXO3	BCL2L11	CAPNS2	CDC25A	CAPN2	CAPN1	CAST	CDK5R1	CDC25C	PRDX2	JUN	PRDX1	SOD2	CDC25B	CDK5	GOLGA2	APP	YWHAE	
PKA-MEDIATED PHOSPHORYLATION OF CREB%REACTOME%R-HSA-111931.1	PKA-mediated phosphorylation of CREB	ADCY2	NBEA	ADCY1	ADCY8	ADCY7	ADCY6	CREB1	ADCY9	ADCY5	PRKAR1B	PRKAR1A	PRKX	PRKAR2A	PRKACA	PRKAR2B	ADCY4	PRKACG	ADCY3	PRKACB	
RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL%REACTOME%R-HSA-6790901.4	rRNA modification in the nucleus and cytosol	NOP2	EMG1	UTP20	NOP14	RCL1	NOP10	DDX49	DDX47	WDR3	UTP15	DDX52	UTP18	BMS1	DCAF13	NOP56	NOP58	KRR1	RPS2	FCF1	THUMPD1	PWP2	RRP9	IMP3	WDR75	IMP4	CIRH1A	RRP7A	PDCD11	GAR1	WBSCR22	DHX37	PNO1	TBL3	MPHOSPH10	NOL11	NAT10	WDR46	WDR43	TRMT112	RPS14	UTP14A	UTP14C	WDR36	DIEXF	NHP2L1	TSR3	HEATR1	NOC4L	NOL6	RPS9	RRP36	UTP6	RPS7	UTP3	RPS6	FBL	DIMT1	UTP11L	DKC1	NHP2	
PROTEIN LOCALIZATION%REACTOME DATABASE ID RELEASE 74%9609507	Protein localization	TIMM9	TIMM13	TIMM10	DDO	ASNA1	PEX16	ATAD1	UBE2D1	UBL4A	EMD	TIMM8B	TIMM8A	SGTA	HMOX1	GDAP1	UBA52	GFER	NUDT7	VAPA	TOMM70A	TOMM7	CRAT	TOMM5	TOMM6	UBB	VDAC1	UBC	RPS27A	ABCD2	IDH3G	ABCD3	ABCD1	CS	PEX3	ACO2	SLC25A4	USP9X	SLC25A6	SCP2	PEX19	PMPCB	PEX2	PMPCA	COX19	PEX10	CYC1	PEX12	PEX13	PEX14	EPHX2	STX5	SERP1	UBE2D2	PECR	PHYH	NDUFB8	SLC25A17	HACL1	SLC27A2	ACOT8	EHHADH	HSD17B4	DECR2	ACAA1	ACOT4	STX1A	OTC	ATP5A1	ATP5G1	HSPD1	ATP5B	IDH1	SAMM50	CHCHD3	ZFAND6	TOMM20	PEX26	TOMM22	HSPA9	CHCHD4	VAMP2	CHCHD5	MTX1	CHCHD2	CHCHD7	MTX2	NUDT19	LONP2	MPV17	GSTK1	CMC4	CMC2	ECH1	PAM16	PIPOX	BCS1L	GNPAT	ACOT2	PEX11B	COX17	TIMM50	BAG6	PITRM1	GRPEL1	LDHD	GRPEL2	OTOF	HAO1	HAO2	COA4	DNAJC19	FIS1	APP	ACBD5	TYSND1	NOS2	UBE2D3	CHCHD10	TIMM44	TIMM10B	COQ2	DAO	AMACR	PXMP2	PXMP4	HSCB	IDE	CROT	SEC61G	TIMM17A	TIMM17B	SEC61B	COA6	CAT	GET4	PRNP	CAMLG	TIMM23	TIMM22	PEX1	HMGCL	TIMM21	BAAT	PEX7	ACOX2	ACOX1	PEX6	AGPS	ACOX3	DHRS4	TAZ	SLC25A12	AGXT	FXN	PAOX	SLC25A13	TOMM40	WRB	
ELEVATION OF CYTOSOLIC CA2+ LEVELS%REACTOME DATABASE ID RELEASE 74%139853	Elevation of cytosolic Ca2+ levels	P2RX2	TRPC7	P2RX1	P2RX7	ORAI2	ORAI1	TRPC6	P2RX4	TRPC3	ITPR1	ITPR2	ITPR3	P2RX6	P2RX5	STIM1	P2RX3	
ORC1 REMOVAL FROM CHROMATIN%REACTOME%R-HSA-68949.3	Orc1 removal from chromatin	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	MCM7	PSME3	MCM8	PSME4	PSME1	PSME2	PSMD10	SKP2	PSMB11	UBA52	PSMD12	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	PSMB10	MCM3	MCM4	PSMA7	CUL1	MCM5	PSMA8	PSMB6	MCM6	PSMB7	PSMB4	UBB	MCM2	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	ORC5	PSMB8	ORC4	RPS27A	PSMB9	ORC6	ORC1	PSMC5	ORC3	PSMC6	ORC2	PSMC3	CDT1	PSMC4	PSMC1	CDC6	PSMC2	CDK2	RBX1	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
VISUAL PHOTOTRANSDUCTION%REACTOME DATABASE ID RELEASE 74%2187338	Visual phototransduction	PDE6G	LRP1	LRP2	PRKCQ	GNAT1	GNB1	NMT1	AWAT2	NMT2	ABCA4	OPN1SW	OPN1MW	OPN1LW	RBP3	OPN1MW2	DHRS3	RLBP1	SDC2	APOA2	APOA1	APOA4	SLC24A1	SDC4	SDC3	GPC3	SDC1	GPC2	GPC5	FNTA	GPC4	SDR9C7	GPC6	FNTB	MYO7A	HSD17B6	RPE65	RBP4	PLB1	TTR	LPL	RDH12	DHRS9	RDH11	GUCA1B	CYP4V2	GUCA1A	RDH10	GUCA1C	HSD17B1	CNGA1	RBP1	APOE	CAMKMT	APOB	NAPEPLD	AGRN	RBP2	RDH16	LDLR	RGS9BP	RDH5	GPC1	LRAT	PRKCA	SAG	GPIHBP1	PPEF1	STRA6	GUCY2D	RETSAT	GUCY2F	LRP8	GRK1	APOC3	APOM	GRK7	BCO2	BCO1	APOC2	RCVRN	AKR1C1	AKR1C4	AKR1B10	LRP10	METAP1	LRP12	METAP2	GNGT1	RHO	HSPG2	CNGB1	AKR1C3	CLPS	PDE6B	PNLIP	PDE6A	
EVASION OF ONCOGENE INDUCED SENESCENCE DUE TO P14ARF DEFECTS%REACTOME DATABASE ID RELEASE 74%9646303	Evasion of Oncogene Induced Senescence Due to p14ARF Defects	CDKN2A	
TRANSCRIPTIONAL REGULATION BY RUNX2%REACTOME DATABASE ID RELEASE 74%8878166	Transcriptional regulation by RUNX2	SKP2	ABL1	UBA52	UCMA	PPARGC1A	HEY1	CUL1	HEY2	CCNB1	UBB	UBC	RPS27A	MAPK1	CDK1	WWP1	COL1A1	SMAD4	SMURF1	IHH	STUB1	MAF	DLX5	ESRRA	DLX6	STAT1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	ZNF521	PSMA6	PSMA3	MAPK3	CDKN1A	PSMA4	PSMA1	CBFB	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	HDAC4	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	SP7	PSMB10	PSMA7	NKX3-2	PSMA8	PSMB6	HAND2	PSMB7	PPM1D	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	SOX9	PSMC3	PSMC4	PSMC1	WWTR1	PSMC2	TWIST2	TWIST1	YES1	LGALS3	MMP13	RB1	ESR1	SMAD1	HDAC3	SMAD6	YAP1	SRC	NR3C1	HDAC6	BAX	HIVEP3	ITGBL1	SATB2	BGLAP	ITGA5	AKT2	AKT3	MSX2	RUNX1	AKT1	RBX1	BMP2	RBM14	GSK3B	CCND1	CDK4	SKP1	AR	GLI3	GLI2	HES1	PPARGC1B	
EICOSANOIDS%REACTOME DATABASE ID RELEASE 74%211979	Eicosanoids	CYP4A22	CYP4F2	CYP4F3	PTGIS	CYP4B1	TBXAS1	CYP4F11	CYP4F8	CYP4F12	CYP8B1	CYP4F22	CYP4A11	
IONOTROPIC ACTIVITY OF KAINATE RECEPTORS%REACTOME DATABASE ID RELEASE 74%451306	Ionotropic activity of kainate receptors	DLG1	DLG3	DLG4	GRIK5	GRIK3	GRIK4	GRIK1	GRIK2	NCALD	
LRR FLII-INTERACTING PROTEIN 1 (LRRFIP1) ACTIVATES TYPE I IFN PRODUCTION%REACTOME DATABASE ID RELEASE 74%3134973	LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	CTNNB1	IRF3	CREBBP	EP300	LRRFIP1	
BRANCHED-CHAIN AMINO ACID CATABOLISM%REACTOME DATABASE ID RELEASE 74%70895	Branched-chain amino acid catabolism	BCKDHA	ACAD8	MCCC2	HIBADH	HSD17B10	BCKDHB	MCCC1	PPM1K	ACADSB	BCKDK	DLD	ALDH6A1	AUH	IVD	DBT	ECHS1	BCAT1	ACAT1	SLC25A44	HIBCH	BCAT2	
DEFECTIVE OGG1 SUBSTRATE BINDING%REACTOME DATABASE ID RELEASE 74%9656255	Defective OGG1 Substrate Binding	OGG1	
AMINO ACID AND DERIVATIVE METABOLISM%REACTOME DATABASE ID RELEASE 74%71291	Amino acid and derivative metabolism	TSTD1	SECISBP2	HOGA1	GCAT	ASRGL1	MTAP	ETHE1	IDO2	HPD	ALDH7A1	IDO1	LIPT2	UBA52	TPH2	LIPT1	GCDH	SLC45A2	SHMT1	SDSL	LIAS	OAZ1	SLC5A5	OAZ2	OAZ3	ACMSD	AFMID	NAALAD2	RIMKLA	RIMKLB	PYCR1	PYCR2	TYR	GLUD1	GLUD2	BHMT	RPS27A	HAL	ADI1	GPT	CSAD	ADO	DLAT	SLC7A5	ENOPH1	AASS	BHMT2	OCA2	OAT	SLC25A10	HAAO	HDC	ODC1	HRSP12	CARNS1	NQO1	AADAT	BBOX1	FAH	AGMAT	SLC3A2	GNMT	CCBL2	CCBL1	HNMT	SAT1	HGD	KMO	FOLH1	SMS	ASMT	SLC36A4	MRI1	AANAT	AMDHD1	MPST	EEFSEC	GLS	PDHA2	PDHA1	GOT1	GOT2	AZIN2	RPL4	AZIN1	QDPR	GRHPR	RPL5	ASNS	SEPSECS	RPL30	PYCRL	RPL3	TAT	RPL32	AMD1	RPL31	GADL1	RPL34	SQRDL	RPL10L	FTCD	RPL8	DHTKD1	RPL10A	KYNU	RPL9	PSTK	RPL6	AMT	RPL7	ECHS1	INMT	RPS15	DCT	RPS14	TST	RPS17	CHDH	RPS16	ASPG	RPL18A	NAT8L	RPS19	ASPA	RPL36AL	ALDH9A1	RPS18	TYRP1	RPL36	PDHB	RPL35	SRM	RPL38	CBS	RPL37	PCBD1	RPS11	SLC25A21	RPL39	CRYM	RPS10	C9orf41	RPS13	SUOX	RPS12	GSTZ1	RPS9	TMLHE	RPL21	UROC1	RPS7	CTH	SARDH	RPS8	SCLY	RPL23	CDO1	RPS5	RPL22	PSMD8	RPS6	RPSA	PSMD9	RPL24	PSMD6	RPL27	PSMD7	RPL26	PSMD4	RPL29	PSMD5	RPL28	PSMD2	RPS4Y2	PSMD3	RPS4Y1	PSMD1	PNMT	RPL39L	DDC	TH	PSMA5	RPL41	PSMA6	DBH	PSMA3	MTRR	RPL3L	PSMA4	RPS26	PSMA1	NNMT	RPS25	PSMA2	AHCY	PSME3	RPS28	PSME4	PSME1	RPS27	MTR	PSME2	RPS29	RPL27A	MAT1A	RPS20	PSMD10	RPS21	PSMB11	RPS24	PSMD12	RPS23	PSMD11	RPLP1	PSMD14	HSD17B10	RPLP0	PSMD13	RPS4X	RPL7A	PSMB10	RPLP2	PSMA7	PSMA8	RPL13A	GLS2	PSMB6	RPS3A	PSMB7	RPL37A	RPL10	PSMB4	RPL12	PSMB5	TXNRD1	RPL11	PSMB2	PSMB3	RPL36A	RPS27L	PSMB1	PSMF1	RPS15A	RPL14	SHFM1	GAMT	RPS3	PSMB8	CKMT2	RPL13	PSMB9	GATM	SLC6A8	RPL15	RPS2	CKM	PSMC5	NDUFAB1	RPL18	CKMT1A	PSMC6	CKMT1B	RPL17	PSMC3	CKB	PSMC4	PSMC1	RPL19	PSMC2	SLC6A12	RPL35A	SLC6A11	RPL23A	SLC6A7	TXN2	RPL22L1	FAU	RPL26L1	PIPOX	PAH	HAO1	DAO	PXMP2	SLC44A1	ACAT1	SLC25A12	AGXT	PAOX	SLC25A13	DDO	ALDH4A1	PRODH	PRODH2	DUOX1	TPO	IYD	DIO1	DIO2	DIO3	DUOX2	DLST	OGDH	DLD	APIP	PAPSS1	AGXT2	GLUL	BCKDHA	ACAD8	MCCC2	HIBADH	PHYKPL	BCKDHB	SRR	MCCC1	PSAT1	SERINC1	PPM1K	ACADSB	PHGDH	SERINC3	BCKDK	ALDH6A1	SERINC2	AUH	PSPH	IVD	SERINC5	SERINC4	DBT	BCAT1	SLC25A44	HIBCH	BCAT2	SLC25A15	ARG2	SLC25A2	CPS1	ARG1	ASL	NAGS	ASS1	NMRAL1	OTC	CGA	DARS	SARS	EPRS	AIMP1	AIMP2	QARS	KARS	LARS	MARS	RARS	IARS	EEF1E1	TSHB	TPH1	DMGDH	GLDC	PAPSS2	GCSH	IL4I1	HYKK	TDO2	PDHX	SDS	
ACTIVATION OF CASPASES THROUGH APOPTOSOME-MEDIATED CLEAVAGE%REACTOME%R-HSA-111459.3	Activation of caspases through apoptosome-mediated cleavage	APAF1	XIAP	CASP9	CASP3	CASP7	CYCS	
SEMA4D IN SEMAPHORIN SIGNALING%REACTOME%R-HSA-400685.2	Sema4D in semaphorin signaling	ARHGEF11	RRAS	ARHGEF12	ROCK1	SEMA4D	ROCK2	LIMK2	LIMK1	RHOC	RHOA	RAC1	MYL12B	RHOB	RND1	MYL6	ARHGAP35	ERBB2	MYH9	MYH14	MYH11	PLXNB1	MYH10	MYL9	MET	
REGULATION OF RAS BY GAPS%REACTOME DATABASE ID RELEASE 74%5658442	Regulation of RAS by GAPs	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	NRAS	PSMA8	PSMB6	HRAS	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	DAB2IP	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	KBTBD7	PSMC2	CUL3	RASAL1	RASAL2	RASAL3	NF1	RBX1	SPRED3	SYNGAP1	SPRED2	SPRED1	PSMD8	PSMD9	RASA3	PSMD6	PSMD7	RASA4	PSMD4	PSMD5	RASA1	PSMD2	PSMD3	RASA2	PSMD1	PSMA5	
NEF MEDIATED CD4 DOWN-REGULATION%REACTOME%R-HSA-167590.1	Nef Mediated CD4 Down-regulation	AP2A2	CD4	AP2M1	ARF1	ATP6V1H	LCK	AP2A1	AP2B1	AP2S1	
DRUG RESISTANCE OF PDGFR MUTANTS%REACTOME DATABASE ID RELEASE 74%9674415	Drug resistance of PDGFR mutants	PDGFRA	
LIPOPHAGY%REACTOME%R-HSA-9613354.3	Lipophagy	PLIN3	PRKAG3	PLIN2	PRKAB2	HSPA8	PRKAB1	PRKAA2	PRKAG1	PRKAG2	
NGF-STIMULATED TRANSCRIPTION%REACTOME%R-HSA-9031628.2	NGF-stimulated transcription	ASCL1	NAB1	FOS	CREB1	NAB2	FOSB	DNM2	CDK5R2	CDK5	ATF1	CHD4	TCF12	ATF2	REST	ELK1	SGK1	SRF	EGR2	SH3GL3	CDK5R1	ARC	TRIB1	TPH1	RRAD	F3	JUNB	EGR1	JUND	EGR3	EGR4	FOSL1	ID2	EP300	ID1	ID4	ID3	LYL1	MEF2D	VGF	
DNA DOUBLE STRAND BREAK RESPONSE%REACTOME%R-HSA-5693606.1	DNA Double Strand Break Response	BABAM1	HERC2	UIMC1	WHSC1	CHEK2	BAZ1B	RNF168	RNF8	BRCC3	APBB1	TP53BP1	ABL1	KDM4B	UBA52	EYA1	H2AFX	EYA2	EYA3	EYA4	BAP1	HIST2H2BE	BRE	FAM175A	HIST4H4	SMARCA5	PIAS4	UBE2N	HIST1H2BN	UBB	HIST1H2BM	HIST1H2BO	HIST1H2BJ	UBC	HIST1H2BI	BRCA1	HIST1H2BL	MAPK8	NBN	KPNA2	RPS27A	HIST1H2BK	HIST2H4A	HIST2H4B	KDM4A	MRE11A	HIST3H3	RAD50	SUMO1	UBE2I	BARD1	HIST3H2BB	MDC1	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	ATM	HIST1H2BD	HIST1H2BC	UBE2V2	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	PPP5C	HIST1H4E	HIST1H4F	TP53	
LIGAND-INDEPENDENT CASPASE ACTIVATION VIA DCC%REACTOME DATABASE ID RELEASE 74%418889	Ligand-independent caspase activation via DCC	UNC5A	UNC5B	MAGED1	DAPK1	DAPK2	DAPK3	APPL1	CASP9	CASP3	DCC	
REGULATION OF LIPID METABOLISM BY PPARALPHA%REACTOME DATABASE ID RELEASE 74%400206	Regulation of lipid metabolism by PPARalpha	ARNT	CYP1A1	AHRR	TGS1	NR1D1	ABCB4	PPARGC1A	MED19	MED16	MED15	MED18	MED17	CARM1	MED12	MED11	MED14	TBL1X	MED13	MED10	MED27	MED26	MED1	SIN3A	MED29	MED8	MED28	MED9	APOA1	MED23	MED4	MED22	MED25	MED24	MED21	MED6	MED20	PPARG	MED7	PPARA	CDK19	TBL1XR1	RORA	NFYA	NFYB	NFYC	MED30	MED31	NCOR2	NCOR1	THRAP3	FADS1	SULT2A1	CPT1A	ACSL1	CLOCK	PEX11A	NRF1	NPAS2	FDFT1	ALAS1	FAM120B	FHL2	GLIPR1	CPT2	ME1	ANKRD1	ESRRA	ACADM	HMGCS1	CYP4A11	MTF1	PLIN2	TNFRSF21	CYP7A1	ARNTL	UGT1A9	NR1H4	G0S2	GRHL1	AGT	FABP1	CCNC	SP1	CDK8	TXNRD1	APOA2	MED13L	APOA5	NCOA1	ANGPTL4	SLC27A1	NCOA2	NCOA6	NCOA3	SMARCD3	SREBF2	HDAC3	RXRA	ABCA1	NR1H2	NR1H3	RXRB	GPS2	TRIB3	HELZ2	AHR	HMGCS2	CHD9	CREBBP	EP300	TIAM2	PPARGC1B	CD36	ARNT2	RGL1	
CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE%REACTOME DATABASE ID RELEASE 74%442729	CREB1 phosphorylation through the activation of CaMKII CaMKK CaMKIV cascasde	KPNA2	CAMK4	CREB1	CAMK2G	CAMKK1	CAMKK2	CAMK2B	
STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES%REACTOME DATABASE ID RELEASE 74%1834941	STING mediated induction of host immune responses	STAT6	TBK1	IRF3	NLRP4	DTX4	MRE11A	TRIM21	TMEM173	PRKDC	XRCC6	XRCC5	TREX1	NLRC3	DDX41	IFI16	MB21D1	
GAP JUNCTION TRAFFICKING%REACTOME DATABASE ID RELEASE 74%190828	Gap junction trafficking	GJA1	DNM1	GJA3	DNM2	GJA5	GJA4	GJA9	GJA8	CLTB	GJC1	CLTCL1	GJC2	MYO6	GJB2	GJB1	GJB4	GJB3	GJB6	AP2M1	GJB5	GJB7	CLTC	GJA10	CLTA	DAB2	GJD2	GJD4	GJD3	
HCMV EARLY EVENTS%REACTOME DATABASE ID RELEASE 74%9609690	HCMV Early Events	DYNC1LI1	DYNLL1	DYNC1LI2	HIST2H2AC	CREB1	NUP62	NDC1	SEC13	NUP133	HIST2H2BE	DYNC1I2	HIST4H4	NUP50	NUP54	EZH2	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	TBL1X	SUZ12	HIST2H4A	HIST2H2AB	HIST2H4B	HIST1H2AG	DYNC1H1	HIST1H2AA	NUP43	HIST1H2AM	RAE1	HIST1H2AL	RANBP2	HIST1H2AI	HIST1H2AH	HIST1H2AK	NUP35	HIST2H2BF	HIST3H2A	NUPL2	NUP37	DYNLL2	TBL1XR1	DAXX	NCOR2	NCOR1	PML	DYNC1I1	EGFR	NFKB1	CBX1	TRIM28	NUP107	NUP188	HIST1H2AE	HIST1H2AD	HDAC3	HIST3H2BB	HIST1H2AC	HIST1H2AB	NUP214	NUP210	HIST1H2AJ	NUP93	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	ITGB1	HIST1H2BD	HIST1H2BC	NUP205	POM121	HIST1H3J	AAAS	ELK1	NUP160	GPS2	HIST1H3A	NUP85	RBBP4	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	HIST1H3I	RBBP7	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	NUP155	HIST1H4K	HIST1H4L	NUP153	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	EED	HIST2H2AA3	HIST2H2AA4	
SIALIC ACID METABOLISM%REACTOME DATABASE ID RELEASE 74%4085001	Sialic acid metabolism	GLB1	ST3GAL4	SLC35A1	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	ST6GALNAC1	CMAS	NANP	ST6GALNAC3	ST6GALNAC4	NANS	ST6GAL2	ST6GALNAC5	ST6GALNAC6	GNE	NPL	NEU2	NEU3	NEU4	NEU1	SLC17A5	ST8SIA4	ST8SIA5	ST3GAL5	ST3GAL6	ST8SIA6	CTSA	ST8SIA1	ST8SIA2	ST6GALNAC2	ST8SIA3	
CONSTITUTIVE SIGNALING BY NOTCH1 T(7;9)(NOTCH1:M1580_K2555) TRANSLOCATION MUTANT%REACTOME%R-HSA-2660826.1	Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	ADAM10	DLL1	DLL4	ADAM17	JAG2	JAG1	NOTCH1	
RNA POLYMERASE I TRANSCRIPTION%REACTOME%R-HSA-73864.3	RNA Polymerase I Transcription	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HDAC2	HDAC1	CBX3	MBD2	POLR2E	POLR2F	POLR2H	POLR2K	POLR2L	MAPK3	TBP	PTRF	POLR1C	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	RRN3	CCNH	EHMT2	H2AFB1	CHD4	HIST1H3J	CHD3	TTF1	TAF1D	ZNRD1	HIST1H3A	MTA1	RBBP4	TAF1B	HIST1H3F	TAF1C	HIST1H3G	TWISTNB	TAF1A	HIST1H3H	UBTF	HIST1H3I	RBBP7	HIST1H3B	MTA2	HIST1H3C	MTA3	HIST1H3D	MBD3	CD3EAP	HIST1H3E	GTF2H1	GTF2H2	H3F3B	GTF2H3	HIST1H4K	GTF2H4	HIST1H4L	GATAD2B	GTF2H5	GATAD2A	KAT2B	H3F3A	CDK7	KAT2A	H2BFS	ERCC3	HIST1H4A	POLR1A	HIST1H4B	POLR1B	HIST1H4H	ERCC2	HIST1H4I	POLR1E	HIST1H4J	ERCC6	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
SYNTHESIS OF PA%REACTOME%R-HSA-1483166.6	Synthesis of PA	PLA2G4D	PLA2G4B	PLA2G4A	GNPAT	GPD2	AGPAT5	PLA2G10	AGPAT6	GPD1	AGPAT9	PLA2G1B	AGPAT1	AGPAT2	PLA2R1	AGPAT3	AGPAT4	GPAT2	PLA2G2F	PLA2G5	PLD6	PLA2G2D	PLA2G2E	PLD1	PLD2	PLA2G2A	DDHD2	DDHD1	GPAM	LPCAT4	GPD1L	ALPI	LPCAT1	LCLAT1	LIPI	ACP6	LIPH	FAM73A	FAM73B	PLA2G12A	
TRANSLESION SYNTHESIS BY REV1%REACTOME%R-HSA-110312.1	Translesion synthesis by REV1	RPS27A	REV1	RFC5	MAD2L2	RFC3	REV3L	PCNA	RPA1	RFC4	RPA2	RFC1	UBA52	RFC2	RPA3	UBB	UBC	
TOLL LIKE RECEPTOR 7 8 (TLR7 8) CASCADE%REACTOME DATABASE ID RELEASE 74%168181	Toll Like Receptor 7 8 (TLR7 8) Cascade	RPS6KA1	RIPK2	MAPK3	IRAK4	FOS	CREB1	DUSP4	TRAF6	IRF7	PELI1	UBA52	TLR8	TLR7	UBE2V1	DUSP6	DUSP7	CUL1	RELA	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	TLR9	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	TICAM2	LY96	TICAM1	CD14	TLR4	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	AGER	BTRC	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
DISEASES OF GLYCOSYLATION%REACTOME%R-HSA-3781865.1	Diseases of glycosylation	PMM2	DOLK	B4GALT7	GLB1	CHST3	CHSY1	SLC26A2	GALNT12	MUCL1	MUC17	MUC5B	MUC3A	MUC5AC	MUC1	MUC7	MUC12	HEXB	MUC13	NCAN	MUC15	MUC20	HEXA	BGN	MUC4	MUC21	VCAN	MUC6	SDC4	CSPG5	CSPG4	B3GAT3	SDC3	GPC3	SDC1	GPC2	GPC5	GPC4	GPC6	B4GALT1	AGRN	DPM1	DPM2	DPM3	GALNT3	GALT	GALE	PGM1	GALK1	SEMA5A	HSPG2	BCAN	ADAMTS16	ADAMTS18	MGAT2	ST3GAL3	NOTCH1	MOGS	ADAMTS4	ADAMTS5	MAN1B1	ADAMTS1	ADAMTS2	GFPT1	ADAMTS3	SDC2	ADAMTS8	CHST6	ADAMTS9	ADAMTS14	DCN	LUM	DPAGT1	OGN	ALG8	OMD	ALG9	PRELP	ALG6	KERA	ALG14	FMOD	ALG3	ALG13	ALG12	ALG1	MPDU1	RFT1	NOTCH3	NOTCH4	GPC1	POMT2	SPON2	THBS1	SEMA5B	SPON1	THSD7B	POMT1	LFNG	ADAMTSL1	C1GALT1C1	DAG1	ADAMTSL4	MPI	ADAMTSL3	ADAMTSL2	THSD7A	ADAMTS6	ADAMTS7	ALG2	SBSPON	POMGNT1	ALG11	ADAMTS20	B3GLCT	THBS2	CFP	ADAMTS12	DHDDS	THSD1	ADAMTS10	THSD4	ADAMTS15	GNE	ADAMTS13	ADAMTS19	LARGE	ADAMTS17	C1GALT1	B4GAT1	NOTCH2	NEU1	CHST14	B3GALT6	EXT1	EXT2	CTSA	NUS1	PAPSS2	SRD5A3	
DEFECTIVE ABCC8 CAN CAUSE HYPO- AND HYPER-GLYCEMIAS%REACTOME%R-HSA-5683177.2	Defective ABCC8 can cause hypo- and hyper-glycemias	KCNJ11	ABCC8	
SYNAPTIC ADHESION-LIKE MOLECULES%REACTOME%R-HSA-8849932.4	Synaptic adhesion-like molecules	FLOT1	PTPRS	GRIN1	FLOT2	RTN3	PTPRF	DLG1	LRFN3	DLG3	PTPRD	DLG4	LRFN2	LRFN4	LRFN1	GRIA1	GRIN2B	GRIN2A	GRIN2D	GRIA3	GRIA4	GRIN2C	
METABOLISM OF INGESTED SEMET, SEC, MESEC INTO H2SE%REACTOME%R-HSA-2408508.2	Metabolism of ingested SeMet, Sec, MeSec into H2Se	NNMT	CBS	AHCY	GNMT	MAT1A	HNMT	CTH	SCLY	
UNWINDING OF DNA%REACTOME DATABASE ID RELEASE 74%176974	Unwinding of DNA	MCM3	MCM4	CDC45	GINS1	MCM7	MCM5	GINS2	MCM8	GINS3	MCM6	GINS4	MCM2	
SARS-COV INFECTIONS%REACTOME%R-HSA-9679506.2	SARS-CoV Infections	JAK3	ZBP1	JAK1	TBK1	CHMP2B	CHMP2A	CHMP4C	PHF21A	CHMP4B	VCP	UBA52	CHMP3	CHMP4A	TLR7	CHMP6	CHMP7	UBB	MAN2A1	UBC	TLR9	RPS27A	HMG20B	HDAC2	JAK2	HDAC1	MAP1LC3B	ROCK1	ACE2	ROCK2	TMPRSS2	ZCRB1	FKBP1A	DDX5	HSP90AB1	GSK3A	PIK3C3	GALNT1	ST6GALNAC2	RPN2	PRKCSH	TUSC3	RPN1	MAGT1	GANAB	FUT8	MGAT5	ST3GAL4	MGAT1	MGAT2	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	EDEM2	MOGS	DDOST	MGAT4C	DAD1	MGAT4A	MGAT4B	STT3A	MAN1B1	ST6GALNAC3	CTSL	ST6GALNAC4	AP2A1	AP2A2	AP2M1	CANX	RB1	SUMO1	UBE2I	FURIN	VHL	AP2S1	FKBP4	ARID4A	ARID4B	COMT	NR3C1	ITGA4	CYSLTR1	IL1R1	RIPK1	SIGMAR1	ATP1B3	ATP1B2	TYK2	ATP1B1	AP2B1	SAP30	BRMS1	IFNAR1	IFNGR1	IFNGR2	ATP1A4	ATP1A3	ITGB1	ATP1A2	PTGES3	IL6R	ATP1A1	UVRAG	SAP30L	PARP16	S1PR1	PARP14	SAP18	SUDS3	PARP10	CHD4	PARP6	BRD4	CHD3	PARP4	CRBN	PARP9	STAT2	PARP8	REST	FXYD4	BECN1	FXYD3	MTA1	RBBP4	IMPDH1	IMPDH2	FXYD2	FXYD1	FXYD7	FXYD6	RBBP7	PDCD1	MTA2	MTA3	MBD3	GSK3B	GATAD2B	PIK3R4	GATAD2A	KDM1A	HSP90AA1	TUBB	
NICOTINAMIDE SALVAGING%REACTOME%R-HSA-197264.5	Nicotinamide salvaging	NNMT	PTGS2	SLC5A8	CARKD	RNLS	PTGIS	APOA1BP	SLC22A13	NAPRT	NAMPT	NUDT12	PARP16	PARP14	PARP10	PARP6	PARP4	CYP8B1	PARP9	PARP8	
TICAM1 DEFICIENCY - HSE%REACTOME DATABASE ID RELEASE 74%5602566	TICAM1 deficiency - HSE	TLR3	TICAM1	
ROLE OF ABL IN ROBO-SLIT SIGNALING%REACTOME%R-HSA-428890.2	Role of ABL in ROBO-SLIT signaling	CLASP1	CAP1	ROBO1	ABL2	CAP2	CLASP2	ABL1	SLIT2	
DEFECTIVE SLC17A5 CAUSES SALLA DISEASE (SD) AND ISSD%REACTOME DATABASE ID RELEASE 74%5619035	Defective SLC17A5 causes Salla disease (SD) and ISSD	SLC17A5	
INTERCONVERSION OF NUCLEOTIDE DI- AND TRIPHOSPHATES%REACTOME%R-HSA-499943.6	Interconversion of nucleotide di- and triphosphates	DTYMK	AK1	AK2	GLRX	AK4	AK5	TYMS	AK7	AK8	AK9	GUK1	NUDT13	RRM1	NME2	CTPS2	RRM2B	NME3	CTPS1	NME4	NME1	DCTD	CMPK1	DCTPP1	TXNRD1	TXN	RRM2	TAF9	AK6	
INTERLEUKIN-7 SIGNALING%REACTOME DATABASE ID RELEASE 74%1266695	Interleukin-7 signaling	IL2RG	IRS1	JAK3	JAK1	HIST2H3A	HIST2H3D	HIST2H3C	PIK3R3	PIK3R2	PIK3R1	HIST1H3J	HIST1H3A	RAG2	RAG1	HIST1H3F	TSLP	HIST1H3G	IL7	BRWD1	HIST1H3H	CRLF2	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	STAT5A	STAT5B	SMARCA4	SOCS1	IRS2	STAT3	CISH	SOCS2	IL7R	HGF	
ACTIVATION OF AMPK DOWNSTREAM OF NMDARS%REACTOME%R-HSA-9619483.1	Activation of AMPK downstream of NMDARs	PRKAG3	PRKAB2	CAMKK2	PRKAA1	PRKAB1	PRKAA2	PRKAG1	PRKAG2	
SIGNALING BY NTRK2 (TRKB)%REACTOME DATABASE ID RELEASE 74%9006115	Signaling by NTRK2 (TRKB)	TIAM1	BDNF	SRC	PTPN11	NTF4	NTF3	FRS2	FRS3	RAC1	CDK5R1	GAB1	NRAS	CDK5	PLCG1	SOS1	HRAS	PIK3R1	GRIN2B	PIK3CA	NTRK2	DOCK3	
SIGNALING BY NON-RECEPTOR TYROSINE KINASES%REACTOME%R-HSA-9006927.3	Signaling by Non-Receptor Tyrosine Kinases	CDKN1B	UBA52	PELP1	EGF	CCNE1	CBL	EGFR	NRAS	HRAS	UBB	UBC	EPAS1	HBEGF	RPS27A	CDK2	RAC1	SFPQ	KHDRBS1	KHDRBS2	SRMS	KHDRBS3	PTK6	STAP2	ARHGAP35	DOCK1	ELMO1	ELMO2	NR3C1	RHOA	SOCS3	ERBB2	PTPN1	DOK1	CRK	BCAR1	PXN	AKT1	CCND1	ARAP1	EREG	GPNMB	CDK4	LRRK2	BTC	STAT3	NRG1	NRG2	NRG3	NRG4	RASA1	HIF1A	
SIGNALING BY ERBB2 TMD JMD MUTANTS%REACTOME DATABASE ID RELEASE 74%9665686	Signaling by ERBB2 TMD JMD mutants	ERBB2IP	EREG	SHC1	BTC	EGF	NRG1	ERBB2	EGFR	NRG2	NRAS	HSP90AA1	CDC37	NRG3	PLCG1	SOS1	NRG4	HRAS	HBEGF	
TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 74%190872	Transport of connexons to the plasma membrane	GJB2	GJA1	
FORMATION OF ATP BY CHEMIOSMOTIC COUPLING%REACTOME DATABASE ID RELEASE 74%163210	Formation of ATP by chemiosmotic coupling	ATP5F1	MT-ATP8	ATP5J2	ATP5S	ATP5A1	ATP5C1	ATP5J	ATP5I	ATP5H	ATP5G3	ATP5G2	ATP5O	ATP5G1	ATP5L	MT-ATP6	ATP5B	ATP5E	ATP5D	
SIGNALING BY NOTCH%REACTOME%R-HSA-157118.5	Signaling by NOTCH	HIST2H2AC	H2AFJ	DTX4	UBA52	H2AFZ	H2AFX	H2AFV	HIST2H2BE	SEL1L	HEY1	HIST4H4	PBX1	HEY2	CUL1	UBB	HIST1H2BN	HIST1H2BM	HIST1H2BO	UBC	RAB6A	HIST1H2BJ	HIST1H2BI	HIST1H2BL	RPS27A	TBL1X	HIST1H2BK	HIST2H4A	HIST2H4B	TMED2	B4GALT1	ATP2A3	ATP2A2	ATP2A1	TBL1XR1	WWC1	YBX1	PSMD8	DLGAP5	PTCRA	PSMD9	HEYL	PSMD6	FABP7	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	HIF1A	PSMD1	E2F1	PSMA5	PSMA6	PSMA3	PSMA4	CCNC	PSMA1	PSMA2	PSME3	PSME1	PSME2	ST3GAL4	PSMD10	PSMD12	ST3GAL3	PSMD11	PSMD14	NOTCH1	PSMD13	PSMB10	PSMA7	PSMB6	PSMB7	PSMB4	PSMB5	YWHAZ	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	SNW1	SIRT6	ELF3	NOTCH3	NOTCH4	E2F3	HDAC6	SMAD3	DNER	TLE4	TLE2	TLE1	DTX1	AKT1	RBX1	DTX2	DLK1	CCND1	NOTCH2	MAML2	MAML1	WWP2	PSEN2	RBPJ	DLL1	ST3GAL6	DLL4	APH1A	NEURL1B	APH1B	CREBBP	MDK	EP300	HES1	NUMB	HES5	JAG2	PSENEN	TP53	JAG1	TACC3	MIB2	GZMB	MIB1	FCER2	CREB1	NEURL1	CNTN1	MAML3	ITCH	MAMLD1	TNRC6C	MOV10	AGO3	AGO4	AGO1	AGO2	TNRC6A	TNRC6B	NBEA	MYC	HDAC2	RFNG	HDAC1	POGLUT1	POFUT1	MFNG	ACTA2	NCOR2	NCOR1	ARRB1	ARRB2	STAT1	PLXND1	ADAM10	ADAM17	PSEN1	NCSTN	HDAC4	HDAC5	HDAC8	EGF	HDAC9	CDK8	HDAC7	EGFR	HDAC10	HDAC11	FLT4	TFDP1	TFDP2	HIST1H2AE	HIST1H2AD	HDAC3	FURIN	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	LFNG	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	RUNX1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	JUN	KAT2B	SKP1	H3F3A	KAT2A	H2BFS	HIST1H4A	HIST1H4B	PRKCI	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
PTEN LOSS OF FUNCTION IN CANCER%REACTOME DATABASE ID RELEASE 74%5674404	PTEN Loss of Function in Cancer	PTEN	
GAMMA CARBOXYLATION, HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION%REACTOME%R-HSA-163841.4	Gamma carboxylation, hypusine formation and arylsulfatase activation	STS	DPH1	DPH2	EIF5A	EIF5A2	ARSJ	BGLAP	DPH3	DHPS	PROZ	ARSK	DOHH	ARSH	GAS6	ARSI	DPH5	PROS1	ARSF	DPH6	ARSG	DPH7	ARSD	ARSE	FN3K	ARSA	FN3KRP	SUMF2	SUMF1	TPST2	F10	TPST1	GGCX	EEF2	ARSB	F2	F7	ICMT	F8	F9	PROC	FURIN	
GENERATION OF SECOND MESSENGER MOLECULES%REACTOME DATABASE ID RELEASE 74%202433	Generation of second messenger molecules	PAK3	HLA-DQA1	TRAV19	PAK2	HLA-DRB5	HLA-DRB4	CD4	HLA-DPB1	HLA-DRA	HLA-DRB3	HLA-DRB1	PLCG1	LCK	GRAP2	LCP2	CD3G	FYB	ZAP70	LAT	CD101	CD3E	PLCG2	CD3D	NCK1	VASP	EVL	HLA-DPA1	ITK	HLA-DQB2	HLA-DQB1	PAK1	ENAH	WAS	HLA-DQA2	
PHASE I - FUNCTIONALIZATION OF COMPOUNDS%REACTOME%R-HSA-211945.5	Phase I - Functionalization of compounds	ARNT	ALDH1A1	CYP2C9	CYP2A7	CYP2A6	CYP2C8	CYP2W1	CYP2S1	CYP1A2	CYP1A1	AHRR	CYP2E1	CYP11A1	CYP7B1	MAOA	CYP4V2	TBXAS1	CYP4F12	CYB5R3	CYP4A22	PTGIS	HSP90AB1	CYP4F22	PTGS1	CYP4A11	FDX1	FDXR	FDX1L	CYP7A1	CYP4F2	CYP4F3	NR1H4	CYP4B1	CYP4F11	CYP4F8	CYP8B1	CYP1B1	ALDH2	CYP46A1	AIP	CMBL	CYP2U1	CYP39A1	CYP27A1	ALDH3A1	POR	CES2	CES1	MAOB	ADH7	CYP19A1	ADH5	ADH6	CYP27B1	MARC2	MARC1	EPHX1	CYP11B2	CYP11B1	CYP2R1	CYP21A2	ACSS2	ADH1B	BPHL	ALDH1B1	ACSS1	CBR3	CYB5B	NCOA1	AOC3	NQO2	CES3	NCOA2	AOC1	AOC2	FMO1	FMO2	FMO3	AADAC	RXRA	CYP51A1	PTGES3	POMC	CYP24A1	AHR	CYP2C19	CYP3A4	CYP2C18	ADH1C	ADH1A	CYP3A5	CYP3A7	CYP2B6	CYP2A13	CYP2D6	CYP26A1	ADH4	CYP2F1	CYP2J2	PAOX	CYP26B1	ARNT2	CYP3A7-CYP3A51P	CYP26C1	CYP3A43	
SUMOYLATION OF RNA BINDING PROTEINS%REACTOME DATABASE ID RELEASE 74%4570464	SUMOylation of RNA binding proteins	NUP214	NUP210	PHC2	PHC1	NUP62	NUP93	NDC1	SEC13	NUP133	PHC3	BMI1	NUP50	NUP205	SUMO2	NUP54	POM121	NOP58	AAAS	RING1	NUP160	NUP85	TPR	NUP88	NUP43	RAE1	RANBP2	PCGF2	NUP155	NUP35	RNF2	NUPL2	NUP37	HNRNPK	NUP107	SUMO1	NUP153	NUP188	UBE2I	HNRNPC	CBX8	CBX4	CBX2	
TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 74%83936	Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	ARL2	SLC25A5	SLC29A4	SLC25A4	SLC25A6	SLC29A1	SLC28A2	SLC28A1	SLC29A3	SLC28A3	SLC29A2	ARL2BP	
SYNTHESIS, SECRETION, AND DEACYLATION OF GHRELIN%REACTOME%R-HSA-422085.2	Synthesis, secretion, and deacylation of Ghrelin	GH1	SPCS3	CRHR2	SPCS2	SPCS1	GCG	SEC11A	INS	SEC11C	KLF4	UCN	LEP	IGF1	ACHE	BCHE	MBOAT4	PCSK1	PLA2G7	
THE PROTON BUFFERING MODEL%REACTOME%R-HSA-167827.2	The proton buffering model	SLC25A27	UCP3	UCP2	UCP1	SLC25A14	
ESSENTIAL FRUCTOSURIA%REACTOME%R-HSA-5657562.3	Essential fructosuria	KHK	
UBIQUITIN MEDIATED DEGRADATION OF PHOSPHORYLATED CDC25A%REACTOME DATABASE ID RELEASE 74%69601	Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	CHEK2	PSME3	CHEK1	PSME4	PSME1	CDC25A	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
DEFECTIVE SLC16A1 CAUSES SYMPTOMATIC DEFICIENCY IN LACTATE TRANSPORT (SDLT)%REACTOME%R-HSA-5619070.1	Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)	SLC16A1	BSG	
SIGNALING BY INSULIN RECEPTOR%REACTOME DATABASE ID RELEASE 74%74752	Signaling by Insulin receptor	ATP6V0C	ATP6V1B1	MAPK3	ATP6V1A	PTPN11	ATP6V0A2	ATP6V1H	ATP6V0A4	GAB2	ATP6V1G3	SHC1	ATP6V0E2	ATP6V1D	GAB1	ATP6V1C1	ATP6V1C2	NRAS	ATP6V0A1	ATP6V1F	SOS1	HRAS	TLR9	INSR	MAPK1	KLB	IRS2	FGF1	PIK3CB	FGF2	FGF3	FGF4	FGF6	FGF7	FGF9	IRS1	INS	FGF20	FGF23	FGF22	FGF16	PDPK1	FGF19	PIK3R2	FGF18	PIK3R1	FGFR4	PIK3CA	AKT2	FGF10	FLT3	PDE3B	THEM4	TRIB3	FLT3LG	FRS2	TCIRG1	PIK3R4	ATP6V1E1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	GRB10	ATP6V1G2	ATP6AP1	PIK3C3	ATP6V1B2	ATP6V0D1	ATP6V0D2	
INTERLEUKIN-21 SIGNALING%REACTOME%R-HSA-9020958.2	Interleukin-21 signaling	IL21R	IL2RG	STAT4	JAK3	JAK1	STAT5A	STAT5B	STAT1	IL21	STAT3	
INHIBITION OF IFN-BETA%REACTOME%R-HSA-168888.4	Inhibition of IFN-beta	
DEFECTIVE SLC5A7 CAUSES DISTAL HEREDITARY MOTOR NEURONOPATHY 7A (HMN7A)%REACTOME%R-HSA-5619114.1	Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)	SLC5A7	
TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS%REACTOME%R-HSA-6803211.1	TP53 Regulates Transcription of Death Receptors and Ligands	TP53BP2	TNFRSF10D	TNFRSF10C	TNFRSF10B	TMEM219	IGFBP3	TNFRSF10A	PPP1R13B	TP73	FAS	TP63	TP53	
SHC-RELATED EVENTS TRIGGERED BY IGF1R%REACTOME%R-HSA-2428933.1	SHC-related events triggered by IGF1R	NRAS	IGF1R	SOS1	HRAS	IGF2	IGF1	
CASP8 ACTIVITY IS INHIBITED%REACTOME%R-HSA-5218900.2	CASP8 activity is inhibited	TNFRSF10B	TRAF2	TNFRSF10A	FASLG	CASP8	TNFSF10	FAS	RIPK1	FADD	TRADD	
PHOSPHORYLATION OF THE APC C%REACTOME DATABASE ID RELEASE 74%176412	Phosphorylation of the APC C	UBE2C	UBE2D1	CDC23	UBE2S	CDC26	PLK1	CDC16	CDC27	ANAPC7	UBE2E1	CDK1	ANAPC4	ANAPC5	CCNB1	ANAPC1	ANAPC2	ANAPC15	ANAPC16	ANAPC10	ANAPC11	
HISTAMINE RECEPTORS%REACTOME%R-HSA-390650.2	Histamine receptors	HRH3	HRH2	HRH4	HRH1	
ACYL CHAIN REMODELLING OF PE%REACTOME DATABASE ID RELEASE 74%1482839	Acyl chain remodelling of PE	PLA2G4D	PLA2G4B	PLA2G4C	HRASLS2	PLA2G4A	PLA2G16	PLA2G10	PLA2G1B	PLBD1	HRASLS5	PLA2R1	ABHD4	PLA2G3	PLA2G2F	PLA2G5	PLA2G2D	PLA2G6	PLA2G2E	PNPLA8	PLA2G2A	MBOAT1	MBOAT2	LPCAT4	RARRES3	LPCAT3	PLA2G12A	PLA2G4F	
IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX%REACTOME DATABASE ID RELEASE 74%937042	IRAK2 mediated activation of TAK1 complex	RPS27A	UBB	TAB3	TAB2	TAB1	TRAF6	UBC	UBA52	MAP3K7	IRAK2	
DEFECTIVE ABCG8 CAUSES GBD4 AND SITOSTEROLEMIA%REACTOME%R-HSA-5679090.2	Defective ABCG8 causes GBD4 and sitosterolemia	ABCG8	ABCG5	
PI5P REGULATES TP53 ACETYLATION%REACTOME%R-HSA-6811555.2	PI5P Regulates TP53 Acetylation	MAP2K6	TMEM55B	PIN1	PIP4K2A	PIP4K2B	PIP4K2C	EP300	ING2	TP53	
TYPE II NA+ PI COTRANSPORTERS%REACTOME DATABASE ID RELEASE 74%427589	Type II Na+ Pi cotransporters	SLC34A1	SLC34A2	SLC34A3	
BETA OXIDATION OF PALMITOYL-COA TO MYRISTOYL-COA%REACTOME DATABASE ID RELEASE 74%77305	Beta oxidation of palmitoyl-CoA to myristoyl-CoA	HADHB	HADHA	ACADVL	
PHENYLALANINE METABOLISM%REACTOME DATABASE ID RELEASE 74%8964208	Phenylalanine metabolism	PAH	PCBD1	ASRGL1	CCBL1	QDPR	IL4I1	
RUNX3 REGULATES CDKN1A TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%8941855	RUNX3 regulates CDKN1A transcription	SMAD3	ZFHX3	CDKN1A	TGFB1	RUNX3	SMAD4	TP53	
ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS%REACTOME%R-HSA-9659787.1	Aberrant regulation of mitotic G1 S transition in cancer due to RB1 defects	CDKN1A	CCND2	CDKN1B	E2F3	CDK6	CDK2	CCND1	CDK4	CCND3	CCNE2	CCNE1	RB1	CDKN1C	TFDP1	TFDP2	E2F2	E2F1	
RHESUS GLYCOPROTEINS MEDIATE AMMONIUM TRANSPORT.%REACTOME%R-HSA-444411.1	Rhesus glycoproteins mediate ammonium transport.	RHAG	RHCG	RHBG	
OPIOID SIGNALLING%REACTOME DATABASE ID RELEASE 74%111885	Opioid Signalling	ADCY2	ADCY1	ADCY8	ADCY7	CREB1	ADCY6	CAMK2G	PLA2G4A	ADCY5	GNG12	GNG11	GNG13	GNAO1	GNB2	GNAT1	PRKCG	GNB1	PLCB4	PDE1C	GNB4	PDE1B	GNB3	PDE1A	GNAL	CDK5	ADRBK1	GNB5	PRKCD	CAMKK1	CAMKK2	PRKAR2B	GNAT3	KPNA2	NBEA	CAMK4	PPP2CA	PPP2CB	MAPK1	AHCYL1	PRKX	PDYN	PPP2R1B	GNAI3	GNAI1	GNAI2	PRKCA	OPRM1	GNAZ	PPP1CA	PRKACG	PRKACB	GNGT1	PPP3CC	PDE4B	PPP3CA	PDE4A	PPP3CB	PDE4D	GNGT2	PDE4C	POMC	GNAT2	ADCY9	PPP1R1B	PRKAR1B	PPP2R1A	PRKAR1A	PLCB3	PLCB1	PLCB2	PRKACA	CAMK2A	PRKAR2A	ITPR1	PPP2R5D	ITPR2	ITPR3	GNG3	GNG10	PPP3R1	GNG2	GNG5	GNG4	GNG7	GNG8	CAMK2B	ADCY4	CAMK2D	ADCY3	
DEFECTIVE CYP11B1 CAUSES ADRENAL HYPERPLASIA 4 (AH4)%REACTOME DATABASE ID RELEASE 74%5579017	Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4)	CYP11B1	
REELIN SIGNALLING PATHWAY%REACTOME DATABASE ID RELEASE 74%8866376	Reelin signalling pathway	SH3KBP1	RELN	DAB1	FYN	VLDLR	
RUNX3 REGULATES NOTCH SIGNALING%REACTOME DATABASE ID RELEASE 74%8941856	RUNX3 regulates NOTCH signaling	RUNX3	MAML3	MAMLD1	SNW1	NOTCH1	MAML2	MAML1	KAT2B	RBPJ	KAT2A	CREBBP	EP300	HES1	JAG1	
NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS%REACTOME DATABASE ID RELEASE 74%9013507	NOTCH3 Activation and Transmission of Signal to the Nucleus	MIB2	NOTCH3	MIB1	NCSTN	NEURL1	UBA52	EGF	EGFR	UBB	UBC	RPS27A	YBX1	PSEN2	WWP2	ADAM10	DLL1	DLL4	APH1A	NEURL1B	APH1B	JAG2	PSEN1	PSENEN	JAG1	TACC3	
TYSND1 CLEAVES PEROXISOMAL PROTEINS%REACTOME DATABASE ID RELEASE 74%9033500	TYSND1 cleaves peroxisomal proteins	HSD17B4	ACOX1	ACAA1	SCP2	AGPS	PHYH	TYSND1	
HH MUTANTS ABROGATE LIGAND SECRETION%REACTOME%R-HSA-5387390.3	Hh mutants abrogate ligand secretion	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	HHAT	PSME1	PSME2	PSMD10	PSMB11	VCP	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	SEL1L	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	SYVN1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	DERL2	ERLEC1	OS9	IHH	SHH	DHH	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
ORGANIC CATION ANION ZWITTERION TRANSPORT%REACTOME%R-HSA-549132.1	Organic cation anion zwitterion transport	SLC22A2	SLC22A5	SLC22A1	SLC22A18	SLC22A4	SLC22A3	SLC22A6	SLC22A15	SLC22A16	SLC22A12	SLC22A8	SLC22A7	SLC22A11	RSC1A1	RUNX1	
CARNITINE SYNTHESIS%REACTOME%R-HSA-71262.2	Carnitine synthesis	SHMT1	BBOX1	TMLHE	ALDH9A1	
INVADOPODIA FORMATION%REACTOME DATABASE ID RELEASE 74%8941237	Invadopodia formation	ADAM15	ADAM19	SH3PXD2A	ADAM12	
BUDDING%REACTOME DATABASE ID RELEASE 74%168302	Budding	
KERATAN SULFATE KERATIN METABOLISM%REACTOME DATABASE ID RELEASE 74%1638074	Keratan sulfate keratin metabolism	B3GNT4	B3GNT3	SLC35D2	B3GNT2	CHST1	GLB1	B4GALT6	CHST5	B4GALT4	B4GALT5	CHST2	ST3GAL4	ST3GAL1	ST3GAL2	ST3GAL3	CHST6	HEXB	HEXA	B4GAT1	GLB1L	LUM	OGN	OMD	PRELP	ST3GAL6	KERA	FMOD	B4GALT2	B4GALT1	GNS	B4GALT3	B3GNT7	
FMO OXIDISES NUCLEOPHILES%REACTOME%R-HSA-217271.1	FMO oxidises nucleophiles	FMO1	FMO2	FMO3	
ACTIVATED NTRK3 SIGNALS THROUGH PI3K%REACTOME%R-HSA-9603381.1	Activated NTRK3 signals through PI3K	IRS1	SRC	NTRK3	NTF3	PIK3R1	PIK3CA	
MINERALOCORTICOID BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%193993	Mineralocorticoid biosynthesis	LHB	CGA	CYP11B2	CYP21A2	HSD3B2	HSD3B1	
PRESYNAPTIC PHASE OF HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE%REACTOME%R-HSA-5693616.1	Presynaptic phase of homologous DNA pairing and strand exchange	RAD17	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	CHEK1	KAT5	ATM	BRCA1	XRCC2	BRCA2	NBN	TOP3A	RAD51D	BLM	RFC5	RFC3	RBBP8	RPA1	RFC4	RPA2	MRE11A	RFC2	RAD51B	RAD50	RAD51C	RAD51	RPA3	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	WRN	RMI1	HUS1	
ACTIVATION OF NIMA KINASES NEK9, NEK6, NEK7%REACTOME%R-HSA-2980767.2	Activation of NIMA Kinases NEK9, NEK6, NEK7	NEK7	CCNB2	CCNB1	NEK9	PLK1	NEK6	CDK1	
LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS%REACTOME DATABASE ID RELEASE 74%8876384	Listeria monocytogenes entry into host cells	SH3KBP1	RPS27A	CBLL1	STAM	SRC	CDH1	HGS	EPS15	UBA52	SH3GL1	SH3GL3	STAM2	CBL	CTNND1	CTNNB1	SH3GL2	UBB	UBC	MET	
TBC RABGAPS%REACTOME DATABASE ID RELEASE 74%8854214	TBC RABGAPs	GGA2	TBC1D2	RABEP1	GGA1	MAP1LC3B	TBC1D3	GGA3	RABGEF1	RAB8B	TBC1D7	RAB33A	RAB33B	RAB7B	GABARAPL2	RABGAP1	OPTN	SYTL1	RAB11B	RAB35	RAB5B	RAB5C	GABARAP	TSC2	RAB5A	TSC1	RAB6A	RAB6B	RAB4A	TBC1D10C	TBC1D10A	TBC1D20	TBC1D10B	TBC1D24	TBC1D25	ULK1	TBC1D13	TBC1D14	TBC1D17	RAB11A	TBC1D15	TBC1D16	RAB7A	RAB8A	ARF6	
GSD IA%REACTOME%R-HSA-3274531.2	GSD Ia	G6PC	
LDL REMODELING%REACTOME DATABASE ID RELEASE 74%8964041	LDL remodeling	APOF	APOB	LPA	CETP	
CYTOCHROME P450 - ARRANGED BY SUBSTRATE TYPE%REACTOME%R-HSA-211897.2	Cytochrome P450 - arranged by substrate type	ARNT	CYP2C9	CYP1B1	CYP2A7	CYP2A6	CYP2C8	CYP2W1	CYP2S1	CYP1A2	CYP1A1	AHRR	CYP2E1	CYP46A1	CYP2U1	CYP39A1	CYP27A1	POR	CYP11A1	CYP19A1	CYP27B1	CYP11B2	CYP11B1	CYP2R1	CYP21A2	CYP7B1	NCOA1	NCOA2	CYP4V2	RXRA	TBXAS1	CYP51A1	CYP4F12	CYP4A22	POMC	PTGIS	CYP4F22	CYP24A1	CYP4A11	FDX1	FDXR	AHR	FDX1L	CYP2C19	CYP7A1	CYP3A4	CYP4F2	CYP2C18	CYP4F3	CYP3A5	NR1H4	CYP3A7	CYP4B1	CYP2B6	CYP4F11	CYP2A13	CYP4F8	CYP2D6	CYP8B1	CYP26A1	CYP2F1	CYP2J2	CYP26B1	ARNT2	CYP3A7-CYP3A51P	CYP26C1	CYP3A43	
NEUROTRANSMITTER UPTAKE AND METABOLISM IN GLIAL CELLS%REACTOME DATABASE ID RELEASE 74%112313	Neurotransmitter uptake and metabolism In glial cells	GLUL	SLC1A3	SLC38A1	SLC1A2	
G2 M CHECKPOINTS%REACTOME DATABASE ID RELEASE 74%69481	G2 M Checkpoints	MCM7	MCM8	CDC7	UBA52	H2AFX	HIST2H2BE	HIST4H4	MCM3	MCM4	MCM5	CCNB2	CCNB1	MCM6	UBB	CLSPN	HIST1H2BN	MCM2	HIST1H2BM	HIST1H2BO	UBC	HIST1H2BJ	HIST1H2BI	BRCA1	HIST1H2BL	ORC5	NBN	ORC4	RPS27A	TOP3A	HIST1H2BK	ORC6	ORC1	HIST2H4A	ORC3	ORC2	HIST2H4B	BLM	CDC6	RBBP8	RPA1	RPA2	CDK2	MRE11A	HIST3H3	CDK1	RAD50	RPA3	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	MDC1	RAD17	WEE1	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	ATM	MCM10	UBE2V2	DBF4	YWHAQ	SFN	YWHAH	RFC5	RFC3	RFC4	RFC2	PSMD8	PSMD9	CDC45	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	BABAM1	PSMA3	HERC2	PSMA4	UIMC1	PSMA1	WHSC1	PSMA2	CHEK2	PSME3	CHEK1	PSME4	RNF168	PSME1	RNF8	CDC25A	PSME2	BRCC3	PSMD10	TP53BP1	PSMB11	PSMD12	PSMD11	PSMD14	CDC25C	PSMD13	BRE	FAM175A	YWHAB	PSMB10	PSMA7	PSMA8	PSMB6	PIAS4	UBE2N	PSMB7	PSMB4	YWHAZ	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	GTSE1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	SUMO1	HIST3H2BB	PKMYT1	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	YWHAE	HIST1H4K	HIST1H4L	YWHAG	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	TP53	
RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE%REACTOME DATABASE ID RELEASE 74%110330	Recognition and association of DNA glycosylase with site containing an affected purine	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST3H3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	MPG	HIST1H2AJ	OGG1	TINF2	TERF1	TERF2	NEIL3	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
REGULATION OF THE APOPTOSOME ACTIVITY%REACTOME DATABASE ID RELEASE 74%9627069	Regulation of the apoptosome activity	MAPK3	AVEN	APAF1	DIABLO	CARD8	MAPK1	APIP	XIAP	UACA	CASP9	CYCS	
DSCAM INTERACTIONS%REACTOME%R-HSA-376172.1	DSCAM interactions	DSCAML1	MAPK12	DSCAM	DCC	NTN1	RAC1	MAPK14	MAPK13	MAPK11	PAK1	MAPK8	
MULTIFUNCTIONAL ANION EXCHANGERS%REACTOME%R-HSA-427601.2	Multifunctional anion exchangers	SLC26A6	SLC5A12	SLC26A2	SLC26A1	SLC26A11	SLC26A7	SLC26A9	SLC26A4	SLC26A3	
STIMULATION OF THE CELL DEATH RESPONSE BY PAK-2P34%REACTOME%R-HSA-211736.1	Stimulation of the cell death response by PAK-2p34	PAK2	CASP3	
GRB2:SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS%REACTOME DATABASE ID RELEASE 74%354194	GRB2:SOS provides linkage to MAPK signaling for Integrins	SRC	FGB	FGA	RAP1B	VWF	ITGA2B	RAP1A	FGG	TLN1	FN1	SOS1	APBB1IP	PTK2	ITGB3	
SIGNALING BY KINASE DOMAIN MUTANTS OF KIT%REACTOME%R-HSA-9669933.1	Signaling by kinase domain mutants of KIT	KIT	
VEGF LIGAND-RECEPTOR INTERACTIONS%REACTOME DATABASE ID RELEASE 74%194313	VEGF ligand-receptor interactions	FIGF	FLT1	FLT4	VEGFB	KDR	VEGFC	PGF	VEGFA	
TOXICITY OF BOTULINUM TOXIN TYPE B (BONT B)%REACTOME DATABASE ID RELEASE 74%5250958	Toxicity of botulinum toxin type B (BoNT B)	SYT2	VAMP2	SYT1	
SDK INTERACTIONS%REACTOME DATABASE ID RELEASE 74%373756	SDK interactions	SDK1	SDK2	
SIGNALING BY SCF-KIT%REACTOME%R-HSA-1433557.4	Signaling by SCF-KIT	CMA1	PRKCA	PTPRU	CHEK1	PTPN11	SOCS6	FER	GRAP	GAB2	GRB7	CBL	PTPN6	NRAS	FES	LYN	SOS1	PIK3R3	HRAS	PIK3R2	PIK3R1	PIK3CA	LCK	KIT	GRAP2	FYN	STAT5A	STAT5B	MMP9	SOCS1	RAC1	YES1	STAT1	STAT3	VAV1	JAK2	GRB10	SH2B3	TEC	
METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS%REACTOME%R-HSA-2022377.5	Metabolism of Angiotensinogen to Angiotensins	CMA1	CTSD	ACE2	CPA3	ENPEP	ACE	CPB1	MME	ATP6AP2	AGT	C9orf3	CTSZ	GZMH	ANPEP	CPB2	REN	CTSG	CES1	
CELL CYCLE CHECKPOINTS%REACTOME%R-HSA-69620.2	Cell Cycle Checkpoints	DYNC1LI1	DYNLL1	DYNC1LI2	CKAP5	MCM7	ZW10	MCM8	UBE2D1	CDC23	CDC26	MAPRE1	CDC27	SEC13	NUP133	UBA52	ANAPC7	UBE2E1	H2AFX	PAFAH1B1	CCNA2	CCNA1	HIST2H2BE	DYNC1I2	CCNE2	CCNE1	HIST4H4	MCM3	MCM4	ANAPC4	MCM5	ANAPC5	CCNB2	CCNB1	MCM6	ANAPC1	UBB	HIST1H2BN	MCM2	HIST1H2BM	ANAPC2	ANAPC15	HIST1H2BO	ANAPC16	UBC	HIST1H2BJ	ANAPC10	HIST1H2BI	ANAPC11	BRCA1	HIST1H2BL	ORC5	RPS27A	NBN	ORC4	TOP3A	HIST1H2BK	PPP2CA	ORC6	KIF18A	HIST2H4A	ORC1	CLASP1	PPP2CB	ORC3	HIST2H4B	ORC2	DYNC1H1	BLM	UBE2C	NUP43	CDC6	RBBP8	RANBP2	NDE1	RPA1	UBE2S	PLK1	CDC16	RPA2	MRE11A	CDK2	HIST3H3	CLIP1	CDK1	RAD50	NUP37	RPA3	MDC1	DYNLL2	KIF2A	KIF2C	KIF2B	BUB1B	UBE2V2	CDC20	BUB3	MAD2L1	CLASP2	PSMD8	PSMD9	CDC45	PSMD6	PSMD7	PSMD4	PSMD5	DYNC1I1	PSMD2	PSMD3	PSMD1	PSMA5	CENPE	PSMA6	BABAM1	PSMA3	HERC2	PSMA4	UIMC1	PSMA1	PSMA2	WHSC1	PSME3	PSME4	RNF168	PSME1	RPS27	RNF8	PSME2	BRCC3	TP53BP1	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	BRE	FAM175A	YWHAB	PSMB10	PSMA7	XPO1	PSMA8	PSMB6	PSMB7	PIAS4	UBE2N	PSMB4	PSMB5	YWHAZ	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	SUMO1	PKMYT1	ERCC6L	ZWILCH	CASC5	KNTC1	MAD1L1	CDCA8	PMF1	SKA1	SKA2	DSN1	TP53	RCC2	NDC80	ZWINT	AHCTF1	SGOL2	SGOL1	NUF2	SPDL1	CDC7	NDEL1	NUDC	RANGAP1	INCENP	BIRC5	ITGB3BP	MIS12	CENPA	AURKB	NSL1	CENPC	BUB1	CENPT	CLSPN	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	CENPN	CENPO	B9D2	CENPP	CENPQ	SPC24	SPC25	PPP1CC	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	RAD17	RAD1	WEE1	DNA2	RAD9B	RHNO1	ATR	RAD9A	RFWD2	ATM	MCM10	DBF4	YWHAQ	SFN	CDKN2A	YWHAH	RFC5	RFC3	RFC4	PPP2R5E	RFC2	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	CDKN1A	CDKN1B	PHF20	CHEK2	CHEK1	ZNF385A	CDC25A	PCBP4	MDM2	MDM4	CDC25C	GTSE1	NUP107	PPP2R1B	HIST3H2BB	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	NUP160	NUP85	YWHAE	PPP2R1A	HIST1H4K	HIST1H4L	YWHAG	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	
APC C:CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS%REACTOME%R-HSA-176409.2	APC C:Cdc20 mediated degradation of mitotic proteins	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	PSMB10	PSMA7	ANAPC4	PSMA8	ANAPC5	PSMB6	PSMB7	CCNB1	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	PSMC2	UBE2S	CDC16	CDK1	PTTG1	BUB1B	CDC20	BUB3	MAD2L1	NEK2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
GAP-FILLING DNA REPAIR SYNTHESIS AND LIGATION IN TC-NER%REACTOME DATABASE ID RELEASE 74%6782210	Gap-filling DNA repair synthesis and ligation in TC-NER	POLK	XRCC1	LIG3	UBA52	UBB	UBC	RPS27A	HMGN1	AQR	ZNF830	UVSSA	ERCC8	TCEA1	RPA1	RPA2	RPA3	PRPF19	XAB2	CCNH	CUL4A	DDB1	POLR2A	POLR2B	POLR2C	CUL4B	PPIE	POLR2D	POLR2E	RBX1	POLR2F	POLR2G	POLR2H	RFC5	POLR2I	RFC3	POLR2J	PCNA	POLR2K	RFC4	POLR2L	GTF2H1	RFC1	GTF2H2	LIG1	GTF2H3	RFC2	GTF2H4	ISY1	POLE4	POLD3	GTF2H5	USP7	POLD4	CDK7	POLE2	POLD1	ERCC3	POLE3	POLD2	POLE	ERCC2	ERCC6	EP300	MNAT1	
REPLICATION OF THE SARS-COV-1 GENOME%REACTOME%R-HSA-9682706.2	Replication of the SARS-CoV-1 genome	RB1	ZCRB1	GSK3A	DDX5	GSK3B	VHL	
FGFR1 MUTANT RECEPTOR ACTIVATION%REACTOME DATABASE ID RELEASE 74%1839124	FGFR1 mutant receptor activation	FGF20	FGF23	GAB2	PIK3R1	PIK3CA	ERLIN2	ZMYM2	FGFR1OP2	TRIM24	MYO18A	STAT5A	LRRFIP1	STAT5B	BCR	BAG4	FGF1	CUX1	CPSF6	FGF2	STAT1	STAT3	FGF4	FGFR1OP	FGF6	FGFR1	FGF9	
TRANSFERRIN ENDOCYTOSIS AND RECYCLING%REACTOME DATABASE ID RELEASE 74%917977	Transferrin endocytosis and recycling	ATP6V0C	ATP6V1B1	ATP6V1A	ATP6V0A2	ATP6V1H	ATP6V0A4	ATP6V1G3	ATP6V0E2	ATP6V1D	ATP6V1C1	ATP6V1C2	ATP6V0A1	ATP6V1F	MCOLN1	TF	STEAP3	TFRC	HFE	TCIRG1	ATP6V1E1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	ATP6AP1	TFR2	ATP6V1B2	ATP6V0D1	STEAP2	ATP6V0D2	
HEME BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%189451	Heme biosynthesis	ABCG2	ALAS1	ALAS2	FECH	COX15	UROS	CPOX	PPOX	ALAD	UROD	ALB	HMBS	COX10	
P53-DEPENDENT G1 DNA DAMAGE RESPONSE%REACTOME DATABASE ID RELEASE 74%69563	p53-Dependent G1 DNA Damage Response	PSMA6	PSMA3	CDKN1A	PSMA4	CDKN1B	PSMA1	PHF20	PSMA2	CHEK2	PSME3	PSME4	ZNF385A	PSME1	PSME2	PCBP4	PSMD10	MDM2	PSMB11	MDM4	UBA52	PSMD12	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	CCNE2	CCNE1	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CDK2	RFWD2	ATM	CDKN2A	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	TP53	
CYSTEINE FORMATION FROM HOMOCYSTEINE%REACTOME%R-HSA-1614603.2	Cysteine formation from homocysteine	CBS	CTH	
GSD 0 (MUSCLE)%REACTOME%R-HSA-3828062.3	GSD 0 (muscle)	GYS1	GYG1	
DEFECTIVE F8 BINDING TO THE CELL MEMBRANE%REACTOME DATABASE ID RELEASE 74%9672395	Defective F8 binding to the cell membrane	F8	
PRE-NOTCH EXPRESSION AND PROCESSING%REACTOME%R-HSA-1912422.1	Pre-NOTCH Expression and Processing	HIST2H2AC	H2AFJ	MAML3	MAMLD1	TNRC6C	MOV10	AGO3	H2AFZ	AGO4	H2AFX	H2AFV	AGO1	HIST2H2BE	SEL1L	AGO2	HIST4H4	TNRC6A	TNRC6B	HIST1H2BN	HIST1H2BM	HIST1H2BO	RAB6A	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	RFNG	POGLUT1	TMED2	POFUT1	B4GALT1	MFNG	ATP2A3	ATP2A2	ATP2A1	E2F1	ST3GAL4	ST3GAL3	NOTCH1	SNW1	TFDP1	TFDP2	HIST1H2AE	HIST1H2AD	FURIN	HIST3H2BB	HIST1H2AC	HIST1H2AB	SIRT6	ELF3	NOTCH3	NOTCH4	HIST1H2AJ	E2F3	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	LFNG	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	RUNX1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	CCND1	H3F3B	HIST1H4K	HIST1H4L	NOTCH2	MAML2	MAML1	JUN	KAT2B	H3F3A	RBPJ	KAT2A	H2BFS	ST3GAL6	HIST1H4A	HIST1H4B	PRKCI	HIST1H4H	HIST1H4I	CREBBP	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	TP53	HIST2H2AA4	
BIOLOGICAL OXIDATIONS%REACTOME DATABASE ID RELEASE 74%211859	Biological oxidations	SLC26A2	SLC26A1	CYP11A1	CYP7B1	MAOA	CHAC2	SULT1A1	GSTT2B	SULT1A4	SULT1A2	GSTM4	GSTM3	GSTM2	GSTM1	SULT1B1	GSTM5	SULT1C2	SULT1C4	AKR1A1	SULT1E1	GSTA5	GLYATL3	GSTA4	HSP90AB1	GLYATL2	GSTA3	GSTZ1	GLYATL1	GSTA2	ACSM1	GSTA1	CNDP2	ACSM2A	ACSM5	SULT6B1	ACSM4	GSTT2	GSTT1	GLYAT	ESD	ACSM2B	GGCT	GCLC	NAT1	NAT2	GCLM	PODXL2	OPLAH	SULT4A1	ABHD14B	IMPAD1	BPNT1	N6AMT1	MTRR	CYP1B1	NNMT	AHCY	GSTP1	TPMT	GSTO1	MTR	MAT2B	MAT1A	AS3MT	MAT2A	SULT1A3	CHAC1	NCOA1	NCOA2	SLC35B3	SLC35B2	SLC35D1	RXRA	GSTK1	UGT1A4	PTGES3	UGT2B10	UGT1A10	UGT2B11	UGT2B15	UGT2B17	UGT2B28	UGDH	ABHD10	UGP2	AHR	UGT1A5	CYP2C19	UGT2A3	UGT3A2	CYP3A4	ADH1C	CYP2C18	UGT2B4	ADH1A	UGT3A1	CYP3A5	CYP3A7	UGT1A3	CYP2B6	UGT1A8	CYP2A13	UGT2B7	CYP2D6	CYP26A1	UGT1A7	ADH4	CYP2F1	UGT1A6	CYP2J2	PAOX	ARNT2	CYP26B1	CYP3A7-CYP3A51P	CYP26C1	CYP3A43	ARNT	ALDH1A1	CYP2C9	CYP2A7	CYP2A6	CYP2C8	CYP2W1	CYP2S1	CYP1A2	CYP1A1	AHRR	CYP2E1	GGT7	ACY3	GGT6	ACY1	MGST3	MGST1	MGST2	AKR7L	AKR7A2	AKR7A3	CYP4V2	TBXAS1	PAPSS1	CYP4F12	SULT2A1	CYB5R3	GSTO2	CYP4A22	HPGDS	TPST2	PTGIS	TPST1	CYP4F22	PTGS1	CYP4A11	FDX1	FDXR	FDX1L	CYP7A1	CYP4F2	CYP4F3	UGT1A9	NR1H4	CYP4B1	CYP4F11	CYP4F8	CYP8B1	GSS	ALDH2	CYP46A1	AIP	CMBL	CYP2U1	CYP39A1	CYP27A1	ALDH3A1	POR	CES2	CES1	MAOB	ADH7	CYP19A1	ADH5	ADH6	CYP27B1	MARC2	MARC1	EPHX1	CYP11B2	CYP11B1	CYP2R1	CYP21A2	ACSS2	ADH1B	BPHL	ALDH1B1	ACSS1	CBR3	CYB5B	AOC3	NQO2	CES3	AOC1	AOC2	FMO1	FMO2	FMO3	AADAC	COMT	GGT1	CYP51A1	DPEP2	DPEP1	DPEP3	GGT5	TRMT112	POMC	CYP24A1	PAPSS2	UGT1A1	
SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS%REACTOME DATABASE ID RELEASE 74%6802946	Signaling by moderate kinase activity BRAF mutants	MAPK3	RAF1	CSK	PHB	CAMK2G	SRC	RAP1B	RAP1A	MARK3	KRAS	YWHAB	NRAS	FN1	CNKSR2	HRAS	APBB1IP	CNKSR1	MAP3K11	ITGB3	ARRB1	ARAF	ARRB2	MAPK1	FGB	FGA	ITGA2B	VWF	CAMK2A	PEBP1	KSR1	FGG	TLN1	KSR2	IQGAP1	JAK2	BRAP	BRAF	MAP2K1	MAP2K2	CAMK2B	VCL	CAMK2D	
MMR%REACTOME%R-HSA-5358508.1	MMR	PMS2	PCNA	RPA1	MSH3	RPA2	LIG1	MLH1	POLD3	MSH6	POLD4	RPA3	POLD1	MSH2	EXO1	POLD2	
MPS IIID - SANFILIPPO SYNDROME D%REACTOME%R-HSA-2206305.2	MPS IIID - Sanfilippo syndrome D	GNS	
SYNTHESIS OF PC%REACTOME DATABASE ID RELEASE 74%1483191	Synthesis of PC	PCYT1B	PCYT1A	CSNK2A1	STARD7	CSNK2A2	PHOSPHO1	CSNK2B	ABHD3	CHAT	CEPT1	BCHE	CHKB	CHKA	STARD10	CHPT1	PEMT	LPIN1	LPIN2	SLC44A5	LPIN3	ACHE	SLC44A3	SLC44A4	SLC44A1	SLC44A2	LPCAT1	PCTP	MFSD2A	
INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS%REACTOME DATABASE ID RELEASE 74%176033	Interactions of Vpr with host cellular proteins	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	AAAS	HMGA1	PSIP1	NUP160	NUP85	TPR	KPNA1	NUP88	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	NUP107	NUP153	SLC25A5	NUP188	SLC25A4	SLC25A6	BANF1	
LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME%REACTOME DATABASE ID RELEASE 74%9005891	Loss of function of MECP2 in Rett syndrome	CAMK4	TBL1X	HDAC1	TBL1XR1	SIN3A	HDAC3	PRKACA	NCOR2	NCOR1	GPS2	
GSD IB%REACTOME%R-HSA-3229133.2	GSD Ib	
REGULATION OF GLYCOLYSIS BY FRUCTOSE 2,6-BISPHOSPHATE METABOLISM%REACTOME DATABASE ID RELEASE 74%9634600	Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	PPP2CA	PFKFB2	PPP2CB	PFKFB1	PFKFB4	PFKFB3	PPP2R1A	PPP2R1B	PRKACA	PRKACG	PPP2R5D	PRKACB	
REV-MEDIATED NUCLEAR EXPORT OF HIV RNA%REACTOME%R-HSA-165054.2	Rev-mediated nuclear export of HIV RNA	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	RANGAP1	RCC1	NUP50	XPO1	NUP205	NUP54	POM121	RANBP1	AAAS	NUP160	NUP85	TPR	NUP88	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	RAN	NUP107	NUP153	NUP188	
FOXO-MEDIATED TRANSCRIPTION OF CELL DEATH GENES%REACTOME%R-HSA-9614657.1	FOXO-mediated transcription of cell death genes	CITED2	PINK1	FASLG	BCL6	FOXO3	FOXO1	BCL2L11	NFYA	NFYB	NFYC	DDIT3	FOXO4	STK11	CREBBP	BBC3	EP300	
SYNTHESIS AND PROCESSING OF ENV AND VPU%REACTOME%R-HSA-171286.1	Synthesis and processing of ENV and VPU	FURIN	
TOXICITY OF BOTULINUM TOXIN TYPE C (BONT C)%REACTOME%R-HSA-5250971.1	Toxicity of botulinum toxin type C (BoNT C)	STX1B	STX1A	SNAP25	
RHO GTPASES ACTIVATE FORMINS%REACTOME DATABASE ID RELEASE 74%5663220	RHO GTPases Activate Formins	RCC2	DYNC1LI1	NDC80	DYNLL1	ZWINT	DYNC1LI2	CKAP5	AHCTF1	ZW10	SGOL2	SGOL1	NUF2	MAPRE1	SPDL1	SEC13	NDEL1	NUP133	NUDC	RANGAP1	PAFAH1B1	INCENP	BIRC5	DYNC1I2	ITGB3BP	MIS12	CENPA	AURKB	NSL1	CENPC	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	KIF18A	PPP2CA	CENPN	CLASP1	CENPO	SRF	PPP2CB	B9D2	CENPP	DYNC1H1	CENPQ	NUP43	SPC24	SPC25	RANBP2	NDE1	PLK1	RAC1	CLIP1	NUP37	PPP1CC	CDC42	DYNLL2	RHOC	RHOA	RHOB	KIF2A	KIF2C	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	CLASP2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	DYNC1I1	DIAPH1	CENPE	DAAM1	SCAI	DIAPH3	RPS27	MKL1	FMNL3	FMNL1	FMNL2	XPO1	NUP107	ACTB	ACTG1	EVL	PPP2R1B	DVL1	DVL2	ITGB1	DVL3	NUP160	NUP85	PFN1	PFN2	PPP2R1A	RHOD	ERCC6L	ZWILCH	CASC5	KNTC1	MAD1L1	CDCA8	PMF1	SKA1	SKA2	DSN1	
THE NLRP3 INFLAMMASOME%REACTOME DATABASE ID RELEASE 74%844456	The NLRP3 inflammasome	NFKB1	TXNIP	P2RX7	TXN	MEFV	SUGT1	PYCARD	HSP90AB1	PANX1	NFKB2	RELA	NLRP3	APP	PSTPIP1	CASP1	
MITOCHONDRIAL TRANSCRIPTION INITIATION%REACTOME%R-HSA-163282.2	Mitochondrial transcription initiation	TFAM	TFB2M	POLRMT	
CONSTITUTIVE SIGNALING BY NOTCH1 HD+PEST DOMAIN MUTANTS%REACTOME DATABASE ID RELEASE 74%2894862	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	MIB2	MIB1	CCNC	NCSTN	NEURL1	MAML3	MAMLD1	HDAC4	UBA52	HDAC5	NOTCH1	HDAC8	HDAC9	HDAC7	CDK8	HEY1	HEY2	CUL1	UBB	UBC	HDAC10	HDAC11	RPS27A	TBL1X	MYC	SNW1	HDAC2	HDAC1	HDAC3	TBL1XR1	HDAC6	NCOR2	NCOR1	RBX1	MAML2	MAML1	KAT2B	SKP1	PSEN2	RBPJ	ADAM10	KAT2A	DLL1	HEYL	DLL4	ADAM17	APH1A	NEURL1B	APH1B	CREBBP	EP300	HES1	HES5	JAG2	PSENEN	PSEN1	JAG1	
WNT5A-DEPENDENT INTERNALIZATION OF FZD4%REACTOME DATABASE ID RELEASE 74%5099900	WNT5A-dependent internalization of FZD4	AP2A2	PRKCB	FZD4	ARRB2	PRKCA	WNT5A	AP2M1	CLTC	CLTA	AP2B1	CLTB	PRKCG	DVL2	AP2A1	AP2S1	
MITOCHONDRIAL IRON-SULFUR CLUSTER BIOGENESIS%REACTOME DATABASE ID RELEASE 74%1362409	Mitochondrial iron-sulfur cluster biogenesis	FDX1	FDXR	FDX1L	HSCB	ISCA2	SLC25A37	ISCA1	FXN	SLC25A28	LYRM4	GLRX5	
DOWNREGULATION OF TGF-BETA RECEPTOR SIGNALING%REACTOME DATABASE ID RELEASE 74%2173788	Downregulation of TGF-beta receptor signaling	PPP1R15A	USP15	UBA52	NEDD4L	MTMR4	PMEPA1	SMAD2	SMURF2	SMAD3	SMURF1	TGFB1	UCHL5	TGFBR1	PPP1CA	XPO1	SMAD7	TGFBR2	BAMBI	STRAP	STUB1	UBB	UBC	RPS27A	PPP1CB	PPP1CC	
MRNA 3'-END PROCESSING%REACTOME DATABASE ID RELEASE 74%72187	mRNA 3'-end processing	SRSF11	CHTOP	UPF3B	MAGOHB	RNPS1	CPSF7	CPSF1	CPSF3	CSTF3	CSTF2	CPSF2	CSTF2T	WDR33	NUDT21	FIP1L1	CLP1	PCF11	PAPOLA	CSTF1	SYMPK	CPSF4	PABPN1	EIF4A3	CASC3	MAGOH	NCBP1	NCBP2	THOC1	THOC3	THOC2	THOC5	THOC7	CDC40	SRRM1	THOC6	DDX39A	DDX39B	SARNP	ZC3H11A	SRSF2	SRSF3	SRSF4	SRSF5	SRSF6	SRSF7	SLU7	SRSF9	FYTTD1	LUZP4	RBM8A	POLDIP3	SRSF1	U2AF1	U2AF1L4	U2AF2	DHX38	
OLIGOMERIZATION OF CONNEXINS INTO CONNEXONS%REACTOME%R-HSA-190704.1	Oligomerization of connexins into connexons	GJB2	GJB1	GJA1	
ALTERNATIVE COMPLEMENT ACTIVATION%REACTOME DATABASE ID RELEASE 74%173736	Alternative complement activation	C3	CFD	GZMM	CFB	
CLASSICAL KIR CHANNELS%REACTOME%R-HSA-1296053.1	Classical Kir channels	KCNJ12	KCNJ14	KCNJ2	KCNJ4	
THE IPAF INFLAMMASOME%REACTOME%R-HSA-844623.1	The IPAF inflammasome	NLRC4	CASP1	
FOXO-MEDIATED TRANSCRIPTION OF CELL CYCLE GENES%REACTOME DATABASE ID RELEASE 74%9617828	FOXO-mediated transcription of cell cycle genes	FOXG1	CDKN1A	CDKN1B	CAV1	FOXO3	FOXO1	PCBP4	KLF4	MSTN	SMAD4	SMAD2	RBL2	SMAD3	FOXO4	BTG1	GADD45A	CCNG2	
ERYTHROPOIETIN ACTIVATES STAT5%REACTOME%R-HSA-9027283.1	Erythropoietin activates STAT5	EPOR	LYN	JAK2	STAT5A	STAT5B	EPO	IRS2	
RAS SIGNALING DOWNSTREAM OF NF1 LOSS-OF-FUNCTION VARIANTS%REACTOME DATABASE ID RELEASE 74%6802953	RAS signaling downstream of NF1 loss-of-function variants	NRAS	SPRED3	SPRED2	HRAS	SPRED1	NF1	
TERMINATION OF TRANSLESION DNA SYNTHESIS%REACTOME DATABASE ID RELEASE 74%5656169	Termination of translesion DNA synthesis	POLK	UBA7	UBA52	POLH	UBB	UBC	RPS27A	UBE2L6	USP10	POLI	USP43	REV1	RFC5	KIAA0101	RFC3	ISG15	PCNA	RPA1	TRIM25	RFC4	RPA2	RFC1	RFC2	POLE4	POLD3	POLD4	RPA3	POLE2	POLD1	POLE3	POLD2	POLE	
COMPLEMENT CASCADE%REACTOME DATABASE ID RELEASE 74%166658	Complement cascade	CR1	IGKV2-28	IGKV1-12	IGKV3D-20	ELANE	IGKV2D-28	IGKV4-1	IGKV2D-30	VTN	IGKV3-11	IGKV5-2	C3AR1	CD81	C4BPA	C4BPB	C8B	C8A	CLU	C8G	CR2	CD46	CPB2	CFH	C5AR2	CFI	C5AR1	CPN2	CPN1	C5	FCN1	C6	CFD	C7	CRP	CD19	C1QB	C9	COLEC11	CFHR2	C1QA	CFHR1	FCN2	CFHR4	COLEC10	CD59	CFHR3	FCN3	CD55	CFHR5	C1S	C1R	C4B_2	C2	C3	C4B	IGHG4	C4A	IGHG1	IGHG2	MBL2	GZMM	MASP1	CFB	PROS1	C1QC	F2	SERPING1	
GABA RECEPTOR ACTIVATION%REACTOME%R-HSA-977443.4	GABA receptor activation	ADCY2	ADCY1	GABRA2	ADCY8	GABRQ	ADCY7	GABRA1	ADCY6	GABRA6	ADCY5	GABRA5	GABRA4	GNG12	GABRA3	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNAL	GNB5	NPTN	GNAT3	ARHGEF9	GNAI3	KCNJ2	KCNJ3	GNAI1	KCNJ4	GNAI2	GABBR2	KCNJ5	KCNJ6	GABBR1	KCNJ10	KCNJ12	KCNJ9	KCNJ15	KCNJ16	GNGT1	GNGT2	ADCY9	GABRG3	GABRG2	GNG3	GABRB3	GNG10	GABRB2	GABRB1	GNG2	GABRR3	GNG5	GABRR2	GNG4	GABRR1	GNG7	GNG8	ADCY4	ADCY3	
LXRS REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE%REACTOME%R-HSA-9031528.1	LXRs regulate gene expression linked to triglyceride lipolysis in adipose	RXRA	PLIN1	RXRB	NR1H2	NR1H3	
SYNTHESIS OF 12-EICOSATETRAENOIC ACID DERIVATIVES%REACTOME%R-HSA-2142712.2	Synthesis of 12-eicosatetraenoic acid derivatives	GPX1	GPX4	ALOXE3	ALOX12B	ALOX15	GPX2	ALOX12	
TFAP2 (AP-2) FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS%REACTOME%R-HSA-8866911.2	TFAP2 (AP-2) family regulates transcription of cell cycle factors	KDM5B	CDKN1A	MYC	TFAP2A	TFAP2C	
HIV INFECTION%REACTOME DATABASE ID RELEASE 74%162906	HIV Infection	NUP62	NDC1	SEC13	NUP133	UBA52	NUP50	NUP54	UBB	UBC	CXCR4	RPS27A	NUP43	RAE1	RANBP2	ARF1	NUP35	NUPL2	NUP37	SLC25A5	SLC25A4	SLC25A6	CCNK	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	CCNT2	PSMD8	GTF2A1	GTF2A2	PSMD9	GTF2B	PSMD6	TAF9	PSMD7	TAF1L	PSMD4	AK6	PSMD5	GTF2E1	PSMD2	GTF2E2	PSMD3	TAF7L	PSMD1	TAF9B	TAF15	TAF12	TAF13	PSMA5	TAF10	PSMA6	TAF11	PSMA3	TAF4B	PSMA4	TAF7	PSMA1	TAF6	PSMA2	TAF5	PSME3	TAF4	PSME4	TAF3	PSME1	TAF2	PSME2	TAF1	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	RCC1	PSMA7	NMT1	XPO1	NMT2	PSMA8	PSMB6	PDCD6IP	RNMT	PSMB7	PSMB4	RANBP1	XRCC6	PSMB5	RNGTT	XRCC5	PSMB2	PSMB3	PSMB1	HMGA1	PSMF1	PSIP1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	AP1G1	PACS1	PSMC4	AP1B1	PSMC1	AP1S2	PSMC2	AP1S1	AP1S3	HLA-A	XRCC4	B2M	CCR5	LIG4	AP1M2	CUL5	AP1M1	ELMO1	CD4	NELFB	LCK	CD28	RBX1	FYN	TSG101	VPS4B	VPS4A	MVB12B	MVB12A	VTA1	VPS37C	VPS37D	PAK2	VPS37A	VPS37B	CHMP2B	CHMP2A	CHMP4C	CHMP4B	ATP6V1H	UBAP1	CHMP3	CHMP4A	RANGAP1	CHMP6	CHMP7	VPS28	CHMP5	CTDP1	ELL	HCK	CCNT1	SUPT4H1	TCEB3	TCEB2	TCEB1	NELFA	NELFCD	TCEB3C	TCEB3CL	TCEB3B	NELFE	SUPT16H	SSRP1	SUPT5H	CDK9	TCEA1	TCEB3CL2	RAC1	DOCK2	PPIA	NEDD4L	NCBP1	NCBP2	FEN1	LIG1	NPM1	AP2A1	AP2A2	KPNA1	TBP	GTF2F1	GTF2F2	KPNB1	AP2M1	RAN	NUP107	NUP188	BANF1	FURIN	AP2S1	NUP214	NUP210	NUP93	AP2B1	NUP205	CCNH	POM121	AAAS	NUP160	NUP85	TPR	NUP88	GTF2H1	GTF2H2	NUP155	BTRC	GTF2H3	GTF2H4	GTF2H5	SKP1	CDK7	NUP153	ERCC3	ERCC2	MNAT1	CD8B	
SOS-MEDIATED SIGNALLING%REACTOME%R-HSA-112412.3	SOS-mediated signalling	NRAS	IRS1	SOS1	HRAS	IRS2	
ACTIVATION OF PPARGC1A (PGC-1ALPHA) BY PHOSPHORYLATION%REACTOME%R-HSA-2151209.1	Activation of PPARGC1A (PGC-1alpha) by phosphorylation	PRKAG3	PRKAB2	MAPK12	PRKAB1	PRKAA2	MAPK14	MAPK11	PRKAG1	PRKAG2	PPARGC1A	
RNA POLYMERASE II TRANSCRIPTION%REACTOME%R-HSA-73857.5	RNA Polymerase II Transcription	ABCA6	TBL1X	SUZ12	CDK5R1	TBL1XR1	SMAD4	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	DEK	BLK	ELF1	ELF2	PAX5	YWHAB	YWHAZ	MAPK14	MAPK11	LSM10	LSM11	INTS1	INTS3	INTS2	INTS5	INTS4	INTS7	INTS6	INTS9	BGLAP	INTS8	INTS12	INTS10	ICE1	ICE2	SSU72	NABP2	NABP1	TAF8	ELL2	ELL3	RBX1	ZC3H8	RPRD2	RPAP2	ASUN	VWA9	CPSF3L	RPRD1B	RPRD1A	POU2F2	TGFA	GLI3	GLI2	GRIN2B	ITCH	BIRC5	AURKB	KIT	CSF2	ITGA2B	GPI	APAF1	NEDD4L	IL2	SMURF2	SMURF1	IL3	SMAD7	STUB1	PML	CCND2	RFC5	RFC3	PCNA	RFC4	RFC2	PPP2R5C	MET	CAMK2B	CAMK2D	CDKN1A	CDKN1B	PHF20	CAMK2G	CHEK2	PTPN11	CHEK1	ZNF385A	PCBP4	MDM2	IL2RA	MDM4	BTG2	KRAS	TNKS1BP1	CNOT6L	PRMT1	CDC25C	RBL2	RBL1	PLAGL1	E2F4	E2F7	E2F8	PLK3	NPM1	GADD45A	ARID3A	CNOT10	CNOT4	CNOT7	RGCC	CNOT1	CNOT11	CNOT2	CNOT3	CNOT8	ATF2	UBE2D3	MEF2C	ZNF17	ZNF287	ZNF18	RBFOX1	ZNF285	ZNF19	IRAK1	ZNF282	ZNF10	ZNF12	MAP2K6	ZNF14	JUN	AR	CLDN5	ZNF28	ZNF274	ZNF273	ZNF20	ZNF23	ZNF25	USP2	ZNF26	ZNF268	PPARGC1B	ZNF267	ZNF266	ZNF264	ZNF263	NR2F1	ZNF34	NR0B2	NR2F6	FOS	ZNF30	ZNF257	BCL2L11	ZNF256	ZNF496	ZNF254	ZNF253	ZNF493	ZNF492	ZNF250	UCMA	ZNF490	ZNF43	TNFRSF10D	ZNF45	HEY1	ZNF41	HEY2	CTLA4	ZNF248	ZNF486	ZNF485	ZNF484	CASP10	ZNF483	ACTL6B	RING1	CASP2	ZNF480	ACTL6A	SIRT3	ZNF479	ZNF235	ZNF234	ZNF233	PPARD	ZNF473	PTPN4	ZNF230	SERPINB13	ZNF471	ZNF470	HTT	ZNF227	ZNF468	ZNF226	ZNF225	ZNF224	ZNF223	ZNF222	MEN1	ZNF461	ZNF460	USP9X	ZNF77	ZNF79	SKI	ZNF70	ZNF71	ZNF74	AGRP	ZNF699	TFAP2A	ZNF215	TFAP2B	ZNF214	WWOX	ZNF697	TFAP2C	ZNF213	TFAP2D	ZNF696	TFAP2E	ZNF212	CITED1	ZNF454	CITED2	ZNF211	CITED4	ZNF692	YEATS4	ZNF691	RORC	MT-CO1	RORA	RORB	CTGF	TACO1	ZNF208	ZNF205	COX6A1	ZNF689	ZNF688	ZNF446	ZNF445	COX6B1	ZNF202	COX7A2L	SCO1	ZNF443	SCO2	ZNF200	ZNF684	MT-CO2	ZNF442	ZNF441	MT-CO3	ZNF682	ZNF440	ZNF681	COX19	ZNF680	COX16	ZFP69B	FOXP3	MAF	ZNF439	COX18	ZNF679	ZNF678	COX11	ZNF436	COX14	ZNF677	ZNF676	ZNF675	ZNF433	PVALB	ZNF432	SURF1	ZNF431	KMT2E	ZNF430	ZNF671	ZNF670	DLX5	DLX6	CYCS	KMT2B	FOXO6	FOXO4	ATXN3	COX20	GTF2A1	ZKSCAN7	COX7B	GTF2A2	MOBP	COX4I1	GTF2B	ZNF429	TAF9	ZKSCAN8	TAF1L	ZNF669	AK6	ZKSCAN3	COX7C	GTF2E1	ZNF668	GTF2E2	ZNF426	COX8A	TAF7L	ZKSCAN5	TAF9B	ZNF667	TAF15	ZNF425	TAF12	ZKSCAN4	TAF13	ZNF665	TAF10	ZNF664	TAF11	SOCS4	TAF4B	ZKSCAN1	TAF7	ZNF662	TAF6	ZNF660	TAF5	BDNF	TAF4	FBXO32	TAF3	ZNF419	TAF2	SP1	TAF1	ZNF418	ZNF417	ZNF658	ZNF416	ZNF415	ZNF655	SP7	ITGAL	ZNF649	YAF2	ZNF641	NKX3-2	COX5B	TRIM63	COX5A	TNFRSF18	HAND2	PPM1D	ZNF627	ZNF626	ZNF625	ZNF624	ZNF621	NDUFA4	ZNF620	E2F6	ZNF860	MGA	COX6C	TBX5	LRPPRC	PINK1	ZNF619	SST	ZNF616	ZNF615	ZNF614	ZNF613	ZNF611	ZNF610	TRIM33	SMARCB1	UXT	LGALS3	ZNF729	TRIM28	ZNF727	ZNF726	EPC1	ZNF721	ZNF720	SMARCC1	SMARCC2	ZFP1	ZFP2	ZNF716	ZNF713	ZNF711	ZNF710	ZNF324B	L3MBTL2	FOXG1	ZNF709	ZNF708	ZNF707	ZNF706	ZNF704	ZNF703	ZNF701	ZNF700	HIVEP3	SMARCA2	ITGBL1	MSTN	BMI1	HNF4A	SREBF1	PBRM1	SATB2	RXRB	ZFP14	ZNF585B	RXRG	ZNF585A	CCNG2	ZFP28	PRDM7	NPPA	ARID2	G6PC	MSX2	ZNF99	ZNF92	GPRIN1	ZFHX3	AUTS2	VDR	CAV1	BMP2	DPY30	TGIF1	RBM14	TGIF2	CAT	CAMK2A	RETN	LEF1	TCF7	RNF2	RRM2	ZNF804B	ZNF175	SERPINE1	ZSCAN32	ZNF169	JUNB	RNF111	ZNF705G	ZNF705D	MYB	ZNF160	ZNF705A	ZSCAN25	ZNF157	ZNF398	ZNF155	TCF7L2	ZNF154	TP53	ZNF394	TCF7L1	NKX2-5	ZFPM1	NR2C2AP	PHC2	ZNF141	ZNF383	GATA4	PHC1	GATA3	FOXO1	ZNF140	GATA2	ZNF382	GATA1	SETD1B	SETD1A	NR1D2	TNRC6C	MOV10	CDC7	ABL1	AGO3	NR1D1	AGO4	NFE2	PHC3	ZNF37A	CBX5	AGO1	ZNF138	PRDX2	ZNF136	AGO2	PRDX1	ZNF135	SOD2	ZNF133	BTG1	RSPO3	CDK5	CTNNB1	ZNF124	TEAD2	TNRC6A	ZIK1	TNRC6B	TEAD3	TEAD4	BRD2	ZNF724P	ZNF599	ZNF114	ZNF597	ZNF596	ZNF112	ZNF350	ZNF589	ZNF347	ZNF587	FOXO3	ZIM2	ZNF586	ZIM3	ZNF101	ZNF343	ZNF100	SIN3A	ZNF584	ZNF583	ZNF582	PCGF6	PCGF5	WWP1	ZNF33B	ZNF33A	RYBP	ZNF337	BRIP1	ZNF577	HDAC2	EXO1	ZNF334	HDAC1	ZNF333	TOPBP1	ATRIP	ZNF573	BARD1	ZNF331	RMI2	ZNF571	RMI1	WRN	ZNF570	HUS1	ZFP30	ZNF569	ZNF568	ZNF567	RAD17	ZNF566	RAD1	ZNF324	ZNF565	RAD9B	DNA2	RHNO1	ZFP37	ZNF564	ATR	ZNF563	RAD9A	ZNF562	ZNF320	ZNF561	ZNF560	NFATC2	NRBP1	ZNF559	ZNF317	ZNF558	ZNF557	PGR	ZNF799	ZNF556	ERBB2	ZNF555	ZNF554	ATM	ZNF311	ZNF552	FKBP5	MYL9	ZNF551	ZNF793	ZNF550	PTPN1	ZNF792	CSF1R	ZNF791	ZNF790	KRBA1	KRBOX4	ZNF549	YWHAQ	ZNF548	ZNF547	SFN	ZNF546	BID	ZNF304	YWHAH	ZNF544	ZNF302	ZNF786	ZNF543	ZNF785	SKIL	ZNF300	ZNF540	ESRRA	STAT1	ZNF782	ESRRB	ESRRG	ZFP69	PHAX	ZNF778	ZNF777	ZNF776	ZNF775	ZNF774	ZNF773	ZNF530	ZNF772	ZNF771	ZNF770	SIN3B	ZNF529	ZNF528	ZNF764	ZNF521	LBR	MAPK3	CR1	ZNF75D	ZFP90	ZNF75A	ZNF519	ZNF517	ZNF514	ZNF510	ZNF750	HDAC4	SMARCD1	HDAC5	SMARCD2	HDAC8	HDAC9	HDAC7	EGFR	ZNF749	ZNF506	ZNF747	ZNF746	ZNF500	ZNF740	SMARCE1	ZNF738	ZNF737	ZNF736	ZNF735	ZNF732	ZNF730	HDAC10	HDAC11	TXNIP	ZNF607	ZNF606	ZNF605	TXN	ZNF600	SOX9	RUNX3	VEGFA	CGA	ZNF839	HKR1	TWIST2	TWIST1	OCLN	PRMT6	ZNF2	ZNF3	NPY	TJP1	ZNF354A	ZNF354C	ZNF354B	LMO1	LMO2	ATP1B4	LIFR	KCTD6	CBX8	SMAD1	CBX6	CBX4	CBX2	SMAD6	ESR2	NR4A2	APOE	NR4A1	NR4A3	THRB	THRA	SLC2A3	NR2E1	OPRM1	NR1H2	ARID1A	ARID1B	ZNF197	ZNF195	NR2C2	THBS1	NR2C1	ZNF189	ZNF286A	ZNF184	ZNF180	OPRK1	CASP1	YWHAE	POMC	PPP2R1A	PRKACA	YWHAG	SKP1	DGCR8	UBA52	CUL1	AURKA	CCNB1	CPSF7	UBB	CPSF1	CPSF3	CSTF3	CSTF2	UBC	CPSF2	CSTF2T	BRCA1	WDR33	NUDT21	RPS27A	NBN	FIP1L1	CLP1	TOP3A	PCF11	PAPOLA	CSTF1	SYMPK	BLM	RBBP8	RPA1	RPA2	MRE11A	MLH1	CENPJ	CDK1	RAD50	RAD51	RPA3	MDC1	CCNK	CEBPB	TP53RK	EHMT1	NOC2L	GLS	TP53AIP1	PIP4K2A	IGFBP1	PIP4K2B	PIP4K2C	NFYA	TP63	NFYB	DAXX	NFYC	DDIT4	L3MBTL1	DDIT3	MEAF6	CDC73	NUAK1	TP53BP2	BANP	PRELID1	CRADD	TPX2	CDK12	CDK13	TP73	SETD9	CTR9	CHM	BBC3	WDR61	RTF1	ING5	ING2	AIFM2	PRMT5	LEO1	BRD1	DDB2	IL6	RAD51D	PLK2	SGK1	PMS2	BRD7	TIGAR	HIPK1	POU4F1	PAF1	POU4F2	HIPK2	TTC5	CCNG1	CCNT2	PRDM1	SESN3	SESN2	BNIP3L	USP7	G6PD	IGFBP3	MSH2	FANCD2	KAT6A	MAPKAPK5	NDRG1	SMYD2	PMAIP1	BCL2L14	ZNF420	FANCI	BRPF1	SLMO1	BRPF3	TNFRSF10C	FANCC	TP53I3	BCL6	JMY	PIN1	PPP1R13B	DYRK2	PTEN	TRIAP1	PIDD1	CASP6	PPP1R13L	GPX2	RABGGTB	RABGGTA	RRM2B	TMEM219	TMEM55B	RNF34	GLS2	NLRC4	TP53INP1	RNMT	RFFL	RNGTT	TXNRD1	SIRT1	CSNK2A1	SRC	CSNK2A2	HDAC6	BAX	NELFB	CSNK2B	SMAD2	SMAD3	TGFB1	NOTCH2	MAML2	MAML1	RBPJ	DLL1	EP300	HES1	JAG1	CREB1	MAML3	MAMLD1	GRIA2	GRIN2A	CAMK4	GPAM	EIF4A3	CASC3	MAGOH	NCBP1	NCBP2	THOC1	THOC3	THOC2	THOC5	THOC7	CDC40	SRRM1	THOC6	DDX39A	DDX39B	SARNP	ZC3H11A	SRSF2	SRSF3	SRSF4	SRSF5	SRSF6	SRSF7	SLU7	SRSF9	FYTTD1	LUZP4	RBM8A	POLDIP3	SRSF1	U2AF1	U2AF1L4	U2AF2	DHX38	SRSF11	CHTOP	UPF3B	MAGOHB	RNPS1	GTF2F1	GTF2F2	CPSF4	YES1	PARP1	PABPN1	RB1	PPP2R1B	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	PRKCB	HIST1H2AJ	HIST2H3A	INS	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	CCNH	EHMT2	H2AFB1	CHD4	CHD3	HIST1H3J	HIST1H3A	RBBP4	HIST1H3F	HIST1H3G	HIST1H3H	RBBP7	HIST1H3I	MTA2	HIST1H3B	HIST1H3C	MBD3	HIST1H3D	HIST1H3E	GTF2H1	GTF2H2	AFF4	H3F3B	GTF2H3	MLLT1	GTF2H4	HIST1H4K	GATAD2B	MLLT3	HIST1H4L	SUPT6H	GTF2H5	GATAD2A	IWS1	EAF1	KAT2B	EAF2	H3F3A	CDK7	KAT2A	H2BFS	ERCC3	HIST1H4A	SPI1	HIST1H4B	ERCC2	HIST1H4H	HIST1H4I	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	SETD8	NOP2	HIST2H2AC	H2AFJ	UBE2D1	CDC23	CDC26	CDC27	SKP2	ANAPC7	H2AFZ	UBE2E1	H2AFX	CCNA2	H2AFV	PPARGC1A	CCNA1	HIST2H2BE	CCNE2	CCNE1	HIST4H4	ANAPC4	ANAPC5	EZH2	ANAPC1	HIST1H2BN	HIST1H2BM	MED16	ANAPC2	MED15	ANAPC15	HIST1H2BO	ANAPC16	HIST1H2BJ	MED17	ANAPC10	HIST1H2BI	MED12	ANAPC11	HIST1H2BL	MED14	FZR1	HIST1H2BK	MED13	PPP2CA	MED10	HIST2H4A	PPP2CB	HIST2H4B	MAPK1	UBE2C	MED27	MED26	UBE2S	CDC16	CDK2	MED23	MED25	MED24	MED20	PPARG	PPARA	YY1	KMT2D	IHH	KMT2A	KMT2C	MED30	MED31	CRH	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	AXIN1	E2F1	PSMA5	PSMA6	PSMA3	PSMA4	RQCD1	PSMA1	CCNC	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PRKCQ	PSMD13	NOTCH1	MAX	PSMB10	PSMA7	MYBL2	E2F5	RELA	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	GAMT	NFKB1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PCK1	PSMC1	PSMC2	WWTR1	SMARCA4	SNW1	KDM5B	HNF4G	HSPD1	SUMO1	PITX2	UBE2I	ATAD2	KCTD1	ESR1	KCTD15	NR5A1	YAP1	TNFRSF10B	RXRA	NOTCH3	NOTCH4	TNFRSF10A	PERP	FASLG	FAS	SOCS3	IFNG	CCND3	PRR5	PDPK1	MAPKAP1	ITGA5	MTOR	AKT2	GPS2	AKT3	MLST8	AKT1	RICTOR	STEAP3	GSK3B	CCND1	CDK4	TCF3	LDB1	CREBBP	EED	CTDP1	ELL	CCNT1	SUPT4H1	TCEB3	TCEB2	VENTX	TCEB1	CARM1	NELFA	GAD1	CDKN2B	NELFCD	GAD2	TCEB3C	TCEB3CL	SNRPD3	TCEB3B	NELFE	MYC	SUPT16H	SSRP1	SUPT5H	CDK9	TCEA1	SLBP	TCEB3CL2	MED1	MED8	MED4	MED6	MED7	SRRT	COL1A1	PRKAA1	PRKAA2	CBX3	RARG	PRKAG1	PRKAG2	ASH2L	PRKAG3	RPTOR	STK11	SLC38A9	PRKAB2	TEAD1	TSC2	TCF12	TSC1	PRKAB1	PPM1A	NCOR2	SNRPG	NCOR1	RRAGA	TAL1	RRAGC	RARA	SNRPE	RRAGB	RARB	SNRPF	RHEB	RRAGD	LAMTOR2	CDK6	CDKN2A	LAMTOR1	LAMTOR4	SNRPB	LAMTOR3	LAMTOR5	PCGF2	GCK	CBFB	PLXNA4	CTSV	CDK8	CNOT6	CTSL	SNAPC5	CTSK	SNAPC1	SNAPC2	SNAPC3	WDR5	SNAPC4	ZNF143	POU2F1	TBP	TRPC3	MMP13	TFDP1	TFDP2	SMARCD3	HDAC3	SPP1	RBBP5	NR3C1	ITGA4	KLF4	KAT5	SOX2	RUNX1	GP1BA	PF4	
STAT5 ACTIVATION%REACTOME%R-HSA-9645135.3	STAT5 Activation	PTPN11	STAT5A	STAT5B	FLT3LG	GAB2	FLT3	
BREAKDOWN OF THE NUCLEAR LAMINA%REACTOME DATABASE ID RELEASE 74%352238	Breakdown of the nuclear lamina	LMNB1	CASP6	
MITOTIC PROMETAPHASE%REACTOME%R-HSA-68877.5	Mitotic Prometaphase	CSNK1E	RCC2	TUBGCP4	DYNC1LI1	NDC80	NUMA1	TUBG2	DYNLL1	ZWINT	TUBG1	MZT2B	DYNC1LI2	STAG1	CKAP5	MZT2A	TUBA4A	STAG2	NME7	AHCTF1	HAUS2	MZT1	ZW10	SGOL2	HAUS1	NCAPD2	AKAP9	SGOL1	NUF2	CEP63	WAPAL	MAPRE1	SPDL1	SEC13	NDEL1	NUP133	SFI1	NUDC	RANGAP1	SMC1A	PAFAH1B1	INCENP	SDCCAG8	BIRC5	DYNC1I2	ITGB3BP	DCTN2	SSNA1	MIS12	DCTN3	CENPA	AURKB	NSL1	CCNB2	CENPC	CCNB1	BUB1	CENPT	HAUS8	CENPU	HAUS7	CENPF	PRKAR2B	APITD1	CENPH	CEP70	CENPI	CEP72	TAOK1	CEP192	CENPK	CENPL	PCNT	CENPM	CEP76	KIF18A	PPP2CA	CENPN	CLASP1	CENPO	CEP78	PPP2CB	B9D2	PLK4	CENPP	DYNC1H1	CENPQ	ODF2	NUP43	SPC24	CEP152	SPC25	RANBP2	NDE1	PLK1	TUBB4B	TUBB4A	CLIP1	NEDD1	CENPJ	CDK1	NUP37	FGFR1OP	PPP1CC	CEP41	DYNLL2	KIF2A	KIF2C	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	CLASP2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	DYNC1I1	CENPE	RPS27	XPO1	NUP107	SMC4	SMC2	PPP2R1B	CSNK2A1	CSNK2A2	CSNK2B	NUP160	CEP57	NUP85	YWHAE	CETN2	CEP164	CCP110	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	NEK9	PRKACA	NINL	CEP290	NEK6	YWHAG	ERCC6L	CDK5RAP2	NEK7	ZWILCH	CASC5	OFD1	SMC3	HSP90AA1	KNTC1	MAD1L1	CEP135	CDCA5	CDCA8	EML4	PDS5B	TUBB	CEP131	TUBGCP2	PDS5A	NCAPG	PMF1	HAUS4	SKA1	NCAPH	HAUS3	CSNK1D	SKA2	TUBGCP5	DSN1	TUBGCP6	HAUS6	RAD21	TUBGCP3	HAUS5	
MATURATION OF PROTEIN M%REACTOME DATABASE ID RELEASE 74%9683612	Maturation of protein M	
SIGNALING BY INTERLEUKINS%REACTOME%R-HSA-449147.11	Signaling by Interleukins	RALA	UBA52	CUL1	UBB	UBC	RPS27A	STAT5A	STAT5B	PIK3CD	IRS2	PIK3CB	VAV1	CRKL	MAOA	RAPGEF1	JAK2	CXCL8	CCL2	TALDO1	IL10	IL6	GSTA2	IL7R	BCL6	GSTO1	RPLP0	YWHAZ	MAPKAPK2	IRAK2	STXBP2	HSPA8	CCR5	MAPK14	MAPK11	IRS1	CD4	SMAD3	TGFB1	NOS2	RBX1	FCER2	CREB1	JAK3	JAK1	ICAM1	DUSP4	ITGAX	GAB2	BIRC5	DUSP6	DUSP7	VCAM1	HCK	PTPN12	MUC1	CSF2	IL5RA	FGF2	SDC1	VIM	IL1RL1	IL33	MAP2K1	HGF	CSF2RB	CSF2RA	RAP1B	IL2	IL3	IL5	BCL2L1	CNTFR	CNTF	ANXA1	IL20RA	FPR1	IL20RB	IL22RA2	IL31RA	IL22RA1	HAVCR2	PPP2R5D	SERPINB2	ANXA2	ZEB1	CCL11	CTF1	STX3	CCL19	IL12RB1	IL12RB2	CCL22	IL3RA	CCL20	IL10RB	IL10RA	CLCF1	ALOX15	CRLF1	CSF3	STAT6	CSF1	IL2RG	PIM1	CDKN1A	IL13RA2	IL13RA1	TXLNA	FSCN1	IL6ST	PTPN11	BOLA2B	HNRNPDL	NDN	MCL1	IL2RA	SOCS5	IL2RB	CXCL10	LCP1	PTPRZ1	PTPN7	CCL5	CCL4	CCL3	PDCD4	IL23R	IL27RA	IL12B	IL12A	LGALS9	IL15RA	IL23A	BOLA2	EBI3	CCR1	LIF	IFNLR1	GRB2	IL22	IL20	IL25	IL26	IL24	IL27	CCR2	IL11	IL15	IL19	IL16	IL17RE	OSMR	YES1	IL17RC	IL17RB	IL17RA	CANX	OPRD1	IL32	IL31	IL34	OSM	BATF	IL17F	IL17C	PPP2R1B	IL17A	INPPL1	IL4R	IL11RA	CCL3L1	CCL3L3	CNN2	IL1RN	IL9	IL36A	CXCL1	IL18RAP	CXCL2	IL36B	CA1	IL1R2	BLNK	IL36RN	IL9R	IL36G	IFNL2	IL1F10	IFNL1	IL4	PTK2B	TOLLIP	IFNL3	PTPN20	PTPN23	HIST2H3A	IL18BP	IL13	IL1RAPL1	IL1RL2	PTPN18	HIST2H3D	MAP3K3	HIST2H3C	IL37	PTPN13	PTPN14	IGHG4	PTPN9	PTPN5	IGHG1	PTPN2	IL18R1	ATF1	APP	HIST1H3J	ATF2	ELK1	MAP2K3	HIST1H3A	MEF2A	MAP2K4	MEF2C	HIST1H3F	HIST1H3G	HIST1H3H	VRK3	HIST1H3I	SIGIRR	HIST1H3B	MAPKAPK3	HIST1H3C	HIST1H3D	HIST1H3E	AGER	HSP90B1	SOCS1	IRAK1	S100A12	MAP2K7	MAP2K6	JUN	NFKB2	MYD88	CISH	SOCS2	ITGAM	ITGB2	HMGB1	NKIRAS1	NKIRAS2	LBP	TEC	CD36	DUSP3	ALOX5	SQSTM1	RIPK2	IRAK3	LMNB1	IRAK4	FOS	MTAP	TBK1	PELI1	NANOG	PELI3	PELI2	NOD1	NOD2	MAPK9	MAPK8	MAPK7	S100B	PPP2CA	MAPK10	TNIP2	PPP2CB	SAA1	PTPN4	MAPK1	TNFRSF1A	TCP1	ARF1	RORC	RORA	TNFRSF1B	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	HIF1A	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	CAPZA1	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	TRAF6	PSMB11	PSMD12	IGHE	PSMD11	PSMD14	UBE2V1	PSMD13	PSMB10	PSMA7	RELA	LYN	PSMA8	PSMB6	PSMB7	UBE2N	PSMB4	TAB3	PSMB5	STX1A	TAB2	PSMB2	TAB1	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	SMARCA4	NFKBIB	MIF	HSPA9	SOD1	FASLG	SOCS3	IFNG	PTPN6	ITGB1	CD86	IL6R	FN1	CD80	PIK3R3	PIK3R2	PIK3R1	PIK3CA	LCK	AKT1	MAP3K8	FYN	CCND1	MSN	JUNB	RPS6KA5	TP53	PAK2	GATA3	FOXO1	HMOX1	SOD2	LCN2	RAG2	RAG1	TSLP	IL7	BRWD1	MYC	CRLF2	FOXO3	HNRNPF	CDC42	PTAFR	PTGS2	COL1A2	PPIA	HNRNPA2B1	IRF4	CSF1R	SYK	CRK	BCL2	STAT1	STAT3	CSF3R	TNF	CFL1	RPS6KA3	RPS6KA2	SNRPA1	RPS6KA1	MAPK3	SHC1	CBL	SOS1	AIP	CASP3	SNAP25	CTSG	TIMP1	INPP5D	POU2F1	MMP1	VEGFA	MMP2	MMP3	TWIST1	MMP9	IL18	IL1A	IL1B	LAMA5	LIFR	SOS2	VAMP7	CEBPD	VAMP2	STX4	OPRM1	IL1R1	TYK2	IL21	IL21R	STAT4	PITPNA	P4HB	SOX2	S1PR1	STAT2	CASP1	F13A1	POMC	PPP2R1A	PRKACA	BTRC	SKP1	RHOU	HSP90AA1	FBXW11	PRTN3	
GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE%REACTOME DATABASE ID RELEASE 74%210500	Glutamate Neurotransmitter Release Cycle	GLS	RIMS1	ARL6IP5	BZRAP1	UNC13B	RAB3A	PPFIA1	SLC1A1	SLC1A3	PPFIA4	SLC1A2	PPFIA3	PPFIA2	SYT1	SLC1A6	SLC1A7	CPLX1	GLS2	SLC38A2	STX1A	SNAP25	SLC17A7	VAMP2	
IRAK1 RECRUITS IKK COMPLEX UPON TLR7 8 OR 9 STIMULATION%REACTOME DATABASE ID RELEASE 74%975144	IRAK1 recruits IKK complex upon TLR7 8 or 9 stimulation	IKBKB	UBE2N	PELI3	PELI2	TRAF6	PELI1	IKBKG	IRAK1	CHUK	UBE2V1	
DEFECTIVE SLC5A5 CAUSES THYROID DYSHORMONOGENESIS 1 (TDH1)%REACTOME%R-HSA-5619096.1	Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1)	SLC5A5	
MAP KINASE ACTIVATION%REACTOME DATABASE ID RELEASE 74%450294	MAP kinase activation	RPS6KA1	RIPK2	MAPK3	FOS	CREB1	DUSP4	TRAF6	UBA52	UBE2V1	DUSP6	DUSP7	CUL1	UBE2N	UBB	TAB3	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	NFKB1	PPP2CA	MAPK10	TNIP2	PPP2CB	MAPK1	MAPK14	MAPK11	PPP2R1B	MAP2K1	ATF1	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	BTRC	IRAK1	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	FBXW11	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
REGORAFENIB-RESISTANT PDGFR MUTANTS%REACTOME DATABASE ID RELEASE 74%9674403	Regorafenib-resistant PDGFR mutants	PDGFRA	
A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS%REACTOME DATABASE ID RELEASE 74%1971475	A tetrasaccharide linker sequence is required for GAG synthesis	AGRN	B4GALT7	GPC1	B3GAT2	B3GAT1	XYLT2	XYLT1	SDC2	NCAN	BGN	VCAN	DCN	SDC4	CSPG5	B3GAT3	CSPG4	SDC3	GPC3	SDC1	GPC2	GPC5	B3GALT6	GPC4	HSPG2	GPC6	BCAN	
PI-3K CASCADE:FGFR4%REACTOME DATABASE ID RELEASE 74%5654720	PI-3K cascade:FGFR4	PTPN11	KLB	FRS2	FGF20	FGF1	FGF23	FGF2	GAB1	FGF4	FGF16	FGF6	FGF9	FGF19	FGF18	PIK3R1	FGFR4	PIK3CA	
ALANINE METABOLISM%REACTOME DATABASE ID RELEASE 74%8964540	Alanine metabolism	GPT	
NUCLEOTIDE-LIKE (PURINERGIC) RECEPTORS%REACTOME%R-HSA-418038.1	Nucleotide-like (purinergic) receptors	ADORA2B	ADORA1	P2RY11	P2RY12	GPR17	P2RY13	P2RY10	P2RY14	ADORA2A	LPAR4	P2RY6	P2RY4	LPAR6	P2RY2	ADORA3	P2RY1	
CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE%REACTOME DATABASE ID RELEASE 74%5620920	Cargo trafficking to the periciliary membrane	PDE6D	CCT3	BBS2	BBS1	CCT2	MKKS	ARL6	BBIP1	SSTR3	MCHR1	LZTFL1	TTC8	BBS10	BBS12	ARF4	TCP1	BBS9	BBS7	CCT8	BBS5	BBS4	CCT5	CCT4	EXOC8	ARL13B	EXOC7	INPP5E	RAB3IP	SMO	ASAP1	PKD2	PKD1	RAB11A	RHO	EXOC4	CNGA2	EXOC3	EXOC6	CNGA4	RAB8A	EXOC5	RAB11FIP3	EXOC2	EXOC1	UNC119B	RP2	CNGB1	ARL3	NPHP3	NPHP3-ACAD11	CYS1	GBF1	
SYNTHESIS OF LIPOXINS (LX)%REACTOME%R-HSA-2142700.4	Synthesis of Lipoxins (LX)	ALOX5AP	LTC4S	PTGR1	HPGD	ALOX12	ALOX5	
CHAPERONIN-MEDIATED PROTEIN FOLDING%REACTOME DATABASE ID RELEASE 74%390466	Chaperonin-mediated protein folding	TUBA4A	GNG12	GNG11	GNG13	DCAF7	GNAO1	CCT6B	KIF13A	FBXO4	FBXO6	RGS9	GNB2	GNAT1	RGS6	RGS7	CCNE2	GNB1	FBXW4	CCNE1	FBXW5	GNB4	FBXW10	GNB3	FBXW7	VBP1	GNB5	SPHK1	FBXW9	TUBA4B	NOP56	FBXW2	PFDN1	PFDN2	FBXL5	GNAT3	CCT3	FKBP9	PFDN4	PFDN5	CCT2	PFDN6	TUBAL3	USP11	GBA	AP3M1	CCT7	ARFGEF2	CCT6A	PDCL	FBXL3	TCP1	SKIV2L	RGS11	TUBB4B	TUBA8	CCT8	TUBB4A	WRAP53	CCT5	CCT4	ACTB	HDAC3	GNAI3	GAPDHS	GNAI1	GNAI2	LONP2	CSNK2A1	TUBA3E	TUBA1C	TUBB6	TUBA1B	CSNK2A2	TUBB3	TUBB1	XRN2	CSNK2B	GNAZ	TUBB2B	TUBB2A	GNGT1	GNGT2	GNAT2	TUBA1A	STAT3	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	TP53	
MITOCHONDRIAL FATTY ACID BETA-OXIDATION OF UNSATURATED FATTY ACIDS%REACTOME%R-HSA-77288.2	mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	ACADL	ECI1	DECR1	HADHB	HADHA	ACADM	
RESPONSE OF MTB TO PHAGOCYTOSIS%REACTOME%R-HSA-9637690.1	Response of Mtb to phagocytosis	RPS27A	MAPK3	KPNA1	DUSP16	KPNB1	HGS	MAPK1	PGK1	ATP6V1H	VPS33B	SFPQ	UBA52	CORO1A	RAB7A	TRIM27	ENO1	RNF213	GSK3A	UBB	RAB5A	NOS2	UBC	CTSG	
SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL (GPI)%REACTOME DATABASE ID RELEASE 74%162710	Synthesis of glycosylphosphatidylinositol (GPI)	PIGC	PIGB	DPM2	PIGA	PIGO	PIGN	PIGM	PIGP	PIGL	PIGZ	PIGG	PIGW	PIGF	PIGV	PIGY	PIGH	PIGX	
SELENOCYSTEINE SYNTHESIS%REACTOME%R-HSA-2408557.2	Selenocysteine synthesis	RPL41	SECISBP2	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	UBA52	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	RPS27A	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	EEFSEC	SARS	RPL4	RPL5	SEPSECS	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	PSTK	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	
TOLL LIKE RECEPTOR 5 (TLR5) CASCADE%REACTOME%R-HSA-168176.1	Toll Like Receptor 5 (TLR5) Cascade	RPS6KA1	RIPK2	MAPK3	IRAK4	FOS	CREB1	DUSP4	TRAF6	PELI1	UBA52	TLR10	UBE2V1	TLR5	DUSP6	DUSP7	CUL1	RELA	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	AGER	BTRC	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
NERVOUS SYSTEM DEVELOPMENT%REACTOME DATABASE ID RELEASE 74%9675108	Nervous system development	SH3KBP1	ROBO1	PRX	UBA52	UBB	UBC	CXCR4	AKAP5	DRP2	RPS27A	SCD5	CLASP1	PIK3CD	IRS2	PIK3CB	CDK5R1	ARHGAP39	ARHGAP35	NRCAM	DSCAM	EFNA5	EFNA4	RPL4	EFNB2	SDCBP	EFNB1	RPL5	EFNB3	RPL30	RPL3	EFNA1	RPL32	EFNA3	RPL31	RPL34	EFNA2	RPL10L	FES	RPL8	RPL10A	RPL9	RPL6	USP33	RPL7	RPS15	RPS14	RPS17	DCC	RPS16	GAP43	RPL18A	RPS19	DCX	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	CLASP2	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	PMP22	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	PABPC1	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	HSPA8	MAPK14	MAPK11	ARPC1B	EIF4G1	ARPC1A	RPL22L1	WASL	ACTB	FAU	ACTG1	NCK1	ACTR3	VAV3	ACTR2	RPL26L1	VAV2	CSNK2A1	SRC	MYO10	CSNK2A2	ARPC4	MYO9B	ARPC5	ARPC2	ARPC3	CSNK2B	PRKACG	PRKACB	RBX1	FRS2	PRKAR2A	TLN1	PSEN2	APH1A	APH1B	GRIN2B	PTK2	NUMB	ARTN	PSENEN	RET	CREB1	CNTN1	GFRA1	GAB2	GFRA3	GFRA2	GFRA4	RANBP9	GRIN1	ITGA2B	NRTN	MAP2K1	MAP2K2	SHC3	PSPN	GDNF	PTPRA	EIF4A3	CASC3	MAGOH	ITGB3	NCBP1	NCBP2	RBM8A	RASA1	MET	UPF3B	MAGOHB	NCAM1	RNPS1	PTPN11	MAPK12	CLTC	CLTA	YES1	SPTAN1	ANK2	PRKCA	ANK3	ANK1	SPTB	SPTBN4	SPTBN5	SPTA1	SPTBN1	SPTBN2	ITSN1	DPYSL4	DPYSL5	DPYSL2	DPYSL3	UNC5A	UNC5B	UNC5C	UNC5D	ISL1	DNM1	DNM2	NGEF	DNM3	AGAP2	PIP5K1C	L1CAM	MAPK8	MAPK7	UPF2	KIF4B	LYPLA2	KIF4A	MAPK1	DSCAML1	ZSWIM8	AGRN	NAB1	NAB2	MSI1	MAG	UTRN	RAP1GAP	CLTCL1	MBP	CXCL12	PTPRC	CNTNAP1	HSP90AB1	NCK2	ITGAV	NEO1	ADGRV1	ITGA2	ITGA1	PSMD8	PSMD9	ETF1	PSMD6	PSMD7	PSMD4	PSMD5	ITGA9	PSMD2	PSMD3	NTN4	PSMD1	NTN1	PSMA5	PSMA6	PSMA3	NELL2	PSMA4	PSMA1	PSMA2	EPHB2	PSME3	EPHB1	PSME4	SCN1B	PSME1	PSME2	EPHB4	SCN1A	EPHB3	PSMD10	EPHA5	PSMB11	EPHA4	PSMD12	EPHA7	PSMD11	PRKCQ	EPHA6	PSMD14	EPHA8	PSMD13	HFE2	PSMB10	PSMA7	LYN	PSMA8	SHTN1	PSMB6	KCNQ2	PSMB7	KCNQ3	PSMB4	EPHA1	PSMB5	PSMB2	EPHA3	PSMB3	EPHA2	PSMB1	PSMF1	EPHA10	SHFM1	PSMB8	SDC2	GSPT2	PSMB9	KALRN	PSMC5	GSPT1	PSMC6	RRAS	PSMC3	SCN3B	PSMC4	PSMC1	SCN3A	PSMC2	WWTR1	EGR2	SMARCA4	SCN2A	SCN2B	NRP1	NRP2	GIT1	CAP1	RGMB	SREBF2	RGMA	ENAH	ARHGEF7	YAP1	RELN	GPC1	PAK7	PAK6	PAK4	CAP2	CD72	MPZ	SCN9A	ITGB1	SH3GL2	PIK3R3	ITGA5	PIK3R2	PIK3R1	POU3F1	POU3F2	PIK3CA	DOK1	TYROBP	DOK4	DOK5	SCN8A	DOK6	PPP3CB	ARHGEF28	CACNA1D	FYN	CACNA1C	CACNA1H	DLG1	CACNA1G	DLG3	CACNA1I	DLG4	ADGRG6	CACNA1S	GSK3B	PRNP	CNTN6	ST8SIA4	MSN	CNTN2	LDB1	SCN5A	ST8SIA2	PAK1	RPS6KA5	PAK3	SCN4A	SCN4B	PAK2	LAMA2	LAMA1	CRMP1	HMGCR	ABL1	SLIT1	SCN7A	SLIT3	SLIT2	PDLIM7	CDK5	TCEB2	MAPK13	TCEB1	TRIO	ALCAM	SCN11A	HOXA2	NCAN	RAC1	SOX10	DOCK1	HDAC2	SCN10A	CDC42	FLRT3	ARHGEF11	ARHGEF12	ROCK1	RDX	SEMA4D	UPF3A	ROCK2	COL4A2	LIMK2	LIMK1	RHOC	COL4A1	RHOA	COL6A2	MYL12B	COL4A4	CLTB	RHOB	RND1	MYL6	GRB7	COL4A3	ERBB2	CHL1	COL6A1	MYH9	DOK2	MYH14	MYH11	PLXNB1	TEAD1	MYH10	MYL9	COL6A3	COL4A5	COL6A6	COL6A5	FARP2	SEMA5A	PLXND1	ADAM10	CFL1	GRB10	PLXNC1	SEMA6A	RPS6KA3	SEMA6D	RPS6KA6	PSEN1	CACNB1	RPS6KA2	CACNB2	RPS6KA1	CACNB3	MAPK3	CACNB4	SEMA7A	NCSTN	CUL2	PLXNA2	ABL2	PLXNA1	SRGAP3	COL9A1	COL9A3	COL9A2	SRGAP1	SHC1	PLXNA4	PLXNA3	GAB1	LAMC1	EGFR	NRAS	DAB1	PLCG1	LHX3	LHX2	SOS1	ITGA10	HRAS	PLXNB3	LHX4	LHX9	TREM2	AP2A1	VLDLR	AP2A2	TRPC7	TRPC5	TRPC6	TRPC3	AP2M1	MMP2	TRPC4	TRPC1	MMP9	EVL	SOS2	SEMA3A	AP2S1	SEMA3E	ABLIM1	ABLIM2	LAMB1	ABLIM3	SEMA4A	CYP51A1	NFASC	AP2B1	PITPNA	RPS6KA4	DAG1	TIAM1	EZR	PFN1	PFN2	PRKACA	MYL12A	HSP90AA1	VASP	SIAH2	SIAH1	ROBO2	
DEFECTIVE DPM1 CAUSES DPM1-CDG (CDG-1E)%REACTOME%R-HSA-4717374.1	Defective DPM1 causes DPM1-CDG (CDG-1e)	DPM1	DPM2	DPM3	
SIGNALING BY TGF-BETA RECEPTOR COMPLEX IN CANCER%REACTOME DATABASE ID RELEASE 74%3304351	Signaling by TGF-beta Receptor Complex in Cancer	SMAD2	SMAD3	TGFB1	TGFBR1	TGFBR2	FKBP1A	SMAD4	
TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS%REACTOME DATABASE ID RELEASE 74%2151201	Transcriptional activation of mitochondrial biogenesis	CREB1	HCFC1	TGS1	TFB1M	NR1D1	PPARGC1A	TFAM	TFB2M	POLRMT	SOD2	CARM1	GLUD1	SIRT3	GLUD2	TBL1X	CAMK4	IDH2	MED1	ACSS2	NCOA1	PPARA	ATP5B	NCOA2	NCOA6	SMARCD3	HDAC3	MEF2D	CRTC2	RXRA	CRTC3	CRTC1	MTERF1	GABPA	SIRT4	TBL1XR1	SIRT5	PPRC1	POLG2	PERM1	C10orf2	SSBP1	ATF2	NCOR1	MEF2C	NRF1	ALAS1	ESRRA	CYCS	HELZ2	CHD9	CREBBP	PPARGC1B	
INSULIN RECEPTOR RECYCLING%REACTOME%R-HSA-77387.3	Insulin receptor recycling	ATP6V0C	ATP6V1B1	ATP6V1A	ATP6V0A2	INS	ATP6V1H	ATP6V0A4	ATP6V1G3	ATP6V0E2	ATP6V1D	ATP6V1C1	ATP6V1C2	ATP6V0A1	ATP6V1F	INSR	TCIRG1	ATP6V1E1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	ATP6AP1	ATP6V1B2	ATP6V0D1	ATP6V0D2	
MINUS-STRAND DNA SYNTHESIS%REACTOME%R-HSA-164516.2	Minus-strand DNA synthesis	PPIA	
DEFECTIVE SLC5A1 CAUSES CONGENITAL GLUCOSE GALACTOSE MALABSORPTION (GGM)%REACTOME DATABASE ID RELEASE 74%5656364	Defective SLC5A1 causes congenital glucose galactose malabsorption (GGM)	SLC5A1	
ADRENOCEPTORS%REACTOME%R-HSA-390696.3	Adrenoceptors	ADRA2C	ADRA2A	ADRA1D	ADRB3	ADRB1	ADRB2	ADRA1B	ADRA1A	
VARIANT SLC6A14 MAY CONFER SUSCEPTIBILITY TOWARDS OBESITY%REACTOME%R-HSA-5619094.1	Variant SLC6A14 may confer susceptibility towards obesity	SLC6A14	
GLUTATHIONE SYNTHESIS AND RECYCLING%REACTOME DATABASE ID RELEASE 74%174403	Glutathione synthesis and recycling	GGCT	GCLC	CHAC1	GCLM	GGT5	GGT7	OPLAH	GGT6	CHAC2	GGT1	CNDP2	GSS	
P75NTR REGULATES AXONOGENESIS%REACTOME DATABASE ID RELEASE 74%193697	p75NTR regulates axonogenesis	RTN4	ARHGDIA	LINGO1	NGF	MCF2	NGFR	MAG	OMG	RHOA	
ASYMMETRIC LOCALIZATION OF PCP PROTEINS%REACTOME%R-HSA-4608870.1	Asymmetric localization of PCP proteins	PSMA6	FZD2	PSMA3	FZD5	PSMA4	FZD7	PSMA1	FZD4	PSMA2	PSME3	PSME4	PSME1	FZD8	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	PARD6A	SCRIB	SMURF2	PRICKLE1	SMURF1	VANGL2	DVL2	WNT5A	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	FZD1	FZD3	PSMA5	
FGFR3C LIGAND BINDING AND ACTIVATION%REACTOME DATABASE ID RELEASE 74%190372	FGFR3c ligand binding and activation	FGF4	FGF16	FGF9	FGF18	GALNT3	FGF20	FGF1	FGF23	FGF2	
EXTRACELLULAR MATRIX ORGANIZATION%REACTOME%R-HSA-1474244.2	Extracellular matrix organization	SPARC	AGRN	DMP1	MUSK	ITGAV	PDGFA	DDR1	PXDN	MATN1	ITGA2	MATN4	ITGA1	MATN3	DDR2	TNXB	DMD	DSPP	TNN	TNR	ITGA9	CD151	NID2	NTN4	LAMC3	ITGB4	HAPLN1	ASPN	LAMA4	NRXN1	LRP4	LAMB2	ITGAL	F11R	COLGALT2	PLOD3	PLOD2	ACTN1	PLOD1	ADAMTS2	ADAMTS3	COLGALT1	P3H2	P3H1	SDC2	PCOLCE	P3H3	PPIB	PCOLCE2	ADAMTS14	SERPINH1	CRTAP	P4HA1	P4HA2	P4HA3	TGFB2	TGFB3	LUM	FMOD	PTPRS	TGFB1	ITGB1	CEACAM1	CEACAM6	FN1	CEACAM8	ITGA5	BMP2	SERPINE1	PDGFB	ICAM2	ICAM3	ITGB5	TNC	ICAM4	ICAM5	LAMA2	ITGAE	LAMA1	ICAM1	COMP	IBSP	ITGAX	ITGB8	ITGB7	ITGB6	ITGA3	ITGAD	ITGA8	CASK	ITGA7	ITGA6	CD47	VTN	JAM2	JAM3	VCAM1	ITGA11	FBN1	NCAN	BGN	VCAN	ITGA2B	SDC4	FGF2	SDC3	PLEC	SDC1	FBN2	FBN3	BMP10	ELN	LOXL3	LTBP4	LOXL4	FBLN1	LTBP2	TTR	LTBP3	FBLN2	LTBP1	COL11A1	FBLN5	COL11A2	LOXL1	COL10A1	LOXL2	EFEMP2	COL28A1	EFEMP1	COL27A1	COL24A1	BMP7	GDF5	COL22A1	COL1A1	BMP4	COL3A1	MFAP5	COL1A2	MFAP4	COL2A1	LOX	COL4A2	MFAP1	COL5A1	MFAP3	COL4A1	MFAP2	COL6A2	COL4A4	COL7A1	COL5A3	COL4A3	COL5A2	COL6A1	COL20A1	COL8A2	COL4A6	COL21A1	COL6A3	COL4A5	COL8A1	COL6A6	COL6A5	PRSS1	COL16A1	COL12A1	ITGB3	CAPN15	CAPN8	CAPN9	CAPN6	CAPNS1	CAPN7	CDH1	CAPNS2	BSG	CAPN5	CAPN2	CAPN3	CAPN1	PRSS2	CAST	PHYKPL	CTRB2	COL23A1	CTRB1	ADAM10	HSPG2	BCAN	ADAM17	ADAM15	OPTC	ADAM9	ADAM8	COL17A1	COL13A1	HTRA1	PSEN1	KLK2	NID1	KLK7	ADAMTS16	SCUBE3	NCAM1	NCSTN	SCUBE1	ADAMTS18	A2M	ELANE	BMP1	COL9A1	COL9A3	COL9A2	COL18A1	COL14A1	LAMC2	LAMC1	CTSV	CTSS	MMP20	ADAMTS4	ADAMTS5	MMP25	MMP24	ITGA10	ADAMTS1	CTSL	CASP3	CTSK	TIMP2	CTSG	TIMP1	TPSAB1	ADAMTS8	CTSD	ADAMTS9	CTSB	KDR	MMP7	MMP1	COL25A1	MMP2	MMP3	MMP8	MMP9	MMP10	DCN	MMP12	MMP11	MMP14	MMP13	MMP16	MMP15	MMP17	MMP19	CD44	LAMA5	COL15A1	TMPRSS6	LAMA3	PLG	FURIN	COL19A1	SPOCK3	SPP1	COL26A1	LAMB3	CMA1	LAMB1	CAPN13	CAPN14	PRKCA	CAPN11	CAPN12	ITGA4	CAPN10	TLL2	TLL1	KLKB1	THBS1	P4HB	DAG1	TRAPPC4	FGB	FGA	FGG	ITGAM	ITGB2	ADAM19	SH3PXD2A	ADAM12	
SUMOYLATION OF DNA METHYLATION PROTEINS%REACTOME%R-HSA-4655427.3	SUMOylation of DNA methylation proteins	PHC2	DNMT3A	PHC1	PCGF2	PHC3	RNF2	BMI1	DNMT1	SUMO1	DNMT3B	UBE2I	CBX8	CBX4	RING1	CBX2	
LAMININ INTERACTIONS%REACTOME DATABASE ID RELEASE 74%3000157	Laminin interactions	LAMB3	NID1	LAMB2	LAMB1	LAMA2	LAMA1	ITGAV	COL18A1	ITGA3	LAMC2	ITGA2	LAMC1	ITGA7	ITGA1	ITGA6	ITGB1	HSPG2	LAMA5	LAMA3	NID2	LAMC3	ITGB4	LAMA4	
CHROMOSOME MAINTENANCE%REACTOME%R-HSA-73886.2	Chromosome Maintenance	HIST2H2AC	H2AFJ	NOP10	H2AFZ	H2AFX	H2AFV	CCNA2	CCNA1	HIST2H2BE	ITGB3BP	SMARCA5	HIST4H4	CENPA	CENPC	HIST1H2BN	CENPT	HIST1H2BM	CENPU	RTEL1	HIST1H2BO	APITD1	HIST1H2BJ	CENPH	HIST1H2BI	CENPI	HIST1H2BL	CENPK	CENPL	HIST1H2BK	CENPM	CENPN	HIST2H4A	CENPO	HIST2H4B	CENPP	BLM	CENPQ	RPA1	RPA2	CDK2	HIST3H3	WRAP53	RPA3	PRIM2	DSCC1	PRIM1	CHTF18	WRN	CHTF8	OBFC1	CTC1	POLA1	POLA2	TEN1	DNA2	DAXX	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	RFC5	POLR2I	RFC3	POLR2J	FEN1	PCNA	POLR2K	RFC4	POLR2L	RFC1	LIG1	RFC2	POLD3	POLD4	POLD1	POLD2	RUVBL1	HJURP	RUVBL2	OIP5	STRA13	SHQ1	PIF1	TERT	NPM1	RSF1	MIS18BP1	ATRX	CENPW	MIS18A	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	TINF2	TERF1	TERF2	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	GAR1	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	ANKRD28	RBBP4	RBBP7	H3F3B	HIST1H4K	HIST1H4L	H3F3A	CASC5	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	DKC1	HIST1H4D	HIST1H4E	PPP6C	NHP2	HIST1H4F	HIST2H2AA3	HIST2H2AA4	PPP6R3	
P75NTR SIGNALS VIA NF-KB%REACTOME DATABASE ID RELEASE 74%193639	p75NTR signals via NF-kB	NFKB1	RPS27A	SQSTM1	RIPK2	NFKBIA	NGF	NGFR	TRAF6	UBA52	IRAK1	IKBKB	RELA	MYD88	PRKCI	UBB	UBC	
TOLL LIKE RECEPTOR 4 (TLR4) CASCADE%REACTOME%R-HSA-166016.2	Toll Like Receptor 4 (TLR4) Cascade	RIPK3	RIPK2	IRAK3	IRAK4	FOS	CREB1	TIRAP	DNM1	UBE2D1	TBK1	DUSP4	DNM2	TLR1	IRF3	DNM3	TRAF3	IRF7	UBA52	PELI1	BPI	TLR6	DUSP6	BIRC2	CUL1	DUSP7	TLR2	BIRC3	UBB	PELI3	PELI2	NOD1	NOD2	UBC	TANK	MAPK9	MAPK8	MAPK7	RPS27A	MAP3K1	S100B	PPP2CA	MAPK10	TNIP2	PPP2CB	SAA1	PTPN4	MAPK1	PLCG2	MAP2K1	PPP2R5D	IKBKB	ECSIT	IKBKG	RPS6KA3	MAP3K7	CHUK	RPS6KA2	RPS6KA1	MAPK3	UBE2D2	PTPN11	TRAF6	UBE2V1	RELA	UBE2N	TAB3	TAB2	TAB1	MAPKAPK2	IRAK2	NFKB1	NFKBIA	NFKBIB	MAPK14	MAPK11	PPP2R1B	BTK	TICAM2	LY96	TICAM1	CASP8	RIPK1	CD14	FADD	TLR4	ATF1	APP	ATF2	UBE2D3	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	CD180	MAP3K8	VRK3	SIGIRR	PPP2R1A	MAPKAPK3	AGER	BTRC	SOCS1	IRAK1	S100A12	MAP2K7	MAP2K6	JUN	SKP1	LY86	NFKB2	MYD88	ITGAM	ITGB2	FBXW11	HMGB1	NKIRAS1	NKIRAS2	LBP	CD36	RPS6KA5	IKBKE	DUSP3	
OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS%REACTOME%R-HSA-389397.1	Orexin and neuropeptides FF and QRFP bind to their respective receptors	NPFFR2	NPFFR1	NPFF	QRFPR	HCRT	QRFP	HCRTR2	HCRTR1	
IRF3-MEDIATED INDUCTION OF TYPE I IFN%REACTOME%R-HSA-3270619.1	IRF3-mediated induction of type I IFN	TBK1	IRF3	NLRP4	DTX4	MRE11A	TMEM173	PRKDC	XRCC6	XRCC5	TREX1	NLRC3	DDX41	IFI16	
NUCLEAR ENVELOPE (NE) REASSEMBLY%REACTOME%R-HSA-2995410.5	Nuclear Envelope (NE) Reassembly	LBR	LMNB1	TUBA4A	AHCTF1	NUP62	CHMP2B	EMD	CHMP2A	NDC1	CHMP4C	SEC13	CHMP4B	NUP133	CHMP3	RANGAP1	CHMP4A	CHMP6	CHMP7	RCC1	TNPO1	NUP54	CCNB2	CCNB1	TUBA4B	TUBAL3	PPP2CA	KPNB1	NUP43	TUBB4B	TUBA8	TUBB4A	NUP35	CDK1	NUP37	IST1	SPAST	RAN	CC2D1B	NUP107	SUMO1	NUP188	UBE2I	BANF1	TUBB8P12	TUBB8	TUBA3E	TUBA1C	VRK1	TUBB6	TUBA1B	LEMD3	TUBB3	LEMD2	TUBB1	NUP93	ANKLE2	PPP2R2A	SIRT2	TUBB2B	TUBB2A	NUP205	POM121	NUP160	NUP85	TUBA1A	PPP2R1A	NUP155	VPS4A	
CHL1 INTERACTIONS%REACTOME%R-HSA-447041.1	CHL1 interactions	NRP1	CNTN6	ITGA2	ITGA1	CHL1	ITGB1	ANK1	ITGA10	HSPA8	
MRNA EDITING%REACTOME%R-HSA-75072.3	mRNA Editing	ADAR	ADARB1	APOBEC1	APOBEC3C	APOBEC2	APOBEC4	APOBEC3H	A1CF	APOBEC3A	APOBEC3B	
MEIOTIC SYNAPSIS%REACTOME DATABASE ID RELEASE 74%1221632	Meiotic synapsis	LMNB1	STAG1	HIST2H2AC	STAG2	H2AFJ	H2AFZ	H2AFX	H2AFV	SMC1A	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	BRCA1	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST3H3	UBE2I	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	SYCP2	HIST1H2AJ	SYCP1	ATR	SYNE2	TINF2	SYNE1	TERF1	SUN2	TERF2	SUN1	TEX12	POT1	SMC1B	TERF2IP	HIST1H2BF	SYCE3	ACD	HIST1H2BE	SYCE2	HIST1H2BH	SYCE1	HIST1H2BG	REC8	STAG3	HIST1H2BB	SYCP3	HIST1H2BA	HIST1H2BD	HIST1H2BC	HSPA2	H2AFB1	HIST1H4K	HIST1H4L	FKBP6	SMC3	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	RAD21	
UNCOATING OF THE INFLUENZA VIRION%REACTOME%R-HSA-168336.3	Uncoating of the Influenza Virion	
DEFECTIVE ABCA1 CAUSES TGD%REACTOME%R-HSA-5682113.3	Defective ABCA1 causes TGD	ABCA1	APOA1	
GENE EXPRESSION (TRANSCRIPTION)%REACTOME DATABASE ID RELEASE 74%74160	Gene expression (Transcription)	ABCA6	TBL1X	SUZ12	CDK5R1	TBL1XR1	SMAD4	PIWIL2	TDRKH	PIWIL1	PIWIL4	DDX4	HENMT1	POLR2A	POLR2B	POLR2C	ASZ1	POLR2D	MAEL	POLR2E	POLR2F	MOV10L1	POLR2G	POLR2H	POLR2I	POLR2J	MYBL1	POLR2K	POLR2L	TDRD9	TDRD6	TDRD1	TDRD12	DEK	FKBP6	BLK	ELF1	ELF2	PAX5	TFAM	TFB2M	YWHAB	POLRMT	YWHAZ	MAPK14	MAPK11	ACTB	LSM10	LSM11	INTS1	INTS3	INTS2	INTS5	INTS4	INTS7	INTS6	INTS9	BGLAP	INTS8	INTS12	INTS10	ICE1	ICE2	SSU72	NABP2	NABP1	TAF8	ELL2	ELL3	RBX1	ZC3H8	RPRD2	RPAP2	ASUN	VWA9	CPSF3L	RPRD1B	RPRD1A	POU2F2	TGFA	GLI3	GLI2	GRIN2B	ITCH	SAP130	SAP30BP	BIRC5	DNMT1	BAZ2A	SMARCA5	DNMT3B	AURKB	KIT	CSF2	ITGA2B	GPI	APAF1	NEDD4L	IL2	SMURF2	SMURF1	IL3	SMAD7	STUB1	PML	CCND2	RFC5	RFC3	PCNA	RFC4	RFC2	PPP2R5C	MET	CAMK2B	CAMK2D	CDKN1A	CDKN1B	PHF20	CAMK2G	CHEK2	PTPN11	CHEK1	ZNF385A	PCBP4	MDM2	IL2RA	MDM4	BTG2	KRAS	TNKS1BP1	CNOT6L	PRMT1	CDC25C	RBL2	RBL1	PLAGL1	E2F4	E2F7	E2F8	PLK3	NPM1	GADD45A	ARID3A	CNOT10	CNOT4	CNOT7	RGCC	CNOT1	CNOT11	CNOT2	CNOT3	CNOT8	PTRF	ATF2	UBE2D3	MEF2C	ZNF17	ZNF287	ZNF18	RBFOX1	ZNF285	ZNF19	IRAK1	ZNF282	ZNF10	ZNF12	MAP2K6	ZNF14	JUN	AR	CLDN5	ZNF28	ZNF274	ZNF273	ZNF20	ZNF23	ZNF25	USP2	ZNF26	ZNF268	PPARGC1B	ZNF267	ZNF266	ZNF264	ZNF263	NR2F1	ZNF34	NR0B2	NR2F6	FOS	ZNF30	ZNF257	BCL2L11	ZNF256	ZNF496	ZNF254	ZNF253	ZNF493	ZNF492	ZNF250	UCMA	ZNF490	ZNF43	TNFRSF10D	ZNF45	HEY1	ZNF41	HEY2	CTLA4	ZNF248	ZNF486	ZNF485	ZNF484	CASP10	ZNF483	ACTL6B	RING1	CASP2	ZNF480	ACTL6A	SIRT3	ZNF479	ZNF235	ZNF234	ZNF233	PPARD	ZNF473	PTPN4	ZNF230	SERPINB13	ZNF471	ZNF470	HTT	ZNF227	ZNF468	ZNF226	ZNF225	ZNF224	ZNF223	ZNF222	MEN1	ZNF461	ZNF460	USP9X	ZNF77	ZNF79	SKI	ZNF70	ZNF71	ZNF74	AGRP	ZNF699	TFAP2A	ZNF215	TFAP2B	ZNF214	WWOX	ZNF697	TFAP2C	ZNF213	TFAP2D	ZNF696	TFAP2E	ZNF212	CITED1	ZNF454	CITED2	MTERF1	ZNF211	CITED4	ZNF692	YEATS4	ZNF691	RORC	MT-CO1	RORA	RORB	CTGF	TACO1	ZNF208	ZNF205	COX6A1	ZNF689	ZNF688	ZNF446	ZNF445	COX6B1	ZNF202	COX7A2L	SCO1	ZNF443	SCO2	ZNF200	ZNF684	MT-CO2	ZNF442	ZNF441	MT-CO3	ZNF682	ZNF440	ZNF681	COX19	ZNF680	COX16	ZFP69B	FOXP3	MAF	ZNF439	COX18	ZNF679	ZNF678	COX11	ZNF436	COX14	ZNF677	ZNF676	ZNF675	ZNF433	PVALB	ZNF432	SURF1	ZNF431	KMT2E	ZNF430	ZNF671	ZNF670	DLX5	DLX6	CYCS	KMT2B	FOXO6	FOXO4	ATXN3	COX20	GTF2A1	ZKSCAN7	COX7B	GTF2A2	MOBP	COX4I1	GTF2B	ZNF429	TAF9	ZKSCAN8	TAF1L	ZNF669	AK6	ZKSCAN3	COX7C	GTF2E1	ZNF668	GTF2E2	ZNF426	COX8A	TAF7L	ZKSCAN5	TAF9B	ZNF667	TAF15	ZNF425	TAF12	ZKSCAN4	TAF13	ZNF665	TAF10	ZNF664	TAF11	SOCS4	TAF4B	ZKSCAN1	TAF7	ZNF662	TAF6	ZNF660	TAF5	DNMT3A	BDNF	TAF4	FBXO32	TAF3	ZNF419	TAF2	SP1	TAF1	ZNF418	ZNF417	ZNF658	ZNF416	ZNF415	ZNF655	SP7	ITGAL	ZNF649	YAF2	ZNF641	NKX3-2	COX5B	TRIM63	COX5A	TNFRSF18	HAND2	PPM1D	ZNF627	ZNF626	ZNF625	ZNF624	ZNF621	NDUFA4	ZNF620	E2F6	ZNF860	MGA	COX6C	TBX5	LRPPRC	PINK1	ZNF619	SST	ZNF616	ZNF615	ZNF614	ZNF613	ZNF611	ZNF610	TRIM33	SMARCB1	UXT	LGALS3	ZNF729	TRIM28	ZNF727	ZNF726	EPC1	ZNF721	ZNF720	SMARCC1	SMARCC2	ZFP1	ZFP2	ZNF716	ZNF713	ZNF711	ZNF710	ZNF324B	L3MBTL2	FOXG1	ZNF709	ZNF708	ZNF707	ZNF706	ZNF704	ZNF703	ZNF701	ZNF700	HIVEP3	SMARCA2	ITGBL1	MSTN	BMI1	HNF4A	SREBF1	PBRM1	SATB2	RXRB	ZFP14	ZNF585B	RXRG	ZNF585A	CCNG2	ZFP28	PRDM7	NPPA	ARID2	G6PC	MSX2	MYBBP1A	ZNF99	UHRF1	ZNF92	SUV39H1	GPRIN1	ZFHX3	PHF19	AUTS2	RRP8	VDR	PHF1	CAV1	JARID2	BMP2	TET2	DPY30	TET1	TGIF1	AEBP2	RBM14	TET3	TGIF2	MTF2	CAT	IPO8	CAMK2A	RETN	DNMT3L	LEF1	TCF7	RNF2	RRM2	ZNF804B	ZNF175	SERPINE1	ZSCAN32	ZNF169	JUNB	RNF111	ZNF705G	ZNF705D	MYB	ZNF160	ZNF705A	ZSCAN25	ZNF157	ZNF398	ZNF155	TCF7L2	ZNF154	TP53	ZNF394	TCF7L1	NKX2-5	ZFPM1	NR2C2AP	PHC2	ZNF141	ZNF383	GATA4	PHC1	GATA3	FOXO1	ZNF140	GATA2	ZNF382	GATA1	SETD1B	SETD1A	NR1D2	TNRC6C	MOV10	CDC7	ABL1	AGO3	NR1D1	AGO4	NFE2	PHC3	ZNF37A	CBX5	AGO1	ZNF138	PRDX2	ZNF136	AGO2	PRDX1	ZNF135	SOD2	ZNF133	BTG1	RSPO3	CDK5	CTNNB1	ZNF124	TEAD2	TNRC6A	ZIK1	TNRC6B	TEAD3	TEAD4	BRD2	ZNF724P	ZNF599	ZNF114	ZNF597	ZNF596	ZNF112	ZNF350	ZNF589	ZNF347	ZNF587	FOXO3	ZIM2	ZNF586	ZIM3	ZNF101	ZNF343	ZNF100	SIN3A	ZNF584	ZNF583	ZNF582	PCGF6	PCGF5	WWP1	ZNF33B	ZNF33A	RYBP	ZNF337	BRIP1	ZNF577	HDAC2	EXO1	ZNF334	HDAC1	ZNF333	TOPBP1	ATRIP	ZNF573	BARD1	ZNF331	RMI2	ZNF571	RMI1	WRN	ZNF570	HUS1	ZFP30	ZNF569	ZNF568	ZNF567	RAD17	ZNF566	RAD1	ZNF324	ZNF565	RAD9B	DNA2	RHNO1	ZFP37	ZNF564	ATR	ZNF563	RAD9A	ZNF562	ZNF320	ZNF561	ZNF560	NFATC2	NRBP1	ZNF559	ZNF317	ZNF558	ZNF557	PGR	ZNF799	ZNF556	ERBB2	ZNF555	ZNF554	ATM	ZNF311	ZNF552	FKBP5	MYL9	ZNF551	ZNF793	ZNF550	PTPN1	ZNF792	CSF1R	ZNF791	ZNF790	KRBA1	KRBOX4	ZNF549	YWHAQ	ZNF548	ZNF547	SFN	ZNF546	BID	ZNF304	YWHAH	ZNF544	ZNF302	ZNF786	ZNF543	ZNF785	SKIL	ZNF300	ZNF540	ESRRA	STAT1	ZNF782	ESRRB	ESRRG	ZFP69	PHAX	ZNF778	ZNF777	ZNF776	ZNF775	ZNF774	ZNF773	ZNF530	ZNF772	ZNF771	ZNF770	SIN3B	ZNF529	ZNF528	ZNF764	ZNF521	LBR	MAPK3	CR1	ZNF75D	ZFP90	ZNF75A	ZNF519	ZNF517	ZNF514	ZNF510	ZNF750	HDAC4	SMARCD1	HDAC5	SMARCD2	HDAC8	HDAC9	HDAC7	EGFR	ZNF749	ZNF506	ZNF747	ZNF746	ZNF500	ZNF740	SMARCE1	ZNF738	ZNF737	ZNF736	ZNF735	ZNF732	ZNF730	HDAC10	HDAC11	TXNIP	ZNF607	ZNF606	ZNF605	TXN	ZNF600	SOX9	RUNX3	VEGFA	CGA	ZNF839	HKR1	TWIST2	TWIST1	OCLN	PRMT6	ZNF2	ZNF3	NPY	TJP1	ZNF354A	ZNF354C	ZNF354B	LMO1	LMO2	ATP1B4	LIFR	KCTD6	CBX8	SMAD1	CBX6	CBX4	CBX2	SMAD6	ESR2	NR4A2	APOE	NR4A1	NR4A3	THRB	THRA	SLC2A3	NR2E1	OPRM1	NR1H2	ARID1A	ARID1B	ZNF197	ZNF195	NR2C2	THBS1	NR2C1	ZNF189	ZNF286A	ZNF184	ZNF180	OPRK1	CASP1	YWHAE	POMC	PPP2R1A	PRKACA	YWHAG	SKP1	HSP90AA1	BCDIN3D	XPO5	DROSHA	DGCR8	UBA52	CUL1	AURKA	CCNB1	CPSF7	UBB	CPSF1	CPSF3	CSTF3	CSTF2	UBC	CPSF2	CSTF2T	BRCA1	WDR33	NUDT21	RPS27A	NBN	FIP1L1	CLP1	TOP3A	PCF11	PAPOLA	CSTF1	SYMPK	BLM	RBBP8	RPA1	RPA2	MRE11A	MLH1	CENPJ	CDK1	RAD50	RAD51	RPA3	MDC1	CCNK	CEBPB	TP53RK	EHMT1	NOC2L	GLS	TP53AIP1	PIP4K2A	IGFBP1	PIP4K2B	PIP4K2C	NFYA	TP63	NFYB	DAXX	NFYC	DDIT4	L3MBTL1	DDIT3	MEAF6	CDC73	NUAK1	TP53BP2	BANP	PRELID1	CRADD	TPX2	CDK12	CDK13	TP73	SETD9	CTR9	CHM	BBC3	WDR61	RTF1	ING5	ING2	AIFM2	PRMT5	LEO1	BRD1	DDB2	IL6	RAD51D	PLK2	SGK1	PMS2	BRD7	TIGAR	HIPK1	POU4F1	PAF1	POU4F2	HIPK2	TTC5	CCNG1	CCNT2	PRDM1	SESN3	SESN2	BNIP3L	USP7	G6PD	IGFBP3	MSH2	FANCD2	KAT6A	MAPKAPK5	NDRG1	SMYD2	PMAIP1	BCL2L14	ZNF420	FANCI	BRPF1	SLMO1	BRPF3	TNFRSF10C	FANCC	TP53I3	BCL6	JMY	PIN1	PPP1R13B	DYRK2	PTEN	TRIAP1	PIDD1	CASP6	PPP1R13L	GPX2	RABGGTB	RABGGTA	RRM2B	TMEM219	TMEM55B	RNF34	GLS2	NLRC4	TP53INP1	RNMT	RFFL	RNGTT	TXNRD1	SIRT1	CSNK2A1	SRC	CSNK2A2	HDAC6	BAX	NELFB	CSNK2B	SMAD2	SMAD3	TGFB1	PLD6	TDG	NOTCH2	MAML2	MAML1	RBPJ	DLL1	EP300	HES1	JAG1	CREB1	MAML3	MAMLD1	GRIA2	GRIN2A	CAMK4	GPAM	EIF4A3	CASC3	MAGOH	NCBP1	NCBP2	THOC1	THOC3	THOC2	THOC5	THOC7	CDC40	SRRM1	THOC6	DDX39A	DDX39B	SARNP	ZC3H11A	SRSF2	SRSF3	SRSF4	SRSF5	SRSF6	SRSF7	SLU7	SRSF9	FYTTD1	LUZP4	RBM8A	POLDIP3	SRSF1	U2AF1	U2AF1L4	U2AF2	DHX38	SRSF11	CHTOP	UPF3B	MAGOHB	RNPS1	GTF2F1	GTF2F2	CPSF4	YES1	PARP1	PABPN1	RAN	RB1	NUP107	NUP188	PPP2R1B	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	NUP214	NUP210	PRKCB	HIST1H2AJ	NUP93	HIST2H3A	INS	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	RRN3	NUP205	CCNH	POM121	EHMT2	H2AFB1	TSNAX	CHD4	CHD3	HIST1H3J	PRKRA	DICER1	AAAS	TTF1	TARBP2	TAF1D	ZNRD1	NUP160	TSN	MTA1	HIST1H3A	NUP85	RBBP4	TAF1B	TPR	TAF1C	HIST1H3F	HIST1H3G	TWISTNB	TAF1A	NUP88	UBTF	HIST1H3H	RBBP7	HIST1H3I	MTA2	HIST1H3B	MTA3	HIST1H3C	MBD3	HIST1H3D	CD3EAP	HIST1H3E	GTF2H1	NUP155	GTF2H2	AFF4	H3F3B	GTF2H3	MLLT1	GTF2H4	HIST1H4K	GATAD2B	MLLT3	HIST1H4L	SUPT6H	GTF2H5	GATAD2A	IWS1	EAF1	KAT2B	EAF2	H3F3A	CDK7	NUP153	KAT2A	H2BFS	ERCC3	POLR1A	HIST1H4A	SPI1	POLR1B	HIST1H4B	ERCC2	HIST1H4H	POLR1E	HIST1H4I	ERCC6	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	SETD8	NOP2	HIST2H2AC	H2AFJ	NUP62	UBE2D1	CDC23	CDC26	NDC1	CDC27	SEC13	NUP133	SKP2	ANAPC7	H2AFZ	UBE2E1	H2AFX	CCNA2	H2AFV	PPARGC1A	CCNA1	HIST2H2BE	CCNE2	CCNE1	HIST4H4	NUP50	ANAPC4	DDX21	ANAPC5	NUP54	EZH2	ANAPC1	HIST1H2BN	HIST1H2BM	MED16	ANAPC2	MED15	ANAPC15	HIST1H2BO	ANAPC16	HIST1H2BJ	MED17	ANAPC10	HIST1H2BI	MED12	ANAPC11	HIST1H2BL	MED14	FZR1	HIST1H2BK	MED13	PPP2CA	MED10	HIST2H4A	PPP2CB	HIST2H4B	MAPK1	UBE2C	NUP43	MED27	RAE1	MED26	UBE2S	RANBP2	CDC16	CDK2	NUP35	MED23	NUPL2	MED25	NUP37	MED24	MED20	PPARG	PPARA	YY1	KMT2D	IHH	KMT2A	KMT2C	MED30	MED31	CRH	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	AXIN1	E2F1	PSMA5	PSMA6	PSMA3	PSMA4	RQCD1	PSMA1	CCNC	PSMA2	PSME3	BAZ1B	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PRKCQ	PSMD13	NOTCH1	MAX	PSMB10	PSMA7	MYBL2	E2F5	RELA	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	GAMT	NFKB1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PCK1	PSMC1	PSMC2	WWTR1	SMARCA4	SNW1	KDM5B	HNF4G	HSPD1	SUMO1	PITX2	UBE2I	ATAD2	KCTD1	ESR1	KCTD15	NR5A1	YAP1	TNFRSF10B	RXRA	NOTCH3	NOTCH4	TNFRSF10A	PERP	FASLG	FAS	SOCS3	IFNG	CCND3	PRR5	PDPK1	MAPKAP1	ITGA5	MTOR	AKT2	GPS2	AKT3	MLST8	AKT1	RICTOR	STEAP3	GSK3B	CCND1	CDK4	TCF3	LDB1	CREBBP	EED	CTDP1	ELL	CCNT1	SUPT4H1	TCEB3	TCEB2	VENTX	TCEB1	CARM1	NELFA	GAD1	CDKN2B	NELFCD	GAD2	TCEB3C	TCEB3CL	SNRPD3	TCEB3B	NELFE	MYC	SUPT16H	SSRP1	SUPT5H	CDK9	TCEA1	SLBP	TCEB3CL2	MED1	MED8	MED4	MED6	MED7	SRRT	COL1A1	SF3B1	PRKAA1	PRKAA2	CBX3	MBD2	RARG	PRKAG1	PRKAG2	ASH2L	PRKAG3	RPTOR	STK11	SLC38A9	PRKAB2	TEAD1	TSC2	TCF12	TSC1	PRKAB1	PPM1A	NCOR2	SNRPG	NCOR1	RRAGA	TAL1	RRAGC	RARA	SNRPE	RRAGB	RARB	SNRPF	RHEB	RRAGD	LAMTOR2	CDK6	CDKN2A	LAMTOR1	LAMTOR4	SNRPB	LAMTOR3	LAMTOR5	PCGF2	GCK	CBFB	PLXNA4	CTSV	CDK8	GTF3C1	CNOT6	GTF3C2	GTF3C3	CRCP	GTF3C4	NFIX	GTF3C5	GTF3C6	CTSL	SNAPC5	CTSK	SNAPC1	SNAPC2	SNAPC3	WDR5	SNAPC4	ZNF143	POU2F1	BRF2	TBP	SSB	BRF1	POLR3GL	GTF3A	TRPC3	POLR3A	POLR3B	NFIA	POLR3C	NFIB	POLR3D	NFIC	POLR3E	POLR1C	MMP13	POLR3F	POLR3G	POLR3H	BDP1	POLR3K	TFDP1	TFDP2	SMARCD3	HDAC3	SPP1	RBBP5	ARID4B	NR3C1	ITGA4	KLF4	KAT5	SAP30	SOX2	SAP30L	SAP18	SUDS3	RUNX1	GP1BA	PF4	
TERMINATION OF O-GLYCAN BIOSYNTHESIS%REACTOME%R-HSA-977068.1	Termination of O-glycan biosynthesis	MUC3A	MUC5AC	MUC1	MUC7	MUC12	MUC13	MUC15	MUC20	ST3GAL4	MUC4	MUC21	MUC6	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	ST6GALNAC3	ST6GALNAC4	MUCL1	MUC17	ST6GALNAC2	MUC5B	
ACTIVATION OF G PROTEIN GATED POTASSIUM CHANNELS%REACTOME DATABASE ID RELEASE 74%1296041	Activation of G protein gated Potassium channels	KCNJ5	KCNJ6	GABBR1	KCNJ10	KCNJ12	KCNJ9	KCNJ15	GNG12	KCNJ16	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	GNGT1	GNGT2	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	KCNJ2	KCNJ3	KCNJ4	GABBR2	
DEFECTIVE SLC40A1 CAUSES HEMOCHROMATOSIS 4 (HFE4) (MACROPHAGES)%REACTOME DATABASE ID RELEASE 74%5619049	Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages)	CP	SLC40A1	
THE FATTY ACID CYCLING MODEL%REACTOME DATABASE ID RELEASE 74%167826	The fatty acid cycling model	SLC25A27	UCP3	UCP2	UCP1	SLC25A14	
PHASE II - CONJUGATION OF COMPOUNDS%REACTOME DATABASE ID RELEASE 74%156580	Phase II - Conjugation of compounds	CYP1A2	SLC26A2	SLC26A1	GGT7	GGT6	MGST3	MGST1	MGST2	PAPSS1	CHAC2	SULT1A1	GSTT2B	SULT1A4	SULT1A2	GSTM4	GSTM3	SULT2A1	GSTM2	GSTM1	SULT1B1	GSTM5	GSTO2	SULT1C2	HPGDS	SULT1C4	AKR1A1	SULT1E1	TPST2	GSTA5	TPST1	GLYATL3	GSTA4	GLYATL2	GSTZ1	GSTA3	GLYATL1	GSTA2	ACSM1	GSTA1	CNDP2	ACSM2A	ACSM5	SULT6B1	ACSM4	GSTT2	GSTT1	GLYAT	ESD	ACSM2B	GGCT	GCLC	NAT1	NAT2	GCLM	UGT1A9	PODXL2	OPLAH	SULT4A1	ABHD14B	IMPAD1	BPNT1	GSS	N6AMT1	MTRR	NNMT	AHCY	GSTP1	TPMT	GSTO1	MTR	MAT2B	MAT1A	AS3MT	MAT2A	SULT1A3	CHAC1	SLC35B3	SLC35B2	SLC35D1	GSTK1	COMT	GGT1	UGT1A4	GGT5	TRMT112	UGT2B10	UGT1A10	UGT2B11	UGT2B15	UGT2B17	UGT2B28	UGDH	ABHD10	UGP2	UGT1A5	UGT2A3	UGT3A2	UGT2B4	UGT3A1	UGT1A3	UGT1A8	UGT2B7	PAPSS2	UGT1A7	UGT1A6	UGT1A1	
GAP JUNCTION DEGRADATION%REACTOME DATABASE ID RELEASE 74%190873	Gap junction degradation	GJA1	DNM1	AP2M1	DNM2	CLTCL1	CLTC	CLTA	MYO6	DAB2	CLTB	
DEACTIVATION OF THE BETA-CATENIN TRANSACTIVATING COMPLEX%REACTOME%R-HSA-3769402.3	Deactivation of the beta-catenin transactivating complex	SOX3	SOX17	SRY	SOX6	RBBP5	SOX7	SOX4	BCL9L	TLE3	CTNNBIP1	SOX13	PYGO1	PYGO2	BCL9	UBA52	ASH2L	KMT2D	SOX2	XPO1	CTNNB1	UBB	YWHAZ	UBC	AKT2	TLE4	TLE2	RPS27A	TLE1	AKT1	SOX9	LEF1	BTRC	TCF7	MEN1	HDAC1	XIAP	APC	CTBP1	TCF7L2	CHD8	CBY1	TCF7L1	
SIGNALING BY HIGH-KINASE ACTIVITY BRAF MUTANTS%REACTOME%R-HSA-6802948.1	Signaling by high-kinase activity BRAF mutants	MAPK3	RAF1	CSK	SRC	RAP1B	RAP1A	MARK3	YWHAB	NRAS	FN1	CNKSR2	HRAS	APBB1IP	CNKSR1	ITGB3	ARRB1	ARAF	ARRB2	MAPK1	FGB	FGA	ITGA2B	VWF	PEBP1	KSR1	FGG	TLN1	KSR2	IQGAP1	BRAF	MAP2K1	MAP2K2	VCL	
MISSPLICED GSK3BETA MUTANTS STABILIZE BETA-CATENIN%REACTOME%R-HSA-5339716.2	Misspliced GSK3beta mutants stabilize beta-catenin	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	CTNNB1	PPP2R1B	AMER1	AXIN1	APC	
DEFECTIVE ABCB6 CAUSES MCOPCB7%REACTOME DATABASE ID RELEASE 74%5683371	Defective ABCB6 causes MCOPCB7	ABCB6	
LXRS REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE%REACTOME DATABASE ID RELEASE 74%9031525	LXRs regulate gene expression to limit cholesterol uptake	RXRA	RXRB	NR1H2	MYLIP	NR1H3	
INHIBITION OF NITRIC OXIDE PRODUCTION%REACTOME%R-HSA-9636249.1	Inhibition of nitric oxide production	KPNA1	KPNB1	NOS2	
ACTIVATION OF PKB%REACTOME%R-HSA-165158.3	Activation of PKB	THEM4	TRIB3	PDPK1	AKT2	
SPHINGOLIPID DE NOVO BIOSYNTHESIS%REACTOME%R-HSA-1660661.7	Sphingolipid de novo biosynthesis	ORMDL2	ORMDL3	OSBP	SPTSSB	SPTSSA	KDSR	CERS3	CERS4	CERS5	CERS6	SPHK2	SPNS2	ORMDL1	SGPP2	SGPP1	VAPA	ACER2	ACER1	FA2H	PRKD3	VAPB	PPAP2B	ACER3	SPHK1	PPAP2A	PRKD2	DEGS1	PRKD1	DEGS2	CSNK1G2	CERS1	CERS2	SAMD8	PPM1L	PPAP2C	SGMS2	ALDH3B2	SGPL1	SPTLC1	SPTLC2	SPTLC3	ALDH3B1	
MATURATION OF REPLICASE PROTEINS%REACTOME DATABASE ID RELEASE 74%9684325	Maturation of replicase proteins	
FORMATION OF TC-NER PRE-INCISION COMPLEX%REACTOME%R-HSA-6781823.1	Formation of TC-NER Pre-Incision Complex	UBA52	COPS7B	COPS7A	UBB	UBC	RPS27A	HMGN1	AQR	ZNF830	UVSSA	ERCC8	TCEA1	PRPF19	GPS1	XAB2	CCNH	XPA	CUL4A	DDB1	POLR2A	POLR2B	POLR2C	CUL4B	PPIE	POLR2D	POLR2E	RBX1	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	COPS4	GTF2H3	COPS3	GTF2H4	COPS6	ISY1	GTF2H5	COPS5	USP7	CDK7	COPS2	ERCC3	COPS8	ERCC2	ERCC6	EP300	MNAT1	
MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS%REACTOME%R-HSA-9022699.1	MECP2 regulates neuronal receptors and channels	GPRIN1	CREB1	SLC2A3	PTPN4	TRPC3	OPRM1	SIN3A	GRIA2	OPRK1	HDAC2	HDAC1	FKBP5	GRIN2B	PTPN1	GRIN2A	MET	
RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING%REACTOME DATABASE ID RELEASE 74%8939247	RUNX1 regulates transcription of genes involved in interleukin signaling	IL3	CBFB	ELF1	LIFR	RUNX1	
EPH-EPHRIN SIGNALING%REACTOME DATABASE ID RELEASE 74%2682334	EPH-Ephrin signaling	PAK3	PAK2	EPHB2	NCSTN	EPHB1	DNM1	EPHB4	NGEF	EPHB3	EPHA5	EPHA4	EPHA7	EPHA6	EPHA8	LYN	HRAS	EPHA1	EPHA3	EPHA2	AP2A1	EPHA10	SDC2	AP2A2	KALRN	GRIN1	AP2M1	MMP2	MMP9	CLTC	CLTA	RAC1	YES1	ARPC1B	ARPC1A	WASL	GIT1	ACTB	ACTG1	ACTR3	VAV3	ACTR2	CDC42	VAV2	ARHGEF7	AP2S1	ROCK1	EFNA5	ARPC4	ROCK2	EFNA4	LIMK2	ARPC5	EFNB2	LIMK1	SDCBP	RHOA	EFNB1	MYL12B	EFNB3	AP2B1	ARPC2	CLTB	ARPC3	EFNA1	MYL6	EFNA3	MYH9	EFNA2	MYH14	MYH11	MYH10	MYL9	CLTCL1	TIAM1	ARHGEF28	FYN	NCK2	MYL12A	PSEN2	ADAM10	CFL1	APH1A	ITSN1	RASA1	APH1B	GRIN2B	PTK2	PAK1	PSENEN	PSEN1	
CIRCADIAN CLOCK%REACTOME DATABASE ID RELEASE 74%400253	Circadian Clock	CSNK1E	CREB1	TGS1	UBA52	NR1D1	PPARGC1A	CUL1	NRIP1	UBB	UBC	CARM1	RPS27A	TBL1X	FBXL3	MED1	PPP1CC	NCOA1	PPARA	NCOA2	NCOA6	SMARCD3	HDAC3	SIRT1	MEF2D	CRTC2	RXRA	CRTC3	CRTC1	NR3C1	TBL1XR1	RORA	SREBF1	PPP1CA	AVP	ATF2	NCOR1	CPT1A	MEF2C	CLOCK	PPP1CB	NPAS2	NAMPT	BHLHE41	BTRC	RBM4	DBP	CCRN4L	KLF15	SERPINE1	CRY2	HELZ2	SKP1	CRY1	SIK1	ARNTL2	ARNTL	F7	RAI1	NFIL3	CHD9	PER2	PER1	CREBBP	BHLHE40	EP300	HIF1A	CSNK1D	
ASPARTATE AND ASPARAGINE METABOLISM%REACTOME%R-HSA-8963693.1	Aspartate and asparagine metabolism	GADL1	GOT1	GOT2	NAALAD2	SLC25A12	ASPG	FOLH1	ASNS	NAT8L	SLC25A13	ASPA	
SIGNALING BY MET%REACTOME DATABASE ID RELEASE 74%6806834	Signaling by MET	SH3KBP1	LAMB2	PTPRJ	LAMA2	STAM	SPINT2	LAMA1	TNS4	HGS	PTPN11	TNS3	HGFAC	SPINT1	HPN	LRIG1	UBA52	EPS15	RAB4B	SH3GL1	ITGA3	RANBP10	LAMC2	LAMC1	GAB1	STAM2	CBL	NRAS	SOS1	HRAS	UBB	UBC	RPS27A	RANBP9	DOCK7	MUC20	RAC1	CRKL	RAPGEF1	LAMA5	LAMA3	HGF	ARF6	LAMB3	LAMB1	GGA3	SRC	RAP1B	RAP1A	USP8	ITGB1	SH3GL2	PTPN2	PIK3R1	PTPN1	PIK3CA	CRK	RAB4A	SH3GL3	STAT3	ITGA2	PTK2	LAMC3	MET	LAMA4	
ASSEMBLY OF THE SARS-COV-1 REPLICATION-TRANSCRIPTION COMPLEX (RTC)%REACTOME%R-HSA-9683439.2	Assembly of the SARS-CoV-1 Replication-Transcription Complex (RTC)	
TCF DEPENDENT SIGNALING IN RESPONSE TO WNT%REACTOME%R-HSA-201681.1	TCF dependent signaling in response to WNT	CSNK1E	HIST2H2AC	H2AFJ	UBA52	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	UBB	HIST1H2BN	HIST1H2BM	HIST1H2BO	UBC	HIST1H2BJ	HIST1H2BI	HIST1H2BL	RPS27A	HIST1H2BK	PPP2CA	HIST2H4A	PPP2CB	HIST2H4B	HIST3H3	MEN1	PIP5K1B	USP8	CDC73	KMT2D	LEO1	WNT9A	PSMD8	WNT8A	WNT8B	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	AMER1	WNT1	PSMD1	AXIN1	WNT3	APC	WNT4	FZD1	PSMA5	PSMA6	PSMA3	WNT3A	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	FZD8	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	XPO1	PSMA8	PSMB6	TERT	PSMB7	PSMB4	PSMB5	YWHAZ	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	SMARCA4	CSNK2A1	CSNK2A2	CSNK2B	AKT2	TLE4	TLE2	TLE1	AKT1	RBX1	CAV1	WNT5A	GSK3B	LEF1	TCF7	RNF146	CREBBP	EP300	CTBP1	TCF7L2	CHD8	CBY1	TCF7L1	SOX3	FZD2	SOX17	FZD5	SRY	SOX6	FZD4	SOX7	FZD6	SOX4	CSNK1A1	BCL9L	TLE3	CTNNBIP1	SOX13	PYGO1	PYGO2	BCL9	RSPO3	CTNNB1	MYC	TNKS2	TNKS	HDAC1	XIAP	CUL3	ASH2L	SMURF2	CSNK1G2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	RUVBL1	SOX9	RUNX3	TRRAP	FRAT1	FRAT2	DKK1	DKK2	DKK4	SFRP1	SFRP2	HECW1	CCDC88C	RSPO2	RSPO1	PPP2R1B	RSPO4	KREMEN1	HIST1H2AE	KREMEN2	HIST1H2AD	WIF1	HIST3H2BB	LGR6	LGR5	HIST1H2AC	LGR4	HIST1H2AB	RNF43	KLHL12	USP34	SOST	HIST1H2AJ	DACT1	AXIN2	RBBP5	LRP5	LRP6	ZNRF3	HIST2H3A	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	DVL1	SOX2	DVL2	HIST1H2BD	HIST1H2BC	DVL3	H2AFB1	HIST1H3J	HIST1H3A	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	PPP2R1A	HIST1H3C	HIST1H3D	HIST1H3E	BTRC	H3F3B	HIST1H4K	HIST1H4L	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
DEFECTIVE GAMMA-CARBOXYLATION OF F9%REACTOME DATABASE ID RELEASE 74%9673240	Defective gamma-carboxylation of F9	F9	GGCX	
REGULATION OF CORTICAL DENDRITE BRANCHING%REACTOME%R-HSA-8985801.1	Regulation of cortical dendrite branching	ROBO1	SLIT1	NCK2	ROBO2	
UNBLOCKING OF NMDA RECEPTORS, GLUTAMATE BINDING AND ACTIVATION%REACTOME%R-HSA-438066.3	Unblocking of NMDA receptors, glutamate binding and activation	GRIN1	NEFL	CAMK2G	DLG1	DLG3	ACTN2	DLG4	CAMK2A	GRIA1	GRIA2	DLG2	GRIN2B	GRIN2A	GRIN2D	LRRC7	GRIA3	GRIA4	CAMK2B	GRIN2C	CAMK2D	
DEFECTIVE CHSY1 CAUSES TPBS%REACTOME DATABASE ID RELEASE 74%3595177	Defective CHSY1 causes TPBS	BCAN	NCAN	CHSY1	BGN	VCAN	DCN	CSPG5	CSPG4	
DEFECTIVE LMBRD1 CAUSES METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE CBLF%REACTOME DATABASE ID RELEASE 74%3359458	Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF	LMBRD1	
DEFECTIVE SLC27A4 CAUSES ICHTHYOSIS PREMATURITY SYNDROME (IPS)%REACTOME DATABASE ID RELEASE 74%5619108	Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS)	SLC27A4	
ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS%REACTOME DATABASE ID RELEASE 74%5617472	Activation of anterior HOX genes in hindbrain development during early embryogenesis	PKNOX1	HIST2H2AC	H2AFJ	AJUBA	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	PBX1	EZH2	HIST1H2BN	CTCF	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	SUZ12	HIST2H4A	HOXA3	HIST2H4B	HOXA2	HOXA1	HOXA4	HOXB4	HOXB3	HOXB2	HOXB1	HOXD1	HOXC4	YY1	PIAS2	HOXD4	HOXD3	RARG	ASH2L	KMT2D	KMT2C	KDM6A	PAX6	POLR2A	POLR2B	NCOR1	POLR2C	POLR2D	RARA	RARB	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	PCGF2	ZNF335	MEIS1	RQCD1	CNOT6	MAFB	PAXIP1	PAGR1	WDR5	EGR2	NCOA6	HIST1H2AE	NCOA3	HIST1H2AD	HDAC3	HIST3H2BB	HIST1H2AC	HIST1H2AB	RXRA	HIST1H2AJ	RBBP5	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	RBBP4	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	RBBP7	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	JUN	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	CREBBP	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	EED	HIST2H2AA3	HIST2H2AA4	
SYNTHESIS OF DIPHTHAMIDE-EEF2%REACTOME%R-HSA-5358493.1	Synthesis of diphthamide-EEF2	DPH1	DPH2	DPH3	DPH5	EEF2	DPH6	DPH7	
HOST INTERACTIONS OF HIV FACTORS%REACTOME%R-HSA-162909.1	Host Interactions of HIV factors	PAK2	NUP62	NDC1	ATP6V1H	SEC13	NUP133	UBA52	RANGAP1	NUP50	NUP54	UBB	HCK	CCNT1	UBC	TCEB2	TCEB1	RPS27A	CDK9	NUP43	RAE1	RANBP2	ARF1	RAC1	NUP35	NUPL2	NUP37	DOCK2	SLC25A5	SLC25A4	SLC25A6	PPIA	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	RCC1	PSMA7	XPO1	PSMA8	PSMB6	PSMB7	NPM1	PSMB4	RANBP1	PSMB5	PSMB2	PSMB3	HMGA1	AP2A1	PSMB1	PSMF1	PSIP1	SHFM1	PSMB8	AP2A2	PSMB9	KPNA1	PSMC5	PSMC6	KPNB1	AP1G1	PSMC3	PACS1	PSMC4	AP2M1	AP1B1	PSMC1	AP1S2	PSMC2	AP1S1	AP1S3	HLA-A	B2M	AP1M2	CUL5	AP1M1	RAN	NUP107	NUP188	BANF1	ELMO1	AP2S1	NUP214	NUP210	CD4	NUP93	AP2B1	NUP205	POM121	AAAS	LCK	NUP160	NUP85	TPR	CD28	RBX1	NUP88	FYN	NUP155	BTRC	SKP1	NUP153	CD8B	
INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1%REACTOME DATABASE ID RELEASE 74%113501	Inhibition of replication initiation of damaged DNA by RB1 E2F1	POLA2	PPP2CA	PPP2CB	PPP2R1A	PPP2R3B	RB1	TFDP1	TFDP2	PRIM2	PPP2R1B	PRIM1	E2F1	POLA1	
DEFECTIVE MMADHC CAUSES METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE CBLD%REACTOME%R-HSA-3359473.1	Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD	MMACHC	MMADHC	
DISINHIBITION OF SNARE FORMATION%REACTOME%R-HSA-114516.4	Disinhibition of SNARE formation	PRKCG	PRKCB	PRKCA	STX4	STXBP3	
REPRESSION OF WNT TARGET GENES%REACTOME%R-HSA-4641265.3	Repression of WNT target genes	TLE1	CTBP2	AES	HDAC1	TLE3	LEF1	TCF7L2	CTBP1	TCF7	TLE4	TLE2	TCF7L1	
TYPE I HEMIDESMOSOME ASSEMBLY%REACTOME DATABASE ID RELEASE 74%446107	Type I hemidesmosome assembly	LAMB3	PLEC	ITGA6	DST	CD151	LAMA3	COL17A1	ITGB4	LAMC2	
DEFECTIVE GCK CAUSES MATURITY-ONSET DIABETES OF THE YOUNG 2 (MODY2)%REACTOME%R-HSA-5619073.2	Defective GCK causes maturity-onset diabetes of the young 2 (MODY2)	GCK	
EUKARYOTIC TRANSLATION INITIATION%REACTOME%R-HSA-72613.3	Eukaryotic Translation Initiation	UBA52	EIF2S2	EIF2S1	EIF2S3	RPS27A	RPL4	EIF4A2	EIF4A1	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	EIF1AX	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	EIF4EBP1	EIF2B5	RPL39L	EIF2B4	EIF2B3	RPL41	EIF2B2	RPL3L	RPS26	RPS25	RPS28	EIF5	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	EIF2B1	EIF5B	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	PABPC1	RPS27L	RPS15A	RPL14	RPS3	EIF4H	RPL13	RPL15	RPS2	RPL18	RPL17	EIF4E	EIF4B	RPL19	RPL35A	RPL23A	EIF3M	EIF3K	EIF3L	EIF3I	EIF4G1	EIF3J	EIF3G	EIF3H	EIF3E	RPL22L1	EIF3F	FAU	EIF3C	EIF3D	EIF3A	RPL26L1	EIF3B	
MRNA SPLICING%REACTOME%R-HSA-72172.3	mRNA Splicing	SKIV2L2	CPSF7	CPSF1	CPSF3	CSTF3	CSTF2	CPSF2	HNRNPU	CSTF2T	HNRNPR	WDR33	CCAR1	NUDT21	SNRPD2	FIP1L1	SNRPD1	CLP1	SNRPD3	PCF11	PAPOLA	SRRM2	AQR	CSTF1	SYMPK	CRNKL1	CD2BP2	SF1	DHX9	RNPC3	PCBP1	PCBP2	ZRSR2	PRPF38A	HNRNPL	HNRNPM	HNRNPK	HNRNPF	HNRNPD	HNRNPC	SUGP1	PRPF19	PQBP1	DHX15	DHX16	PRPF40A	GCFC2	HNRNPH1	HNRNPH2	SF3B4	SF3B5	SF3B2	SF3B3	SF3B6	SRRT	SRSF10	SF3B1	SF3A3	SF3A1	SF3A2	XAB2	PHF5A	HNRNPA2B1	PRPF31	PDCD7	CWC25	CWC27	EFTUD2	CWC22	SNRNP35	TXNL4A	SNRPN	ZCRB1	WBP11	PRPF4	PRPF6	HNRNPUL1	EIF4A3	PRPF3	POLR2A	CASC3	SNRPG	POLR2B	SNRNP27	POLR2C	MAGOH	PPIE	PPIH	NCBP1	POLR2D	SNRPE	NCBP2	SNRPF	POLR2E	SNRNP25	POLR2F	SNRPC	SNRNP200	POLR2G	SNRPA	POLR2H	CDC40	SNRPB	POLR2I	SRRM1	DDX5	POLR2J	PRPF8	ZMAT5	POLR2K	FUS	POLR2L	CWC15	CHERP	SRSF2	LSM8	SRSF3	ISY1	SRSF4	DDX46	SRSF5	DDX42	SRSF6	PPWD1	YBX1	SRSF7	USP39	ELAVL2	SLU7	SRSF9	PTBP1	SART1	RBM8A	SNRNP70	CTNNBL1	BCAS2	SRSF1	RBM5	U2AF1	RBM17	U2AF1L4	BUD31	TFIP11	PLRG1	U2AF2	DHX38	SYF2	SNRPA1	SRSF11	DNAJC8	UPF3B	RBM22	MAGOHB	PRCC	WBP4	RNPS1	DDX23	PUF60	TRA2B	SNRPB2	HNRNPA1	SMNDC1	HNRNPA0	PPIL1	HNRNPA3	GPKOW	CDC5L	U2SURP	SNRNP40	ELAVL1	SNRNP48	PPIL3	PPIL4	RBMX	PPIL6	LSM5	LSM4	LSM3	LSM2	GTF2F1	GTF2F2	LSM7	LSM6	CPSF4	HSPA8	SNW1	PABPN1	NHP2L1	
CA-DEPENDENT EVENTS%REACTOME%R-HSA-111996.1	Ca-dependent events	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	CAMK2G	CREB1	ADCY5	PLA2G4A	PRKCA	PRKCG	PDE1C	PDE1B	PDE1A	ADRBK1	CAMKK1	PRKCD	CAMKK2	PRKAR2B	PRKACG	PRKACB	KPNA2	NBEA	CAMK4	ADCY9	PRKAR1B	MAPK1	PRKAR1A	PRKX	CAMK2A	PRKAR2A	PRKACA	CAMK2B	ADCY4	CAMK2D	ADCY3	
RECRUITMENT AND ATM-MEDIATED PHOSPHORYLATION OF REPAIR AND SIGNALING PROTEINS AT DNA DOUBLE STRAND BREAKS%REACTOME%R-HSA-5693565.2	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	BABAM1	HERC2	UIMC1	WHSC1	CHEK2	BAZ1B	RNF168	RNF8	BRCC3	APBB1	TP53BP1	ABL1	KDM4B	UBA52	EYA1	H2AFX	EYA2	EYA3	EYA4	BAP1	HIST2H2BE	BRE	FAM175A	HIST4H4	SMARCA5	PIAS4	UBE2N	HIST1H2BN	UBB	HIST1H2BM	HIST1H2BO	HIST1H2BJ	UBC	HIST1H2BI	BRCA1	HIST1H2BL	MAPK8	NBN	RPS27A	HIST1H2BK	HIST2H4A	HIST2H4B	KDM4A	MRE11A	HIST3H3	RAD50	SUMO1	UBE2I	BARD1	HIST3H2BB	MDC1	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	ATM	HIST1H2BD	HIST1H2BC	UBE2V2	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	PPP5C	HIST1H4E	HIST1H4F	TP53	
ENTRY OF INFLUENZA VIRION INTO HOST CELL VIA ENDOCYTOSIS%REACTOME DATABASE ID RELEASE 74%168275	Entry of Influenza Virion into Host Cell via Endocytosis	CLTC	CLTA	
CASPASE-MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS%REACTOME DATABASE ID RELEASE 74%264870	Caspase-mediated cleavage of cytoskeletal proteins	PLEC	GSN	SPTAN1	VIM	CASP8	CASP3	CASP7	DBNL	CASP6	GAS2	ADD1	MAPT	
REGULATION OF GENE EXPRESSION IN BETA CELLS%REACTOME DATABASE ID RELEASE 74%210745	Regulation of gene expression in beta cells	SLC2A2	AKT1	NKX2-2	FOXO1	NEUROD1	RFX6	IAPP	INS	GCK	NKX6-1	PDX1	FOXA3	FOXA2	MAFA	HNF4G	HNF1A	PAX6	AKT2	AKT3	
EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS%REACTOME%R-HSA-168274.3	Export of Viral Ribonucleoproteins from Nucleus	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	XPO1	NUP205	NUP54	POM121	AAAS	NUP160	NUP85	TPR	NUP88	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	RAN	NUP107	NUP153	NUP188	
UPTAKE AND FUNCTION OF ANTHRAX TOXINS%REACTOME%R-HSA-5210891.2	Uptake and function of anthrax toxins	MAP2K4	PDCD6IP	MAP2K1	MAP2K2	FURIN	MAP2K7	
SIGNALING BY GPCR%REACTOME%R-HSA-372790.4	Signaling by GPCR	OR11A1	OR8A1	OR8I2	OR52N1	RRH	OR52N5	OR52N4	OR52N2	EDNRA	OR5D18	EDNRB	OR10W1	OR2A42	OR5D16	OR5D14	OR5D13	OR8H3	OR8H2	UTS2R	OR8H1	GPR37L1	OR52M1	UTS2B	OR10V1	ABCA4	OR4C12	OR6C6	OR4C11	OR6C4	OR6C3	OR4C16	CXCR4	OR8G5	OR6C2	OR4C15	OR5AK2	OR6C1	OR4C13	OR8G1	OR10T2	OR52L1	NLN	PPY	OR6B3	OR6B2	OR6B1	PDYN	NTSR1	APOA1	SLC24A1	CCR10	NTSR2	PIK3CG	OR2A25	NMB	VAV1	XCR1	PIK3R5	PDE2A	OR10S1	NMBR	OR52K2	OR52K1	NMS	NMU	PDE3A	OR2A12	OR6A2	OR2A14	OR2A1	OR4E2	CX3CL1	BRS3	CCKAR	FFAR3	OR4D9	FFAR2	OR5AP2	OR5B12	OR4D6	OR4D5	OR5B17	OR4D2	OR4D1	EDN1	EDN2	EDN3	OR10Z1	CCKBR	OR52R1	OR4C6	OR4C5	OR4A15	OR4C3	OR4A16	OR8K5	NPB	OR8K3	OR8K1	CXCR5	CXCR6	CXCR1	NPW	CXCR3	CXCR2	KISS1R	OR5AN1	OR4B1	OR4C46	OR6F1	OR8J3	OR8J1	OR10X1	F2RL1	OR4A5	CCL4L2	PMCH	NPY2R	OR6M1	OR2T12	OR2T10	OR2T11	OR5H15	OR5H14	PDE8B	PDE8A	GHSR	OR2D3	OR2D2	OR52E4	OR52E2	NPY1R	OR5AC2	APLNR	OR52E8	OR52E6	OR52E5	OR2C3	OR6K6	OR2C1	SUCNR1	OR6K3	OR6K2	OR52D1	NTS	OR2B6	OR4F6	OR2B3	OR4F5	OR2B2	OR10K2	OR4F4	OR4F3	OR10K1	OPN4	OPN3	OR6J1	OPN5	PYY	NMUR2	PRKCD	NMUR1	OR2A7	OR2A5	OR2A4	OR2A2	TAS2R7	GPSM1	CXCL6	GPSM2	TAS2R9	CXCL9	OR52J3	TAS2R8	MLNR	OR4M2	OR4M1	OR10R2	PSAP	CXCL3	OR6Q1	CXCL5	CCR5	OR8U1	BDKRB2	BDKRB1	TAS2R1	PPBP	TAS2R3	TAS2R5	GPSM3	TAS2R4	OR52I2	OR52I1	NPY5R	OR2H2	VAV3	OR2H1	OR4L1	VAV2	OR6P1	OR10Q1	CORT	BTK	RGS18	OR2G6	RGS17	OR52H1	RGS19	OR2G3	OR4K5	RGS14	NPY4R	OR2G2	RGS13	P2RY12	RGS16	OR4K2	OPRL1	OR4K1	OR10P1	OR2T34	OR8S1	OR2T35	OR2T33	PDE11A	RGS21	RGS20	S1PR3	S1PR2	RGS22	S1PR5	S1PR4	OR2T27	OR2F2	OR2F1	OR2T29	OR6N2	PRKACG	OR6N1	PRKACB	KISS1	PDE10A	RGS10	RGS12	PDE7B	ADCY9	PDE7A	PRKAR1B	SMO	PRKAR1A	PRKAR2A	PTCH1	GNAS	ADCY4	ADCY3	ADCY2	OXTR	ADCY1	AVPR1B	OXT	ADCY8	ADCY7	AVPR1A	ADCY6	ADCY5	HBEGF	FNTA	FNTB	PIK3R6	GABBR2	GABBR1	PPP1CA	RASGRF2	PDE3B	ARRB1	ARRB2	HEBP1	ANXA1	FPR1	FPR3	FPR2	PPP2R5D	CCL11	AKR1C3	CCL19	CCL22	CCL20	CAMK2B	CAMK2D	CAMK2G	CXCL10	CCL5	CCL4	CCL3	OPN1SW	OPN1MW	OPN1LW	RBP3	OPN1MW2	CCR1	DHRS3	RLBP1	CCR2	OPRD1	CCL3L1	CCL3L3	CXCL1	CXCL2	C3	GPR17	P2RY13	P2RY10	P2RY14	LPAR4	P2RY6	APP	P2RY4	LPAR6	P2RY2	ADORA3	P2RY1	ADORA1	PREX1	ARHGEF40	TIAM2	OBSCN	ARHGEF26	ABR	ECT2	ARHGEF33	ARHGEF35	ARHGEF37	ARHGEF39	RGS9	ARHGEF38	RGS6	RGS7	NET1	ARHGEF10L	AKAP13	MCF2L	ARHGEF10	PLEKHG2	ARHGEF15	MAPK7	PLEKHG5	ARHGEF17	ARHGEF16	ARHGEF19	SSTR3	MCHR1	ARHGEF18	SAA1	ARHGEF9	ARHGEF3	RGS11	ARHGEF4	ARHGEF1	ARHGEF2	ARHGEF5	ARHGEF6	FGD1	FGD2	GNA13	FGD3	FGD4	MCF2	GRP	FFAR4	FFAR1	SST	NPFFR2	NPFFR1	NPFF	QRFPR	HCRT	QRFP	HCRTR2	HCRTR1	GNA14	GNA15	GNA11	GNA12	GNAQ	F2RL2	F2RL3	ADORA2A	GNGT1	PPP3CA	PPP3CB	GNGT2	GNAT2	WNT5A	PLCB3	PLCB1	PLCB2	CAMK2A	ITPR1	ITPR2	ITPR3	GNG3	GNG10	PPP3R1	GNG2	WNT11	GNG5	GNG4	GNG7	GNG8	PDE6B	PDE6A	FZD3	FZD2	FZD5	PDE6G	FZD4	FZD6	GNG12	GNG11	GNG13	GNAO1	GNB2	GNB1	GNB4	GNB3	CDK5	GNB5	CDC42	ARHGEF11	ARHGEF12	ROCK1	ROCK2	RHOC	RHOA	RHOB	PLXNB1	PPP3CC	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	AGTR1	EGFR	NRAS	SOS1	HRAS	RXFP1	RXFP2	GPR176	GNAT3	C3AR1	PTGDR	LHB	CRHR2	MC2R	CGA	GPR15	MC1R	GPR27	APOA2	GPR25	GPR20	APOA4	MC4R	GPR39	NPY	FSHB	GPR32	GPBAR1	MC3R	FSHR	TACR1	NPSR1	PTGER4	GPR45	PTGER2	LPL	GNAI3	GNAI1	GNAI2	NPS	APOE	APOB	GPR150	LDLR	GPHA2	P2RY11	ADRBK2	GPIHBP1	MC5R	GPHB5	OPRM1	CYSLTR1	LHCGR	APOC3	GNAZ	APOC2	GPR83	GPR84	OPRK1	RLN2	RLN3	INSL3	TSHB	PTGIR	AVPR2	ADORA2B	TSHR	POMC	PPP2R1A	PRKACA	CLPS	PNLIP	LRP1	LRP2	PRKAR2B	CXCL8	CCL2	NMT1	NMT2	PLB1	C5AR2	C5AR1	C5	SRC	AVP	CREB1	PLA2G4A	MGLL	AWAT2	CAMKK1	CAMKK2	NBEA	CAMK4	SDC4	SDC3	GPC3	SDC1	GPC2	GPC5	GPC4	GPC6	PTGFR	TBXA2R	PTGDR2	GUCA1B	GUCA1A	PTGER1	GUCA1C	PTGER3	CNGA1	CAMKMT	RBP2	RGS9BP	SAG	PPEF1	GUCY2D	RETSAT	GUCY2F	LRP8	GRK1	APOM	GRK7	BCO2	BCO1	RCVRN	AKR1C1	AKR1C4	AKR1B10	LRP10	METAP1	LRP12	METAP2	AGT	GNAL	KPNA2	AHCYL1	PRKX	PPP2R1B	PRKCB	PRKCA	CD55	ITSN1	NGEF	PPP2CA	PPP2CB	MAPK1	AGRN	GLP1R	UCN	VIPR1	WNT2B	VIPR2	SCT	IHH	ADM	PTH1R	FZD10	ADGRE1	ADGRE2	CRHBP	SHH	CYSLTR2	ADGRE5	UCN3	UCN2	ADGRE3	GLP2R	WNT9B	PTH2R	WNT9A	WNT16	CXCL12	GIP	ADCYAP1	CRH	IAPP	CALCA	RAMP2	RHO	ADCYAP1R1	RAMP3	CALCRL	CALCB	DHH	GIPR	PTH	WNT8A	WNT8B	PTH2	CNGB1	PTHLH	CRHR1	OR2M7	GHRHR	OR2M5	WNT6	OR2M4	CALCR	OR2M3	WNT1	OR4K17	WNT2	OR2M2	WNT3	OR4Q3	WNT4	OR2L8	FZD1	OR2L5	WNT10B	OR2L3	WNT10A	OR4P4	WNT3A	OR2L2	FZD7	OR10AD1	WNT7B	OR6T1	PTCH2	OR4K15	FZD9	OR4K14	SCTR	OR4K13	FZD8	AGTR2	WNT7A	OR2K2	GCG	OR6S1	ADM2	NPBWR1	GHRH	NPBWR2	VIP	OR10D3	RAMP1	OR8B12	PRKCQ	OR14K1	OR4N5	OR2J3	RASGRP2	OR4N4	RASGRP1	OR2J2	OR2J1	OR4N2	OR10C1	GPR18	OR10J1	OR10J3	OR10J5	GPRC6A	OR6Y1	OR52B2	OR52B6	GPR37	SDC2	GPR35	GPR31	OR6X1	KALRN	OR52A1	OR52A5	OR10H1	OR10H3	OR10H2	OR10H5	OR10H4	OR4S2	OR4S1	PROKR1	PROKR2	OR10G2	OR14A16	OR10G4	GPR55	OR10G3	OR6V1	OR10G6	OR10G8	OR10G7	OR10G9	GPR68	GPR65	CXCL13	CXCL16	OR14C36	OR2T8	OR2T7	OR2T6	ARHGEF7	OR2T5	OR2T4	OR2T3	OR2T2	OR2T1	GPC1	OR4X2	OR4X1	OR9A4	OR51T1	OR9A2	UTS2	OR2S2	OR51S1	CXCL11	OR7E24	OR7A10	OR14J1	ECE1	OR2Y1	OR56B1	PRLHR	PDPK1	OR56B4	OR7A17	OR14I1	PIK3R3	OR10A7	PIK3R2	OR56A5	PIK3R1	OR7A5	PIK3CA	OR10A2	OR56A4	AKT2	OR10A4	AKT3	OR10A3	OR56A3	OR10A6	OR10A5	AKT1	OR56A1	CCL7	OR2W3	OR2W1	CCL1	OR12D3	OR12D2	APLN	OR51V1	OR2V2	OR2V1	OR7G2	OR7G1	OR9K2	TAS2R20	RGSL1	OR51L1	OXER1	OR5B3	OR5B2	TAS2R10	TAS2R13	TAS2R14	TAS2R16	TAS2R19	KEL	OR2AT4	OR5A2	PAK1	OR5A1	OR9I1	TAS2R40	TAS2R41	TAS2R42	TAS2R43	LPAR1	TAS2R46	LPAR2	LPAR3	OR51J1	PENK	OR7D4	OR7D2	TAS2R30	OR51I2	TAS2R31	TAS2R38	GNAT1	TAS2R39	PRKCG	OR51I1	PLCB4	LPAR5	PDE1C	GNRH2	PDE1B	OR4D11	PDE1A	GNRH1	ADRBK1	OR4D10	OR2Z1	OR9G4	OR7C2	OR7C1	OR9G1	TAS2R60	MLN	OR51Q1	GNRHR	TRIO	CCR9	CCR8	CCR7	CCR6	CCR4	CCR3	OXGR1	TAS2R50	OR5F1	GAL	OR3A3	OR14A2	OR3A2	OR3A1	PRLH	OR51M1	XK	OR5C1	OR7G3	OR1C1	OR5K4	OR5K3	SDR9C7	MYO7A	OR5K2	HSD17B6	OR51D1	RPE65	OR5K1	RBP4	RGS4	RGS5	TTR	RDH12	RGS2	RGS3	DHRS9	RDH11	RGS1	CCRL2	CYP4V2	RDH10	RGS8	HSD17B1	CASR	RBP1	OR1B1	NAPEPLD	OR5J2	RDH16	PCP2	PTAFR	OR1A2	RDH5	LRAT	OR1A1	OR51B2	STRA6	ARHGEF25	OR5I1	OR9Q2	OR9Q1	MCHR2	HCAR2	HCAR3	OR2AK2	HCAR1	GRK5	GRK6	OR51B6	OR51B5	TAC3	OR51B4	TAC1	OR5H6	OR5H2	OR5H1	OR2AJ1	OR51A4	OR51A2	OR51A7	RTP4	RTP5	RTP2	OR51H1	RTP3	RTP1	OR1G1	OR10AG1	GRM1	LTB4R	GRM3	GRM2	GRM5	GRM4	GRM7	GRM6	GPER1	GRM8	OR51G2	OR51G1	OR1F1	SSTR1	HSPG2	SSTR2	SSTR4	SSTR5	OR2AP1	OR2B11	OR51F2	DGKG	OR51F1	DGKE	OR5M9	DGKD	OR5M8	DAGLA	OR1E2	DGKB	OR1E1	DGKA	OR5M3	ABHD6	OR5M1	ABHD12	CNR2	PRKCH	CNR1	PRKCE	OR4F29	DGKZ	TAS1R2	DGKQ	TAS1R1	DAGLB	TAS1R3	DGKK	OR4F21	DGKI	OR51E1	DGKH	OR1D5	OR1D2	OR51E2	OR5L2	OR5L1	CCK	OR4F17	OR4F16	OR4F15	CHRM2	ACKR4	CHRM3	ACKR3	CHRM1	ACKR2	CHRM4	ACKR1	CHRM5	HTR2B	OR11H2	HTR2C	OR11H1	OR11H4	ADRA1D	RXFP4	ADRB1	HTR2A	OR1K1	GRPR	ADRB2	RXFP3	ADRA1B	HTR4	OR2AE1	OR11H6	ADRA1A	PROK2	HRH1	HTR6	PROK1	HTR7	CMKLR1	TRPC7	OR1J4	HRH3	OR11G2	HRH2	OR1J2	TRPC6	HRH4	OR1J1	DRD1	OR5R1	DRD2	TRPC3	TRHR	DRD3	MMP3	OR13J1	DRD4	OR1I1	DRD5	TAAR8	OR5M11	HTR1E	OR5M10	TAAR9	GALR3	HTR1F	GALR2	TAAR6	GALR1	HTR1D	OR5P3	HTR1A	OR5P2	HTR1B	GPR183	TAAR5	PNOC	TAAR2	OR11L1	GPR132	ADRA2C	HTR5A	OR5W2	TAAR1	GAST	TACR2	ADRA2A	TACR3	GPR143	SOS2	OR1N2	ADRB3	OR1N1	OR5V1	RGR	CCL13	OR1M1	OR2AG1	OR2AG2	CCL17	CCL16	CCL25	CCL21	OR1L8	OR1L6	OR1L4	GPR4	OR1L3	OR1L1	OR5T3	OR5T2	OR5T1	CCL28	CCL27	OR52W1	OR1S2	OR1S1	OR13D1	OR5AS1	MTNR1A	OR13C9	S1PR1	OR13C8	LTB4R2	MTNR1B	OR2L13	OR13C3	OR13C2	OR13C5	OR13C4	OR5AR1	KNG1	OR1Q1	TIAM1	PDE4B	OR4A47	PDE4A	OR5B21	PDE4D	REEP1	PDE4C	PPP1R1B	REEP5	REEP4	REEP3	REEP2	REEP6	OR13A1	OR13H1	TRH	OR8D4	OR8D2	F2R	OR8D1	INSL5	OR6C70	F2	OR6C76	OR6C75	OR6C74	OR13G1	XCL2	XCL1	CX3CR1	OR6C65	OR8B8	OR8B4	OR6C68	OR13F1	OR8B3	PF4	OR8B2	OR5AU1	
DEFECTIVE SERPING1 CAUSES HEREDITARY ANGIOEDEMA%REACTOME%R-HSA-9657689.1	Defective SERPING1 causes hereditary angioedema	KLKB1	SERPING1	F12	
ABACAVIR TRANSMEMBRANE TRANSPORT%REACTOME%R-HSA-2161517.2	Abacavir transmembrane transport	ABCG2	SLC22A2	SLC22A1	ABCB1	SLC22A3	
DAP12 INTERACTIONS%REACTOME DATABASE ID RELEASE 74%2172127	DAP12 interactions	KLRD1	TREM1	NRAS	PLCG1	SOS1	HRAS	PIK3R2	PIK3R1	TREM2	SYK	PIK3CA	TYROBP	LCK	GRAP2	LCP2	FYN	RAC1	B2M	PIK3CB	HLA-B	HLA-C	KIR3DS1	SIRPB1	PLCG2	KLRK1	HLA-E	CLEC5A	CD300LB	VAV3	SIGLEC15	SIGLEC14	VAV2	KLRC2	KIR2DS2	KIR2DS4	BTK	NCR2	CD300E	
PYRUVATE METABOLISM%REACTOME%R-HSA-70268.6	Pyruvate metabolism	RXRA	PDHA2	PDHA1	GLO1	LDHC	LDHB	LDHA	PDPR	MPC1	MPC2	PDK4	PDK3	PDK2	VDAC1	PDK1	PDP1	PDP2	LDHAL6A	LDHAL6B	PDHB	SLC16A1	PPARD	DLAT	BSG	GSTZ1	ME1	SLC16A8	SLC16A3	DLD	PDHX	
NEGATIVE REGULATION OF ACTIVITY OF TFAP2 (AP-2) FAMILY TRANSCRIPTION FACTORS%REACTOME DATABASE ID RELEASE 74%8866904	Negative regulation of activity of TFAP2 (AP-2) family transcription factors	TFAP2D	TFAP2E	SUMO1	UBE2I	KCTD1	KCTD15	TFAP2A	TFAP2B	WWOX	TFAP2C	
PENTOSE PHOSPHATE PATHWAY%REACTOME%R-HSA-71336.6	Pentose phosphate pathway	PRPS2	PRPS1	RPEL1	RPE	PGD	TALDO1	DERA	RPIA	TKT	SHPK	G6PD	PGLS	RBKS	PGM2	
SIGNALING BY RAS MUTANTS%REACTOME%R-HSA-6802949.2	Signaling by RAS mutants	MAPK3	RAF1	CSK	PHB	CAMK2G	SRC	RAP1B	RAP1A	MARK3	KRAS	YWHAB	NRAS	FN1	CNKSR2	HRAS	APBB1IP	CNKSR1	MAP3K11	ITGB3	ARRB1	ARAF	ARRB2	MAPK1	FGB	FGA	ITGA2B	VWF	CAMK2A	PEBP1	KSR1	FGG	TLN1	KSR2	IQGAP1	JAK2	BRAP	BRAF	MAP2K1	MAP2K2	CAMK2B	VCL	CAMK2D	
ACTIVATION OF RAS IN B CELLS%REACTOME DATABASE ID RELEASE 74%1169092	Activation of RAS in B cells	RASGRP1	NRAS	HRAS	RASGRP3	
AGGREPHAGY%REACTOME%R-HSA-9646399.3	Aggrephagy	RPS27A	DYNLL1	DYNC1LI1	PCNT	IFT88	DYNC1LI2	ARL13B	DYNLL2	DYNC1H1	HDAC6	CFTR	VCP	UBA52	HSF1	UBE2V1	DYNC1I2	HSP90AA1	CETN1	UBE2N	PARK7	UBB	DYNC1I1	PARK2	UBC	
DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS%REACTOME%R-HSA-5678895.2	Defective CFTR causes cystic fibrosis	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	CFTR	PSMD10	PSMB11	VCP	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	SEL1L	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	ERLIN1	PSMB3	UBC	PSMB1	ERLIN2	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	RNF185	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	DERL3	DERL1	DERL2	RNF5	ERLEC1	OS9	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA%REACTOME%R-HSA-139915.5	Activation of PUMA and translocation to mitochondria	TP53BP2	TFDP1	TFDP2	PPP1R13B	TP73	TP63	BBC3	E2F1	TP53	
APC C:CDC20 MEDIATED DEGRADATION OF CYCLIN B%REACTOME%R-HSA-174048.2	APC C:Cdc20 mediated degradation of Cyclin B	RPS27A	UBE2C	UBE2D1	CDC23	UBE2S	CDC26	CDC16	CDC27	ANAPC7	UBA52	UBE2E1	CDK1	ANAPC4	ANAPC5	CDC20	CCNB1	UBB	ANAPC1	ANAPC2	ANAPC15	ANAPC16	UBC	ANAPC10	ANAPC11	
SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27-HYDROXYCHOLESTEROL%REACTOME DATABASE ID RELEASE 74%193807	Synthesis of bile acids and bile salts via 27-hydroxycholesterol	RXRA	PTGIS	AKR1C1	CYP7B1	AKR1C4	CYP7A1	NCOA1	NCOA2	NR1H4	AKR1C3	CYP8B1	CYP27A1	HSD3B7	AKR1D1	AKR1C2	
DISEASES OF METABOLISM%REACTOME%R-HSA-5668914.3	Diseases of metabolism	B4GALT7	CHST3	CHSY1	SLC26A2	UBA52	GAA	ABCA3	UBB	GYG2	GYG1	UBC	CYP11A1	RPS27A	CYP7B1	MAOA	GYS1	B4GALT1	AGRN	DPM1	DPM2	DPM3	TALDO1	GALT	GALE	PGM1	GALK1	GCLC	GCLM	OPLAH	MTRR	CYP1B1	AHCY	TPMT	MTR	MAT1A	MGAT2	ST3GAL3	NOTCH1	MOGS	MAN1B1	ADAMTS2	GFPT1	ADAMTS3	SDC2	CHST6	ADAMTS14	LUM	DPAGT1	OGN	ALG8	OMD	ALG9	IDH1	PRELP	ALG6	KERA	FMOD	ALG14	ALG3	GNS	ALG13	ALG12	ALG1	MPDU1	RFT1	SLC35D1	NOTCH3	NOTCH4	GPC1	UGT1A4	PAH	SLC34A2	MPI	ALG2	MMAA	MUT	G6PC	ALG11	DHDDS	GNE	NOTCH2	NEU1	CTSA	NUS1	CYP26B1	SRD5A3	CYP26C1	PMM2	GYS2	DOLK	GLB1	MMAB	CYP17A1	GALNT12	MUCL1	MUC17	MUC5B	MUC3A	MUC5AC	MUC1	MUC7	MUC12	IDUA	HEXB	MUC13	NCAN	MUC15	HEXA	MUC20	BGN	MUC4	ACY1	MUC21	VCAN	HYAL1	MUC6	IDS	SDC4	CSPG5	CSPG4	B3GAT3	SDC3	ARSB	GPC3	RPIA	SDC1	GPC2	GPC5	GPC4	GPC6	ALDOB	CSF2RB	CSF2RA	TBXAS1	BTD	PPP1R3C	NHLRC1	HLCS	GALNT3	TCN2	CD320	SFTA3	GBE1	SFTPB	SFTPC	SFTPD	EPM2A	ACACA	G6PC3	HGSNAT	GIF	DCXR	PCCA	PCCB	SFTPA2	GALNS	PC	MCCC2	CYP4F22	SFTPA1	SEMA5A	MCCC1	FDX1	FDXR	FDX1L	HSPG2	BCAN	GSS	ADAMTS16	ADAMTS18	ADAMTS4	ADAMTS5	ADAMTS1	CYP2U1	CYP27A1	ABCD4	ADAMTS8	CYP19A1	ADAMTS9	CYP27B1	MC2R	CUBN	CYP11B2	CYP11B1	AMN	CYP2R1	CYP21A2	DCN	FMO3	GGT1	LMBRD1	KHK	POMT2	SPON2	THBS1	SEMA5B	MMACHC	SPON1	MMADHC	THSD7B	POMT1	LFNG	ADAMTSL1	C1GALT1C1	DAG1	ADAMTSL4	ADAMTSL3	ADAMTSL2	THSD7A	ADAMTS6	ADAMTS7	SBSPON	POMGNT1	ADAMTS20	B3GLCT	THBS2	CFP	ADAMTS12	THSD1	ADAMTS10	NAGLU	POMC	THSD4	ADAMTS15	ADAMTS13	ADAMTS19	LARGE	ADAMTS17	C1GALT1	B4GAT1	CYP24A1	CHST14	B3GALT6	EXT1	EXT2	SI	PAPSS2	SGSH	LCT	GUSB	UGT1A1	
NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS%REACTOME DATABASE ID RELEASE 74%9013700	NOTCH4 Activation and Transmission of Signal to the Nucleus	NOTCH4	PSEN2	ADAM10	NCSTN	DLL4	APH1A	APH1B	YWHAZ	PSENEN	PSEN1	JAG1	
METABOLISM OF VITAMINS AND COFACTORS%REACTOME DATABASE ID RELEASE 74%196854	Metabolism of vitamins and cofactors	SLC5A8	MMAB	LRP1	LRP2	SHMT1	ABCC1	SDC4	APOA1	SDC3	GPC3	SDC1	GPC2	GPC5	GPC4	GPC6	RBP4	TTR	RDH11	RBP1	AGRN	RBP2	PTGS2	LRAT	RETSAT	LRP8	APOM	BCO2	BCO1	AKR1C1	AKR1C4	AKR1B10	LRP10	LRP12	BTD	HLCS	TCN2	CD320	PRSS1	SLC23A2	CYB5A	CYB5R3	GSTO2	SLC23A1	ACACA	GIF	PTGIS	PCCA	PCCB	PC	MCCC2	CTRB2	MCCC1	CTRB1	BST1	HSPG2	VNN1	VNN2	AKR1C3	CYP8B1	FOLR2	MTRR	NNMT	TTPA	GSTO1	MTR	ABCD4	SDC2	SLC2A1	CUBN	AMN	APOA2	APOA4	IDH1	PANK4	VKORC1L1	ALDH1L1	PANK2	PLB1	PANK3	LPL	PANK1	NADSYN1	ALDH1L2	FLAD1	ENPP2	ENPP1	APOE	NT5E	ENPP3	APOB	PRSS3	LDLR	MTHFD1	PDZD11	GPC1	MTHFD2	GPIHBP1	SLC2A3	MTHFD2L	UBIAD1	SHMT2	ACACB	LMBRD1	PPCS	PNPO	APOC3	SLC19A3	NADK	SLC5A6	SLC19A1	MMACHC	MMADHC	SLC19A2	APOC2	SLC52A2	SLC52A3	SLC52A1	MTHFR	MTHFS	COQ9	PARP16	COQ7	PARP14	COQ6	COQ5	PARP10	DHFR	PARP6	COQ3	PARP4	TCN1	PARP9	MMAA	FASN	MUT	PARP8	NOS3	CTRC	MOCS2	COQ2	MOCS3	QPRT	GPHN	AKT1	PPCDC	THTPA	NADK2	SPR	PRKG2	CARKD	DHFRL1	RNLS	APOA1BP	NMRK2	SLC22A13	RFK	SLC46A1	NAPRT	NMRK1	NAMPT	ACP5	NUDT12	AOX1	CD38	VKORC1	COASY	GCHFR	SLC25A16	SLC25A19	PDXK	PTS	HSP90AA1	MTHFD1L	PDSS2	PDSS1	AASDHPPT	CLPS	GCH1	TPK1	MOCOS	NMNAT3	PNLIP	NMNAT2	NMNAT1	SLC25A32	
IKK COMPLEX RECRUITMENT MEDIATED BY RIP1%REACTOME%R-HSA-937041.1	IKK complex recruitment mediated by RIP1	RIPK3	LY96	RPS27A	UBE2D2	TICAM1	UBE2D1	RIPK1	CD14	TRAF6	TLR4	UBA52	UBE2V1	IKBKB	BIRC2	BIRC3	UBE2N	UBB	UBE2D3	UBC	IKBKG	TICAM2	CHUK	
TRIGLYCERIDE CATABOLISM%REACTOME%R-HSA-163560.3	Triglyceride catabolism	FABP4	PLIN1	PPP1CB	CAV1	FABP9	ABHD5	FABP12	PRKACA	LIPE	GPD2	MGLL	FABP2	FABP3	FABP5	FABP6	PLIN3	PPP1CC	PNPLA4	PNPLA5	PPP1CA	FABP7	FABP1	PRKACG	PRKACB	
CROSS-PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS (PHAGOSOMES)%REACTOME%R-HSA-1236973.1	Cross-presentation of particulate exogenous antigens (phagosomes)	ITGB5	NCF1	NCF2	NCF4	CYBA	ITGAV	CD36	CYBB	
SIGNALING BY NUCLEAR RECEPTORS%REACTOME%R-HSA-9006931.5	Signaling by Nuclear Receptors	HIST2H2AC	FOS	ABCG8	H2AFJ	FOSB	ABCG5	ABCG1	H2AFZ	H2AFX	H2AFV	FABP5	HIST2H2BE	FABP6	HIST4H4	SPHK1	NRIP1	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	TBL1X	HIST1H2BK	HIST2H4A	PPARD	ZDHHC7	HIST2H4B	CRABP2	DLAT	KDM3A	MAPK1	GREB1	KDM1B	NR5A2	KDM4A	TFF1	ARL4C	KANK1	EEPD1	ZDHHC21	ZNF217	EBAG9	FOXA1	PPID	CAV2	CHD1	CXXC5	USF2	USF1	SCD	STRN	CITED1	PDHA2	TBL1XR1	PDHA1	YY1	POLR2A	POLR2B	POLR2C	POLR2D	PDHB	POLR2E	POLR2F	POLR2G	CXCL12	POLR2H	POLR2I	POLR2J	HSP90AB1	POLR2K	POLR2L	GTF2A1	GTF2A2	AXIN1	SP1	KDM4B	XPO1	PCK1	NCOA1	NCOA2	ESR1	NCOA3	APOD	FKBP4	RXRA	SRC	RXRB	PTGES3	PDPK1	S1PR3	RXRG	PIK3R3	PIK3R2	PIK3R1	PIK3CA	NOS3	AKT2	GPS2	AKT3	GNGT1	AKT1	GNGT2	CAV1	CCND1	EREG	BTC	TGFA	GNG3	GNG10	SMC3	KDM1A	ADH1C	GNG2	ADH1A	CRABP1	GNG5	UGT1A3	MYB	DHRS4	GNG4	CREBBP	ALDH1A3	GNG7	PTK2	CYP26A1	EP300	GNG8	ADH4	PPP5C	SDR16C5	CYP26B1	CYP26C1	RAD21	ALDH1A2	ALDH1A1	RDH14	RDH13	AREG	STAG1	ALDH8A1	STAG2	CREB1	GATA3	GNG12	GNG11	TLE3	GNG13	TNRC6C	MOV10	AGO3	AGO4	GNB2	SMC1A	AGO1	GNB1	AGO2	GNB4	GNB3	GNB5	TNRC6A	PDK4	TNRC6B	PDK3	PDK2	CCNT1	PDK1	CARM1	HBEGF	MYC	SRF	EPGN	FOXO3	UHMK1	GPAM	CDK9	MED1	DLD	HDAC1	DHRS9	RDH11	RDH10	RDH16	RDH5	RARG	PGR	FKBP5	NCOR2	NCOR1	CPT1A	RARA	RARB	PLIN1	BCL2	DDX5	AKR1C3	MAPK3	CDKN1B	CBFB	PRKCZ	CPT1B	PRMT1	EGF	EGFR	NRAS	HRAS	GNAT3	DHRS3	KPNA2	POU2F1	CTSD	TBP	GTF2F1	GTF2F2	MMP7	MMP2	MMP3	MYLIP	MMP9	ANGPTL3	CETP	KCTD6	HIST1H2AE	HIST1H2AD	HDAC3	HIST3H2BB	GNAI3	HIST1H2AC	GNAI1	HIST1H2AB	GNAI2	ESR2	APOE	HIST1H2AJ	ABCA1	NR1H2	APOC4	HIST2H3A	HIST1H2BF	NR1H3	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST2H3D	APOC2	HIST1H2BB	HIST2H3C	APOC1	HIST1H2BA	IGF1R	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	ATF2	FASN	ELK1	HIST1H3A	RUNX1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	JUN	KAT2B	H3F3A	H2BFS	HSP90AA1	JUND	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	PDHX	HIST2H2AA3	HIST2H2AA4	
IMMUNE SYSTEM%REACTOME%R-HSA-168256.7	Immune System	IFIH1	RNF135	MAVS	SIKE1	VCP	FCGR3B	PLAUR	TRAT1	PIK3AP1	APEH	RNF41	CXCR1	CXCR2	POLR2E	POLR2F	POLR2H	POLR2K	POLR2L	BST1	VNN1	YWHAB	LAMP2	PRKCD	YWHAZ	MAPKAPK2	STXBP2	A1BG	PSAP	CYFIP2	HSPA8	TNFSF13	NCKAP1	MAPK14	CYFIP1	WIPF1	MAPK11	ARPC1B	WIPF2	EIF4G1	PPBP	ARPC1A	WIPF3	BRK1	WASL	ACTB	ACTG1	NCK1	ACTR3	VAV3	ACTR2	SERPINA3	ORM1	VAV2	MYH2	ELMO1	BTK	ELMO2	WAS	NCKIPSD	ORM2	NCKAP1L	WASF1	WASF2	WASF3	MYO10	QSOX1	MYO5A	ARPC4	AHSG	MYO9B	ARPC5	BAIAP2	MYO1C	CD63	ABI2	ARPC2	ARPC3	ABI1	PRKACG	PRKACB	RBX1	KIF3A	KIR3DS1	SIRPB1	KLRK1	CLEC5A	CD300LB	SIGLEC15	SIGLEC14	KLRC2	KIR2DS2	KIR2DS4	NCR2	CD300E	KLRD1	ITCH	SLC2A5	DERA	GPI	IL1RL1	IL33	HK3	PARK2	PGAM1	ALDOC	ALDOA	PFKL	XDH	HGSNAT	GALNS	CDKN1A	PRSS3	ATF1	APP	ATF2	TCN1	UBE2D3	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	S100A1	CD180	CNPY3	VRK3	SIGIRR	MAPKAPK3	S100A9	S100A8	AGER	HSP90B1	SOCS1	IRAK1	S100A12	MAP2K7	MAP2K6	KIF5B	JUN	KIF5A	LY86	PDXK	NFKB2	MYD88	LGMN	ITGAM	KIFAP3	HPSE	ITGB2	HMGB1	EEA1	NKIRAS1	NKIRAS2	LBP	CD36	IKBKE	GUSB	DUSP3	RIPK3	RIPK2	DYNC1LI1	IRAK3	IRAK4	DYNC1LI2	FOS	TIRAP	DNM1	DNM2	TLR1	KIF20A	DNM3	TRAF3	IRF7	PELI1	TLR8	TLR7	COPB1	TLR10	FABP5	BPI	TLR6	KLC1	TLR5	BIRC2	KLC4	TLR3	KLC3	TLR2	CTLA4	KLC2	BIRC3	KIF3B	RACGAP1	UNC93B1	PELI3	PELI2	NOD1	NOD2	KIF3C	RAB6A	TANK	MAPK9	MAPK8	SURF4	MAPK7	MAP3K1	IGF2R	S100B	MAPK10	KIF18A	TNIP2	SAA1	PTPN4	KIF4B	KIF4A	ARF1	KIF11	IQGAP2	KIF15	CAPZB	TNFRSF6B	TNFSF11	TNFRSF8	TNFRSF4	EDAR	SNAP29	TNFRSF11B	TNFRSF11A	TNFRSF17	TNFSF18	TNFSF14	TNFSF15	KIF23	TNFSF12	KIF22	TNFRSF9	TNFSF4	UBA3	DYNLL2	CD27	RORC	TNFSF9	RORA	TNFSF8	EDA	TNFRSF13B	TNFRSF13C	EDA2R	TNFSF13B	EDARADD	KIF2A	TNFRSF12A	TNFRSF1B	LTA	TNFRSF25	KIF2C	LTB	KIF2B	CD70	CD40LG	SEC22B	LTBR	PAFAH1B2	VAMP3	DCTN6	DCTN5	DCTN1	DCTN4	PGM1	DYNC1I1	CENPE	CAPZA3	KIF26A	CAPZA1	CAPZA2	RAB18	FBXO32	ACTR10	CUL7	RAB9B	ITGAL	TRIM63	TNFRSF18	SEC31A	SIRPA	LGALS3	CXADR	MIF	CD99	SELL	TREM1	OLR1	AMICA1	FCER1G	CEACAM3	CD58	CD74	PPP3CA	PPP3CB	PRKG2	CAT	CAMK2A	RETN	ITPR1	ITPR2	NEU1	ITPR3	JUNB	PPP3R1	RNF111	CTSA	GLB1	NFATC1	AAMP	FOXO1	CTNNB1	AMPD3	APRT	PNP	HEXB	FOXO3	ARSB	WWP1	PTGS2	ROCK1	PPIA	NFATC3	NFATC2	LIMK1	RHOA	ERBB2	MYH9	CSF1R	CYB5R3	BCL2	LRRFIP1	STAT1	STAT3	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	CR1	SLC27A2	SHC1	EGF	GAB1	CBL	EGFR	NRAS	PLCG1	SOS1	HRAS	VEGFA	TWIST1	LIFR	KCTD6	SLC2A3	OPRM1	EGR1	KCNAB2	RALA	EIF4A2	EIF4A1	UBE2L3	PGLYRP4	PGLYRP3	PGLYRP2	GMFG	PGLYRP1	MCEMP1	NLRX1	UBE2V2	RNF216	RNF217	PRKDC	ATG5	FUCA2	TREML1	TREML4	UBE2J2	TREML2	DZIP3	RNF220	SIGLEC9	HCST	UBE2B	KIR3DL1	KIR3DL2	UBE2A	SIGLEC1	SIGLEC8	YPEL5	SIGLEC7	SIGLEC6	SIGLEC5	FBXO27	LTN1	FBXO21	FBXO22	TOM1	FBXW8	BTN1A1	FBXO17	FBXO15	FBXO10	FBXO11	ACLY	ARL8A	REG3A	REG3G	FBXO44	FBXO41	FBXO40	TKFC	FBXO30	FBXO31	OSBPL1A	NIT2	TRIM71	LEAP2	TRIM69	UNKL	PIANP	GSTO1	RNASET2	TMBIM1	ACPP	TRIM56	TRIM50	CANT1	MGRN1	RCHY1	ZNRF1	ZNRF2	RPLP0	RILP	TRIM41	TSPAN14	TRIM39	TRIM36	TRIM37	TRIM32	HERC4	HERC3	HERC1	FBXO7	HERC6	FBXO9	C6orf120	FBXO2	SLPI	CRISPLD2	CD226	TRIM11	C16orf62	TMEM63A	SYNGR1	EIF4E	NBEAL2	FBXL8	CD207	FBXL4	CD200	FBXL7	SH3RF1	ACTR1B	FCER1A	RAP2C	RNF144B	RAP2B	GAN	C1orf35	GCA	KLHL2	CD3E	KLHL3	CD3D	KLHL9	ICOSLG	KLHL5	HLA-DPA1	SEMG1	PDCD1LG2	OTUD5	HLA-DQB2	UBE3C	HLA-DQB1	CD274	UBE3D	UBE3A	BTLA	TNFRSF14	UBE3B	SRP14	HLA-DQA2	UBE2Z	HLA-DQA1	PLAU	TRAV19	HLA-DRB5	ENPP4	HLA-DRB4	FBXW12	UBE4A	CD4	IRS1	SRC	UBA6	HLA-DPB1	UBA5	HLA-DRA	HLA-DRB3	DAPP1	HLA-DRB1	ADGRG3	UBE2F	UBE2H	CRTAM	GGH	UBE2W	UBE2U	UBE2O	UBA1	UBE2K	SMAD3	MS4A3	TGFB1	TNFAIP6	UFL1	NCF1	TAPBP	NCF2	CHI3L1	NCF4	MS4A2	LPO	ASB13	MPO	RAC2	ASB14	RNF6	NOS1	ASB11	NOS2	RNF7	NOS3	ASB12	SLC11A1	RNF4	CYBB	ASB17	ASB18	ASB15	ASB16	ASB10	PTX3	GLA	CDA	FRMPD3	SEC61G	CLEC10A	ARMC8	ATG12	SEC61B	HECW2	ANAPC13	PLAC8	MEX3C	RAB7A	GNLY	PLEKHO2	GRN	TMEM179B	RAB3D	NPEPPS	RAB44	LAMP1	KCMF1	ILF2	RAB37	UBR4	EP300	UBR2	UBR1	CD300LD	CD300LF	CD300LG	UBOX5	MIB2	TPP2	FCAR	KBTBD13	FCER2	PKM	CREB1	FGL2	NLRC5	FBXL22	FBXL20	HECTD1	HECTD2	HECTD3	RAB24	FBXL19	FBXL18	VAPA	FBXL15	FBXL16	FBXL13	FBXL14	CPPED1	FBXL12	CALML5	CBLB	CD79B	CD79A	VAT1	SH2D1A	SH2D1B	RAET1E	DET1	MUCL1	MUC17	GPR75-ASB3	STIM1	MUC5B	CSTB	MUC3A	EPPIN-WFDC6	MUC5AC	P2RX1	CST3	ORAI2	LAIR2	MUC1	ORAI1	LAIR1	MUC7	MUC12	SVIP	MUC13	KBTBD6	MUC15	QPCT	MUC20	KBTBD8	SIPA1	MUC4	MUC21	COTL1	LMO7	MUC6	NLRP1	LONRF1	DBNL	BLMH	CASP4	DCD	AIM2	DEFB4A	DEFB4B	GSN	THOP1	LTF	CLEC12A	VIM	TMEM30A	RNASE6	RNASE3	SCAMP1	RNASE2	FLG2	PADI2	HACE1	AZU1	LYZ	HRNR	PIGR	LRSAM1	TMC6	LRRC41	SERPINB10	SERPINB12	HLA-DMA	HLA-DMB	RNASE8	RNASE7	SPSB2	SPSB1	LRG1	SPSB4	UBE2D4	DEFB1	STK10	HLA-DOA	HLA-DOB	LAG3	AREL1	UBE2E3	UBE2E2	OLFM4	S100A7	DEFA6	DEFA4	EIF4A3	ZBTB16	DEFA5	DEFA3	DEFA1	PTPRB	FAM47E-STBD1	LRMP	ZNF645	CECR1	TIFA	ERAP2	ERAP1	FCGR2B	LRR1	GLIPR1	CCNF	KEAP1	BPIFA1	BPIFA2	DHX58	ALPK1	DEFB103A	DEFB103B	CD1D	CD1C	CD1B	CD1A	UBE2J1	ART1	COMMD9	DHX36	SLAMF7	SLAMF6	PAG1	ALOX15	DEFB104B	DEFB104A	PRG2	STAT6	PILRB	PILRA	PRG3	BPIFB2	BPIFB1	BPIFB4	BPIFB6	CYSTM1	CD22	DEFB105A	DEFB105B	CTSO	ARIH2	CTSH	CTSF	CTSE	CD33	CD53	DEFB106B	COMMD3	DEFB106A	NCR1	NCR3	DEFB129	DEFB128	DEFB127	DEFB126	DEFB125	DEFB124	KPNA7	DEFB123	KPNA4	DEFB107A	KPNA5	DEFB121	KPNA2	DEFB107B	KPNA3	PGRMC1	KPNA1	CREG1	MICA	MICB	KPNB1	NPDC1	DEFB136	EIF2AK2	HUWE1	DEFB135	ISG15	CALR	DEFB134	UBE2G1	DEFB133	CLTC	UBE2G2	CLTA	DEFB108B	DNAJC3	DEFB132	CANX	DEFB131	CD68	OSTF1	EPPIN	CD96	CD93	ATAD3B	KLHL41	OSCAR	KLHL42	DOK3	CD8A	KLHL11	KIR2DL1	KLHL13	KIR2DL2	KIR2DL3	KIR2DL4	KLHL25	KLHL21	SPTAN1	KLHL22	KLHL20	TARM1	DDX3X	SPTB	SEC61A2	SPTBN4	SEC61A1	SPTBN5	UBE2Q1	UBE2Q2	SPTA1	DYNLT1	CD59	PJA2	CD55	PJA1	SPTBN1	UBE2R2	SPTBN2	MVP	VPRBP	DEFA1B	CHGA	PDAP1	ASB8	ASB9	LNX1	ASB6	ASB7	S100P	ASB4	ASB5	ASB2	ASB1	ABCA13	RNF115	RNF114	WSB1	NHLRC3	UNC13D	RNF123	RNF126	RNF125	CRACR2A	PRDX4	PPAPDC1A	PPAPDC1B	S100A11	GSDMD	PA2G4	MRC2	TRIM9	TRIM4	MRC1	SERPINB3	SERPINB1	NFAM1	SERPINB6	CD200R1	ASAH1	RNF138	METTL7A	AGA	RNF130	CARD9	ERP44	RLIM	GHDC	RNF19B	EPX	RNF19A	ATP8A1	DEFB119	DEFB118	MTAP	DEFB116	DEFB115	UBE2D1	TAP2	CDC23	DEFB114	CDC26	TAP1	CDC27	DEFB113	DEFB112	SKP2	ANAPC7	DEFB110	ATP11B	UBE2E1	TRAIP	ATP11A	CLEC4A	CLEC4C	CLEC4D	JUP	CLEC4E	CLEC4G	BRI3	ANAPC4	BTBD1	CLEC7A	NANOG	ANAPC5	BTN2A2	CD160	ANAPC1	BTN2A1	GLMN	ANAPC2	BTBD6	CLEC6A	RNF182	ANAPC10	TRPM2	NF2	ANAPC11	RNF14	PTPN22	S100A7A	GM2A	FZR1	DTX3L	TRAF7	ITLN1	RBBP6	RNF25	UBE2C	CLEC2B	MNDA	UBE2S	FOLR3	CDC16	CLEC2D	PTPRN2	ATP8B4	SIGLEC12	STK11IP	SIGLEC11	SIGLEC10	UBAC1	FAF2	MANBA	BTN3A1	BTN3A3	BTN3A2	DNASE1L1	MT2A	LILRA6	LILRA1	LILRA2	LILRA3	LILRA4	LILRA5	NCR3LG1	LILRB1	LILRB2	LILRB3	LILRB4	LILRB5	TRIP12	CD300A	ATP7A	KCTD7	KLRF1	CD300C	KLRB1	ANO6	DPP7	KLRC1	RAP1GAP2	PKP1	BTNL9	BTNL8	DNAJC13	BTNL2	DSC1	MAN2B1	ULBP1	ULBP3	CRISP3	HTN1	HTN3	RAP1GAP	HEBP2	CKAP4	MOSPD2	KLRG1	CMTM6	STOM	PTPRC	HSP90AB1	ITGAV	DSP	DSG1	DIAPH1	HERC2	UBE2D2	IGKV2-28	IGKV1-12	IGKV3D-20	CDC34	IGKV2D-28	TRAF6	IGKV4-1	IGHE	PRKCQ	UBE2V1	IGKV2D-30	RASGRP2	RASGRP1	RASGRP4	IGKV3-11	LYN	IGKV5-2	UBE2N	TAB3	STX1A	XRCC6	TAB2	XRCC5	TAB1	TREX1	NLRC3	DDX41	IFI16	MB21D1	AP1G1	AP1B1	AP1S2	AP1S1	AP1S3	SMARCA4	HLA-A	B2M	AP1M2	AP1M1	CAP1	ENAH	TICAM2	LY96	TRAF2	FASLG	TICAM1	CASP8	RIPK1	CD14	FADD	TLR4	ITGB1	IL6R	CEACAM1	SH3GL2	CEACAM6	FN1	CEACAM8	TYROBP	DLG1	DLG3	DLG4	NAPRT	MSN	CREBBP	ICAM2	ICAM3	RELB	PAK1	RPS6KA5	CD209	PAK3	RAF1	PAK2	NME2	TCEB2	MAPK13	TCEB1	RAG2	RAG1	TSLP	IL7	BRWD1	CRLF2	MYC	DHX9	PCBP2	HNRNPF	CAB39	HNRNPA2B1	FKBP1A	PPIE	ARSA	LAMTOR2	LAMTOR1	LAMTOR3	FYB	ZAP70	CSF3R	LAT	TNF	CD101	CFL1	SNRPA1	CUL2	PI3	CRCP	AIP	TREM2	INPP5D	POU2F1	POLR3GL	POLR3A	POLR3B	TRPC1	POLR3C	POLR3D	POLR3E	POLR1C	POLR3F	POLR3G	POLR3H	POLR3K	AOC1	EVL	SOS2	CEBPD	NFASC	IL21	IL21R	PITPNA	STAT4	SOX2	KRT1	PROS1	F13A1	PRCP	CD177	FGB	FGA	VWF	PPL	FGG	F2	VASP	SIAH2	SIAH1	SERPING1	PRTN3	SH3KBP1	PYGB	AGL	GAA	PYGL	SLC15A4	PGM2	MME	ATP6AP2	GYG1	ANPEP	STAT5A	STAT5B	PIK3CD	IRS2	ALAD	PIK3CB	VAV1	CRKL	RAPGEF1	PLCG2	JAK2	SDCBP	TALDO1	GSTA2	BLK	PANX1	PVR	CCR5	CUL5	GNS	PVRL2	CHRNB4	ARAF	WDR83	SYNGAP1	GOLGA7	ACTN2	PAQR3	FLT3LG	FRS2	FRS3	EREG	BTC	TLN1	PIK3R4	PDGFB	TGFA	IQGAP1	RCE1	RALGDS	BRAP	ICMT	BRAF	GRIN2B	PTK2	GRIN2D	PPP5C	ARTN	DSN1	RGL3	RGL1	RGL2	ITGB5	RET	AREG	ICAM4	PEA15	NEFL	ICAM5	JAK3	JAK1	ICAM1	DUSP4	DUSP5	ITGAX	LYPLA1	DUSP2	DUSP1	ITGB7	GFRA1	GAB2	DUSP8	GFRA3	BIRC5	IL17RD	DUSP9	GFRA2	CD47	DUSP6	VTN	DUSP7	GFRA4	CNKSR2	VCAM1	APBB1IP	HCK	CNKSR1	MRAS	PTPN12	LRRC7	KIT	TLR9	RAPGEF2	HBEGF	SHOC2	DAB2IP	RANBP9	USP17L2	GRIN1	EPGN	ZDHHC9	KBTBD7	KLB	CSF2	ITGA2B	PEBP1	MGST1	IL5RA	FGF1	FGF2	FGF3	FGF4	PPP1CC	FGF6	FGF7	FNTA	APAF1	FGF9	FNTB	NRTN	PDGFRB	PDGFRA	MAP2K1	CASP9	MAP2K2	HGF	VCL	SHC2	SHC3	CUL3	ARL2	CSF2RB	RASAL1	PHB	RASAL2	RASAL3	CSF2RA	RASGRP3	RAP1B	RAP1A	FGF20	MARK3	FGF23	NEDD4L	FGF22	PSPN	IL2	SMURF2	FGF16	SMURF1	IL3	IL5	DLG2	GDNF	PTPRA	STUB1	FGF19	FGF18	UBE2M	NF1	FGFR4	MAP3K11	BCL2L1	FGF10	FLT3	ITGB3	RASGRF2	PML	PDE3B	RASGRF1	ARRB1	ARRB2	DUSP16	SPRED3	SPRED2	SPRED1	CNTFR	CNTF	ANXA1	DUSP10	RASGEF1A	IL20RA	FPR1	PPP2R5E	IL20RB	FPR2	IL22RA2	KSR1	IL31RA	PPP2R5B	PPP2R5A	IL22RA1	PPP2R5D	HAVCR2	NRG1	SERPINB2	PPP2R5C	ANXA2	ZEB1	PTGES2	KSR2	NRG2	CCL11	RASA3	CTF1	STX3	NRG3	RASA4	CCL19	IL12RB1	NRG4	IL12RB2	RASA1	CCL22	IL3RA	RASA2	CCL20	IL10RB	PIK3C3	IL10RA	MET	CLCF1	CAMK2B	CRLF1	CAMK2D	CSF3	ABHD17C	IL2RG	CSF1	PIM1	PDE6D	IL13RA2	CSK	IL13RA1	NCAM1	TXLNA	CAMK2G	ANGPT1	FSCN1	IL6ST	PTPN11	BOLA2B	MAPK12	HNRNPDL	ABHD17B	ABHD17A	NDN	IL2RA	MCL1	IL2RB	SOCS5	KRAS	CXCL10	LCP1	TEK	PTPRZ1	PTPN7	CCL5	PTPN3	CCL4	CCL3	PDCD4	IL23R	IL27RA	IL12B	IL12A	LGALS9	IL15RA	IL23A	BOLA2	EBI3	CCR1	LIF	IFNLR1	GRB2	MLEC	IL22	IL20	IL25	PDIA3	IL26	IL24	IL27	CCR2	IL11	EEF1A1	IL15	IL19	IL16	EEF2	IL17RE	OSMR	IL17RC	IL17RB	IL17RA	OPRD1	IL32	IL31	IL34	OSM	BATF	IL17F	IL17C	IL17A	INPPL1	IL4R	IL11RA	CCL3L1	CCL3L3	CNN2	IL9	CXCL1	CXCL2	CA1	BLNK	IL9R	FCN1	IFNL2	CFD	IFNL1	PTK2B	CRP	C1QB	IFNL3	COLEC11	C1QA	FCN2	COLEC10	FCN3	C1S	C1R	C4B_2	C2	C3	C4B	IGHG4	C4A	IGHG1	IGHG2	MBL2	GZMM	MASP1	CFB	C1QC	CFP	RBCK1	SQSTM1	LAT2	FBXO4	FBXO6	FBXW4	FBXW5	CYLD	FBXW10	TNFAIP3	FBXW7	FBXW9	FBXW2	CASP10	CASP2	CCT2	TNFRSF1A	FBXL3	TAX1BP1	TCP1	CCT8	TMEM173	RNF213	ECSIT	NDUFC2	IST1	HSPA9	IFNA13	IFNA14	IFNA16	IFNA17	TP53	IFNA10	GATA3	ABL1	IFNA21	SOD2	IFNA5	IFNA4	IFNA7	IFNA6	IFNA1	IFNA2	HBB	IFNA8	RAC1	RBSN	IRF1	IRF2	DOCK2	DOCK1	CDC42	IFNB1	ALDH3B1	ORMDL3	DEGS1	PTPN1	SYK	CRK	RAPGEF3	RAPGEF4	PTPRJ	RAB4B	AP2A1	C3AR1	AP2A2	TXNIP	LNPEP	TXN	MEFV	AP2M1	MYLIP	SERPINA1	IL18	NPC2	IL1A	IL1B	SAR1B	VAMP8	VAMP7	VAMP2	AP2S1	APOB	STX4	PYCARD	RAB3A	CYBA	HP	AP2B1	RAB31	GPR84	P4HB	RAB5B	NLRP3	RAB5C	TXNDC5	PSTPIP1	CASP1	TRAPPC1	P2RX7	PPP1CB	POMC	ACTR1A	SUGT1	PPP2R1A	PRKACA	BTRC	MGAM	CEP290	SKP1	HSP90AA1	CHIT1	FBXW11	TUBB	SNAP23	DYNLL1	SEC23A	UBA52	SEC24B	SEC24A	DYNC1I2	DCTN2	RAB10	DCTN3	CUL1	RAB14	UBB	SEC24D	SEC24C	UBC	TBC1D10C	RPS27A	DYNC1H1	MRE11A	TUBB4B	RAB27A	MAOA	CTSZ	GDI2	CXCL8	CTSC	CCL2	HSPA5	CDK13	CDC20	IL10	IL6	IL7R	PRKCSH	BCL6	MAGT1	PIN1	COLEC12	PTEN	DDOST	RNF34	NLRC4	IRAK2	CD81	C4BPA	C4BPB	C8B	C8A	CLU	C8G	CR2	CD46	CPNE1	CPB2	CPNE3	CFH	C5AR2	CFI	C5AR1	DGAT1	CPN2	CPN1	PDZD11	C5	C6	C7	CD19	C9	CFHR2	CFHR1	CFHR4	CFHR3	CFHR5	CSNK2B	SLCO4C1	HSPA6	PLD4	PLA2G6	PLD1	PLD3	PLD2	NEDD4	MKRN1	FRK	SLC44A2	LPCAT1	AGPAT2	PLA2G2A	SDC1	ATG7	GRAP2	LCP2	ARG1	DNAJC5	AHCYL1	CD3G	FCGR3A	FCGR1A	YES1	FGR	FCGR2A	NUP107	NUP188	PPP2R1B	IL1RN	IL36A	NUP214	NUP210	IL18RAP	IL36B	PRKCB	IL1R2	IL36RN	IL36G	IL1F10	IL4	NUP93	TOLLIP	PTPN20	HIST2H3A	PTPN23	IL18BP	IL13	IL1RAPL1	IL1RL2	HIST2H3D	PTPN18	MAP3K3	IL37	HIST2H3C	PTPN13	PTPN14	PTPN9	PTPN5	NUP205	PTPN2	IL18R1	POM121	HIST1H3J	AAAS	NUP160	HIST1H3A	NUP85	CSH1	TPR	PRL	PRLR	HIST1H3F	GHR	HIST1H3G	GH2	NUP88	GH1	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	NUP155	NUP153	CISH	SOCS2	ITK	TXK	TEC	ALOX5	LTA4H	LMNB1	ZBP1	NUP62	TBK1	IRF3	NLRP4	NDC1	SEC13	DTX4	NUP133	NUP50	NUP54	PPP2CA	PPP2CB	MAPK1	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	B4GALT1	HVCN1	ADGRE5	ADGRE3	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	HIF1A	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	PRDX6	PSMA6	PSMA3	PSMA4	PSMA1	GSTP1	PSMA2	PSME3	PSME4	PSME1	PSME2	CARD11	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	BCL10	PSMB10	MALT1	PSMA7	RELA	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	ATOX1	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	REL	NFKBIE	NFKBIB	SUMO1	IDH1	VHL	SOD1	SOCS3	IFNG	IFNGR1	IFNGR2	PTPN6	PRR5	PIAS1	CD86	PDPK1	MAPKAP1	CD80	PIK3R3	PIK3R2	PIK3R1	MTOR	PIK3CA	LCK	AKT2	AKT3	MLST8	CD28	THEM4	AKT1	FUCA1	TRIB3	MAP3K8	FYN	RICTOR	MAP3K14	CCND1	TCIRG1	FTH1	ATP6V1E1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	ATP6V1B2	ATP6V0D1	ATP6V0D2	ATP6V0C	ATP6V1B1	FTL	ATP6V1A	CAND1	ATP6V0A2	ATP6V1H	HMOX1	ATP6V0A4	ATP6V1G3	ATP6V0E2	ATP6V1D	ATP6V1C1	HMOX2	ATP6V1C2	ATP6V0A1	ATP6V1F	LCN2	FBXL5	IFITM3	IFITM1	IFITM2	IFIT5	UBE2L6	IFI35	CCR6	IFI30	IFIT1	IFIT3	IFIT2	HERC5	TRIM29	TRIM25	TRIM26	TRIM21	TRIM22	GBP6	GBP5	GBP7	RSAD2	HLA-B	HLA-C	HLA-F	HLA-G	HLA-E	TRIM17	PDE12	TRIM14	TRIM10	TTR	BST2	TRIM8	TRIM6	TRIM5	TRIM2	TRIM3	ARIH1	SP100	RNASEL	PTAFR	IFI6	FLNA	COL1A2	FLNB	MID1	UBA7	IP6K2	ISG20	XAF1	EIF4G3	EIF4G2	CIITA	EIF4E3	ADAR	OASL	TRIM68	TRIM62	DDX58	PPM1B	OAS1	IRF4	OAS2	OAS3	IRF8	IRF5	USP41	IRF6	EIF4E2	IRF9	SAMHD1	USP18	TRIM46	TRIM48	GBP2	GBP1	CDH1	FCGR1B	GBP4	TRIM45	GBP3	MX2	CAPN1	MX1	TRIM35	PRSS2	TRIM38	ABCE1	TRIM31	TRIM34	ADAM10	ADAM17	ADAM8	PSEN1	PRKCE	NCSTN	ELANE	CTSV	CTSS	ACAA1	MMP25	CTSL	CASP3	SNAP25	CTSK	TIMP2	CTSG	TIMP1	CTSD	CTSB	MMP1	MMP2	MMP3	MMP8	MMP9	CD44	LAMA5	HMHA1	ITGA4	IL1R1	TYK2	IFNAR1	S1PR1	STAT2	ARHGAP9	IMPDH1	IMPDH2	PDCD1	RHOG	RHOF	RHOU	CD8B	
IRE1ALPHA ACTIVATES CHAPERONES%REACTOME DATABASE ID RELEASE 74%381070	IRE1alpha activates chaperones	TSPYL2	DDX11	PLA2G4B	WIPI1	PDIA6	PDIA5	ERN1	CTDSP2	KDELR3	DNAJB11	PREB	CUL7	CXXC1	SHC1	ADD1	EXTL2	EXTL1	LMNA	SSR1	DNAJB9	EXTL3	SULT1A3	SEC31A	ZBTB17	KLHDC3	WFS1	EDEM1	GFPT1	SYVN1	YIF1A	SRPRB	HYOU1	HDGF	TPP1	DNAJC3	ARFGAP1	HSPA5	DCTN1	GOSR2	PPP2R5B	TLN1	GSK3A	ACADVL	FKBP14	SRPR	MYDGF	TATDN2	SERP1	ATP6V0D1	
RIP-MEDIATED NFKB ACTIVATION VIA ZBP1%REACTOME DATABASE ID RELEASE 74%1810476	RIP-mediated NFkB activation via ZBP1	RIPK3	NFKB1	NFKBIA	TICAM1	ZBP1	RIPK1	DHX9	NFKBIB	NFKB2	IKBKB	RELA	TLR3	MYD88	NKIRAS1	NKIRAS2	IKBKG	CHUK	
METABOLISM OF RNA%REACTOME%R-HSA-8953854.4	Metabolism of RNA	CSNK1E	UBA52	CPSF7	UBB	CPSF1	CPSF3	CSTF3	CSTF2	UBC	CPSF2	CSTF2T	WDR33	NUDT21	RPS27A	FIP1L1	CLP1	PCF11	PAPOLA	CSTF1	SYMPK	TP53RK	RPL4	EIF4A2	PPP2R2A	EIF4A1	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	WDR61	RPS14	POLR2A	RPS17	POLR2B	RPS16	POLR2C	RPL18A	RPS19	PRMT5	POLR2D	RPL36AL	RPS18	RPL36	POLR2E	RPL35	POLR2F	RPL38	RPL37	POLR2G	POLR2H	RPS11	RPL39	POLR2I	POLR2J	RPS10	RPS13	POLR2K	RPS12	RPS9	POLR2L	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	YBX1	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	YWHAB	RPLP2	HSPB1	ELAVL1	XPO1	RPL13A	KHSRP	TNPO1	RPS3A	RNMT	DIS3	RPL37A	PRKCD	RPL10	RPL12	RNGTT	YWHAZ	RPL11	XRN1	MAPKAPK2	RPL36A	RPS27L	PABPC1	RPS15A	DCP2	RPL14	ANP32A	RPS3	PARN	ZFP36L1	RPL13	EXOSC7	RPL15	EXOSC6	RPS2	EXOSC5	RPL18	EXOSC4	RPL17	EXOSC9	EIF4E	EXOSC8	EIF4B	EXOSC3	RPL19	EXOSC2	RPL35A	EXOSC1	RPL23A	HSPA8	TNFSF13	MAPK14	MAPK11	DCP1A	EIF4G1	RPL22L1	FAU	RPL26L1	LSM10	LSM11	NXT1	EIF4A3	CASC3	GLE1	MAGOH	NCBP1	NCBP2	THOC1	THOC3	THOC2	THOC5	THOC7	CDC40	SRRM1	THOC6	DDX39A	DDX39B	SARNP	ZC3H11A	SRSF2	SRSF3	SRSF4	SRSF5	SRSF6	SRSF7	SLU7	SRSF9	FYTTD1	LUZP4	RBM8A	POLDIP3	SRSF1	U2AF1	U2AF1L4	NXF1	NXF2	U2AF2	DHX38	SRSF11	CHTOP	UPF3B	MAGOHB	NXF2B	RNPS1	TNKS1BP1	CNOT6L	CNOT10	CNOT4	CNOT7	CNOT1	CNOT11	CNOT2	CNOT3	CNOT8	GTF2F1	GTF2F2	CPSF4	PABPN1	RAN	NUP107	NUP188	LTV1	RRP1	NUP214	FCF1	NUP210	THUMPD1	PWP2	RRP9	IMP3	WDR75	PRKCA	IMP4	CIRH1A	NUP93	XRN2	RRP7A	PDCD11	ERI1	GAR1	WBSCR22	DHX37	PNO1	TBL3	LAS1L	MPHOSPH10	NOL11	NOL12	NAT10	NUP205	WDR46	POM121	WDR43	CCNH	TRMT112	SET	RIOK2	RIOK1	AAAS	UTP14A	UTP14C	WDR36	NUP160	TEX10	NUP85	DIEXF	GNL3	TPR	NHP2L1	NIP7	NUP88	TSR3	HEATR1	NOL9	NOC4L	NOL6	EXOSC10	PES1	RRP36	GTF2H1	UTP6	GTF2H2	NUP155	RIOK3	GTF2H3	UTP3	GTF2H4	WDR18	WDR12	GTF2H5	BYSL	BOP1	TSR1	CDK7	MPHOSPH6	NUP153	RPP30	ERCC3	FBL	RPP38	DIMT1	ERCC2	UTP11L	FTSJ3	EBNA1BP2	MNAT1	DKC1	NCL	NHP2	RPP21	RPP25	NOP2	ISG20L2	EMG1	UTP20	NOP14	RPP40	RCL1	NUP62	NOP10	APOBEC1	RBM28	NDC1	APOBEC3C	DDX49	SEC13	APOBEC2	DDX47	WDR3	APOBEC4	NUP133	NOB1	APOBEC3H	A1CF	PELP1	APOBEC3A	UTP15	APOBEC3B	DDX52	SENP3	UTP18	C1D	NUP50	SKIV2L2	DDX21	BMS1	NUP54	RPP14	DCAF13	NOP56	NOP58	KRR1	PPP2CA	UPF2	ZNF473	NUP43	RAE1	RANBP2	SKIV2L	NUP35	NUPL2	NUP37	PSMD8	PSMD9	ETF1	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	RQCD1	PSMA1	PSMA2	PSME3	PSME4	TRMT10C	PSME1	NSUN4	PSME2	RNMTL1	ELAC2	MTERF4	PSMD10	TFB1M	PSMB11	FTSJ2	PSMD12	KIAA0391	PSMD11	HSD17B10	PSMD14	MRM1	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	DDX6	PSMB1	LSM1	PSMF1	LSM5	SHFM1	LSM4	PSMB8	PATL1	LSM3	GSPT2	PSMB9	EDC3	LSM2	PSMC5	EDC4	GSPT1	POP5	PSMC6	LSM7	POP7	PSMC3	LSM6	POP1	PSMC4	DCP1B	POP4	PSMC1	TSEN54	PSMC2	ALKBH8	QTRTD1	GTPBP3	KIAA1456	TRMU	SNW1	SMG1	SMG9	SMG7	SMG8	SMG5	SMG6	ADARB1	UPF1	NSUN2	NSUN6	C14orf166	URM1	PAIP1	TRMT10A	ADAT1	TRMT1	ADAT2	TRMT6	TSEN2	THG1L	FTSJ1	THADA	WDR4	MTO1	QTRT1	NT5C3B	LAGE3	IGF2BP1	IGF2BP3	IGF2BP2	TPRKB	TRIT1	PNRC2	TRMT61A	TRMT61B	RTCB	TRMT44	METTL1	OSGEP	C2orf49	TRMT13	TRMT11	HBS1L	ZCCHC11	ZBTB8OS	DUS2	CTU2	CTU1	DCPS	XPOT	PUS3	CDKAL1	TRNT1	AKT1	PUS7	ZCCHC6	DDX1	PAN2	PAN3	TSEN15	TTC37	TSEN34	TRDMT1	FAM98B	TGS1	HNRNPU	HNRNPR	CCAR1	SNRPD2	SNRPD1	SNRPD3	SRRM2	AQR	METTL3	CRNKL1	SUPT5H	CD2BP2	SF1	SLBP	DHX9	RNPC3	PCBP1	PCBP2	ZRSR2	PRPF38A	HNRNPL	HNRNPM	HNRNPK	HNRNPF	HNRNPD	HNRNPC	SUGP1	PRPF19	PQBP1	DHX15	DHX16	PRPF40A	GCFC2	HNRNPH1	HNRNPH2	SF3B4	SF3B5	SF3B2	SF3B3	SF3B6	SRRT	SRSF10	SF3B1	SF3A3	TYW5	UPF3A	SF3A1	TYW3	SF3A2	XAB2	TRMT5	PHF5A	TYW1	TRMT12	HNRNPA2B1	LCMT2	PRPF31	PDCD7	CWC25	CWC27	EFTUD2	ADAR	CWC22	SNRNP35	TXNL4A	SNRPN	ZCRB1	WBP11	PRPF4	PRPF6	HNRNPUL1	PRPF3	SNRPG	SNRNP27	PPIE	PPIH	SNRPE	SNRPF	SNRNP25	SNRPC	SNRNP200	SNRPA	SNRPB	DDX5	PRPF8	ZMAT5	FUS	CWC15	CHERP	LSM8	ISY1	DDX46	DDX42	PPWD1	GEMIN2	PHAX	USP39	WDR77	ELAVL2	CLNS1A	PTBP1	SART1	GEMIN4	METTL14	GEMIN5	SNRNP70	GEMIN6	CTNNBL1	GEMIN7	BCAS2	GEMIN8	RBM5	DDX20	SMN2	RBM17	SMN1	BUD31	SNUPN	TFIP11	PLRG1	SYF2	SNRPA1	DNAJC8	RBM22	PRCC	WBP4	DDX23	PUF60	TRA2B	SNRPB2	HNRNPA1	SMNDC1	HNRNPA0	PPIL1	HNRNPA3	WTAP	GPKOW	CDC5L	U2SURP	CNOT6	SNRNP40	SNRNP48	PPIL3	PPIL4	RBMX	PPIL6	EPRS	PPP2R1A	CSNK1D	
TRANSMISSION ACROSS ELECTRICAL SYNAPSES%REACTOME DATABASE ID RELEASE 74%112307	Transmission across Electrical Synapses	GJC1	GJD2	GJA10	PANX1	PANX2	
HDR THROUGH MMEJ (ALT-NHEJ)%REACTOME DATABASE ID RELEASE 74%5685939	HDR through MMEJ (alt-NHEJ)	NBN	XRCC1	LIG3	FEN1	PARP2	RBBP8	MRE11A	PARP1	POLQ	RAD50	
RNA POLYMERASE II PRE-TRANSCRIPTION EVENTS%REACTOME DATABASE ID RELEASE 74%674695	RNA Polymerase II Pre-transcription Events	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	CTDP1	ELL	CCNT1	SUPT4H1	TCEB3	TCEB2	TCEB1	NELFA	NELFCD	TCEB3C	TCEB3CL	TCEB3B	TBP	NELFE	GTF2F1	SUPT16H	GTF2F2	SSRP1	SUPT5H	CDK9	TCEA1	TCEB3CL2	CCNK	NELFB	CDC73	CCNH	CTR9	WDR61	RTF1	POLR2A	POLR2B	POLR2C	NCBP1	POLR2D	LEO1	NCBP2	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	PAF1	POLR2K	POLR2L	GTF2H1	GTF2H2	CCNT2	AFF4	GTF2H3	MLLT1	GTF2H4	MLLT3	SUPT6H	GTF2H5	IWS1	EAF1	GTF2A1	EAF2	CDK7	GTF2A2	GTF2B	ERCC3	TAF9	TAF1L	AK6	ERCC2	GTF2E1	GTF2E2	TAF7L	MNAT1	TAF9B	TAF15	TAF12	TAF13	TAF10	
GLUTAMATE BINDING, ACTIVATION OF AMPA RECEPTORS AND SYNAPTIC PLASTICITY%REACTOME%R-HSA-399721.2	Glutamate binding, activation of AMPA receptors and synaptic plasticity	CACNG8	PRKCB	CAMK2G	CACNG2	PRKCA	CACNG3	CACNG4	GRIP1	MDM2	PRKCG	GRIA1	GRIA2	GRIA3	AP2A1	GRIA4	MYO6	AKAP5	DLG1	DLG4	CAMK2A	EPB41L1	TSPAN7	NSF	CAMK2B	PICK1	CAMK2D	
IKBKB DEFICIENCY CAUSES SCID%REACTOME%R-HSA-5602636.1	IKBKB deficiency causes SCID	IKBKB	IKBKG	CHUK	
ACTIVATED NTRK3 SIGNALS THROUGH PLCG1%REACTOME DATABASE ID RELEASE 74%9034793	Activated NTRK3 signals through PLCG1	PLCG1	NTRK3	NTF3	
GSD XV%REACTOME DATABASE ID RELEASE 74%3814836	GSD XV	GYS1	GYG1	
RESISTANCE OF ERBB2 KD MUTANTS TO TESEVATINIB%REACTOME DATABASE ID RELEASE 74%9665245	Resistance of ERBB2 KD mutants to tesevatinib	ERBB2	HSP90AA1	CDC37	ERBB2IP	
ER QUALITY CONTROL COMPARTMENT (ERQC)%REACTOME%R-HSA-901032.5	ER Quality Control Compartment (ERQC)	RPS27A	UGGT2	RNF185	UGGT1	EDEM3	AMFR	MARCH6	RNF103	TRIM13	UBA52	EDEM2	SEL1L	DERL2	RNF5	OS9	MAN1B1	UBB	EDEM1	SYVN1	UBC	RNF139	
TRNA PROCESSING IN THE NUCLEUS%REACTOME%R-HSA-6784531.5	tRNA processing in the nucleus	RPP40	NUP62	NDC1	ELAC2	SEC13	NUP133	NUP50	NUP54	RPP14	CPSF1	CSTF2	CLP1	POP5	POP7	POP1	CPSF4	POP4	NUP43	TSEN54	RAE1	RANBP2	NUP35	NUPL2	NUP37	RAN	NUP107	NUP188	C14orf166	TSEN2	NUP214	NUP210	NUP93	RTCB	C2orf49	NUP205	POM121	ZBTB8OS	AAAS	NUP160	XPOT	NUP85	TPR	TRNT1	NUP88	DDX1	TSEN15	TSEN34	NUP155	FAM98B	NUP153	RPP30	RPP38	RPP21	RPP25	
TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE%REACTOME%R-HSA-110313.1	Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	POLK	UBA7	VCP	UBA52	RCHY1	POLH	UBB	UBC	RPS27A	UBE2L6	USP10	POLI	USP43	REV1	RFC5	MAD2L2	KIAA0101	REV3L	RFC3	ISG15	PCNA	RPA1	TRIM25	RFC4	RPA2	RFC1	RFC2	POLE4	POLD3	POLD4	RPA3	POLE2	UFD1L	POLD1	NPLOC4	POLE3	SPRTN	POLD2	POLE	
KETONE BODY CATABOLISM%REACTOME%R-HSA-77108.4	Ketone body catabolism	BDH1	OXCT1	OXCT2	ACAT1	
LOSS OF MECP2 BINDING ABILITY TO 5MC-DNA%REACTOME DATABASE ID RELEASE 74%9022538	Loss of MECP2 binding ability to 5mC-DNA	HDAC1	SIN3A	
PROCESSIVE SYNTHESIS ON THE LAGGING STRAND%REACTOME DATABASE ID RELEASE 74%69183	Processive synthesis on the lagging strand	POLA2	DNA2	FEN1	PCNA	RPA1	RPA2	LIG1	POLD3	POLD4	RPA3	POLD1	POLD2	PRIM2	PRIM1	POLA1	
CHOLESTEROL BIOSYNTHESIS%REACTOME%R-HSA-191273.4	Cholesterol biosynthesis	LBR	MVD	IDI1	FDPS	FDFT1	MVK	GGPS1	IDI2	CYP51A1	MSMO1	EBP	PPAPDC2	SC5D	DHCR24	HSD17B7	LSS	DHCR7	HMGCS1	ACAT2	TM7SF2	SQLE	ARV1	NSDHL	PMVK	
TGFBR1 LBD MUTANTS IN CANCER%REACTOME%R-HSA-3656535.1	TGFBR1 LBD Mutants in Cancer	TGFB1	TGFBR1	TGFBR2	FKBP1A	
TACHYKININ RECEPTORS BIND TACHYKININS%REACTOME DATABASE ID RELEASE 74%380095	Tachykinin receptors bind tachykinins	TAC3	TAC1	TACR2	TACR1	TACR3	
DEREGULATED CDK5 TRIGGERS MULTIPLE NEURODEGENERATIVE PATHWAYS IN ALZHEIMER'S DISEASE MODELS%REACTOME DATABASE ID RELEASE 74%8862803	Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	LMNB1	FASLG	CAPNS1	FOXO3	BCL2L11	CAPNS2	CDC25A	CAPN2	CAPN1	CAST	CDK5R1	CDC25C	PRDX2	JUN	PRDX1	SOD2	CDC25B	CDK5	GOLGA2	APP	YWHAE	
DEFENSINS%REACTOME DATABASE ID RELEASE 74%1461973	Defensins	DEFB119	DEFB118	DEFB116	DEFB115	DEFB114	TLR1	DEFB105A	DEFB105B	DEFB113	DEFB112	DEFB110	DEFB106B	DEFB106A	TLR2	DEFB129	DEFB128	DEFB127	DEFB126	DEFB125	DEFB124	DEFB123	DEFB107A	DEFB121	DEFB107B	CCR6	CCR2	DEFB136	DEFB135	DEFB134	DEFB133	DEFB108B	DEFB132	DEFB131	DEFB4A	DEFB4B	PRSS3	CD4	DEFB1	DEFA1B	DEFA6	DEFA4	DEFA5	DEFA3	DEFA1	PRSS2	DEFB103A	DEFB103B	ART1	DEFB104B	DEFB104A	
INTERLEUKIN-12 FAMILY SIGNALING%REACTOME DATABASE ID RELEASE 74%447115	Interleukin-12 family signaling	SNRPA1	RALA	PAK2	CAPZA1	LMNB1	MTAP	JAK1	GSTO1	IL6ST	BOLA2B	PSME2	HNRNPDL	LCP1	RPLP0	SOD2	PDCD4	IL23R	IL27RA	IL12B	IL12A	AIP	IL23A	BOLA2	EBI3	IL27	TCP1	ARF1	CANX	HNRNPF	MIF	JAK2	CDC42	VAMP7	HSPA9	CNN2	SOD1	CA1	PPIA	RAP1B	TYK2	HNRNPA2B1	TALDO1	IFNG	PITPNA	STAT4	P4HB	IL10	GSTA2	STAT1	STAT3	SERPINB2	ANXA2	MSN	CFL1	IL12RB1	IL12RB2	CRLF1	
REGULATION OF MECP2 EXPRESSION AND ACTIVITY%REACTOME DATABASE ID RELEASE 74%9022692	Regulation of MECP2 expression and activity	FOXG1	LBR	CAMK2G	CREB1	TBL1XR1	TNRC6C	MOV10	AGO3	AGO4	AGO1	AGO2	AURKB	TNRC6A	TNRC6B	NCOR2	GPS2	NCOR1	TBL1X	CAMK4	HIPK2	HTT	SIN3A	CAMK2A	PRKACA	HDAC2	HDAC1	HDAC3	CAMK2B	CAMK2D	
PI AND PC TRANSPORT BETWEEN ER AND GOLGI MEMBRANES%REACTOME%R-HSA-1483196.2	PI and PC transport between ER and Golgi membranes	PITPNB	
CELL DEATH SIGNALLING VIA NRAGE, NRIF AND NADE%REACTOME DATABASE ID RELEASE 74%204998	Cell death signalling via NRAGE, NRIF and NADE	SQSTM1	ARHGEF26	MAGED1	NCSTN	ABR	BCL2L11	NGEF	ECT2	ARHGEF33	NGFR	TRAF6	ARHGEF35	UBA52	ARHGEF37	ARHGEF39	ARHGEF38	ITGB3BP	NET1	ARHGEF10L	AATF	SOS1	UBB	AKAP13	CASP3	MCF2L	CASP2	UBC	ARHGEF10	PLEKHG2	MAPK8	TRIO	ARHGEF15	PLEKHG5	RPS27A	ARHGEF17	ARHGEF16	KALRN	ARHGEF19	ARHGEF18	NGF	ARHGEF9	ARHGEF3	ARHGEF4	RAC1	ARHGEF1	ARHGEF2	ARHGEF5	ARHGEF6	VAV1	FGD1	FGD2	GNA13	FGD3	FGD4	VAV3	SOS2	MCF2	VAV2	ARHGEF7	ARHGEF11	ARHGEF12	YWHAE	BAD	RASGRF2	TIAM1	PSEN2	PREX1	ARHGEF40	APH1A	ITSN1	APH1B	TIAM2	NGFRAP1	PSENEN	OBSCN	PSEN1	
DEFECTIVE MAT1A CAUSES METHIONINE ADENOSYLTRANSFERASE DEFICIENCY (MATD)%REACTOME DATABASE ID RELEASE 74%5579024	Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)	MAT1A	
NUCLEOTIDE METABOLISM%REACTOME DATABASE ID RELEASE 74%15869	Nucleotide metabolism	DTYMK	AK1	AK2	GLRX	AK4	AK5	TYMS	AK7	AK8	AK9	GUK1	NUDT13	RRM1	NME2	CTPS2	RRM2B	NME3	CTPS1	NME4	GMPR2	ADK	NME1	DCTD	GMPR	AMPD1	CMPK1	AMPD2	DCTPP1	AMPD3	TXNRD1	DCK	APRT	ADAL	DGUOK	PNP	ENTPD1	HPRT1	ENTPD5	ADA	TXN	PFAS	ATIC	PPAT	TK2	TK1	ADSL	CAD	HDHD1	ADSSL1	UMPS	GART	GMPS	ADSS	LHPP	PAICS	UCKL1	DHODH	UCK2	UCK1	NT5E	GDA	DPYS	NUDT5	NT5C2	DNPH1	TYMP	NT5C	UPP2	NT5M	UPP1	IMPDH1	NUDT16	GPX1	IMPDH2	NUDT15	SAMHD1	XDH	ENTPD2	ENTPD3	AGXT2	CDA	ENTPD4	ENTPD6	ENTPD7	ENTPD8	UPB1	NT5C1A	DPYD	NT5C1B	ADPRM	RRM2	ITPA	TAF9	AK6	
TP53 REGULATES METABOLIC GENES%REACTOME DATABASE ID RELEASE 74%5628897	TP53 Regulates Metabolic Genes	PTEN	TNRC6C	MOV10	AGO3	AGO4	GPX2	AGO1	PRDX2	YWHAB	RRM2B	PRDX1	AGO2	COX5B	GLS2	COX5A	TNRC6A	TNRC6B	YWHAZ	TXNRD1	NDUFA4	COX6C	LRPPRC	TXN	GPI	GLS	MT-CO1	TACO1	TP63	PRKAA1	PRKAA2	COX6A1	DDIT4	PRKAG1	PRKAG2	PRKAG3	COX6B1	RPTOR	COX7A2L	SCO1	SCO2	SLC38A9	PRKAB2	MT-CO2	MT-CO3	TSC2	TSC1	COX19	PRKAB1	COX16	MTOR	AKT2	RRAGA	AKT3	RRAGC	COX18	YWHAE	MLST8	RRAGB	COX11	YWHAQ	COX14	RHEB	AKT1	RRAGD	SFN	LAMTOR2	YWHAH	TIGAR	LAMTOR1	LAMTOR4	SURF1	LAMTOR3	LAMTOR5	SESN3	CYCS	SESN2	YWHAG	G6PD	COX20	COX7B	COX4I1	COX7C	COX8A	TP53	
B-WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION%REACTOME DATABASE ID RELEASE 74%5250924	B-WICH complex positively regulates rRNA expression	HIST2H2AC	H2AFJ	BAZ1B	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	SMARCA5	DDX21	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	TBP	HIST2H4A	HIST2H4B	POLR1C	ACTB	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	SF3B1	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	TAF1D	ZNRD1	HIST1H3A	MYBBP1A	TAF1B	TAF1C	POLR2E	HIST1H3F	TWISTNB	POLR2F	HIST1H3G	TAF1A	HIST1H3H	POLR2H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	CD3EAP	POLR2K	HIST1H3E	POLR2L	GSK3B	H3F3B	HIST1H4K	HIST1H4L	DEK	KAT2B	H3F3A	KAT2A	H2BFS	POLR1A	HIST1H4A	POLR1B	HIST1H4B	HIST1H4H	POLR1E	HIST1H4I	ERCC6	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
SIGNALLING TO P38 VIA RIT AND RIN%REACTOME DATABASE ID RELEASE 74%187706	Signalling to p38 via RIT and RIN	RIT1	RIT2	NGF	NTRK1	BRAF	
DEFECTIVE MMACHC CAUSES METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE CBLC%REACTOME DATABASE ID RELEASE 74%3359474	Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC	MMACHC	
BETA OXIDATION OF MYRISTOYL-COA TO LAUROYL-COA%REACTOME DATABASE ID RELEASE 74%77285	Beta oxidation of myristoyl-CoA to lauroyl-CoA	ACADL	HADHB	HADHA	
DEFECTIVE SFTPA2 CAUSES IPF%REACTOME%R-HSA-5687868.2	Defective SFTPA2 causes IPF	SFTPA2	
CYTOSOLIC SULFONATION OF SMALL MOLECULES%REACTOME%R-HSA-156584.3	Cytosolic sulfonation of small molecules	SULT1B1	SULT1C2	SULT1C4	SULT1E1	TPST2	TPST1	SLC26A2	SLC26A1	SULT6B1	PAPSS1	SULT1A3	PODXL2	SULT4A1	ABHD14B	PAPSS2	SULT1A1	IMPAD1	BPNT1	SULT1A4	SULT1A2	SLC35B3	SLC35B2	SULT2A1	
BIOSYNTHESIS OF DPAN-6 SPMS%REACTOME DATABASE ID RELEASE 74%9025106	Biosynthesis of DPAn-6 SPMs	ALOX15	ALOX12	
RAS PROCESSING%REACTOME%R-HSA-9648002.2	RAS processing	ARL2	PDE6D	USP17L2	PRKG2	ZDHHC9	GOLGA7	ABHD17B	LYPLA1	ABHD17A	KRAS	PRKCQ	NRAS	FNTA	RCE1	FNTB	ICMT	HRAS	BCL2L1	ABHD17C	
TFAP2 (AP-2) FAMILY REGULATES TRANSCRIPTION OF OTHER TRANSCRIPTION FACTORS%REACTOME DATABASE ID RELEASE 74%8866906	TFAP2 (AP-2) family regulates transcription of other transcription factors	CITED2	PITX2	TFAP2A	TFAP2C	
SELENOAMINO ACID METABOLISM%REACTOME DATABASE ID RELEASE 74%2408522	Selenoamino acid metabolism	SECISBP2	UBA52	RPS27A	GNMT	HNMT	EEFSEC	RPL4	RPL5	SEPSECS	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	PAPSS1	RPL9	PSTK	RPL6	RPL7	INMT	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	CBS	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	CTH	RPS8	SCLY	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	NNMT	RPS26	RPS25	AHCY	RPS28	RPS27	RPS29	MAT1A	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	TXNRD1	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	DARS	SARS	EPRS	AIMP1	AIMP2	QARS	KARS	LARS	MARS	RARS	IARS	EEF1E1	PAPSS2	
CLEC7A (DECTIN-1) SIGNALING%REACTOME%R-HSA-5607764.1	CLEC7A (Dectin-1) signaling	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	UBE2D2	PSME3	NFATC1	PSME4	UBE2D1	PSME1	PSME2	CDC34	CARD11	PSMD10	TRAF6	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	UBE2V1	PSMD13	BCL10	PSMB10	MALT1	PSMA7	CUL1	RELA	PSMA8	CLEC7A	PSMB6	PSMB7	UBE2N	PRKCD	PSMB4	UBB	TAB3	PSMB5	TAB2	PSMB2	TAB1	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	AHCYL1	PSMC2	PLCG2	IL1B	UBA3	CASP8	PYCARD	NFATC3	NFATC2	PDPK1	UBE2M	SYK	PPP3CA	PPP3CB	MAP3K14	BTRC	ITPR1	ITPR2	ITPR3	PSMD8	SKP1	IKBKB	NFKB2	PSMD9	PPP3R1	PSMD6	PSMD7	PSMD4	PSMD5	FBXW11	PSMD2	PSMD3	PSMD1	IKBKG	RELB	CARD9	MAP3K7	CHUK	PSMA5	
DEFECTIVE MAN1B1 CAUSES MRT15%REACTOME DATABASE ID RELEASE 74%4793950	Defective MAN1B1 causes MRT15	MAN1B1	
SIGNALLING TO RAS%REACTOME%R-HSA-167044.4	Signalling to RAS	RALA	RALB	NGF	MAPK12	MAPKAPK3	MAPK14	MAPK11	SHC1	NRAS	RALGDS	SOS1	NTRK1	HRAS	MAPKAPK2	MAPK13	SHC2	SHC3	
TOLL LIKE RECEPTOR 9 (TLR9) CASCADE%REACTOME%R-HSA-168138.2	Toll Like Receptor 9 (TLR9) Cascade	RPS6KA1	RIPK2	MAPK3	IRAK4	FOS	CREB1	DUSP4	TRAF6	IRF7	PELI1	UBA52	TLR7	UBE2V1	DUSP6	DUSP7	CUL1	RELA	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	TLR9	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	RBSN	PPP2R1B	MAP2K1	TICAM2	LY96	TICAM1	CD14	TLR4	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	AGER	BTRC	IRAK1	S100A12	PPP2R5D	MAP2K7	PIK3R4	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	EEA1	NKIRAS1	NKIRAS2	PIK3C3	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
PI METABOLISM%REACTOME DATABASE ID RELEASE 74%1483255	PI Metabolism	PTEN	PIP5K1C	TMEM55B	RAB14	RAB5A	BMX	FIG4	VAC14	MTMR2	INPP5D	PIKFYVE	MTMR9	PIK3C2A	MTM1	MTMR7	ARF3	ARF1	PIK3CD	PIK3CB	PIK3CG	PIK3R5	PITPNB	INPPL1	PIK3R6	PIP5K1A	PIP5K1B	PIP4K2A	PIP4K2B	PIP4K2C	SACM1L	MTMR4	SBF1	PTPN13	PIK3R3	PIK3R2	TNFAIP8	PIK3R1	MTMR14	GDE1	SBF2	PIK3CA	PIK3C2G	PIK3C2B	RAB4A	TNFAIP8L1	OCRL	TNFAIP8L3	TNFAIP8L2	ENPP6	PI4K2B	TPTE2	MTMR10	RUFY1	MTMR12	MTMR1	INPP5E	INPP4A	MTMR3	INPP4B	MTMR8	GDPD1	INPP5F	PI4K2A	TPTE	GDPD3	SYNJ2	GDPD5	MTMR6	INPP5J	INPP5K	PLEKHA1	PNPLA7	PIK3R4	PLEKHA5	PLEKHA6	SYNJ1	PLEKHA3	PLEKHA4	PLEKHA8	PI4KB	PNPLA6	PIK3C3	
SCAVENGING BY CLASS A RECEPTORS%REACTOME DATABASE ID RELEASE 74%3000480	Scavenging by Class A Receptors	APOE	APOB	FTL	COL1A1	COL3A1	COL1A2	COLEC12	COLEC11	COL4A2	CALR	HSP90B1	COL4A1	APOA1	MSR1	FTH1	SCGB3A2	MARCO	MASP1	SCARA5	
LYSOSOMAL OLIGOSACCHARIDE CATABOLISM%REACTOME%R-HSA-8853383.1	Lysosomal oligosaccharide catabolism	MAN2B1	MANBA	MAN2B2	MAN2C1	
DEFECTIVE ABCC2 CAUSES DJS%REACTOME DATABASE ID RELEASE 74%5679001	Defective ABCC2 causes DJS	ABCC2	
SEROTONIN RECEPTORS%REACTOME%R-HSA-390666.3	Serotonin receptors	HTR6	HTR1A	HTR7	HTR1B	HTR5A	HTR2B	HTR2C	HTR2A	HTR1E	HTR1F	HTR4	HTR1D	
RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS%REACTOME%R-HSA-8939236.1	RUNX1 regulates transcription of genes involved in differentiation of HSCs	HIST2H2AC	H2AFJ	GATA3	GATA2	GATA1	ITCH	ABL1	UBA52	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	UBB	HIST1H2BN	HIST1H2BM	HIST1H2BO	UBC	HIST1H2BJ	HIST1H2BI	HIST1H2BL	RPS27A	HIST1H2BK	HIST2H4A	HIST2H4B	KMT2A	TP73	TCF12	TAL1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	CBFB	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	LMO1	LMO2	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	YAP1	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	CCNH	H2AFB1	HIST1H3J	HIST1H3A	RUNX1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	H3F3A	CDK7	H2BFS	HIST1H4A	TCF3	SPI1	HIST1H4B	LDB1	HIST1H4H	MYB	HIST1H4I	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
GLYCOGEN STORAGE DISEASES%REACTOME%R-HSA-3229121.2	Glycogen storage diseases	RPS27A	GYS2	EPM2A	G6PC3	UBA52	GAA	GYS1	UBB	PPP1R3C	NHLRC1	GYG2	GYG1	UBC	G6PC	GBE1	
SIGNALING BY ACTIVIN%REACTOME%R-HSA-1502540.2	Signaling by Activin	INHBB	INHBA	FSTL3	DRAP1	ACVR1B	ACVR1C	SMAD4	SMAD2	FOXH1	SMAD3	ACVR2B	ACVR2A	FST	
DISEASES OF HEMOSTASIS%REACTOME%R-HSA-9671793.1	Diseases of hemostasis	TPST2	F10	TPST1	GGCX	VWF	KLKB1	GP1BB	F12	F11	GP1BA	F2	GP5	GP9	F8	F9	SERPING1	
NTF3 ACTIVATES NTRK3 SIGNALING%REACTOME DATABASE ID RELEASE 74%9034013	NTF3 activates NTRK3 signaling	NTRK3	NTF3	
MTF1 ACTIVATES GENE EXPRESSION%REACTOME DATABASE ID RELEASE 74%5660489	MTF1 activates gene expression	MTF1	CSRP1	SNCB	
PLATELET SENSITIZATION BY LDL%REACTOME DATABASE ID RELEASE 74%432142	Platelet sensitization by LDL	PPP2CA	APOB	PPP2CB	PLA2G4A	PTPN11	PPP2R1A	LRP8	PPP2R5E	MAPK14	PPP2R5B	PPP2R5A	FGR	PPP2R5D	PPP2R5C	PTPN6	PPP2R1B	
SMAD4 MH2 DOMAIN MUTANTS IN CANCER%REACTOME%R-HSA-3311021.1	SMAD4 MH2 Domain Mutants in Cancer	SMAD2	SMAD3	SMAD4	
MITOCHONDRIAL TRNA AMINOACYLATION%REACTOME%R-HSA-379726.1	Mitochondrial tRNA aminoacylation	IARS2	TARS2	VARS2	CARS2	EARS2	QARS	KARS	PPA2	GARS	RARS2	AARS2	MARS2	PARS2	DARS2	YARS2	HARS2	WARS2	FARS2	LARS2	SARS2	NARS2	
SIGNALING BY JUXTAMEMBRANE DOMAIN KIT MUTANTS%REACTOME DATABASE ID RELEASE 74%9669935	Signaling by juxtamembrane domain KIT mutants	KIT	
ACETYLATION%REACTOME%R-HSA-156582.1	Acetylation	NAT1	NAT2	
INTRINSIC PATHWAY FOR APOPTOSIS%REACTOME DATABASE ID RELEASE 74%109606	Intrinsic Pathway for Apoptosis	DYNLL1	MAPK3	GZMB	BCL2L11	PPP1R13B	YWHAB	NMT1	YWHAZ	CASP3	MAPK8	MAPK1	AVEN	APAF1	TFDP1	DIABLO	TFDP2	CARD8	APIP	XIAP	UACA	CASP9	CASP7	BAK1	DYNLL2	CASP8	BAX	TP63	TP53BP2	TP73	BBC3	BCL2L1	AKT2	AKT3	YWHAE	BAD	PPP3CC	YWHAQ	AKT1	BCL2	C1QBP	SFN	BID	YWHAH	CDKN2A	CYCS	YWHAG	STAT3	PPP3R1	PMAIP1	BMF	E2F1	TP53	
NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE%REACTOME%R-HSA-181430.2	Norepinephrine Neurotransmitter Release Cycle	SLC22A2	SLC22A1	RIMS1	BZRAP1	UNC13B	RAB3A	PPFIA1	PPFIA4	PPFIA3	PPFIA2	SYT1	CPLX1	MAOA	SLC18A2	STX1A	SNAP25	VAMP2	
TRAF3-DEPENDENT IRF ACTIVATION PATHWAY%REACTOME DATABASE ID RELEASE 74%918233	TRAF3-dependent IRF activation pathway	IFIH1	RNF135	MAVS	SIKE1	TBK1	IRF3	TRAF3	TRIM25	IRF7	DDX58	CREBBP	EP300	IFNB1	IKBKE	
REGULATION OF SIGNALING BY CBL%REACTOME DATABASE ID RELEASE 74%912631	Regulation of signaling by CBL	BLNK	FYN	PIK3CD	YES1	PIK3CB	VAV1	CBL	CRKL	RAPGEF1	LYN	PIK3R3	PIK3R2	HCK	PIK3R1	SYK	PIK3CA	CRK	
HCMV INFECTION%REACTOME%R-HSA-9609646.2	HCMV Infection	VPS37C	DYNC1LI1	VPS37D	DYNLL1	VPS37A	DYNC1LI2	VPS37B	HIST2H2AC	CREB1	SNF8	NUP62	CHMP2B	CHMP2A	CHMP4C	NDC1	CHMP4B	SEC13	NUP133	UBAP1	CHMP3	CHMP4A	CHMP6	CHMP7	HIST2H2BE	DYNC1I2	VPS25	VPS28	HIST4H4	NUP50	NUP54	EZH2	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	TBL1X	SUZ12	HIST2H4A	HIST2H2AB	HIST2H4B	HIST1H2AG	DYNC1H1	HIST1H2AA	NUP43	HIST1H2AM	RAE1	HIST1H2AL	RANBP2	HIST1H2AI	HIST1H2AH	HIST1H2AK	NUP35	HIST2H2BF	HIST3H2A	NUPL2	NUP37	HNRNPK	DYNLL2	TBL1XR1	DAXX	NCOR2	NCOR1	PML	DYNC1I1	EGFR	NFKB1	CBX1	CHMP1A	TRIM28	NUP107	NUP188	HIST1H2AE	HIST1H2AD	HDAC3	HIST3H2BB	CEBPD	HIST1H2AC	HIST1H2AB	NUP214	NUP210	HIST1H2AJ	NUP93	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	ITGB1	HIST1H2BD	HIST1H2BC	NUP205	POM121	HIST1H3J	AAAS	ELK1	NUP160	GPS2	HIST1H3A	NUP85	RBBP4	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	HIST1H3I	RBBP7	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	NUP155	HIST1H4K	HIST1H4L	NUP153	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	TSG101	HIST1H4J	HIST1H4C	HIST1H4D	VPS4A	HIST1H4E	MVB12B	HIST1H4F	EED	MVB12A	VPS36	HIST2H2AA3	HIST2H2AA4	
RETINOID CYCLE DISEASE EVENTS%REACTOME DATABASE ID RELEASE 74%2453864	Retinoid cycle disease events	RBP1	NAPEPLD	RDH5	LRAT	STRA6	ABCA4	OPN1SW	RBP4	OPN1MW	TTR	OPN1LW	RDH12	OPN1MW2	RLBP1	
PURINE CATABOLISM%REACTOME%R-HSA-74259.3	Purine catabolism	GPX1	NUDT16	NT5E	NUDT15	XDH	NT5C1A	NT5C1B	ADPRM	ITPA	GDA	NUDT5	NT5C2	DNPH1	NT5C	PNP	
METABOLISM OF INGESTED MESEO2H INTO MESEH%REACTOME%R-HSA-5263617.2	Metabolism of ingested MeSeO2H into MeSeH	TXNRD1	
INTEGRATION OF PROVIRUS%REACTOME%R-HSA-162592.2	Integration of provirus	KPNA1	PPIA	XRCC6	XRCC5	XRCC4	BANF1	HMGA1	PSIP1	LIG4	
DEFECTIVE PRO-SFTPB CAUSES SMDP1 AND RDS%REACTOME%R-HSA-5688031.2	Defective pro-SFTPB causes SMDP1 and RDS	SFTPB	
RAF MAP KINASE CASCADE%REACTOME%R-HSA-5673001.10	RAF MAP kinase cascade	UBA52	UBB	UBC	RPS27A	PPP2CA	PPP2CB	MAPK1	IRS2	PIK3CB	JAK2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PRKCQ	PSMD14	PSMD13	YWHAB	PSMB10	RASGRP1	PSMA7	RASGRP4	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	IRS1	SRC	FN1	PIK3R2	PIK3R1	PIK3CA	RBX1	ARAF	WDR83	PRKG2	FYN	SYNGAP1	DLG1	GOLGA7	DLG3	ACTN2	DLG4	PAQR3	FLT3LG	FRS2	CAMK2A	FRS3	EREG	BTC	TLN1	PDGFB	TGFA	IQGAP1	RCE1	RALGDS	BRAP	ICMT	BRAF	GRIN2B	PTK2	GRIN2D	PPP5C	ARTN	RGL3	RGL1	RGL2	RET	RAF1	AREG	PEA15	NEFL	JAK3	JAK1	DUSP4	DUSP5	LYPLA1	DUSP2	DUSP1	GFRA1	DUSP8	GFRA3	IL17RD	DUSP9	GFRA2	DUSP6	DUSP7	GFRA4	CNKSR2	APBB1IP	CNKSR1	MRAS	LRRC7	KIT	RAPGEF2	HBEGF	SHOC2	DAB2IP	RANBP9	USP17L2	GRIN1	EPGN	ZDHHC9	KBTBD7	KLB	CSF2	ITGA2B	PEBP1	IL5RA	FGF1	FGF2	FGF3	FGF4	PPP1CC	FGF6	FGF7	FNTA	FGF9	FNTB	NRTN	PDGFRB	PDGFRA	MAP2K1	MAP2K2	HGF	VCL	SHC2	SHC3	CUL3	ARL2	CSF2RB	RASAL1	PHB	RASAL2	RASAL3	CSF2RA	RASGRP3	RAP1B	RAP1A	FGF20	MARK3	FGF23	FGF22	PSPN	IL2	FGF16	ERBB2	IL3	IL5	DLG2	GDNF	PTPRA	FGF19	FGF18	NF1	FGFR4	MAP3K11	BCL2L1	FGF10	FLT3	ITGB3	RASGRF2	RASGRF1	ARRB1	LAMTOR2	ARRB2	DUSP16	SPRED3	LAMTOR3	SPRED2	SPRED1	DUSP10	RASGEF1A	PPP2R5E	KSR1	PPP2R5B	PPP2R5A	PPP2R5D	NRG1	PPP2R5C	KSR2	NRG2	RASA3	NRG3	RASA4	NRG4	RASA1	IL3RA	RASA2	MET	CAMK2B	CAMK2D	ABHD17C	IL2RG	PDE6D	MAPK3	CSK	NCAM1	CAMK2G	ANGPT1	MAPK12	ABHD17B	ABHD17A	IL2RA	IL2RB	KRAS	TEK	SHC1	PTPN7	EGF	PTPN3	EGFR	NRAS	SOS1	HRAS	PPP2R1B	SPTAN1	SPTB	SPTBN4	SPTBN5	SPTA1	SPTBN1	SPTBN2	PPP1CB	FGB	PPP2R1A	FGA	VWF	FGG	
PTK6 EXPRESSION%REACTOME%R-HSA-8849473.1	PTK6 Expression	NR3C1	HIF1A	PELP1	EPAS1	PTK6	
FGFR1C LIGAND BINDING AND ACTIVATION%REACTOME%R-HSA-190373.4	FGFR1c ligand binding and activation	FGF4	FGF6	FGF9	ANOS1	FGF20	FGF1	FGF23	FGF2	
CDC6 ASSOCIATION WITH THE ORC:ORIGIN COMPLEX%REACTOME DATABASE ID RELEASE 74%68689	CDC6 association with the ORC:origin complex	ORC4	ORC6	ORC1	E2F3	ORC3	ORC2	MCM8	CDC6	E2F2	E2F1	ORC5	
DEGRADATION OF GLI1 BY THE PROTEASOME%REACTOME%R-HSA-5610780.1	Degradation of GLI1 by the proteasome	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	ITCH	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	CUL1	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	PRKACG	PRKACB	RBX1	PRKACA	BTRC	PSMD8	SKP1	GLI1	PSMD9	PSMD6	PSMD7	PSMD4	SUFU	PSMD5	PSMD2	PSMD3	PSMD1	NUMB	PSMA5	
SIGNALING BY PLASMA MEMBRANE FGFR1 FUSIONS%REACTOME DATABASE ID RELEASE 74%8853336	Signaling by plasma membrane FGFR1 fusions	FGFR1	BAG4	ERLIN2	
NEUROTRANSMITTER CLEARANCE%REACTOME%R-HSA-112311.4	Neurotransmitter clearance	ACHE	MAOA	SLC22A2	ALDH2	COMT	SLC22A1	SLC6A4	BCHE	LRTOMT	SLC6A3	
INTERLEUKIN-37 SIGNALING%REACTOME DATABASE ID RELEASE 74%9008059	Interleukin-37 signaling	PTPN4	PTPN11	SIGIRR	TBK1	PTPN20	PTPN23	IL18BP	PTPN7	PTPN18	STAT3	SMAD3	IL37	PTPN13	PTPN6	PTPN14	PTPN9	PTPN5	PTPN2	IL18R1	PTPN12	CASP1	
ALPHA-LINOLENIC (OMEGA3) AND LINOLEIC (OMEGA6) ACID METABOLISM%REACTOME DATABASE ID RELEASE 74%2046104	alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	ACOT8	ACSL1	HSD17B4	ELOVL1	FADS2	ACAA1	SCP2	ABCD1	ELOVL5	ELOVL2	ELOVL3	FADS1	
FORMATION OF ANNULAR GAP JUNCTIONS%REACTOME DATABASE ID RELEASE 74%196025	Formation of annular gap junctions	GJA1	DNM1	AP2M1	DNM2	CLTCL1	CLTC	CLTA	DAB2	CLTB	
BETA-OXIDATION OF PRISTANOYL-COA%REACTOME%R-HSA-389887.3	Beta-oxidation of pristanoyl-CoA	ACOT8	AMACR	CRAT	HSD17B4	ACOX2	CROT	ACOX3	ACOXL	
C-TYPE LECTIN RECEPTORS (CLRS)%REACTOME%R-HSA-5621481.1	C-type lectin receptors (CLRs)	PAK3	RAF1	PAK2	NFATC1	UBE2D1	UBA52	CLEC4A	CLEC4C	CLEC4D	CLEC4E	CUL1	CLEC7A	UBB	CLEC6A	UBC	MUCL1	MUC17	MUC5B	MUC3A	RPS27A	MUC5AC	MUC1	MUC7	MUC12	MUC13	MUC15	MUC20	MUC4	MUC21	MUC6	PLCG2	UBA3	NFATC3	NFATC2	UBE2M	SYK	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	UBE2D2	PSME3	PSME4	PSME1	PSME2	CDC34	CARD11	PSMD10	TRAF6	PSMB11	PSMD12	PSMD11	PSMD14	UBE2V1	PSMD13	BCL10	PSMB10	MALT1	PSMA7	NRAS	RELA	LYN	PSMA8	PSMB6	UBE2N	HRAS	PSMB7	PRKCD	TAB3	PSMB4	TAB2	PSMB5	TAB1	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	AHCYL1	PSMC2	IL1B	CASP8	PYCARD	FCER1G	PDPK1	PRKACG	PRKACB	PPP3CA	PPP3CB	FYN	MAP3K14	CLEC10A	PRKACA	BTRC	ITPR1	ITPR2	ITPR3	SKP1	NFKB2	PPP3R1	FBXW11	CREBBP	ICAM2	EP300	ICAM3	RELB	CARD9	PAK1	RPS6KA5	CD209	
P53-DEPENDENT G1 S DNA DAMAGE CHECKPOINT%REACTOME DATABASE ID RELEASE 74%69580	p53-Dependent G1 S DNA damage checkpoint	PSMA6	PSMA3	CDKN1A	PSMA4	CDKN1B	PSMA1	PHF20	PSMA2	CHEK2	PSME3	PSME4	ZNF385A	PSME1	PSME2	PCBP4	PSMD10	MDM2	PSMB11	MDM4	UBA52	PSMD12	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	CCNE2	CCNE1	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CDK2	RFWD2	ATM	CDKN2A	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	TP53	
HDMS DEMETHYLATE HISTONES%REACTOME DATABASE ID RELEASE 74%3214842	HDMs demethylate histones	KDM4B	HIST4H4	KDM4C	HIST2H4A	HIST2H4B	KDM3A	KDM1B	KDM4A	KDM5B	KDM5A	PHF2	KDM5C	KDM6B	KDM5D	PHF8	UTY	KDM2A	KDM2B	ARID5B	JMJD6	KDM3B	KDM4D	MINA	HIST2H3A	HIST2H3D	HIST2H3C	KDM7A	KDM6A	HIST1H3J	HIST1H3A	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	HIST1H4K	HIST1H4L	KDM1A	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	
REGULATION OF TP53 ACTIVITY%REACTOME DATABASE ID RELEASE 74%5633007	Regulation of TP53 Activity	SETD8	UBA52	CCNA2	CCNA1	CDK5	AURKB	AURKA	UBB	UBC	BRCA1	NBN	RPS27A	TOP3A	PPP2CA	SUPT16H	PPP2CB	SSRP1	BLM	RBBP8	RPA1	RPA2	CDK2	MRE11A	CDK5R1	CDK1	RAD50	RPA3	BRIP1	HDAC2	EXO1	HDAC1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	RAD17	RAD1	TP53RK	DNA2	RAD9B	EHMT1	RHNO1	NOC2L	ATR	RAD9A	PIP4K2A	PIP4K2B	PIP4K2C	TP63	PRKAA1	DAXX	PRKAA2	L3MBTL1	MEAF6	PRKAG1	NUAK1	PRKAG2	TP53BP2	PRKAG3	BANP	STK11	ATM	TPX2	PRKAB2	TP73	SETD9	PRKAB1	ING5	ING2	PRMT5	BRD1	PML	SGK1	BRD7	CDKN2A	RFC5	HIPK1	RFC3	POU4F1	POU4F2	HIPK2	RFC4	TTC5	CCNG1	PRDM1	RFC2	USP7	PPP2R5C	TAF9	KAT6A	TAF1L	MAPKAPK5	AK6	SMYD2	TAF7L	TAF9B	TAF15	TAF12	BRPF1	TAF13	TAF10	BRPF3	TAF11	TAF4B	TAF7	TAF6	PHF20	TAF5	CHEK2	JMY	TAF4	CHEK1	PIN1	TAF3	PPP1R13B	ZNF385A	TAF2	DYRK2	TAF1	MDM2	MDM4	PPP1R13L	TMEM55B	RNF34	PLK3	TP53INP1	RFFL	TBP	MAPK14	MAPK11	PPP2R1B	CSNK2A1	CSNK2A2	KAT5	CSNK2B	PRR5	PDPK1	MAPKAP1	EHMT2	CHD4	CHD3	MTOR	AKT2	AKT3	MLST8	RBBP4	AKT1	RBBP7	RICTOR	MTA2	PPP2R1A	MBD3	GATAD2B	MAP2K6	GATAD2A	USP2	EP300	TP53	
FUSION AND UNCOATING OF THE INFLUENZA VIRION%REACTOME DATABASE ID RELEASE 74%168270	Fusion and Uncoating of the Influenza Virion	
SPRY REGULATION OF FGF SIGNALING%REACTOME DATABASE ID RELEASE 74%1295596	Spry regulation of FGF signaling	RPS27A	MAPK3	PPP2CA	PPP2CB	PTPN11	MAPK1	PPP2R1A	UBA52	CBL	MKNK1	BRAF	UBB	SPRY2	UBC	
S45 MUTANTS OF BETA-CATENIN AREN'T PHOSPHORYLATED%REACTOME%R-HSA-5358751.1	S45 mutants of beta-catenin aren't phosphorylated	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	CTNNB1	PPP2R1B	AMER1	AXIN1	APC	
CAMK IV-MEDIATED PHOSPHORYLATION OF CREB%REACTOME%R-HSA-111932.3	CaMK IV-mediated phosphorylation of CREB	KPNA2	CAMK4	CREB1	CAMK2G	CAMKK1	CAMKK2	CAMK2A	CAMK2B	CAMK2D	
OPSINS%REACTOME DATABASE ID RELEASE 74%419771	Opsins	OPN4	OPN3	RRH	OPN5	OPN1SW	OPN1MW	OPN1LW	RHO	OPN1MW2	RGR	
DEFECTIVE SLC35D1 CAUSES SCHNECKENBECKEN DYSPLASIA (SCHBCKD)%REACTOME%R-HSA-5579020.1	Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)	SLC35D1	
TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST%REACTOME DATABASE ID RELEASE 74%6804116	TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	CDKN1A	CDKN1B	ZNF385A	PCBP4	CDK2	CCNA2	CCNA1	CCNE2	CCNE1	E2F7	E2F8	ARID3A	E2F1	TP53	
PEPTIDE CHAIN ELONGATION%REACTOME%R-HSA-156902.2	Peptide chain elongation	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	UBA52	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	RPS27A	RPL13	RPL15	RPS2	RPL18	RPL17	EEF1A1	RPL19	RPL35A	RPL23A	EEF2	RPL22L1	FAU	RPL26L1	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	
INTRACELLULAR METABOLISM OF FATTY ACIDS REGULATES INSULIN SECRETION%REACTOME DATABASE ID RELEASE 74%434313	Intracellular metabolism of fatty acids regulates insulin secretion	ACSL4	ACSL3	CD36	
DNA DAMAGE RECOGNITION IN GG-NER%REACTOME DATABASE ID RELEASE 74%5696394	DNA Damage Recognition in GG-NER	YY1	RUVBL1	NFRKB	INO80C	INO80B	INO80E	UBA52	INO80D	INO80	COPS7B	ACTR5	COPS7A	ACTR8	TFPT	UBB	PARP2	MCRS1	CUL4A	DDB1	UBC	CUL4B	ACTL6A	CETN2	RPS27A	DDB2	RBX1	XPC	RAD23A	RAD23B	COPS4	COPS3	PARP1	COPS6	COPS5	COPS2	ACTB	COPS8	GPS1	
SIGNALING BY PDGFRA EXTRACELLULAR DOMAIN MUTANTS%REACTOME DATABASE ID RELEASE 74%9673770	Signaling by PDGFRA extracellular domain mutants	NRAS	SOS1	HRAS	PIK3R2	PDGFRA	PIK3R1	PIK3CA	STAT1	PIK3CB	STAT3	
SIGNALING BY MRAS-COMPLEX MUTANTS%REACTOME%R-HSA-9660537.1	Signaling by MRAS-complex mutants	SHOC2	PPP1CC	YWHAB	RAF1	PPP1CB	ARAF	BRAF	MRAS	
SARS-COV-2 INFECTION%REACTOME%R-HSA-9694516.1	SARS-CoV-2 Infection	RPN2	PRKCSH	TUSC3	RPN1	MAGT1	GANAB	FUT8	MGAT5	CHMP2B	ST3GAL4	CHMP2A	CHMP4C	MGAT1	CHMP4B	MGAT2	VCP	ST3GAL1	CHMP3	UBA52	ST3GAL2	CHMP4A	ST3GAL3	ST6GAL1	CHMP6	CHMP7	EDEM2	MOGS	DDOST	MGAT4C	DAD1	MGAT4A	MGAT4B	STT3A	MAN1B1	ST6GALNAC3	UBB	CTSL	ST6GALNAC4	MAN2A1	UBC	RPS27A	CANX	RB1	SUMO1	UBE2I	FURIN	VHL	MAP1LC3B	ACE2	TMPRSS2	UVRAG	ZCRB1	PARP16	PARP14	PARP10	PARP6	PARP4	PARP9	PARP8	BECN1	DDX5	GSK3B	PIK3R4	GSK3A	PIK3C3	GALNT1	ST6GALNAC2	
ACTIVATION OF THE AP-1 FAMILY OF TRANSCRIPTION FACTORS%REACTOME%R-HSA-450341.1	Activation of the AP-1 family of transcription factors	JUN	MAPK3	MAPK10	FOS	MAPK1	ATF2	MAPK14	MAPK11	MAPK9	MAPK8	
NONSENSE-MEDIATED DECAY (NMD)%REACTOME%R-HSA-927802.2	Nonsense-Mediated Decay (NMD)	UBA52	RPS27A	PPP2CA	UPF2	UPF3A	RPL4	PPP2R2A	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	EIF4A3	RPS17	CASC3	RPS16	RPL18A	RPS19	MAGOH	RPL36AL	NCBP1	RPS18	NCBP2	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	ETF1	RPL27	RPL26	RPL29	RBM8A	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	UPF3B	RPL3L	MAGOHB	RPS26	RPS25	RPS28	RNPS1	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	PABPC1	RPS27L	RPS15A	RPL14	RPS3	GSPT2	RPL13	RPL15	GSPT1	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	DCP1A	SMG1	EIF4G1	SMG9	SMG7	SMG8	SMG5	SMG6	RPL22L1	UPF1	FAU	RPL26L1	PNRC2	PPP2R1A	
RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES%REACTOME DATABASE ID RELEASE 74%380320	Recruitment of NuMA to mitotic centrosomes	CSNK1E	TUBGCP4	NUMA1	TUBG2	DYNLL1	TUBG1	MZT2B	CKAP5	MZT2A	TUBA4A	NME7	HAUS2	MZT1	HAUS1	AKAP9	CEP63	MAPRE1	SFI1	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	HAUS8	HAUS7	PRKAR2B	CEP70	CEP72	CEP192	PCNT	CEP76	CLASP1	CEP78	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	CEP57	YWHAE	CETN2	CEP164	CCP110	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	NINL	CEP290	YWHAG	CDK5RAP2	OFD1	HSP90AA1	CEP135	TUBB	CEP131	TUBGCP2	HAUS4	HAUS3	CSNK1D	TUBGCP5	HAUS6	TUBGCP6	HAUS5	TUBGCP3	
MECP2 REGULATES TRANSCRIPTION FACTORS%REACTOME%R-HSA-9022707.1	MECP2 regulates transcription factors	MEF2C	PPARG	CREB1	RBFOX1	
REGULATION OF HSF1-MEDIATED HEAT SHOCK RESPONSE%REACTOME DATABASE ID RELEASE 74%3371453	Regulation of HSF1-mediated heat shock response	MAPK3	NUP62	NDC1	SEC13	NUP133	NUP50	NUP54	MAPKAPK2	MAPK1	NUP43	RAE1	RANBP2	RPA1	HSPA8	RPA2	NUP35	NUPL2	NUP37	RPA3	NUP107	NUP188	CCAR2	HSPA9	SIRT1	DNAJC2	DNAJC7	NUP214	NUP210	RPS19BP1	HSPA4L	HSPA14	ATR	HSPA13	DNAJB1	NUP93	BAG5	HSPA5	C11orf73	HSPH1	BAG2	DNAJB6	BAG3	BAG1	HSF1	HSPA1L	ST13	HSPA4	ATM	HSPA6	HSPA2	NUP205	HSPA12A	POM121	HSPA12B	AAAS	NUP160	YWHAE	NUP85	TPR	NUP88	GSK3B	NUP155	BAG4	NUP153	
TYROSINE CATABOLISM%REACTOME DATABASE ID RELEASE 74%8963684	Tyrosine catabolism	FAH	HPD	GSTZ1	HGD	TAT	
DOWNREGULATION OF ERBB2 SIGNALING%REACTOME%R-HSA-8863795.2	Downregulation of ERBB2 signaling	MATK	USP8	RNF41	UBA52	PTPN18	EGF	ERBB2	EGFR	CDC37	STUB1	UBB	PTPN12	UBC	AKT2	AKT3	HBEGF	RPS27A	AKT1	ERBB2IP	EREG	CUL5	BTC	NRG1	NRG2	HSP90AA1	NRG3	NRG4	
ENDOGENOUS STEROLS%REACTOME DATABASE ID RELEASE 74%211976	Endogenous sterols	ARNT	RXRA	CYP1B1	AHRR	CYP51A1	CYP46A1	CYP39A1	CYP27A1	CYP11A1	CYP19A1	POMC	PTGIS	CYP11B2	CYP11B1	CYP21A2	FDX1	FDXR	CYP7B1	AHR	FDX1L	CYP7A1	NCOA1	NCOA2	NR1H4	CYP8B1	ARNT2	CYP4V2	
NEDDYLATION%REACTOME DATABASE ID RELEASE 74%8951664	Neddylation	DDA1	ANKRD9	UBXN7	COMMD2	COMMD1	COMMD6	COMMD7	COMMD4	UBE2D1	SOCS6	COMMD5	DCAF7	SPSB3	CCDC8	SKP2	CUL9	FBXO4	UBA52	UBD	FBXO6	NAE1	WDTC1	CCDC22	COMMD10	FBXW4	DTL	FBXW5	TULP4	FBXW10	DCAF16	FBXW7	CUL1	BTBD1	DCAF17	FEM1C	DCAF10	FBXW9	DCAF11	DCAF13	UBB	FEM1A	FBXW2	FEM1B	BTBD6	NEURL2	UBC	RPS27A	ERCC8	FBXL3	KCTD7	UBA3	CUL4A	DDB1	CUL4B	DDB2	FBXO27	FBXO21	FBXO22	FBXW8	FBXO17	PSMD8	FBXO15	FBXO10	PSMD9	FBXO11	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	FBXO44	PSMD3	HIF1A	FBXO41	PSMD1	FBXO40	FBXO30	FBXO31	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	UBE2D2	PSME4	FBXO32	PSME1	PSME2	PSMD10	PSMB11	CUL7	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	FBXO7	PSMB2	PSMB3	FBXO9	PSMB1	PSMF1	FBXO2	EPAS1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	FBXL8	PSMC1	PSMC2	FBXL4	FBXL7	CUL5	GAN	KLHL2	KLHL3	KLHL9	KLHL5	VHL	FBXW12	UBE2F	SOCS3	ASB13	ASB14	ASB11	RNF7	ASB12	ASB17	ASB18	ASB15	RBX1	ASB16	ASB10	KBTBD13	NEDD8	FBXL22	CAND1	FBXL20	FBXL19	FBXL18	FBXL15	BIRC5	FBXL16	FBXL13	FBXL14	FBXL12	FBXL5	TCEB2	TCEB1	GPR75-ASB3	KBTBD6	KBTBD7	KBTBD8	LMO7	CUL3	LRRC41	SPSB2	SPSB1	SPSB4	HIF3A	RFWD2	UBE2M	ZBTB16	LRR1	CCNF	KEAP1	COMMD9	CUL2	SOCS5	SENP8	COPS7B	COPS7A	COMMD3	UCHL3	WDR5	KLHL41	KCTD6	KLHL42	KLHL11	KLHL13	GPS1	KLHL25	KLHL21	KLHL22	KLHL20	RBBP5	ASB8	ASB9	ASB6	ASB7	ASB4	ASB5	UBE2D3	ASB2	ASB1	WSB1	RBBP7	COPS4	BTRC	COPS3	COPS6	COPS5	SKP1	COPS2	DCAF8	DCAF5	DCAF4	CISH	DCAF6	SOCS2	COPS8	WSB2	OBSL1	FBXW11	DCUN1D5	DCUN1D3	DCUN1D4	DCUN1D1	DCUN1D2	COMMD8	PUM2	
GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%5635851	GLI proteins bind promoters of Hh responsive genes to promote transcription	GLI1	GLI3	GLI2	
DEFECTIVE DHDDS CAUSES RETINITIS PIGMENTOSA 59%REACTOME DATABASE ID RELEASE 74%4755609	Defective DHDDS causes retinitis pigmentosa 59	DHDDS	NUS1	
UNC93B1 DEFICIENCY - HSE%REACTOME%R-HSA-5602415.1	UNC93B1 deficiency - HSE	TLR3	UNC93B1	
NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%2122947	NOTCH1 Intracellular Domain Regulates Transcription	CCNC	HDAC6	TBL1XR1	MAML3	MAMLD1	HDAC4	UBA52	HDAC5	NOTCH1	HDAC8	HDAC9	HDAC7	CDK8	HEY1	CUL1	HEY2	UBB	UBC	NCOR2	NCOR1	TLE4	HDAC10	TLE2	HDAC11	RPS27A	TLE1	NBEA	TBL1X	RBX1	MYC	SNW1	MAML2	MAML1	KAT2B	SKP1	RBPJ	KAT2A	HEYL	HDAC2	HDAC1	CREBBP	HIF1A	EP300	HDAC3	HES1	HES5	
DEFECTIVE SLC3A1 CAUSES CYSTINURIA (CSNU)%REACTOME%R-HSA-5619113.1	Defective SLC3A1 causes cystinuria (CSNU)	SLC7A9	SLC3A1	
NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%2197563	NOTCH2 intracellular domain regulates transcription	MAML2	MAML1	GZMB	FCER2	RBPJ	CREB1	MAML3	MAMLD1	EP300	HES1	HES5	NOTCH2	
GENE AND PROTEIN EXPRESSION BY JAK-STAT SIGNALING AFTER INTERLEUKIN-12 STIMULATION%REACTOME%R-HSA-8950505.3	Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	RALA	SNRPA1	CA1	PAK2	CAPZA1	LMNB1	MTAP	GSTO1	BOLA2B	HNRNPDL	PSME2	PPIA	RAP1B	HNRNPA2B1	LCP1	RPLP0	TALDO1	IFNG	PITPNA	STAT4	SOD2	PDCD4	AIP	BOLA2	IL10	TCP1	ARF1	GSTA2	SERPINB2	ANXA2	MSN	HNRNPF	MIF	CFL1	CDC42	HSPA9	CNN2	SOD1	
PLATELET AGGREGATION (PLUG FORMATION)%REACTOME DATABASE ID RELEASE 74%76009	Platelet Aggregation (Plug Formation)	CSK	SRC	RAP1B	RAP1A	SHC1	RASGRP2	RASGRP1	PDPK1	FN1	SOS1	APBB1IP	PTPN1	SYK	CRK	MPL	RAPGEF3	THPO	BCAR1	ITGB3	RAPGEF4	AKT1	FGB	FGA	ITGA2B	VWF	GP1BB	FGG	TLN1	GP1BA	F2	GP5	ADRA2C	GP9	ADRA2A	PTK2	
RNF MUTANTS SHOW ENHANCED WNT SIGNALING AND PROLIFERATION%REACTOME DATABASE ID RELEASE 74%5340588	RNF mutants show enhanced WNT signaling and proliferation	FZD5	WNT3A	FZD4	FZD6	LRP5	LRP6	FZD8	RNF43	
TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION%REACTOME%R-HSA-948021.2	Transport to the Golgi and subsequent modification	DYNC1LI1	DYNLL1	AREG	DYNC1LI2	SEC22A	B4GALT6	SEC22C	B4GALT4	B4GALT5	SEC23A	KDELR2	KDELR3	SEC13	COPB2	COPA	TMED10	COPB1	SEC24B	SEC24A	DYNC1I2	GRIA1	DCTN2	DCTN3	GORASP1	MAN2A2	MAN2A1	RAB1A	SEC24D	SEC24C	RAB1B	MANEA	USO1	LMAN1L	DYNC1H1	LMAN2L	COPE	ARF3	SCFD1	ARF4	ARF1	CAPZB	MAN1A2	TMED3	TMED2	B4GALT1	MAN1A1	CTSZ	TMED7	TMED9	MIA2	MIA3	COPZ2	ARFGAP3	CTSC	DYNLL2	BET1L	ARFGAP1	COPZ1	ARFGAP2	STX17	COL7A1	SEC23IP	SEC22B	ARF5	DCTN6	TRAPPC2L	NAPA	DCTN5	NAPB	TBC1D20	DCTN1	DCTN4	GOSR2	GOSR1	NAPG	MAN1C1	STX5	YKT6	DYNC1I1	GBF1	ARCN1	TRAPPC6A	CAPZA3	CAPZA1	CAPZA2	TRAPPC6B	TFG	FUT8	MGAT5	ST3GAL4	MGAT1	COPG2	MGAT2	PREB	COPG1	ACTR10	ST6GAL1	MGAT4C	MGAT4A	MGAT4B	SEC31A	LHB	CGA	SERPINA1	GOLGA2	SAR1B	LMAN1	SPTAN1	ANK2	ANK3	LMAN2	ANK1	SPTB	SPTBN4	SPTBN5	TRAPPC10	INS	SPTA1	CD59	CD55	SPTBN1	SPTBN2	TMEM115	GOLGB1	FOLR1	BET1	ANKRD28	TRAPPC2	SEC16B	TRAPPC3	TRAPPC1	TRAPPC4	CHST8	FUCA1	SEC16A	CHST10	TRAPPC5	ACTR1A	FUT3	KDELR1	TRAPPC9	CNIH1	MGAT3	TGFA	F5	ST8SIA6	NSF	CNIH2	COG8	CNIH3	B4GALT2	F8	COG7	B4GALT3	MCFD2	COG6	COG5	COG4	ST8SIA2	PPP6C	COG3	CSNK1D	COG2	PPP6R1	COG1	ST8SIA3	PPP6R3	
ANTIGEN PRESENTATION: FOLDING, ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC%REACTOME%R-HSA-983170.3	Antigen Presentation: Folding, assembly and peptide loading of class I MHC	PDIA3	SEC23A	ERAP2	ERAP1	TAP2	HSPA5	TAP1	CALR	SEC13	HLA-A	B2M	SEC24B	SEC24A	CANX	HLA-B	HLA-C	HLA-F	HLA-G	TAPBP	HLA-E	SEC31A	SAR1B	SEC24D	SEC24C	
HDR THROUGH HOMOLOGOUS RECOMBINATION (HRR) OR SINGLE STRAND ANNEALING (SSA)%REACTOME%R-HSA-5693567.2	HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	POLK	ABL1	UBA52	H2AFX	CCNA2	CCNA1	HIST2H2BE	HIST4H4	MUS81	EME1	EME2	POLH	GEN1	SLX1B	UBB	CLSPN	HIST1H2BN	SPIDR	HIST1H2BM	SLX1A	RTEL1	HIST1H2BO	RAD51AP1	UBC	HIST1H2BJ	HIST1H2BI	SLX4	XRCC2	BRCA1	HIST1H2BL	XRCC3	BRCA2	NBN	PALB2	RPS27A	TOP3A	HIST1H2BK	HIST2H4A	PPP4R2	HIST2H4B	TIPIN	BLM	TIMELESS	PPP4C	RBBP8	RPA1	RPA2	CDK2	MRE11A	HIST3H3	RAD51B	RAD50	RAD51C	RAD51	RPA3	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	RAD52	ERCC4	ERCC1	MDC1	RAD17	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	ATM	UBE2V2	RAD51D	RFC5	RFC3	PCNA	RFC4	RFC1	RFC2	POLE4	POLD3	POLD4	POLE2	POLD1	POLE3	POLD2	POLE	BABAM1	HERC2	UIMC1	WHSC1	CHEK1	RNF168	RNF8	BRCC3	TP53BP1	BRE	FAM175A	SUMO2	PIAS4	UBE2N	SUMO1	UBE2I	HIST3H2BB	SIRT6	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	RNF4	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	
DEFECTIVE B3GALT6 CAUSES EDSP2 AND SEMDJL1%REACTOME DATABASE ID RELEASE 74%4420332	Defective B3GALT6 causes EDSP2 and SEMDJL1	AGRN	GPC1	NCAN	BGN	VCAN	DCN	SDC4	CSPG5	CSPG4	SDC3	GPC3	SDC1	GPC2	B3GALT6	GPC5	HSPG2	GPC4	BCAN	GPC6	SDC2	
ALPK1 SIGNALING PATHWAY%REACTOME%R-HSA-9645460.2	ALPK1 signaling pathway	RPS27A	TIFA	UBB	TAB3	TAB2	TAB1	TRAF6	UBC	UBA52	MAP3K7	ALPK1	
DEFECTIVE LARGE CAUSES MDDGA6 AND MDDGB6%REACTOME%R-HSA-5083627.1	Defective LARGE causes MDDGA6 and MDDGB6	LARGE	B4GAT1	
ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE%REACTOME%R-HSA-5620912.2	Anchoring of the basal body to the plasma membrane	CSNK1E	DYNLL1	TUBG1	CKAP5	TUBA4A	HAUS2	HAUS1	AKAP9	CEP63	MAPRE1	SFI1	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	HAUS8	HAUS7	PRKAR2B	CEP70	CEP72	CEP192	PCNT	CEP76	CLASP1	CEP78	B9D2	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	C2CD3	TCTN3	TCTN2	TCTN1	CEP97	CC2D2A	IQCB1	KIF24	SEPT2	TMEM216	FBF1	TTBK2	TMEM67	NPHP1	NPHP4	MARK4	SCLT1	AHI1	CEP162	CEP83	B9D1	CEP89	CEP57	YWHAE	CETN2	CEP164	RPGRIP1L	CCP110	ACTR1A	PCM1	RAB3IP	TUBA1A	PPP2R1A	CNTRL	CEP250	RAB11A	NEK2	PRKACA	NINL	CEP290	YWHAG	RAB8A	CDK5RAP2	MKS1	OFD1	HSP90AA1	CEP135	TUBB	CEP131	HAUS4	HAUS3	CSNK1D	HAUS6	HAUS5	
TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION%REACTOME DATABASE ID RELEASE 74%8869496	TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	NOP2	HSPD1	MYBL2	NPM1	TFAP2A	
DEGRADATION OF DVL%REACTOME DATABASE ID RELEASE 74%4641258	Degradation of DVL	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	HECW1	CUL3	KLHL12	DACT1	DVL1	DVL2	DVL3	RBX1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
FORMATION OF THE CORNIFIED ENVELOPE%REACTOME%R-HSA-6809371.3	Formation of the cornified envelope	FLG	PI3	JUP	SPRR3	CSTA	PCSK6	LCE1A	CASP14	LCE1B	EVPL	PRSS8	LCE1E	LCE1F	LCE1C	LCE1D	LCE2B	LCE2C	LCE2A	FURIN	KAZN	PERP	LOR	ST14	KLK13	PKP2	KLK14	PKP1	KLK12	PKP4	PKP3	TGM1	DSC1	LCE5A	DSC2	DSC3	TGM5	SPINK6	SPINK5	LCE6A	SPINK9	IVL	CAPNS1	LCE2D	LCE3C	SPRR2E	LCE3D	SPRR2F	LCE3A	SPRR2G	LCE3B	LELP1	LCE3E	CAPN1	KLK5	LCE4A	PPL	DSP	KLK8	DSG1	SPRR2A	SPRR2B	DSG2	SPRR2D	DSG3	DSG4	CDSN	TCHH	LIPJ	SPRR1A	RPTN	CELA2A	LIPN	LIPM	SPRR1B	LIPK	
REVERSE TRANSCRIPTION OF HIV RNA%REACTOME DATABASE ID RELEASE 74%162589	Reverse Transcription of HIV RNA	PPIA	
TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE%REACTOME DATABASE ID RELEASE 74%6803204	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	BID	TP53AIP1	PPP1R13B	BAX	STEAP3	TRIAP1	TP63	BNIP3L	TP53BP2	PRELID1	ATM	TP53INP1	TP73	CREBBP	BBC3	PMAIP1	ZNF420	AIFM2	SLMO1	TP53	
CONJUGATION OF BENZOATE WITH GLYCINE%REACTOME%R-HSA-177135.1	Conjugation of benzoate with glycine	ACSM2B	GLYATL3	GLYATL2	GLYATL1	ACSM1	GLYAT	
RHESUS BLOOD GROUP BIOSYNTHESIS%REACTOME%R-HSA-9037628.1	Rhesus blood group biosynthesis	RHCE	RHD	
PKMTS METHYLATE HISTONE LYSINES%REACTOME%R-HSA-3214841.3	PKMTs methylate histone lysines	SETD8	WHSC1	SETD1B	SETD1A	HIST4H4	RELA	EZH2	PRDM9	WDR5	NFKB1	SUZ12	HIST2H4A	HIST2H4B	MECOM	EHMT1	RBBP5	HIST2H3A	ASH2L	HIST2H3D	HIST2H3C	KMT2D	KMT2A	KMT2C	EHMT2	HIST1H3J	HIST1H3A	RBBP4	SUV39H1	HIST1H3F	HIST1H3G	HIST1H3H	RBBP7	HIST1H3I	HIST1H3B	DPY30	HIST1H3C	AEBP2	HIST1H3D	SUV420H2	KMT2E	HIST1H3E	SUV39H2	SETD2	SETD3	SETD6	HIST1H4K	SETD7	HIST1H4L	SUV420H1	KMT2B	WHSC1L1	ASH1L	DOT1L	NSD1	NFKB2	PRDM16	SMYD3	HIST1H4A	ATF7IP	HIST1H4B	SETDB1	HIST1H4H	SETDB2	HIST1H4I	SMYD2	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	EED	HIST1H4F	
B CELL ACTIVATION%REACTOME%R-HSA-983705.1	B Cell Activation	SH3KBP1	NFATC1	UBA52	CUL1	CD79B	CD79A	UBB	UBC	STIM1	RPS27A	ORAI2	ORAI1	PIK3CD	VAV1	PLCG2	PIK3AP1	PPIA	RASGRP3	NFATC3	NFATC2	SYK	FKBP1A	PSMD8	IKBKB	PSMD9	PSMD6	BLK	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	IGKV2-28	IGKV1-12	PSME1	PSME2	CD22	IGKV3D-20	CARD11	IGKV2D-28	PSMD10	PSMB11	IGKV4-1	PSMD12	PSMD11	PSMD14	PSMD13	IGKV2D-30	BCL10	PSMB10	RASGRP1	MALT1	PSMA7	NRAS	IGKV3-11	RELA	LYN	PSMA8	SOS1	PSMB6	IGKV5-2	HRAS	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	AHCYL1	PSMC2	REL	NFKBIE	TRPC1	NFKBIB	NCK1	BTK	PRKCB	BLNK	DAPP1	CD19	PTPN6	PIK3R1	PPP3CA	PPP3CB	FYN	BTRC	ITPR1	ITPR2	ITPR3	SKP1	PPP3R1	FBXW11	
AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY%REACTOME DATABASE ID RELEASE 74%163680	AMPK inhibits chREBP transcriptional activation activity	STK11	PRKAB2	ADIPOQ	MLXIPL	PRKAA2	ADIPOR1	ADIPOR2	PRKAG2	
DEFECTIVE SLC40A1 CAUSES HEMOCHROMATOSIS 4 (HFE4) (DUODENUM)%REACTOME%R-HSA-5655799.1	Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum)	SLC40A1	HEPH	
AXIN MUTANTS DESTABILIZE THE DESTRUCTION COMPLEX, ACTIVATING WNT SIGNALING%REACTOME%R-HSA-4839735.1	AXIN mutants destabilize the destruction complex, activating WNT signaling	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	PPP2R1B	AMER1	AXIN1	APC	
RHO GTPASES ACTIVATE NADPH OXIDASES%REACTOME%R-HSA-5668599.6	RHO GTPases Activate NADPH Oxidases	MAPK3	PRKCB	PRKCA	MAPK1	PIN1	S100A9	PRKCZ	S100A8	NOX1	CYBA	MAPK14	RAC1	MAPK11	PIK3R4	NCF1	NCF2	NCF4	NOXA1	PRKCD	RAC2	PIK3C3	NOXO1	CYBB	NOX3	
NUCLEAR EVENTS (KINASE AND TRANSCRIPTION FACTOR ACTIVATION)%REACTOME DATABASE ID RELEASE 74%198725	Nuclear Events (kinase and transcription factor activation)	RPS6KA1	MAPK3	ASCL1	FOS	CREB1	FOSB	DUSP4	DNM2	CDK5R2	DUSP6	DUSP7	CDK5	MAPKAPK2	MAPK7	PPP2CA	SRF	PPP2CB	MAPK1	EGR2	MAPK14	MAPK11	CDK5R1	PPP2R1B	MEF2D	NAB1	NAB2	ATF1	CHD4	TCF12	ATF2	REST	ELK1	MEF2A	MEF2C	SGK1	VRK3	PPP2R1A	SH3GL3	PPP2R5D	ARC	TRIB1	TPH1	RRAD	F3	JUNB	EGR1	JUND	EGR3	EGR4	FOSL1	ID2	EP300	ID1	ID4	ID3	RPS6KA3	LYL1	RPS6KA5	RPS6KA2	DUSP3	VGF	
PLATELET ADHESION TO EXPOSED COLLAGEN%REACTOME DATABASE ID RELEASE 74%75892	Platelet Adhesion to exposed collagen	GP6	FYN	FCER1G	VWF	GP1BB	ITGA2	GP1BA	ITGA1	GP5	ITGB1	LYN	GP9	ITGA10	
CDT1 ASSOCIATION WITH THE CDC6:ORC:ORIGIN COMPLEX%REACTOME%R-HSA-68827.2	CDT1 association with the CDC6:ORC:origin complex	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	MCM8	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	ORC5	PSMB8	ORC4	RPS27A	PSMB9	ORC6	ORC1	PSMC5	ORC3	PSMC6	ORC2	PSMC3	CDT1	PSMC4	PSMC1	CDC6	PSMC2	GMNN	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
MPS IV - MORQUIO SYNDROME B%REACTOME%R-HSA-2206308.2	MPS IV - Morquio syndrome B	GLB1	
INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION%REACTOME%R-HSA-140837.8	Intrinsic Pathway of Fibrin Clot Formation	KNG1	SERPINA5	C1QBP	A2M	F10	SERPIND1	VWF	KLKB1	GP1BB	F12	F11	GP1BA	F2	GP5	GP9	F8	F9	SERPINE2	PROC	SERPINC1	SERPING1	PROS1	PRCP	
MAPK1 (ERK2) ACTIVATION%REACTOME%R-HSA-112411.1	MAPK1 (ERK2) activation	IL6	IL6R	MAPK1	PTPN11	JAK2	JAK1	MAP2K2	TYK2	
CERAMIDE SIGNALLING%REACTOME%R-HSA-193681.2	Ceramide signalling	NGF	SMPD2	NGFR	
DEFECTIVE CYP26B1 CAUSES RADIOHUMERAL FUSIONS WITH OTHER SKELETAL AND CRANIOFACIAL ANOMALIES (RHFCA)%REACTOME DATABASE ID RELEASE 74%5579015	Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)	CYP26B1	
VEGFR2 MEDIATED VASCULAR PERMEABILITY%REACTOME%R-HSA-5218920.2	VEGFR2 mediated vascular permeability	PAK3	PAK2	JUP	PRR5	CTNND1	PDPK1	CTNNB1	MAPKAP1	MTOR	CDH5	NOS3	AKT2	AKT3	MLST8	THEM4	AKT1	TRIB3	CAV1	RICTOR	RAC1	CTNNA1	VAV1	HSP90AA1	VAV3	VAV2	PAK1	
SELECTIVE AUTOPHAGY%REACTOME%R-HSA-9663891.2	Selective autophagy	SQSTM1	DYNLL1	DYNC1LI1	DYNC1LI2	MAP1LC3A	FUNDC1	USP30	PEX5	CFTR	MTERF3	NBR1	VCP	UBA52	UBE2V1	TOMM70A	DYNC1I2	TOMM7	TOMM5	TOMM6	UBE2N	UBB	VDAC1	UBC	EPAS1	RPS27A	PCNT	PINK1	ULK1	DYNC1H1	HSPA8	CETN1	PARK7	PARK2	TOMM20	MFN1	MFN2	TOMM22	MAP1LC3B	CSNK2A1	DYNLL2	CSNK2A2	HDAC6	PRKAA2	PRKAG1	PRKAG2	CSNK2B	HSF1	PRKAG3	PLIN3	ATM	PRKAB2	ATG5	PRKAB1	IFT88	ARL13B	ATG12	PLIN2	HSP90AA1	DYNC1I1	TOMM40	
O-LINKED GLYCOSYLATION%REACTOME%R-HSA-5173105.4	O-linked glycosylation	B3GNT4	B3GNT3	B3GNT2	CHST4	B4GALT6	B4GALT5	GCNT1	GCNT3	GCNT4	GCNT7	GALNT7	GALNT6	GALNT5	GALNT4	A4GNT	GALNTL5	GALNTL6	GALNT12	MUCL1	MUC17	MUC5B	MUC3A	MUC5AC	MUC1	MUC7	MUC12	MUC13	MUC15	MUC20	MUC4	MUC21	MUC6	GALNT3	SEMA5A	GALNT2	GALNT1	ST6GALNAC2	ADAMTS16	ADAMTS18	ST3GAL4	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	POFUT2	GYLTL1B	B3GALNT2	POMGNT2	ADAMTS4	POMK	ADAMTS5	ADAMTS1	ST6GALNAC3	ST6GALNAC4	ADAMTS2	ADAMTS3	ADAMTS8	ADAMTS9	ADAMTS14	POMT2	SPON2	THBS1	SEMA5B	SPON1	THSD7B	POMT1	ADAMTSL1	C1GALT1C1	DAG1	ADAMTSL4	ADAMTSL3	ADAMTSL2	THSD7A	ADAMTS6	ADAMTS7	SBSPON	POMGNT1	ADAMTS20	B3GLCT	THBS2	CFP	ADAMTS12	THSD1	ADAMTS10	THSD4	ADAMTS15	ADAMTS13	ADAMTS19	LARGE	ADAMTS17	C1GALT1	B4GAT1	GALNT11	GALNT14	GALNT13	GALNT16	GALNT15	GALNT18	B3GNTL1	GALNT10	GALNT9	GALNT8	B3GNT9	WBSCR17	B3GNT8	B3GNT7	B3GNT6	B3GNT5	
MACROAUTOPHAGY%REACTOME%R-HSA-1632852.8	Macroautophagy	SQSTM1	DYNC1LI1	DYNLL1	DYNC1LI2	CHMP2B	CHMP2A	CHMP4C	CFTR	CHMP4B	VCP	UBA52	CHMP3	CHMP4A	CHMP6	CHMP7	TOMM70A	DYNC1I2	TOMM7	TOMM5	TOMM6	UBB	VDAC1	UBC	RPS27A	PCNT	ULK1	DYNC1H1	CETN1	PARK7	PARK2	MFN1	MFN2	MAP1LC3B	DYNLL2	PRKAA1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	PLIN3	RPTOR	ATM	SLC38A9	PRKAB2	ATG7	TSC2	TSC1	ATG5	PRKAB1	MTMR14	RRAGA	RRAGC	RRAGB	RHEB	RRAGD	LAMTOR2	MTMR3	LAMTOR1	LAMTOR4	LAMTOR3	LAMTOR5	PLIN2	DYNC1I1	PIK3C3	WIPI1	MAP1LC3A	FUNDC1	USP30	PEX5	MTERF3	NBR1	GABARAPL2	UBE2V1	GABARAP	UBE2N	EPAS1	PINK1	ATG3	GABARAPL1	HSPA8	ATG9B	ATG9A	ATG10	ATG14	ATG13	ATG101	ATG16L1	WDR45	MAP1LC3C	RB1CC1	WIPI2	ATG4C	ATG4B	ATG4A	ATG4D	TOMM20	WDR45B	AMBRA1	TOMM22	CSNK2A1	CSNK2A2	HDAC6	CSNK2B	HSF1	UVRAG	MTOR	BECN1	MLST8	IFT88	ARL13B	ATG12	PIK3R4	HSP90AA1	TOMM40	
ORGANIC ANION TRANSPORT%REACTOME DATABASE ID RELEASE 74%561048	Organic anion transport	SLC22A12	SLC22A8	SLC22A7	SLC22A11	SLC22A6	
MITOTIC METAPHASE ANAPHASE TRANSITION%REACTOME%R-HSA-68881.2	Mitotic Metaphase Anaphase Transition	PLK1	FBXO5	
BIOSYNTHESIS OF MARESINS%REACTOME DATABASE ID RELEASE 74%9018682	Biosynthesis of maresins	CYP2C9	EPHX2	CYP2C8	CYP3A4	CYP1A2	CYP2D6	CYP2E1	ALOX5	
POST-TRANSLATIONAL PROTEIN MODIFICATION%REACTOME%R-HSA-597592.7	Post-translational protein modification	DDA1	IFIH1	RNF135	ANKRD9	UBXN7	MAVS	COMMD2	COMMD1	COMMD6	COMMD7	SOCS6	COMMD4	COMMD5	SPSB3	CFTR	CCDC8	VCP	CUL9	UBD	NAE1	WDTC1	CCDC22	COMMD10	DTL	SEL1L	TULP4	DCAF16	DCAF17	FEM1C	DCAF10	DCAF11	FEM1A	FEM1B	NEURL2	MANEA	RNF185	SUZ12	KDM1B	PIGS	CPM	LY6K	APOA1	PIGU	PGAP1	PIGT	PIGO	DERL1	DERL2	PSCA	GPAA1	RNF5	PIGN	PIGP	OS9	PIGZ	PIGW	MSLN	PIGV	PIGY	PRSS21	PIGX	FCGR3B	PRND	TECTA	TECTB	CD52	PLAUR	RTN4RL2	IZUMO1R	ALPPL2	PIGC	DPM1	PIGB	DPM2	DPM3	USP8	NRN1L	CEACAM7	RTN4RL1	PIGA	SMAD4	CD109	CEACAM5	PIGK	LY6D	SPACA4	PIGM	PIGL	PIGG	LY6H	USP33	PIGF	GPLD1	PIGH	LY6E	NRN1	NTM	MFI2	TEX101	LYPD1	LYPD2	LYPD3	LYPD4	THY1	LYPD5	ART3	ART4	OTOA	LY6G6C	LY6G6D	OPCML	NTNG1	NTNG2	NEGR1	CNTN5	LSAMP	GP2	PLET1	BST1	VNN1	VNN2	RAET1G	VNN3	XPNPEP2	LYPD6B	RAET1L	ALPL	CNTN3	CNTN4	MDGA2	ULBP2	FOLR2	RECK	MDGA1	SPRN	MKL1	USP30	POFUT2	GYLTL1B	B3GALNT2	POMGNT2	POMK	APLP2	ADAMTS2	ADAMTS3	SCG3	ADAMTS14	USP10	HSPA8	XRCC4	CUL5	ACTB	CALU	QSOX1	AHSG	SPP2	BGLAP	PROZ	GAS6	ALG2	ALG11	RBX1	TGFA	RCE1	SMC3	ICMT	CDCA8	RAD21	AREG	TNC	STAG1	STAM	STAG2	HGS	RANGAP1	SMC1A	INCENP	BIRC5	DNMT1	STAM2	DNMT3B	AURKB	FBN1	XPC	USP17L2	RAD23A	KBTBD7	IL33	PARK7	PARK2	CUL3	USP15	FGF23	SMURF2	UCHL5	SMAD7	UBE2M	GALNT3	EID3	SPARCL1	HRC	JOSD2	PML	JOSD1	PTRH2	ARRB1	FSTL1	ARRB2	GOLM1	MBD1	ATXN3L	MUL1	ATXN7	PCNA	SP3	BMP15	FOXL2	NSMCE4A	ITIH2	UHRF2	LGALS1	POLB	NSMCE2	NSMCE1	MXRA8	SNX3	ZBED1	B4GALNT2	OTUD7A	CHRDL1	RAB22A	KIN	ENAM	MFGE8	STAMBPL1	VCPIP1	UBE2T	FAM175B	CSF1	UBA2	MYSM1	VCPKMT	RCN1	OTUB1	OTUB2	RUVBL1	RAB40A	CDC25A	RAB40B	NFRKB	RAB40C	HCFC1	INO80C	MDM2	TNIP1	INO80B	SOCS5	MDM4	TNIP3	INO80E	SMC5	INO80D	SMC6	USP17L4	INO80	USP17L5	BAP1	EVA1A	UCHL1	USP17L8	SENP8	ACTR5	CHGB	ACTR8	DDX17	RNF128	UCHL3	FOXK2	ALG10B	FOXK1	TADA2B	NPM1	ZNF131	TFPT	MBD5	WDR48	MBD6	SERPINA10	MCRS1	PRSS23	ASGR1	ADRM1	ASGR2	ASXL1	UBXN1	NGLY1	WDR20	ASXL2	AFP	RNF139	METTL21A	MLEC	NDNL2	UGGT2	USP17L3	UGGT1	KTN1	PDIA3	EDEM3	USP17L1	NUCB1	AMFR	NOTUM	MARCH6	RAD23B	RAB3B	EEF1A1	RNF103	RAB3C	TRIM13	N6AMT2	ENGASE	RAB42	RAB2B	EEF2	IGFBP5	USP5	IGFBP4	USP3	MITF	HIC1	RAB34	FKBP8	STAMBP	AMBN	TMEM132A	TADA3	CYR61	METTL10	MEPE	PTP4A2	METTL22	METTL20	RAB20	RAB25	RAB26	RAB23	EEF2KMT	RAB29	RAB15	RAB19	RAB17	USP17L30	YOD1	UMOD	STC2	ZRANB1	PRMT3	POMT2	TOPORS	SPON2	FAM20C	SEMA5B	VWA1	SPON1	FAM20A	THSD7B	USP17L27	POMT1	USP17L26	C3	USP17L29	ADAMTSL1	USP17L28	C1GALT1C1	USP17L21	C4A	ADAMTSL4	USP17L20	ADAMTSL3	USP17L22	ADAMTSL2	USP17L25	THSD7A	USP17L24	ADAMTS6	USP17L15	ADAMTS7	APP	USP17L18	SBSPON	USP17L17	UBE2D3	USP17L19	POMGNT1	ADAMTS20	USP17L10	B3GLCT	USP17L12	USP17L11	THBS2	CFP	USP17L13	ADAMTS12	SHISA5	THSD1	ALG10	ADAMTS10	SCG2	THSD4	AMELX	ADAMTS15	SAE1	ADAMTS13	USP37	ADAMTS19	SENP5	KDELR1	LARGE	USP47	ADAMTS17	USP48	C1GALT1	USP49	B4GAT1	HSP90B1	USP42	RAB43	USP44	RAB41	SAFB	SENP2	SENP1	AMTN	USP14	AR	USP16	NFKB2	USP12	USP19	USP24	USP25	NSF	USP26	USP4	COG8	B4GALT2	RWDD3	USP2	COG7	B4GALT3	USP20	COG6	USP22	COG5	USP28	COG4	COG3	IKBKE	COG2	COG1	RIPK2	DYNC1LI1	RAB30	DYNC1LI2	RAB36	B4GALT4	KDELR2	KDELR3	DCAF7	TRAF3	COPB2	FBXO4	COPA	FBXO6	TMED10	COPB1	FBXW4	FBXW5	TGOLN2	CYLD	BIRC2	FBXW10	TNFAIP3	FBXW7	OTUD7B	BIRC3	NRIP1	FBXW9	MAN2A2	FBXW2	MAN2A1	NOD1	NOD2	RING1	RAB6A	RAB6B	ACTL6A	RAB39A	USP11	TNIP2	COPE	ARF3	FBXL3	ARF4	ARF1	MEN1	CAPZB	MAN1A2	USP9X	TMED3	TMED2	USP21	MAN1A1	OTULIN	TMED7	TFAP2B	TMED9	TFAP2C	COPZ2	ARFGAP3	DYNLL2	UBA3	BET1L	ARFGAP1	RORA	COPZ1	RAB33B	ARFGAP2	SEC22B	ARF5	CUL4A	DDB1	DCTN6	NAPA	DCTN5	CUL4B	NAPB	DCTN1	DCTN4	GOSR2	GOSR1	NAPG	DMP1	FOXO4	ATXN3	MAN1C1	MATN3	STX5	YKT6	ETFB	DYNC1I1	GALNT2	GALNT1	TAF9B	GBF1	ARCN1	TAF10	CAPZA3	LAMB2	CAPZA1	DNMT3A	CAPZA2	PDIA6	RAB18	FBXO32	RAB9A	COPG2	PREB	COPG1	ACTR10	CUL7	RAB9B	SEC31A	WFS1	EDEM1	GFPT1	SYVN1	TRIM28	L3MBTL2	BMI1	SATB2	ST6GALNAC1	CMAS	MPI	GMPPB	NANP	FPGT	GMPPA	PGM3	GNPNAT1	NANS	NUDT14	ST6GAL2	ALG5	RENBP	DHDDS	MVD	ST6GALNAC5	VDR	ST6GALNAC6	GNE	TSTA3	UAP1	NPL	FUOM	NEU2	NEU3	NEU4	RNF2	GMDS	AMDHD2	NEU1	SLC17A5	ST8SIA4	ST8SIA5	ST3GAL5	ST3GAL6	ST8SIA6	FUK	CTSA	NUS1	PMM1	ST8SIA1	ST8SIA2	GFPT2	CTBP1	SRD5A3	TP53	ST8SIA3	PMM2	DOLK	NAGK	PHC2	GLB1	DOLPP1	PHC1	GATA3	PHC3	CBX5	RAB5A	ZNF350	VCAN	TNKS2	TNKS	SIN3A	ARSB	HDAC2	HDAC1	BARD1	WRN	RAD52	LTBP1	BMP4	RHOA	PGR	RFWD2	TFG	HDAC4	RAB4B	HDAC7	COPS7B	COPS7A	PCSK9	LHB	CGA	SERPINA1	APOA2	TRRAP	APOA5	SAR1B	KCTD6	CBX8	SMAD1	CBX4	CBX2	GPS1	NR4A2	APOE	LMAN1	USP34	APOB	THRB	AXIN2	GPIHBP1	LMAN2	MBTPS1	CHML	APOL1	NR1H2	TRAPPC10	RAB3A	THBS1	NR2C1	RAB32	RAB31	ALB	P4HB	RAB35	RAB38	RAB5B	NLRP3	RAB5C	ANKRD28	TRAPPC2	SEC16B	TRAPPC3	RAB4A	TRAPPC1	CETN2	CCP110	TRAPPC4	SEC16A	ACTR1A	TRAPPC5	TUBA1A	TRAPPC9	COPS4	COPS3	BTRC	COPS6	COPS5	CNIH1	RAB8A	COPS2	SKP1	COPS8	CNIH2	FBXW11	CNIH3	MCFD2	PPP6C	CSNK1D	PPP6R1	PPP6R3	VGF	DYNLL1	SEC22A	SEC22C	SEC23A	RAB21	UBA52	SEC24B	SEC24A	DYNC1I2	DCTN2	RAB10	DCTN3	CUL1	AURKA	RAB14	VDAC3	RAB12	VDAC2	UBB	RAB13	VDAC1	SEC24D	SEC24C	UBC	BRCA1	RPS27A	LMAN1L	BLM	DYNC1H1	LMAN2L	RPA1	SCFD1	TUBB4B	TUBB4A	CDK1	RAB39B	RAB27A	RAB27B	CTSZ	TTLL10	TUBB8P12	MIA2	TPGS1	MDC1	MIA3	TTL	TPGS2	TUBB8	TUBA3E	TUBA1C	CTSC	TUBB6	RAB8B	TUBA1B	TUBB3	IGFBP1	TUBB1	RAB33A	AGTPBP1	LRRC49	DAXX	NICN1	RAB7B	TTLL7	AGBL5	CDC73	STX17	AGBL4	TTLL6	UBE2L3	TTLL5	RNF152	SHPRH	TUBB2B	RAB11B	TTLL4	SEC23IP	PEX2	TUBB2A	RNF40	TTLL3	RNF144A	AGBL1	WAC	TTLL2	UBE2V2	CDC20	VIMP	AGBL3	TTLL1	PRKDC	CTR9	CHM	AGBL2	FUCA2	WDR61	TTLL11	RTF1	TTLL12	TTLL9	UBE2J2	ING2	TRAPPC2L	TTLL8	HLTF	TMEM129	LEO1	TBC1D20	DDB2	IL6	RNF20	UBE2B	PEX10	UBE2A	PEX12	PEX13	PEX14	RNF181	PAF1	RAD18	HIPK2	FBXO27	FBXO21	FBXO22	FBXW8	FBXO17	USP7	FBXO15	FBXO10	IGFBP3	FBXO11	FBXO44	FBXO41	FBXO40	FBXO30	FBXO31	ST6GALNAC2	TRAPPC6A	RPN2	PRKCSH	TUSC3	RPN1	MAGT1	GANAB	TRAPPC6B	FUT8	MGAT5	MAT2B	ST3GAL4	PTEN	MGAT1	MGAT2	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	EDEM2	RABGGTB	RABGGTA	MOGS	DDOST	MGAT4C	DAD1	MGAT4A	TOP2B	SUMO3	MGAT4B	SUMO2	STT3A	PIAS4	MAN1B1	PIAS3	ST6GALNAC3	TOP1	ST6GALNAC4	FBXO7	FBXO9	FBXO2	RPS2	FBXL8	FBXL4	FBXL7	GAN	KLHL2	KLHL3	KLHL9	KLHL5	OTUD5	TOMM20	UBE2Z	FBXW12	UBA6	UBE2F	SLC35A1	UBE2H	SLC35C1	UBE2W	UBA1	SMAD2	UBE2K	SMAD3	TGFB1	TGFBR1	TGFBR2	ASB13	ASB14	ASB11	RNF7	ASB12	ASB17	ASB18	ASB15	ASB16	ASB10	IDE	TDG	RAB7A	ALPI	TRIM27	MGAT3	GALNT11	GALNT14	USP13	GALNT13	RNF146	RAB3D	GALNT16	GALNT15	RAB44	GALNT18	B3GNTL1	OTUD3	GALNT10	GALNT9	GALNT8	RAB37	EP300	B3GNT9	WBSCR17	B3GNT8	B3GNT7	B3GNT6	B3GNT5	B3GNT4	B3GNT3	B3GNT2	CHST4	KBTBD13	B4GALT6	B4GALT5	GCNT1	GCNT3	FBXL22	GCNT4	FBXL20	GCNT7	GALNT7	GALNT6	GALNT5	RAB24	GALNT4	FBXL19	A4GNT	FBXL18	GALNTL5	FBXL15	TOMM70A	GALNTL6	FBXL16	GRIA1	FBXL13	FBXL14	FBXL12	EIF5A	EIF5A2	DHPS	DOHH	CLSPN	GALNT12	MUCL1	OGT	MUC17	GPR75-ASB3	MUC5B	MUC3A	MUC5AC	CST3	MUC1	MUC7	MUC12	HIST2H2AB	MUC13	KBTBD6	MUC15	HIST1H2AG	MUC20	KBTBD8	HIST1H2AA	HIST1H2AM	MUC4	MUC21	HIST1H2AL	HIST1H2AI	LMO7	MUC6	HIST1H2AH	HIST1H2AK	HIST2H2BF	HIST3H2A	GPC3	SATB1	PNPLA2	CAMKMT	LRRC41	SPSB2	SPSB1	SPSB4	UBE2E3	ZBTB16	LRR1	CCNF	KEAP1	COMMD9	BPIFB2	COMMD3	CALR	UBE2G1	UBE2G2	PARP1	DNAJC3	CANX	NUP107	NUP188	KLHL41	GOLGA2	KLHL42	HIST1H2AE	HIST1H2AD	KLHL11	HIST3H2BB	KLHL13	HIST1H2AC	HIST1H2AB	RAB2A	NUP214	KLHL25	NUP210	KLHL21	SPTAN1	KLHL22	HIST1H2AJ	ANK2	KLHL20	ANK3	ANK1	SPTB	NUP93	SPTBN4	SPTBN5	UBE2Q2	INS	SPTA1	HIST1H2BF	CD59	HIST1H2BE	CD55	HIST1H2BH	UBE2R2	SPTBN1	HIST1H2BG	SPTBN2	HIST1H2BB	TMEM115	GOLGB1	FOLR1	HIST1H2BA	BET1	ASB8	HIST1H2BD	ASB9	HIST1H2BC	NUP205	ASB6	POM121	ASB7	CHD3	ASB4	AAAS	ASB5	ASB2	NUP160	ASB1	MTA1	NUP85	TPR	WSB1	NUP88	RNF123	RBBP7	NUP155	HIST1H4K	HIST1H4L	KAT2B	NUP153	KAT2A	CISH	HIST1H4A	SOCS2	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	HIST2H2AC	NUP62	UBE2D1	NDC1	SEC13	NUP133	SKP2	UBE2E1	CCNA2	PPARGC1A	CCNA1	HIST2H2BE	HIST4H4	NUP50	BTBD1	GORASP1	NUP54	DCAF13	HIST1H2BN	NOP58	HIST1H2BM	BTBD6	RAB1A	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	RAB1B	USO1	HIST1H2BK	HIST2H4A	HIST2H4B	UBE2C	NUP43	ERCC8	RAE1	UBE2S	RANBP2	NUP35	NUPL2	NUP37	PPARG	PPARA	B4GALT1	KCTD7	YY1	ANO8	CKAP4	RAB11A	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	HIF1A	PSMD1	AXIN1	IKBKG	APC	MAP3K7	PSMA5	PSMA6	PSMA3	BABAM1	PSMA4	HERC2	PSMA1	UIMC1	PSMA2	PSME3	UBE2D2	PSME4	RNF168	PSME1	PSME2	BRCC3	CDC34	PSMD10	TP53BP1	PSMB11	TRAF6	PSMD12	PSMD11	PSMD14	TOP2A	PSMD13	BRE	BCL10	FAM175A	PSMB10	PSMA7	RELA	PSMA8	PSMB6	PSMB7	UBE2N	PSMB4	PSMB5	PSMB2	TAB1	PSMB3	PSMB1	PSMF1	EPAS1	SHFM1	PSMB8	SDC2	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	HLA-A	NR3C2	SUMO1	DPAGT1	ALG8	NCOA1	ALG9	UBE2I	ALG6	NCOA2	ALG14	ALG3	ESR1	ALG13	ALG12	ALG1	VHL	MPDU1	RFT1	NR5A1	RXRA	TRAF2	RIPK1	SOCS3	PIAS1	FN1	BECN1	CHST8	FUCA1	CHST10	FUT3	UFD1L	CREBBP	NEDD8	CAND1	PENK	CP	TF	FBXL5	IGFBP7	TCEB2	TCEB1	MYC	TRIM25	HNRNPK	HNRNPC	SP100	COL7A1	HIF3A	STS	DPH1	DDX58	DPH2	ARSJ	DPH3	ARSK	ARSH	ARSI	DPH5	ARSF	NCOR2	RRAGA	DPH6	ARSG	DPH7	ARSD	RARA	ARSE	FN3K	USP18	ARSA	FN3KRP	SUMF2	CDKN2A	SUMF1	TPST2	DDX5	TPST1	GGCX	PCGF2	SEMA5A	ADAM10	CDH2	ADAMTS16	FSTL3	CUL2	ADAMTS18	LAMC1	ADAMTS4	ADAMTS5	ADAMTS1	ADRB2	TIMP1	WDR5	ADAMTS8	ADAMTS9	FURIN	SPP1	LAMB1	RBBP5	NR3C1	RHOT1	DAG1	SUDS3	SERPINC1	PROS1	KNG1	FGA	F10	SERPIND1	FGG	F2	DCAF8	F5	DCAF5	F7	DCAF4	DCAF6	WSB2	F8	OBSL1	SIAH2	F9	DCUN1D5	PROC	DCUN1D3	DCUN1D4	DCUN1D1	DCUN1D2	COMMD8	PUM2	
MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS%REACTOME DATABASE ID RELEASE 74%9022702	MECP2 regulates transcription of neuronal ligands	CREB1	DLL1	BDNF	SST	HDAC1	CRH	SIN3A	
SYNTHESIS OF PE%REACTOME%R-HSA-1483213.3	Synthesis of PE	PCYT2	ETNPPL	CHKB	PISD	CHKA	ETNK2	ETNK1	EPT1	PHOSPHO1	LPIN1	LPIN2	LPIN3	CEPT1	
RESPONSE OF EIF2AK1 (HRI) TO HEME DEFICIENCY%REACTOME%R-HSA-9648895.2	Response of EIF2AK1 (HRI) to heme deficiency	EIF2S3	CEBPB	TRIB3	CEBPG	CHAC1	PPP1R15A	ASNS	DDIT3	ATF3	ATF4	ATF5	GRB10	EIF2AK1	EIF2S2	EIF2S1	
MASITINIB-RESISTANT KIT MUTANTS%REACTOME%R-HSA-9669924.1	Masitinib-resistant KIT mutants	KIT	
ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS%REACTOME%R-HSA-2029485.1	Role of phospholipids in phagocytosis	PRKCE	IGKV2-28	IGKV1-12	IGKV3D-20	IGKV2D-28	IGKV4-1	IGKV2D-30	IGHG4	IGKV3-11	PLCG1	IGHG1	IGKV5-2	IGHG2	PIK3R2	PRKCD	PLD4	PIK3R1	SYK	PIK3CA	PLA2G6	PLD1	PLD3	PLD2	AHCYL1	CD3G	PPAPDC1A	PPAPDC1B	FCGR3A	FCGR1A	ITPR1	PIK3CB	ITPR2	FCGR2A	ITPR3	PLCG2	
SURFACTANT METABOLISM%REACTOME%R-HSA-5683826.3	Surfactant metabolism	SLC34A1	GATA6	CSF2RB	ZDHHC2	DMBT1	CSF2RA	LMCD1	NAPSA	CCDC59	PGA3	PGA5	PGA4	CTSH	ADGRF5	SLC34A2	ABCA3	CKAP4	ADORA2A	TTF1	SFTA3	P2RY2	SFTPB	SFTPC	ADORA2B	SFTPD	CECR1	SFTPA2	SFTPA1	ADRA2C	ADRA2A	
EVASION OF ONCOGENE INDUCED SENESCENCE DUE TO P16INK4A DEFECTS%REACTOME%R-HSA-9630750.3	Evasion of Oncogene Induced Senescence Due to p16INK4A Defects	CDK6	CDKN2A	CDK4	
TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM%REACTOME%R-HSA-72202.2	Transport of Mature Transcript to Cytoplasm	SRSF11	CHTOP	UPF3B	MAGOHB	NXF2B	RNPS1	NUP62	NDC1	SEC13	NUP133	NUP50	NUP54	CPSF1	CPSF3	CPSF2	WDR33	FIP1L1	SYMPK	EIF4E	CPSF4	NUP43	RAE1	SLBP	RANBP2	NUP35	NUPL2	NUP37	NUP107	NUP188	NUP214	NUP210	NUP93	NUP205	POM121	NXT1	EIF4A3	AAAS	CASC3	GLE1	NUP160	MAGOH	NCBP1	NUP85	NCBP2	TPR	THOC1	THOC3	THOC2	NUP88	THOC5	THOC7	CDC40	SRRM1	THOC6	DDX39A	DDX39B	SARNP	NUP155	ZC3H11A	SRSF2	SRSF3	SRSF4	SRSF5	SRSF6	SRSF7	SLU7	NUP153	SRSF9	FYTTD1	LUZP4	RBM8A	POLDIP3	SRSF1	U2AF1	U2AF1L4	NXF1	NXF2	U2AF2	DHX38	
DEFECTIVE CHST14 CAUSES EDS, MUSCULOCONTRACTURAL TYPE%REACTOME DATABASE ID RELEASE 74%3595174	Defective CHST14 causes EDS, musculocontractural type	CHST14	BCAN	NCAN	BGN	VCAN	DCN	CSPG5	CSPG4	
PROTEIN-PROTEIN INTERACTIONS AT SYNAPSES%REACTOME DATABASE ID RELEASE 74%6794362	Protein-protein interactions at synapses	NRXN1	SHARPIN	PPFIA1	PPFIA4	PPFIA3	PPFIA2	CASK	GRIA1	LIN7A	LIN7C	LIN7B	STX1A	GRIN2A	GRIA3	GRIA4	GRIN2C	FLOT1	APBA1	FLOT2	GRIN1	DBNL	SIPA1L1	LRRTM3	LRRTM4	LRRTM1	LRRTM2	HOMER3	DLGAP1	DLGAP3	DLGAP2	DLGAP4	PTPRS	IL1RAPL2	SHANK2	SHANK1	RTN3	PTPRF	NLGN3	NTRK3	NLGN1	LRFN3	NLGN2	PTPRD	EPB41	LRFN2	STXBP1	LRFN4	NRXN3	LRFN1	NRXN2	IL1RAPL1	BEGAIN	EPB41L5	SLITRK2	SLITRK1	EPB41L2	SLITRK4	EPB41L3	SLITRK3	DLG2	SLITRK6	SLITRK5	PDLIM5	LRRC4B	NLGN4Y	NLGN4X	HOMER1	HOMER2	SYT7	PPFIBP1	PPFIBP2	SYT12	SYT10	APBA3	APBA2	GRM1	DLG1	DLG3	DLG4	GRM5	SYT2	SYT1	EPB41L1	SYT9	GRIN2B	GRIN2D	
PHASE 0 - RAPID DEPOLARISATION%REACTOME%R-HSA-5576892.2	Phase 0 - rapid depolarisation	CACNG8	CACNB2	SCN4A	SCN4B	CAMK2G	SCN1B	CACNG4	SCN1A	SCN7A	SCN9A	SCN8A	SCN11A	CACNA1C	SCN3B	SCN3A	CAMK2A	CACNG6	CACNG7	CACNA2D2	FGF14	RANGRF	SCN2A	FGF13	SCN2B	FGF12	FGF11	SCN10A	SCN5A	CAMK2B	CAMK2D	CACNB1	
DEFECTIVE ALG8 CAUSES ALG8-CDG (CDG-1H)%REACTOME%R-HSA-4724325.1	Defective ALG8 causes ALG8-CDG (CDG-1h)	ALG8	
HYDROLYSIS OF LPC%REACTOME%R-HSA-1483115.3	Hydrolysis of LPC	PLBD1	PLA2G4D	PLA2G4B	PLA2G4C	PLA2G4A	GPCPD1	PLA2G15	PLA2G4F	
TCF7L2 MUTANTS DON'T BIND CTBP%REACTOME%R-HSA-5339700.2	TCF7L2 mutants don't bind CTBP	CTBP2	TCF7L2	CTBP1	
TANDEM PORE DOMAIN POTASSIUM CHANNELS%REACTOME%R-HSA-1296346.1	Tandem pore domain potassium channels	KCNK9	KCNK4	KCNK10	KCNK13	KCNK16	KCNK1	KCNK6	KCNK17	KCNK2	KCNK7	KCNK18	KCNK3	
LOSS OF FUNCTION OF FBXW7 IN CANCER AND NOTCH1 SIGNALING%REACTOME%R-HSA-2644607.1	Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling	SKP1	RBX1	CUL1	NOTCH1	
SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION%REACTOME%R-HSA-416550.2	Sema4D mediated inhibition of cell attachment and migration	ARHGAP35	RRAS	PLXNB1	SEMA4D	RAC1	MET	RHOA	RND1	
DEPYRIMIDINATION%REACTOME%R-HSA-73928.1	Depyrimidination	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST3H3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	OGG1	TINF2	TERF1	TERF2	NEIL3	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	NEIL2	NEIL1	TDG	MBD4	SMUG1	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	NTHL1	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
ION HOMEOSTASIS%REACTOME%R-HSA-5578775.2	Ion homeostasis	CAMK2G	SLN	STIM1	ORAI2	ORAI1	AHCYL1	TRPC1	ABCC9	KCNJ11	RYR1	RYR2	ATP2A3	ATP2A2	ATP2A1	RYR3	SLC8A3	CLIC2	ATP1B3	ATP1B2	ATP1B1	TRDN	ASPH	ATP1A4	ATP1A3	ATP1A2	ATP1A1	SRI	NOS1	FXYD4	PLN	FXYD3	FXYD2	FXYD1	FXYD7	FXYD6	ATP2B4	ATP2B3	ATP2B2	PRKACA	CAMK2A	ATP2B1	ITPR1	ITPR2	ITPR3	FKBP1B	TNNI3	DMPK	SLC8A1	SLC8A2	CAMK2B	CAMK2D	
PROPIONYL-COA CATABOLISM%REACTOME%R-HSA-71032.2	Propionyl-CoA catabolism	MCEE	PCCA	PCCB	MMAA	MUT	
TNFR1-MEDIATED CERAMIDE PRODUCTION%REACTOME%R-HSA-5626978.1	TNFR1-mediated ceramide production	TNF	NSMAF	SMPD3	TNFRSF1A	SMPD2	GNB2L1	
DEFECTIVE EXT1 CAUSES EXOSTOSES 1, TRPS2 AND CHDS%REACTOME%R-HSA-3656253.3	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	AGRN	GPC1	SDC4	SDC3	GPC3	SDC1	GPC2	GPC5	HSPG2	EXT1	GPC4	EXT2	GPC6	SDC2	
GAP JUNCTION TRAFFICKING AND REGULATION%REACTOME%R-HSA-157858.1	Gap junction trafficking and regulation	GJA1	DNM1	GJA3	DNM2	GJA5	GJA4	GJA9	GJA8	CLTB	GJC1	CLTCL1	GJC2	MYO6	GJB2	GJB1	GJB4	GJB3	GJB6	AP2M1	GJB5	GJB7	CLTC	GJA10	CLTA	DAB2	TJP1	GJD2	GJD4	GJD3	
SLBP INDEPENDENT PROCESSING OF HISTONE PRE-MRNAS%REACTOME DATABASE ID RELEASE 74%111367	SLBP independent Processing of Histone Pre-mRNAs	NCBP2	SNRPE	SNRPF	SNRPD3	ZNF473	SNRPB	SNRPG	LSM10	LSM11	NCBP1	
GPVI-MEDIATED ACTIVATION CASCADE%REACTOME%R-HSA-114604.5	GPVI-mediated activation cascade	GP6	PTPN11	PRKCZ	FCER1G	RHOA	RHOB	PTPN6	PDPK1	LYN	PIK3R3	PIK3R2	PIK3R1	RAC2	SYK	PIK3CA	LCK	LCP2	FYN	RHOG	RAC1	PIK3CB	PIK3CG	VAV1	LAT	PIK3R5	PLCG2	VAV3	CDC42	VAV2	C6orf25	PIK3R6	PDPN	CLEC1B	
MAPK3 (ERK1) ACTIVATION%REACTOME%R-HSA-110056.2	MAPK3 (ERK1) activation	IL6	MAPK3	IL6R	PTPN11	JAK2	JAK1	MAP2K1	TYK2	CDK1	
ACTIVATION OF HOX GENES DURING DIFFERENTIATION%REACTOME DATABASE ID RELEASE 74%5619507	Activation of HOX genes during differentiation	PKNOX1	HIST2H2AC	H2AFJ	AJUBA	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	PBX1	EZH2	HIST1H2BN	CTCF	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	SUZ12	HIST2H4A	HOXA3	HIST2H4B	HOXA2	HOXA1	HOXA4	HOXB4	HOXB3	HOXB2	HOXB1	HOXD1	HOXC4	YY1	PIAS2	HOXD4	HOXD3	RARG	ASH2L	KMT2D	KMT2C	KDM6A	PAX6	POLR2A	POLR2B	NCOR1	POLR2C	POLR2D	RARA	RARB	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	PCGF2	ZNF335	MEIS1	RQCD1	CNOT6	MAFB	PAXIP1	PAGR1	WDR5	EGR2	NCOA6	HIST1H2AE	NCOA3	HIST1H2AD	HDAC3	HIST3H2BB	HIST1H2AC	HIST1H2AB	RXRA	HIST1H2AJ	RBBP5	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	RBBP4	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	RBBP7	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	JUN	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	CREBBP	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	EED	HIST2H2AA3	HIST2H2AA4	
SMAD2 SMAD3:SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION%REACTOME%R-HSA-2173796.1	SMAD2 SMAD3:SMAD4 heterotrimer regulates transcription	CCNK	CCNC	SP1	UBA52	SMAD4	SMAD2	SMAD3	CDK8	RBL1	E2F4	E2F5	SMAD7	UBB	CCNT1	UBC	CDKN2B	RPS27A	MYC	CDK9	TGIF1	WWTR1	TGIF2	CCNT2	SNW1	SERPINE1	MEN1	JUNB	RNF111	TFDP1	HDAC1	ATP1B4	TFDP2	
RELAXIN RECEPTORS%REACTOME%R-HSA-444821.1	Relaxin receptors	RLN2	RXFP4	RLN3	RXFP1	RXFP2	INSL3	RXFP3	INSL5	
RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE DURING HIV INFECTION%REACTOME DATABASE ID RELEASE 74%167160	RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	RNMT	CCNH	RNGTT	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	SUPT5H	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	CDK7	ERCC3	ERCC2	MNAT1	
RESOLUTION OF D-LOOP STRUCTURES THROUGH HOLLIDAY JUNCTION INTERMEDIATES%REACTOME DATABASE ID RELEASE 74%5693568	Resolution of D-loop Structures through Holliday Junction Intermediates	DNA2	KAT5	MUS81	ATM	EME1	EME2	GEN1	SLX1B	SPIDR	SLX1A	RAD51AP1	SLX4	BRCA1	XRCC2	BRCA2	XRCC3	NBN	PALB2	TOP3A	RAD51D	BLM	RBBP8	MRE11A	RAD51B	RAD50	RAD51C	RAD51	BRIP1	EXO1	BARD1	RMI2	WRN	RMI1	
ACTIVATION OF BH3-ONLY PROTEINS%REACTOME%R-HSA-114452.2	Activation of BH3-only proteins	DYNLL1	DYNLL2	BCL2L11	PPP1R13B	TP63	TP53BP2	YWHAB	TP73	YWHAZ	BBC3	AKT2	MAPK8	AKT3	YWHAE	BAD	PPP3CC	YWHAQ	AKT1	BCL2	SFN	BID	YWHAH	YWHAG	PPP3R1	TFDP1	TFDP2	PMAIP1	BMF	E2F1	TP53	
RUNX3 REGULATES BCL2L11 (BIM) TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%8952158	RUNX3 regulates BCL2L11 (BIM) transcription	SMAD3	FOXO3	BCL2L11	RUNX3	SMAD4	
AUTOINTEGRATION RESULTS IN VIRAL DNA CIRCLES%REACTOME%R-HSA-177539.2	Autointegration results in viral DNA circles	BANF1	HMGA1	PSIP1	
U12 DEPENDENT SPLICING%REACTOME%R-HSA-72165.1	U12 Dependent Splicing	DDX23	SNRNP40	SNRNP48	SNRPD2	SNRPD1	SNRPD3	LSM2	GTF2F1	GTF2F2	RNPC3	ZRSR2	SF3B4	SF3B5	SF3B2	SF3B3	SF3B6	SF3B1	PDCD7	EFTUD2	SNRNP35	TXNL4A	ZCRB1	PRPF6	POLR2A	SNRPG	POLR2B	POLR2C	NCBP1	POLR2D	NCBP2	SNRPE	NHP2L1	SNRPF	POLR2E	SNRNP25	POLR2F	SNRNP200	POLR2G	POLR2H	SNRPB	POLR2I	POLR2J	PRPF8	ZMAT5	POLR2K	POLR2L	SRSF2	DDX42	YBX1	SRSF6	SRSF7	SRSF1	
BIOSYNTHESIS OF DHA-DERIVED SPMS%REACTOME%R-HSA-9018677.1	Biosynthesis of DHA-derived SPMs	LTA4H	CYP2C9	PTGS2	CYP2C8	LTC4S	CYP1A2	CYP1A1	CYP2E1	EPHX2	CYP3A4	CYP2D6	GSTM4	ALOX15	HPGD	ALOX12	ALOX5	
RESOLUTION OF AP SITES VIA THE SINGLE-NUCLEOTIDE REPLACEMENT PATHWAY%REACTOME%R-HSA-110381.1	Resolution of AP sites via the single-nucleotide replacement pathway	POLB	APEX1	XRCC1	LIG3	
EVASION OF OXIDATIVE STRESS INDUCED SENESCENCE DUE TO DEFECTIVE P16INK4A BINDING TO CDK4%REACTOME%R-HSA-9632697.2	Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4	CDKN2A	CDK4	
NUCLEAR IMPORT OF REV PROTEIN%REACTOME DATABASE ID RELEASE 74%180746	Nuclear import of Rev protein	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	RCC1	NUP50	NUP205	NUP54	POM121	NPM1	AAAS	NUP160	NUP85	TPR	NUP88	KPNB1	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	RAN	NUP107	NUP153	NUP188	
DEFECTIVE DOLK CAUSES DOLK-CDG (CDG-1M)%REACTOME%R-HSA-4755583.1	Defective DOLK causes DOLK-CDG (CDG-1m)	DOLK	
CLEC7A (DECTIN-1) INDUCES NFAT ACTIVATION%REACTOME%R-HSA-5607763.1	CLEC7A (Dectin-1) induces NFAT activation	ITPR3	PPP3CA	PPP3CB	PPP3R1	NFATC1	AHCYL1	NFATC3	NFATC2	ITPR1	ITPR2	
MAJOR PATHWAY OF RRNA PROCESSING IN THE NUCLEOLUS AND CYTOSOL%REACTOME DATABASE ID RELEASE 74%6791226	Major pathway of rRNA processing in the nucleolus and cytosol	CSNK1E	ISG20L2	EMG1	UTP20	NOP14	RPP40	RCL1	RBM28	DDX49	DDX47	WDR3	UBA52	NOB1	PELP1	UTP15	DDX52	SENP3	UTP18	C1D	SKIV2L2	DDX21	BMS1	RPP14	DCAF13	NOP56	NOP58	KRR1	RPS27A	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	DIS3	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	EXOSC7	RPL13	EXOSC6	RPL15	EXOSC5	RPS2	EXOSC4	RPL18	EXOSC9	RPL17	EXOSC8	EXOSC3	EXOSC2	RPL19	EXOSC1	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	LTV1	RRP1	FCF1	PWP2	RRP9	IMP3	WDR75	IMP4	CIRH1A	XRN2	RRP7A	PDCD11	ERI1	WBSCR22	DHX37	PNO1	TBL3	LAS1L	MPHOSPH10	NOL11	NOL12	WDR46	WDR43	RIOK2	RIOK1	UTP14A	UTP14C	WDR36	TEX10	DIEXF	GNL3	NHP2L1	NIP7	HEATR1	NOL9	NOC4L	NOL6	EXOSC10	PES1	RRP36	UTP6	RIOK3	UTP3	WDR18	WDR12	BYSL	BOP1	TSR1	MPHOSPH6	RPP30	FBL	RPP38	UTP11L	FTSJ3	EBNA1BP2	NCL	CSNK1D	RPP21	RPP25	
VIF-MEDIATED DEGRADATION OF APOBEC3G%REACTOME%R-HSA-180585.1	Vif-mediated degradation of APOBEC3G	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	TCEB2	TCEB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CUL5	RBX1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
NEGATIVE REGULATION OF TCF-DEPENDENT SIGNALING BY DVL-INTERACTING PROTEINS%REACTOME%R-HSA-5368598.2	Negative regulation of TCF-dependent signaling by DVL-interacting proteins	DVL1	DVL2	CCDC88C	DVL3	
FATTY ACIDS%REACTOME DATABASE ID RELEASE 74%211935	Fatty acids	CYP2A7	CYP4A22	CYP4F22	CYP4A11	CYP4F2	CYP4F3	CYP4B1	CYP4F11	CYP2B6	CYP4F8	CYP4F12	CYP2A13	CYP2D6	CYP2F1	CYP2J2	
SMOOTH MUSCLE CONTRACTION%REACTOME DATABASE ID RELEASE 74%445355	Smooth Muscle Contraction	ITGB5	PAK2	MYL12B	MYL6	TRIM72	MYH11	GUCY1B3	DYSF	LMOD1	MYL9	MYL6B	ACTG2	MYLK	CALD1	ANXA6	MYL10	GUCY1A3	GUCY1A2	PXN	CAV3	TPM4	TPM3	TPM2	TPM1	SORBS1	SORBS3	MYLPF	MYL5	ANXA1	MYL7	MYL12A	TLN1	ANXA2	ITGA1	ACTA2	PAK1	VCL	
TETRAHYDROBIOPTERIN (BH4) SYNTHESIS, RECYCLING, SALVAGE AND REGULATION%REACTOME%R-HSA-1474151.5	Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	AKT1	PTS	HSP90AA1	SPR	PRKG2	GCH1	DHFR	NOS3	GCHFR	
ABASIC SUGAR-PHOSPHATE REMOVAL VIA THE SINGLE-NUCLEOTIDE REPLACEMENT PATHWAY%REACTOME DATABASE ID RELEASE 74%73930	Abasic sugar-phosphate removal via the single-nucleotide replacement pathway	POLB	APEX1	
SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR3%REACTOME%R-HSA-1839130.1	Signaling by activated point mutants of FGFR3	FGFR3	FGF4	FGF16	FGF9	FGF18	FGF20	FGF1	FGF23	FGF2	
SYNTHESIS OF DOLICHYL-PHOSPHATE%REACTOME%R-HSA-446199.1	Synthesis of Dolichyl-phosphate	DOLK	DHDDS	MVD	DOLPP1	NUS1	SRD5A3	
SULFUR AMINO ACID METABOLISM%REACTOME%R-HSA-1614635.6	Sulfur amino acid metabolism	MRI1	TSTD1	MTRR	MPST	AHCY	MTAP	ETHE1	MTR	GOT1	GOT2	MAT1A	GADL1	SQRDL	TST	BHMT	ADI1	CBS	CSAD	ADO	ENOPH1	SUOX	BHMT2	SLC25A10	CTH	CDO1	TXN2	APIP	
TRUNCATIONS OF AMER1 DESTABILIZE THE DESTRUCTION COMPLEX%REACTOME%R-HSA-5467348.2	Truncations of AMER1 destabilize the destruction complex	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	PPP2R1B	AMER1	AXIN1	APC	
YAP1- AND WWTR1 (TAZ)-STIMULATED GENE EXPRESSION%REACTOME%R-HSA-2032785.3	YAP1- and WWTR1 (TAZ)-stimulated gene expression	YAP1	NKX2-5	TBX5	GATA4	HIPK1	WWTR1	HIPK2	CTGF	KAT2B	TEAD1	TEAD2	TEAD3	TEAD4	NPPA	
DEFECTIVE AHCY CAUSES HYPERMETHIONINEMIA WITH S-ADENOSYLHOMOCYSTEINE HYDROLASE DEFICIENCY (HMAHCHD)%REACTOME DATABASE ID RELEASE 74%5578997	Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)	AHCY	
DEFECTIVE SLCO1B1 CAUSES HYPERBILIRUBINEMIA, ROTOR TYPE (HBLRR)%REACTOME DATABASE ID RELEASE 74%5619110	Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR)	SLCO1B1	
VPU MEDIATED DEGRADATION OF CD4%REACTOME DATABASE ID RELEASE 74%180534	Vpu mediated degradation of CD4	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CD4	BTRC	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
GAMMA-CARBOXYLATION OF PROTEIN PRECURSORS%REACTOME DATABASE ID RELEASE 74%159740	Gamma-carboxylation of protein precursors	F2	F7	BGLAP	F10	PROZ	F9	GGCX	GAS6	PROC	PROS1	
EGR2 AND SOX10-MEDIATED INITIATION OF SCHWANN CELL MYELINATION%REACTOME DATABASE ID RELEASE 74%9619665	EGR2 and SOX10-mediated initiation of Schwann cell myelination	YAP1	LAMB1	LAMA2	NAB1	NAB2	HMGCR	PRX	CYP51A1	MAG	UTRN	LAMC1	MPZ	DAG1	TEAD1	POU3F1	POU3F2	MBP	DRP2	SCD5	WWTR1	ADGRG6	EGR2	SMARCA4	ADGRV1	SOX10	PMP22	HDAC2	SREBF2	
RESOLUTION OF ABASIC SITES (AP SITES)%REACTOME%R-HSA-73933.1	Resolution of Abasic Sites (AP sites)	MPG	OGG1	XRCC1	LIG3	PARP2	NEIL2	NEIL1	TDG	RFC5	MBD4	RFC3	FEN1	SMUG1	PCNA	RPA1	RFC4	RPA2	RFC1	LIG1	PARG	PARP1	RFC2	PNKP	POLE4	POLD3	ADPRHL2	POLB	POLD4	RPA3	POLE2	POLD1	APEX1	POLE3	POLD2	POLE	NTHL1	
FRS-MEDIATED FGFR3 SIGNALING%REACTOME%R-HSA-5654706.3	FRS-mediated FGFR3 signaling	PTPN11	FRS2	FGF20	FRS3	FGF1	FGF23	FGF2	FGF4	FGF16	NRAS	FGF9	SOS1	HRAS	FGF18	
O2 CO2 EXCHANGE IN ERYTHROCYTES%REACTOME%R-HSA-1480926.2	O2 CO2 exchange in erythrocytes	CA1	RHAG	HBB	HBA2	HBA1	CYB5R1	SLC4A1	AQP1	CYB5R2	CYB5R4	CA2	CA4	CYB5RL	
SYNTHESIS OF LEUKOTRIENES (LT) AND EOXINS (EX)%REACTOME DATABASE ID RELEASE 74%2142691	Synthesis of Leukotrienes (LT) and Eoxins (EX)	LTA4H	CYP4A22	ALOX5AP	LTC4S	ABCC1	PTGR1	GGT1	DPEP2	CYP4F22	DPEP1	DPEP3	CYP4A11	CYP4F2	CYP4F3	GGT5	CYP4B1	CYP4F11	CYP4F8	MAPKAPK2	ALOX15	ALOX5	
RHO GTPASE EFFECTORS%REACTOME DATABASE ID RELEASE 74%195258	RHO GTPase Effectors	DYNC1LI1	DYNLL1	DYNC1LI2	CKAP5	HIST2H2AC	H2AFJ	ZW10	CFTR	MAPRE1	SEC13	NUP133	H2AFZ	H2AFX	PAFAH1B1	H2AFV	HIST2H2BE	DYNC1I2	KLC1	HIST4H4	KLC4	KLC3	KLC2	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	NF2	HIST1H2BI	HIST1H2BL	HIST1H2BK	PPP2CA	KIF18A	HIST2H4A	CLASP1	PPP2CB	HIST2H4B	DYNC1H1	MAPK1	NUP43	RANBP2	NDE1	PLK1	CLIP1	CTNNA1	IQGAP2	NUP37	IQGAP3	MEN1	DYNLL2	CTTN	RHOQ	KIF2A	KIF2C	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	CLASP2	DYNC1I1	DIAPH1	NOX3	CENPE	KIF14	CIT	PRC1	DAAM1	PPP1R12B	SCAI	DIAPH3	PIN1	RPS27	MKL1	FMNL3	FMNL1	FMNL2	YWHAB	XPO1	PRKCD	YWHAZ	MYLK	CYFIP2	NCKAP1	CYFIP1	MAPK14	WIPF1	MAPK11	ARPC1B	WIPF2	ARPC1A	WIPF3	BRK1	WASL	ACTB	ACTG1	NCOA2	NCK1	ACTR3	ACTR2	BTK	WAS	NCKIPSD	NCKAP1L	WASF1	WASF2	WASF3	ROPN1	TAX1BP3	PKN3	ARPC4	GOPC	PKN2	ARPC5	RTKN	BAIAP2	RHPN1	ABI2	RHPN2	ARPC2	PPP1R14A	ARPC3	ABI1	ITGB1	NCF1	PDPK1	NCF2	NCF4	RAC2	CYBB	DLG4	PIK3R4	ERCC6L	ZWILCH	IQGAP1	CASC5	KDM1A	KNTC1	MAD1L1	CDCA8	PTK2	PMF1	SKA1	SKA2	PAK1	DSN1	RCC2	PAK3	NDC80	ZWINT	PAK2	AHCTF1	SGOL2	SGOL1	NUF2	SPDL1	NDEL1	ABL1	NUDC	RANGAP1	INCENP	BIRC5	ITGB3BP	MIS12	CENPA	CTNNB1	AURKB	NSL1	CENPC	LIN7B	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	KLK3	CENPI	TAOK1	KDM4C	CENPK	PKN1	CENPL	CENPM	CENPN	CENPO	B9D2	SRF	CENPP	CENPQ	SPC24	SPC25	RAC1	PPP1CC	CDC42	FLNA	ROCK1	ROCK2	LIMK2	LIMK1	RHOC	RHOA	MYL12B	RHOB	MYL6	MYH9	MYH14	MYH11	MYH10	MYL9	YWHAQ	SFN	YWHAH	CDH1	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	CFL1	PIK3C3	KLK2	MAPK3	CDKN1B	PRKCZ	CDC25C	KTN1	NOX1	NUP107	EVL	PPP2R1B	HIST1H2AE	HIST1H2AD	HIST3H2BB	NOXO1	HIST1H2AC	HIST1H2AB	PRKCB	HIST1H2AJ	PRKCA	HIST2H3A	CYBA	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	DVL1	DVL2	HIST1H2BD	HIST1H2BC	DVL3	NOXA1	H2AFB1	HIST1H3J	NUP160	HIST1H3A	NUP85	YWHAE	HIST1H3F	HIST1H3G	PFN1	PPP1CB	HIST1H3H	PFN2	HIST1H3I	HIST1H3B	PPP2R1A	HIST1H3C	HIST1H3D	RHOG	S100A9	HIST1H3E	S100A8	H3F3B	HIST1H4K	HIST1H4L	RHOD	YWHAG	KIF5B	KIF5A	AR	H3F3A	H2BFS	HIST1H4A	HIST1H4B	PPP1R12A	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
KERATAN SULFATE BIOSYNTHESIS%REACTOME%R-HSA-2022854.1	Keratan sulfate biosynthesis	B3GNT4	B3GNT3	SLC35D2	B3GNT2	CHST1	B4GALT6	CHST5	B4GALT4	B4GALT5	CHST2	ST3GAL4	ST3GAL1	ST3GAL2	ST3GAL3	CHST6	B4GAT1	LUM	OGN	OMD	PRELP	ST3GAL6	KERA	FMOD	B4GALT2	B4GALT1	B4GALT3	B3GNT7	
PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING%REACTOME%R-HSA-8849468.1	PTK6 Regulates Proteins Involved in RNA Processing	SFPQ	KHDRBS1	KHDRBS2	KHDRBS3	PTK6	
ACTIVATED NTRK2 SIGNALS THROUGH PLCG1%REACTOME DATABASE ID RELEASE 74%9026527	Activated NTRK2 signals through PLCG1	BDNF	PLCG1	NTF4	NTRK2	
BASIGIN INTERACTIONS%REACTOME%R-HSA-210991.1	Basigin interactions	SPN	PPIA	ATP1B3	MAG	ATP1B2	ITGA3	ATP1B1	PPIL2	ITGA6	ITGB1	L1CAM	SLC7A9	SLC7A11	SLC16A1	SLC7A10	MMP1	CAV1	SLC7A5	BSG	SLC7A6	SLC7A7	SLC7A8	SLC16A8	SLC16A3	SLC3A2	
PREVENTION OF PHAGOSOMAL-LYSOSOMAL FUSION%REACTOME DATABASE ID RELEASE 74%9636383	Prevention of phagosomal-lysosomal fusion	RPS27A	HGS	UBB	RAB5A	VPS33B	UBC	UBA52	CORO1A	RAB7A	
NEIL3-MEDIATED RESOLUTION OF ICLS%REACTOME DATABASE ID RELEASE 74%9636003	NEIL3-mediated resolution of ICLs	NEIL3	
PTK6 REGULATES CELL CYCLE%REACTOME DATABASE ID RELEASE 74%8849470	PTK6 Regulates Cell Cycle	CCNE1	CDKN1B	CDK2	CCND1	CDK4	PTK6	
INHIBITION OF DNA RECOMBINATION AT TELOMERE%REACTOME%R-HSA-9670095.2	Inhibition of DNA recombination at telomere	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	ATRX	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST3H3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	TINF2	TERF1	TERF2	POT1	TERF2IP	DAXX	HIST1H2BF	ACD	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	H3F3B	HIST1H4K	HIST1H4L	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
INTERLEUKIN-15 SIGNALING%REACTOME DATABASE ID RELEASE 74%8983432	Interleukin-15 signaling	IL2RG	JAK3	JAK1	IL15	STAT5A	STAT5B	IL2RB	GAB2	SHC1	STAT3	SOS1	IL15RA	SOS2	GRB2	
MITOCHONDRIAL TRANSLATION TERMINATION%REACTOME DATABASE ID RELEASE 74%5419276	Mitochondrial translation termination	ICT1	GADD45GIP1	PTCD3	MRPL27	MRPL28	ERAL1	MRPL23	MRPL24	MRPL21	MRPL22	MRPL30	MRPS17	MRPS15	MRPS16	MRPS14	MRPS11	MRPS12	MRPL38	MRPL39	MRPS10	MRPL36	MRPL37	MRPL34	MRPL35	MRPL32	MRPL33	MRPL41	MRPL4	MRPL42	MRPL3	MRPL2	MRPL1	MRPL40	MRPL9	CHCHD1	MRPS28	MRPS26	MRPS27	MRPS24	GFM2	MRPS25	MRPS22	MTRF1L	MRPS23	MRRF	MRPL49	MRPS18B	MRPS2	MRPS18A	MRPL47	MRPL48	MRPS7	MRPL45	MRPS6	MRPL46	MRPL43	MRPS5	MRPS18C	MRPL44	MRPL52	OXA1L	MRPL53	MRPL50	MRPS9	MRPL51	AURKAIP1	DAP3	MRPS35	MRPS36	MRPL18	MRPS33	MRPS34	MRPL19	MRPL16	MRPS31	MRPL17	MRPL14	MRPS30	MRPL15	MRPL12	MRPL13	MRPL57	MRPL10	MRPL54	MRPL11	MRPL55	MRPL20	
COLLAGEN DEGRADATION%REACTOME DATABASE ID RELEASE 74%1442490	Collagen degradation	ELANE	COL9A1	COL9A3	COL9A2	COL18A1	COL14A1	MMP20	CTSL	CTSK	COL16A1	COL12A1	CTSD	CTSB	MMP7	MMP1	COL25A1	MMP2	MMP3	MMP8	MMP9	MMP10	PRSS2	MMP12	MMP11	PHYKPL	MMP14	MMP13	COL23A1	MMP15	ADAM10	MMP19	ADAM17	COL15A1	TMPRSS6	ADAM9	COL17A1	FURIN	COL13A1	COL19A1	COL26A1	
P2Y RECEPTORS%REACTOME%R-HSA-417957.2	P2Y receptors	P2RY11	GPR17	P2RY13	P2RY10	P2RY12	P2RY14	LPAR4	P2RY6	P2RY4	LPAR6	P2RY2	P2RY1	
SLBP DEPENDENT PROCESSING OF REPLICATION-DEPENDENT HISTONE PRE-MRNAS%REACTOME DATABASE ID RELEASE 74%77588	SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	NCBP2	SNRPE	SNRPF	SNRPD3	ZNF473	SNRPB	SLBP	SNRPG	LSM10	LSM11	NCBP1	
XBP1(S) ACTIVATES CHAPERONE GENES%REACTOME DATABASE ID RELEASE 74%381038	XBP1(S) activates chaperone genes	TSPYL2	DDX11	PLA2G4B	WIPI1	PDIA6	PDIA5	ARFGAP1	CTDSP2	KDELR3	DNAJB11	PREB	CUL7	CXXC1	SHC1	ADD1	EXTL2	EXTL1	LMNA	SSR1	DNAJB9	EXTL3	SULT1A3	SEC31A	ZBTB17	KLHDC3	WFS1	EDEM1	GFPT1	SYVN1	YIF1A	SRPRB	HYOU1	HDGF	DCTN1	TPP1	GOSR2	PPP2R5B	DNAJC3	TLN1	GSK3A	ACADVL	FKBP14	SRPR	MYDGF	TATDN2	SERP1	ATP6V0D1	
RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASES%REACTOME%R-HSA-388844.2	Receptor-type tyrosine-protein phosphatases	PTPRS	IL1RAPL2	NTRK3	PTPRF	PTPRD	PPFIA1	PPFIA4	IL1RAPL1	PPFIA3	PPFIA2	SLITRK2	SLITRK1	SLITRK4	SLITRK3	SLITRK6	SLITRK5	LRRC4B	PPFIBP1	PPFIBP2	
AMPLIFICATION OF SIGNAL FROM THE KINETOCHORES%REACTOME%R-HSA-141424.2	Amplification of signal from the kinetochores	RCC2	DYNLL1	DYNC1LI1	NDC80	ZWINT	CKAP5	DYNC1LI2	AHCTF1	SGOL2	ZW10	SGOL1	RPS27	NUF2	MAPRE1	SPDL1	SEC13	NDEL1	NUP133	NUDC	RANGAP1	PAFAH1B1	INCENP	BIRC5	DYNC1I2	ITGB3BP	MIS12	CENPA	XPO1	AURKB	NSL1	CENPC	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	PPP2CA	KIF18A	CENPN	CLASP1	CENPO	PPP2CB	B9D2	CENPP	DYNC1H1	CENPQ	NUP43	SPC24	SPC25	RANBP2	NDE1	PLK1	CLIP1	NUP37	PPP1CC	NUP107	PPP2R1B	DYNLL2	KIF2A	KIF2C	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	NUP160	NUP85	PPP2R1A	CLASP2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	ERCC6L	PPP2R5C	ZWILCH	CASC5	KNTC1	MAD1L1	CDCA8	DYNC1I1	PMF1	SKA1	SKA2	DSN1	CENPE	
EVASION OF ONCOGENE INDUCED SENESCENCE DUE TO DEFECTIVE P16INK4A BINDING TO CDK4 AND CDK6%REACTOME%R-HSA-9630794.2	Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	CDK6	CDKN2A	CDK4	
METABOLISM OF AMINE-DERIVED HORMONES%REACTOME%R-HSA-209776.2	Metabolism of amine-derived hormones	DBH	AANAT	CGA	TPH2	TPH1	DUOX1	TPO	SLC5A5	IYD	DIO1	DIO2	DIO3	DUOX2	PNMT	TSHB	DDC	ASMT	TH	
SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION%REACTOME%R-HSA-427359.2	SIRT1 negatively regulates rRNA expression	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	TBP	HIST2H4A	HIST2H4B	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	SIRT1	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	TAF1D	HIST1H3A	TAF1B	SUV39H1	TAF1C	HIST1H3F	HIST1H3G	RRP8	TAF1A	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING%REACTOME%R-HSA-389958.2	Cooperation of Prefoldin and TriC CCT in actin and tubulin folding	TUBA3E	TUBA1C	TUBA4A	TUBB6	TUBA1B	TUBB3	TUBB1	CCT6B	TUBB2B	TUBB2A	VBP1	TUBA4B	PFDN1	PFDN2	CCT3	PFDN4	PFDN5	CCT2	PFDN6	TUBAL3	CCT7	TUBA1A	CCT6A	TCP1	TUBB4B	TUBA8	CCT8	TUBB4A	CCT5	CCT4	ACTB	
TRANSPORT OF THE SLBP INDEPENDENT MATURE MRNA%REACTOME%R-HSA-159227.2	Transport of the SLBP independent Mature mRNA	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	AAAS	NUP160	NUP85	NCBP1	TPR	NCBP2	NUP88	EIF4E	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	NUP107	NUP153	NUP188	NXF1	
DEFECTIVE FACTOR XII CAUSES HEREDITARY ANGIOEDEMA%REACTOME%R-HSA-9657688.1	Defective factor XII causes hereditary angioedema	F2	KLKB1	F12	
IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON-LYMPHOID CELL%REACTOME DATABASE ID RELEASE 74%198933	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	KLRD1	ICAM4	ICAM5	ICAM1	ITGB7	CLEC4G	VCAM1	CD160	SH2D1A	SH2D1B	RAET1E	IFITM1	LAIR2	LAIR1	CLEC2B	CLEC2D	SIGLEC12	SIGLEC11	SIGLEC10	HLA-B	HLA-C	HLA-F	HLA-G	HLA-E	LILRA6	LILRA1	LILRA2	LILRA3	LILRA4	LILRA5	NCR3LG1	LILRB1	LILRB2	LILRB3	LILRB4	LILRB5	CD300A	KLRF1	CD300C	KLRB1	KLRC1	ULBP1	ULBP3	CD40LG	KLRG1	TREML1	TREML4	TREML2	SIGLEC9	HCST	KIR3DL1	KIR3DL2	SIGLEC1	SIGLEC8	CDH1	SIGLEC7	FCGR2B	SIGLEC6	SIGLEC5	CD1D	CD1C	CD1B	CD1A	SLAMF7	SLAMF6	PILRB	PILRA	PIANP	IGKV2-28	IGKV1-12	CD22	IGKV3D-20	COLEC12	IGKV2D-28	IGKV4-1	IGKV2D-30	ITGAL	CD33	IGKV3-11	NCR1	NCR3	IGKV5-2	PVR	TREM2	CD226	MICA	MICB	NPDC1	CD3G	CD200	HLA-A	FCGR3A	B2M	FCGR1A	CXADR	CD96	CD81	CD3E	CD3D	OSCAR	CD8A	KIR2DL1	KIR2DL2	KIR2DL3	KIR2DL4	CD99	TRAV19	PVRL2	SELL	TREM1	CD19	ITGA4	AMICA1	CRTAM	C3	ITGB1	TYROBP	KLRK1	CD200R1	ITGB2	CD300LB	ICAM2	ICAM3	CD8B	KIR2DS2	CD300LD	CD300LF	NCR2	CD300E	CD300LG	
REGULATION OF TP53 ACTIVITY THROUGH METHYLATION%REACTOME%R-HSA-6804760.1	Regulation of TP53 Activity through Methylation	SETD8	RPS27A	EHMT1	CHEK2	JMY	TTC5	MDM2	MDM4	UBA52	L3MBTL1	ATM	SETD9	EHMT2	UBB	SMYD2	EP300	UBC	PRMT5	TP53	
BETA OXIDATION OF DECANOYL-COA TO OCTANOYL-COA-COA%REACTOME DATABASE ID RELEASE 74%77346	Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA	MECR	HADHB	HADHA	ECHS1	HADH	ACADM	
RETINOID METABOLISM AND TRANSPORT%REACTOME DATABASE ID RELEASE 74%975634	Retinoid metabolism and transport	APOE	RBP1	APOB	AGRN	LDLR	RBP2	GPC1	LRAT	GPIHBP1	LRP1	RETSAT	LRP2	LRP8	APOC3	APOM	BCO2	BCO1	APOC2	AKR1C1	AKR1C4	AKR1B10	LRP10	LRP12	SDC2	APOA2	SDC4	APOA1	APOA4	SDC3	GPC3	SDC1	GPC2	GPC5	GPC4	HSPG2	GPC6	AKR1C3	CLPS	RBP4	PLB1	TTR	LPL	PNLIP	RDH11	
MYOCLONIC EPILEPSY OF LAFORA%REACTOME%R-HSA-3785653.3	Myoclonic epilepsy of Lafora	RPS27A	EPM2A	GYS1	UBB	PPP1R3C	NHLRC1	GYG1	UBC	UBA52	
PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS%REACTOME%R-HSA-8850843.3	Phosphate bond hydrolysis by NTPDase proteins	ENTPD5	ENTPD2	ENTPD3	ENTPD4	ENTPD6	ENTPD7	ENTPD8	ENTPD1	
SIGNALING BY ERBB2%REACTOME DATABASE ID RELEASE 74%1227986	Signaling by ERBB2	PRKCE	SRC	PRKCA	MATK	USP8	RHOA	RNF41	UBA52	SHC1	PTPN18	EGF	GRB7	GAB1	ERBB2	EGFR	NRAS	CDC37	PLCG1	SOS1	HRAS	STUB1	UBB	PRKCD	PIK3R1	PTPN12	PIK3CA	UBC	AKT2	AKT3	HBEGF	RPS27A	AKT1	FYN	ERBB2IP	YES1	EREG	CUL5	BTC	PTK6	NRG1	NRG2	HSP90AA1	NRG3	NRG4	MEMO1	DIAPH1	
G2 M DNA REPLICATION CHECKPOINT%REACTOME DATABASE ID RELEASE 74%69478	G2 M DNA replication checkpoint	WEE1	CCNB2	CCNB1	PKMYT1	CDK1	
DEFECTIVE SLC24A5 CAUSES OCULOCUTANEOUS ALBINISM 6 (OCA6)%REACTOME%R-HSA-5619036.1	Defective SLC24A5 causes oculocutaneous albinism 6 (OCA6)	SLC24A5	
BINDING AND ENTRY OF HIV VIRION%REACTOME%R-HSA-173107.2	Binding and entry of HIV virion	CD4	PPIA	CCR5	CXCR4	
METABOLISM OF LIPIDS%REACTOME DATABASE ID RELEASE 74%556833	Metabolism of lipids	SEC23A	LRP2	SEC24B	ABCB4	SEC24A	RAB14	SEC24D	SEC24C	TBL1X	SCD5	ABCD1	ABCC3	ABCC1	PIK3CD	APOA1	PIK3CB	PIK3CG	CYP7B1	PIK3R5	PIP5K1A	PIP5K1B	TBL1XR1	PIP4K2A	PIP4K2B	PIP4K2C	NFYA	NFYB	NFYC	ECHS1	ACSM3	ACSM6	HADH	SBF2	ACADS	GSTM4	THRAP3	OCRL	FAM120B	FABP7	ACLY	OSBPL1A	CYP1B1	PTEN	GPX2	TMEM55B	SUMO2	PIAS4	TXNRD1	MAPKAPK2	PSAP	GLB1L	LPGAT1	CPNE7	PITPNB	CPNE6	LCLAT1	PLB1	LIPI	LIPH	CPNE1	CPNE3	MFSD2A	DGAT2	NUDT19	PCYT2	DGAT1	CSNK2A1	SLCO1B1	STARD7	HRASLS2	CSNK2A2	SLCO1B3	PISD	PLA2G15	PLA2G16	GNPAT	ACOT2	PHOSPHO1	GPD2	PLA2G10	GPD1	CSNK2B	PLBD1	HRASLS5	PLA2R1	SLCO1A2	PLA1A	PTGES3	CDS1	ABHD4	HAO2	ABHD3	CHAT	PLA2G3	PLD4	PLA2G5	ACBD5	PLD6	PLA2G6	PLD1	PRKACG	PLD3	PRKACB	PLD2	PON3	GPX1	PGS1	GPX4	PTDSS2	AMACR	PTDSS1	PON2	PTPMT1	ALOX5AP	OSBPL8	PON1	TMEM86B	LTC4S	GLA	CHKB	CROT	OSBPL5	CHKA	RARRES3	STARD10	EPT1	DGAT2L6	CRLS1	PEMT	ALPI	PIK3R4	CDS2	SLC44A5	ACHE	BAAT	SLC44A3	SLC44A4	ACOX2	SLC44A1	SLC44A2	LPCAT1	AGPS	PCTP	ACOX3	TAZ	OSBPL10	EP300	ACP6	FAM73A	FAM73B	PLA2G12A	RGL1	PLA2G4F	PCYT1B	PCYT1A	PLA2G4D	PLA2G4B	PLA2G4C	PLA2G4A	GPCPD1	HADHB	HADHA	PITPNM1	PITPNM3	PITPNM2	MGLL	NUDT7	AGPAT5	VAPA	AGPAT6	AGPAT9	PLA2G1B	CRAT	AGPAT1	AGPAT2	AGPAT3	AGPAT4	AWAT2	GPAT2	CEPT1	CDIPT	PLA2G2F	BCHE	BMX	PLA2G2D	PLA2G2E	PNPLA8	AGK	MBOAT7	PLA2G2A	DDHD2	MBOAT1	MBOAT2	DDHD1	ETNPPL	GPAM	LPCAT4	ETNK2	LPCAT3	ETNK1	EBP	SC5D	LPCAT2	DHCR24	PNPLA3	DHCR7	CHPT1	GPD1L	LPIN1	LPIN2	PPP1CC	LPIN3	PNPLA2	ELOVL1	FADS2	SCP2	ELOVL5	ELOVL2	ELOVL3	PIK3R6	HSD3B7	AKR1D1	AKR1C2	MTMR4	AKR1C1	AKR1C4	PPP1CA	FADS1	SULT2A1	CPT1A	ACSL1	CLOCK	FAAH	PEX11A	ACACA	CYP4A22	HPGDS	NRF1	NPAS2	PTGDS	FDFT1	CBR1	ALAS1	PTGIS	FHL2	FAAH2	PCCA	PTGR1	PCCB	GLIPR1	PTGR2	CPT2	ME1	PTGES	ANKRD1	ALOX12B	CYP4F22	ACADM	PTGS1	HMGCS1	FAM213B	CYP4A11	FDX1	MTF1	AWAT1	FDXR	PLIN2	ALOXE3	FDX1L	TNFRSF21	PTGES2	CYP7A1	EPHX2	CYP4F2	ARNTL	CYP4F3	UGT1A9	NR1H4	AKR1C3	G0S2	CYP4B1	CYP4F11	GRHL1	CYP4F8	AGT	FABP1	CYP8B1	PIK3C3	ALOX15B	ALOX15	ALOX12	SLC22A5	MID1IP1	THRSP	SLC25A20	BZRAP1	CPT1B	KPNB1	RAN	INPPL1	ACACB	PTPN13	FASN	INPP5E	CYP24A1	LGMN	ASAH1	PPARGC1B	TIAM2	CD36	HPGD	ALOX5	LTA4H	FABP9	ABHD5	FABP12	LIPE	FABP2	PIP5K1C	FABP3	PPARGC1A	FABP5	FABP6	PNPLA4	PNPLA5	SPHK1	SMPD3	STARD3	MED19	SMPD2	STARD4	MED16	STARD3NL	STARD6	MED15	MED18	STAR	MED17	CYP11A1	MED12	TSPO	MED11	AKR1B1	MED14	GM2A	MED13	GBA	MED10	PPARD	ARF3	MED27	MED26	ARF1	MED29	MED28	MED23	MED22	MED25	MED24	ACADL	MED21	ECI1	MED20	DECR1	PPARG	PPARA	SCD	FABP4	RORA	SACM1L	SBF1	PLIN3	MED30	MED31	ABCB11	MCEE	ACADVL	CCNC	SP1	NDUFAB1	MED13L	NCOA1	SLC27A1	UBE2I	NCOA2	NCOA6	NCOA3	SREBF2	RXRA	RXRB	MECR	PIK3R3	PIK3R2	PIK3R1	PIK3CA	MMAA	MUT	GPS2	THEM4	TRIB3	MVD	VDR	CAV1	NEU2	NEU3	NEU1	HMGCL	ACSS3	BDH2	AHR	BDH1	CYP2C19	CYP3A4	OXCT1	OXCT2	HMGCS2	HMGCLL1	CHD9	AACS	CTSA	CREBBP	ACAT1	CYP2D6	CYP2J2	ARNT2	SRD5A3	ARNT	CYP2C9	GLB1	CYP2C8	IDI1	FDPS	CYP1A2	CYP17A1	MVK	CYP1A1	GGPS1	AHRR	IDI2	CYP2E1	MSMO1	TGS1	PPAPDC2	NR1D1	HSD17B7	LSS	ACAT2	TM7SF2	SQLE	ARV1	NSDHL	PMVK	RAB5A	FIG4	VAC14	CARM1	MTMR2	PIKFYVE	MTMR9	PIK3C2A	MTM1	MTMR7	HEXB	HEXA	MED1	SIN3A	MED8	MED9	MED4	ARSB	MED6	MED7	SAMD8	PPM1L	ACOT9	PPAP2C	STARD5	SGMS2	ACOT7	ALDH3B2	CH25H	SGPL1	ACOT1	SPTLC1	FAR1	SPTLC2	FAR2	SPTLC3	HACD1	ALDH3B1	HACD3	ORMDL2	HSD17B1	HACD2	ORMDL3	HACD4	OSBP	HSD11B1	SPTSSB	UGT8	PTGS2	SPTSSA	HSD11B2	CDK19	KDSR	AGMO	CERS3	B3GALNT1	CERS4	MCAT	TBXAS1	CERS5	PPT1	CERS6	PPT2	SPHK2	SERPINA6	PRKAA2	SPNS2	SMPD4	ORMDL1	SMPD1	SGPP2	ELOVL4	SGPP1	PRKAG2	ELOVL6	ACER2	ELOVL7	ACER1	FA2H	ACSBG1	PRKD3	ACSBG2	ASAH2	VAPB	STS	GC	PPAP2B	PRKAB2	GK	ACER3	SLC27A3	PPAP2A	ARSJ	PRKD2	SLC27A5	INSIG2	ARSK	DEGS1	PRKD1	INSIG1	ARSH	TNFAIP8	MTMR14	THEM5	ARSI	DEGS2	CSNK1G2	OSBPL9	GDE1	NCOR2	OSBPL7	PIK3C2G	CERS1	ARSF	NCOR1	OSBPL6	PIK3C2B	CERS2	SRD5A2	ARSG	TNFAIP8L1	SRD5A1	TNFAIP8L3	OSBPL3	ARSD	TNFAIP8L2	OSBPL2	ARSE	ENPP6	PI4K2B	PLIN1	TECRL	TPTE2	RUFY1	MTMR10	SLC25A1	ARSA	MTMR1	MTMR12	HSD17B14	MTMR3	SUMF2	HSD17B13	INPP4A	MTMR8	SUMF1	HSD17B12	INPP4B	HSD17B11	INPP5F	GDPD1	PI4K2A	TPTE	GLTP	CERK	GDPD3	GBA2	GDPD5	MTMR6	ACAD11	ACAD10	INPP5J	ESRRA	ACSL6	INPP5K	ACSL5	PLEKHA1	UGCG	PNPLA7	SCAP	PLEKHA5	B4GALNT1	PLEKHA6	SLC10A1	PLEKHA3	SLC10A2	PLEKHA4	CIDEA	PLEKHA8	CIDEC	PI4KB	AKR1B15	PNPLA6	MOGAT3	MOGAT2	MOGAT1	TECR	HILPDA	HSD17B3	FITM1	FITM2	HSD17B8	HSD17B2	LBR	CBR4	OLAH	ESYT3	ESYT2	ESYT1	ACAA2	ENPP7	PECR	ACOT11	PHYH	ACOT12	SLC25A17	ACOT13	HACL1	DHRS7B	SLC27A2	MORC2	ACBD7	ACBD6	ACBD4	ACOT8	ACSF3	CDK8	ACSF2	EHHADH	HSD17B4	DBI	DECR2	CPTP	ACOT6	GK2	ACAA1	GALC	ACOT4	CYP46A1	CYP2U1	CYP39A1	CYP27A1	INPP5D	CYP19A1	LHB	CYP27B1	CGA	CUBN	CYP11B2	CYP11B1	ACOXL	APOA2	CYP2R1	CYP21A2	APOA5	ANGPTL4	SAR1B	SMARCD3	HDAC3	ABCA1	ACSL4	MBTPS1	NR1H2	ACSL3	GGT1	CYP51A1	NR1H3	DPEP2	DPEP1	DPEP3	ALB	MBTPS2	GGT5	RAB4A	PPP1CB	POMC	SYNJ2	PRKACA	SYNJ1	HELZ2	HSD3B2	HSD3B1	
TRANSPORT OF GLYCEROL FROM ADIPOCYTES TO THE LIVER BY AQUAPORINS%REACTOME%R-HSA-432030.1	Transport of glycerol from adipocytes to the liver by Aquaporins	AQP9	AQP7	
MICROBIAL MODULATION OF RIPK1-MEDIATED REGULATED NECROSIS%REACTOME%R-HSA-9686347.1	Microbial modulation of RIPK1-mediated regulated necrosis	RIPK3	CASP8	MLKL	RIPK1	
DEFECTIVE CSF2RB CAUSES SMDP5%REACTOME%R-HSA-5688849.2	Defective CSF2RB causes SMDP5	SFTPC	SFTPD	CSF2RB	CSF2RA	SFTPA2	SFTA3	SFTPA1	SFTPB	
DEFECTIVE SLC33A1 CAUSES SPASTIC PARAPLEGIA 42 (SPG42)%REACTOME%R-HSA-5619061.1	Defective SLC33A1 causes spastic paraplegia 42 (SPG42)	SLC33A1	
RUNX3 REGULATES YAP1-MEDIATED TRANSCRIPTION%REACTOME%R-HSA-8951671.1	RUNX3 regulates YAP1-mediated transcription	YAP1	RUNX3	TEAD1	TEAD2	WWTR1	TEAD3	TEAD4	CTGF	
ANTI-INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION%REACTOME%R-HSA-9662851.1	Anti-inflammatory response favouring Leishmania parasite infection	ADCY2	ADCY1	ADCY8	ADCY7	CREB1	ADCY6	ADCY5	GNG12	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	HCK	PRKAR2B	PLCG2	GLP1R	VIPR1	VIPR2	SCT	MYH9	ADM	PTH1R	CYSLTR2	SYK	IL10	IL6	GLP2R	CD163	PLK2	PTH2R	RHBDF2	GIP	ADCYAP1	CRH	IAPP	CALCA	RAMP2	ADCYAP1R1	RAMP3	CALCRL	CALCB	GIPR	PTH	PTH2	PTHLH	ADAM17	CRHR1	GHRHR	CALCR	IGKV2-28	SCTR	IGKV1-12	IGKV3D-20	GCG	IGKV2D-28	ADM2	GHRH	IGKV4-1	VIP	RAMP1	IGKV2D-30	IGKV3-11	PLCG1	LYN	IGKV5-2	RXFP1	ADRB1	RXFP2	GPR176	ADRB2	GNAT3	HTR4	PTGDR	HTR6	HTR7	LHB	HRH2	CRHR2	DRD1	MC2R	CGA	AHCYL1	GPR15	DRD5	MC1R	CD3G	TAAR8	PRKX	GPR27	FCGR3A	TAAR9	GPR25	FCGR1A	MAPK14	YES1	GPR20	TAAR6	MC4R	FGR	GPR39	FCGR2A	FSHB	GPR32	TAAR5	TAAR2	GPBAR1	MC3R	TAAR1	FSHR	NPSR1	ADRB3	PTGER4	GPR45	PTGER2	FURIN	GNAI3	GNAI1	GNAI2	NPS	GPR150	GPHA2	P2RY11	MC5R	GPHB5	CYSLTR1	GGT1	LHCGR	DPEP2	DPEP1	DPEP3	GNAZ	GPR83	GPR84	IGHG4	AVP	IGHG1	GGT5	IGHG2	RLN2	ADORA2A	RLN3	INSL3	TSHB	PRKACG	PTGIR	PRKACB	AVPR2	GNGT1	ADORA2B	TSHR	GNGT2	POMC	ADCY9	PRKAR1B	FYN	PRKAR1A	PRKACA	PRKAR2A	ITPR1	ITPR2	ITPR3	GNAS	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	ADCY4	ADCY3	
MET RECEPTOR RECYCLING%REACTOME DATABASE ID RELEASE 74%8875656	MET receptor recycling	GAB1	GGA3	CRKL	RAB4B	HGF	CRK	MET	RAB4A	ARF6	
RECYCLING PATHWAY OF L1%REACTOME DATABASE ID RELEASE 74%437239	Recycling pathway of L1	RPS6KA1	DNM1	RDX	DNM2	DNM3	AP2B1	RPS6KA4	L1CAM	SH3GL2	SHTN1	AP2A1	AP2A2	EZR	KIF4B	MAPK1	KIF4A	AP2M1	CLTC	CLTA	MSN	DPYSL2	NUMB	RPS6KA3	RPS6KA6	RPS6KA5	RPS6KA2	AP2S1	
EICOSANOID LIGAND-BINDING RECEPTORS%REACTOME DATABASE ID RELEASE 74%391903	Eicosanoid ligand-binding receptors	PTGER3	LTB4R	CYSLTR1	OXER1	GPR17	LTB4R2	PTGER4	PTGER2	CYSLTR2	PTGFR	TBXA2R	PTGIR	PTGDR2	PTGDR	PTGER1	
SIGNALING BY ROBO RECEPTORS%REACTOME%R-HSA-376176.5	Signaling by ROBO receptors	ROBO1	ISL1	UBA52	UBB	UBC	CXCR4	AKAP5	RPS27A	CLASP1	UPF2	ARHGAP39	ZSWIM8	MSI1	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	USP33	RPL7	RPS15	RPS14	RPS17	DCC	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	CXCL12	RPL39	RPS10	RPS13	CLASP2	RPS12	RPS9	RPL21	NCK2	RPS7	RPS8	RPL23	RPS5	RPL22	PSMD8	RPS6	RPSA	PSMD9	RPL24	ETF1	PSMD6	RPL27	PSMD7	RPL26	PSMD4	RPL29	PSMD5	RPL28	PSMD2	RPS4Y2	PSMD3	RPS4Y1	PSMD1	NTN1	RPL39L	PSMA5	RPL41	PSMA6	PSMA3	NELL2	RPL3L	PSMA4	RPS26	PSMA1	RPS25	PSMA2	PSME3	RPS28	PSME4	PSME1	RPS27	PSME2	RPS29	RPL27A	RPS20	PSMD10	RPS21	PSMB11	RPS24	PSMD12	RPS23	PSMD11	RPLP1	PSMD14	RPLP0	PSMD13	RPS4X	RPL7A	PSMB10	RPLP2	PSMA7	PSMA8	RPL13A	PSMB6	RPS3A	PSMB7	RPL37A	RPL10	PSMB4	RPL12	PSMB5	RPL11	PSMB2	PSMB3	RPL36A	PABPC1	RPS27L	PSMB1	PSMF1	RPS15A	RPL14	SHFM1	RPS3	PSMB8	GSPT2	RPL13	PSMB9	RPL15	GSPT1	RPS2	PSMC5	RPL18	PSMC6	RPL17	PSMC3	PSMC4	PSMC1	RPL19	PSMC2	RPL35A	RPL23A	EIF4G1	NRP1	RPL22L1	CAP1	FAU	NCK1	RPL26L1	ENAH	GPC1	PAK7	SRC	PAK6	PAK4	CAP2	MYO9B	PRKACG	PRKACB	PPP3CB	RBX1	PRKAR2A	LDB1	PAK1	PAK3	PAK2	ABL1	SLIT1	SLIT3	SLIT2	TCEB2	TCEB1	HOXA2	RAC1	CDC42	FLRT3	UPF3A	RHOA	COL4A5	EIF4A3	CASC3	MAGOH	NCBP1	NCBP2	RBM8A	UPF3B	MAGOHB	RNPS1	CUL2	ABL2	SRGAP3	SRGAP1	LHX3	LHX2	SOS1	LHX4	LHX9	EVL	SOS2	PRKCA	DAG1	PFN1	PFN2	PRKACA	VASP	ROBO2	
NECTIN NECL TRANS HETERODIMERIZATION%REACTOME%R-HSA-420597.2	Nectin Necl trans heterodimerization	PVRL4	PVRL3	PVRL2	PVRL1	PVR	CADM3	CADM1	
STRIATED MUSCLE CONTRACTION%REACTOME%R-HSA-390522.1	Striated Muscle Contraction	MYL4	DES	MYH3	MYL1	TNNT1	MYL2	TNNT2	MYL3	TNNT3	MYH8	TCAP	MYH6	TTN	TPM4	TPM3	TPM2	TPM1	ACTN2	TNNI1	TNNI2	TNNI3	DMD	MYBPC3	VIM	TMOD1	MYBPC1	MYBPC2	ACTN3	TMOD4	TNNC1	TMOD3	TNNC2	TMOD2	NEB	
GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT%REACTOME DATABASE ID RELEASE 74%72706	GTP hydrolysis and joining of the 60S ribosomal subunit	UBA52	EIF2S2	EIF2S1	EIF2S3	RPS27A	RPL4	EIF4A2	EIF4A1	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	EIF1AX	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	EIF5	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	EIF5B	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	EIF4H	RPL13	RPL15	RPS2	RPL18	RPL17	EIF4E	EIF4B	RPL19	RPL35A	RPL23A	EIF3M	EIF3K	EIF3L	EIF3I	EIF4G1	EIF3J	EIF3G	EIF3H	EIF3E	RPL22L1	EIF3F	FAU	EIF3C	EIF3D	EIF3A	RPL26L1	EIF3B	
DEFECTIVE GIF CAUSES INTRINSIC FACTOR DEFICIENCY%REACTOME%R-HSA-3359457.1	Defective GIF causes intrinsic factor deficiency	GIF	
MYD88:MAL(TIRAP) CASCADE INITIATED ON PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 74%166058	MyD88:MAL(TIRAP) cascade initiated on plasma membrane	RPS6KA1	RIPK2	MAPK3	IRAK3	IRAK4	FOS	CREB1	TIRAP	DUSP4	TLR1	TRAF6	PELI1	UBA52	UBE2V1	TLR6	DUSP6	DUSP7	CUL1	RELA	TLR2	UBE2N	PELI3	UBB	TAB3	PELI2	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	MAP3K1	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	BTK	LY96	CD14	TLR4	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	SIGIRR	PPP2R1A	MAPKAPK3	AGER	BTRC	SOCS1	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	MYD88	ECSIT	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	CD36	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
INACTIVATION OF CDC42 AND RAC1%REACTOME%R-HSA-428543.2	Inactivation of CDC42 and RAC1	ARHGAP39	ROBO1	CDC42	SRGAP3	RAC1	SRGAP1	SLIT2	
HDL ASSEMBLY%REACTOME DATABASE ID RELEASE 74%8963896	HDL assembly	ABCA1	A2M	PRKACA	APOA1	ZDHHC8	PRKACG	PRKACB	
BIOSYNTHESIS OF DPAN-3-DERIVED 13-SERIES RESOLVINS%REACTOME DATABASE ID RELEASE 74%9026403	Biosynthesis of DPAn-3-derived 13-series resolvins	ALOX5	
SIGNALING BY FGFR2 IN DISEASE%REACTOME%R-HSA-5655253.1	Signaling by FGFR2 in disease	FGF20	FGF23	FGF22	GAB1	FGF16	NRAS	PLCG1	SOS1	HRAS	FGF18	PIK3R1	POLR2A	PIK3CA	POLR2B	POLR2C	FGF10	POLR2D	NCBP1	NCBP2	POLR2E	POLR2F	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	FRS2	FGF1	FGF2	FGF3	FGF4	FGFR2	FGF6	FGF7	FGF9	
NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION%REACTOME%R-HSA-9013695.1	NOTCH4 Intracellular Domain Regulates Transcription	NOTCH4	FLT4	MAML3	MAMLD1	SNW1	NOTCH2	NOTCH1	MAML2	SMAD3	MAML1	KAT2B	HEY1	RBPJ	KAT2A	HEY2	CREBBP	ACTA2	EP300	HES1	HES5	
TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS%REACTOME%R-HSA-452723.2	Transcriptional regulation of pluripotent stem cells	PRDM14	ZSCAN10	KLF4	POU5F1	SMAD4	FGF2	STAT3	SMAD2	HIF3A	LIN28A	SOX2	SALL1	PBX1	SALL4	NANOG	FOXD3	EPHA1	ZIC3	TDGF1	EPAS1	NR5A1	DPPA4	
NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY%REACTOME%R-HSA-168333.3	NEP NS2 Interacts with the Cellular Export Machinery	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	XPO1	NUP205	NUP54	POM121	AAAS	NUP160	NUP85	TPR	NUP88	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	RAN	NUP107	NUP153	NUP188	
DCC MEDIATED ATTRACTIVE SIGNALING%REACTOME%R-HSA-418885.1	DCC mediated attractive signaling	ABLIM1	ABLIM2	ABLIM3	SRC	RAC1	WASL	DOCK1	NCK1	CDC42	PTK2	DCC	NTN1	TRIO	
DOWNSTREAM TCR SIGNALING%REACTOME%R-HSA-202424.4	Downstream TCR signaling	RIPK2	UBE2D1	UBA52	CUL1	UBB	UBC	RPS27A	PIK3CB	TRAT1	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	UBE2D2	PSME3	PSME4	PSME1	PSME2	CDC34	CARD11	PTEN	PSMD10	TRAF6	PSMB11	PSMD12	PSMD11	PRKCQ	PSMD14	UBE2V1	PSMD13	BCL10	PSMB10	MALT1	PSMA7	RELA	PSMA8	PSMB6	UBE2N	PSMB7	PSMB4	TAB2	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	INPP5D	SHFM1	PSMB8	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CD3G	CD3E	CD3D	HLA-DPA1	HLA-DQB2	HLA-DQB1	HLA-DQA2	HLA-DQA1	TRAV19	HLA-DRB5	HLA-DRB4	CD4	HLA-DPB1	HLA-DRA	HLA-DRB3	HLA-DRB1	PDPK1	PIK3R2	PIK3R1	PIK3CA	LCK	BTRC	SKP1	FBXW11	
SEPARATION OF SISTER CHROMATIDS%REACTOME DATABASE ID RELEASE 74%2467813	Separation of Sister Chromatids	RCC2	DYNC1LI1	NDC80	DYNLL1	ZWINT	DYNC1LI2	STAG1	CKAP5	STAG2	AHCTF1	ZW10	SGOL2	UBE2D1	SGOL1	CDC23	NUF2	CDC26	WAPAL	MAPRE1	CDC27	SPDL1	SEC13	NDEL1	NUP133	ANAPC7	UBA52	NUDC	UBE2E1	RANGAP1	SMC1A	PAFAH1B1	INCENP	BIRC5	DYNC1I2	ITGB3BP	MIS12	CENPA	ANAPC4	AURKB	NSL1	ANAPC5	CENPC	BUB1	ANAPC1	UBB	CENPT	CENPU	ANAPC2	CENPF	ANAPC15	APITD1	ANAPC16	UBC	CENPH	ANAPC10	CENPI	ANAPC11	TAOK1	CENPK	RPS27A	CENPL	CENPM	KIF18A	PPP2CA	CENPN	CLASP1	CENPO	PPP2CB	B9D2	CENPP	DYNC1H1	CENPQ	UBE2C	NUP43	SPC24	SPC25	UBE2S	RANBP2	NDE1	PLK1	CDC16	CLIP1	NUP37	PPP1CC	PTTG1	DYNLL2	KIF2A	KIF2C	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	CLASP2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	DYNC1I1	PSMD2	PSMD3	PSMD1	PSMA5	CENPE	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	RPS27	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	XPO1	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	NUP107	PPP2R1B	ESPL1	NUP160	NUP85	PPP2R1A	ERCC6L	ZWILCH	CASC5	SMC3	KNTC1	MAD1L1	CDCA5	CDCA8	PDS5B	PDS5A	PMF1	SKA1	SKA2	DSN1	RAD21	
REGULATION OF PTEN GENE TRANSCRIPTION%REACTOME%R-HSA-8943724.1	Regulation of PTEN gene transcription	MAPK3	PHC2	PHC1	HDAC5	PHC3	HDAC7	EZH2	RING1	SUZ12	MAPK1	PPARG	HDAC2	HDAC1	CBX8	HDAC3	CBX6	CBX4	CBX2	SNAI1	SNAI2	MECOM	ATN1	MAF1	NR2E1	BMI1	RPTOR	SLC38A9	CHD4	CHD3	MTOR	ATF2	REST	RRAGA	RRAGC	MTA1	MLST8	RBBP4	RRAGB	RHEB	RRAGD	LAMTOR2	RBBP7	LAMTOR1	MTA2	LAMTOR4	MTA3	LAMTOR3	MBD3	LAMTOR5	RNF2	GATAD2B	GATAD2A	JUN	KDM1A	EGR1	SALL4	EED	TP53	
CYP2E1 REACTIONS%REACTOME DATABASE ID RELEASE 74%211999	CYP2E1 reactions	CYP2C9	CYP2A7	CYP2A6	CYP2C19	CYP2C8	CYP2S1	CYP2B6	CYP2A13	CYP2D6	CYP2E1	CYP2F1	
PRC2 METHYLATES HISTONES AND DNA%REACTOME DATABASE ID RELEASE 74%212300	PRC2 methylates histones and DNA	HIST2H2AC	DNMT3A	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	DNMT1	HIST4H4	DNMT3B	EZH2	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	SUZ12	HIST2H4A	HIST2H4B	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	RBBP4	HIST1H3F	HIST1H3G	PHF19	PHF1	HIST1H3H	JARID2	RBBP7	HIST1H3I	HIST1H3B	HIST1H3C	AEBP2	HIST1H3D	HIST1H3E	MTF2	H3F3B	HIST1H4K	HIST1H4L	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	EED	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
LXR-MEDIATED SIGNALING%REACTOME%R-HSA-9024446.2	LXR-mediated signaling	RXRA	APOE	ABCG8	ABCA1	ABCG5	TBL1XR1	NR1H2	APOC4	TNRC6C	ABCG1	MOV10	NR1H3	AGO3	AGO4	APOC2	AGO1	FABP6	AGO2	APOC1	RXRB	NRIP1	TNRC6A	TNRC6B	NCOR2	FASN	GPS2	NCOR1	TBL1X	PLIN1	KDM3A	PCK1	KDM1B	KDM4A	MYLIP	ARL4C	EEPD1	ANGPTL3	KDM1A	NCOA1	SCD	CETP	UGT1A3	EP300	APOD	HDAC3	
REGULATION OF IFNA SIGNALING%REACTOME%R-HSA-912694.1	Regulation of IFNA signaling	IFNA6	IFNA1	IFNA10	USP18	IFNA2	PTPN11	JAK1	IFNA8	TYK2	SOCS1	IFNA21	SOCS3	IFNAR1	PTPN6	IFNA13	IFNA5	PTPN1	IFNA14	IFNA16	STAT2	IFNA4	IFNA17	IFNA7	IFNB1	
OAS ANTIVIRAL RESPONSE%REACTOME%R-HSA-8983711.2	OAS antiviral response	OASL	RNASEL	DDX58	FLNA	OAS1	PDE12	OAS2	OAS3	ABCE1	
AROMATIC AMINES CAN BE N-HYDROXYLATED OR N-DEALKYLATED BY CYP1A2%REACTOME DATABASE ID RELEASE 74%211957	Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2	CYP1A2	
PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS%REACTOME%R-HSA-622323.2	Presynaptic nicotinic acetylcholine receptors	CHRNA5	CHRNA4	CHRNA6	CHRND	CHRNG	CHRNE	CHRNA1	CHRNB2	CHRNA3	CHRNB4	CHRNB3	CHRNA2	
CARGO RECOGNITION FOR CLATHRIN-MEDIATED ENDOCYTOSIS%REACTOME DATABASE ID RELEASE 74%8856825	Cargo recognition for clathrin-mediated endocytosis	SH3KBP1	SGIP1	AREG	FZD4	STAM	HGS	NEDD8	LRP2	CFTR	FCHO1	FCHO2	UBA52	UBQLN1	UBQLN2	STAM2	TGOLN2	NECAP2	NECAP1	ADRBK1	SYT11	UBB	TF	UBC	HBEGF	M6PR	RPS27A	AGFG1	IGF2R	EPGN	SNAP91	CLTB	SCARB2	VAMP4	CLTCL1	VAMP3	ARRB1	ARRB2	SYT2	SYT1	SYT9	SYT8	IL7R	PICALM	SLC2A8	EPN1	EPN2	ITSN2	REPS2	EPS15	REPS1	SH3GL1	EGF	CHRM2	AGTR1	CBL	COPS7B	EGFR	COPS7A	ADRB2	AP2A1	AP2A2	LDLRAP1	AP2M1	CD3G	CLTC	CLTA	STON1	STON2	SLC18A3	CD3D	EPS15L1	TACR1	VAMP8	VAMP7	VAMP2	GPS1	AP2S1	APOB	LDLR	ADRBK2	CD4	AP2B1	DVL2	SH3GL2	AVP	KIAA0319	TOR1A	AVPR2	WNT5A	TOR1B	TFRC	COPS4	COPS3	EREG	COPS6	SH3GL3	BTC	DAB2	COPS5	TGFA	COPS2	AAK1	COPS8	ITSN1	
METABOLISM OF FAT-SOLUBLE VITAMINS%REACTOME%R-HSA-6806667.5	Metabolism of fat-soluble vitamins	APOE	RBP1	APOB	AGRN	TTPA	LDLR	RBP2	GPC1	LRAT	GPIHBP1	LRP1	UBIAD1	RETSAT	LRP2	LRP8	APOC3	APOM	BCO2	BCO1	APOC2	AKR1C1	AKR1C4	AKR1B10	LRP10	LRP12	SDC2	APOA2	SDC4	VKORC1	APOA1	APOA4	SDC3	GPC3	SDC1	GPC2	GPC5	GPC4	HSPG2	GPC6	AKR1C3	VKORC1L1	CLPS	RBP4	PLB1	TTR	LPL	PNLIP	RDH11	
PRPP BIOSYNTHESIS%REACTOME%R-HSA-73843.2	PRPP biosynthesis	PRPS2	PRPS1	
VIRAL MRNA TRANSLATION%REACTOME%R-HSA-192823.4	Viral mRNA Translation	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	UBA52	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	RPS27A	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	GRSF1	DNAJC3	RPL22L1	FAU	RPL26L1	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	
CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT%REACTOME DATABASE ID RELEASE 74%9603798	Class I peroxisomal membrane protein import	ABCD2	PXMP2	ABCD3	PXMP4	PEX12	PEX16	PEX13	ATAD1	PEX14	ABCD1	SLC25A17	GDAP1	PEX11B	PEX3	PEX2	PEX19	FIS1	ACBD5	PEX26	
TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX%REACTOME DATABASE ID RELEASE 74%1362277	Transcription of E2F targets under negative control by DREAM complex	MYC	CDC6	CDC25A	PCNA	TOP2A	LIN54	LIN37	RBL2	MAX	RBL1	LIN9	E2F4	E2F5	TFDP1	LIN52	HDAC1	TFDP2	E2F1	RBBP4	
DEFECTIVE POMGNT1 CAUSES MDDGA3, MDDGB3 AND MDDGC3%REACTOME%R-HSA-5083628.1	Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3	DAG1	POMGNT1	
GLYCOGEN SYNTHESIS%REACTOME%R-HSA-3322077.4	Glycogen synthesis	RPS27A	GYS2	EPM2A	PGM1	UBA52	UGP2	GYS1	PGM2L1	UBB	PPP1R3C	PGM2	NHLRC1	GYG2	GYG1	UBC	GBE1	
RUNX1 INTERACTS WITH CO-FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN%REACTOME%R-HSA-8939243.1	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	PHC2	CSNK2A1	CBFB	PHC1	CSNK2A2	ARID1A	ARID1B	SMARCA2	SMARCD1	PHC3	SMARCD2	BMI1	CSNK2B	PBRM1	YAF2	SMARCE1	ACTL6B	ARID2	RING1	ACTL6A	RUNX1	AUTS2	HIPK2	SMARCA4	SMARCB1	RNF2	PCGF5	RYBP	SMARCC1	SMARCC2	CBX8	SMARCD3	EP300	CBX6	CBX4	CBX2	
SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA-HYDROXYCHOLESTEROL%REACTOME%R-HSA-193368.1	Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	ABCB11	AMACR	RXRA	PTGIS	SLC27A2	ACOT8	AKR1C1	CYP7B1	HSD17B4	AKR1C4	BAAT	CYP7A1	NCOA1	ACOX2	NCOA2	NR1H4	AKR1C3	SLC27A5	CYP8B1	CYP27A1	HSD3B7	AKR1D1	AKR1C2	
TELOMERE MAINTENANCE%REACTOME DATABASE ID RELEASE 74%157579	Telomere Maintenance	HIST2H2AC	H2AFJ	NOP10	H2AFZ	H2AFX	H2AFV	CCNA2	CCNA1	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	RTEL1	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	BLM	RPA1	RPA2	CDK2	HIST3H3	WRAP53	RPA3	PRIM2	DSCC1	PRIM1	CHTF18	WRN	CHTF8	OBFC1	CTC1	POLA1	POLA2	TEN1	DNA2	DAXX	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	RFC5	POLR2I	RFC3	POLR2J	FEN1	PCNA	POLR2K	RFC4	POLR2L	RFC1	LIG1	RFC2	POLD3	POLD4	POLD1	POLD2	RUVBL1	RUVBL2	SHQ1	PIF1	TERT	ATRX	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	TINF2	TERF1	TERF2	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	GAR1	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	ANKRD28	H3F3B	HIST1H4K	HIST1H4L	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	DKC1	HIST1H4D	HIST1H4E	PPP6C	NHP2	HIST1H4F	HIST2H2AA3	HIST2H2AA4	PPP6R3	
RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING%REACTOME DATABASE ID RELEASE 74%8939256	RUNX1 regulates transcription of genes involved in WNT signaling	CBFB	RSPO3	ESR1	AXIN1	FOXP3	RUNX1	
GSD IV%REACTOME%R-HSA-3878781.2	GSD IV	GYS2	GYG2	GBE1	
CARBOHYDRATE METABOLISM%REACTOME%R-HSA-71387.9	Carbohydrate metabolism	CHST7	CHPF2	CHST1	B4GALT7	CHST5	B4GALT4	CHST2	NUP62	CHST3	CHSY1	NDC1	HAS1	SEC13	HAS3	SLC26A2	HAS2	SLC26A1	NUP133	UBA52	CHSY3	PYGB	B3GAT2	AGL	B3GAT1	GAA	HS3ST5	PHKB	HS3ST6	PHKA1	LYVE1	PYGM	SLC9A1	HS3ST4	PYGL	NUP50	HS3ST1	PHKA2	HS3ST2	PGM2L1	NUP54	PHKG1	PHKG2	UBB	PGM2	GYG2	GYG1	UBC	AKR1B1	RPS27A	PPP2CA	PPP2CB	NUP43	RAE1	RANBP2	ABCC5	SLC25A10	NUP35	NUPL2	NUP37	MANBA	GYS1	B4GALT1	STAB2	AGRN	GOT1	GOT2	TALDO1	TKT	MAN2B1	RHCE	RHD	AKR1A1	GALT	GALE	PGM1	GALK1	G6PD	TKFC	ST3GAL4	ST3GAL1	ST3GAL2	ST3GAL3	SDC2	CHST6	PCK1	GLB1L	LUM	OGN	OMD	PRELP	KERA	FMOD	GNS	SLC35B3	SLC35B2	SLC35D2	GPC1	G6PC	PRKACG	PRKACB	FUT3	ST6GALNAC6	UGP2	ST3GAL6	SLC25A12	B3GNT7	SLC25A13	B3GNT4	ALDH1A1	GYS2	B3GNT3	B3GNT2	GLB1	B4GALT6	B4GALT5	MDH2	IDUA	HEXB	NCAN	HEXA	BGN	VCAN	HYAL1	PRPS2	HYAL3	PRPS1	IDS	RPEL1	SDC4	CSPG5	RPE	PGD	CSPG4	B3GAT3	SDC3	ARSB	DERA	GPC3	RPIA	SDC1	GPI	SHPK	GPC2	ADPGK	PGLS	ENO1	GPC5	RBKS	ENO2	GPC4	ENO3	GPC6	HK2	HK1	HK3	TPI1	PGAM1	PGAM2	BPGM	GAPDHS	PGP	ALDOC	ALDOB	ALDOA	GAPDH	PFKFB2	PFKFB1	PFKFB4	PFKFB3	PGK1	PGK2	PFKL	GNPDA1	GNPDA2	PFKM	PFKP	PAPSS1	PPP1R3C	NHLRC1	GBE1	EPM2A	SLC25A1	G6PC3	DCXR	GCKR	GCK	PC	PPP2R5D	HSPG2	BCAN	B4GALNT2	MAN2B2	MAN2C1	FUT2	FUT1	SLC2A1	DCN	NUP107	NUP188	CD44	PPP2R1B	NUP214	NUP210	NUP93	KHK	NUP205	POM121	CHPF	HPSE2	AAAS	XYLT2	XYLT1	NUP160	HS6ST1	HS6ST2	NUP85	HS6ST3	TPR	NDST2	NDST1	NUP88	NAGLU	NDST4	NDST3	XYLB	FUT10	CHP1	PPP2R1A	FUT11	CSGALNACT1	GLCE	PCK2	B3GALT2	CSGALNACT2	B3GALT1	CEMIP	PRKACA	HS3ST3A1	B4GAT1	MDH1	NUP155	GLYCTK	HMMR	CHST11	FUT4	CHST12	FUT6	FUT5	DSEL	CHST15	FUT7	CHST13	FUT9	CHST14	SLC37A1	B3GALT4	B3GALT6	NUP153	EXT1	B3GALT5	EXT2	G6PC2	UST	CRYL1	HPSE	SORD	B4GALT2	LALBA	PAPSS2	B4GALT3	SLC25A11	SGSH	FBP1	HS2ST1	FBP2	HYAL2	DSE	GUSB	HS3ST3B1	
TELOMERE C-STRAND SYNTHESIS INITIATION%REACTOME%R-HSA-174430.4	Telomere C-strand synthesis initiation	POLA2	TEN1	TINF2	TERF1	TERF2	POT1	TERF2IP	ACD	PRIM2	PRIM1	OBFC1	CTC1	POLA1	
DEFECTIVE BINDING OF RB1 MUTANTS TO E2F1,(E2F2, E2F3)%REACTOME DATABASE ID RELEASE 74%9661069	Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	CDKN1A	CCND2	CDKN1B	E2F3	CDK6	CDK2	CCND1	CDK4	CCND3	CCNE2	CCNE1	RB1	CDKN1C	TFDP1	TFDP2	E2F2	E2F1	
SEALING OF THE NUCLEAR ENVELOPE (NE) BY ESCRT-III%REACTOME DATABASE ID RELEASE 74%9668328	Sealing of the nuclear envelope (NE) by ESCRT-III	TUBB8	TUBA3E	TUBA1C	TUBA4A	TUBB6	TUBA1B	TUBB3	LEMD2	CHMP2B	TUBB1	CHMP2A	CHMP4C	CHMP4B	CHMP3	CHMP4A	CHMP6	CHMP7	TUBB2B	TUBB2A	TUBA4B	TUBAL3	TUBA1A	TUBB4B	TUBA8	TUBB4A	IST1	SPAST	CC2D1B	VPS4A	TUBB8P12	
SUMOYLATION OF UBIQUITINYLATION PROTEINS%REACTOME%R-HSA-3232142.3	SUMOylation of ubiquitinylation proteins	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	MDM2	NUP133	PIAS1	NUP50	NUP205	NUP54	POM121	PIAS4	AAAS	NUP160	NUP85	TPR	PML	NUP88	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	TRIM27	NUP107	SUMO1	NUP153	NUP188	UBE2I	VHL	
CLASS A 1 (RHODOPSIN-LIKE RECEPTORS)%REACTOME%R-HSA-373076.7	Class A 1 (Rhodopsin-like receptors)	RRH	EDNRA	EDNRB	UTS2R	GPR37L1	UTS2B	CXCR4	SSTR3	SAA1	MCHR1	NLN	PPY	PDYN	NTSR1	CCR10	NTSR2	NMB	XCR1	NMBR	NMS	NMU	CX3CL1	BRS3	CCKAR	GRP	FFAR3	CXCL8	FFAR2	CCL2	FFAR4	FFAR1	EDN1	EDN2	EDN3	CCKBR	NPB	CXCR5	CYSLTR2	CXCR6	CXCR1	NPW	CXCR3	CXCR2	KISS1R	CXCL12	F2RL1	RHO	PMCH	NPY2R	GHSR	NPY1R	APLNR	SUCNR1	AGTR2	NTS	NPBWR1	NPBWR2	OPN4	OPN3	OPN5	PYY	GPR18	NMUR2	NMUR1	GPR37	CXCL6	GPR35	GPR31	CXCL9	NPFFR2	MLNR	SST	NPFFR1	NPFF	QRFPR	HCRT	PSAP	CXCL3	QRFP	CXCL5	HCRTR2	CCR5	PROKR1	HCRTR1	PROKR2	BDKRB2	BDKRB1	PPBP	GPR55	NPY5R	GPR68	GPR65	CXCL13	CXCL16	CORT	C5AR2	C5AR1	C5	NPY4R	P2RY12	UTS2	OPRL1	CXCL11	ECE1	F2RL2	F2RL3	PRLHR	S1PR3	AVP	S1PR2	S1PR5	ADORA2A	S1PR4	KISS1	CCL7	CCL1	APLN	OXER1	KEL	OXTR	AVPR1B	OXT	AVPR1A	LPAR1	LPAR2	LPAR3	PENK	LPAR5	GNRH2	GNRH1	MLN	GNRHR	CCR9	CCR8	CCR7	CCR6	CCR4	CCR3	OXGR1	GAL	PRLH	XK	PTGFR	TBXA2R	PTGDR2	CCRL2	PTGER1	PTGER3	PTAFR	MCHR2	HCAR2	HCAR3	HCAR1	TAC3	TAC1	LTB4R	HEBP1	ANXA1	FPR1	FPR3	FPR2	GPER1	CCL11	SSTR1	SSTR2	SSTR4	CCL19	SSTR5	CCL22	AGT	CCL20	CNR2	CNR1	CXCL10	CCK	CCL5	CCL4	AGTR1	CHRM2	CCL3	CHRM3	ACKR4	CHRM1	ACKR3	CHRM4	ACKR2	CHRM5	ACKR1	HTR2B	HTR2C	ADRA1D	OPN1SW	RXFP4	RXFP1	OPN1MW	ADRB1	RXFP2	OPN1LW	HTR2A	GRPR	ADRB2	RXFP3	CCR1	ADRA1B	OPN1MW2	HTR4	C3AR1	PTGDR	ADRA1A	PROK2	HRH1	HTR6	PROK1	HTR7	CMKLR1	LHB	HRH3	HRH2	HRH4	DRD1	MC2R	CCR2	DRD2	TRHR	CGA	DRD3	DRD4	MC1R	DRD5	TAAR8	HTR1E	TAAR9	GALR3	GALR2	HTR1F	TAAR6	GALR1	MC4R	GPR39	NPY	HTR1D	FSHB	OPRD1	HTR1A	GPR183	HTR1B	TAAR5	PNOC	TAAR2	GPBAR1	GPR132	MC3R	ADRA2C	HTR5A	TAAR1	TACR2	TACR1	FSHR	ADRA2A	TACR3	NPSR1	GPR143	ADRB3	PTGER4	PTGER2	RGR	CCL3L1	CCL13	CCL3L3	NPS	CXCL1	CCL17	CXCL2	CCL16	GPHA2	CCL25	P2RY11	CCL21	MC5R	GPHB5	OPRM1	GPR4	CYSLTR1	LHCGR	CCL28	CCL27	C3	OPRK1	GPR17	MTNR1A	P2RY13	S1PR1	P2RY10	P2RY14	LTB4R2	RLN2	LPAR4	MTNR1B	RLN3	APP	P2RY6	P2RY4	LPAR6	INSL3	TSHB	P2RY2	ADORA3	PTGIR	AVPR2	P2RY1	ADORA1	KNG1	ADORA2B	TSHR	POMC	TRH	F2R	INSL5	F2	XCL2	XCL1	CX3CR1	PF4	
SARS-COV-1 INFECTION%REACTOME%R-HSA-9678108.2	SARS-CoV-1 Infection	PRKCSH	GANAB	CHMP2B	ST3GAL4	CHMP2A	CHMP4C	MGAT1	CHMP4B	VCP	ST3GAL1	CHMP3	UBA52	ST3GAL2	CHMP4A	ST3GAL3	ST6GAL1	CHMP6	CHMP7	MOGS	ST6GALNAC3	UBB	CTSL	ST6GALNAC4	UBC	RPS27A	CANX	RB1	SUMO1	UBE2I	VHL	MAP1LC3B	ACE2	TMPRSS2	UVRAG	ZCRB1	PARP16	PARP14	PARP10	PARP6	PARP4	PARP9	PARP8	BECN1	DDX5	GSK3B	PIK3R4	GSK3A	PIK3C3	GALNT1	ST6GALNAC2	
SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1%REACTOME DATABASE ID RELEASE 74%1839122	Signaling by activated point mutants of FGFR1	FGF4	FGF6	FGFR1	FGF9	FGF20	FGF1	FGF23	FGF2	
DEFECTIVE SLC7A7 CAUSES LYSINURIC PROTEIN INTOLERANCE (LPI)%REACTOME DATABASE ID RELEASE 74%5660862	Defective SLC7A7 causes lysinuric protein intolerance (LPI)	SLC3A2	SLC7A7	
ARACHIDONATE PRODUCTION FROM DAG%REACTOME DATABASE ID RELEASE 74%426048	Arachidonate production from DAG	ABHD12	DAGLB	DAGLA	MGLL	ABHD6	
SIGNALING BY EGFR%REACTOME%R-HSA-177929.2	Signaling by EGFR	SH3KBP1	AREG	CSK	STAM	SRC	AAMP	PTPN11	HGS	LRIG1	EPS15	UBA52	SH3GL1	SHC1	EGF	PTPN3	GAB1	STAM2	CBL	EGFR	NRAS	PLCG1	SH3GL2	SOS1	HRAS	UBB	SPRY2	PIK3R1	PTPN12	PIK3CA	UBC	HBEGF	PXN	RPS27A	EPGN	EREG	SH3GL3	BTC	TGFA	ADAM10	EPS15L1	ADAM17	CDC42	ADAM12	PAG1	EPN1	PTPRK	SPRY1	ARHGEF7	
POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS%REACTOME%R-HSA-622327.2	Postsynaptic nicotinic acetylcholine receptors	CHRNA5	CHRNA4	CHRNA7	CHRNA6	CHRNA9	CHRND	CHRNG	CHRNE	CHRNA1	CHRNB2	CHRNA3	CHRNB4	CHRNB3	CHRNA2	
G2 M TRANSITION%REACTOME%R-HSA-69275.5	G2 M Transition	CSNK1E	TUBGCP4	TUBG2	DYNLL1	TUBG1	MZT2B	CKAP5	MZT2A	TUBA4A	NME7	PPME1	HAUS2	MZT1	PHLDA1	HAUS1	AKAP9	LCMT1	CEP63	CDK11A	MAPRE1	AJUBA	SFI1	UBA52	OPTN	CCNA2	PAFAH1B1	FBXL18	CCNA1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	CDC25B	DCTN3	CUL1	AURKA	CCNB2	CCNB1	UBB	HAUS8	HAUS7	CENPF	PRKAR2B	UBC	CEP70	CEP72	CEP192	RPS27A	PCNT	CEP76	PPP2CA	CLASP1	CEP78	PPP2CB	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	CDK2	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	WEE1	PPP2R2A	TPX2	HSP90AB1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	CDKN1A	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	CDC25A	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	CDC25C	PSMD13	LIN54	LIN37	PSMB10	LIN9	MYBL2	PSMA7	XPO1	LIN52	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	GTSE1	PSMB9	FKBPL	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	FBXL7	PPP2R1B	FOXM1	PKMYT1	PPP2R3B	CCNH	CEP57	YWHAE	RBBP4	CETN2	CEP164	CCP110	RBX1	PPP1CB	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	BTRC	HMMR	NINL	CEP290	YWHAG	RAB8A	CDK5RAP2	SKP1	CDK7	OFD1	HSP90AA1	BORA	PPP1R12A	CEP135	FBXW11	TUBB	EP300	CEP131	TUBGCP2	MNAT1	HAUS4	HAUS3	CSNK1D	TUBGCP5	TUBGCP6	HAUS6	TP53	TUBGCP3	HAUS5	
SLIT2:ROBO1 INCREASES RHOA ACTIVITY%REACTOME%R-HSA-8985586.1	SLIT2:ROBO1 increases RHOA activity	ROBO1	MYO9B	RHOA	SLIT2	
MTORC1-MEDIATED SIGNALLING%REACTOME%R-HSA-166208.3	mTORC1-mediated signalling	RRAGB	RHEB	AKT1S1	RRAGD	LAMTOR2	LAMTOR1	LAMTOR4	EIF4E	LAMTOR3	EIF4B	LAMTOR5	EIF4G1	YWHAB	RPTOR	RPS6	EEF2K	SLC38A9	MTOR	FKBP1A	EIF4EBP1	RRAGA	RRAGC	RPS6KB1	MLST8	
APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS%REACTOME DATABASE ID RELEASE 74%351906	Apoptotic cleavage of cell adhesion proteins	TJP1	DSG1	CTNNB1	DSG2	CDH1	DSG3	TJP2	CASP3	OCLN	PKP1	DSP	
FORMATION OF SENESCENCE-ASSOCIATED HETEROCHROMATIN FOCI (SAHF)%REACTOME DATABASE ID RELEASE 74%2559584	Formation of Senescence-Associated Heterochromatin Foci (SAHF)	HIST1H1D	LMNB1	HIST1H1E	UBN1	HIST1H1A	HIST1H1B	HIST1H1C	HIRA	RB1	EP400	HMGA2	ASF1A	CABIN1	H1F0	HMGA1	TP53	
FORMATION OF THE BETA-CATENIN:TCF TRANSACTIVATING COMPLEX%REACTOME%R-HSA-201722.4	Formation of the beta-catenin:TCF transactivating complex	HIST2H2AC	H2AFJ	BCL9L	RUVBL1	TLE3	PYGO1	PYGO2	H2AFZ	BCL9	H2AFX	H2AFV	HIST2H2BE	HIST4H4	CTNNB1	TERT	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	MYC	HIST2H4B	RUNX3	SMARCA4	HIST3H3	TRRAP	MEN1	HDAC1	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	AXIN2	RBBP5	HIST2H3A	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	CDC73	HIST1H2BG	ASH2L	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	KMT2D	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	TLE4	HIST1H3A	TLE2	LEO1	TLE1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	LEF1	H3F3B	TCF7	HIST1H4K	HIST1H4L	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	CREBBP	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	TCF7L2	HIST1H4F	HIST2H2AA3	HIST2H2AA4	TCF7L1	
DEFECTIVE SLC9A9 CAUSES AUTISM 16 (AUTS16)%REACTOME%R-HSA-5619052.1	Defective SLC9A9 causes autism 16 (AUTS16)	SLC9A9	
SIGNALING BY TGFB FAMILY MEMBERS%REACTOME%R-HSA-9006936.5	Signaling by TGFB family members	NEDD8	UBE2D1	ACVR1B	ACVR1C	UBA52	AMHR2	ZFYVE16	GDF2	UBB	SMAD9	CCNT1	SMAD5	ACVR2B	BMPR1B	BMPR1A	ACVR2A	UBC	ACVRL1	BMPR2	AMH	CDKN2B	NOG	GREM2	RPS27A	MYC	ARHGEF18	CDK9	PPP1CC	MEN1	BMP10	USP9X	HDAC1	SKI	CCNK	PPP1R15A	RHOA	USP15	NEDD4L	MTMR4	SMAD4	PMEPA1	SMURF2	SMURF1	UCHL5	PPP1CA	SMAD7	BAMBI	STRAP	STUB1	UBE2M	FKBP1A	NCOR2	PPM1A	NCOR1	DRAP1	FSTL1	SKIL	CCNT2	CHRDL1	FST	INHBB	INHBA	FSTL3	CCNC	CER1	CGN	SP1	PRKCZ	FOXH1	CDK8	RBL1	CBL	F11R	E2F4	XPO1	E2F5	WWTR1	PARD3	TRIM33	SNW1	PARP1	TFDP1	ATP1B4	TFDP2	PARD6A	SMAD1	FURIN	SMAD6	SMAD2	SMAD3	TGFB1	TGFBR1	TGFBR2	UBE2D3	PPP1CB	BMP2	TGIF1	TGIF2	SERPINE1	JUNB	RNF111	
VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS%REACTOME DATABASE ID RELEASE 74%432040	Vasopressin regulates renal water homeostasis via Aquaporins	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY5	GNG12	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	AVP	PRKAR2B	PRKACG	PRKACB	AVPR2	GNGT1	GNGT2	ADCY9	PRKAR1B	AQP4	AQP2	PRKAR1A	AQP3	RAB11FIP2	RAB11A	MYO5B	PRKAR2A	PRKACA	GNAS	GNG3	GNG10	GNG2	AQP1	GNG5	GNG4	GNG7	GNG8	ADCY4	ADCY3	
DEFECTIVE CYP26C1 CAUSES FOCAL FACIAL DERMAL DYSPLASIA 4 (FFDD4)%REACTOME DATABASE ID RELEASE 74%5579004	Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4)	CYP26C1	
E2F MEDIATED REGULATION OF DNA REPLICATION%REACTOME%R-HSA-113510.3	E2F mediated regulation of DNA replication	ORC4	POLA2	PPP2CA	ORC6	ORC1	PPP2CB	ORC3	ORC2	MCM8	PPP2R1A	PPP2R3B	CDK1	RB1	TFDP1	TFDP2	PRIM2	CCNB1	PPP2R1B	PRIM1	E2F1	ORC5	POLA1	
PI3K AKT SIGNALING IN CANCER%REACTOME%R-HSA-2219528.1	PI3K AKT Signaling in Cancer	CDKN1A	AREG	CDKN1B	CREB1	FOXO1	PTPN11	PTEN	MDM2	EGF	GAB1	EGFR	KIT	HBEGF	FOXO3	EPGN	KLB	PIK3CD	RAC1	IRS2	FGF1	PIK3CB	FGF2	FGF3	FGF4	VAV1	FGF6	FGF7	FGF9	PDGFRB	ESR1	PDGFRA	CASP9	HGF	ESR2	STRN	NR4A1	IRS1	SRC	TRAT1	PIK3AP1	CD19	FGF20	FGF23	FGF22	ERBB2	FGF16	PRR5	RPS6KB2	CD86	PDPK1	MAPKAP1	CD80	PIK3R3	FGF19	TSC2	PIK3R2	FGF18	RAC2	PIK3R1	MTOR	FGFR4	PIK3CA	LCK	AKT2	FGF10	AKT3	MLST8	BAD	CD28	AKT1	AKT1S1	FYN	RICTOR	RHOG	GSK3B	FRS2	EREG	BTC	NRG1	FOXO6	PDGFB	FOXO4	TGFA	NRG2	NRG3	GSK3A	NRG4	MET	CHUK	
INTESTINAL SACCHARIDASE DEFICIENCIES%REACTOME DATABASE ID RELEASE 74%5659898	Intestinal saccharidase deficiencies	SI	LCT	
GLYCOPROTEIN HORMONES%REACTOME%R-HSA-209822.1	Glycoprotein hormones	FSHB	INHBB	INHBE	INHBA	LHB	CGA	TSHB	INHA	INHBC	
FRS-MEDIATED FGFR4 SIGNALING%REACTOME DATABASE ID RELEASE 74%5654712	FRS-mediated FGFR4 signaling	PTPN11	KLB	FRS2	FGF20	FRS3	FGF1	FGF23	FGF2	FGF4	FGF16	FGF6	NRAS	FGF9	SOS1	FGF19	HRAS	FGF18	FGFR4	
REGULATION OF GENE EXPRESSION IN LATE STAGE (BRANCHING MORPHOGENESIS) PANCREATIC BUD PRECURSOR CELLS%REACTOME DATABASE ID RELEASE 74%210744	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	MAML3	MAMLD1	ONECUT3	ONECUT1	SNW1	NEUROG3	NOTCH1	MAML2	MAML1	KAT2B	HNF1B	RBPJ	KAT2A	CREBBP	EP300	HES1	
PYRIMIDINE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%500753	Pyrimidine biosynthesis	UMPS	DHODH	CAD	
SIGNALING BY MST1%REACTOME DATABASE ID RELEASE 74%8852405	Signaling by MST1	MST1R	SPINT2	SPINT1	HPN	
SYNTHESIS OF DOLICHYL-PHOSPHATE MANNOSE%REACTOME DATABASE ID RELEASE 74%162699	Synthesis of dolichyl-phosphate mannose	DPM1	DPM2	DPM3	
BIOSYNTHESIS OF MARESIN-LIKE SPMS%REACTOME%R-HSA-9027307.1	Biosynthesis of maresin-like SPMs	CYP2C9	CYP2C8	CYP3A4	CYP1A2	CYP2D6	CYP2E1	
NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY%REACTOME%R-HSA-383280.1	Nuclear Receptor transcription pathway	NR4A2	RXRA	NR2C2AP	NR2F1	NR4A1	THRB	NR0B2	THRA	NR2F6	NR2E1	RORC	RORA	NR1H2	RORB	NR1D2	NRBP1	RARG	NR2C2	NR1D1	NR2C1	HNF4A	PGR	RXRB	RXRG	NCOR2	NCOR1	RARA	RARB	VDR	PPARD	MED1	ESRRA	ESRRB	ESRRG	HNF4G	AR	PPARG	PPARA	ESR1	NR5A1	ESR2	
ZBP1(DAI) MEDIATED INDUCTION OF TYPE I IFNS%REACTOME%R-HSA-1606322.1	ZBP1(DAI) mediated induction of type I IFNs	RIPK3	NFKB1	NFKBIA	TICAM1	ZBP1	TBK1	IRF3	NLRP4	RIPK1	DHX9	DTX4	NFKBIB	NFKB2	IKBKB	RELA	TLR3	MYD88	NKIRAS1	NKIRAS2	IKBKG	CHUK	
SYNTHESIS OF PG%REACTOME%R-HSA-1483148.2	Synthesis of PG	PGS1	CDS2	PTPMT1	PLD4	PLD6	PLD1	PLD3	PLD2	
GLYCOGEN METABOLISM%REACTOME DATABASE ID RELEASE 74%8982491	Glycogen metabolism	GYS2	UBA52	PYGB	AGL	GAA	PHKB	PHKA1	PYGM	PYGL	PHKA2	PGM2L1	PHKG1	PHKG2	UBB	PGM2	PPP1R3C	GYG2	NHLRC1	GYG1	UBC	GBE1	RPS27A	EPM2A	PGM1	UGP2	GYS1	
REGULATION OF TP53 EXPRESSION AND DEGRADATION%REACTOME DATABASE ID RELEASE 74%6806003	Regulation of TP53 Expression and Degradation	PHF20	CHEK2	MDM2	DAXX	MDM4	UBA52	CCNA2	CCNA1	PRR5	ATM	RNF34	PDPK1	MAPKAP1	UBB	RFFL	MTOR	UBC	AKT2	AKT3	MLST8	RPS27A	PPP2CA	AKT1	SGK1	PPP2CB	CDKN2A	RICTOR	PPP2R1A	CDK2	CCNG1	PRDM1	CDK1	USP7	PPP2R5C	PPP2R1B	USP2	TP53	
MITOCHONDRIAL FATTY ACID BETA-OXIDATION%REACTOME DATABASE ID RELEASE 74%77289	Mitochondrial Fatty Acid Beta-Oxidation	ACAA2	HADHB	ACOT11	MCAT	HADHA	ACOT12	ACOT13	ACOT2	ACBD7	ACBD6	ACSF2	DBI	MECR	ECHS1	ACSM3	ACSM6	THEM5	HADH	MMAA	ACADS	MUT	THEM4	NDUFAB1	PCCA	PCCB	ACAD11	ACAD10	ACADM	ACADL	ECI1	DECR1	MCEE	ACADVL	PCTP	ACOT9	ACOT7	ACOT1	
INSERTION OF TAIL-ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE%REACTOME DATABASE ID RELEASE 74%9609523	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	ASNA1	UBL4A	SEC61G	EMD	SGTA	SEC61B	HMOX1	GET4	PRNP	CAMLG	VAPA	BAG6	STX5	OTOF	STX1A	APP	SERP1	VAMP2	WRB	
WNT MEDIATED ACTIVATION OF DVL%REACTOME DATABASE ID RELEASE 74%201688	WNT mediated activation of DVL	CSNK1E	DVL1	CSNK2A1	DVL2	DVL3	CSNK2A2	PIP5K1B	CSNK2B	
DOPAMINE NEUROTRANSMITTER RELEASE CYCLE%REACTOME%R-HSA-212676.2	Dopamine Neurotransmitter Release Cycle	APBA1	RIMS1	BZRAP1	UNC13B	RAB3A	PPFIA1	PPFIA4	PPFIA3	PPFIA2	SYT1	CASK	CPLX1	LIN7A	SLC18A2	LIN7C	LIN7B	STX1A	SYN3	SNAP25	SYN1	VAMP2	
PHOSPHOLIPASE C-MEDIATED CASCADE; FGFR4%REACTOME%R-HSA-5654228.2	Phospholipase C-mediated cascade; FGFR4	KLB	FGF20	FGF1	FGF23	FGF2	FGF4	FGF16	FGF6	FGF9	PLCG1	FGF19	FGF18	FGFR4	
CHYLOMICRON REMODELING%REACTOME DATABASE ID RELEASE 74%8963901	Chylomicron remodeling	APOE	APOB	GPIHBP1	APOA2	LPL	APOC3	APOA1	APOA4	APOA5	APOC2	
FREE FATTY ACIDS REGULATE INSULIN SECRETION%REACTOME%R-HSA-400451.1	Free fatty acids regulate insulin secretion	GNA11	GNAQ	ACSL4	PLCB3	FFAR1	ACSL3	PLCB1	PLCB2	CD36	GNA14	GNA15	
PROTON-COUPLED NEUTRAL AMINO ACID TRANSPORTERS%REACTOME%R-HSA-428559.1	Proton-coupled neutral amino acid transporters	SLC36A1	SLC36A2	
DEFECTIVE SLC26A2 CAUSES CHONDRODYSPLASIAS%REACTOME%R-HSA-3560792.2	Defective SLC26A2 causes chondrodysplasias	SLC26A2	
UNCOATING OF THE HIV VIRION%REACTOME DATABASE ID RELEASE 74%162585	Uncoating of the HIV Virion	PPIA	
PEXOPHAGY%REACTOME%R-HSA-9664873.2	Pexophagy	RPS27A	SQSTM1	MAP1LC3B	ATM	USP30	UBB	PEX5	NBR1	UBC	UBA52	EPAS1	
REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION%REACTOME DATABASE ID RELEASE 74%6804758	Regulation of TP53 Activity through Acetylation	BRPF3	PIN1	PIP4K2A	PIP4K2B	PIP4K2C	MEAF6	TMEM55B	CHD4	CHD3	ING5	ING2	AKT2	AKT3	RBBP4	BRD1	PML	AKT1	BRD7	RBBP7	MTA2	MBD3	GATAD2B	MAP2K6	GATAD2A	HDAC2	HDAC1	KAT6A	EP300	BRPF1	TP53	
RESOLUTION OF D-LOOP STRUCTURES%REACTOME DATABASE ID RELEASE 74%5693537	Resolution of D-Loop Structures	DNA2	KAT5	MUS81	ATM	EME1	EME2	GEN1	SLX1B	SPIDR	SLX1A	RTEL1	RAD51AP1	SLX4	BRCA1	XRCC2	BRCA2	XRCC3	NBN	PALB2	TOP3A	RAD51D	BLM	RBBP8	MRE11A	RAD51B	RAD50	RAD51C	RAD51	BRIP1	EXO1	BARD1	RMI2	WRN	RMI1	
INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS%REACTOME DATABASE ID RELEASE 74%177243	Interactions of Rev with host cellular proteins	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	RANGAP1	RCC1	NUP50	XPO1	NUP205	NUP54	POM121	NPM1	RANBP1	AAAS	NUP160	NUP85	TPR	NUP88	KPNB1	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	RAN	NUP107	NUP153	NUP188	
TRANSPORT AND SYNTHESIS OF PAPS%REACTOME DATABASE ID RELEASE 74%174362	Transport and synthesis of PAPS	PAPSS1	PAPSS2	SLC26A2	SLC26A1	SLC35B3	SLC35B2	
NETRIN MEDIATED REPULSION SIGNALS%REACTOME%R-HSA-418886.1	Netrin mediated repulsion signals	UNC5A	UNC5B	UNC5C	SRC	UNC5D	PTPN11	DCC	NTN1	
N-GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS-GOLGI%REACTOME%R-HSA-975576.1	N-glycan antennae elongation in the medial trans-Golgi	B4GALT6	B4GALT4	B4GALT5	FUT8	MGAT5	ST3GAL4	MGAT2	ST6GAL1	MGAT4C	MGAT4A	MGAT4B	MAN2A2	MAN2A1	LHB	CHST8	FUCA1	CHST10	FUT3	CGA	MGAT3	ST8SIA6	B4GALT2	B4GALT1	B4GALT3	ST8SIA2	ST8SIA3	
TOXICITY OF BOTULINUM TOXIN TYPE E (BONT E)%REACTOME%R-HSA-5250992.1	Toxicity of botulinum toxin type E (BoNT E)	SNAP25	SV2B	SV2A	
COPI-DEPENDENT GOLGI-TO-ER RETROGRADE TRAFFIC%REACTOME%R-HSA-6811434.1	COPI-dependent Golgi-to-ER retrograde traffic	RINT1	KIF26A	KIF26B	KIF16B	ZW10	KDELR2	KIF20A	KDELR3	COPG2	KIF20B	COPB2	COPG1	COPA	TMED10	COPB1	KLC1	KLC4	KLC3	KLC2	KIF3B	RACGAP1	RAB1A	KIF3C	SURF4	RAB1B	KIF18A	KIF18B	KIF4B	KIF4A	COPE	ARF3	ARF4	ARF1	KIF11	USE1	KIF15	KIF19	KIF13B	TMED3	KIF1C	TMED2	KIF1B	KIF1A	TMED7	TMED9	KIF25	COPZ2	KIF23	KIF22	ARFGAP3	KIF6	ARFGAP1	KIF27	COPZ1	ARFGAP2	KIF9	KIFC2	KIF2A	KIFC1	KIF2C	KIF2B	SEC22B	ARF5	NAPA	NAPB	NBAS	STX18	NAPG	KDELR1	KIF3A	KIF5B	KIF5A	BNIP1	KIF21A	KIF21B	KIFAP3	NSF	GBF1	ARCN1	CENPE	
GRB2 EVENTS IN ERBB2 SIGNALING%REACTOME%R-HSA-1963640.3	GRB2 events in ERBB2 signaling	EREG	BTC	EGF	NRG1	ERBB2	EGFR	NRG2	NRAS	NRG3	SOS1	NRG4	HRAS	HBEGF	
PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC%REACTOME%R-HSA-389957.2	Prefoldin mediated transfer of substrate to CCT TriC	TUBA1C	TUBA4A	TUBB6	TUBB3	TUBB1	CCT6B	TUBB2B	TUBB2A	VBP1	PFDN1	PFDN2	CCT3	PFDN4	PFDN5	CCT2	PFDN6	CCT7	TUBA1A	CCT6A	TCP1	TUBB4B	CCT8	TUBB4A	CCT5	CCT4	ACTB	
FORMATION OF EDITOSOMES BY ADAR PROTEINS%REACTOME%R-HSA-77042.2	Formation of editosomes by ADAR proteins	ADAR	ADARB1	
REGULATION BY TREX1%REACTOME%R-HSA-3248023.1	Regulation by TREX1	TREX1	
REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS%REACTOME%R-HSA-446388.1	Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	PXN	TESK1	ACTN1	PARVB	RSU1	LIMS1	ARHGEF6	
PHOSPHOLIPID METABOLISM%REACTOME DATABASE ID RELEASE 74%1483257	Phospholipid metabolism	PIP5K1C	RAB14	ARF3	ARF1	PIK3CD	PIK3CB	PIK3CG	PIK3R5	PIP5K1A	PIP5K1B	PIP4K2A	PIP4K2B	PIP4K2C	SACM1L	SBF1	SBF2	OCRL	PTEN	TMEM55B	LPGAT1	CPNE7	PITPNB	CPNE6	LCLAT1	PLB1	LIPI	LIPH	CPNE1	CPNE3	MFSD2A	DGAT2	PCYT2	DGAT1	CSNK2A1	STARD7	HRASLS2	CSNK2A2	PISD	PLA2G15	PLA2G16	GNPAT	PHOSPHO1	GPD2	PLA2G10	GPD1	CSNK2B	PLBD1	HRASLS5	PLA2R1	PLA1A	CDS1	ABHD4	ABHD3	PIK3R3	CHAT	PLA2G3	PIK3R2	PIK3R1	PLD4	PLA2G5	PLD6	PIK3CA	PLA2G6	PLD1	PLD3	PLD2	PGS1	PTDSS2	PTDSS1	PTPMT1	OSBPL8	TMEM86B	CHKB	OSBPL5	CHKA	RARRES3	STARD10	EPT1	DGAT2L6	CRLS1	PEMT	ALPI	PIK3R4	CDS2	SLC44A5	ACHE	SLC44A3	SLC44A4	SLC44A1	SLC44A2	LPCAT1	PCTP	TAZ	OSBPL10	ACP6	FAM73A	FAM73B	PLA2G12A	PLA2G4F	PCYT1B	PCYT1A	PLA2G4D	PLA2G4B	PLA2G4C	PLA2G4A	GPCPD1	HADHB	HADHA	PITPNM1	PITPNM3	PITPNM2	MGLL	AGPAT5	AGPAT6	AGPAT9	PLA2G1B	AGPAT1	AGPAT2	AGPAT3	AGPAT4	AWAT2	GPAT2	CEPT1	RAB5A	CDIPT	PLA2G2F	BCHE	BMX	PLA2G2D	FIG4	PLA2G2E	PNPLA8	VAC14	MTMR2	AGK	MBOAT7	PIKFYVE	MTMR9	PLA2G2A	PIK3C2A	DDHD2	MTM1	MBOAT1	MTMR7	MBOAT2	DDHD1	ETNPPL	GPAM	LPCAT4	ETNK2	LPCAT3	ETNK1	LPCAT2	PNPLA3	CHPT1	GPD1L	LPIN1	LPIN2	LPIN3	PNPLA2	PIK3R6	MTMR4	TNFAIP8	MTMR14	GDE1	PIK3C2G	PIK3C2B	TNFAIP8L1	TNFAIP8L3	TNFAIP8L2	ENPP6	PI4K2B	TPTE2	RUFY1	MTMR10	MTMR1	MTMR12	INPP4A	MTMR3	INPP4B	MTMR8	INPP5F	GDPD1	PI4K2A	TPTE	GDPD3	GDPD5	MTMR6	INPP5J	INPP5K	PLEKHA1	PNPLA7	PLEKHA5	PLEKHA6	PLEKHA3	PLEKHA4	PLEKHA8	PI4KB	PNPLA6	PIK3C3	INPP5D	INPPL1	PTPN13	RAB4A	INPP5E	SYNJ2	SYNJ1	
KIT MUTANTS BIND TKIS%REACTOME DATABASE ID RELEASE 74%9669921	KIT mutants bind TKIs	KIT	
DEX H-BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION%REACTOME%R-HSA-3134963.2	DEx H-box helicases activate type I IFN and inflammatory cytokines production	NFKB1	NFKB2	RELA	MYD88	DHX36	DHX9	IRF7	
MUSCARINIC ACETYLCHOLINE RECEPTORS%REACTOME%R-HSA-390648.1	Muscarinic acetylcholine receptors	CHRM2	CHRM3	CHRM1	CHRM4	CHRM5	
DETOXIFICATION OF REACTIVE OXYGEN SPECIES%REACTOME DATABASE ID RELEASE 74%3299685	Detoxification of Reactive Oxygen Species	NOX4	NOX5	GSTP1	ATP7A	CYBA	ERO1L	GPX2	PRDX2	PRDX1	SOD2	P4HB	NCF1	GPX3	NCF2	GPX6	NCF4	GPX5	GPX8	GPX7	TXNRD1	CYBB	ATOX1	GPX1	AQP8	TXN	NUDT2	CAT	CYCS	TXN2	PRDX3	SOD3	SOD1	PRDX6	CCS	
CTLA4 INHIBITORY SIGNALING%REACTOME%R-HSA-389513.1	CTLA4 inhibitory signaling	PPP2CA	AKT1	PPP2CB	FYN	PTPN11	PPP2R1A	PPP2R5E	YES1	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	CD86	LYN	CTLA4	CD80	PPP2R1B	LCK	AKT2	AKT3	
PEPTIDE HORMONE METABOLISM%REACTOME DATABASE ID RELEASE 74%2980736	Peptide hormone metabolism	INHBB	INHBA	GATA4	ISL1	GNG13	GCG	ERO1L	GNB3	CPA3	CTNNB1	ENPEP	ACE	CPB1	MME	ATP6AP2	STX1A	C9orf3	BCHE	GZMH	GNAT3	ANPEP	CTSG	REN	CES1	CTSD	LHB	CRHR2	CGA	INHA	IGF1	INHBC	FSHB	INHBE	RAB27A	CTSZ	VAMP2	CPB2	MBOAT4	PCSK1	PLA2G7	CDX2	GRP	CMA1	GPR119	DPP4	SPCS3	SPCS2	PCSK2	MYO5A	SPCS1	ERO1LB	FFAR4	KIF5C	FFAR1	ACE2	SLC30A7	SEC11A	SLC30A6	INS	SEC11C	SLC30A8	KLF4	SLC30A5	MYRIP	UCN	TMEM27	LEP	CPE	PAX6	TSHB	EXOC8	POMC	EXOC7	GH1	GIP	EXOC4	EXOC3	EXOC6	KIF5B	EXOC5	KIF5A	ACHE	EXOC2	EXOC1	AGT	TCF7L2	
ADENYLATE CYCLASE INHIBITORY PATHWAY%REACTOME DATABASE ID RELEASE 74%170670	Adenylate cyclase inhibitory pathway	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY9	ADCY5	GNAL	GNAI3	GNAT3	ADCY4	GNAI1	ADCY3	GNAI2	
AURKA ACTIVATION BY TPX2%REACTOME DATABASE ID RELEASE 74%8854518	AURKA Activation by TPX2	CSNK1E	DYNLL1	TUBG1	CKAP5	TUBA4A	HAUS2	HAUS1	AKAP9	CEP63	MAPRE1	SFI1	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	AURKA	HAUS8	HAUS7	PRKAR2B	CEP70	CEP72	CEP192	PCNT	CEP76	CLASP1	CEP78	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	TPX2	CEP57	YWHAE	CETN2	CEP164	CCP110	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	HMMR	NINL	CEP290	YWHAG	CDK5RAP2	OFD1	HSP90AA1	CEP135	TUBB	CEP131	HAUS4	HAUS3	CSNK1D	HAUS6	HAUS5	
NONCANONICAL ACTIVATION OF NOTCH3%REACTOME%R-HSA-9017802.1	Noncanonical activation of NOTCH3	NOTCH3	YBX1	PSEN2	NCSTN	APH1A	APH1B	PSENEN	PSEN1	
TRANSPORT OF SMALL MOLECULES%REACTOME%R-HSA-382551.5	Transport of small molecules	SLC34A1	SLC9A2	SLC9A3	SLC9A4	ABCA12	SLC5A8	SLC9A5	ABCG8	SLC9A6	ABCG5	ABCA10	SLC9A7	SLC9A8	ABCG4	SLC9A9	CFTR	SLC26A2	ABCG1	SLC26A1	VCP	UBA52	ABCB1	SLC1A1	ABCB6	SLC1A2	ABCB7	SLC1A4	ABCB4	SLC1A5	ABCB5	SLC1A6	SEL1L	SLC1A7	ABCB8	SLC9A1	ABCB9	SLC5A5	ABCA2	CUL1	SLC15A3	ABCA5	SLC38A3	ABCA6	LETM1	SLC15A4	ABCA3	SLC38A2	VDAC3	ABCA4	SLC38A5	VDAC2	UBB	ABCA9	SLC38A4	VDAC1	ERLIN1	SLC4A10	PRKAR2B	SLC16A10	ABCA7	ERLIN2	SLC26A7	UBC	ABCA8	SLC26A9	SLC26A4	EIF2S2	SLC26A3	EIF2S1	RPS27A	SLC26A6	EIF2S3	RNF185	SLC7A11	SLC7A10	ABCD2	SLC36A1	ABCD3	ABCC10	SLC36A2	ABCC11	SLC32A1	SLC7A5	AQP4	ABCD1	SLC25A18	AQP2	ABCC3	SLC7A6	AQP3	ABCC4	SLC7A7	RAB11FIP2	ABCC1	SLC7A8	MYO5B	ABCC2	SLC25A10	ABCC5	SLC24A2	ABCC6	APOA1	SLC24A1	SLC24A4	ABCC9	SLC24A3	PEX3	SLC20A2	DERL3	SLC43A2	DERL1	SLC20A1	DERL2	SLC43A1	RNF5	SLC5A12	ERLEC1	OS9	SLC3A2	SLC7A1	ABCF1	SLC7A3	PEX19	SLC25A26	KCNJ11	ABCB10	SLC25A29	SLC17A6	SLC17A7	SLC17A8	SLC17A1	SLC25A22	SLC36A4	CTNS	SLC8B1	SLC4A7	SLC8A3	SLC4A8	SLC4A9	SLC24A5	HBA2	HBA1	SLC30A7	SLC30A6	SLC30A8	SLC30A5	SLC2A4	SGK1	SLC2A8	TUSC3	MAGT1	SLC5A9	SLC30A10	SLC5A4	EMB	SLC2A14	SLC2A11	SLC2A12	NIPA1	SLC39A10	NIPA2	SLC39A14	DMTN	SLC39A6	SLC16A7	SLC39A5	SLC39A8	SLC39A7	SLC39A2	SLC39A1	CYB5R1	SLC39A3	SLC14A1	SLC14A2	PIP	MB	SLC13A1	SLC13A2	SLC13A3	SLC13A4	NGB	SLC47A2	SLC47A1	SLC5A10	LRRC8C	LRRC8D	LRRC8A	LRRC8B	SLC13A5	LRRC8E	AQP6	AQP5	NIPAL4	NIPAL1	SLC35B3	NIPAL2	SLC35B2	NIPAL3	SLC35B4	AZGP1	MIP	SLC35D1	SLC45A3	SLC35D2	SLCO1B1	ANKH	SLC10A6	PDZD11	SLCO2B1	KIAA1919	SLCO1B3	MRS2	SLC16A2	SLC31A1	SLC35A2	SLC30A3	SLC35A1	SLC30A2	SLC35A3	MMGT1	SLC33A1	SLC30A1	SLC35C1	SLC41A2	SLCO1C1	SLC41A1	SLC5A6	PQLC2	ARL2BP	AQP10	SLCO4A1	SLC2A6	SLCO4C1	SLC2A7	SLCO1A2	AQP12A	SLCO2A1	SLC34A2	ADD3	SLC29A4	CYGB	AVP	ADD2	SLC29A1	SLC50A1	SLC28A2	AQP11	SLC28A1	SLC29A3	SLC28A3	SLC29A2	SLC11A1	PRKACG	PRKACB	ADCY9	PRKAR1B	PRKAR1A	PRKAR2A	SLC44A5	GNAS	SLC44A3	SLC44A4	SLC44A1	SLC44A2	ADCY4	ADCY3	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY5	RSC1A1	SLC5A1	ARL2	PHB	NEDD4L	CLCN6	SLC5A7	CAMK2B	CAMK2D	CAMK2G	SLC22A5	SLC2A1	CLTC	CLTA	CA1	ATP8A2	ATP8A1	ATP12A	BEST2	BEST3	SLC9C1	SLC9C2	BEST1	BEST4	SLN	ATP11C	ATP11B	ATP11A	TRPC4AP	SLC9B1	SLC9B2	SCNN1G	SCNN1D	SCNN1B	SCNN1A	TTYH3	TTYH2	CLCNKB	WNK4	CLCNKA	NALCN	TRPM1	TRPM2	ASIC4	ASIC5	CLCA2	CLCA1	TRPM7	TRPM8	ASIC2	TRPM5	TRPM6	ASIC3	CLCA4	TRPM3	ASIC1	TRPM4	ATP8B4	ATP8B3	ATP8B2	ATP8B1	TRPV2	TRPV3	TRPV1	SLC25A5	ATP4B	SLC25A4	ATP4A	SLC25A6	TRPV6	WNK1	WNK2	TRPV4	WNK3	TRPV5	CUTC	RYR1	RYR2	ATP2A3	ATP2A2	ATP2A1	RYR3	UNC80	ATP7B	CLIC2	ATP7A	TSC22D3	ANO8	ANO9	ANO6	ANO7	STOML2	ANO4	CCDC109B	ANO5	SPG7	PHB2	ANO2	TRDN	PARL	AFG3L2	ANO3	C2orf47	ANO1	SMDT1	ASPH	PMPCB	SGK3	YME1L1	SGK2	PMPCA	STOML3	ATP10D	MICU3	ATP10B	MICU2	ATP10A	MICU1	MCU	ATP2C2	SRI	CLCN3	ATP2C1	CLCN2	SLC39A4	CLCN1	SLC5A2	PLN	SLC2A10	BSND	ANO10	SLC16A1	STOM	RHAG	ATP9B	SLC17A3	ATP9A	MCOLN3	TRPA1	ATP13A1	ATP2B4	RAB11A	ATP2B3	ATP2B2	ATP2B1	MCOLN2	TPCN2	TPCN1	CLCN7	CLCN5	CLCN4	PSMD8	OSTM1	SLC22A12	FKBP1B	PSMD9	ATP13A4	PSMD6	ATP13A5	PSMD7	SLC2A9	ATP13A2	PSMD4	UNC79	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	ADD1	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	SLC6A19	PSMC5	AQP8	SLC6A18	PSMC6	SLC22A2	PSMC3	SLC6A15	PSMC4	SLC22A1	PSMC1	SLC6A14	PSMC2	SLC6A13	SLC6A12	SLC6A11	SLC6A1	SLC6A2	SLC6A3	SLC6A5	SLC16A8	SLC6A6	SLC16A3	SLC6A7	SLC6A9	SLC18A1	SLC18A2	LCN9	SLC27A1	AQP1	LCN15	CYB5R2	LCN12	CYB5R4	LCN1	SLC27A6	CA2	APOD	CA4	CYB5RL	SLC27A4	SLC7A9	SLC3A1	GNGT1	GNGT2	SLC46A1	STEAP3	TFRC	CAMK2A	HFE	SLC40A1	TCIRG1	HEPH	SLC22A17	SLC17A5	FTH1	ATP6V1E1	GNG3	ATP6V1E2	GNG10	ATP6V0B	ATP6V1G1	GNG2	ATP6V0E1	ATP6V1G2	GNG5	GLRX3	GNG4	ATP6AP1	GNG7	SLC11A2	GNG8	TFR2	ATP6V1B2	ATP6V0D1	STEAP2	ATP6V0D2	ATP6V0C	RAF1	ATP6V1B1	ABCG2	FTL	ATP6V1A	IREB2	GNG12	NEDD8	GNG11	CAND1	GNG13	FTMT	ATP6V0A2	ATP6V1H	HMOX1	ATP6V0A4	ATP6V1G3	ATP6V0E2	GNB2	ATP6V1D	ATP6V1C1	GNB1	HMOX2	ATP6V1C2	GNB4	ATP6V0A1	GNB3	ATP6V1F	CYBRD1	GNB5	MCOLN1	CP	TF	LCN2	ACO1	FBXL5	HBB	WWP1	AKAP1	SLC22A18	SLC6A20	SLC12A2	SLC12A3	SLC12A4	SLC12A5	SLC12A1	SLC12A6	SLC12A7	SLC2A2	BSG	A2M	AQP9	AQP7	HDLBP	PCSK9	AP2A1	ZDHHC8	VLDLR	PCSK6	AP2A2	LIPA	TRPC7	TRPC5	PCSK5	LIPC	CREB3L3	TRPC6	LIPG	LDLRAP1	TRPC3	AP2M1	CUBN	TRPC4	MYLIP	AMN	TRPC1	APOA2	LSR	APOA4	APOA5	SOAT1	NPC1	SOAT2	NPC2	ANGPTL3	ANGPTL4	LPA	CES3	CETP	SAR1B	C19orf80	MTTP	FURIN	LPL	LCAT	LMF2	LMF1	AP2S1	APOF	APOE	APOB	LDLR	FGF21	GPIHBP1	SLC2A3	ABCA1	MBTPS1	NR1H2	APOC4	APOBR	ATP1B3	APOC3	ATP1B2	NR1H3	SLC1A3	AP2B1	ATP1B1	NCEH1	APOC2	ALB	APOC1	ATP1A4	P4HB	ATP1A3	ATP1A2	MBTPS2	ATP1A1	RHCG	RHBG	FXYD4	FXYD3	AVPR2	RUNX1	FXYD2	FXYD1	FXYD7	FXYD6	SLC2A13	SLC5A11	PRKACA	SLC5A3	SLC22A4	SLC22A3	SLC22A6	SLC22A15	SLC22A16	SKP1	SLC22A8	AHCYL2	SLC22A7	SLC4A1	SLC22A11	SLC4A2	SLC4A3	SLC4A4	SLC4A5	SLC8A1	SLC8A2	SLC26A11	SLC34A3	SLC38A1	SLC15A1	SLC15A2	
SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE%REACTOME DATABASE ID RELEASE 74%1660514	Synthesis of PIPs at the Golgi membrane	PIK3C2A	TPTE2	PI4K2B	INPP5E	ARF3	TPTE	PI4K2A	ARF1	SACM1L	PIK3R4	PI4KB	PIK3C3	PIK3C2G	FIG4	VAC14	OCRL	PIKFYVE	
ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%390471	Association of TriC CCT with target proteins during biosynthesis	LONP2	XRN2	DCAF7	CCT6B	KIF13A	FBXO4	FBXO6	CCNE2	FBXW4	CCNE1	FBXW5	FBXW10	FBXW7	SPHK1	FBXW9	NOP56	FBXW2	FBXL5	CCT3	FKBP9	CCT2	USP11	GBA	AP3M1	CCT7	ARFGEF2	CCT6A	FBXL3	TCP1	SKIV2L	CCT8	WRAP53	CCT5	STAT3	CCT4	HDAC3	GAPDHS	TP53	
DRUG RESISTANCE IN ERBB2 KD MUTANTS%REACTOME DATABASE ID RELEASE 74%9665230	Drug resistance in ERBB2 KD mutants	ERBB2	HSP90AA1	CDC37	ERBB2IP	
LXRS REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS%REACTOME%R-HSA-9029558.1	LXRs regulate gene expression linked to lipogenesis	RXRA	RXRB	ANGPTL3	SCD	NRIP1	NR1H2	FASN	NR1H3	
NUCLEOTIDE SALVAGE%REACTOME%R-HSA-8956321.1	Nucleotide salvage	ADA	CDA	TK2	TK1	HDHD1	GMPR2	ADK	GMPR	UCKL1	AMPD1	AMPD2	UCK2	AMPD3	UCK1	DCK	TYMP	APRT	ADAL	DGUOK	UPP2	PNP	UPP1	HPRT1	
TOLERANCE OF REACTIVE OXYGEN PRODUCED BY MACROPHAGES%REACTOME%R-HSA-1222387.2	Tolerance of reactive oxygen produced by macrophages	
ATF6 (ATF6-ALPHA) ACTIVATES CHAPERONE GENES%REACTOME%R-HSA-381183.2	ATF6 (ATF6-alpha) activates chaperone genes	ATF4	HSPA5	NFYA	CALR	NFYB	NFYC	HSP90B1	DDIT3	ATF6	
SYNTHESIS OF HEPOXILINS (HX) AND TRIOXILINS (TRX)%REACTOME%R-HSA-2142696.1	Synthesis of Hepoxilins (HX) and Trioxilins (TrX)	ALOX12	
STABILIZATION OF P53%REACTOME%R-HSA-69541.5	Stabilization of p53	PSMA6	PSMA3	PSMA4	PSMA1	PHF20	PSMA2	CHEK2	PSME3	PSME4	PSME1	PSME2	PSMD10	MDM2	PSMB11	MDM4	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	RFWD2	ATM	CDKN2A	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	TP53	
TRAFFICKING OF GLUR2-CONTAINING AMPA RECEPTORS%REACTOME DATABASE ID RELEASE 74%416993	Trafficking of GluR2-containing AMPA receptors	PRKCG	GRIA1	GRIA2	PRKCB	TSPAN7	PRKCA	NSF	GRIP1	GRIA3	AP2A1	GRIA4	PICK1	
CELL RECRUITMENT (PRO-INFLAMMATORY RESPONSE)%REACTOME DATABASE ID RELEASE 74%9664424	Cell recruitment (pro-inflammatory response)	ENTPD5	NFKB1	NT5E	TXNIP	P2RX7	TXN	MEFV	P2RX4	SUGT1	PYCARD	HSP90AB1	IL18	C3	NFKB2	RELA	NLRP3	IL1A	IL1B	PSTPIP1	CASP1	C3AR1	CTSG	ENTPD1	
SIGNALING BY PDGF%REACTOME%R-HSA-186797.4	Signaling by PDGF	STAT6	PTPN11	COL9A1	COL9A3	COL9A2	NRAS	PLCG1	SOS1	HRAS	PTPN12	STAT5A	STAT5B	PIK3CB	CRKL	RAPGEF1	NCK1	PDGFRB	PDGFRA	PLG	FURIN	SPP1	SRC	COL4A2	COL4A1	COL6A2	COL4A4	THBS1	COL4A3	GRB7	COL6A1	COL6A3	COL4A5	PIK3R2	PIK3R1	COL6A6	PIK3CA	COL6A5	PLAT	CRK	THBS4	THBS3	BCAR1	THBS2	PDGFD	NCK2	STAT1	STAT3	PDGFB	RASA1	
DEFECTIVE ABCB11 CAUSES PFIC2 AND BRIC2%REACTOME DATABASE ID RELEASE 74%5678520	Defective ABCB11 causes PFIC2 and BRIC2	ABCB11	
SEROTONIN NEUROTRANSMITTER RELEASE CYCLE%REACTOME%R-HSA-181429.2	Serotonin Neurotransmitter Release Cycle	RIMS1	BZRAP1	UNC13B	RAB3A	PPFIA1	PPFIA4	PPFIA3	PPFIA2	SYT1	CPLX1	SLC18A2	STX1A	SYN3	SNAP25	SYN1	VAMP2	
LECTIN PATHWAY OF COMPLEMENT ACTIVATION%REACTOME DATABASE ID RELEASE 74%166662	Lectin pathway of complement activation	FCN1	MBL2	COLEC11	MASP1	FCN2	COLEC10	FCN3	
CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM%REACTOME%R-HSA-1793185.1	Chondroitin sulfate dermatan sulfate metabolism	CHST7	CHPF2	B4GALT7	CHST3	CHSY1	CHSY3	B3GAT2	B3GAT1	SDC2	IDUA	HEXB	NCAN	HEXA	BGN	VCAN	HYAL1	HYAL3	IDS	DCN	SDC4	CSPG5	B3GAT3	CSPG4	SDC3	ARSB	GPC3	SDC1	GPC2	GPC5	GPC4	GPC6	AGRN	GPC1	CHPF	XYLT2	XYLT1	CSGALNACT1	CSGALNACT2	CHST11	CHST12	DSEL	CHST15	CHST13	CHST14	B3GALT6	HSPG2	BCAN	UST	DSE	
INFLUENZA VIRUS INDUCED APOPTOSIS%REACTOME%R-HSA-168277.5	Influenza Virus Induced Apoptosis	TGFB1	SLC25A6	
SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS%REACTOME%R-HSA-391160.2	Signal regulatory protein family interactions	SKAP2	PTPN6	CD47	SIRPB1	PTPN11	PTK2B	SIRPG	PTK2	TYROBP	SIRPA	FYB	
CD22 MEDIATED BCR REGULATION%REACTOME DATABASE ID RELEASE 74%5690714	CD22 mediated BCR regulation	IGKV2-28	IGKV1-12	IGKV3D-20	CD22	IGKV2D-28	IGKV4-1	IGKV2D-30	PTPN6	IGKV3-11	LYN	IGKV5-2	CD79B	CD79A	
PHOSPHORYLATION OF EMI1%REACTOME DATABASE ID RELEASE 74%176417	Phosphorylation of Emi1	FZR1	CDC20	CCNB1	PLK1	CDK1	FBXO5	
FGFRL1 MODULATION OF FGFR1 SIGNALING%REACTOME DATABASE ID RELEASE 74%5658623	FGFRL1 modulation of FGFR1 signaling	FGF4	FGFRL1	SPRED2	SPRED1	FGF18	FGF23	FGF10	FGF2	FGF22	FGF3	
PDE3B SIGNALLING%REACTOME%R-HSA-165160.3	PDE3B signalling	PDE3B	AKT2	
SIGNALING BY FGFR3%REACTOME DATABASE ID RELEASE 74%5654741	Signaling by FGFR3	MAPK3	PTPN11	FGF20	UBA52	FGF23	GAB1	CBL	FGF16	NRAS	PLCG1	SOS1	MKNK1	HRAS	UBB	FGF18	SPRY2	PIK3R1	GALNT3	PIK3CA	UBC	RPS27A	PPP2CA	PPP2CB	MAPK1	PPP2R1A	FRS2	FRS3	FGF1	FGF2	FGF4	FGF9	BRAF	
PLASMALOGEN BIOSYNTHESIS%REACTOME%R-HSA-75896.2	Plasmalogen biosynthesis	AGPS	GNPAT	DHRS7B	
JNK (C-JUN KINASES) PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1%REACTOME DATABASE ID RELEASE 74%450321	JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	MAP2K4	RIPK2	MAPK10	TRAF6	IRAK1	UBE2V1	MAP2K7	UBE2N	TAB3	TAB2	NOD1	TAB1	NOD2	IKBKG	MAPK9	MAP3K7	MAPK8	IRAK2	
TRANSPORT OF CONNEXINS ALONG THE SECRETORY PATHWAY%REACTOME%R-HSA-190827.2	Transport of connexins along the secretory pathway	GJB2	GJB1	GJA1	
METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS%REACTOME DATABASE ID RELEASE 74%6799990	Metal sequestration by antimicrobial proteins	S100A7A	LTF	S100A9	LCN2	S100A8	S100A7	
RMTS METHYLATE HISTONE ARGININES%REACTOME DATABASE ID RELEASE 74%3214858	RMTs methylate histone arginines	HIST2H2AC	DNMT3A	H2AFJ	H2AFZ	SMARCD1	H2AFX	PRMT1	H2AFV	SMARCD2	HIST4H4	SMARCE1	ACTL6B	CARM1	WDR5	ACTL6A	HIST2H4A	RPS2	HIST2H2AB	HIST2H4B	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	HIST1H2AI	HIST1H2AH	SMARCA4	PRMT6	HIST1H2AK	SMARCB1	HIST3H2A	JAK2	SMARCC1	SMARCC2	HIST1H2AE	HIST1H2AD	SMARCD3	HIST1H2AC	HIST1H2AB	HIST1H2AJ	ARID1A	ARID1B	HIST2H3A	PRMT3	SMARCA2	HIST2H3D	PBRM1	HIST2H3C	H2AFB1	HIST1H3J	ARID2	PRMT5	HIST1H3A	HIST1H3F	HIST1H3G	HIST1H3H	RBBP7	HIST1H3I	PRMT7	HIST1H3B	HIST1H3C	COPRS	HIST1H3D	HIST1H3E	CCND1	HIST1H4K	CDK4	HIST1H4L	WDR77	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
P75NTR RECRUITS SIGNALLING COMPLEXES%REACTOME%R-HSA-209543.1	p75NTR recruits signalling complexes	RPS27A	SQSTM1	RIPK2	NGF	NGFR	TRAF6	UBA52	IRAK1	IKBKB	MYD88	PRKCI	UBB	UBC	
SIGNALING BY BMP%REACTOME DATABASE ID RELEASE 74%201451	Signaling by BMP	UBE2D1	CER1	SMAD4	SMURF2	SMURF1	SMAD7	AMHR2	ZFYVE16	GDF2	SMAD9	ACVR2B	SMAD5	BMPR1B	ACVR2A	BMPR1A	ACVRL1	UBE2D3	BMPR2	AMH	NOG	GREM2	FSTL1	BMP2	BMP10	SKI	CHRDL1	SMAD1	SMAD6	
OLFACTORY SIGNALING PATHWAY%REACTOME DATABASE ID RELEASE 74%381753	Olfactory Signaling Pathway	OR11A1	OR8A1	OR8I2	OR52N1	OR52N5	OR52N4	OR52N2	OR5D18	OR10W1	OR2A42	OR5D16	OR5D14	OR5D13	OR8H3	OR8H2	OR8H1	OR52M1	OR10V1	OR4C12	OR6C6	OR4C11	OR6C4	OR6C3	OR4C16	OR8G5	OR6C2	OR4C15	OR5AK2	OR6C1	OR4C13	OR8G1	OR10T2	OR52L1	OR6B3	OR6B2	OR6B1	OR2A25	OR10S1	OR52K2	OR52K1	OR2A12	OR6A2	OR2A14	OR2A1	OR4E2	OR4D9	OR5AP2	OR5B12	OR4D6	OR4D5	OR5B17	OR4D2	OR4D1	OR10Z1	OR52R1	OR4C6	OR4C5	OR4A15	OR4C3	OR4A16	OR8K5	OR8K3	OR8K1	OR5AN1	OR4B1	OR4C46	OR6F1	OR8J3	OR8J1	OR10X1	OR4A5	OR6M1	OR2T12	OR2T10	OR2T11	OR5H15	OR5H14	OR2D3	OR2D2	OR52E4	OR52E2	OR5AC2	OR52E8	OR52E6	OR52E5	OR2C3	OR6K6	OR2C1	OR6K3	OR6K2	OR52D1	OR2B6	OR4F6	OR2B3	OR4F5	OR2B2	OR10K2	OR4F4	OR4F3	OR10K1	OR6J1	OR2A7	OR2A5	OR2A4	OR2A2	OR52J3	OR4M2	OR4M1	OR10R2	OR6Q1	OR8U1	OR52I2	OR52I1	OR2H2	OR2H1	OR4L1	OR6P1	OR10Q1	OR2G6	OR52H1	OR2G3	OR4K5	OR2G2	OR4K2	OR4K1	OR10P1	OR2T34	OR8S1	OR2T35	OR2T33	OR2T27	OR2F2	OR2F1	OR2T29	OR6N2	OR6N1	GNAL	OR2M7	OR2M5	OR2M4	OR2M3	OR4K17	OR2M2	OR4Q3	OR2L8	OR2L5	OR2L3	OR4P4	OR2L2	OR10AD1	OR6T1	OR4K15	OR4K14	OR4K13	OR2K2	OR6S1	OR10D3	OR8B12	OR14K1	OR4N5	OR2J3	OR4N4	OR2J2	OR2J1	OR4N2	OR10C1	OR10J1	OR10J3	OR10J5	OR6Y1	OR52B2	OR52B6	OR6X1	OR52A1	OR52A5	OR10H1	OR10H3	OR10H2	OR10H5	OR10H4	OR4S2	OR4S1	OR10G2	OR14A16	OR10G4	OR10G3	OR6V1	OR10G6	OR10G8	OR10G7	OR10G9	OR14C36	OR2T8	OR2T7	OR2T6	OR2T5	OR2T4	OR2T3	OR2T2	OR2T1	OR4X2	OR4X1	OR9A4	OR51T1	OR9A2	OR2S2	OR51S1	OR7E24	OR7A10	OR14J1	OR2Y1	OR56B1	OR56B4	OR7A17	OR14I1	OR10A7	OR56A5	OR7A5	OR10A2	OR56A4	OR10A4	OR10A3	OR56A3	OR10A6	GNGT1	OR10A5	OR56A1	OR2W3	OR2W1	OR12D3	OR12D2	OR51V1	OR2V2	OR2V1	OR7G2	OR7G1	OR9K2	OR51L1	OR5B3	OR5B2	OR2AT4	OR5A2	OR5A1	OR9I1	OR51J1	OR7D4	OR7D2	OR51I2	GNB1	OR51I1	OR4D11	OR4D10	OR2Z1	OR9G4	OR7C2	OR7C1	OR9G1	OR51Q1	OR5F1	OR3A3	OR14A2	OR3A2	OR3A1	OR51M1	OR5C1	OR7G3	OR1C1	OR5K4	OR5K3	OR5K2	OR51D1	OR5K1	OR1B1	OR5J2	OR1A2	OR1A1	OR51B2	OR5I1	OR9Q2	OR9Q1	OR2AK2	OR51B6	OR51B5	OR51B4	OR5H6	OR5H2	OR5H1	OR2AJ1	OR51A4	OR51A2	OR51A7	RTP4	RTP5	RTP2	OR51H1	RTP3	RTP1	OR1G1	OR10AG1	OR51G2	OR51G1	OR1F1	OR2AP1	OR2B11	OR51F2	OR51F1	OR5M9	OR5M8	OR1E2	OR1E1	OR5M3	OR5M1	OR4F29	OR4F21	OR51E1	OR1D5	OR1D2	OR51E2	OR5L2	OR5L1	OR4F17	OR4F16	OR4F15	OR11H2	OR11H1	OR11H4	OR1K1	OR2AE1	OR11H6	OR1J4	OR11G2	OR1J2	OR1J1	OR5R1	OR13J1	OR1I1	OR5M11	OR5M10	OR5P3	OR5P2	OR11L1	OR5W2	OR1N2	OR1N1	OR5V1	OR1M1	OR2AG1	OR2AG2	OR1L8	OR1L6	OR1L4	OR1L3	OR1L1	OR5T3	OR5T2	OR5T1	OR52W1	OR1S2	OR1S1	OR13D1	OR5AS1	OR13C9	OR13C8	OR2L13	OR13C3	OR13C2	OR13C5	OR13C4	OR5AR1	OR1Q1	OR4A47	OR5B21	REEP1	REEP5	REEP4	REEP3	REEP2	REEP6	OR13A1	OR13H1	OR8D4	OR8D2	OR8D1	OR6C70	OR6C76	OR6C75	OR6C74	OR13G1	OR6C65	OR8B8	OR8B4	OR6C68	OR13F1	OR8B3	OR8B2	OR5AU1	
DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM%REACTOME DATABASE ID RELEASE 74%3560782	Diseases associated with glycosaminoglycan metabolism	AGRN	B4GALT7	GPC1	CHST3	CHSY1	SLC26A2	ST3GAL3	SDC2	CHST6	HEXB	NCAN	HEXA	BGN	VCAN	DCN	SDC4	CSPG5	B3GAT3	CSPG4	SDC3	GPC3	SDC1	GPC2	CHST14	LUM	GPC5	B3GALT6	OGN	GPC4	OMD	HSPG2	EXT1	PRELP	GPC6	EXT2	BCAN	KERA	FMOD	B4GALT1	PAPSS2	
RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE%REACTOME%R-HSA-77075.2	RNA Pol II CTD phosphorylation and interaction with CE	RNMT	CCNH	RNGTT	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	SUPT5H	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	CDK7	ERCC3	ERCC2	MNAT1	
CRMPS IN SEMA3A SIGNALING%REACTOME DATABASE ID RELEASE 74%399956	CRMPs in Sema3A signaling	FYN	CRMP1	PLXNA2	PLXNA1	GSK3B	PLXNA4	CDK5R1	PLXNA3	NRP1	FES	CDK5	DPYSL4	DPYSL5	DPYSL2	DPYSL3	SEMA3A	
DEGRADATION OF CYSTEINE AND HOMOCYSTEINE%REACTOME%R-HSA-1614558.6	Degradation of cysteine and homocysteine	TSTD1	MPST	CSAD	ADO	ETHE1	GOT2	SUOX	SLC25A10	CTH	CDO1	GADL1	TXN2	SQRDL	TST	
POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION%REACTOME%R-HSA-5250913.4	Positive epigenetic regulation of rRNA expression	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	SMARCA5	HIST4H4	DDX21	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HDAC2	HDAC1	SF3B1	CBX3	POLR2E	POLR2F	POLR2H	POLR2K	POLR2L	DEK	BAZ1B	TBP	POLR1C	ACTB	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	EHMT2	H2AFB1	CHD4	HIST1H3J	CHD3	TTF1	TAF1D	ZNRD1	HIST1H3A	MTA1	RBBP4	MYBBP1A	TAF1B	HIST1H3F	TAF1C	HIST1H3G	TWISTNB	TAF1A	HIST1H3H	HIST1H3I	RBBP7	HIST1H3B	MTA2	HIST1H3C	MTA3	HIST1H3D	MBD3	CD3EAP	HIST1H3E	GSK3B	H3F3B	HIST1H4K	HIST1H4L	GATAD2B	GATAD2A	KAT2B	H3F3A	KAT2A	H2BFS	HIST1H4A	POLR1A	HIST1H4B	POLR1B	HIST1H4H	HIST1H4I	POLR1E	HIST1H4J	ERCC6	EP300	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS%REACTOME DATABASE ID RELEASE 74%9614399	Regulation of localization of FOXO transcription factors	FOXO6	YWHAQ	YWHAB	FOXO4	AKT1	SFN	FOXO3	FOXO1	YWHAZ	AKT2	AKT3	YWHAG	
MAPK TARGETS  NUCLEAR EVENTS MEDIATED BY MAP KINASES%REACTOME%R-HSA-450282.1	MAPK targets  Nuclear events mediated by MAP kinases	RPS6KA1	MAPK3	FOS	CREB1	DUSP4	DUSP6	DUSP7	ATF1	ATF2	MAPKAPK2	ELK1	MAPK9	MAPK8	MAPK7	MEF2A	MEF2C	PPP2CA	MAPK10	PPP2CB	VRK3	MAPK1	PPP2R1A	MAPK14	MAPK11	PPP2R5D	JUN	PPP2R1B	RPS6KA3	RPS6KA5	RPS6KA2	DUSP3	
SLC-MEDIATED TRANSMEMBRANE TRANSPORT%REACTOME DATABASE ID RELEASE 74%425407	SLC-mediated transmembrane transport	SLC34A1	SLC9A2	SLC9A3	SLC9A4	SLC5A8	SLC9A5	SLC9A6	SLC9A7	SLC9A8	SLC9A9	SLC26A2	SLC26A1	SLC1A1	SLC1A2	SLC1A4	SLC1A5	SLC1A6	SLC1A7	SLC9A1	SLC5A5	SLC15A3	SLC38A3	SLC15A4	SLC38A2	SLC38A5	SLC38A4	SLC4A10	SLC16A10	SLC26A7	SLC26A9	SLC26A4	SLC26A3	SLC26A6	SLC7A11	SLC7A10	SLC36A1	SLC36A2	SLC32A1	SLC7A5	SLC25A18	SLC7A6	SLC7A7	SLC7A8	SLC25A10	SLC24A2	SLC24A1	SLC24A4	SLC24A3	SLC20A2	SLC43A2	SLC20A1	SLC43A1	SLC25A5	SLC25A4	SLC5A12	SLC25A6	SLC3A2	SLC7A1	SLC7A3	SLC25A26	SLC25A29	SLC17A6	SLC17A7	SLC17A8	SLC17A1	SLC25A22	SLC36A4	CTNS	SLC8B1	SLC4A7	SLC8A3	SLC4A8	SLC4A9	SLC24A5	SLC30A7	SLC30A6	SLC30A8	SLC30A5	SLC2A4	SRI	SLC39A4	SLC5A2	SLC2A10	SLC16A1	RHAG	SLC22A12	SLC2A9	SLC2A8	SLC5A9	SLC30A10	SLC5A4	EMB	SLC2A14	SLC2A11	SLC2A12	SLC39A10	SLC39A14	SLC39A6	SLC16A7	SLC6A19	SLC39A5	SLC6A18	SLC39A8	SLC22A2	SLC39A7	SLC6A15	SLC39A2	SLC22A1	SLC39A1	SLC6A14	SLC39A3	SLC6A13	SLC14A1	SLC6A12	SLC14A2	SLC6A11	SLC6A1	SLC6A2	SLC13A1	SLC6A3	SLC13A2	SLC6A5	SLC16A8	SLC13A3	SLC6A6	SLC16A3	SLC13A4	SLC6A7	SLC6A9	SLC47A2	SLC18A1	SLC47A1	SLC18A2	SLC5A10	LCN9	SLC27A1	LCN15	LCN12	LCN1	SLC13A5	SLC27A6	APOD	SLC27A4	SLC35B3	SLC35B2	SLC35B4	SLC35D1	SLC45A3	SLC35D2	SLCO1B1	SLC10A6	PDZD11	KIAA1919	SLCO2B1	SLCO1B3	SLC31A1	SLC16A2	SLC30A3	SLC35A2	SLC30A2	SLC35A1	SLC35A3	SLC33A1	SLC30A1	SLC35C1	SLC41A2	SLC41A1	SLCO1C1	SLC5A6	ARL2BP	SLCO4A1	SLC2A6	SLCO4C1	SLC2A7	SLCO1A2	SLC34A2	SLCO2A1	SLC29A4	AVP	SLC7A9	SLC29A1	SLC50A1	SLC28A2	SLC3A1	SLC28A1	SLC29A3	SLC28A3	SLC29A2	SLC11A1	SLC40A1	HEPH	SLC44A5	SLC17A5	SLC44A3	SLC44A4	SLC44A1	SLC44A2	SLC11A2	RSC1A1	CP	SLC5A1	ARL2	SLC22A18	SLC6A20	SLC12A2	SLC12A3	SLC12A4	SLC12A5	SLC12A1	SLC12A6	SLC12A7	SLC2A2	BSG	SLC5A7	SLC22A5	SLC2A1	FGF21	SLC2A3	SLC1A3	ALB	RHCG	RHBG	RUNX1	SLC2A13	SLC5A11	SLC5A3	SLC22A4	SLC22A3	SLC22A6	SLC22A15	SLC22A16	SLC22A8	AHCYL2	SLC22A7	SLC4A1	SLC22A11	SLC4A2	SLC4A3	SLC4A4	SLC4A5	SLC8A1	SLC8A2	SLC26A11	SLC34A3	SLC38A1	SLC15A1	SLC15A2	
INHIBITION OF PKR%REACTOME%R-HSA-169131.4	Inhibition of PKR	EIF2AK2	
VITAMIN D (CALCIFEROL) METABOLISM%REACTOME%R-HSA-196791.6	Vitamin D (calciferol) metabolism	VDR	GC	CYP27B1	UBE2I	LGMN	SUMO2	PIAS4	CUBN	LRP2	CYP2R1	CYP24A1	
ALKBH2 MEDIATED REVERSAL OF ALKYLATION DAMAGE%REACTOME DATABASE ID RELEASE 74%112122	ALKBH2 mediated reversal of alkylation damage	ALKBH2	
SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24-HYDROXYCHOLESTEROL%REACTOME%R-HSA-193775.1	Synthesis of bile acids and bile salts via 24-hydroxycholesterol	AMACR	PTGIS	SLC27A2	AKR1C1	AKR1C4	AKR1C3	CYP46A1	SLC27A5	CYP8B1	CYP39A1	CYP27A1	HSD3B7	AKR1D1	AKR1C2	
ORGANELLE BIOGENESIS AND MAINTENANCE%REACTOME%R-HSA-1852241.5	Organelle biogenesis and maintenance	CSNK1E	DYNLL1	TUBG1	CKAP5	TUBA4A	HAUS2	HAUS1	AKAP9	CEP63	MAPRE1	SFI1	PAFAH1B1	PPARGC1A	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	KIF3B	HAUS8	HAUS7	PRKAR2B	KIF3C	CCT3	CEP70	BBS2	CEP72	BBS1	GLUD1	CEP192	GLUD2	CCT2	SIRT3	MKKS	TBL1X	PCNT	ARL6	CEP76	BBIP1	SSTR3	CLASP1	CEP78	MCHR1	PLK4	LZTFL1	DYNC1H1	TTC8	BBS10	ODF2	BBS12	CEP152	ARF4	TCP1	NDE1	PLK1	BBS9	BBS7	TUBB4B	CCT8	TUBB4A	BBS5	NEDD1	BBS4	CENPJ	CCT5	CDK1	CCT4	FGFR1OP	CEP41	PPARA	C2CD3	MEF2D	TCTN3	TCTN2	CRTC2	TCTN1	CRTC3	CEP97	CRTC1	MTERF1	CC2D2A	GABPA	DYNLL2	IQCB1	SIRT4	KIF24	TBL1XR1	SIRT5	SEPT2	PPRC1	TMEM216	FBF1	POLG2	TTBK2	PERM1	TMEM67	C10orf2	NPHP1	SSBP1	NPHP4	MARK4	SCLT1	AHI1	CEP162	CEP83	B9D1	CEP89	EXOC8	EXOC7	RAB3IP	ASAP1	PKD2	PKD1	RAB11A	RHO	EXOC4	CNGA2	EXOC3	EXOC6	CYCS	CNGA4	EXOC5	RAB11FIP3	EXOC2	EXOC1	CNGB1	GBF1	TRIP11	TFB1M	TFAM	TFB2M	POLRMT	TNPO1	ATP5S	ATP5A1	ATP5C1	ATP5J	ATP5I	MAPK14	ATP5H	MAPK11	ATP5G3	ATP5G2	ATP5O	ATP5G1	ATP5L	MT-ATP6	APOO	NCOA1	ATP5B	NCOA2	SAMM50	CHCHD3	NCOA6	MINOS1	ATP5E	CHCHD6	ATP5D	HSPA9	APOOL	MTX1	C19orf70	MTX2	RXRA	DNAJC11	IMMT	ATP5F1	MT-ATP8	ATP5J2	TMEM11	HDAC6	IFT172	DYNC2H1	RPGRIP1L	IFT88	SMO	KIF3A	TTC21B	IFT122	MKS1	IFT52	CHD9	IFT57	CREBBP	IFT140	WDR35	TRAF3IP1	IFT80	IFT81	DYNC2LI1	WDR60	HSPB11	CREB1	WDR34	ATAT1	WDR19	TTC30B	TTC30A	TCTEX1D1	TCTEX1D2	TGS1	IFT20	NR1D1	IFT22	IFT27	KIF17	DYNLRB2	DYNLRB1	TTC26	TCTE3	IFT43	SOD2	IFT46	IFT74	CLUAP1	CARM1	CAMK4	IDH2	B9D2	MED1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	PRKAB2	PRKAB1	NCOR1	NRF1	ALAS1	ESRRA	PDE6D	MAPK12	HCFC1	ACSS2	SMARCD3	HDAC3	ATF2	CEP57	YWHAE	CETN2	MEF2C	CEP164	CCP110	ARL13B	INPP5E	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	NINL	CEP290	YWHAG	RAB8A	CDK5RAP2	HELZ2	UNC119B	OFD1	HSP90AA1	RP2	ARL3	KIFAP3	NPHP3	CEP135	NPHP3-ACAD11	CYS1	TUBB	CEP131	HAUS4	PPARGC1B	HAUS3	CSNK1D	HAUS6	HAUS5	
GLUTATHIONE CONJUGATION%REACTOME%R-HSA-156590.2	Glutathione conjugation	GSTP1	GSTK1	GSTO1	GGT1	GGT5	CHAC2	GSTT2B	GSTM4	GSTM3	GSTM2	GSTM1	GSTO2	GSTM5	HPGDS	CHAC1	AKR1A1	GGT7	GSTA5	GGT6	GSTA4	GSTZ1	GSTA3	MGST3	GSTA2	MGST1	GSTA1	MGST2	CNDP2	GSTT2	GSTT1	ESD	GGCT	GCLC	GCLM	OPLAH	GSS	
MPS IIIA - SANFILIPPO SYNDROME A%REACTOME%R-HSA-2206307.2	MPS IIIA - Sanfilippo syndrome A	SGSH	
RHO GTPASES ACTIVATE PKNS%REACTOME%R-HSA-5625740.1	RHO GTPases activate PKNs	HIST2H2AC	PPP1R12B	H2AFJ	H2AFZ	H2AFX	H2AFV	CDC25C	HIST2H2BE	YWHAB	HIST4H4	HIST1H2BN	YWHAZ	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	KLK3	HIST1H2BL	KDM4C	PKN1	HIST1H2BK	HIST2H4A	HIST2H4B	RAC1	NCOA2	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	PKN3	PKN2	HIST2H3A	RHOC	HIST1H2BF	RHOA	HIST1H2BE	HIST1H2BH	MYL12B	PPP1R14A	RHOB	HIST1H2BG	HIST2H3D	MYL6	HIST1H2BB	HIST2H3C	MYH9	HIST1H2BA	MYH14	PDPK1	HIST1H2BD	MYH11	HIST1H2BC	MYH10	MYL9	H2AFB1	HIST1H3J	HIST1H3A	YWHAE	YWHAQ	HIST1H3F	HIST1H3G	PPP1CB	SFN	HIST1H3H	YWHAH	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	YWHAG	AR	H3F3A	KDM1A	H2BFS	HIST1H4A	PPP1R12A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	PAK1	HIST1H4F	HIST2H2AA3	HIST2H2AA4	KLK2	
CELL-EXTRACELLULAR MATRIX INTERACTIONS%REACTOME DATABASE ID RELEASE 74%446353	Cell-extracellular matrix interactions	PXN	ILK	FLNA	ARHGEF6	ITGB1	VASP	TESK1	ACTN1	PARVB	FBLIM1	RSU1	FLNC	LIMS1	LIMS2	FERMT2	
ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS%REACTOME DATABASE ID RELEASE 74%9687136	Aberrant regulation of mitotic exit in cancer due to RB1 defects	FZR1	UBE2C	UBE2D1	CDC23	UBE2S	CDC26	CDC16	CDC27	SKP2	ANAPC7	UBE2E1	RB1	ANAPC4	ANAPC5	ANAPC1	ANAPC2	ANAPC15	ANAPC16	ANAPC10	ANAPC11	
UBIQUINOL BIOSYNTHESIS%REACTOME%R-HSA-2142789.1	Ubiquinol biosynthesis	PDSS2	COQ9	PDSS1	COQ7	COQ6	COQ5	COQ3	COQ2	
CAM-PDE 1 ACTIVATION%REACTOME%R-HSA-111957.1	Cam-PDE 1 activation	PDE1C	PDE1B	PDE1A	
TNFR1-INDUCED NFKAPPAB SIGNALING PATHWAY%REACTOME DATABASE ID RELEASE 74%5357956	TNFR1-induced NFkappaB signaling pathway	TRAF2	SHARPIN	RIPK1	GNB2L1	CYLD	TNFAIP3	BIRC2	OTUD7B	BIRC3	TAB3	TAB2	TAB1	TRAF1	TNFRSF1A	RNF31	TNF	IKBKB	USP21	XIAP	USP4	USP2	IKBKG	MAP3K7	CHUK	TRADD	RBCK1	
LIPID PARTICLE ORGANIZATION%REACTOME%R-HSA-8964572.1	Lipid particle organization	CIDEA	HSD17B13	CIDEC	HILPDA	FITM1	FITM2	
TRANSCRIPTION FROM MITOCHONDRIAL PROMOTERS%REACTOME DATABASE ID RELEASE 74%75944	Transcription from mitochondrial promoters	TFAM	TFB2M	POLRMT	MTERF1	
CELLULAR SENESCENCE%REACTOME%R-HSA-2559583.4	Cellular Senescence	LMNB1	HIST2H2AC	FOS	H2AFJ	UBE2D1	CDC23	CDC26	CDC27	UBA52	ANAPC7	H2AFZ	UBE2E1	H2AFX	H2AFV	CCNA2	CCNA1	HIST2H2BE	CCNE2	CCNE1	HIST4H4	ANAPC4	ANAPC5	EZH2	ANAPC1	UBB	HIST1H2BN	HIST1H2BM	ANAPC2	ANAPC15	HIST1H2BO	ANAPC16	RING1	UBC	HIST1H2BJ	ANAPC10	HIST1H2BI	MAPK9	ANAPC11	HIST1H2BL	MAPK8	MAPK7	RPS27A	NBN	HIST1H2BK	FZR1	SUZ12	MAPK10	HIST2H4A	HIST2H4B	MAPK1	UBE2C	UBE2S	CDC16	MRE11A	CDK2	HIST3H3	RAD50	CEBPB	EHMT1	CXCL8	IL6	ASF1A	MAPKAPK5	E2F1	UBN1	SP1	MAP3K5	ERF	TNIK	RELA	MAPKAPK2	HMGA1	E2F2	NFKB1	MINK1	HIRA	MAPK14	MAP4K4	MAPK11	ETS1	ETS2	EP400	HMGA2	CABIN1	KDM6B	E2F3	BMI1	CDK4	RNF2	EED	TP53	PHC2	PHC1	TNRC6C	MOV10	AGO3	PHC3	AGO4	AGO1	TNRC6A	TNRC6B	IGFBP7	H1F0	VENTX	CDKN2D	CDKN2B	CDKN2C	HIST1H1D	HIST1H1E	HIST1H1A	HIST1H1B	HIST1H1C	IFNB1	ATM	CDK6	CDKN2A	STAT3	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	CDKN1A	CDKN1B	MDM2	MDM4	TXN	RB1	IL1A	TFDP1	TFDP2	HIST1H2AE	CBX8	HIST1H2AD	CBX6	HIST3H2BB	CBX4	HIST1H2AC	CBX2	HIST1H2AB	HIST1H2AJ	TINF2	TERF1	TERF2	POT1	HIST2H3A	TERF2IP	ACD	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	EHMT2	H2AFB1	HIST1H3J	HIST1H3A	MAP2K3	RBBP4	MAP2K4	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	RBBP7	HIST1H3B	HIST1H3C	MAPKAPK3	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	MAP2K7	MAP2K6	JUN	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	ID1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
HIV LIFE CYCLE%REACTOME DATABASE ID RELEASE 74%162587	HIV Life Cycle	VPS37C	VPS37D	VPS37A	VPS37B	NUP62	CHMP2B	CHMP2A	CHMP4C	NDC1	CHMP4B	SEC13	NUP133	UBAP1	UBA52	CHMP3	CHMP4A	RANGAP1	CHMP6	CHMP7	VPS28	NUP50	CHMP5	NUP54	CTDP1	UBB	ELL	CCNT1	SUPT4H1	TCEB3	UBC	TCEB2	CXCR4	TCEB1	NELFA	NELFCD	TCEB3C	RPS27A	TCEB3CL	TCEB3B	NELFE	SUPT16H	SSRP1	SUPT5H	CDK9	NUP43	RAE1	TCEA1	TCEB3CL2	RANBP2	NUP35	NUPL2	NUP37	CCNK	PPIA	NEDD4L	POLR2A	POLR2B	POLR2C	NCBP1	POLR2D	NCBP2	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	FEN1	POLR2K	POLR2L	CCNT2	LIG1	GTF2A1	GTF2A2	GTF2B	TAF9	TAF1L	AK6	GTF2E1	GTF2E2	TAF7L	TAF9B	TAF15	TAF12	TAF13	TAF10	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	RCC1	NMT1	XPO1	NMT2	PDCD6IP	RNMT	RANBP1	XRCC6	RNGTT	XRCC5	HMGA1	PSIP1	KPNA1	TBP	GTF2F1	GTF2F2	XRCC4	CCR5	LIG4	RAN	NUP107	NUP188	BANF1	FURIN	NUP214	NUP210	CD4	NUP93	NELFB	NUP205	CCNH	POM121	AAAS	NUP160	NUP85	TPR	NUP88	GTF2H1	NUP155	GTF2H2	GTF2H3	GTF2H4	GTF2H5	CDK7	NUP153	ERCC3	ERCC2	TSG101	MNAT1	VPS4B	VPS4A	MVB12B	MVB12A	VTA1	
TAT-MEDIATED ELONGATION OF THE HIV-1 TRANSCRIPT%REACTOME%R-HSA-167246.2	Tat-mediated elongation of the HIV-1 transcript	NELFB	CTDP1	CCNH	ELL	CCNT1	SUPT4H1	POLR2A	TCEB3	POLR2B	TCEB2	POLR2C	TCEB1	NELFA	POLR2D	NELFCD	NCBP1	TCEB3C	NCBP2	POLR2E	TCEB3CL	POLR2F	TCEB3B	NELFE	GTF2F1	POLR2G	SUPT16H	GTF2F2	POLR2H	SSRP1	POLR2I	SUPT5H	POLR2J	CDK9	TCEA1	POLR2K	TCEB3CL2	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	CDK7	ERCC3	ERCC2	MNAT1	
AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS%REACTOME DATABASE ID RELEASE 74%198693	AKT phosphorylates targets in the nucleus	FOXO6	NR4A1	FOXO4	RPS6KB2	AKT1	CREB1	FOXO3	FOXO1	AKT2	AKT3	
TWIK RELATED POTASSIUM CHANNEL (TREK)%REACTOME DATABASE ID RELEASE 74%1299503	TWIK related potassium channel (TREK)	KCNK4	KCNK10	KCNK2	
INTERLEUKIN-27 SIGNALING%REACTOME%R-HSA-9020956.1	Interleukin-27 signaling	IL27RA	IL27	IL6ST	JAK2	JAK1	EBI3	TYK2	STAT1	CRLF1	STAT3	CANX	
FRUCTOSE BIOSYNTHESIS%REACTOME%R-HSA-5652227.3	Fructose biosynthesis	SORD	AKR1B1	
DEFECTIVE SLC36A2 CAUSES IMINOGLYCINURIA (IG) AND HYPERGLYCINURIA (HG)%REACTOME DATABASE ID RELEASE 74%5619041	Defective SLC36A2 causes iminoglycinuria (IG) and hyperglycinuria (HG)	SLC36A2	
SIGNALING BY RECEPTOR TYROSINE KINASES%REACTOME DATABASE ID RELEASE 74%9006934	Signaling by Receptor Tyrosine Kinases	SH3KBP1	RALA	RALB	ASCL1	KIDINS220	RIT1	RIT2	FOSB	PTPRU	SOCS6	CDK5R2	FER	GRAP	UBA52	UBB	SPARC	UBC	RPS27A	FGFBP1	STAT5A	FGFBP2	STAT5B	FGFBP3	IRS2	PIK3CB	CDK5R1	PTK6	VAV1	CRKL	MST1R	RAPGEF1	JAK2	USP8	RNF41	FES	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	SGK1	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	EPN1	YWHAB	CTNND1	HSPB1	PRKCD	MAPKAPK2	CDH5	CYFIP2	NCKAP1	CYFIP1	MAPK14	MAPK11	CUL5	IGF2	IGF1	BRK1	NCK1	VAV3	VAV2	ELMO1	ELMO2	NCKAP1L	WASF1	WASF2	PTPRS	IRS1	WASF3	SRC	NTRK3	PTPRO	NTF3	BAX	NELFB	BAIAP2	ABI2	ABI1	NCF1	NCF2	NCF4	PLAT	NOS3	THBS4	PRKACG	CYBB	THBS3	PRKACB	PDGFD	FGFRL1	FLT3LG	FRS2	FRS3	EREG	BTC	PIK3R4	PDGFB	TGFA	PSEN2	NEDD4	RALGDS	APH1A	BRAF	APH1B	GRIN2B	PTK2	EP300	PSENEN	AREG	STAM	CREB1	HGS	DUSP4	ITCH	ITGA3	GAB2	STAM2	DUSP6	DUSP7	PTPN12	KIT	TLR9	HBEGF	RANBP9	EPGN	MUC20	KLB	STMN1	RBFOX2	FGF1	CILP	FGF2	SHB	FGF3	IRS4	FGF4	TIA1	FGF6	ADAP1	FGF7	GFAP	ESRP2	FGF9	CSN2	TIAL1	SH2D2A	AXL	PDGFRB	PDGFRA	MXD4	MAP2K1	MAP2K2	HGF	SHC2	SHC3	RAP1B	RAP1A	FGF20	FGF23	FGF22	ESRP1	FGF16	STUB1	FGF19	FGF18	FGFR4	GALNT3	FLRT2	FGF10	FLRT1	GRAP2	FLT3	ITGB3	NCBP1	NCBP2	PDE3B	SPRED2	SPRED1	GABRG3	GABRG2	PPP2R5D	NRG1	GABRB3	NRG2	GABRB2	GABRB1	NRG3	NRG4	RASA1	PIK3C3	MET	PAG1	STAT6	CSK	GABRQ	GABRA1	PTPN11	CHEK1	MAPK12	PRKCZ	EPS15	SH3GL1	PTPN3	GTF2F1	GTF2F2	AHCYL1	CLTC	CLTA	YES1	PPP2R1B	PRKCB	PRKCA	PTK2B	INS	PTPN18	PTPN2	ATF1	CHD4	ATF2	ELK1	MEF2A	THBS2	PXN	MEF2C	VRK3	MAPKAPK3	SOCS1	TEC	DUSP3	FOS	DNM1	DNM2	DNM3	JUP	SPHK1	MAPK7	S100B	PPP2CA	PPP2CB	NGF	MAPK1	ERBB2IP	CTNNA1	WWOX	MEF2D	NAB1	NAB2	CXCL12	ADCYAP1	NCK2	ADCYAP1R1	ITGAV	ITGA2	MEMO1	DIAPH1	LAMC3	LAMA4	LAMB2	BDNF	LYN	TAB2	EGR2	NRP1	NRP2	ESR1	ARHGEF7	YAP1	PTPN6	PRR5	ITGB1	PDPK1	MAPKAP1	SH3GL2	NTRK1	PIK3R3	ADORA2A	PIK3R2	PIK3R1	MTOR	PIK3CA	LCK	AKT2	AKT3	MLST8	THEM4	AKT1	TRIB3	FYN	CAV1	RICTOR	DLG4	ITPR1	TCIRG1	ITPR2	ITPR3	ATP6V1E1	ATP6V1E2	JUNB	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	ATP6AP1	ATP6V1B2	ATP6V0D1	PAK1	RPS6KA5	ATP6V0D2	ATP6V0C	PAK3	ATP6V1B1	PAK2	ATP6V1A	LAMA2	AAMP	LAMA1	ATP6V0A2	ATP6V1H	ATP6V0A4	ATP6V1G3	ATP6V0E2	ATP6V1D	ATP6V1C1	ATP6V1C2	ATP6V0A1	CDK5	CTNNB1	ATP6V1F	MAPK13	DOCK3	INSR	SRF	DOCK7	NTF4	RAC1	WWP1	HNRNPM	HNRNPF	DOCK1	CDC42	SH2B3	HNRNPH1	FLRT3	ROCK1	ROCK2	COL4A2	COL4A1	RHOA	COL6A2	COL4A4	PGR	GRB7	COL4A3	ERBB2	COL6A1	COL6A3	MKNK1	COL4A5	SPRY2	TCF12	PTPN1	COL6A6	COL6A5	CRK	NCOR1	BCAR1	NTRK2	STAT1	STAT3	ADAM10	PTBP1	ADAM17	GRB10	RPS6KA3	PSEN1	RPS6KA2	RPS6KA1	MAPK3	PRKCE	NCSTN	PTPRJ	SPINT2	TNS4	TNS3	HGFAC	SPINT1	HNRNPA1	HPN	COL9A1	COL9A3	LRIG1	RAB4B	COL9A2	RANBP10	SHC1	LAMC2	EGF	GAB1	LAMC1	CBL	EGFR	NRAS	CDC37	PLCG1	SOS1	HRAS	AP2A1	PCSK6	FIGF	AP2A2	FLT1	FLT4	PCSK5	VEGFB	KDR	VEGFC	PGF	AP2M1	VEGFA	ANOS1	MMP9	EPS15L1	LAMA5	LAMA3	PLG	FURIN	ARF6	SPP1	AP2S1	LAMB3	CMA1	APOE	LAMB1	GGA3	MATK	CYBA	AP2B1	THBS1	IGF1R	REST	RAB4A	TIAM1	PPP2R1A	PRKACA	SH3GL3	ARC	TRIB1	TPH1	RRAD	F3	MAP2K5	HSP90AA1	EGR1	JUND	EGR3	EGR4	FOSL1	ID2	ID1	ADAM12	ID4	ID3	DNAL4	PTPRK	LYL1	VGF	SPRY1	
GLUCOSE METABOLISM%REACTOME DATABASE ID RELEASE 74%70326	Glucose metabolism	NUP62	NDC1	SEC13	NUP133	NUP50	PGM2L1	NUP54	MDH2	PPP2CA	PPP2CB	PCK1	NUP43	RAE1	RANBP2	SLC25A10	NUP35	NUPL2	NUP37	GPI	ADPGK	NUP107	ENO1	NUP188	ENO2	ENO3	HK2	HK1	HK3	PPP2R1B	TPI1	PGAM1	PGAM2	BPGM	GAPDHS	PGP	ALDOC	NUP214	ALDOB	NUP210	ALDOA	GAPDH	PFKFB2	PFKFB1	PFKFB4	PFKFB3	PGK1	GOT1	NUP93	PGK2	GOT2	PFKL	GNPDA1	GNPDA2	PFKM	PFKP	NUP205	POM121	AAAS	G6PC	NUP160	PRKACG	PRKACB	NUP85	TPR	SLC25A1	NUP88	G6PC3	PPP2R1A	PCK2	PRKACA	GCKR	MDH1	NUP155	GCK	PC	PPP2R5D	SLC37A1	NUP153	G6PC2	SLC25A12	SLC25A11	FBP1	FBP2	SLC25A13	
INTERLEUKIN-4 AND INTERLEUKIN-13 SIGNALING%REACTOME%R-HSA-6785807.6	Interleukin-4 and Interleukin-13 signaling	FCER2	FOS	JAK3	ICAM1	GATA3	FOXO1	JAK1	ITGAX	HMOX1	BIRC5	VCAM1	NANOG	LCN2	MUC1	MYC	SAA1	FOXO3	FGF2	MAOA	VIM	JAK2	HGF	CXCL8	PTGS2	CCL2	RORC	COL1A2	RORA	TNFRSF1B	IRF4	BCL2L1	IL10	IL6	BCL2	ANXA1	STAT1	STAT3	TNF	ZEB1	CCL11	CCL22	HIF1A	ALOX15	IL2RG	STAT6	PIM1	IL13RA2	CDKN1A	IL13RA1	BCL6	FSCN1	NDN	MCL1	SOCS5	IGHE	IL23R	IL12B	IL12A	IL23A	LIF	TIMP1	POU2F1	MMP1	MMP2	VEGFA	MMP3	TWIST1	HSPA8	MMP9	OPRD1	IL18	OSM	IL1A	BATF	IL1B	LAMA5	IL17F	IL17A	IL4R	CEBPD	FASLG	IL4	OPRM1	IL13	TYK2	SOCS3	TGFB1	SOX2	ITGB1	IGHG4	IL6R	IGHG1	FN1	S1PR1	PIK3R1	NOS2	F13A1	AKT1	POMC	HSP90B1	CCND1	SOCS1	RHOU	JUNB	HSP90AA1	ITGAM	ITGB2	LBP	CD36	TP53	ALOX5	
RUNX2 REGULATES CHONDROCYTE MATURATION%REACTOME DATABASE ID RELEASE 74%8941284	RUNX2 regulates chondrocyte maturation	IHH	CBFB	GLI2	HDAC4	
SYNTHESIS OF GDP-MANNOSE%REACTOME%R-HSA-446205.1	Synthesis of GDP-mannose	PMM2	MPI	GMPPB	PMM1	GMPPA	
ESTABLISHMENT OF SISTER CHROMATID COHESION%REACTOME DATABASE ID RELEASE 74%2468052	Establishment of Sister Chromatid Cohesion	STAG1	STAG2	SMC3	CDCA5	WAPAL	PDS5B	PDS5A	ESCO1	ESCO2	SMC1A	RAD21	
COX REACTIONS%REACTOME%R-HSA-140180.1	COX reactions	PTGS1	
PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION%REACTOME%R-HSA-9660826.1	Purinergic signaling in leishmaniasis infection	ENTPD5	NFKB1	NT5E	TXNIP	P2RX7	TXN	MEFV	P2RX4	SUGT1	PYCARD	HSP90AB1	IL18	C3	NFKB2	RELA	NLRP3	IL1A	IL1B	PSTPIP1	CASP1	C3AR1	CTSG	ENTPD1	
DEFECTIVE SLCO1B3 CAUSES HYPERBILIRUBINEMIA, ROTOR TYPE (HBLRR)%REACTOME DATABASE ID RELEASE 74%5619058	Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR)	SLCO1B3	
PAUSING AND RECOVERY OF TAT-MEDIATED HIV ELONGATION%REACTOME%R-HSA-167238.2	Pausing and recovery of Tat-mediated HIV elongation	NELFB	CTDP1	ELL	CCNT1	SUPT4H1	POLR2A	TCEB3	POLR2B	TCEB2	POLR2C	TCEB1	NELFA	POLR2D	NELFCD	TCEB3C	POLR2E	TCEB3CL	POLR2F	TCEB3B	NELFE	GTF2F1	POLR2G	SUPT16H	GTF2F2	POLR2H	SSRP1	POLR2I	SUPT5H	POLR2J	CDK9	TCEA1	POLR2K	TCEB3CL2	POLR2L	
INSULIN PROCESSING%REACTOME%R-HSA-264876.2	Insulin processing	PCSK2	MYO5A	ERO1LB	KIF5C	SLC30A7	INS	SLC30A6	SLC30A8	ERO1L	SLC30A5	MYRIP	TMEM27	CPE	STX1A	EXOC8	EXOC7	EXOC4	EXOC3	EXOC6	KIF5B	EXOC5	KIF5A	RAB27A	EXOC2	EXOC1	VAMP2	PCSK1	
TOXICITY OF TETANUS TOXIN (TENT)%REACTOME DATABASE ID RELEASE 74%5250982	Toxicity of tetanus toxin (TeNT)	VAMP2	
TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX%REACTOME DATABASE ID RELEASE 74%445989	TAK1 activates NFkB by phosphorylation and activation of IKKs complex	RIPK2	TRAF6	UBE2V1	RELA	UBE2N	TAB3	TAB2	APP	NOD1	TAB1	NOD2	IRAK2	NFKB1	S100B	NFKBIA	SAA1	AGER	NFKBIB	IRAK1	S100A12	IKBKB	NFKB2	HMGB1	NKIRAS1	NKIRAS2	IKBKG	MAP3K7	CHUK	
DEFECTIVE SLC12A3 CAUSES GITELMAN SYNDROME (GS)%REACTOME%R-HSA-5619087.1	Defective SLC12A3 causes Gitelman syndrome (GS)	SLC12A3	
UB-SPECIFIC PROCESSING PROTEASES%REACTOME DATABASE ID RELEASE 74%5689880	Ub-specific processing proteases	IFIH1	HIST2H2AC	CFTR	SKP2	UBA52	CCNA2	CCNA1	HIST2H2BE	CYLD	BIRC2	BIRC3	VDAC3	VDAC2	UBB	HIST1H2BN	VDAC1	HIST1H2BM	HIST1H2BO	UBC	HIST1H2BJ	HIST1H2BI	HIST1H2BL	RPS27A	USP11	HIST1H2BK	USP9X	USP21	USP8	SMAD4	CDC20	USP33	DDB2	USP7	FOXO4	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	HIF1A	PSMD1	TAF9B	AXIN1	IKBKG	MAP3K7	PSMA5	TAF10	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	USP30	PSME2	MAT2B	PTEN	PSMD10	TRAF6	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	TAB1	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	NFKBIA	PSMC5	USP10	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	TOMM20	TRAF2	RIPK1	SMAD2	SMAD3	TGFBR1	BECN1	IDE	USP13	RNF146	UFD1L	RCE1	TP53	GATA3	HGS	TOMM70A	STAM2	CLSPN	USP17L2	MYC	HIST2H2AB	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	TNKS2	HIST1H2AI	TNKS	HIST1H2AH	HIST1H2AK	HIST2H2BF	HIST3H2A	IL33	USP15	SMURF2	SMAD7	DDX58	USP18	PTRH2	ARRB1	ARRB2	MUL1	ATXN7	KEAP1	POLB	SNX3	OTUB1	RUVBL1	CDC25A	MDM2	MDM4	USP17L4	USP17L5	USP17L8	RNF128	TADA2B	WDR48	ADRB2	ADRM1	WDR20	USP17L3	USP17L1	TRRAP	USP5	USP3	FKBP8	TADA3	HIST1H2AE	HIST1H2AD	SMAD1	HIST3H2BB	HIST1H2AC	HIST1H2AB	USP34	HIST1H2AJ	AXIN2	USP17L30	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	USP17L27	HIST1H2BB	RHOT1	USP17L26	USP17L29	HIST1H2BA	USP17L28	USP17L21	HIST1H2BD	USP17L20	HIST1H2BC	USP17L22	USP17L25	USP17L24	SUDS3	USP17L15	USP17L18	USP17L17	USP17L19	USP17L10	USP17L12	USP17L11	USP17L13	CCP110	RNF123	USP37	USP47	USP48	USP49	USP42	USP44	USP14	AR	USP16	KAT2A	USP12	USP19	USP24	USP25	USP26	SIAH2	USP4	USP2	USP20	USP22	USP28	HIST2H2AA3	HIST2H2AA4	
ABC TRANSPORTERS IN LIPID HOMEOSTASIS%REACTOME%R-HSA-1369062.2	ABC transporters in lipid homeostasis	ABCD2	ABCD3	ABCA12	ABCG8	ABCG5	ABCD1	ABCA10	ABCG4	ABCG1	APOA1	PEX3	ABCA2	ABCA5	ABCA6	PEX19	ABCA3	ABCA9	ABCA7	
ACTIVATION, TRANSLOCATION AND OLIGOMERIZATION OF BAX%REACTOME%R-HSA-114294.2	Activation, translocation and oligomerization of BAX	BID	BAX	
RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION%REACTOME DATABASE ID RELEASE 74%8941332	RUNX2 regulates genes involved in cell migration	MMP13	AKT1	CBFB	ITGA5	ITGBL1	AKT2	AKT3	
DEFECTIVE ABCB4 CAUSES PFIC3, ICP3 AND GBD1%REACTOME DATABASE ID RELEASE 74%5678771	Defective ABCB4 causes PFIC3, ICP3 and GBD1	ABCB4	
TANDEM OF PORE DOMAIN IN A WEAK INWARDLY RECTIFYING K+ CHANNELS (TWIK)%REACTOME DATABASE ID RELEASE 74%1299308	Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	KCNK1	KCNK6	KCNK7	
MISMATCH REPAIR (MMR) DIRECTED BY MSH2:MSH3 (MUTSBETA)%REACTOME DATABASE ID RELEASE 74%5358606	Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	PMS2	PCNA	RPA1	MSH3	RPA2	LIG1	MLH1	POLD3	POLD4	RPA3	POLD1	MSH2	EXO1	POLD2	
ENERGY DEPENDENT REGULATION OF MTOR BY LKB1-AMPK%REACTOME DATABASE ID RELEASE 74%380972	Energy dependent regulation of mTOR by LKB1-AMPK	PRKAA1	PRKAA2	CAB39	CAB39L	PRKAG1	PRKAG2	PRKAG3	RPTOR	STK11	SLC38A9	PRKAB2	STRADA	STRADB	TSC2	TSC1	PRKAB1	MTOR	PPM1A	RRAGA	RRAGC	MLST8	RRAGB	RHEB	RRAGD	LAMTOR2	LAMTOR1	LAMTOR4	LAMTOR3	LAMTOR5	
EXTRA-NUCLEAR ESTROGEN SIGNALING%REACTOME%R-HSA-9009391.3	Extra-nuclear estrogen signaling	MAPK3	AREG	CDKN1B	FOS	CREB1	GNG12	GNG11	GNG13	PRKCZ	PRMT1	GNB2	EGF	GNB1	EGFR	GNB4	NRAS	GNB3	XPO1	GNB5	SPHK1	HRAS	GNAT3	HBEGF	MMP7	SRF	ZDHHC7	FOXO3	EPGN	UHMK1	MAPK1	MMP2	MMP3	MMP9	ZDHHC21	CAV2	ESR1	GNAI3	GNAI1	GNAI2	ESR2	STRN	SRC	IGF1R	PDPK1	S1PR3	PIK3R3	PIK3R2	PIK3R1	PIK3CA	NOS3	ELK1	AKT2	AKT3	GNGT1	AKT1	BCL2	GNGT2	CAV1	CCND1	EREG	BTC	TGFA	GNG3	GNG10	HSP90AA1	GNG2	GNG5	GNG4	GNG7	GNG8	PTK2	
RESISTANCE OF ERBB2 KD MUTANTS TO AEE788%REACTOME%R-HSA-9665250.1	Resistance of ERBB2 KD mutants to AEE788	ERBB2	HSP90AA1	CDC37	ERBB2IP	
DISEASES OF BASE EXCISION REPAIR%REACTOME DATABASE ID RELEASE 74%9605308	Diseases of Base Excision Repair	OGG1	NEIL1	NEIL3	NTHL1	
BETA DEFENSINS%REACTOME DATABASE ID RELEASE 74%1461957	Beta defensins	DEFB119	DEFB118	DEFB116	DEFB115	DEFB114	TLR1	DEFB105A	DEFB105B	DEFB113	DEFB112	DEFB110	DEFB1	DEFB106B	DEFB106A	TLR2	DEFB129	DEFB128	DEFB127	DEFB126	DEFB125	DEFB124	DEFB123	DEFB107A	DEFB121	DEFB107B	CCR6	CCR2	DEFB136	DEFB135	DEFB134	DEFB133	DEFB108B	DEFB132	DEFB131	DEFB103A	DEFB103B	DEFB4A	DEFB4B	DEFB104B	DEFB104A	
HYALURONAN METABOLISM%REACTOME DATABASE ID RELEASE 74%2142845	Hyaluronan metabolism	HEXB	CHP1	HEXA	HAS1	CEMIP	HYAL1	HAS3	ABCC5	HYAL3	HAS2	HMMR	LYVE1	SLC9A1	CD44	HYAL2	STAB2	GUSB	
ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES%REACTOME%R-HSA-8963889.2	Assembly of active LPL and LIPC lipase complexes	PCSK5	LIPC	CREB3L3	FGF21	GPIHBP1	MBTPS1	APOA4	APOA5	APOC2	ANGPTL3	MBTPS2	ANGPTL4	C19orf80	LPL	FURIN	LMF2	LMF1	PCSK6	
PYRIMIDINE CATABOLISM%REACTOME DATABASE ID RELEASE 74%73621	Pyrimidine catabolism	NT5E	AGXT2	DPYS	UPB1	NT5C1A	TYMP	NT5C	DPYD	UPP2	NT5M	UPP1	
G ALPHA (12 13) SIGNALLING EVENTS%REACTOME DATABASE ID RELEASE 74%416482	G alpha (12 13) signalling events	ARHGEF26	ABR	GNG12	GNG11	NGEF	ECT2	GNG13	ARHGEF33	ARHGEF35	ARHGEF37	ARHGEF39	ARHGEF38	GNB2	GNB1	NET1	GNB4	GNB3	ARHGEF10L	GNB5	SOS1	ADRA1D	AKAP13	MCF2L	ADRA1B	ARHGEF10	ADRA1A	PLEKHG2	TRIO	ARHGEF15	PLEKHG5	ARHGEF17	ARHGEF16	KALRN	ARHGEF19	ARHGEF18	ARHGEF9	ARHGEF3	ARHGEF4	ARHGEF1	ARHGEF2	ARHGEF5	ARHGEF6	VAV1	FGD1	FGD2	GNA13	FGD3	FGD4	VAV3	SOS2	MCF2	VAV2	BTK	TBXA2R	ARHGEF7	ARHGEF11	ARHGEF12	ROCK1	ROCK2	RHOC	RHOA	RHOB	GNA12	PLXNB1	RASGRF2	GNGT1	TIAM1	GNGT2	GNG3	GNG10	PREX1	GNG2	ARHGEF40	ITSN1	GNG5	GNG4	GNG7	GNG8	TIAM2	OBSCN	
PCP CE PATHWAY%REACTOME DATABASE ID RELEASE 74%4086400	PCP CE pathway	PSMA6	FZD2	PSMA3	FZD5	PSMA4	FZD7	PSMA1	FZD4	DAAM1	PSMA2	FZD6	PSME3	PSME4	PSME1	FZD8	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PRKCG	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	AP2A1	UBC	PSMB1	PSMF1	SHFM1	PSMB8	AP2A2	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	AP2M1	PSMC1	PSMC2	CLTC	CLTA	RAC1	PARD6A	AP2S1	WNT5B	PRKCB	ROR1	ROR2	PRKCA	RHOA	AP2B1	CLTB	SCRIB	SMURF2	PRICKLE1	SMURF1	DVL1	VANGL2	DVL2	DVL3	RAC2	PFN1	ARRB2	RAC3	WNT5A	PSMD8	PSMD9	PSMD6	PSMD7	WNT11	PSMD4	PSMD5	PSMD2	PSMD3	WNT1	PSMD1	WNT4	FZD1	FZD3	PSMA5	
SIGNALING BY PDGFR IN DISEASE%REACTOME DATABASE ID RELEASE 74%9671555	Signaling by PDGFR in disease	FIP1L1	KDR	ETV6	KANK1	STAT1	PIK3CB	GOLGA4	STAT3	NRAS	SOS1	HRAS	WDR48	PIK3R2	PDGFRA	PIK3R1	PIK3CA	STRN	
ANDROGEN BIOSYNTHESIS%REACTOME%R-HSA-193048.2	Androgen biosynthesis	LHB	POMC	HSD17B12	CGA	CYP17A1	HSD17B3	HSD3B2	SRD5A2	SRD5A3	HSD3B1	SRD5A1	
INOSITOL PHOSPHATE METABOLISM%REACTOME DATABASE ID RELEASE 74%1483249	Inositol phosphate metabolism	PTEN	IP6K2	INPP5B	PLCB4	PLCG1	PLD4	INPP5D	OCRL	MTMR9	IPPK	ISYNA1	INPP1	MTMR7	NUDT3	NUDT4	INPP4A	NUDT11	INPP4B	NUDT10	INPP5A	PLCB3	PPIP5K1	PLCB1	PLCZ1	PLCB2	IMPA1	PPIP5K2	INPP5J	IMPA2	ITPK1	PLCE1	IP6K1	IP6K3	MIOX	SYNJ1	IPMK	ITPKB	ITPKC	PLCG2	MINPP1	ITPKA	PLCH1	PLCH2	INPPL1	PLCD3	PLCD4	PLCD1	
HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS%REACTOME%R-HSA-629597.2	Highly calcium permeable nicotinic acetylcholine receptors	CHRNA5	CHRNA4	CHRNA6	CHRNA1	CHRNB2	CHRNA3	CHRNB4	CHRNB3	CHRNA2	
NUCLEOSOME ASSEMBLY%REACTOME%R-HSA-774815.1	Nucleosome assembly	HIST2H2AC	H2AFJ	RUVBL1	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HJURP	ITGB3BP	HIST4H4	SMARCA5	OIP5	CENPA	STRA13	CENPC	NPM1	RSF1	HIST1H2BN	CENPT	MIS18BP1	HIST1H2BM	CENPU	HIST1H2BO	CENPW	APITD1	HIST1H2BJ	MIS18A	CENPH	HIST1H2BI	CENPI	HIST1H2BL	CENPK	CENPL	HIST1H2BK	CENPM	CENPN	HIST2H4A	CENPO	HIST2H4B	CENPP	CENPQ	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	RBBP4	RBBP7	HIST1H4K	HIST1H4L	CASC5	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
LXRS REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS%REACTOME DATABASE ID RELEASE 74%9623433	LXRs regulate gene expression to control bile acid homeostasis	FABP6	RXRA	RXRB	NCOA1	UGT1A3	NR1H2	NCOR2	NR1H3	NCOR1	
SUPPRESSION OF AUTOPHAGY%REACTOME%R-HSA-9636569.1	Suppression of autophagy	DUSP16	RAB7A	
NONHOMOLOGOUS END-JOINING (NHEJ)%REACTOME%R-HSA-5693571.1	Nonhomologous End-Joining (NHEJ)	BABAM1	HERC2	DCLRE1C	UIMC1	RIF1	WHSC1	POLL	RNF168	NHEJ1	RNF8	POLM	BRCC3	TDP2	TDP1	TP53BP1	H2AFX	HIST2H2BE	BRE	FAM175A	HIST4H4	PIAS4	UBE2N	HIST1H2BN	HIST1H2BM	XRCC6	XRCC5	HIST1H2BO	PAXIP1	HIST1H2BJ	HIST1H2BI	BRCA1	HIST1H2BL	NBN	HIST1H2BK	HIST2H4A	HIST2H4B	XRCC4	MRE11A	HIST3H3	LIG4	RAD50	SUMO1	BARD1	HIST3H2BB	MDC1	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	ATM	HIST1H2BD	HIST1H2BC	UBE2V2	PRKDC	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	
INFECTIOUS DISEASE%REACTOME%R-HSA-5663205.11	Infectious disease	CBLL1	SH3KBP1	VCP	CXCR4	TBL1X	SUZ12	VAV1	PLCG2	JAK2	TBL1XR1	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	CTNND1	XPO1	CYFIP2	XRCC4	NCKAP1	CCR5	MAPK14	CYFIP1	WIPF1	LIG4	ARPC1B	CUL5	WIPF2	ARPC1A	WIPF3	BRK1	WASL	ACTB	ACTG1	NCK1	ACTR3	VAV3	ACTR2	VAV2	MYH2	ELMO1	BTK	ELMO2	WAS	NCKIPSD	NCKAP1L	WASF1	WASF2	WASF3	MYO10	MYO5A	ARPC4	MYO9B	ARPC5	BAIAP2	MYO1C	ABI2	ARPC2	ARPC3	ABI1	PRKACG	PRKACB	RBX1	ADCY9	PRKAR1B	PRKAR1A	PRKAR2A	PIK3R4	GNAS	TSG101	PTK2	VPS4B	VPS4A	MVB12B	MVB12A	ADCY4	VPS36	VTA1	ADCY3	VPS37C	ADCY2	VPS37D	ADCY1	VPS37A	ADCY8	VPS37B	ADCY7	ADCY6	STAM	SNF8	JAK3	ADCY5	JAK1	HGS	CHMP2B	CHMP2A	CHMP4C	CHMP4B	UBAP1	CHMP3	RANGAP1	CHMP4A	CHMP6	CHMP7	STAM2	VPS25	VPS28	CHMP5	HCK	TLR9	HBEGF	ENO1	MAP2K1	MAP2K2	PGK1	NEDD4L	PML	DUSP16	FEN1	LIG1	PIK3C3	MET	EPS15	SH3GL1	NPM1	EEF2	C3	IGHG4	IGHG1	IGHG2	ELK1	MAP2K4	MAP2K7	JUN	NFKB2	DYNC1LI1	DYNC1LI2	TLR7	TLR2	MAN2A1	MAPK8	ARF1	RNF213	DYNLL2	ACE2	TMPRSS2	GTF2A1	GTF2A2	GTF2B	TAF9	TAF1L	GSK3A	AK6	DYNC1I1	GTF2E1	GTF2E2	TAF7L	GALNT1	TAF9B	TAF15	TAF12	TAF13	TAF10	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	TRIM28	ADORA2A	GNGT1	GNGT2	WNT5A	ITPR1	ITPR2	ITPR3	GNG3	GNG10	KDM1A	GNG2	GNG5	GNG4	GNG7	GNG8	GNG12	GNG11	GNG13	PHF21A	ABL1	GNB2	GNB1	GNB4	GNB3	CTNNB1	GNB5	RAB5A	HMG20B	RAC1	DOCK2	DOCK1	HDAC2	HDAC1	CDC42	ROCK1	ROCK2	PPIA	MYH9	SYK	CRK	MAPK3	CBL	EGFR	PLCG1	RXFP1	RXFP2	GPR176	AP2A1	GNAT3	C3AR1	PTGDR	ENTPD1	ENTPD5	AP2A2	TXNIP	LHB	TXN	MEFV	CRHR2	MC2R	AP2M1	CGA	GPR15	MC1R	NOX1	GPR27	GPR25	GPR20	MC4R	GPR39	FSHB	GPR32	IL18	GPBAR1	MC3R	IL1A	IL1B	FSHR	NPSR1	PTGER4	GPR45	PTGER2	GNAI3	VAMP2	NOXO1	GNAI1	AP2S1	GNAI2	NPS	NT5E	GPR150	GPHA2	P2RY11	MC5R	GPHB5	PYCARD	CYSLTR1	GGT1	LHCGR	CYBA	DPEP2	AP2B1	DPEP1	DPEP3	GNAZ	GPR83	GPR84	DVL1	DVL2	NLRP3	DVL3	GGT5	NOXA1	RLN2	RLN3	PSTPIP1	CASP1	INSL3	TSHB	PTGIR	AVPR2	ADORA2B	TSHR	P2RX7	POMC	P2RX4	SUGT1	PRKACA	GUCY2C	BTRC	SH3GL3	SKP1	HSP90AA1	TUBB	DYNLL1	UBA52	DYNC1I2	UBB	PRKAR2B	UBC	RPS27A	DYNC1H1	CCNK	MAP1LC3B	RPL4	DAXX	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	IL10	RPL36AL	IL6	RPS18	RPL36	CD163	RPL35	PLK2	RPL38	RHBDF2	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	CCNT2	RPS7	SYT2	RPS8	SYT1	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	ST6GALNAC2	RPN2	RPL41	PRKCSH	RPL3L	TUSC3	RPN1	RPS26	RPS25	MAGT1	GANAB	RPS28	FUT8	MGAT5	RPS27	ST3GAL4	RPS29	RPL27A	MGAT1	MGAT2	RPS20	ST3GAL1	RPS21	ST3GAL2	RPS24	ST3GAL3	RPS23	RPLP1	ST6GAL1	EDEM2	RPLP0	MOGS	RPS4X	DDOST	RPL7A	RPLP2	MGAT4C	RCC1	DAD1	NMT1	MGAT4A	NMT2	RPL13A	MGAT4B	STT3A	PDCD6IP	RPS3A	MAN1B1	RNMT	RPL37A	ST6GALNAC3	RPL10	RANBP1	ST6GALNAC4	RPL12	RNGTT	TXNRD1	RPL11	RPL36A	RPS27L	HMGA1	PSIP1	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	FKBP4	CD4	SRC	NELFB	TGFB1	PTGES3	AVP	NOS2	VPS33B	CORO1A	RAB7A	TRIM27	CREB1	VAMP1	HIST2H2AB	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	HIST1H2AI	HIST1H2AH	HIST1H2AK	HIST2H2BF	HIST3H2A	LTF	NCBP1	NCBP2	PDZD3	IPO5	KPNA7	KPNA4	KPNA5	KPNA2	KPNA3	KPNA1	GTF2F1	GTF2F2	KPNB1	CPSF4	EIF2AK2	AHCYL1	ISG15	CALR	CD3G	PRKX	GRSF1	FCGR3A	CLTC	FCGR1A	CLTA	YES1	PARP1	DNAJC3	FGR	FCGR2A	CANX	PABPN1	RAN	RB1	NUP107	NUP188	HIST1H2AE	HIST1H2AD	BANF1	HIST3H2BB	HIST1H2AC	HIST1H2AB	NUP214	NUP210	HIST1H2AJ	NUP93	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	NUP205	CCNH	POM121	CHD4	CHD3	HIST1H3J	AAAS	NUP160	MTA1	HIST1H3A	NUP85	RBBP4	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	RBBP7	HIST1H3I	MTA2	HIST1H3B	MTA3	HIST1H3C	MBD3	HIST1H3D	HIST1H3E	GTF2H1	NUP155	GTF2H2	GTF2H3	GTF2H4	HIST1H4K	GATAD2B	HIST1H4L	GTF2H5	GATAD2A	MRC1	CDK7	NUP153	ERCC3	HIST1H4A	HIST1H4B	ERCC2	HIST1H4H	HIST1H4I	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	HIST2H2AC	ZBP1	NUP62	TBK1	NDC1	SEC13	NUP133	HIST2H2BE	HIST4H4	NUP50	NUP54	EZH2	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	MAPK1	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	SLC25A5	SLC25A4	SLC25A6	CD9	GLP1R	VIPR1	VIPR2	SCT	ADM	PTH1R	CYSLTR2	GLP2R	PTH2R	GIP	ADCYAP1	CRH	HSP90AB1	IAPP	CALCA	RAMP2	ADCYAP1R1	RAMP3	CALCRL	CALCB	GIPR	PTH	PSMD8	PSMD9	PTH2	PSMD6	PTHLH	PSMD7	CRHR1	PSMD4	GHRHR	PSMD5	PSMD2	CALCR	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	FZD7	PSMA1	PSMA2	PSME3	PSME4	SCTR	IGKV2-28	PSME1	IGKV1-12	PSME2	IGKV3D-20	GCG	PSMD10	ADM2	IGKV2D-28	PSMB11	GHRH	PSMD12	VIP	IGKV4-1	RAMP1	PSMD11	PSMD14	PSMD13	IGKV2D-30	PSMB10	PSMA7	STX1B	RELA	IGKV3-11	LYN	PSMA8	PSMB6	IGKV5-2	PSMB7	PSMB4	PSMB5	STX1A	XRCC6	PSMB2	XRCC5	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	NFKB1	PSMB9	CBX1	PSMC5	PSMC6	PSMC3	AP1G1	PSMC4	PACS1	PSMC1	AP1B1	PSMC2	AP1S2	AP1S1	AP1S3	HLA-A	B2M	AP1M2	AP1M1	SUMO1	UBE2I	VHL	RIPK1	IFNGR1	IFNGR2	ITGB1	IL6R	SH3GL2	UVRAG	PARP16	PARP14	PARP10	PARP6	PARP4	PARP9	LCK	PARP8	BECN1	GPS2	CD28	FYN	GSK3B	EED	PAK2	ATP6V1H	CTDP1	ELL	CCNT1	SUPT4H1	TCEB3	TCEB2	TCEB1	NELFA	NELFCD	TCEB3C	TCEB3CL	TCEB3B	NELFE	SUPT16H	SSRP1	SUPT5H	CDK9	TCEA1	TCEB3CL2	SFPQ	HNRNPK	ZCRB1	FKBP1A	NCOR2	NCOR1	CDH1	DDX5	ADAM17	CTSL	ADRB1	SNAP25	ADRB2	SV2C	HTR4	CTSG	SV2B	SV2A	HTR6	HTR7	TBP	HRH2	DRD1	CHMP1A	DRD5	TAAR8	TAAR9	TAAR6	TAAR5	TAAR2	TAAR1	ADRB3	FURIN	HDAC3	CEBPD	ARID4A	ARID4B	COMT	NR3C1	ITGA4	IL1R1	SIGMAR1	ATP1B3	ATP1B2	TYK2	ATP1B1	SAP30	BRMS1	IFNAR1	ATP1A4	ATP1A3	ATP1A2	ATP1A1	SAP30L	S1PR1	SAP18	SUDS3	BRD4	CRBN	STAT2	REST	FXYD4	FXYD3	IMPDH1	IMPDH2	FXYD2	FXYD1	FXYD7	FXYD6	PDCD1	CD8B	
HYALURONAN BIOSYNTHESIS AND EXPORT%REACTOME DATABASE ID RELEASE 74%2142850	Hyaluronan biosynthesis and export	HAS1	CEMIP	HAS3	ABCC5	HAS2	
SMAD2 3 MH2 DOMAIN MUTANTS IN CANCER%REACTOME DATABASE ID RELEASE 74%3315487	SMAD2 3 MH2 Domain Mutants in Cancer	SMAD2	SMAD3	SMAD4	
DOWNREGULATION OF SMAD2 3:SMAD4 TRANSCRIPTIONAL ACTIVITY%REACTOME DATABASE ID RELEASE 74%2173795	Downregulation of SMAD2 3:SMAD4 transcriptional activity	RPS27A	UBE2D1	TGIF1	TGIF2	SKIL	UBA52	TRIM33	PARP1	NEDD4L	SMAD4	SMAD2	SMURF2	SMAD3	USP9X	RNF111	HDAC1	SKI	UBB	UBE2D3	NCOR2	PPM1A	UBC	NCOR1	
ABACAVIR TRANSPORT AND METABOLISM%REACTOME DATABASE ID RELEASE 74%2161522	Abacavir transport and metabolism	ABCG2	SLC22A2	ADH1A	SLC22A1	PCK1	NT5C2	ADAL	ABCB1	GUK1	SLC22A3	
EXTENSION OF TELOMERES%REACTOME%R-HSA-180786.2	Extension of Telomeres	RUVBL1	NOP10	CCNA2	CCNA1	RUVBL2	SHQ1	PIF1	TERT	RTEL1	BLM	RPA1	RPA2	CDK2	WRAP53	RPA3	PRIM2	DSCC1	PRIM1	CHTF18	WRN	CHTF8	OBFC1	CTC1	POLA1	POLA2	TEN1	DNA2	TINF2	TERF1	TERF2	POT1	TERF2IP	ACD	GAR1	ANKRD28	RFC5	RFC3	FEN1	PCNA	RFC4	RFC1	LIG1	RFC2	POLD3	POLD4	POLD1	POLD2	DKC1	PPP6C	NHP2	PPP6R3	
SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 74%1660499	Synthesis of PIPs at the plasma membrane	PTEN	PIP5K1C	RAB14	RAB5A	BMX	MTMR2	INPP5D	MTMR9	PIK3C2A	MTM1	ARF1	PIK3CD	PIK3CB	PIK3CG	PIK3R5	INPPL1	PIK3R6	PIP5K1A	PIP5K1B	PIP4K2A	PIP4K2B	PIP4K2C	PTPN13	PIK3R3	PIK3R2	PIK3R1	MTMR14	SBF2	PIK3CA	PIK3C2G	PIK3C2B	RAB4A	OCRL	PI4K2B	RUFY1	MTMR1	INPP4A	MTMR3	INPP4B	MTMR8	PI4K2A	SYNJ2	MTMR6	INPP5J	INPP5K	PLEKHA1	PLEKHA5	PLEKHA6	SYNJ1	PLEKHA3	PLEKHA4	PLEKHA8	
DEFECTIVE SLC6A5 CAUSES HYPEREKPLEXIA 3 (HKPX3)%REACTOME DATABASE ID RELEASE 74%5619089	Defective SLC6A5 causes hyperekplexia 3 (HKPX3)	SLC6A5	
ACTIVATION OF THE PRE-REPLICATIVE COMPLEX%REACTOME%R-HSA-68962.3	Activation of the pre-replicative complex	POLA2	MCM7	MCM8	CDC7	MCM3	MCM4	GMNN	MCM10	MCM5	DBF4	RPA4	MCM6	MCM2	ORC5	ORC4	ORC6	ORC1	ORC3	ORC2	CDT1	CDC6	RPA1	RPA2	CDK2	POLE4	RPA3	POLE2	CDC45	POLE3	PRIM2	POLE	PRIM1	POLA1	
SCAVENGING OF HEME FROM PLASMA%REACTOME DATABASE ID RELEASE 74%2168880	Scavenging of heme from plasma	CD163	AMBP	JCHAIN	LRP1	HBB	HBA2	IGKV2-28	HBA1	IGKV1-12	IGKV3D-20	APOL1	IGKV2D-28	HP	IGKV4-1	APOA1	IGKV2D-30	ALB	HPR	IGKV3-11	IGKV5-2	HPX	IGHA1	
APC TRUNCATION MUTANTS HAVE IMPAIRED AXIN BINDING%REACTOME DATABASE ID RELEASE 74%5467337	APC truncation mutants have impaired AXIN binding	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	PPP2R1B	AMER1	AXIN1	APC	
PASSIVE TRANSPORT BY AQUAPORINS%REACTOME DATABASE ID RELEASE 74%432047	Passive transport by Aquaporins	MIP	AQP8	AQP4	AQP2	AQP3	AQP10	AQP12A	AQP1	AQP11	AQP9	AQP7	AQP6	AQP5	
DEFECTIVE COFACTOR FUNCTION OF FVIIIA VARIANT%REACTOME DATABASE ID RELEASE 74%9672396	Defective cofactor function of FVIIIa variant	F8	F10	F9	
DISEASES ASSOCIATED WITH VISUAL TRANSDUCTION%REACTOME%R-HSA-2474795.2	Diseases associated with visual transduction	RBP1	NAPEPLD	RDH5	LRAT	STRA6	ABCA4	OPN1SW	RBP4	OPN1MW	TTR	OPN1LW	RDH12	OPN1MW2	RLBP1	
SODIUM CALCIUM EXCHANGERS%REACTOME%R-HSA-425561.1	Sodium Calcium exchangers	SLC8B1	SLC8A3	SLC24A5	SRI	SLC8A1	SLC8A2	SLC24A2	SLC24A1	SLC24A4	SLC24A3	
TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX%REACTOME DATABASE ID RELEASE 74%9694676	Translation of Replicase and Assembly of the Replication Transcription Complex	MAP1LC3B	CHMP2B	CHMP2A	CHMP4C	CHMP4B	CHMP3	CHMP4A	CHMP6	CHMP7	PIK3R4	UVRAG	PIK3C3	BECN1	
REGULATION OF IGF ACTIVITY BY IGFBP%REACTOME%R-HSA-381426.2	Regulation of IGF Activity by IGFBP	TNC	PENK	TGOLN2	CP	TF	FBN1	IGFBP7	GZMH	KLK3	CST3	VCAN	APOA1	GPC3	MEN1	PNPLA2	MSLN	LTBP1	MIA3	BMP4	IGFBP1	ANO8	FGF23	CKAP4	FUCA2	MFI2	SPARCL1	IL6	HRC	FSTL1	GOLM1	DMP1	BMP15	ITIH2	LGALS1	MATN3	IGFBP3	ADAM10	MXRA8	CDH2	CHRDL1	ENAM	MFGE8	KLK2	CSF1	PRKCSH	FSTL3	LAMB2	BPIFB2	PDIA6	RCN1	EVA1A	LAMC1	CHGB	IGFBP2	PAPPA	IGFALS	MGAT4A	KLK1	IGFBP6	PAPPA2	APLP2	WFS1	SERPINA10	PRSS23	PCSK9	CTSG	TIMP1	AFP	SDC2	SCG3	KTN1	NUCB1	MMP1	NOTUM	MMP2	IGFBP5	SERPINA1	APOA2	IGFBP4	IGF2	APOA5	DNAJC3	IGF1	AMBN	CALU	TMEM132A	CYR61	MEPE	PLG	SPP1	APOE	APOB	LAMB1	QSOX1	AHSG	MBTPS1	APOL1	STC2	KLK13	FAM20C	VWA1	FAM20A	ALB	SPP2	C3	P4HB	C4A	FN1	GAS6	APP	SERPINC1	KNG1	SHISA5	SCG2	AMELX	FGA	SERPIND1	HSP90B1	FGG	AMTN	F2	F5	PROC	VGF	
ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1%REACTOME DATABASE ID RELEASE 74%418592	ADP signalling through P2Y purinoceptor 1	GNGT1	GNGT2	PLA2G4A	GNG12	GNG11	GNG13	MAPK14	GNA14	GNB2	GNA15	GNA11	GNB1	GNG3	GNAQ	GNB4	GNG10	GNB3	GNG2	GNB5	GNG5	GNG4	GNG7	GNG8	P2RY1	
DEFECTIVE SLC34A3 CAUSES HEREDITARY HYPOPHOSPHATEMIC RICKETS WITH HYPERCALCIURIA (HHRH)%REACTOME%R-HSA-5619097.1	Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH)	SLC34A3	
SEMA3A PAK DEPENDENT AXON REPULSION%REACTOME DATABASE ID RELEASE 74%399954	Sema3A PAK dependent Axon repulsion	PAK3	PAK2	FYN	PLXNA2	HSP90AB1	PLXNA1	LIMK1	RAC1	PLXNA4	PLXNA3	NRP1	FES	HSP90AA1	CFL1	PAK1	SEMA3A	
SYNDECAN INTERACTIONS%REACTOME%R-HSA-3000170.2	Syndecan interactions	ITGB5	TRAPPC4	TNC	PRKCA	ITGAV	SDC4	THBS1	FGF2	SDC3	ITGA2	CASK	SDC1	ITGA6	TGFB1	ITGB1	VTN	ACTN1	ITGB4	SDC2	ITGB3	
RUNX3 REGULATES RUNX1-MEDIATED TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%8951911	RUNX3 regulates RUNX1-mediated transcription	CBFB	RUNX3	
NTRK3 AS A DEPENDENCE RECEPTOR%REACTOME%R-HSA-9603505.1	NTRK3 as a dependence receptor	NTRK3	BAX	NELFB	
SIGNALING BY PDGFRA TRANSMEMBRANE, JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS%REACTOME DATABASE ID RELEASE 74%9673767	Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	NRAS	SOS1	HRAS	PIK3R2	PDGFRA	PIK3R1	PIK3CA	STAT1	PIK3CB	STAT3	
INTERLEUKIN-9 SIGNALING%REACTOME DATABASE ID RELEASE 74%8985947	Interleukin-9 signaling	IL2RG	IL9R	JAK3	JAK1	STAT5A	STAT5B	STAT1	IL9	STAT3	
BICARBONATE TRANSPORTERS%REACTOME%R-HSA-425381.2	Bicarbonate transporters	SLC4A7	AHCYL2	SLC4A8	SLC4A1	SLC4A9	SLC4A2	SLC4A3	SLC4A4	SLC4A5	SLC4A10	
FREE FATTY ACID RECEPTORS%REACTOME DATABASE ID RELEASE 74%444209	Free fatty acid receptors	GPR31	FFAR3	FFAR2	FFAR4	FFAR1	
MECP2 REGULATES TRANSCRIPTION OF GENES INVOLVED IN GABA SIGNALING%REACTOME DATABASE ID RELEASE 74%9022927	MECP2 regulates transcription of genes involved in GABA signaling	GAD1	GAD2	
RAB REGULATION OF TRAFFICKING%REACTOME DATABASE ID RELEASE 74%9007101	Rab regulation of trafficking	DENND3	RAB21	OPTN	RAB10	RAB14	ST5	RAB5A	RAB12	RAB13	RAB1A	RAB6A	RINL	RAB6B	TBC1D10C	TBC1D10A	RAB39A	RAB1B	TBC1D10B	RIN3	ULK1	RIN1	RIN2	RAB39B	RAB27A	RAB27B	MON1A	MON1B	GDI1	GDI2	MAP1LC3B	RAB8B	RAB33A	RAB33B	RAB7B	RABGAP1	SBF1	ALS2CL	RAB11B	DENND5B	TRAPPC12	TRAPPC11	TSC2	DENND5A	TSC1	CHM	TRAPPC13	SBF2	TRAPPC2L	TBC1D20	TBC1D24	TBC1D25	DENND6B	DENND6A	TBC1D13	RAB3IP	TBC1D14	TBC1D17	RAB11A	TBC1D15	TBC1D16	DENND4B	DENND4A	CCZ1	RIC1	RGP1	TRAPPC6A	TBC1D2	RABEP1	TBC1D3	RABGEF1	ALS2	TRAPPC6B	RAB18	TBC1D7	RAB3GAP2	RAB9A	GABARAPL2	RAB3GAP1	SYTL1	RAB9B	GAPVD1	GABARAP	CCZ1B	DENND1C	DENND1B	DENND1A	DENND2D	DENND2C	DENND2A	RAB3IL1	ARF6	GGA2	GGA1	GGA3	CHML	TRAPPC10	RAB3A	RAB32	RAB31	RAB35	RAB38	RAB5B	RAB5C	TRAPPC2	TRAPPC3	AKT2	RAB4A	AKT3	TRAPPC1	YWHAE	ANKRD27	AKT1	TRAPPC4	TRAPPC5	HPS1	HPS4	TRAPPC8	TRAPPC9	RAB7A	RAB8A	
ARL13B-MEDIATED CILIARY TRAFFICKING OF INPP5E%REACTOME DATABASE ID RELEASE 74%5624958	ARL13B-mediated ciliary trafficking of INPP5E	PDE6D	ARL13B	INPP5E	
ADORA2B MEDIATED ANTI-INFLAMMATORY CYTOKINES PRODUCTION%REACTOME%R-HSA-9660821.1	ADORA2B mediated anti-inflammatory cytokines production	ADCY2	ADCY1	ADCY8	ADCY7	CREB1	ADCY6	ADCY5	GNG12	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	PRKAR2B	GLP1R	VIPR1	VIPR2	SCT	ADM	PTH1R	CYSLTR2	IL6	GLP2R	PTH2R	GIP	ADCYAP1	CRH	IAPP	CALCA	RAMP2	ADCYAP1R1	RAMP3	CALCRL	CALCB	GIPR	PTH	PTH2	PTHLH	CRHR1	GHRHR	CALCR	SCTR	GCG	ADM2	GHRH	VIP	RAMP1	RXFP1	ADRB1	RXFP2	GPR176	ADRB2	GNAT3	HTR4	PTGDR	HTR6	HTR7	LHB	HRH2	CRHR2	DRD1	MC2R	CGA	GPR15	DRD5	MC1R	TAAR8	PRKX	GPR27	TAAR9	GPR25	GPR20	TAAR6	MC4R	GPR39	FSHB	GPR32	TAAR5	TAAR2	GPBAR1	MC3R	TAAR1	FSHR	NPSR1	ADRB3	PTGER4	GPR45	PTGER2	GNAI3	GNAI1	GNAI2	NPS	GPR150	GPHA2	P2RY11	MC5R	GPHB5	LHCGR	GNAZ	GPR83	GPR84	AVP	RLN2	ADORA2A	RLN3	INSL3	TSHB	PRKACG	PTGIR	PRKACB	AVPR2	GNGT1	ADORA2B	TSHR	GNGT2	POMC	ADCY9	PRKAR1B	PRKAR1A	PRKACA	PRKAR2A	GNAS	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	ADCY4	ADCY3	
DEFECTIVE POMT2 CAUSES MDDGA2, MDDGB2 AND MDDGC2%REACTOME DATABASE ID RELEASE 74%5083629	Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2	POMT1	DAG1	POMT2	
NEGATIVE REGULATORS OF RIG-I MDA5 SIGNALING%REACTOME%R-HSA-936440.4	Negative regulators of RIG-I MDA5 signaling	IFIH1	RNF135	MAVS	UBE2D2	NLRC5	PIN1	UBE2D1	TBK1	ITCH	IRF3	UBA7	TRAF3	UBA52	UBE2K	CYLD	TNFAIP3	DDX58	NLRX1	RNF216	UBB	ATG5	UBE2D3	UBC	RPS27A	UBE2L6	RNF125	HERC5	ISG15	TAX1BP1	TRIM25	ATG12	PCBP2	OTUD5	IKBKE	
FOLDING OF ACTIN BY CCT TRIC%REACTOME%R-HSA-390450.2	Folding of actin by CCT TriC	CCT4	CCT7	ACTB	CCT6A	TCP1	CCT6B	CCT3	CCT8	CCT2	CCT5	
PEPTIDE HORMONE BIOSYNTHESIS%REACTOME%R-HSA-209952.1	Peptide hormone biosynthesis	FSHB	INHBB	INHBE	INHBA	LHB	POMC	CGA	TSHB	INHA	PCSK1	INHBC	
CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION%REACTOME%R-HSA-69273.6	Cyclin A B1 B2 associated events during G2 M transition	WEE1	PPME1	FOXM1	PKMYT1	LCMT1	CDC25A	PPP2R2A	PPP2R3B	CCNA2	CDC25C	CCNA1	CDC25B	XPO1	CCNB2	CCNH	CCNB1	PPP2CA	PPP2CB	PPP2R1A	PLK1	CDK2	CDK1	CDK7	PPP2R1B	MNAT1	
ACTIVATION OF SMO%REACTOME DATABASE ID RELEASE 74%5635838	Activation of SMO	EVC	GAS8	ARRB1	ARRB2	CSNK1A1	SMO	KIF3A	PTCH1	DHH	IHH	ADRBK1	CDON	SHH	EVC2	BOC	IQCE	GAS1	EFCAB7	
FATTY ACYL-COA BIOSYNTHESIS%REACTOME%R-HSA-75105.6	Fatty acyl-CoA biosynthesis	HACD3	HACD2	CBR4	HACD4	OLAH	ACSL4	ACSL3	PPT1	PPT2	MORC2	ELOVL4	ELOVL6	ELOVL7	ACSF3	ACSBG1	ACSBG2	SLC27A3	FASN	ACSL1	TECRL	SLC25A1	ACACA	SCD5	HSD17B12	ACSL6	ACSL5	ELOVL1	ACLY	SCD	ELOVL5	ELOVL2	ELOVL3	TECR	HSD17B3	HACD1	HSD17B8	
RPIA DEFICIENCY: FAILED CONVERSION OF RU5P TO R5P%REACTOME DATABASE ID RELEASE 74%6791461	RPIA deficiency: failed conversion of RU5P to R5P	RPIA	
SIGNALING BY FGFR1%REACTOME DATABASE ID RELEASE 74%5654736	Signaling by FGFR1	FLRT3	MAPK3	PTPN11	FGF20	UBA52	FGF23	FGF22	GAB1	CBL	NRAS	PLCG1	SOS1	MKNK1	HRAS	UBB	FGF18	SPRY2	PIK3R1	PIK3CA	UBC	FLRT2	FGF10	FLRT1	RPS27A	PPP2CA	FGFRL1	PPP2CB	MAPK1	SPRED2	PPP2R1A	SPRED1	ANOS1	FRS2	FRS3	FGF1	FGF2	FGF3	FGF4	FGF6	FGF9	BRAF	
PI3K CASCADE%REACTOME DATABASE ID RELEASE 74%109704	PI3K Cascade	IRS1	PTPN11	FGF20	FGF23	GAB2	FGF22	GAB1	FGF16	PDPK1	FGF19	PIK3R2	FGF18	PIK3R1	FGFR4	PIK3CA	AKT2	TLR9	FGF10	FLT3	PDE3B	THEM4	TRIB3	KLB	FLT3LG	FRS2	IRS2	FGF1	PIK3CB	FGF2	FGF3	PIK3R4	FGF4	FGF6	FGF7	FGF9	PIK3C3	
ENDOSOMAL VACUOLAR PATHWAY%REACTOME DATABASE ID RELEASE 74%1236977	Endosomal Vacuolar pathway	LNPEP	CTSV	HLA-B	CTSS	HLA-C	HLA-F	HLA-G	HLA-E	CTSL	HLA-A	B2M	
METABOLISM OF POLYAMINES%REACTOME%R-HSA-351202.3	Metabolism of polyamines	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	OAZ1	PSMA7	OAZ2	PSMA8	OAZ3	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	ODC1	NQO1	AGMAT	SAT1	SMS	AZIN2	AZIN1	AMD1	SRM	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PAOX	PSMA5	
SMAC, XIAP-REGULATED APOPTOTIC RESPONSE%REACTOME%R-HSA-111469.3	SMAC, XIAP-regulated apoptotic response	APAF1	DIABLO	XIAP	CASP9	CASP3	CASP7	CYCS	
DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B%REACTOME%R-HSA-9668250.1	Defective factor IX causes hemophilia B	GP1BA	GP5	GP9	F8	F10	F9	GGCX	GP1BB	F11	
REGULATION OF ACTIN DYNAMICS FOR PHAGOCYTIC CUP FORMATION%REACTOME DATABASE ID RELEASE 74%2029482	Regulation of actin dynamics for phagocytic cup formation	MAPK3	IGKV2-28	IGKV1-12	IGKV3D-20	IGKV2D-28	ABL1	IGKV4-1	IGKV2D-30	IGKV3-11	IGKV5-2	NF2	MAPK1	CD3G	CYFIP2	NCKAP1	FCGR3A	CYFIP1	RAC1	FCGR1A	WIPF1	ARPC1B	WIPF2	FCGR2A	ARPC1A	VAV1	WIPF3	BRK1	WASL	ACTB	DOCK1	ACTG1	NCK1	ACTR3	VAV3	ACTR2	CDC42	VAV2	MYH2	ELMO1	BTK	ELMO2	WAS	NCKIPSD	NCKAP1L	WASF1	WASF2	WASF3	MYO10	MYO5A	ARPC4	MYO9B	ARPC5	LIMK1	BAIAP2	MYO1C	ABI2	ARPC2	ARPC3	ABI1	MYH9	IGHG4	IGHG1	IGHG2	SYK	CRK	HSP90AB1	HSP90AA1	CFL1	PTK2	PAK1	
DEFECTIVE CYP11A1 CAUSES ADRENAL INSUFFICIENCY, CONGENITAL, WITH 46,XY SEX REVERSAL (AICSR)%REACTOME%R-HSA-5579026.1	Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)	FDX1	FDXR	FDX1L	CYP11A1	
PROGRESSIVE TRIMMING OF ALPHA-1,2-LINKED MANNOSE RESIDUES FROM MAN9 8 7GLCNAC2 TO PRODUCE MAN5GLCNAC2%REACTOME DATABASE ID RELEASE 74%964827	Progressive trimming of alpha-1,2-linked mannose residues from Man9 8 7GlcNAc2 to produce Man5GlcNAc2	MAN1C1	MAN1A2	MAN1A1	
G2 PHASE%REACTOME%R-HSA-68911.3	G2 Phase	E2F3	CDK2	E2F1	CCNA2	CCNA1	
DEPOLYMERISATION OF THE NUCLEAR LAMINA%REACTOME%R-HSA-4419969.1	Depolymerisation of the Nuclear Lamina	PRKCB	LMNB1	PRKCA	LEMD3	LEMD2	EMD	CTDNEP1	CDK1	LPIN1	LPIN2	LPIN3	CNEP1R1	CCNB1	
INTERLEUKIN-20 FAMILY SIGNALING%REACTOME DATABASE ID RELEASE 74%8854691	Interleukin-20 family signaling	IFNL2	JAK3	IFNL1	JAK1	PTPN11	IFNL3	TYK2	STAT4	STAT2	IFNLR1	IL22	IL20	IL26	IL24	STAT5A	IL19	IL20RA	STAT5B	IL20RB	IL22RA2	STAT1	IL22RA1	STAT3	JAK2	IL10RB	
PKA-MEDIATED PHOSPHORYLATION OF KEY METABOLIC FACTORS%REACTOME DATABASE ID RELEASE 74%163358	PKA-mediated phosphorylation of key metabolic factors	PFKFB1	MLXIPL	PRKACA	PRKACG	PRKACB	
TOLERANCE BY MTB TO NITRIC OXIDE PRODUCED BY MACROPHAGES%REACTOME DATABASE ID RELEASE 74%1222538	Tolerance by Mtb to nitric oxide produced by macrophages	
GOLGI ASSOCIATED VESICLE BIOGENESIS%REACTOME%R-HSA-432722.3	Golgi Associated Vesicle Biogenesis	SH3D19	DNAJC6	FTL	DNM2	DTNBP1	HIP1R	TPD52L1	TGOLN2	NECAP1	BLOC1S4	BLOC1S6	BLOC1S1	BLOC1S3	SNAPIN	PIK3C2A	IGF2R	AP1G1	AP1B1	AP1S2	AP1S1	ARF1	AP1S3	SNX2	HSPA8	SNX9	AP1M2	SNX5	AP1M1	TBC1D8B	CLINT1	AP3S1	PUM1	VAMP8	VAMP7	AP4E1	VAMP2	GAK	TPD52	AP3B1	SORT1	GOLGB1	YIPF6	SH3GL2	RAB5C	TXNDC5	NAPA	OCRL	ARRB1	TFRC	FTH1	CPD	AP4B1	ACBD3	PICALM	
GLUCOCORTICOID BIOSYNTHESIS%REACTOME%R-HSA-194002.2	Glucocorticoid biosynthesis	HSD11B1	POMC	HSD11B2	CYP17A1	CYP11B2	CYP11B1	SERPINA6	CYP21A2	HSD3B2	HSD3B1	
APC-CDC20 MEDIATED DEGRADATION OF NEK2A%REACTOME DATABASE ID RELEASE 74%179409	APC-Cdc20 mediated degradation of Nek2A	UBE2D1	CDC23	CDC26	CDC27	ANAPC7	UBA52	UBE2E1	ANAPC4	BUB1B	ANAPC5	CDC20	UBB	BUB3	ANAPC1	MAD2L1	ANAPC2	ANAPC15	ANAPC16	UBC	ANAPC10	ANAPC11	RPS27A	UBE2C	UBE2S	NEK2	CDC16	
REGULATION OF THYROID HORMONE ACTIVITY%REACTOME DATABASE ID RELEASE 74%350864	Regulation of thyroid hormone activity	DIO1	DIO2	DIO3	
DEFECTIVE BASE EXCISION REPAIR ASSOCIATED WITH NTHL1%REACTOME DATABASE ID RELEASE 74%9616333	Defective Base Excision Repair Associated with NTHL1	NTHL1	
DEFECTIVE MISMATCH REPAIR ASSOCIATED WITH MSH3%REACTOME%R-HSA-5632927.1	Defective Mismatch Repair Associated With MSH3	MSH2	MSH3	
DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS%REACTOME DATABASE ID RELEASE 74%5663202	Diseases of signal transduction by growth factor receptors and second messengers	BCL2L11	AKAP9	VCP	UBA52	SEL1L	HEY1	HEY2	CUL1	UBB	ERLIN2	UBC	RPS27A	FIP1L1	TBL1X	PPP2CA	PPP2CB	MAPK1	ERBB2IP	STAT5A	STAT5B	KANK1	PIK3CD	IRS2	PIK3CB	VAV1	FGFR1OP	DERL2	ERLEC1	OS9	JAK2	STRN	TRAT1	TBL1XR1	PIK3AP1	SMAD4	RPS6KB2	IHH	SHH	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	CUX1	DHH	FOXO6	FOXO4	PSMD8	PSMD9	HEYL	PSMD6	PSMD7	PSMD4	GSK3A	PSMD5	PSMD2	PSMD3	AMER1	PSMD1	AXIN1	APC	CHUK	PSMA5	PSMA6	PSMA3	WNT3A	PSMA4	CCNC	PSMA1	PSMA2	PSME3	PSME4	PSME1	FZD8	PSME2	PTEN	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	NOTCH1	PSMD13	LMNA	YWHAB	PSMB10	PSMA7	LYN	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	SYVN1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	SNW1	ESR1	IRS1	SRC	HDAC6	CD19	SMAD2	SMAD3	TGFB1	PRR5	CD86	TGFBR1	PDPK1	TGFBR2	MAPKAP1	FN1	CD80	PIK3R3	PIK3R2	PIK3R1	RAC2	MTOR	PIK3CA	LCK	AKT2	AKT3	MLST8	CD28	AKT1	RBX1	ARAF	FYN	RICTOR	FRS2	GSK3B	CAMK2A	EREG	BTC	TLN1	MAML2	MAML1	PDGFB	TGFA	PSEN2	RBPJ	IQGAP1	DLL1	DLL4	APH1A	BRAP	NEURL1B	APH1B	BRAF	CREBBP	EP300	HES1	HES5	CTBP1	JAG2	TCF7L2	PSENEN	JAG1	MIB2	FZD5	RAF1	AREG	MIB1	FZD4	FZD6	CREB1	NEURL1	CSNK1A1	FOXO1	MAML3	HHAT	MAMLD1	GAB2	DUSP8	DUSP9	DUSP6	DUSP7	CTNNB1	CNKSR2	APBB1IP	CNKSR1	MRAS	PTPN12	KIT	AGK	HBEGF	SHOC2	MYC	EPGN	FOXO3	KLB	TNKS2	ITGA2B	TNKS	PEBP1	RAC1	FGF1	FGF2	FGF3	FGF4	PPP1CC	FGF6	FGF7	FGF9	HDAC2	HDAC1	PDGFRB	PDGFRA	MAP2K1	CASP9	MAP2K2	HGF	VCL	PHB	ETV6	RAP1B	RAP1A	KIAA1549	MPRIP	FGF20	AGTRAP	MARK3	AP3B1	FGF23	SND1	FGF22	PAPD7	ESRP1	FGF16	KDM7A	ERBB2	FAM114A2	ZC3HAV1	TRAK1	PAPSS1	FXR1	ATG7	FGF19	TSC2	QKI	FGF18	NF1	CLCN6	FGFR4	FAM131B	FKBP1A	AGGF1	MAP3K11	NCOR2	NCOR1	FGF10	ITGB3	NCBP1	BAD	NCBP2	AKT1S1	ARRB1	ARRB2	DUSP16	ZMYM2	SPRED3	FGFR1OP2	SPRED2	TRIM24	SPRED1	DUSP10	MYO18A	LRRFIP1	BCR	PPP2R5E	BAG4	KSR1	CPSF6	PPP2R5B	STAT1	PPP2R5A	STAT3	PPP2R5D	FGFR3	NRG1	FGFR2	PPP2R5C	FGFR1	KSR2	ADAM10	NRG2	NRG3	ADAM17	NRG4	MET	CAMK2B	PSEN1	CAMK2D	MAPK3	CDKN1A	CSK	CDKN1B	NCSTN	CAMK2G	PTPN11	MDM2	HDAC4	KRAS	HDAC5	SHC1	HDAC8	EGF	GAB1	HDAC9	CDK8	CBL	HDAC7	EGFR	NRAS	CDC37	PLCG1	SOS1	HRAS	WDR48	HDAC10	HDAC11	GTF2F1	PORCN	KDR	GTF2F2	YES1	DKK1	DKK2	DKK4	PPP2R1B	KREMEN1	KREMEN2	HDAC3	RNF43	ESR2	NR4A1	LRP5	LRP6	CTBP2	PPP1CB	FGB	PPP2R1A	FGA	RHOG	VWF	GOLGA4	FGG	KAT2B	SKP1	KAT2A	HSP90AA1	
MISCELLANEOUS TRANSPORT AND BINDING EVENTS%REACTOME%R-HSA-5223345.4	Miscellaneous transport and binding events	CTNS	AZGP1	TUSC3	ANKH	MAGT1	MRS2	MMGT1	PIP	ADD1	PQLC2	ADD3	LRRC8C	ADD2	LRRC8D	LRRC8A	LRRC8B	LRRC8E	NIPA1	NIPAL4	NIPA2	NIPAL1	NIPAL2	DMTN	NIPAL3	
SODIUM PROTON EXCHANGERS%REACTOME DATABASE ID RELEASE 74%425986	Sodium Proton exchangers	SLC9A2	SLC9A3	SLC9A1	SLC9A4	SLC9A5	SLC9A6	SLC9A7	SLC9A8	SLC9A9	
DEPOSITION OF NEW CENPA-CONTAINING NUCLEOSOMES AT THE CENTROMERE%REACTOME%R-HSA-606279.1	Deposition of new CENPA-containing nucleosomes at the centromere	HIST2H2AC	H2AFJ	RUVBL1	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HJURP	ITGB3BP	HIST4H4	SMARCA5	OIP5	CENPA	STRA13	CENPC	NPM1	RSF1	HIST1H2BN	CENPT	MIS18BP1	HIST1H2BM	CENPU	HIST1H2BO	CENPW	APITD1	HIST1H2BJ	MIS18A	CENPH	HIST1H2BI	CENPI	HIST1H2BL	CENPK	CENPL	HIST1H2BK	CENPM	CENPN	HIST2H4A	CENPO	HIST2H4B	CENPP	CENPQ	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	RBBP4	RBBP7	HIST1H4K	HIST1H4L	CASC5	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
NEUTROPHIL DEGRANULATION%REACTOME DATABASE ID RELEASE 74%6798695	Neutrophil degranulation	DYNLL1	VCP	PYGB	AGL	GAA	RAB10	PYGL	RAB14	SLC15A4	PGM2	MME	ATP6AP2	GYG1	ANPEP	TBC1D10C	DYNC1H1	TUBB4B	ALAD	RAB27A	CTSZ	GDI2	FCGR3B	PLAUR	CTSC	APEH	SDCBP	GMFG	PGLYRP1	MCEMP1	CDK13	FUCA2	CXCR1	SIGLEC9	CXCR2	YPEL5	SIGLEC5	TOM1	BST1	VNN1	ACLY	ARL8A	NIT2	MAGT1	RNASET2	TMBIM1	ACPP	CANT1	DDOST	TSPAN14	LAMP2	PRKCD	C6orf120	SLPI	CRISPLD2	C16orf62	TMEM63A	SYNGR1	A1BG	NBEAL2	PSAP	HSPA8	CYFIP1	MAPK14	ACTR1B	RAP2C	PPBP	RAP2B	C1orf35	GCA	GNS	SERPINA3	ACTR2	ORM1	CPNE1	CPNE3	SRP14	ORM2	NCKAP1L	PLAU	C5AR1	DGAT1	ENPP4	QSOX1	AHSG	ADGRG3	ARPC5	CD63	GGH	CSNK2B	SLCO4C1	MS4A3	TNFAIP6	HSPA6	CHI3L1	MPO	SLC11A1	CHRNB4	PLD1	CYBB	PTX3	GLA	CDA	FRMPD3	GOLGA7	ARMC8	PLAC8	RAB7A	PLEKHO2	GRN	TMEM179B	IQGAP1	RAB3D	RAB44	SIRPB1	FRK	LAMP1	SLC44A2	LPCAT1	CLEC5A	KCMF1	ILF2	RAB37	UBR4	SIGLEC14	DSN1	FCAR	PKM	FGL2	ITGAX	RAB24	VAPA	CD47	AGPAT2	CPPED1	CALML5	VAT1	SLC2A5	LRRC7	CSTB	P2RX1	CST3	LAIR1	SVIP	QPCT	COTL1	MGST1	DBNL	DERA	GPI	GSN	APAF1	LTF	CLEC12A	TMEM30A	RNASE3	HK3	SCAMP1	RNASE2	PGAM1	FLG2	PADI2	VCL	AZU1	LYZ	ALDOC	HRNR	PIGR	ALDOA	TMC6	SERPINB10	SERPINB12	RAP1B	PFKL	RAP1A	LRG1	STK10	ATG7	OLFM4	S100A7	DEFA4	DEFA1	PTPRB	FAM47E-STBD1	LRMP	CECR1	HGSNAT	GLIPR1	FPR1	GALNS	FPR2	ANXA2	PTGES2	COMMD9	PRG2	PRG3	CYSTM1	CTSH	CD33	CD53	COMMD3	ARG1	DNAJC5	MLEC	PGRMC1	CREG1	KPNB1	HUWE1	EEF1A1	EEF2	DNAJC3	FGR	FCGR2A	CD68	OSTF1	CD93	ATAD3B	OSCAR	DOK3	CNN2	CXCL1	PRSS3	SPTAN1	FCN1	TARM1	CFD	DDX3X	TOLLIP	DYNLT1	CD59	CD55	MVP	DEFA1B	C3	PDAP1	S100P	TCN1	ABCA13	CFP	NHLRC3	UNC13D	CRACR2A	PRDX4	S100A9	S100A8	S100A11	GSDMD	PA2G4	S100A12	SERPINB3	PDXK	SERPINB1	NFAM1	SERPINB6	ITGAM	ASAH1	HPSE	ITGB2	HMGB1	METTL7A	AGA	ERP44	CD36	GUSB	ALOX5	GHDC	LTA4H	DYNC1LI1	EPX	ATP8A1	ATP11B	ATP11A	COPB1	FABP5	CLEC4C	CLEC4D	BPI	JUP	BRI3	TLR2	RAB6A	TRPM2	SURF4	CCT2	GM2A	IGF2R	MAPK1	MNDA	FOLR3	PTPRN2	ATP8B4	CCT8	STK11IP	IQGAP2	FAF2	TMEM173	MANBA	DNASE1L1	B4GALT1	HVCN1	LILRA3	SNAP29	LILRB2	LILRB3	CD300A	ANO6	DPP7	PKP1	DNAJC13	DSC1	TNFRSF1B	MAN2B1	CRISP3	HEBP2	CKAP4	MOSPD2	PAFAH1B2	CMTM6	ADGRE5	ADGRE3	STOM	PTPRC	HSP90AB1	PGM1	ITGAV	DSP	DSG1	PSMD6	PSMD7	PSMD2	PSMD3	PSMD1	DIAPH1	NDUFC2	PRDX6	PSMA5	PSMA2	GSTP1	RAB18	ACTR10	PSMD12	PSMD11	RAB9B	PSMD14	PSMD13	ITGAL	PSMB7	XRCC6	XRCC5	PSMB1	NFKB1	PSMC3	PSMC2	HLA-A	B2M	SIRPA	AP1M1	LGALS3	IST1	MIF	CAP1	IDH1	TICAM2	SELL	OLR1	CD14	FCER1G	CEACAM3	CD58	PTPN6	CEACAM1	CEACAM6	CEACAM8	TYROBP	FUCA1	NAPRT	CAT	RETN	TCIRG1	NEU1	FTH1	CTSA	ATP6V0C	FTL	GLB1	CAND1	ATP6V1D	NME2	HMOX2	ATP6V0A1	LCN2	AMPD3	APRT	PNP	HEXB	HBB	RAC1	ARSB	HLA-B	HLA-C	DOCK2	TTR	BST2	ALDH3B1	ORMDL3	PTAFR	ROCK1	PPIA	RHOA	CAB39	DEGS1	PPIE	CYB5R3	ARSA	LAMTOR2	LAMTOR1	LAMTOR3	CAPN1	PRSS2	ADAM10	ADAM8	PSEN1	CR1	NCSTN	PTPRJ	ELANE	SLC27A2	RAB4B	CTSS	NRAS	ACAA1	MMP25	SNAP25	TIMP2	C3AR1	CTSG	AP2A2	CTSD	CTSB	MMP8	MMP9	SERPINA1	NPC2	CD44	AOC1	VAMP8	HMHA1	SLC2A3	PYCARD	RAB3A	CYBA	HP	NFASC	RAB31	GPR84	RAB5B	RAB5C	TXNDC5	KRT1	TRAPPC1	PRCP	ARHGAP9	IMPDH1	IMPDH2	CD177	RHOG	RHOF	MGAM	CEP290	HSP90AA1	CHIT1	KCNAB2	TUBB	SNAP23	PRTN3	
PEROXISOMAL LIPID METABOLISM%REACTOME%R-HSA-390918.5	Peroxisomal lipid metabolism	AMACR	NUDT19	CROT	ABCD1	PECR	PHYH	ACOXL	SLC25A17	HACL1	SLC27A2	NUDT7	ACBD4	ACOT8	EHHADH	CRAT	HSD17B4	DECR2	ACOX2	ACOT6	ACAA1	HAO2	ACOT4	ACOX3	ACBD5	
CHEMOKINE RECEPTORS BIND CHEMOKINES%REACTOME DATABASE ID RELEASE 74%380108	Chemokine receptors bind chemokines	CXCL10	CCL5	CCL4	CCL3	ACKR4	ACKR3	ACKR2	CCR1	CXCR4	CXCL6	CCR9	CCR8	CXCL9	CCR7	CCR6	CCR4	CCR3	CCR2	CXCL3	CXCL5	CCR5	CCR10	PPBP	XCR1	CXCL13	CXCL16	CCL3L1	CCL13	CCL3L3	CCRL2	CX3CL1	CXCL1	CXCL2	CCL17	CCL16	CXCL8	CCL25	CCL21	CCL2	CXCL11	CCL28	CCL27	CXCR5	CXCR6	CXCR1	CXCR3	CXCR2	CCL7	CXCL12	CCL1	CCL11	XCL2	XCL1	CCL19	CX3CR1	CCL22	CCL20	PF4	
LYSINE CATABOLISM%REACTOME%R-HSA-71064.2	Lysine catabolism	AADAT	DLD	DLST	SLC25A21	CRYM	AASS	PIPOX	ALDH7A1	HYKK	OGDH	GCDH	PHYKPL	
PENTOSE PHOSPHATE PATHWAY DISEASE%REACTOME%R-HSA-6791465.1	Pentose phosphate pathway disease	RPIA	TALDO1	
DEFECTS OF FORMATION OF FIBRIN CLOT (CLOTTING CASCADE)%REACTOME%R-HSA-9651496.2	Defects of Formation of Fibrin Clot (Clotting Cascade)	TPST2	F10	TPST1	GGCX	VWF	KLKB1	GP1BB	F12	F11	GP1BA	F2	GP5	GP9	F8	F9	SERPING1	
TRANSCRIPTIONAL REGULATION BY SMALL RNAS%REACTOME%R-HSA-5578749.3	Transcriptional regulation by small RNAs	HIST2H2AC	H2AFJ	NUP62	NDC1	SEC13	NUP133	H2AFZ	H2AFX	H2AFV	AGO1	HIST2H2BE	AGO2	HIST4H4	NUP50	NUP54	TNRC6A	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	RAN	NUP107	NUP188	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	NUP214	NUP210	HIST1H2AJ	NUP93	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	NUP205	POM121	H2AFB1	HIST1H3J	AAAS	NUP160	HIST1H3A	NUP85	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	IPO8	NUP155	H3F3B	HIST1H4K	HIST1H4L	H3F3A	NUP153	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
NEPHRIN FAMILY INTERACTIONS%REACTOME%R-HSA-373753.3	Nephrin family interactions	SPTAN1	FYN	ACTN2	KIRREL3	KIRREL2	NCK2	KIRREL	MAGI2	PIK3CB	CD2AP	SPTBN1	NPHS1	CASK	IQGAP1	WASL	NCK1	PIK3R2	ACTN3	ACTN1	PIK3R1	ACTN4	PIK3CA	
DOWNREGULATION OF ERBB4 SIGNALING%REACTOME DATABASE ID RELEASE 74%1253288	Downregulation of ERBB4 signaling	WWP1	RPS27A	NEDD4	SRC	ITCH	UBB	UBC	UBA52	
MPS I - HURLER SYNDROME%REACTOME%R-HSA-2206302.2	MPS I - Hurler syndrome	IDUA	
DEFECTIVE AVP DOES NOT BIND AVPR1A,B AND CAUSES NEUROHYPOPHYSEAL DIABETES INSIPIDUS (NDI)%REACTOME DATABASE ID RELEASE 74%5619099	Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)	AVPR1B	AVPR1A	AVP	
ACYL CHAIN REMODELING OF DAG AND TAG%REACTOME%R-HSA-1482883.3	Acyl chain remodeling of DAG and TAG	DGAT2	DGAT1	PNPLA2	AWAT2	PNPLA3	DGAT2L6	MGLL	
IRAK1 RECRUITS IKK COMPLEX%REACTOME DATABASE ID RELEASE 74%937039	IRAK1 recruits IKK complex	IKBKB	UBE2N	PELI3	PELI2	TRAF6	PELI1	IKBKG	IRAK1	CHUK	UBE2V1	
CHOLINE CATABOLISM%REACTOME%R-HSA-6798163.2	Choline catabolism	BHMT	SLC44A1	DMGDH	ALDH7A1	CHDH	SARDH	
DEGRADATION OF BETA-CATENIN BY THE DESTRUCTION COMPLEX%REACTOME DATABASE ID RELEASE 74%195253	Degradation of beta-catenin by the destruction complex	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	CSNK1A1	TLE3	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	CUL1	CTNNB1	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PPP2CA	PSMC5	PPP2CB	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	FRAT1	FRAT2	HDAC1	PPP2R1B	ZRANB1	CTBP2	AES	TLE4	TLE2	TLE1	RBX1	PPP2R1A	GSK3B	PPP2R5E	BTRC	LEF1	PPP2R5B	TCF7	PPP2R5A	PPP2R5D	PPP2R5C	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	AMER1	PSMD1	AXIN1	APC	CTBP1	TCF7L2	PSMA5	TCF7L1	
ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS%REACTOME DATABASE ID RELEASE 74%9619229	Activation of RAC1 downstream of NMDARs	CAMK1	GIT1	CAMKK1	CAMKK2	RAC1	
SIGNALING BY ERBB2 IN CANCER%REACTOME DATABASE ID RELEASE 74%1227990	Signaling by ERBB2 in Cancer	ERBB2IP	EREG	SHC1	BTC	EGF	GAB1	NRG1	ERBB2	EGFR	NRG2	NRAS	HSP90AA1	CDC37	NRG3	PLCG1	SOS1	NRG4	HRAS	PIK3R1	PTPN12	PIK3CA	HBEGF	
DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15%REACTOME%R-HSA-3656243.1	Defective ST3GAL3 causes MCT12 and EIEE15	LUM	OGN	OMD	PRELP	KERA	FMOD	ST3GAL3	
SPHINGOLIPID METABOLISM%REACTOME DATABASE ID RELEASE 74%428157	Sphingolipid metabolism	GLB1	ESYT3	ESYT2	ESYT1	ENPP7	VAPA	CPTP	GALC	SPHK1	SMPD3	SMPD2	GM2A	GBA	HEXB	HEXA	PSAP	ARSB	GLB1L	SAMD8	PPM1L	PPAP2C	SGMS2	ALDH3B2	SGPL1	SPTLC1	SPTLC2	SPTLC3	ALDH3B1	ORMDL2	ORMDL3	OSBP	SPTSSB	UGT8	SPTSSA	KDSR	CERS3	CERS4	B3GALNT1	CERS5	CERS6	SPHK2	SPNS2	SMPD4	ORMDL1	SMPD1	SGPP2	SGPP1	ACER2	ACER1	FA2H	PRKD3	STS	ASAH2	VAPB	PPAP2B	ACER3	PPAP2A	ARSJ	PRKD2	ARSK	DEGS1	PRKD1	ARSH	ARSI	DEGS2	CSNK1G2	CERS1	ARSF	CERS2	ARSG	ARSD	ARSE	ARSA	SUMF2	GLA	SUMF1	GLTP	CERK	GBA2	NEU2	NEU3	UGCG	NEU1	B4GALNT1	ASAH1	CTSA	
BUTYROPHILIN (BTN) FAMILY INTERACTIONS%REACTOME DATABASE ID RELEASE 74%8851680	Butyrophilin (BTN) family interactions	BTN1A1	XDH	BTN3A1	BTN3A3	BTN3A2	BTN2A2	BTN2A1	BTNL9	BTNL8	PPL	CD209	BTNL2	
CLEAVAGE OF THE DAMAGED PYRIMIDINE%REACTOME%R-HSA-110329.2	Cleavage of the damaged pyrimidine	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST3H3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	OGG1	TINF2	TERF1	TERF2	NEIL3	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	NEIL2	NEIL1	TDG	MBD4	SMUG1	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	NTHL1	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
MITOPHAGY%REACTOME%R-HSA-5205647.4	Mitophagy	SQSTM1	MAP1LC3B	CSNK2A1	MAP1LC3A	FUNDC1	CSNK2A2	MTERF3	UBA52	TOMM70A	CSNK2B	TOMM7	TOMM5	TOMM6	UBB	ATG5	VDAC1	UBC	RPS27A	PINK1	ULK1	ATG12	PARK2	TOMM20	MFN1	MFN2	TOMM22	TOMM40	
DIGESTION AND ABSORPTION%REACTOME%R-HSA-8963743.2	Digestion and absorption	RSC1A1	SLC5A1	SLC2A5	SLC2A2	PNLIPRP1	GUCY2C	CHIA	MGAM	AMY2A	AMY1A	ALPI	AMY2B	TREH	AMY1B	AMY1C	GUCA2B	GUCA2A	LIPF	CHIT1	CLPS	SI	PIR	LCT	PNLIP	PNLIPRP3	
METABOLISM OF STEROIDS%REACTOME%R-HSA-8957322.2	Metabolism of steroids	IDI1	SEC23A	FDPS	MVK	CYP17A1	GGPS1	LRP2	IDI2	MSMO1	TGS1	PPAPDC2	HSD17B7	LSS	ACAT2	SEC24B	TM7SF2	SEC24A	SQLE	FABP6	ARV1	NSDHL	PMVK	STARD3	STARD4	STARD3NL	SEC24D	STARD6	SEC24C	STAR	CYP11A1	CARM1	TSPO	AKR1B1	TBL1X	GPAM	ABCC3	MED1	EBP	SC5D	DHCR24	DHCR7	CYP7B1	PPARA	SCD	STARD5	CH25H	HSD3B7	AKR1D1	AKR1C2	HSD17B1	OSBP	HSD11B1	HSD11B2	TBL1XR1	NFYA	NFYB	SERPINA6	NFYC	ELOVL6	AKR1C1	AKR1C4	GC	SLC27A5	INSIG2	INSIG1	OSBPL9	OSBPL7	OSBPL6	SRD5A2	SRD5A1	OSBPL3	ABCB11	OSBPL2	ACACA	HSD17B14	FDFT1	HSD17B12	PTGIS	HSD17B11	HMGCS1	FDX1	SCAP	MTF1	FDXR	SLC10A1	FDX1L	SLC10A2	CYP7A1	AKR1B15	NR1H4	AKR1C3	CYP8B1	HSD17B3	OSBPL1A	HSD17B2	LBR	SP1	BZRAP1	SLC27A2	ACOT8	HSD17B4	SUMO2	CYP46A1	PIAS4	CYP39A1	CYP27A1	LHB	CYP19A1	KPNB1	CYP27B1	CGA	CUBN	CYP11B2	CYP11B1	CYP2R1	CYP21A2	RAN	NCOA1	UBE2I	NCOA2	SAR1B	NCOA6	SMARCD3	SREBF2	RXRA	SLCO1B1	SLCO1B3	MBTPS1	ACACB	CYP51A1	ALB	SLCO1A2	MBTPS2	FASN	AMACR	MVD	POMC	VDR	CYP24A1	HELZ2	BAAT	ACOX2	LGMN	CHD9	CREBBP	HSD3B2	SRD5A3	HSD3B1	
TRIGLYCERIDE METABOLISM%REACTOME DATABASE ID RELEASE 74%8979227	Triglyceride metabolism	DGAT2	FABP4	DGAT1	AGMO	FABP9	ABHD5	FABP12	LIPE	GPD2	MGLL	FABP2	FABP3	FABP5	FABP6	PLIN3	PNPLA4	PNPLA5	PPP1CA	GK2	GK	GPAT2	PRKACG	PRKACB	PLIN1	PPP1CB	CAV1	GPAM	PRKACA	LPIN1	LPIN2	PPP1CC	LPIN3	FABP7	MOGAT3	MOGAT2	MOGAT1	FABP1	
RESISTANCE OF ERBB2 KD MUTANTS TO NERATINIB%REACTOME%R-HSA-9665246.1	Resistance of ERBB2 KD mutants to neratinib	ERBB2	HSP90AA1	CDC37	ERBB2IP	
REGULATED PROTEOLYSIS OF P75NTR%REACTOME DATABASE ID RELEASE 74%193692	Regulated proteolysis of p75NTR	NFKB1	PSEN2	NCSTN	RELA	APH1A	ADAM17	APH1B	NGFR	TRAF6	PSENEN	PSEN1	
ETHANOL OXIDATION%REACTOME DATABASE ID RELEASE 74%71384	Ethanol oxidation	ALDH1B1	ALDH1A1	ACSS1	ADH7	ADH5	ADH6	ALDH2	ADH1C	ADH1A	ADH4	ACSS2	ADH1B	
SCAVENGING BY CLASS F RECEPTORS%REACTOME DATABASE ID RELEASE 74%3000484	Scavenging by Class F Receptors	HYOU1	APOB	HSP90AA1	CALR	HSPH1	SCARF1	
NRAGE SIGNALS DEATH THROUGH JNK%REACTOME%R-HSA-193648.1	NRAGE signals death through JNK	ARHGEF26	MAGED1	ABR	BCL2L11	NGEF	ECT2	ARHGEF33	NGFR	ARHGEF35	ARHGEF37	ARHGEF39	ARHGEF38	NET1	ARHGEF10L	AATF	SOS1	AKAP13	MCF2L	ARHGEF10	PLEKHG2	MAPK8	TRIO	ARHGEF15	PLEKHG5	ARHGEF17	ARHGEF16	KALRN	ARHGEF19	ARHGEF18	NGF	ARHGEF9	ARHGEF3	ARHGEF4	RAC1	ARHGEF1	ARHGEF2	ARHGEF5	ARHGEF6	VAV1	FGD1	FGD2	GNA13	FGD3	FGD4	VAV3	SOS2	MCF2	VAV2	ARHGEF7	ARHGEF11	ARHGEF12	BAD	RASGRF2	TIAM1	PREX1	ARHGEF40	ITSN1	TIAM2	OBSCN	
ACTIVATION AND OLIGOMERIZATION OF BAK PROTEIN%REACTOME%R-HSA-111452.2	Activation and oligomerization of BAK protein	BID	BAK1	
NEURONAL SYSTEM%REACTOME DATABASE ID RELEASE 74%112316	Neuronal System	KCNA3	KCNA4	KCNA5	KCNA6	KCNA7	KCNJ1	KCNB1	KCNB2	SHARPIN	KCNJ14	KCNS1	KCNS2	KCNS3	SLC1A1	KCNK1	SLC1A2	KCNK2	KCNK3	HCN2	SLC1A6	KCNK4	SLC1A7	HCN1	SLC38A2	PRKAR2B	AKAP5	SLC32A1	MAPK1	ARHGEF9	GJA10	ABCC9	MAOA	KCNJ11	SIPA1L1	LRRTM3	SLC17A7	LRRTM4	LRRTM1	LRRTM2	HOMER3	DLGAP1	DLGAP3	DLGAP2	DLGAP4	IL1RAPL2	SHANK2	GLS	SHANK1	NLGN3	NLGN1	NLGN2	EPB41	STXBP1	NRXN3	NRXN2	BEGAIN	EPB41L5	SLITRK2	SLITRK1	EPB41L2	SLITRK4	EPB41L3	SLITRK3	SLITRK6	SLITRK5	PDLIM5	LRRC4B	NLGN4Y	KCNK13	NLGN4X	HOMER1	HOMER2	SYT7	PPFIBP1	PPFIBP2	SYT12	SYT10	APBA3	APBA2	SYT2	SYT1	SYT9	NRXN1	PANX1	GLS2	KCNQ2	KCNQ3	STX1A	SLC22A2	SLC22A1	SLC6A13	SLC6A12	SLC6A11	HSPA8	SLC6A1	SLC6A3	SLC18A2	GIT1	PTPRS	RTN3	SRC	PTPRF	NTRK3	LRFN3	PTPRD	LRFN2	LRFN4	LRFN1	PDPK1	CHAT	CHRNA1	KCNJ8	CHRNB2	ABCC8	CHRNA3	CHRNB4	PRKACG	CHRNB3	PRKACB	CHRNA2	GNGT1	CHRNA5	CHRNA4	CHRNA7	GNGT2	CHRNA6	ADCY9	CHRNA9	PRKAR1B	CHRND	CHRNG	DLG1	PRKAR1A	CHRNE	DLG3	ACTN2	PLCB3	DLG4	GRIK5	PLCB1	GRIK3	PLCB2	PRKAR2A	GRIK4	CAMK2A	GRIK1	GRIK2	PANX2	NCALD	ACHE	GNG3	GNG10	GNG2	GNG5	GNG4	GRIN2B	GNG7	GNG8	GRIN2D	ADCY4	ADCY3	ADCY2	ADCY1	ADCY8	ADCY7	NEFL	ADCY6	CREB1	ADCY5	GNG12	GNG11	GNG13	KIF17	GNB2	NRGN	PRKCG	CASK	GNB1	GRIA1	GRIA2	GNB4	LIN7A	GNB3	LIN7C	GNB5	PPM1E	LIN7B	PPM1F	CAMKK1	CAMKK2	GRIN2A	BCHE	LRRC7	GRIA3	GRIA4	GRIN2C	GRIN3B	GAD1	GRIN3A	GAD2	NBEA	CAMK4	APBA1	FLOT1	CAMK1	GRIN1	FLOT2	RAC1	DBNL	KCNJ2	KCNJ3	KCNJ4	GABBR2	KCNJ5	KCNJ6	GABBR1	KCNJ10	KCNJ12	KCNJ9	KCNJ15	KCNJ16	PRKAA1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	DLG2	PRKAB2	PRKAB1	RASGRF2	RASGRF1	GRM1	ABAT	ARL6IP5	GLUL	GRM5	UNC13B	CACNA2D3	CACNA2D2	GABRG3	GABRG2	SLC5A7	NRG1	EPB41L1	TSPAN7	GABRB3	GABRB2	GABRB1	SLC6A4	GABRR3	GABRR2	GABRR1	SYN3	SYN1	ALDH5A1	RPS6KA3	PICK1	CAMK2B	RPS6KA6	GLRA1	CAMK2D	RPS6KA2	GLRA2	CACNB1	RPS6KA1	GLRA3	CACNB2	GABRA2	CACNB3	MAPK3	GABRQ	CACNB4	GABRA1	GABRA6	CAMK2G	GABRA5	GABRA4	GABRA3	GRIP1	RIMS1	BZRAP1	MDM2	PPFIA1	PPFIA4	PPFIA3	PPFIA2	NAAA	CACNA1B	CACNA1A	CPLX1	NRAS	CACNA1E	GNAL	ALDH2	NPTN	GJC1	HRAS	HTR3E	HTR3C	HTR3D	HTR3A	SNAP25	HTR3B	GNAT3	AP2A1	LRTOMT	MYO6	DNAJC5	GLRB	KPNA2	PRKX	SLC18A3	GJD2	GNAI3	VAMP2	GNAI1	GNAI2	CACNG8	PRKCB	PRKCA	COMT	CACNG2	CACNG3	CACNG4	RAB3A	SLC1A3	IL1RAPL1	KCNG1	KCNG2	KCNG3	KCNG4	KCNH1	KCNH2	KCNH3	KCNH4	KCNH5	KCNH6	KCNK10	KCNH7	KCNH8	KCNK16	KCNK17	KCNK18	KCNQ1	KCNQ4	KCNQ5	KCNV1	KCNV2	KCNMB1	KCNMB2	KCNMB3	KCNN1	KCNMB4	KCNN2	KCNN3	PRKACA	KCNN4	KCNF1	KCNK6	KCNK7	KCNC1	KCNK9	KCNC2	KCNC3	KCNC4	KCND1	KCND2	KCND3	NSF	KCNAB1	KCNAB2	KCNAB3	KCNMA1	KCNA10	HCN4	SLC38A1	HCN3	KCNA1	KCNA2	
SIGNALING BY RHO GTPASES%REACTOME%R-HSA-194315.4	Signaling by Rho GTPases	DYNLL1	CKAP5	CFTR	MAPRE1	PAFAH1B1	DYNC1I2	CLASP1	DYNC1H1	NDE1	PLK1	VAV1	ARHGAP39	ARHGAP35	GDI1	GDI2	CTTN	RHOQ	TRIP10	BUB1B	CDC20	BUB3	MAD2L1	OCRL	CLASP2	NOX3	DAAM1	SCAI	PIN1	DIAPH3	RPS27	MKL1	FMNL3	FMNL1	FMNL2	YWHAB	XPO1	PRKCD	YWHAZ	CYFIP2	NCKAP1	CYFIP1	MAPK14	WIPF1	MAPK11	ARPC1B	WIPF2	ARPC1A	WIPF3	BRK1	WASL	ACTB	ACTG1	NCK1	ACTR3	VAV3	ACTR2	VAV2	BTK	WAS	NCKIPSD	NCKAP1L	WASF1	WASF2	WASF3	ARPC4	MYO9B	ARPC5	BAIAP2	ABI2	ARPC2	ARPC3	ABI1	NCF1	NCF2	NCF4	RAC2	CYBB	PIK3R4	ERCC6L	ZWILCH	IQGAP1	CASC5	KNTC1	MAD1L1	CDCA8	PTK2	PMF1	SKA1	SKA2	DSN1	RCC2	NDC80	ZWINT	AHCTF1	SGOL2	SGOL1	NUF2	SPDL1	NDEL1	NUDC	RANGAP1	INCENP	BIRC5	ITGB3BP	MIS12	CENPA	AURKB	NSL1	CENPC	LIN7B	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	CENPI	KLK3	TAOK1	KDM4C	CENPK	PKN1	CENPL	CENPM	CENPN	CENPO	B9D2	CENPP	CENPQ	SPC24	SPC25	ARHGAP10	PPP1CC	RASGRF2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	PIK3C3	CDKN1B	PRKCZ	CDC25C	KTN1	NUP107	PPP2R1B	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	PRKCB	HIST1H2AJ	PRKCA	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	NUP160	HIST1H3A	NUP85	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	S100A9	HIST1H3D	S100A8	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	KIF5B	KIF5A	AR	H3F3A	PREX1	H2BFS	HIST1H4A	ARHGDIA	HIST1H4B	ARHGEF40	ITSN1	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	TIAM2	HIST1H4E	HIST1H4F	HIST2H2AA3	OBSCN	HIST2H2AA4	DYNC1LI1	ARHGEF26	DYNC1LI2	HIST2H2AC	ABR	H2AFJ	ZW10	NGEF	ECT2	ARHGEF33	SEC13	ARHGEF35	NUP133	ARHGEF37	H2AFZ	ARHGEF39	H2AFX	ARHGEF38	H2AFV	HIST2H2BE	KLC1	NET1	HIST4H4	KLC4	KLC3	KLC2	ARHGEF10L	RACGAP1	HIST1H2BN	AKAP13	HIST1H2BM	MCF2L	HIST1H2BO	HIST1H2BJ	NF2	ARHGEF10	HIST1H2BI	PLEKHG2	HIST1H2BL	ARHGEF15	PLEKHG5	ARHGEF17	HIST1H2BK	PPP2CA	KIF18A	ARHGEF16	HIST2H4A	ARHGEF19	PPP2CB	ARHGEF18	HIST2H4B	MAPK1	NUP43	ARHGEF9	RANBP2	ARHGEF3	ARHGEF4	ARHGEF1	CLIP1	ARHGEF2	ARHGEF5	CTNNA1	IQGAP2	ARHGEF6	NUP37	IQGAP3	FGD1	MEN1	FGD2	GNA13	FGD3	FGD4	MCF2	DYNLL2	KIF2A	KIF2C	KIF2B	DYNC1I1	DIAPH1	CENPE	KIF14	CIT	PRC1	PPP1R12B	MYLK	KALRN	NCOA2	ARHGEF7	ROPN1	TAX1BP3	PKN3	GOPC	PKN2	RTKN	RHPN1	RHPN2	PPP1R14A	ITGB1	PDPK1	PIK3R2	DLG4	KDM1A	PAK1	PAK3	PAK2	ABL1	CTNNB1	TRIO	SRF	RAC1	CDC42	ARHGEF11	ARHGEF12	FLNA	ROCK1	ROCK2	LIMK2	LIMK1	RHOC	RHOA	MYL12B	RHOB	MYL6	MYH9	MYH14	MYH11	MYH10	MYL9	YWHAQ	SFN	YWHAH	CDH1	BCR	CFL1	KLK2	MAPK3	A2M	SRGAP3	SRGAP1	SOS1	NOX1	FAM13B	FAM13A	EVL	SOS2	ARHGDIG	ARHGAP36	SYDE2	ARHGAP44	SYDE1	NOXO1	ARHGAP42	OPHN1	ARHGAP40	ARHGDIB	RALBP1	STARD8	HMHA1	DEPDC1B	ARHGAP19	ARHGAP18	ARHGAP17	ARHGAP15	RHOBTB1	ARHGAP12	RHOBTB2	CYBA	ARHGAP22	INPP5B	ARHGAP21	ARHGAP20	RHOT2	RHOT1	STARD13	DVL1	DVL2	ARHGAP29	ARHGAP28	DVL3	ARHGAP27	ARHGAP26	NOXA1	ARHGAP25	ARHGAP24	ARHGAP23	ARHGAP33	ARHGAP32	ARHGAP31	ARHGAP30	ARHGAP11A	ARHGAP9	YWHAE	ARHGAP11B	TIAM1	ARHGAP8	ARHGAP1	ARHGAP5	PPP1CB	PFN1	ARHGAP6	ARHGAP4	PFN2	TAGAP	PPP2R1A	RAC3	RHOG	ARAP2	RHOH	ARAP3	ARAP1	RHOF	GMIP	RHOD	YWHAG	DEPDC7	RHOJ	RHOU	RHOV	CHN2	CHN1	PPP1R12A	MYO9A	DLC1	
DEFECTIVE SLC6A18 MAY CONFER SUSCEPTIBILITY TO IMINOGLYCINURIA AND OR HYPERGLYCINURIA%REACTOME DATABASE ID RELEASE 74%5659729	Defective SLC6A18 may confer susceptibility to iminoglycinuria and or hyperglycinuria	SLC6A18	
TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING%REACTOME%R-HSA-975110.2	TRAF6 mediated IRF7 activation in TLR7 8 or 9 signaling	IRAK4	MYD88	UBE2N	TRAF6	IRF7	IRAK1	TLR9	TLR7	UBE2V1	
CYTOSOLIC SENSORS OF PATHOGEN-ASSOCIATED DNA%REACTOME DATABASE ID RELEASE 74%1834949	Cytosolic sensors of pathogen-associated DNA	RIPK3	STAT6	ZBP1	TBK1	IRF3	TRIM56	NLRP4	DTX4	IRF7	UBA52	TLR3	RELA	CTNNB1	CRCP	TRIM32	UBB	XRCC6	XRCC5	TREX1	NLRC3	UBC	DDX41	IFI16	MB21D1	RPS27A	NFKB1	NFKBIA	POLR3GL	POLR3A	POLR3B	DHX9	POLR3C	MRE11A	NFKBIB	TRIM21	POLR3D	POLR3E	POLR1C	POLR3F	POLR3G	TMEM173	POLR3H	POLR3K	TICAM1	RIPK1	PRKDC	POLR2E	POLR2F	POLR2H	POLR2K	LRRFIP1	POLR2L	IKBKB	NFKB2	MYD88	DHX36	CREBBP	NKIRAS1	EP300	NKIRAS2	IKBKG	CHUK	
MET ACTIVATES PI3K AKT SIGNALING%REACTOME%R-HSA-8851907.1	MET activates PI3K AKT signaling	GAB1	PIK3R1	PIK3CA	HGF	MET	
NONSENSE MEDIATED DECAY (NMD) INDEPENDENT OF THE EXON JUNCTION COMPLEX (EJC)%REACTOME%R-HSA-975956.1	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	UBA52	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	PABPC1	RPS27L	RPS15A	RPL14	RPS3	GSPT2	RPS27A	RPL13	RPL15	GSPT1	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	EIF4G1	RPL22L1	UPF1	FAU	RPL26L1	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	NCBP1	RPS18	NCBP2	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	ETF1	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	
INTERCONVERSION OF POLYAMINES%REACTOME DATABASE ID RELEASE 74%351200	Interconversion of polyamines	SAT1	PAOX	
CDK-MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6%REACTOME DATABASE ID RELEASE 74%69017	CDK-mediated phosphorylation and removal of Cdc6	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	CCNE2	CCNE1	PSMB10	PSMA7	ANAPC4	PSMA8	ANAPC5	PSMB6	PSMB7	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	FZR1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	CDC6	PSMC2	UBE2S	CDC16	CDK2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
GOLGI-TO-ER RETROGRADE TRANSPORT%REACTOME DATABASE ID RELEASE 74%8856688	Golgi-to-ER retrograde transport	RINT1	DYNC1LI1	DYNLL1	DYNC1LI2	KIF16B	PLA2G4A	ZW10	KDELR2	KIF20A	KDELR3	KIF20B	COPB2	COPA	TMED10	COPB1	PAFAH1B1	DYNC1I2	KLC1	DCTN2	KLC4	DCTN3	AGPAT3	KLC3	KLC2	KIF3B	RACGAP1	RAB1A	KIF3C	RAB6A	RAB6B	SURF4	RAB1B	KIF18A	KIF18B	KIF4B	KIF4A	DYNC1H1	COPE	ARF3	ARF4	ARF1	KIF11	BICD1	USE1	BICD2	KIF15	KIF19	CAPZB	KIF13B	TMED3	KIF1C	TMED2	KIF1B	KIF1A	TMED7	TMED9	KIF25	COPZ2	KIF23	KIF22	ARFGAP3	KIF6	DYNLL2	ARFGAP1	KIF27	COPZ1	ARFGAP2	KIF9	KIFC2	KIF2A	KIFC1	KIF2C	KIF2B	SEC22B	PAFAH1B3	ARF5	PAFAH1B2	DCTN6	NAPA	DCTN5	NAPB	NBAS	DCTN1	DCTN4	STX18	NAPG	BNIP1	DYNC1I1	GALNT2	GALNT1	GBF1	ARCN1	CENPE	CAPZA3	KIF26A	CAPZA1	KIF26B	CAPZA2	RAB18	RAB3GAP2	COPG2	COPG1	ACTR10	RAB3GAP1	PLA2G6	ACTR1A	KDELR1	KIF3A	KIF5B	KIF5A	KIF21A	KIF21B	KIFAP3	NSF	
CAM PATHWAY%REACTOME%R-HSA-111997.1	CaM pathway	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	CAMK2G	CREB1	ADCY5	PRKCA	PRKCG	PDE1C	PDE1B	PDE1A	ADRBK1	CAMKK1	PRKCD	CAMKK2	PRKAR2B	PRKACG	PRKACB	KPNA2	NBEA	CAMK4	ADCY9	PRKAR1B	PRKAR1A	PRKX	CAMK2A	PRKAR2A	PRKACA	CAMK2B	ADCY4	CAMK2D	ADCY3	
REGULATION OF PYRUVATE DEHYDROGENASE (PDH) COMPLEX%REACTOME DATABASE ID RELEASE 74%204174	Regulation of pyruvate dehydrogenase (PDH) complex	PDHB	RXRA	PPARD	PDHA2	PDHA1	DLAT	GSTZ1	DLD	PDPR	PDK4	PDK3	PDK2	PDK1	PDP1	PDP2	PDHX	
SIGNALING BY ERBB2 ECD MUTANTS%REACTOME%R-HSA-9665348.2	Signaling by ERBB2 ECD mutants	ERBB2IP	SHC1	EGF	GAB1	ERBB2	EGFR	NRAS	HSP90AA1	CDC37	PLCG1	SOS1	HRAS	PIK3R1	PIK3CA	
P38MAPK EVENTS%REACTOME%R-HSA-171007.3	p38MAPK events	RALA	RALB	NRAS	RALGDS	MAPKAPK3	HRAS	MAPK12	MAPKAPK2	MAPK14	MAPK13	MAPK11	
MITOTIC ANAPHASE%REACTOME DATABASE ID RELEASE 74%68882	Mitotic Anaphase	DYNC1LI1	DYNLL1	DYNC1LI2	LMNB1	CKAP5	TUBA4A	ZW10	NUP62	UBE2D1	CDC23	EMD	CDC26	NDC1	MAPRE1	CDC27	SEC13	NUP133	UBA52	ANAPC7	UBE2E1	PAFAH1B1	DYNC1I2	ANAPC4	ANAPC5	CCNB2	NUP54	CCNB1	TUBA4B	ANAPC1	UBB	ANAPC2	ANAPC15	ANAPC16	UBC	ANAPC10	ANAPC11	RPS27A	TUBAL3	PPP2CA	KIF18A	CLASP1	PPP2CB	DYNC1H1	UBE2C	NUP43	RANBP2	NDE1	UBE2S	PLK1	CDC16	TUBB4B	TUBA8	TUBB4A	NUP35	CLIP1	CDK1	NUP37	TUBB8P12	TUBB8	TUBA3E	TUBA1C	DYNLL2	TUBB6	TUBA1B	TUBB3	TUBB1	ANKLE2	PPP2R2A	SIRT2	KIF2A	TUBB2B	KIF2C	TUBB2A	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	CLASP2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	DYNC1I1	PSMD2	PSMD3	PSMD1	PSMA5	CENPE	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	RPS27	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	RCC1	PSMA7	XPO1	PSMA8	PSMB6	TNPO1	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	IST1	SPAST	CC2D1B	SUMO1	UBE2I	ERCC6L	ZWILCH	CASC5	SMC3	KNTC1	MAD1L1	CDCA5	CDCA8	PDS5B	PDS5A	PMF1	VPS4A	SKA1	SKA2	DSN1	RAD21	RCC2	NDC80	ZWINT	STAG1	STAG2	AHCTF1	SGOL2	CHMP2B	SGOL1	NUF2	CHMP2A	CHMP4C	WAPAL	CHMP4B	SPDL1	NDEL1	NUDC	CHMP3	CHMP4A	RANGAP1	SMC1A	CHMP6	INCENP	CHMP7	BIRC5	ITGB3BP	MIS12	CENPA	AURKB	NSL1	CENPC	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	CENPN	CENPO	B9D2	CENPP	CENPQ	SPC24	SPC25	PPP1CC	PTTG1	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	LBR	KPNB1	RAN	NUP107	NUP188	PPP2R1B	BANF1	VRK1	LEMD3	LEMD2	NUP93	ESPL1	NUP205	POM121	NUP160	NUP85	TUBA1A	PPP2R1A	NUP155	
SIGNALING BY KIT IN DISEASE%REACTOME%R-HSA-9669938.2	Signaling by KIT in disease	FYN	STAT5A	STAT5B	YES1	STAT1	STAT3	NRAS	LYN	JAK2	SOS1	PIK3R3	HRAS	PIK3R2	PIK3R1	PIK3CA	LCK	KIT	
DEFECTIVE CYP2R1 CAUSES RICKETS VITAMIN D-DEPENDENT 1B (VDDR1B)%REACTOME%R-HSA-5579027.2	Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B)	CYP2R1	
DEFECTIVE PRO-SFTPC CAUSES SMDP2 AND RDS%REACTOME DATABASE ID RELEASE 74%5688354	Defective pro-SFTPC causes SMDP2 and RDS	SFTPC	
FATTY ACID METABOLISM%REACTOME DATABASE ID RELEASE 74%8978868	Fatty acid metabolism	LTA4H	CYP2C9	CYP2C8	PLA2G4A	CYP1A2	HADHB	CYP1A1	HADHA	NUDT7	CRAT	SCD5	PPARD	ABCD1	ABCC1	ACADL	ECI1	DECR1	ELOVL1	FADS2	SCD	SCP2	ELOVL5	ACOT9	ELOVL2	ELOVL3	ACOT7	ACOT1	HACD1	HACD3	HACD2	HACD4	PTGS2	MCAT	TBXAS1	PPT1	PPT2	PRKAA2	ELOVL4	PRKAG2	ELOVL6	ELOVL7	ACSBG1	ACSBG2	PRKAB2	SLC27A3	ECHS1	ACSM3	ACSM6	THEM5	HADH	ACADS	FADS1	CPT1A	ACSL1	FAAH	TECRL	ACACA	SLC25A1	CYP4A22	HPGDS	PTGDS	CBR1	HSD17B12	PTGIS	FAAH2	PCCA	PTGR1	PCCB	CPT2	PTGR2	ACAD11	PTGES	ACAD10	ALOX12B	ACSL6	CYP4F22	ACADM	ACSL5	PTGS1	CYP4A11	FAM213B	AWAT1	ALOXE3	PTGES2	EPHX2	CYP4F2	ACLY	CYP4F3	AKR1C3	MCEE	CYP4B1	CYP4F11	ACADVL	CYP4F8	TECR	CYP8B1	ALOX15B	HSD17B3	ALOX15	ALOX12	HSD17B8	CBR4	CYP1B1	OLAH	ACAA2	SLC22A5	MID1IP1	PECR	ACOT11	THRSP	PHYH	ACOT12	SLC25A20	ACOT13	CPT1B	SLC25A17	HACL1	SLC27A2	MORC2	ACBD7	ACBD6	GPX2	ACBD4	ACOT8	ACSF3	ACSF2	EHHADH	DBI	HSD17B4	DECR2	ACOT6	ACAA1	ACOT4	CYP2U1	MAPKAPK2	NDUFAB1	ACOXL	NUDT19	RXRA	ACSL4	ACSL3	GGT1	ACOT2	DPEP2	DPEP1	DPEP3	PTGES3	MECR	HAO2	GGT5	ACBD5	MMAA	FASN	MUT	PON3	GPX1	THEM4	AMACR	GPX4	PON2	ALOX5AP	PON1	LTC4S	CROT	CYP2C19	ACOX2	PCTP	ACOX3	CYP2J2	HPGD	ALOX5	
PARASITE INFECTION%REACTOME DATABASE ID RELEASE 74%9664407	Parasite infection	MAPK3	IGKV2-28	IGKV1-12	IGKV3D-20	IGKV2D-28	ABL1	IGKV4-1	IGKV2D-30	IGKV3-11	LYN	IGKV5-2	HCK	MAPK1	CD3G	CYFIP2	NCKAP1	FCGR3A	CYFIP1	RAC1	WIPF1	YES1	ARPC1B	FGR	WIPF2	ARPC1A	VAV1	WIPF3	BRK1	WASL	ACTB	DOCK1	ACTG1	NCK1	ACTR3	VAV3	ACTR2	CDC42	VAV2	MYH2	ELMO1	BTK	ELMO2	WAS	NCKIPSD	NCKAP1L	WASF1	WASF2	WASF3	MYO10	MYO5A	ARPC4	MYO9B	ARPC5	BAIAP2	MYO1C	ABI2	ARPC2	ARPC3	ABI1	MYH9	IGHG4	IGHG1	IGHG2	SYK	CRK	FYN	PTK2	
MPS VII - SLY SYNDROME%REACTOME DATABASE ID RELEASE 74%2206292	MPS VII - Sly syndrome	GUSB	
NON-CODING RNA METABOLISM%REACTOME DATABASE ID RELEASE 74%194441	Non-coding RNA Metabolism	NUP62	NDC1	SEC13	TGS1	NUP133	NUP50	NUP54	SNRPD2	SNRPD1	SNRPD3	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	NUP107	NUP188	NUP214	NUP210	NUP93	NUP205	POM121	AAAS	SNRPG	NUP160	PRMT5	NCBP1	NUP85	NCBP2	SNRPE	TPR	SNRPF	NUP88	SNRPB	NUP155	GEMIN2	PHAX	WDR77	NUP153	CLNS1A	GEMIN4	GEMIN5	GEMIN6	GEMIN7	GEMIN8	DDX20	SMN2	SMN1	SNUPN	
NS1 MEDIATED EFFECTS ON HOST PATHWAYS%REACTOME DATABASE ID RELEASE 74%168276	NS1 Mediated Effects on Host Pathways	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	AAAS	NUP160	KPNA7	KPNA4	NUP85	KPNA5	TPR	KPNA2	KPNA3	KPNA1	NUP88	KPNB1	CPSF4	NUP43	EIF2AK2	RAE1	ISG15	RANBP2	NUP155	NUP35	NUPL2	NUP37	PABPN1	NUP107	NUP153	NUP188	
MITOCHONDRIAL FATTY ACID BETA-OXIDATION OF SATURATED FATTY ACIDS%REACTOME%R-HSA-77286.2	mitochondrial fatty acid beta-oxidation of saturated fatty acids	ACADL	MECR	HADHB	HADHA	ACADVL	ECHS1	ACSM3	ACSM6	HADH	ACADS	ACADM	
MAP2K AND MAPK ACTIVATION%REACTOME DATABASE ID RELEASE 74%5674135	MAP2K and MAPK activation	MAPK3	RAF1	CSK	SRC	RAP1B	RAP1A	MARK3	IL17RD	YWHAB	NRAS	FN1	CNKSR2	HRAS	APBB1IP	CNKSR1	ITGB3	ARRB1	ARAF	ARRB2	LAMTOR2	WDR83	MAPK1	FGB	FGA	LAMTOR3	ITGA2B	VWF	PEBP1	KSR1	FGG	TLN1	KSR2	IQGAP1	BRAF	MAP2K1	MAP2K2	VCL	
PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS%REACTOME%R-HSA-202427.6	Phosphorylation of CD3 and TCR zeta chains	HLA-DQA1	TRAV19	HLA-DRB5	CSK	HLA-DRB4	PTPRJ	CD4	HLA-DPB1	PTPRC	HLA-DRA	HLA-DRB3	HLA-DRB1	CD3G	CD3E	CD3D	HLA-DPA1	HLA-DQB2	HLA-DQB1	LCK	PAG1	PTPN22	HLA-DQA2	
E2F-ENABLED INHIBITION OF PRE-REPLICATION COMPLEX FORMATION%REACTOME%R-HSA-113507.3	E2F-enabled inhibition of pre-replication complex formation	ORC4	ORC6	ORC1	ORC3	ORC2	MCM8	CCNB1	ORC5	CDK1	
NUCLEAR PORE COMPLEX (NPC) DISASSEMBLY%REACTOME DATABASE ID RELEASE 74%3301854	Nuclear Pore Complex (NPC) Disassembly	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	CCNB2	NUP54	POM121	CCNB1	AAAS	NUP160	NUP85	TPR	NUP88	NUP43	RAE1	RANBP2	NEK9	NUP155	NUP35	NUPL2	NEK6	CDK1	NUP37	NEK7	NUP107	NUP153	NUP188	
INTEGRATION OF ENERGY METABOLISM%REACTOME%R-HSA-163685.1	Integration of energy metabolism	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY5	GNG12	KCNB1	GNG11	GNG13	KCNS3	GNB2	GNB1	AGPAT1	GNB4	GNB3	GNB5	PRKAR2B	AKAP5	PPP2CA	PPP2CB	KCNJ11	PFKFB1	ADIPOQ	FFAR1	STXBP1	RAP1A	PRKAA2	GLP1R	TALDO1	PRKAG2	TKT	STK11	PRKAB2	MLXIPL	CYSLTR2	RAPGEF3	RAPGEF4	SLC2A2	ACACA	CACNA2D2	PPP2R5D	ACLY	ADIPOR1	ADIPOR2	CACNB2	CACNB3	GCG	CACNA1A	CHRM3	CACNA1E	STX1A	SNAP25	SLC2A1	AHCYL1	SYT5	MLX	ADRA2C	MARCKS	ADRA2A	PPP2R1B	VAMP2	GNAI1	GNAI2	PRKCA	ACSL4	ACSL3	ACACB	INS	GNA14	GNA15	KCNG2	GNA11	GNAQ	ABCC8	FASN	PRKACG	PRKACB	GNGT1	GNGT2	ADCY9	CACNA1D	PRKAR1B	CACNA1C	PPP2R1A	PRKAR1A	PLCB3	PLCB1	PLCB2	PRKACA	PRKAR2A	ITPR1	ITPR2	ITPR3	GNAS	KCNC2	GNG3	IQGAP1	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	CD36	ADCY4	ADCY3	
PROLONGED ERK ACTIVATION EVENTS%REACTOME DATABASE ID RELEASE 74%169893	Prolonged ERK activation events	MAPK3	KIDINS220	NGF	MAPK1	RAP1A	FRS2	YWHAB	CRKL	RAPGEF1	NTRK1	BRAF	MAP2K1	MAP2K2	CRK	
CREB3 FACTORS ACTIVATE GENES%REACTOME DATABASE ID RELEASE 74%8874211	CREB3 factors activate genes	CREB3L2	MBTPS2	CREB3L3	MBTPS1	CREB3	DCSTAMP	CREB3L4	CREBRF	CREB3L1	
FC EPSILON RECEPTOR (FCERI) SIGNALING%REACTOME DATABASE ID RELEASE 74%2454202	Fc epsilon receptor (FCERI) signaling	LAT2	PAK2	FOS	NFATC1	UBE2D1	UBA52	GAB2	CUL1	UBB	UBC	MAPK9	MAPK8	RPS27A	MAP3K1	MAPK10	MAPK1	RAC1	PIK3CB	VAV1	PLCG2	NFATC3	NFATC2	SYK	GRAP2	LCP2	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	PSMA6	PSMA3	MAPK3	PSMA4	PSMA1	PSMA2	UBE2D2	PSME3	PSME4	IGKV2-28	IGKV1-12	PSME1	PSME2	IGKV3D-20	CDC34	CARD11	IGKV2D-28	PSMD10	TRAF6	PSMB11	IGKV4-1	PSMD12	PSMD11	IGHE	PRKCQ	PSMD14	UBE2V1	PSMD13	IGKV2D-30	BCL10	RASGRP2	PSMB10	RASGRP1	MALT1	RASGRP4	PSMA7	NRAS	IGKV3-11	RELA	PLCG1	LYN	PSMA8	SOS1	PSMB6	IGKV5-2	UBE2N	HRAS	PSMB7	TAB3	PSMB4	TAB2	PSMB5	TAB1	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	AHCYL1	PSMC2	FCER1A	VAV3	VAV2	BTK	FCER1G	PDPK1	MS4A2	PIK3R2	PIK3R1	PIK3CA	MAP2K4	PPP3CA	PPP3CB	FYN	BTRC	ITPR1	ITPR2	MAP2K7	ITPR3	JUN	SKP1	PPP3R1	FBXW11	ITK	TXK	TEC	PAK1	
GLUCAGON SIGNALING IN METABOLIC REGULATION%REACTOME%R-HSA-163359.2	Glucagon signaling in metabolic regulation	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY5	GNG12	GNG11	GNG13	GCG	GNB2	GNB1	GNB4	GNB3	CYSLTR2	PRKAR2B	PRKACG	PRKACB	ADCY9	PRKAR1B	PRKAR1A	PRKAR2A	PRKACA	GNAS	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	ADCY4	ADCY3	
SYNTHESIS OF CL%REACTOME DATABASE ID RELEASE 74%1483076	Synthesis of CL	CRLS1	
SLC TRANSPORTER DISORDERS%REACTOME%R-HSA-5619102.6	SLC transporter disorders	SLC34A1	AVPR1B	AVPR1A	NUP62	SLC9A6	SLC22A5	NDC1	SLC9A9	SEC13	SLC26A2	NUP133	SLC1A1	NUP50	SLC5A5	NUP54	CP	SLC5A1	SLC26A4	SLC26A3	SLC6A19	SLC6A18	SLC2A1	SLC36A2	SLC6A14	NUP43	RAE1	SLC7A7	RANBP2	SLC6A2	NUP35	SLC6A3	SLC24A1	SLC24A4	SLC6A5	NUPL2	NUP37	SLC20A2	NUP107	NUP188	SLC3A2	HK1	SLC27A4	SLC17A8	NUP214	NUP210	SLCO1B1	SLCO1B3	SLC24A5	SLC22A18	NUP93	SLC35A2	SLC35A1	SLC35A3	SLC33A1	SLC35C1	SLC1A3	SLC6A20	SLC34A2	SLCO2A1	AVP	SLC12A3	SLC7A9	NUP205	POM121	SLC3A1	SLC12A1	SLC12A6	SLC29A3	AAAS	SLC39A4	NUP160	SLC5A2	SLC2A10	AVPR2	NUP85	TPR	SLC2A2	SLC16A1	RHAG	NUP88	BSG	GCKR	NUP155	GCK	SLC40A1	HEPH	SLC5A7	SLC17A5	SLC22A12	NUP153	SLC4A1	SLC2A9	SLC4A4	SLC11A2	SLC34A3	
NOTCH-HLH TRANSCRIPTION PATHWAY%REACTOME%R-HSA-350054.3	Notch-HLH transcription pathway	NOTCH3	NOTCH4	HDAC6	TBL1XR1	MAML3	MAMLD1	HDAC4	HDAC5	NOTCH1	HDAC8	HDAC9	HDAC7	NCOR2	NCOR1	HDAC10	HDAC11	TBL1X	SNW1	NOTCH2	MAML2	MAML1	KAT2B	RBPJ	KAT2A	HDAC2	HDAC1	CREBBP	HDAC3	
MITOCHONDRIAL TRANSLATION%REACTOME DATABASE ID RELEASE 74%5368287	Mitochondrial translation	ICT1	GADD45GIP1	PTCD3	MRPL27	MRPL28	ERAL1	MRPL23	MRPL24	MRPL21	MRPL22	MRPL30	MRPS17	MTFMT	MRPS15	MRPS16	MRPS14	MRPS11	MRPS12	MRPL38	MRPL39	MRPS10	MRPL36	MRPL37	MRPL34	MRPL35	MRPL32	MRPL33	MRPL41	MRPL4	MRPL42	MRPL3	MRPL2	MRPL1	MRPL40	MRPL9	CHCHD1	MRPS28	MRPS26	MRPS27	MRPS24	GFM1	GFM2	MRPS25	TSFM	MRPS22	MTRF1L	MRPS23	TUFM	MRRF	MRPL49	MRPS18B	MRPS2	MRPS18A	MRPL47	MRPL48	MRPS7	MRPL45	MRPS6	MRPL46	MRPL43	MRPS5	MRPS18C	MRPL44	MRPL52	OXA1L	MRPL53	MRPL50	MRPS9	MRPL51	AURKAIP1	DAP3	MRPS35	MRPS36	MRPL18	MRPS33	MRPS34	MRPL19	MRPL16	MRPS31	MRPL17	MTIF2	MRPL14	MRPS30	MTIF3	MRPL15	MRPL12	MRPL13	MRPL57	MRPL10	MRPL54	MRPL11	MRPL55	MRPL20	
CRNA SYNTHESIS%REACTOME DATABASE ID RELEASE 74%192869	cRNA Synthesis	
ZINC TRANSPORTERS%REACTOME%R-HSA-435354.1	Zinc transporters	SLC39A6	SLC39A5	SLC39A8	SLC39A7	SLC39A2	SLC39A1	SLC39A3	SLC30A3	SLC30A7	SLC30A2	SLC30A6	SLC30A8	SLC30A1	SLC30A5	SLC39A10	SLC39A4	SLC39A14	
PLC-GAMMA1 SIGNALLING%REACTOME DATABASE ID RELEASE 74%167021	PLC-gamma1 signalling	PLCG1	NGF	NTRK1	
DNA REPLICATION PRE-INITIATION%REACTOME DATABASE ID RELEASE 74%69002	DNA Replication Pre-Initiation	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	MCM7	PSME3	MCM8	PSME4	PSME1	PSME2	PSMD10	PSMB11	CDC7	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	MCM3	MCM4	PSMA7	MCM5	PSMA8	PSMB6	MCM6	PSMB7	PSMB4	UBB	MCM2	PSMB5	PSMB2	PSMB3	UBC	PSMB1	E2F2	PSMF1	SHFM1	ORC5	PSMB8	ORC4	RPS27A	PSMB9	ORC6	ORC1	PSMC5	ORC3	PSMC6	ORC2	PSMC3	CDT1	PSMC4	PSMC1	CDC6	PSMC2	RPA1	RPA2	CDK2	RPA3	PRIM2	PRIM1	POLA1	POLA2	E2F3	GMNN	MCM10	DBF4	RPA4	POLE4	PSMD8	POLE2	PSMD9	CDC45	PSMD6	POLE3	PSMD7	PSMD4	POLE	PSMD5	PSMD2	PSMD3	PSMD1	E2F1	PSMA5	
NEGATIVE REGULATION OF FGFR3 SIGNALING%REACTOME%R-HSA-5654732.1	Negative regulation of FGFR3 signaling	RPS27A	MAPK3	PPP2CA	PPP2CB	PTPN11	MAPK1	PPP2R1A	FRS2	FGF20	UBA52	FGF1	FGF23	FGF2	FGF4	CBL	FGF16	FGF9	MKNK1	BRAF	UBB	FGF18	SPRY2	UBC	
RRNA PROCESSING%REACTOME DATABASE ID RELEASE 74%72312	rRNA processing	CSNK1E	NOP2	ISG20L2	EMG1	UTP20	NOP14	RPP40	RCL1	NOP10	RBM28	DDX49	DDX47	WDR3	UBA52	NOB1	PELP1	UTP15	DDX52	SENP3	UTP18	C1D	SKIV2L2	DDX21	BMS1	RPP14	DCAF13	NOP56	NOP58	KRR1	RPS27A	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	TRMT10C	RPS27	NSUN4	RPS29	RNMTL1	RPL27A	ELAC2	MTERF4	RPS20	RPS21	TFB1M	RPS24	FTSJ2	KIAA0391	RPS23	RPLP1	HSD17B10	RPLP0	MRM1	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	DIS3	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	EXOSC7	RPL13	EXOSC6	RPL15	EXOSC5	RPS2	EXOSC4	RPL18	EXOSC9	RPL17	EXOSC8	EXOSC3	EXOSC2	RPL19	EXOSC1	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	LTV1	RRP1	FCF1	THUMPD1	PWP2	RRP9	IMP3	WDR75	IMP4	CIRH1A	XRN2	RRP7A	PDCD11	ERI1	GAR1	WBSCR22	DHX37	PNO1	TBL3	LAS1L	MPHOSPH10	NOL11	NOL12	NAT10	WDR46	WDR43	TRMT112	RIOK2	RIOK1	UTP14A	UTP14C	WDR36	TEX10	DIEXF	GNL3	NHP2L1	NIP7	TSR3	HEATR1	NOL9	NOC4L	NOL6	EXOSC10	PES1	RRP36	UTP6	RIOK3	UTP3	WDR18	WDR12	BYSL	BOP1	TSR1	MPHOSPH6	RPP30	FBL	RPP38	DIMT1	UTP11L	FTSJ3	EBNA1BP2	DKC1	NCL	CSNK1D	NHP2	RPP21	RPP25	
CALCINEURIN ACTIVATES NFAT%REACTOME%R-HSA-2025928.2	Calcineurin activates NFAT	PPP3CA	PPP3CB	PPP3R1	NFATC1	PPIA	NFATC3	NFATC2	FKBP1A	
VRNA SYNTHESIS%REACTOME%R-HSA-192814.3	vRNA Synthesis	PARP1	
DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1%REACTOME%R-HSA-110357.1	Displacement of DNA glycosylase by APEX1	MPG	OGG1	APEX1	TDG	MBD4	SMUG1	NTHL1	
TGFBR2 MSI FRAMESHIFT MUTANTS IN CANCER%REACTOME DATABASE ID RELEASE 74%3642279	TGFBR2 MSI Frameshift Mutants in Cancer	TGFB1	TGFBR2	
EGFR TRANSACTIVATION BY GASTRIN%REACTOME%R-HSA-2179392.1	EGFR Transactivation by Gastrin	EGFR	NRAS	PRKCA	SOS1	HRAS	MMP3	HBEGF	
LYSOSPHINGOLIPID AND LPA RECEPTORS%REACTOME%R-HSA-419408.3	Lysosphingolipid and LPA receptors	LPAR5	LPAR1	S1PR3	S1PR2	S1PR1	LPAR2	LPAR3	S1PR5	S1PR4	
DEFECTIVE BASE EXCISION REPAIR ASSOCIATED WITH NEIL1%REACTOME%R-HSA-9616334.2	Defective Base Excision Repair Associated with NEIL1	NEIL1	
ACYL CHAIN REMODELING OF CL%REACTOME%R-HSA-1482798.2	Acyl chain remodeling of CL	PLA2G4A	HADHB	HADHA	TAZ	LCLAT1	PLA2G6	
ACETYLCHOLINE REGULATES INSULIN SECRETION%REACTOME DATABASE ID RELEASE 74%399997	Acetylcholine regulates insulin secretion	GNA11	CHRM3	GNAQ	MARCKS	PRKCA	PLCB3	PLCB1	PLCB2	GNA14	GNA15	
DEFECTIVE MPDU1 CAUSES MPDU1-CDG (CDG-1F)%REACTOME%R-HSA-4687000.2	Defective MPDU1 causes MPDU1-CDG (CDG-1f)	MPDU1	
DEFECTIVE BTD CAUSES BIOTIDINASE DEFICIENCY%REACTOME%R-HSA-3371598.1	Defective BTD causes biotidinase deficiency	BTD	
ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS%REACTOME DATABASE ID RELEASE 74%380994	ATF4 activates genes in response to endoplasmic reticulum stress	CEBPB	CXCL8	CEBPG	HERPUD1	CCL2	IGFBP1	NFYA	NFYB	NFYC	ASNS	DDIT3	ATF6	ATF3	ATF4	KHSRP	DIS3	DCP2	PARN	EXOSC7	EXOSC6	EXOSC5	EXOSC4	EXOSC9	EXOSC8	EXOSC3	EXOSC2	EXOSC1	
DEFECTIVE SLC39A4 CAUSES ACRODERMATITIS ENTEROPATHICA, ZINC-DEFICIENCY TYPE (AEZ)%REACTOME%R-HSA-5619088.2	Defective SLC39A4 causes acrodermatitis enteropathica, zinc-deficiency type (AEZ)	SLC39A4	
RNA POLYMERASE II TRANSCRIBES SNRNA GENES%REACTOME DATABASE ID RELEASE 74%6807505	RNA polymerase II transcribes snRNA genes	TAF11	TAF6	TAF5	SP1	ELL	CCNT1	SNAPC5	SUPT4H1	SNAPC1	SNAPC2	SNAPC3	SNAPC4	ZNF143	POU2F1	PCF11	TBP	GTF2F1	GTF2F2	SUPT5H	CDK9	CCNK	SRRT	INTS1	INTS3	INTS2	INTS5	INTS4	INTS7	INTS6	INTS9	INTS8	INTS12	INTS10	ICE1	ICE2	POLR2A	SSU72	POLR2B	POLR2C	NABP2	NABP1	NCBP1	POLR2D	TAF8	NCBP2	ELL2	POLR2E	ELL3	ZC3H8	POLR2F	RPRD2	RPAP2	POLR2G	ASUN	POLR2H	VWA9	POLR2I	CPSF3L	POLR2J	RPRD1B	RPRD1A	POLR2K	POLR2L	POU2F2	CCNT2	PHAX	GTF2A1	CDK7	GTF2A2	GTF2B	TAF9	AK6	GTF2E1	GTF2E2	TAF13	
ROBO RECEPTORS BIND AKAP5%REACTOME DATABASE ID RELEASE 74%9010642	ROBO receptors bind AKAP5	PPP3CB	PRKCA	PRKAR2A	PRKACA	PRKACG	AKAP5	ROBO2	PRKACB	
JOSEPHIN DOMAIN DUBS%REACTOME%R-HSA-5689877.2	Josephin domain DUBs	RPS27A	JOSD2	ATXN3	JOSD1	RAD23A	RAD23B	ATXN3L	UBB	PARK2	VCP	UBC	UBA52	
MAPK FAMILY SIGNALING CASCADES%REACTOME DATABASE ID RELEASE 74%5683057	MAPK family signaling cascades	UBA52	UBB	UBC	RPS27A	PPP2CA	PPP2CB	MAPK1	IRS2	PIK3CB	CDK1	JAK2	IL6	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	MAPKAPK5	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PRKCQ	PSMD14	PSMD13	YWHAB	PSMB10	RASGRP1	HSPB1	PSMA7	RASGRP4	XPO1	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	KALRN	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	NCOA3	IRS1	SRC	DNAJB1	IGF2BP1	CCND3	IL6R	FN1	PIK3R2	PIK3R1	PIK3CA	PRKACG	PRKACB	RBX1	ARAF	WDR83	PRKG2	FYN	SYNGAP1	DLG1	GOLGA7	DLG3	ACTN2	DLG4	PAQR3	FLT3LG	FRS2	CAMK2A	FRS3	EREG	BTC	TLN1	PDGFB	TGFA	IQGAP1	RCE1	RALGDS	BRAP	ICMT	BRAF	GRIN2B	PTK2	GRIN2D	PPP5C	ARTN	PAK1	RGL3	RGL1	RGL2	PAK3	RET	RAF1	AREG	PAK2	PEA15	NEFL	JAK3	JAK1	FOXO1	DUSP4	DUSP5	LYPLA1	DUSP2	TNRC6C	MOV10	DUSP1	AGO3	GFRA1	AGO4	DUSP8	AGO1	GFRA3	IL17RD	AGO2	DUSP9	GFRA2	DUSP6	DUSP7	GFRA4	CNKSR2	TNRC6A	APBB1IP	TNRC6B	CNKSR1	MRAS	LRRC7	KIT	RAPGEF2	HBEGF	RAG2	SHOC2	RAG1	DAB2IP	RANBP9	USP17L2	MYC	GRIN1	EPGN	FOXO3	ZDHHC9	KBTBD7	KLB	CSF2	ITGA2B	PEBP1	RAC1	IL5RA	FGF1	FGF2	FGF3	FGF4	PPP1CC	FGF6	FGF7	FNTA	FGF9	FNTB	NRTN	PDGFRB	PDGFRA	CDC42	MAP2K1	MAP2K2	HGF	VCL	SHC2	SHC3	CUL3	ARL2	CSF2RB	RASAL1	PHB	RASAL2	RASAL3	CSF2RA	RASGRP3	RAP1B	RAP1A	FGF20	MARK3	FGF23	CDC14A	FGF22	PSPN	IL2	FGF16	ERBB2	IL3	IL5	DLG2	GDNF	PTPRA	FGF19	FGF18	NF1	FGFR4	MAP3K11	BCL2L1	FGF10	FLT3	ITGB3	RASGRF2	RASGRF1	ARRB1	LAMTOR2	ARRB2	DUSP16	SPRED3	LAMTOR3	SPRED2	SPRED1	DUSP10	RASGEF1A	PPP2R5E	KSR1	PPP2R5B	PPP2R5A	PPP2R5D	NRG1	PPP2R5C	KSR2	NRG2	RASA3	NRG3	RASA4	NRG4	RASA1	IL3RA	RASA2	MET	CAMK2B	CAMK2D	ABHD17C	IL2RG	PDE6D	MAPK3	CSK	NCAM1	CAMK2G	ANGPT1	PTPN11	MAPK12	ABHD17B	ABHD17A	IL2RA	IL2RB	KRAS	TEK	SHC1	PTPN7	EGF	PTPN3	EGFR	NRAS	SOS1	HRAS	PPP2R1B	CDC42EP5	CDC42EP3	CDC42EP2	CDC14B	SEPT7	SPTAN1	ETV4	MAPK6	MAPK4	SPTB	SPTBN4	SPTBN5	SPTA1	TYK2	SPTBN1	SPTBN2	PPP1CB	FGB	PPP2R1A	FGA	VWF	PRKACA	FGG	JUN	
DEFECTIVE SLC24A1 CAUSES CONGENITAL STATIONARY NIGHT BLINDNESS 1D (CSNB1D)%REACTOME%R-HSA-5619077.1	Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D)	SLC24A1	
MRNA DECAY BY 3' TO 5' EXORIBONUCLEASE%REACTOME DATABASE ID RELEASE 74%429958	mRNA decay by 3' to 5' exoribonuclease	EXOSC7	EXOSC6	EXOSC5	EXOSC4	EXOSC9	NT5C3B	EXOSC8	EXOSC3	TTC37	EXOSC2	SKIV2L	EXOSC1	HBS1L	DIS3	WDR61	DCPS	
GPCR LIGAND BINDING%REACTOME%R-HSA-500792.3	GPCR ligand binding	RRH	EDNRA	EDNRB	UTS2R	GPR37L1	UTS2B	CXCR4	NLN	PPY	PDYN	NTSR1	CCR10	NTSR2	NMB	XCR1	NMBR	NMS	NMU	CX3CL1	BRS3	CCKAR	FFAR3	CXCL8	FFAR2	CCL2	EDN1	EDN2	EDN3	CCKBR	NPB	CXCR5	CXCR6	CXCR1	NPW	CXCR3	CXCR2	KISS1R	F2RL1	PMCH	NPY2R	GHSR	NPY1R	APLNR	SUCNR1	NTS	OPN4	OPN3	OPN5	PYY	NMUR2	NMUR1	TAS2R7	CXCL6	TAS2R9	CXCL9	TAS2R8	MLNR	PSAP	CXCL3	CXCL5	CCR5	BDKRB2	BDKRB1	TAS2R1	PPBP	TAS2R3	TAS2R5	TAS2R4	NPY5R	CORT	C5AR2	C5AR1	C5	NPY4R	P2RY12	OPRL1	S1PR3	AVP	S1PR2	S1PR5	S1PR4	KISS1	SMO	PTCH1	GNAS	OXTR	AVPR1B	OXT	AVPR1A	PTGFR	TBXA2R	PTGDR2	PTGER1	GABBR2	PTGER3	GABBR1	HEBP1	ANXA1	FPR1	FPR3	FPR2	CCL11	CCL19	CCL22	AGT	CCL20	CXCL10	CCL5	CCL4	CCL3	OPN1SW	OPN1MW	OPN1LW	OPN1MW2	CCR1	CCR2	OPRD1	CCL3L1	CCL3L3	CXCL1	CXCL2	CD55	C3	GPR17	P2RY13	P2RY10	P2RY14	LPAR4	P2RY6	APP	P2RY4	LPAR6	P2RY2	ADORA3	P2RY1	ADORA1	SSTR3	SAA1	MCHR1	GRP	FFAR4	FFAR1	GLP1R	UCN	VIPR1	WNT2B	VIPR2	SCT	IHH	ADM	PTH1R	FZD10	ADGRE1	ADGRE2	CRHBP	SHH	CYSLTR2	ADGRE5	UCN3	UCN2	ADGRE3	GLP2R	WNT9B	PTH2R	WNT9A	WNT16	CXCL12	GIP	ADCYAP1	CRH	IAPP	CALCA	RHO	RAMP2	ADCYAP1R1	RAMP3	CALCRL	CALCB	DHH	GIPR	PTH	WNT8A	WNT8B	PTH2	PTHLH	CRHR1	GHRHR	WNT6	CALCR	WNT1	WNT2	WNT3	WNT4	FZD1	WNT10B	WNT10A	WNT3A	FZD7	WNT7B	PTCH2	FZD9	SCTR	FZD8	AGTR2	WNT7A	GCG	ADM2	NPBWR1	GHRH	NPBWR2	VIP	RAMP1	GPR18	GPRC6A	GPR37	GPR35	GPR31	SST	NPFFR2	NPFFR1	NPFF	QRFPR	HCRT	QRFP	HCRTR2	PROKR1	HCRTR1	PROKR2	GPR55	GPR68	GPR65	CXCL13	CXCL16	UTS2	CXCL11	ECE1	F2RL2	PRLHR	F2RL3	ADORA2A	GNGT1	CCL7	GNGT2	CCL1	WNT5A	APLN	TAS2R20	GNG3	OXER1	GNG10	GNG2	TAS2R10	WNT11	TAS2R13	GNG5	TAS2R14	GNG4	TAS2R16	GNG7	TAS2R19	GNG8	KEL	FZD3	FZD2	TAS2R40	FZD5	TAS2R41	TAS2R42	FZD4	TAS2R43	FZD6	LPAR1	TAS2R46	LPAR2	GNG12	LPAR3	GNG11	GNG13	PENK	TAS2R30	TAS2R31	GNB2	TAS2R38	TAS2R39	GNB1	LPAR5	GNB4	GNRH2	GNB3	GNRH1	GNB5	TAS2R60	MLN	GNRHR	CCR9	CCR8	CCR7	CCR6	CCR4	CCR3	OXGR1	TAS2R50	GAL	PRLH	XK	CCRL2	CASR	PTAFR	MCHR2	HCAR2	HCAR3	HCAR1	TAC3	TAC1	GRM1	LTB4R	GRM3	GRM2	GRM5	GRM4	GRM7	GRM6	GPER1	GRM8	SSTR1	SSTR2	SSTR4	SSTR5	CNR2	CNR1	TAS1R2	TAS1R1	TAS1R3	CCK	AGTR1	CHRM2	CHRM3	ACKR4	CHRM1	ACKR3	CHRM4	ACKR2	CHRM5	ACKR1	HTR2B	HTR2C	ADRA1D	RXFP4	RXFP1	ADRB1	RXFP2	HTR2A	GRPR	ADRB2	RXFP3	ADRA1B	HTR4	C3AR1	ADRA1A	PTGDR	PROK2	HRH1	HTR6	PROK1	HTR7	CMKLR1	LHB	HRH3	HRH2	HRH4	DRD1	DRD2	MC2R	TRHR	CGA	DRD3	DRD4	DRD5	MC1R	TAAR8	HTR1E	TAAR9	GALR3	GALR2	HTR1F	TAAR6	GALR1	MC4R	GPR39	HTR1D	NPY	HTR1A	FSHB	GPR183	HTR1B	TAAR5	PNOC	TAAR2	GPBAR1	GPR132	ADRA2C	MC3R	HTR5A	TAAR1	TACR2	TACR1	ADRA2A	FSHR	TACR3	NPSR1	GPR143	ADRB3	PTGER4	PTGER2	RGR	CCL13	NPS	CCL17	CCL16	GPHA2	CCL25	P2RY11	CCL21	MC5R	GPHB5	OPRM1	GPR4	CYSLTR1	LHCGR	CCL28	CCL27	OPRK1	MTNR1A	S1PR1	LTB4R2	RLN2	MTNR1B	RLN3	INSL3	TSHB	PTGIR	AVPR2	KNG1	ADORA2B	TSHR	POMC	TRH	F2R	INSL5	F2	XCL2	XCL1	CX3CR1	PF4	
HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS%REACTOME%R-HSA-629587.3	Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	CHRNA4	CHRND	CHRNG	CHRNE	CHRNB2	CHRNA3	CHRNB4	
GRB2 EVENTS IN EGFR SIGNALING%REACTOME DATABASE ID RELEASE 74%179812	GRB2 events in EGFR signaling	TGFA	AREG	EGFR	NRAS	EPGN	SOS1	HRAS	EREG	BTC	EGF	HBEGF	
CELL-CELL COMMUNICATION%REACTOME%R-HSA-1500931.4	Cell-Cell communication	CASK	JUP	ITGA6	CD47	CTNNB1	FBLIM1	FLNC	LIMS2	FERMT2	PIK3CB	CTNNA1	ARHGEF6	PLEC	TESK1	PARVB	RSU1	LIMS1	FLNA	CDH15	CDH1	NCK2	FYB	CDH4	CDH2	CD151	COL17A1	ITGB4	PTPN11	LAMC2	CTNND1	F11R	CLDN2	CLDN1	CDH9	PVR	CDH8	CDH7	ACTN1	CLDN22	CDH6	ACTN4	CDH5	CLDN20	CDH3	CLDN23	CLDN11	CLDN6	CLDN10	CLDN4	CLDN3	CLDN15	CLDN14	CLDN9	CLDN8	PARD3	SIRPG	KIRREL3	CDH10	KIRREL2	CLDN12	CLDN7	KIRREL	SIRPA	MAGI2	CDH11	CD2AP	CLDN19	CDH12	NPHS1	CLDN18	CDH13	CLDN17	WASL	ANG	CLDN16	CDH17	NCK1	CDH18	PARD6G	PARD6B	ACTN3	LAMA3	PARD6A	CDH24	CADM3	CADM1	CADM2	MPP5	INADL	SDK1	LAMB3	PVRL4	PVRL3	SPTAN1	PVRL2	SDK2	PVRL1	CRB3	PTK2B	SPTBN1	PTPN6	ITGB1	DST	PIK3R2	PIK3R1	PIK3CA	TYROBP	PXN	SKAP2	ILK	FYN	ACTN2	CLDN5	IQGAP1	SIRPB1	VASP	PRKCI	PTK2	
WNT LIGAND SECRETION IS ABROGATED BY THE PORCN INHIBITOR LGK974%REACTOME DATABASE ID RELEASE 74%5340573	WNT ligand secretion is abrogated by the PORCN inhibitor LGK974	PORCN	
INTESTINAL ABSORPTION%REACTOME DATABASE ID RELEASE 74%8963676	Intestinal absorption	SLC2A2	RSC1A1	SLC5A1	SLC2A5	
PAUSING AND RECOVERY OF HIV ELONGATION%REACTOME%R-HSA-167290.2	Pausing and recovery of HIV elongation	CCNK	NELFB	CTDP1	ELL	CCNT1	SUPT4H1	POLR2A	TCEB3	POLR2B	TCEB2	POLR2C	TCEB1	NELFA	POLR2D	NELFCD	TCEB3C	POLR2E	TCEB3CL	POLR2F	TCEB3B	NELFE	GTF2F1	POLR2G	SUPT16H	GTF2F2	POLR2H	SSRP1	POLR2I	SUPT5H	POLR2J	CDK9	TCEA1	POLR2K	TCEB3CL2	POLR2L	CCNT2	
TLR3-MEDIATED TICAM1-DEPENDENT PROGRAMMED CELL DEATH%REACTOME%R-HSA-9013957.2	TLR3-mediated TICAM1-dependent programmed cell death	RIPK3	TLR3	TICAM1	CASP8	RIPK1	FADD	
REGULATION OF RUNX2 EXPRESSION AND ACTIVITY%REACTOME DATABASE ID RELEASE 74%8939902	Regulation of RUNX2 expression and activity	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	CBFB	PSME3	PSME4	PSME1	PSME2	PSMD10	SKP2	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PPARGC1A	PSMB10	PSMA7	NKX3-2	CUL1	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	TWIST1	WWP1	ESR1	NR3C1	HIVEP3	SMURF1	STUB1	MSX2	RBX1	BMP2	GSK3B	DLX5	ESRRA	DLX6	STAT1	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PPARGC1B	PSMA5	
SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS%REACTOME%R-HSA-4551638.5	SUMOylation of chromatin organization proteins	PHC2	PHC1	NUP62	NDC1	SEC13	NUP133	HDAC4	PHC3	CBX5	HIST4H4	NUP50	SUMO3	SUMO2	NUP54	RING1	SUZ12	HIST2H4A	HIST2H4B	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	SATB1	NUP107	SUMO1	NUP188	HDAC2	UBE2I	HDAC1	CBX8	CBX4	CBX2	NUP214	L3MBTL2	NUP210	NUP93	BMI1	SATB2	PIAS1	NUP205	POM121	CHD3	AAAS	NUP160	NUP85	TPR	NUP88	PCGF2	NUP155	RNF2	HIST1H4K	HIST1H4L	NUP153	ZBED1	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	
STEROLS ARE 12-HYDROXYLATED BY CYP8B1%REACTOME DATABASE ID RELEASE 74%211994	Sterols are 12-hydroxylated by CYP8B1	PTGIS	CYP8B1	
BMAL1:CLOCK,NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION%REACTOME DATABASE ID RELEASE 74%1368108	BMAL1:CLOCK,NPAS2 activates circadian gene expression	RXRA	TBL1XR1	TGS1	AVP	CARM1	TBL1X	CLOCK	NPAS2	NAMPT	MED1	BHLHE41	DBP	CCRN4L	KLF15	SERPINE1	HELZ2	ARNTL2	ARNTL	NCOA1	PPARA	F7	NCOA2	CHD9	NCOA6	CREBBP	BHLHE40	SMARCD3	
NITRIC OXIDE STIMULATES GUANYLATE CYCLASE%REACTOME%R-HSA-392154.1	Nitric oxide stimulates guanylate cyclase	PDE10A	KCNMB1	KCNMB2	PRKG2	KCNMB3	KCNMB4	PDE5A	MRVI1	PDE9A	ITPR1	PDE11A	PDE2A	PDE1B	PDE1A	GUCY1B3	KCNMA1	NOS1	NOS2	NOS3	GUCY1A3	GUCY1A2	
TRANSPORT OF ORGANIC ANIONS%REACTOME DATABASE ID RELEASE 74%879518	Transport of organic anions	SLCO4A1	ALB	SLCO4C1	SLCO1A2	SLCO1B1	SLCO2A1	SLCO2B1	AVP	SLCO1B3	SLC16A2	SLCO1C1	
MUSCLE CONTRACTION%REACTOME DATABASE ID RELEASE 74%397014	Muscle contraction	NKX2-5	SCN4A	ITGB5	SCN4B	PAK2	GATA4	AKAP9	KCNJ14	SLN	SCN7A	KCNK1	KCNK2	KCNK3	KCNK4	STIM1	ORAI2	SCN11A	ORAI1	ABCC9	VIM	SCN10A	KCNJ11	ACTA2	RYR1	KCNJ2	VCL	RYR2	ATP2A3	KCNJ4	ATP2A2	ATP2A1	RYR3	SLC8A3	CLIC2	KCNJ12	MYL12B	TRDN	MYL6	ASPH	MYH11	MYL9	SRI	KCNK13	PLN	HIPK1	ATP2B4	ANXA1	ATP2B3	HIPK2	ATP2B2	CACNG6	ATP2B1	CACNG7	CACNA2D2	FGF14	RANGRF	FGF13	FGF12	FGF11	ANXA2	ITGA1	FKBP1B	TNNI3	DMPK	DMD	CAMK2B	CAMK2D	CACNB1	CACNB2	NPPC	NPR1	NPR2	CAMK2G	CORIN	SCN1B	SCN1A	TRIM72	GUCY1B3	DYSF	LMOD1	MYL6B	ACTG2	MYLK	CALD1	ANXA6	MYL10	GUCY1A3	GUCY1A2	CAV3	TPM4	TPM3	TBX5	TPM2	TPM1	SCN3B	SORBS1	SORBS3	SCN3A	MYLPF	AHCYL1	MYL5	WWTR1	MYL7	TRPC1	SCN2A	SCN2B	TNNI1	TNNI2	MYBPC3	TMOD1	MYBPC1	MYBPC2	ACTN3	TMOD4	TNNC1	TMOD3	TNNC2	TMOD2	NEB	MYL4	CACNG8	DES	MYH3	MYL1	TNNT1	MYL2	TNNT2	MYL3	CACNG4	TNNT3	MYH8	ATP1B3	TCAP	ATP1B2	MYH6	ATP1B1	TTN	ATP1A4	SCN9A	ATP1A3	ATP1A2	KCNH2	ATP1A1	KCNK10	KCNK12	KCNK15	NOS1	NPPA	KCNE1	KCNK16	KCNE2	KCNK17	KCNE3	FXYD4	KCNK18	KCNE4	FXYD3	SCN8A	KCNQ1	KCNE5	PXN	KCNK5	FXYD2	KCNIP1	FXYD1	KCNIP2	FXYD7	KCNIP3	FXYD6	KCNIP4	CACNA1C	ACTN2	PRKACA	CAMK2A	KCNK6	ITPR1	KCNK7	TLN1	ITPR2	MYL12A	ITPR3	KCNK9	KAT2B	KCND1	KCND2	KCND3	SLC8A1	SLC8A2	SCN5A	PAK1	
TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS%REACTOME DATABASE ID RELEASE 74%159234	Transport of Mature mRNAs Derived from Intronless Transcripts	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	CPSF1	CPSF3	AAAS	CPSF2	NUP160	WDR33	NUP85	NCBP1	FIP1L1	TPR	NCBP2	NUP88	SYMPK	EIF4E	CPSF4	NUP43	RAE1	SLBP	RANBP2	NUP155	NUP35	NUPL2	NUP37	NUP107	NUP153	NUP188	NXF1	
INTRAFLAGELLAR TRANSPORT%REACTOME DATABASE ID RELEASE 74%5620924	Intraflagellar transport	IFT80	DYNLL1	IFT81	DYNC2LI1	WDR60	HSPB11	WDR34	DYNLL2	WDR19	TTC30B	TRIP11	TTC30A	TCTEX1D1	TCTEX1D2	IFT20	IFT22	IFT27	KIF17	DYNLRB2	DYNLRB1	TTC26	TCTE3	IFT43	IFT46	IFT74	CLUAP1	KIF3B	TNPO1	KIF3C	IFT172	DYNC2H1	IFT88	KIF3A	TTC21B	IFT122	IFT52	KIFAP3	IFT57	IFT140	WDR35	TRAF3IP1	
PROTEIN METHYLATION%REACTOME DATABASE ID RELEASE 74%8876725	Protein methylation	EEF2KMT	CAMKMT	VCPKMT	RPS2	EEF1A1	N6AMT2	HSPA8	VCP	PRMT3	EEF2	ETFB	METTL10	KIN	METTL22	METTL20	METTL21A	
FGFR2 ALTERNATIVE SPLICING%REACTOME DATABASE ID RELEASE 74%6803529	FGFR2 alternative splicing	HNRNPA1	ESRP1	POLR2A	POLR2B	POLR2C	POLR2D	NCBP1	NCBP2	POLR2E	POLR2F	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	RBFOX2	TIA1	HNRNPM	HNRNPF	PTBP1	ESRP2	TIAL1	HNRNPH1	
ASSEMBLY OF THE SARS-COV-2 REPLICATION-TRANSCRIPTION COMPLEX (RTC)%REACTOME DATABASE ID RELEASE 74%9694271	Assembly of the SARS-CoV-2 Replication-Transcription Complex (RTC)	
HIV TRANSCRIPTION INITIATION%REACTOME%R-HSA-167161.2	HIV Transcription Initiation	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	CCNH	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	TBP	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	GTF2A1	CDK7	GTF2A2	GTF2B	ERCC3	TAF9	TAF1L	AK6	ERCC2	GTF2E1	GTF2E2	TAF7L	MNAT1	TAF9B	TAF15	TAF12	TAF13	TAF10	
INTERLEUKIN-38 SIGNALING%REACTOME DATABASE ID RELEASE 74%9007892	Interleukin-38 signaling	IL1F10	IL1RAPL1	IL1RL2	MAPK8	
CELLULAR RESPONSES TO STRESS%REACTOME%R-HSA-2262752.6	Cellular responses to stress	DYNLL1	AJUBA	VCP	UBA52	DYNC1I2	DCTN2	DCTN3	UBB	UBC	EIF2S2	EIF2S1	RPS27A	NBN	EIF2S3	SUZ12	DYNC1H1	RPA1	RPA2	EPO	MRE11A	RAD50	RPA3	CEBPB	EHMT1	CXCL8	CEBPG	HSPA5	RPL4	RPL5	ASNS	RPL30	DDIT3	RPL3	RPL32	ATF3	RPL31	ATF4	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	IL6	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	SESN2	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	MAPKAPK5	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	GPX2	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	TXNRD1	RPL11	MAPKAPK2	RPL36A	RPS27L	HMGA1	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	HSPA8	MAPK14	MAPK11	RPL22L1	FAU	RPL26L1	HSPB8	CCAR2	HSBP1	SIRT1	DNAJC2	DNAJC7	FKBP4	CRYAB	RPS19BP1	HSPA4L	HSPA14	HSPA13	HDAC6	DNAJB1	BAG5	C11orf73	HSPH1	BAG2	DNAJB6	BAG3	BAG1	HSF1	HSPA1L	ST13	HSPA4	PTGES3	NCF1	HSPA6	NCF2	HSPA2	NCF4	HSPA12A	HSPA12B	CYBB	GPX1	RBX1	EP300	H1F0	HIST1H1D	HIST1H1E	HIST1H1A	HIST1H1B	HIST1H1C	PPP1R15A	CAMK2B	CAMK2D	CDKN1A	CDKN1B	CAMK2G	MDM2	MDM4	EEF1A1	RB1	NUP107	NUP188	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	NUP214	NUP210	HIST1H2AJ	NUP93	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	NUP205	POM121	EHMT2	H2AFB1	HIST1H3J	ATF2	AAAS	UBE2D3	NUP160	MAP2K3	HIST1H3A	NUP85	RBBP4	MAP2K4	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	RBBP7	HIST1H3I	HIST1H3B	MAPKAPK3	HIST1H3C	HIST1H3D	HIST1H3E	NUP155	H3F3B	HIST1H4K	HIST1H4L	MAP2K7	MAP2K6	JUN	AR	H3F3A	NUP153	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	DYNC1LI1	DYNC1LI2	LMNB1	HIST2H2AC	FOS	H2AFJ	NUP62	UBE2D1	CDC23	NDC1	CDC26	CDC27	SEC13	NUP133	ANAPC7	H2AFZ	UBE2E1	H2AFX	H2AFV	CCNA2	CCNA1	HIST2H2BE	CCNE2	CCNE1	HIST4H4	NUP50	ANAPC4	ANAPC5	NUP54	EZH2	ANAPC1	HIST1H2BN	HIST1H2BM	ANAPC2	ANAPC15	HIST1H2BO	ANAPC16	RING1	HIST1H2BJ	ANAPC10	HIST1H2BI	MAPK9	ANAPC11	HIST1H2BL	MAPK8	MAPK7	FZR1	HIST1H2BK	MAPK10	HIST2H4A	HIST2H4B	MAPK1	UBE2C	NUP43	RAE1	RANBP2	UBE2S	CDC16	CDK2	HIST3H3	NUP35	NUPL2	NUP37	CAPZB	CITED2	DYNLL2	ATP7A	DCTN6	DCTN5	DCTN1	DCTN4	HSP90AB1	CYCS	PSMD8	PSMD9	PSMD6	ATF5	PSMD7	ASF1A	PSMD4	SEH1L	PSMD5	NPRL2	DYNC1I1	PSMD2	NPRL3	PSMD3	HIF1A	PSMD1	PRDX3	WDR59	EIF2AK1	E2F1	EIF2AK4	PRDX6	PSMA5	NOX4	PSMA6	CAPZA3	NOX5	PSMA3	PSMA4	CAPZA1	MIOS	PSMA1	PSMA2	GSTP1	CAPZA2	PSME3	WDR24	UBE2D2	PSME4	UBN1	PSME1	EGLN1	PSME2	EGLN3	SP1	GATSL3	EGLN2	PSMD10	WTIP	PSMB11	ERO1L	ACTR10	PSMD12	SESN1	PSMD11	MAP3K5	PSMD14	ERF	PSMD13	TNIK	STIP1	PSMB10	C7orf60	PSMA7	HIF1AN	GPX3	RELA	PSMA8	GPX6	PSMB6	GPX5	PSMB7	GPX8	PSMB4	GPX7	PSMB5	IMPACT	PSMB2	GCN1L1	PSMB3	SH3BP4	PSMB1	E2F2	PSMF1	FNIP1	SHFM1	FNIP2	EPAS1	PSMB8	ATOX1	NFKB1	DNAJA1	PSMB9	DNAJA4	DNAJA2	PSMC5	AQP8	PSMC6	NUDT2	PSMC3	CHAC1	PSMC4	C12orf66	PSMC1	LIMD1	PSMC2	MINK1	ITFG2	DEPDC5	KPTN	HIRA	MAP4K4	ETS1	ETS2	NR3C2	TXN2	GATSL2	SZT2	HIGD1A	EP400	HMGA2	CABIN1	FLCN	CA9	KDM6B	VHL	HSPA9	SOD3	SOD1	CCS	E2F3	BMI1	MTOR	MLST8	TRIB3	GSK3B	CAT	CAMK2A	CDK4	RNF2	TCIRG1	ATP6V1E1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	CREBBP	ATP6V1B2	ATP6V0D1	EED	ATP6V0D2	TP53	ARNT	ATP6V0C	ATP6V1B1	PHC2	ATP6V1A	PHC1	TNRC6C	ATP6V1H	MOV10	AGO3	PHC3	AGO4	ATP6V1G3	ATP6V0E2	AGO1	ATP6V1D	PRDX2	ATP6V1C1	PRDX1	ATP6V1C2	SOD2	ATP6V1F	TNRC6A	TNRC6B	IGFBP7	VENTX	TCEB2	CDKN2D	TCEB1	CDKN2B	CDKN2C	IFNB1	ATR	PGR	HIF3A	RPTOR	ATM	SLC38A9	FKBP5	RRAGA	RRAGC	RRAGB	RHEB	AKT1S1	RRAGD	LAMTOR2	CDK6	CDKN2A	LAMTOR1	LAMTOR4	LAMTOR3	LAMTOR5	BAG4	STAT3	GRB10	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	CUL2	TXN	VEGFA	TFDP1	IL1A	TFDP2	CBX8	CBX6	CBX4	CBX2	TINF2	TERF1	NR3C1	TERF2	POT1	TERF2IP	ACD	CYBA	KAT5	P4HB	YWHAE	ACTR1A	HSP90AA1	ID1	
RELEASE OF HH-NP FROM THE SECRETING CELL%REACTOME DATABASE ID RELEASE 74%5362798	Release of Hh-Np from the secreting cell	IHH	GPC5	NOTUM	ADAM17	SCUBE2	DISP2	SHH	DHH	
HS-GAG DEGRADATION%REACTOME DATABASE ID RELEASE 74%2024096	HS-GAG degradation	AGRN	NAGLU	GLB1	IDUA	GPC1	IDS	SDC4	SDC3	GPC3	GLB1L	SDC1	GPC2	GPC5	HSPG2	GPC4	GPC6	HPSE	SGSH	HPSE2	GUSB	SDC2	
CD28 DEPENDENT VAV1 PATHWAY%REACTOME DATABASE ID RELEASE 74%389359	CD28 dependent Vav1 pathway	CD28	PAK3	VAV1	PAK2	CD86	FYN	CD80	CDC42	LCK	RAC1	PAK1	
GLYCOSPHINGOLIPID METABOLISM%REACTOME%R-HSA-1660662.5	Glycosphingolipid metabolism	GLB1	ESYT3	UGT8	ESYT2	ESYT1	ENPP7	B3GALNT1	SMPD4	SMPD1	ASAH2	STS	CPTP	GALC	ARSJ	SMPD3	SMPD2	ARSK	ARSH	ARSI	ARSF	ARSG	ARSD	GM2A	ARSE	GBA	ARSA	HEXB	SUMF2	GLA	SUMF1	HEXA	GLTP	CERK	PSAP	GBA2	NEU2	NEU3	UGCG	ARSB	NEU1	B4GALNT1	GLB1L	ASAH1	CTSA	
DEFECTIVE CYP19A1 CAUSES AROMATASE EXCESS SYNDROME (AEXS)%REACTOME DATABASE ID RELEASE 74%5579030	Defective CYP19A1 causes Aromatase excess syndrome (AEXS)	CYP19A1	
TOXICITY OF BOTULINUM TOXIN TYPE F (BONT F)%REACTOME DATABASE ID RELEASE 74%5250981	Toxicity of botulinum toxin type F (BoNT F)	VAMP1	SV2C	SV2B	VAMP2	SV2A	
INTERLEUKIN-2 SIGNALING%REACTOME DATABASE ID RELEASE 74%9020558	Interleukin-2 signaling	IL2RG	IL2	JAK3	JAK1	PTK2B	STAT5A	STAT5B	IL2RA	SYK	IL2RB	LCK	SHC1	
DISEASES ASSOCIATED WITH SURFACTANT METABOLISM%REACTOME DATABASE ID RELEASE 74%5687613	Diseases associated with surfactant metabolism	SFTPC	SFTPD	CSF2RB	SLC34A2	ABCA3	CSF2RA	SFTPA2	SFTA3	SFTPA1	SFTPB	
RESOLUTION OF AP SITES VIA THE MULTIPLE-NUCLEOTIDE PATCH REPLACEMENT PATHWAY%REACTOME DATABASE ID RELEASE 74%110373	Resolution of AP sites via the multiple-nucleotide patch replacement pathway	PARP2	RFC5	RFC3	FEN1	PCNA	RPA1	RFC4	RPA2	RFC1	LIG1	PARG	PARP1	RFC2	POLE4	POLD3	ADPRHL2	POLB	POLD4	RPA3	POLE2	POLD1	APEX1	POLE3	POLD2	POLE	
LEWIS BLOOD GROUP BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%9037629	Lewis blood group biosynthesis	FUT2	FUT3	ST6GALNAC6	FUT10	FUT11	ST3GAL4	B3GALT2	B3GALT1	FUT4	ST3GAL3	FUT6	FUT5	FUT7	FUT9	B3GALT4	B3GALT5	ST3GAL6	B4GALNT2	
TRANSLATION OF STRUCTURAL PROTEINS%REACTOME%R-HSA-9683701.2	Translation of structural proteins	PRKCSH	GANAB	ST3GAL4	MGAT1	ST3GAL1	ST3GAL2	UBA52	ST3GAL3	ST6GAL1	MOGS	PARP16	PARP14	UBB	PARP10	ST6GALNAC3	PARP6	ST6GALNAC4	PARP4	PARP9	UBC	PARP8	RPS27A	GSK3B	CANX	SUMO1	UBE2I	GALNT1	ST6GALNAC2	
INWARDLY RECTIFYING K+ CHANNELS%REACTOME DATABASE ID RELEASE 74%1296065	Inwardly rectifying K+ channels	KCNJ5	KCNJ6	GABBR1	KCNJ10	KCNJ12	KCNJ1	KCNJ9	KCNJ15	GNG12	KCNJ16	GNG11	KCNJ14	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	KCNJ8	ABCC8	GNGT1	GNGT2	ABCC9	GNG3	GNG10	GNG2	GNG5	GNG4	KCNJ11	GNG7	GNG8	KCNJ2	KCNJ3	KCNJ4	GABBR2	
GLUCONEOGENESIS%REACTOME%R-HSA-70263.2	Gluconeogenesis	ALDOB	ALDOA	GAPDH	PGK1	GOT1	PGK2	GOT2	G6PC	MDH2	SLC25A1	G6PC3	PCK1	PCK2	MDH1	SLC25A10	PC	GPI	SLC37A1	ENO1	ENO2	ENO3	G6PC2	TPI1	SLC25A12	SLC25A11	PGAM1	FBP1	PGAM2	FBP2	GAPDHS	SLC25A13	ALDOC	
DEFECTIVE TPMT CAUSES THIOPURINE S-METHYLTRANSFERASE DEFICIENCY (TPMT DEFICIENCY)%REACTOME%R-HSA-5578995.1	Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)	TPMT	
SYNTHESIS OF DNA%REACTOME DATABASE ID RELEASE 74%69239	Synthesis of DNA	MCM7	MCM8	UBE2D1	CDC23	CDC26	CDC27	SKP2	ANAPC7	UBA52	UBE2E1	CCNA2	CCNA1	CCNE2	CCNE1	MCM3	MCM4	ANAPC4	CUL1	MCM5	ANAPC5	MCM6	ANAPC1	UBB	MCM2	ANAPC2	ANAPC15	ANAPC16	UBC	ANAPC10	ANAPC11	ORC5	ORC4	RPS27A	FZR1	ORC6	ORC1	ORC3	ORC2	CDT1	UBE2C	CDC6	UBE2S	RPA1	CDC16	RPA2	CDK2	RPA3	PRIM2	PRIM1	POLA1	POLA2	DNA2	RFC5	RFC3	FEN1	PCNA	RFC4	RFC1	LIG1	RFC2	POLE4	POLD3	POLD4	PSMD8	POLE2	POLD1	PSMD9	CDC45	PSMD6	GINS1	POLE3	PSMD7	POLD2	GINS2	PSMD4	POLE	GINS3	PSMD5	GINS4	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	RBX1	SKP1	
COMMON PATHWAY OF FIBRIN CLOT FORMATION%REACTOME%R-HSA-140875.4	Common Pathway of Fibrin Clot Formation	SERPINA5	THBD	PF4V1	CD177	FGB	FGA	F10	SERPIND1	F2R	FGG	F2	F5	PROCR	F8	SERPINE2	PROC	SERPINC1	PROS1	PRTN3	F13A1	F13B	PF4	
LAGGING STRAND SYNTHESIS%REACTOME DATABASE ID RELEASE 74%69186	Lagging Strand Synthesis	POLA2	DNA2	RFC5	RFC3	FEN1	PCNA	RPA1	RFC4	RPA2	RFC1	LIG1	RFC2	POLD3	POLD4	RPA3	POLD1	POLD2	PRIM2	PRIM1	POLA1	
DEFECTIVE TRANSLOCATION OF RB1 MUTANTS TO THE NUCLEUS%REACTOME DATABASE ID RELEASE 74%9661070	Defective translocation of RB1 mutants to the nucleus	RB1	
MITOTIC G2-G2 M PHASES%REACTOME DATABASE ID RELEASE 74%453274	Mitotic G2-G2 M phases	CSNK1E	TUBGCP4	TUBG2	DYNLL1	TUBG1	MZT2B	CKAP5	MZT2A	TUBA4A	NME7	PPME1	HAUS2	MZT1	PHLDA1	HAUS1	AKAP9	LCMT1	CEP63	CDK11A	MAPRE1	AJUBA	SFI1	UBA52	OPTN	CCNA2	PAFAH1B1	FBXL18	CCNA1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	CDC25B	DCTN3	CUL1	AURKA	CCNB2	CCNB1	UBB	HAUS8	HAUS7	CENPF	PRKAR2B	UBC	CEP70	CEP72	CEP192	RPS27A	PCNT	CEP76	PPP2CA	CLASP1	CEP78	PPP2CB	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	CDK2	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	WEE1	PPP2R2A	TPX2	HSP90AB1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	E2F1	PSMA5	PSMA6	PSMA3	CDKN1A	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	CDC25A	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	CDC25C	PSMD13	LIN54	LIN37	PSMB10	LIN9	MYBL2	PSMA7	XPO1	LIN52	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	GTSE1	PSMB9	FKBPL	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	FBXL7	PPP2R1B	E2F3	FOXM1	PKMYT1	PPP2R3B	CCNH	CEP57	YWHAE	RBBP4	CETN2	CEP164	CCP110	RBX1	PPP1CB	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	BTRC	HMMR	NINL	CEP290	YWHAG	RAB8A	CDK5RAP2	SKP1	CDK7	OFD1	HSP90AA1	BORA	PPP1R12A	CEP135	FBXW11	TUBB	EP300	CEP131	TUBGCP2	MNAT1	HAUS4	HAUS3	CSNK1D	TUBGCP5	TUBGCP6	HAUS6	TP53	TUBGCP3	HAUS5	
RECOGNITION OF DNA DAMAGE BY PCNA-CONTAINING REPLICATION COMPLEX%REACTOME DATABASE ID RELEASE 74%110314	Recognition of DNA damage by PCNA-containing replication complex	UBA52	DTL	WDR48	UBB	CUL4A	DDB1	UBC	CUL4B	RPS27A	UBE2B	RBX1	RFC5	RFC3	PCNA	RPA1	RAD18	USP1	RFC4	RPA2	RFC1	RFC2	POLE4	POLD3	POLD4	RPA3	POLE2	POLD1	POLE3	POLD2	POLE	
PYRUVATE METABOLISM AND CITRIC ACID (TCA) CYCLE%REACTOME DATABASE ID RELEASE 74%71406	Pyruvate metabolism and Citric Acid (TCA) cycle	GLO1	LDHC	LDHB	LDHA	PDPR	MPC1	MPC2	PDK4	PDK3	PDK2	VDAC1	PDK1	PDP1	PDP2	LDHAL6A	LDHAL6B	FH	FAHD1	MDH2	IDH3G	IDH2	PPARD	DLST	SDHC	DLAT	SDHD	SDHA	SDHB	CS	SUCLA2	NNT	IDH3B	OGDH	SLC16A8	SUCLG2	SLC16A3	SUCLG1	ME3	ME2	ACO2	DLD	IDH3A	RXRA	ADHFE1	D2HGDH	L2HGDH	PDHA2	PDHA1	PDHB	SLC16A1	BSG	GSTZ1	ME1	PDHX	
INSULIN-LIKE GROWTH FACTOR-2 MRNA BINDING PROTEINS (IGF2BPS IMPS VICKZS) BIND RNA%REACTOME%R-HSA-428359.3	Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs IMPs VICKZs) bind RNA	IGF2BP1	IGF2BP3	IGF2BP2	
SRP-DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE%REACTOME DATABASE ID RELEASE 74%1799339	SRP-dependent cotranslational protein targeting to membrane	UBA52	RPS27A	SPCS3	SPCS2	SPCS1	SEC11A	RPL4	SEC11C	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	SRPR	RPL39L	RPN2	RPL41	RPL3L	RPN1	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	DDOST	SSR1	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	SRPRB	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	SRP14	SEC61A2	SEC61A1	SEC61G	SEC61B	SRP19	TRAM1	SRP54	SSR4	SSR2	SSR3	SRP9	SRP72	SRP68	
AMINE OXIDASE REACTIONS%REACTOME%R-HSA-140179.1	Amine Oxidase reactions	MAOB	MAOA	PAOX	
NGF-INDEPENDANT TRKA ACTIVATION%REACTOME%R-HSA-187024.2	NGF-independant TRKA activation	ADCYAP1	NTRK1	ADORA2A	ADCYAP1R1	NTRK2	
ADHERENS JUNCTIONS INTERACTIONS%REACTOME%R-HSA-418990.2	Adherens junctions interactions	PVRL4	PVRL3	PVRL2	PVRL1	JUP	CTNND1	CTNNB1	CDH9	PVR	CDH8	CDH7	CDH6	CDH5	CDH3	CDH15	CDH1	CDH10	CDH11	CTNNA1	CDH12	CDH13	CDH4	ANG	CDH2	CDH17	CDH18	CDH24	CADM3	CADM1	CADM2	
SIGNALING BY PTK6%REACTOME DATABASE ID RELEASE 74%8848021	Signaling by PTK6	CDKN1B	UBA52	PELP1	EGF	CCNE1	CBL	EGFR	NRAS	HRAS	UBB	UBC	EPAS1	HBEGF	RPS27A	CDK2	RAC1	SFPQ	KHDRBS1	KHDRBS2	SRMS	KHDRBS3	PTK6	STAP2	ARHGAP35	DOCK1	ELMO1	ELMO2	NR3C1	RHOA	SOCS3	ERBB2	PTPN1	DOK1	CRK	BCAR1	PXN	AKT1	CCND1	ARAP1	EREG	GPNMB	CDK4	LRRK2	BTC	STAT3	NRG1	NRG2	NRG3	NRG4	RASA1	HIF1A	
DEFECTIVE ALG9 CAUSES ALG9-CDG (CDG-1L)%REACTOME%R-HSA-4720454.2	Defective ALG9 causes ALG9-CDG (CDG-1l)	ALG9	
ACTIVATED NTRK2 SIGNALS THROUGH RAS%REACTOME DATABASE ID RELEASE 74%9026519	Activated NTRK2 signals through RAS	NRAS	BDNF	NTF4	SOS1	HRAS	NTRK2	
SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL%REACTOME%R-HSA-1855204.3	Synthesis of IP3 and IP4 in the cytosol	PTEN	INPP5B	PLCB4	PLCG1	PLD4	INPP5D	OCRL	PLCB3	PLCB1	PLCZ1	PLCB2	INPP5J	ITPK1	PLCE1	SYNJ1	ITPKB	ITPKC	PLCG2	ITPKA	PLCH1	PLCH2	INPPL1	PLCD3	PLCD4	PLCD1	
INTERLEUKIN RECEPTOR SHC SIGNALING%REACTOME%R-HSA-912526.4	Interleukin receptor SHC signaling	IL2RG	CSF2RB	JAK3	JAK1	CSF2RA	IL2RA	IL2RB	GAB2	SHC1	IL2	IL3	PTPN6	IL5	SOS1	PIK3R3	PIK3R2	PIK3R1	PIK3CA	INPP5D	CSF2	PIK3CD	IL5RA	PIK3CB	JAK2	INPPL1	IL3RA	
MUCOPOLYSACCHARIDOSES%REACTOME DATABASE ID RELEASE 74%2206281	Mucopolysaccharidoses	NAGLU	GLB1	IDUA	HGSNAT	GNS	HYAL1	SGSH	GALNS	IDS	GUSB	ARSB	
ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY%REACTOME%R-HSA-435368.1	Zinc efflux and compartmentalization by the SLC30 family	SLC30A3	SLC30A7	SLC30A2	SLC30A6	SLC30A8	SLC30A1	SLC30A5	
THE CITRIC ACID (TCA) CYCLE AND RESPIRATORY ELECTRON TRANSPORT%REACTOME%R-HSA-1428517.1	The citric acid (TCA) cycle and respiratory electron transport	GLO1	LDHC	LDHB	LDHA	PDPR	MPC1	MPC2	PDK4	PDK3	PDK2	VDAC1	PDK1	PDP1	PDP2	LDHAL6A	LDHAL6B	FH	FAHD1	MDH2	IDH3G	IDH2	PPARD	DLST	SDHC	SDHD	DLAT	SDHA	SDHB	CS	SUCLA2	NNT	IDH3B	OGDH	SUCLG2	SUCLG1	ME3	ME2	ACO2	DLD	IDH3A	MT-ND6	NDUFA13	MT-ND4	PDHA2	MT-ND5	PDHA1	NDUFA11	MT-CO1	NDUFA12	TACO1	NDUFA10	COX6A1	MT-ND2	MT-ND3	MT-ND1	COX6B1	COX7A2L	SCO1	SCO2	UQCRC1	MT-CO2	UQCRC2	MT-CO3	TMEM126B	COX19	COX16	NDUFB10	UQCRB	NDUFB11	PM20D1	COX18	UQCRH	COX11	COX14	PDHB	SLC16A1	NDUFV3	CYC1	NDUFV2	NDUFV1	TRAP1	SURF1	BSG	NDUFAF6	NDUFAF7	GSTZ1	UQCRQ	NDUFAF4	ME1	NDUFAF5	NDUFAF2	CYCS	NDUFAF3	NDUFAF1	MT-CYB	COX20	COX7B	COX4I1	ETFA	ETFB	ECSIT	COX7C	UQCRFS1	COX8A	ACAD9	NDUFC2	NDUFC1	COQ10B	COQ10A	NDUFS8	NDUFS7	NDUFS6	NDUFS5	NDUFS4	NDUFS3	NDUFS2	NDUFS1	NDUFB9	NDUFB8	NDUFB7	NDUFB6	NDUFB5	NDUFB4	NDUFB3	ETFDH	NDUFB2	NDUFB1	UQCR11	UQCR10	COX5B	COX5A	NDUFA9	NDUFA8	NDUFA7	TIMMDC1	NDUFA6	NDUFA5	NUBPL	NDUFA4	NDUFA3	NDUFA2	NDUFA1	COX6C	LRPPRC	NDUFAB1	ATP5S	ATP5A1	ATP5C1	ATP5J	ATP5I	ATP5H	SLC16A8	ATP5G3	SLC16A3	ATP5G2	ATP5O	ATP5G1	ATP5L	MT-ATP6	ATP5B	ATP5E	ATP5D	RXRA	ADHFE1	ATP5F1	D2HGDH	MT-ATP8	ATP5J2	L2HGDH	SLC25A27	UCP3	UCP2	UCP1	SLC25A14	PDHX	
MPS VI - MAROTEAUX-LAMY SYNDROME%REACTOME DATABASE ID RELEASE 74%2206285	MPS VI - Maroteaux-Lamy syndrome	ARSB	
PI3K AKT SIGNALING%REACTOME DATABASE ID RELEASE 74%1257604	PI3K AKT Signaling	IRAK4	UBA52	PIP5K1C	EZH2	UBB	RING1	UBC	RPS27A	PPP2CA	SUZ12	PPP2CB	MAPK1	PIK3CD	IRS2	PIK3CB	VAV1	PPARG	IER3	PIP5K1A	PIP5K1B	SNAI1	SNAI2	STRN	MECOM	PHLPP2	PHLPP1	ATN1	MAF1	TRAT1	PIK3AP1	PIP4K2A	PIP4K2B	PIP4K2C	RPS6KB2	FOXO6	USP7	FOXO4	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	GSK3A	PSMD5	PSMD2	PSMD3	PSMD1	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PTEN	PSMD10	TRAF6	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	ESR1	CSNK2A1	IRS1	SRC	CSNK2A2	CD19	BMI1	CSNK2B	PRR5	CD86	PDPK1	MAPKAP1	CD80	PIK3R3	PIK3R2	PIK3R1	RAC2	MTOR	PIK3CA	LCK	AKT2	AKT3	MLST8	CD28	THEM4	AKT1	TRIB3	FYN	RICTOR	FRS2	GSK3B	EREG	RNF2	BTC	PREX2	TRIM27	PDGFB	USP13	TGFA	WWP2	RNF146	NEDD4	KDM1A	MKRN1	FRK	OTUD3	EED	TP53	PHC2	AREG	CREB1	PHC1	FOXO1	TNRC6C	MOV10	AGO3	PHC3	AGO4	AGO1	AGO2	TNRC6A	TNRC6B	KIT	HBEGF	INSR	EPGN	FOXO3	KLB	TNKS2	TNKS	RAC1	FGF1	FGF2	FGF3	FGF4	FGF6	FGF7	FGF9	HDAC2	HDAC1	IL1RL1	XIAP	IL33	PDGFRB	PDGFRA	CASP9	HGF	FGF20	FGF23	FGF22	RPTOR	FGF16	ERBB2	SLC38A9	FGF19	STUB1	TSC2	FGF18	FGFR4	RRAGA	FGF10	RRAGC	BAD	RRAGB	RHEB	PML	AKT1S1	RRAGD	LAMTOR2	LAMTOR1	LAMTOR4	LAMTOR3	LAMTOR5	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	NRG1	PPP2R5C	NRG2	SALL4	NRG3	NRG4	MET	MAPK3	CDKN1A	CDKN1B	PTPN11	MDM2	HDAC5	EGF	GAB1	HDAC7	EGFR	PPP2R1B	CBX8	CBX6	HDAC3	CBX4	CBX2	ESR2	NR4A1	NR2E1	INS	CHD4	CHD3	ATF2	REST	MTA1	RBBP4	RBBP7	MTA2	PPP2R1A	MTA3	RHOG	MBD3	IRAK1	GATAD2B	GATAD2A	JUN	EGR1	MYD88	
TCR SIGNALING%REACTOME DATABASE ID RELEASE 74%202403	TCR signaling	PAK3	RIPK2	PAK2	UBE2D1	UBA52	CUL1	UBB	UBC	PTPN22	RPS27A	PIK3CB	PLCG2	TRAT1	GRAP2	LCP2	PTPRC	FYB	ZAP70	LAT	CD101	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PAG1	IKBKG	MAP3K7	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	CSK	PSMA1	PTPRJ	PSMA2	UBE2D2	PSME3	PSME4	PSME1	PSME2	CDC34	CARD11	PTEN	PSMD10	TRAF6	PSMB11	PSMD12	PSMD11	PRKCQ	PSMD14	UBE2V1	PSMD13	BCL10	PSMB10	MALT1	PSMA7	RELA	PLCG1	PSMA8	PSMB6	UBE2N	PSMB7	PSMB4	TAB2	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	INPP5D	SHFM1	PSMB8	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CD3G	CD3E	CD3D	NCK1	EVL	HLA-DPA1	HLA-DQB2	HLA-DQB1	ENAH	HLA-DQA2	WAS	HLA-DQA1	TRAV19	HLA-DRB5	HLA-DRB4	CD4	HLA-DPB1	HLA-DRA	HLA-DRB3	HLA-DRB1	PDPK1	PIK3R2	PIK3R1	PIK3CA	LCK	BTRC	SKP1	VASP	FBXW11	ITK	PAK1	
INTERFERON ALPHA BETA SIGNALING%REACTOME DATABASE ID RELEASE 74%909733	Interferon alpha beta signaling	IFNA10	JAK1	PTPN11	IRF3	IRF7	IFNA21	IFNA5	IFNA4	IFITM3	IFNA7	IFITM1	PSMB8	IFITM2	IFNA6	IFNA1	IFIT5	IFI35	IFNA2	IFIT1	IFIT3	IFIT2	IFNA8	ISG15	HLA-A	RSAD2	IRF1	HLA-B	IRF2	HLA-C	HLA-F	HLA-G	HLA-E	BST2	IFNB1	RNASEL	IFI6	IP6K2	ISG20	TYK2	XAF1	SOCS3	IFNAR1	ADAR	OASL	PTPN6	OAS1	IRF4	OAS2	OAS3	PTPN1	IRF8	STAT2	IRF5	IRF6	IRF9	SAMHD1	USP18	GBP2	MX2	SOCS1	MX1	ABCE1	EGR1	IFNA13	IFNA14	IFNA16	IFNA17	
ADAPTIVE IMMUNE SYSTEM%REACTOME DATABASE ID RELEASE 74%1280218	Adaptive Immune System	SH3KBP1	DYNLL1	SEC23A	UBA52	SEC24B	SEC24A	DYNC1I2	DCTN2	DCTN3	CUL1	UBB	SEC24D	SEC24C	UBC	RPS27A	DYNC1H1	PIK3CD	PIK3CB	VAV1	PLCG2	CTSC	TRAT1	PIK3AP1	HSPA5	RNF41	UBE2L3	UBE2V2	CDC20	RNF217	TREML1	TREML4	UBE2J2	TREML2	DZIP3	RNF220	SIGLEC9	HCST	UBE2B	KIR3DL1	KIR3DL2	UBE2A	SIGLEC1	SIGLEC8	SIGLEC7	SIGLEC6	SIGLEC5	FBXO27	LTN1	FBXO21	FBXO22	FBXW8	BTN1A1	FBXO17	FBXO15	FBXO10	FBXO11	BLK	FBXO44	FBXO41	FBXO40	FBXO30	FBXO31	OSBPL1A	TRIM71	TRIM69	UNKL	PIANP	COLEC12	PTEN	TRIM50	MGRN1	RCHY1	ZNRF1	ZNRF2	RILP	TRIM41	YWHAB	TRIM39	RNF34	TRIM36	TRIM37	TRIM32	HERC4	PVR	HERC3	HERC1	YWHAZ	FBXO7	HERC6	FBXO9	FBXO2	CD226	TRIM11	FBXL8	CD207	FBXL4	CD200	FBXL7	SH3RF1	ACTR1B	CUL5	RNF144B	GAN	CD81	CD3E	KLHL2	NCK1	CD3D	KLHL3	ICOSLG	KLHL9	HLA-DPA1	KLHL5	PDCD1LG2	HLA-DQB2	HLA-DQB1	UBE3C	CD274	UBE3D	BTLA	BTK	UBE3A	TNFRSF14	UBE3B	HLA-DQA2	WAS	HLA-DQA1	UBE2Z	TRAV19	HLA-DRB5	HLA-DRB4	PVRL2	FBXW12	UBE4A	CD4	HLA-DPB1	UBA6	HLA-DRA	UBA5	HLA-DRB3	CD19	DAPP1	HLA-DRB1	UBE2F	UBE2H	CRTAM	UBE2W	UBE2U	UBE2O	UBA1	UBE2K	NCF1	UFL1	NCF2	TAPBP	NCF4	ASB13	ASB14	RNF6	ASB11	RNF7	ASB12	PRKACG	CYBB	RNF4	PRKACB	ASB17	ASB18	ASB15	RBX1	ASB16	ASB10	SEC61G	SEC61B	KIF3A	HECW2	ANAPC13	MEX3C	RAB7A	NPEPPS	NEDD4	MKRN1	KLRK1	CD300LB	UBR4	UBR2	KIR2DS2	UBR1	CD300LD	CD300LF	NCR2	CD300LG	CD300E	UBOX5	MIB2	KLRD1	TPP2	ITGB5	KBTBD13	ICAM4	ICAM5	ICAM1	FBXL22	FBXL20	ITCH	HECTD1	HECTD2	ITGB7	HECTD3	FBXL19	FBXL18	FBXL15	FBXL16	FBXL13	FBXL14	FBXL12	CBLB	VCAM1	CD79B	CD79A	SH2D1A	SH2D1B	RAET1E	DET1	STIM1	GPR75-ASB3	ORAI2	LAIR2	ORAI1	LAIR1	KBTBD6	KBTBD7	KBTBD8	SIPA1	LMO7	LONRF1	BLMH	THOP1	PARK2	HACE1	CUL3	LRSAM1	LRRC41	HLA-DMA	HLA-DMB	RASGRP3	RAP1B	RAP1A	SPSB2	SPSB1	NEDD4L	SPSB4	UBE2D4	SMURF2	SMURF1	HLA-DOA	HLA-DOB	LAG3	AREL1	UBE2E3	ATG7	UBE2E2	STUB1	UBE2M	ZBTB16	GRAP2	LCP2	XDH	ZNF645	ERAP2	ERAP1	FCGR2B	LRR1	CCNF	KEAP1	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	CD1D	CD1C	CD1B	CD1A	UBE2J1	SLAMF7	SLAMF6	PAG1	PILRB	PILRA	CSK	PTPN11	CD22	CTSO	ARIH2	CTSH	CTSF	CTSE	CD33	NCR1	NCR3	PDIA3	MICA	MICB	NPDC1	HUWE1	AHCYL1	CALR	CD3G	UBE2G1	CLTC	FCGR3A	CLTA	FCGR1A	UBE2G2	YES1	CANX	CD96	KLHL41	OSCAR	PPP2R1B	KLHL42	CD8A	KLHL11	KIR2DL1	KLHL13	KIR2DL2	KIR2DL3	KIR2DL4	KLHL25	PRKCB	KLHL21	KLHL22	BLNK	KLHL20	SEC61A2	SEC61A1	UBE2Q1	UBE2Q2	PJA2	PJA1	UBE2R2	SPTBN2	VPRBP	C3	ASB8	ASB9	LNX1	ASB6	ASB7	ASB4	ASB5	UBE2D3	ASB2	ASB1	RNF115	RNF114	WSB1	RNF123	RNF126	SOCS1	MRC2	TRIM9	TRIM4	KIF5B	MRC1	KIF5A	MYD88	LGMN	CD200R1	KIFAP3	ITGB2	RNF138	ITK	RNF130	CD36	RLIM	RBCK1	RNF19B	DYNC1LI1	RIPK2	RNF19A	DYNC1LI2	TIRAP	DNM1	UBE2D1	TAP2	DNM2	CDC23	KIF20A	TLR1	TAP1	CDC26	DNM3	CDC27	SEC13	SKP2	ANAPC7	FBXO4	UBE2E1	TRAIP	FBXO6	FBXW4	KLC1	TLR6	FBXW5	CLEC4G	KLC4	FBXW10	FBXW7	ANAPC4	KLC3	BTBD1	CTLA4	KLC2	TLR2	ANAPC5	BTN2A2	KIF3B	FBXW9	CD160	RACGAP1	ANAPC1	BTN2A1	FBXW2	GLMN	ANAPC2	BTBD6	KIF3C	RNF182	ANAPC10	ANAPC11	RNF14	PTPN22	FZR1	DTX3L	PPP2CA	KIF18A	TRAF7	PPP2CB	RBBP6	KIF4B	RNF25	KIF4A	CLEC2B	UBE2C	FBXL3	UBE2S	ARF1	CLEC2D	CDC16	KIF11	SIGLEC12	SIGLEC11	SIGLEC10	UBAC1	KIF15	CAPZB	BTN3A1	RNF213	BTN3A3	BTN3A2	LILRA6	LILRA1	LILRA2	LILRA3	LILRA4	LILRA5	NCR3LG1	LILRB1	LILRB2	LILRB3	KIF23	LILRB4	KIF22	LILRB5	TRIP12	CD300A	DYNLL2	KCTD7	UBA3	KLRF1	CD300C	KLRB1	KLRC1	RAP1GAP2	BTNL9	BTNL8	KIF2A	BTNL2	ULBP1	KIF2C	ULBP3	KIF2B	SEC22B	CD40LG	RAP1GAP	KLRG1	VAMP3	DCTN6	DCTN5	DCTN1	DCTN4	PTPRC	ITGAV	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	DYNC1I1	PSMD2	PSMD3	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	CENPE	PSMA6	CAPZA3	PSMA3	KIF26A	PSMA4	HERC2	CAPZA1	PSMA1	PSMA2	CAPZA2	PSME3	UBE2D2	PSME4	FBXO32	IGKV2-28	IGKV1-12	PSME1	PSME2	IGKV3D-20	CDC34	CARD11	IGKV2D-28	PSMD10	TRAF6	PSMB11	CUL7	IGKV4-1	ACTR10	PSMD12	PSMD11	PRKCQ	PSMD14	UBE2V1	PSMD13	BCL10	ITGAL	IGKV2D-30	RASGRP2	PSMB10	MALT1	RASGRP1	PSMA7	RELA	IGKV3-11	LYN	PSMA8	TRIM63	PSMB6	SEC31A	IGKV5-2	PSMB7	UBE2N	PSMB4	PSMB5	TAB2	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	AP1G1	PSMC4	PSMC1	AP1B1	AP1S2	PSMC2	AP1S1	REL	AP1S3	NFKBIE	HLA-A	NFKBIB	B2M	AP1M2	AP1M1	CXADR	VHL	ENAH	LY96	CD99	SELL	TREM1	AMICA1	CD14	TLR4	SOCS3	CD74	PTPN6	PRR5	ITGB1	CD86	PDPK1	MAPKAP1	SH3GL2	CD80	PIK3R3	PIK3R2	PIK3R1	MTOR	PIK3CA	LCK	TYROBP	AKT2	AKT3	MLST8	CD28	THEM4	PPP3CA	AKT1	PPP3CB	TRIB3	MAP3K8	FYN	RICTOR	MAP3K14	ITPR1	ITPR2	ITPR3	PPP3R1	RNF111	CTSA	ICAM2	ICAM3	PAK1	CD209	PAK3	RAF1	PAK2	NFATC1	FBXL5	TCEB2	TCEB1	IFITM1	UBE2L6	IFI30	HERC5	TRIM21	RAC1	WWP1	HLA-B	HLA-C	HLA-F	HLA-G	HLA-E	CDC42	PPIA	NFATC3	UBA7	NFATC2	SYK	FKBP1A	RAPGEF3	RAPGEF4	CDH1	FCGR1B	FYB	ZAP70	LAT	CD101	PTPRJ	CUL2	CTSV	CTSS	NRAS	PLCG1	SOS1	HRAS	CTSL	TREM2	CTSK	AP2A1	INPP5D	AP2A2	LNPEP	CTSD	CTSB	AP2M1	MYLIP	TRPC1	EVL	SAR1B	VAMP8	KCTD6	AP2S1	STX4	ITGA4	CYBA	AP2B1	ACTR1A	PDCD1	PPP2R1A	PRKACA	BTRC	PPL	SKP1	VASP	SIAH2	FBXW11	SIAH1	SNAP23	CD8B	
MEMBRANE TRAFFICKING%REACTOME%R-HSA-199991.6	Membrane Trafficking	SH3D19	SH3KBP1	RALA	DYNLL1	SGIP1	DNAJC6	SEC22A	SEC22C	SEC23A	DENND3	LRP2	RAB21	CFTR	FCHO1	FCHO2	UBA52	UBQLN1	OPTN	UBQLN2	PAFAH1B1	SEC24B	SEC24A	HIP1R	DYNC1I2	TPD52L1	DCTN2	RAB10	NECAP2	DCTN3	NECAP1	RAB14	ST5	SYT11	RAB12	UBB	RAB13	SEC24D	SEC24C	UBC	RINL	TBC1D10C	TBC1D10A	RPS27A	TBC1D10B	AGFG1	LMAN1L	RIN3	ULK1	RIN1	RIN2	DYNC1H1	LMAN2L	STXBP3	SCFD1	SNX2	GJA10	SNX9	SNX5	TBC1D8B	RAB39B	RAB27A	RAB27B	PUM1	SNAP91	MON1A	MON1B	C2CD5	HIP1	GDI1	CTSZ	GDI2	AP4E1	MIA2	MIA3	MAP1LC3B	CTSC	RAB8B	RAB33A	GAK	CTTN	RAB7B	RHOQ	RABGAP1	STX17	ALS2CL	SORT1	RAB11B	SEC23IP	YIPF6	TRIP10	SCARB2	DENND5B	TRAPPC12	TRAPPC11	SLC2A4	CHM	DENND5A	TRAPPC13	SBF2	TRAPPC2L	OCRL	TBC1D20	TBC1D24	TBC1D25	AMPH	DENND6B	DENND6A	TBC1D13	PACSIN2	PACSIN3	TBC1D14	TBC1D17	TBC1D15	PACSIN1	TBC1D16	SYT2	DENND4B	SYT1	DENND4A	CCZ1	ASPSCR1	SYT9	AP4B1	SYT8	ACBD3	IL7R	PICALM	SLC2A8	EPN1	EPN2	TBC1D1	TRAPPC6A	TBC1D2	RABEP1	TBC1D3	TBC1D4	ALS2	TRAPPC6B	TBC1D7	DNASE2	CLVS2	REPS2	CLVS1	REPS1	DTNBP1	YWHAB	YWHAZ	HSPA8	ARPC1A	WASL	CD3D	ACTR3	GNS	ACTR2	CD4	MYO5A	ARPC4	ARPC5	MYO1C	ARPC2	ARPC3	AVP	PLA2G6	KIF3A	EREG	BTC	RAB7A	TGFA	TSG101	VPS4B	VPS4A	MVB12B	MVB12A	VPS36	VTA1	VPS37C	VPS37D	AREG	VPS37A	VPS37B	STAM	SNF8	PLA2G4A	HGS	CHMP2B	CHMP2A	CHMP4C	CHMP4B	UBAP1	CHMP3	CHMP4A	CHMP6	CHMP7	STAM2	VPS25	GRIA1	VPS28	CHMP5	AGPAT3	HBEGF	EPGN	AP3B1	ARRB1	ARRB2	EPS15	SH3GL1	CD3G	CLTC	CLTA	GOLGA2	SPTAN1	ANK2	ANK3	ANK1	SPTB	SPTBN4	SPTBN5	INS	SPTA1	CD59	CD55	SPTBN1	SPTBN2	TMEM115	GOLGB1	FOLR1	BET1	APP	USP6NL	SCOC	SYS1	KDELR1	GOLIM4	GCC2	GCC1	RAB43	RAB41	GOLGA4	GOLGA5	KIF5B	KIF5A	GOLGA1	ARFIP2	KIF21A	KIF21B	KIFAP3	ITSN1	NSF	COG8	COG7	COG6	COG5	COG4	COG3	COG2	COG1	RINT1	DYNC1LI1	RAB30	DYNC1LI2	RAB36	KIF16B	ZW10	DNM1	KDELR2	DNM2	KIF20A	KDELR3	DNM3	KIF20B	SEC13	COPB2	COPA	TMED10	PIP5K1C	COPB1	RHOBTB3	ARL1	KLC1	TGOLN2	KLC4	KLC3	KLC2	GORASP1	KIF3B	RACGAP1	MAN2A2	MAN2A1	VTI1A	RAB1A	KIF3C	RAB6A	RAB6B	SURF4	RAB1B	RAB39A	USO1	M6PR	IGF2R	KIF18A	KIF18B	ALPP	KIF4B	KIF4A	COPE	ARF3	ARF4	ARF1	KIF11	BICD1	USE1	RABEPK	BICD2	KIF15	KIF19	CAPZB	MAN1A2	KIF13B	TMED3	KIF1C	TMED2	MAN1A1	KIF1B	KIF1A	TMED7	SNAP29	TMED9	NAA30	KIF25	COPZ2	KIF23	KIF22	ARFGAP3	KIF6	DYNLL2	BET1L	ARFGAP1	KIF27	COPZ1	RAB33B	ARFGAP2	KIF9	KIFC2	KIF2A	KIFC1	SBF1	PLIN3	NAA35	KIF2C	NAA38	KIF2B	SEC22B	VAMP4	PAFAH1B3	ARF5	PAFAH1B2	CLTCL1	VAMP3	DCTN6	NAPA	DCTN5	NAPB	NBAS	TMF1	STX16	DCTN1	EXOC8	DCTN4	EXOC7	GOSR2	RAB3IP	STX18	GOSR1	NAPG	STX10	RAB11A	CYTH3	CYTH2	EXOC4	ARFRP1	CYTH4	EXOC3	CUX1	EXOC6	VPS51	VPS53	EXOC5	VPS52	BNIP1	EXOC2	MAN1C1	EXOC1	STX6	STX5	VPS54	YKT6	CYTH1	DYNC1I1	RIC1	GALNT2	GALNT1	GBF1	ARCN1	RGP1	CENPE	CAPZA3	KIF26A	CAPZA1	KIF26B	CAPZA2	RAB18	RAB3GAP2	TRIP11	RAB9A	COPG2	VPS45	PREB	COPG1	ACTR10	RAB3GAP1	RAB9B	SEC31A	AP1G1	AP1B1	AP1S2	AP1S1	AP1S3	AP1M2	AP1M1	SH3GL2	AKT2	AKT3	AKT1	WNT5A	TFRC	FTH1	FZD4	FTL	NEDD8	ADRBK1	RAB5A	TF	PIK3C2A	RAC1	PRKAA2	PRKAG1	CLTB	COL7A1	PRKAG2	PRKAG3	MYH9	PRKAB2	TSC2	TSC1	PRKAB1	YWHAQ	SFN	YWHAH	ITSN2	FNBP1L	RABGEF1	GJA1	TFG	GJA3	GJA5	GJA4	GJA9	GJA8	GABARAPL2	FNBP1	SYTL1	GAPVD1	EGF	BIN1	AGTR1	CHRM2	CBL	COPS7B	EGFR	COPS7A	GABARAP	BLOC1S4	GJC1	BLOC1S6	GJC2	BLOC1S1	ADRB2	BLOC1S3	AP2A1	MYO6	SNAPIN	CCZ1B	AP2A2	LNPEP	GJB2	GJB1	GJB4	GJB3	GJB6	LDLRAP1	GJB5	AP2M1	GJB7	DENND1C	DENND1B	SERPINA1	DENND1A	STON1	STON2	CLINT1	AP3S1	TJP1	SLC18A3	DENND2D	DENND2C	DENND2A	RAB3IL1	EPS15L1	TACR1	SAR1B	VAMP8	GJD2	GJD4	VAMP7	GJD3	VAMP2	ARF6	GPS1	AP2S1	GGA2	LMAN1	GGA1	APOB	GGA3	LDLR	ADRBK2	LMAN2	STX4	CHML	TRAPPC10	SNX18	RAB3A	TPD52	AP2B1	RALGAPA2	RAB32	RAB31	RALGAPB	RAB35	RAB38	DVL2	RAB5B	RAB5C	AP4S1	KIAA0319	TXNDC5	ANKRD28	TRAPPC2	SEC16B	TRAPPC3	RAB4A	TRAPPC1	TOR1A	AVPR2	YWHAE	ANKRD27	TRAPPC4	SEC16A	TRAPPC5	ACTR1A	HPS1	HPS4	TRAPPC8	TRAPPC9	SYNJ2	TOR1B	COPS4	COPS3	COPS6	DAB2	SH3GL3	COPS5	YWHAG	CNIH1	RAB8A	SYNJ1	COPS2	CPD	F5	AAK1	COPS8	CNIH2	F8	CNIH3	MCFD2	SNAP23	AP4M1	PPP6C	AP1G2	CSNK1D	PPP6R1	PPP6R3	
GASTRIN-CREB SIGNALLING PATHWAY VIA PKC AND MAPK%REACTOME%R-HSA-881907.1	Gastrin-CREB signalling pathway via PKC and MAPK	RPS6KA1	MAPK3	CREB1	PRKCA	MAPK1	MMP3	CCKBR	EGFR	NRAS	GAST	SOS1	HRAS	RPS6KA3	MAPK7	RPS6KA2	HBEGF	
DEFECTIVE F8 SECRETION%REACTOME%R-HSA-9672397.1	Defective F8 secretion	F8	
CLEARANCE OF DOPAMINE%REACTOME%R-HSA-379401.3	Clearance of dopamine	MAOA	COMT	LRTOMT	SLC6A3	
TOXICITY OF BOTULINUM TOXIN TYPE G (BONT G)%REACTOME DATABASE ID RELEASE 74%5250989	Toxicity of botulinum toxin type G (BoNT G)	VAMP1	VAMP2	SYT1	
SIGNALING BY OVEREXPRESSED WILD-TYPE EGFR IN CANCER%REACTOME%R-HSA-5638302.1	Signaling by Overexpressed Wild-Type EGFR in Cancer	TGFA	AREG	EGFR	EPGN	EREG	BTC	EGF	HBEGF	
HDL REMODELING%REACTOME%R-HSA-8964058.1	HDL remodeling	ALB	APOE	LIPG	CETP	ABCG1	APOC3	LCAT	APOA1	APOC2	
CHROMATIN ORGANIZATION%REACTOME%R-HSA-4839726.2	Chromatin organization	SETD8	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	EZH2	HIST1H2BN	HIST1H2BM	ACTL6B	HIST1H2BO	PRDM9	HIST1H2BJ	HIST1H2BI	ACTL6A	HIST1H2BL	TBL1X	HIST1H2BK	SUZ12	HIST2H4A	HIST2H4B	KDM3A	KDM1B	KDM4A	KAT8	KAT7	SUPT20H	ATXN7L3	CSRP2BP	PADI3	PADI4	PADI1	PADI6	TADA2A	ZZZ3	JAK2	IKBKAP	ING4	ING3	PAX3	SUPT3H	TAF6L	CCDC101	BRD8	ELP2	MECOM	ELP3	ELP4	ELP5	EHMT1	ELP6	JADE1	JADE3	YEATS4	JADE2	TBL1XR1	SUPT7L	MORF4L1	KAT6B	MORF4L2	HAT1	ENY2	TAF5L	MEAF6	MBIP	DMAP1	DR1	MRGBP	YEATS2	KMT2D	TADA1	KMT2A	VPS72	KMT2C	MSL2	MSL3	MSL1	KANSL1	KDM6A	KANSL2	KANSL3	ING5	PRMT5	BRD1	SUV420H2	KMT2E	SUV39H2	SETD2	SETD3	SETD6	SETD7	SUV420H1	KMT2B	WHSC1L1	ASH1L	DOT1L	NSD1	PRDM16	SMYD3	TAF9	KAT6A	ATF7IP	SETDB1	AK6	SETDB2	SMYD2	TAF12	BRPF1	TAF10	BRPF3	WHSC1	DNMT3A	KDM4B	RUVBL2	RELA	NFKB1	RPS2	SMARCA4	SMARCB1	KDM5B	ACTB	EPC1	NCOA1	EP400	NCOA2	SMARCC1	SMARCC2	KDM6B	SMARCA2	PBRM1	ARID2	GPS2	SUV39H1	PRMT7	COPRS	DPY30	AEBP2	CCND1	CDK4	KDM1A	CREBBP	EP300	EED	SETD1B	SETD1A	PHF21A	SAP130	CARM1	OGT	KDM4C	BRWD1	HIST2H2AB	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	HIST1H2AI	HIST1H2AH	HMG20B	HIST1H2AK	HIST2H2BF	HIST3H2A	HDAC2	HDAC1	PADI2	ASH2L	KDM7A	NCOR2	NCOR1	CLOCK	ATXN7	WDR77	PHF20	RUVBL1	HCFC1	SMARCD1	PRMT1	SMARCD2	HDAC8	TADA2B	SMARCE1	MCRS1	WDR5	HDAC10	TRRAP	PRMT6	TADA3	KDM5A	PHF2	HIST1H2AE	HIST1H2AD	KDM5C	SMARCD3	KDM5D	HDAC3	HIST3H2BB	PHF8	HIST1H2AC	UTY	HIST1H2AB	KDM2A	KDM2B	ARID5B	JMJD6	KDM3B	ARID4A	HIST1H2AJ	KDM4D	MINA	ARID4B	RBBP5	ARID1A	ARID1B	HIST2H3A	PRMT3	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	SAP30	HIST1H2BG	HIST2H3D	BRMS1	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	SAP30L	SAP18	EHMT2	H2AFB1	SUDS3	CHD4	HIST1H3J	CHD3	ATF2	REST	HIST1H3A	MTA1	RBBP4	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	RBBP7	HIST1H3B	MTA2	HIST1H3C	MTA3	HIST1H3D	MBD3	HIST1H3E	HIST1H4K	HIST1H4L	GATAD2B	GATAD2A	KAT2B	KAT2A	NFKB2	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	USP22	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
ARYL HYDROCARBON RECEPTOR SIGNALLING%REACTOME DATABASE ID RELEASE 74%8937144	Aryl hydrocarbon receptor signalling	ARNT	AHR	PTGES3	HSP90AB1	AIP	AHRR	ARNT2	
AMINO ACIDS REGULATE MTORC1%REACTOME%R-HSA-9639288.2	Amino acids regulate mTORC1	ATP6V0C	ATP6V1B1	MIOS	ATP6V1A	WDR24	GATSL3	SEC13	ATP6V1H	SESN1	ATP6V1G3	ATP6V0E2	ATP6V1D	ATP6V1C1	ATP6V1C2	C7orf60	ATP6V1F	SH3BP4	FNIP1	FNIP2	C12orf66	ITFG2	DEPDC5	KPTN	GATSL2	SZT2	FLCN	RPTOR	SLC38A9	MTOR	RRAGA	RRAGC	MLST8	RRAGB	RHEB	RRAGD	LAMTOR2	LAMTOR1	LAMTOR4	LAMTOR3	LAMTOR5	TCIRG1	SESN2	ATP6V1E1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	SEH1L	NPRL2	NPRL3	ATP6V1B2	WDR59	ATP6V0D1	ATP6V0D2	
BIOSYNTHESIS OF DHA-DERIVED SULFIDO CONJUGATES%REACTOME%R-HSA-9026395.1	Biosynthesis of DHA-derived sulfido conjugates	LTC4S	GSTM4	
ACYL CHAIN REMODELLING OF PS%REACTOME DATABASE ID RELEASE 74%1482801	Acyl chain remodelling of PS	PLA2G2A	PLA2G4D	MBOAT1	PLA2G4B	OSBPL8	PLA2G4A	OSBPL5	LPCAT4	PLA2G16	LPCAT3	PLA2G10	PLA2G1B	PLA2R1	PLA1A	PLA2G2F	PLA2G5	OSBPL10	PLA2G2D	PLA2G2E	PLA2G12A	PLA2G4F	
DEADENYLATION-DEPENDENT MRNA DECAY%REACTOME DATABASE ID RELEASE 74%429914	Deadenylation-dependent mRNA decay	RQCD1	TNKS1BP1	CNOT6L	CNOT6	DIS3	XRN1	CNOT10	DDX6	CNOT4	PABPC1	LSM1	CNOT7	DCP2	LSM5	LSM4	CNOT1	PATL1	PARN	CNOT11	LSM3	CNOT2	EDC3	EXOSC7	CNOT3	EXOSC6	LSM2	CNOT8	EDC4	EXOSC5	EXOSC4	LSM7	EXOSC9	LSM6	EXOSC8	EIF4E	DCP1B	EXOSC3	EIF4B	EXOSC2	EXOSC1	SKIV2L	DCP1A	EIF4G1	PAIP1	NT5C3B	EIF4A2	EIF4A1	HBS1L	ZCCHC11	WDR61	EIF4A3	DCPS	ZCCHC6	PAN2	PAN3	TTC37	
DEFECTIVE POMT1 CAUSES MDDGA1, MDDGB1 AND MDDGC1%REACTOME DATABASE ID RELEASE 74%5083633	Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1	POMT1	DAG1	POMT2	
RHO GTPASES ACTIVATE PAKS%REACTOME%R-HSA-5627123.2	RHO GTPases activate PAKs	PAK3	PAK2	PPP1CB	PPP1R12B	FLNA	LIMK1	CTTN	RAC1	MYL12B	MYL6	MYH9	MYH14	MYH11	PPP1R12A	MYH10	MYL9	CDC42	MYLK	PAK1	NF2	
HEDGEHOG LIGAND BIOGENESIS%REACTOME%R-HSA-5358346.1	Hedgehog ligand biogenesis	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	HHAT	PSME1	PSME2	PSMD10	PSMB11	VCP	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	SEL1L	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	SYVN1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	NOTUM	PSMC4	PSMC1	PSMC2	DERL2	GPC5	ERLEC1	OS9	P4HB	IHH	SHH	SCUBE2	DISP2	DHH	PSMD8	PSMD9	PSMD6	PSMD7	ADAM17	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
CYTOKINE SIGNALING IN IMMUNE SYSTEM%REACTOME%R-HSA-1280215.5	Cytokine Signaling in Immune system	STAT5A	STAT5B	PIK3CD	IRS2	PIK3CB	VAV1	CRKL	RAPGEF1	JAK2	TALDO1	GSTA2	YWHAB	PRKCD	YWHAZ	MAPKAPK2	STXBP2	HSPA8	TNFSF13	CCR5	MAPK14	MAPK11	EIF4G1	RBX1	ARAF	WDR83	SYNGAP1	GOLGA7	ACTN2	PAQR3	FLT3LG	FRS2	FRS3	EREG	BTC	TLN1	PIK3R4	PDGFB	TGFA	IQGAP1	RCE1	RALGDS	BRAP	ICMT	BRAF	GRIN2B	PTK2	GRIN2D	PPP5C	ARTN	RGL3	RGL1	RGL2	RET	AREG	PEA15	NEFL	JAK3	JAK1	ICAM1	DUSP4	DUSP5	LYPLA1	ITGAX	DUSP2	DUSP1	GFRA1	GAB2	DUSP8	GFRA3	BIRC5	IL17RD	DUSP9	GFRA2	DUSP6	DUSP7	GFRA4	CNKSR2	VCAM1	APBB1IP	HCK	CNKSR1	MRAS	PTPN12	LRRC7	KIT	TLR9	RAPGEF2	HBEGF	SHOC2	DAB2IP	RANBP9	USP17L2	GRIN1	EPGN	ZDHHC9	KBTBD7	KLB	CSF2	ITGA2B	PEBP1	IL5RA	FGF1	FGF2	FGF3	FGF4	PPP1CC	FGF6	FGF7	FNTA	FGF9	FNTB	NRTN	IL1RL1	IL33	PDGFRB	PDGFRA	MAP2K1	MAP2K2	HGF	VCL	SHC2	SHC3	CUL3	ARL2	CSF2RB	RASAL1	PHB	RASAL2	RASAL3	CSF2RA	RASGRP3	RAP1B	RAP1A	FGF20	MARK3	FGF23	FGF22	PSPN	IL2	FGF16	IL3	IL5	DLG2	GDNF	PTPRA	FGF19	FGF18	UBE2M	NF1	FGFR4	MAP3K11	BCL2L1	FGF10	FLT3	ITGB3	RASGRF2	PML	PDE3B	RASGRF1	ARRB1	ARRB2	DUSP16	SPRED3	SPRED2	CNTFR	SPRED1	CNTF	ANXA1	DUSP10	IL20RA	FPR1	RASGEF1A	IL20RB	PPP2R5E	IL22RA2	KSR1	IL31RA	PPP2R5B	IL22RA1	PPP2R5A	HAVCR2	PPP2R5D	NRG1	SERPINB2	ANXA2	PPP2R5C	KSR2	ZEB1	NRG2	CCL11	CTF1	RASA3	STX3	NRG3	CCL19	RASA4	IL12RB1	NRG4	IL12RB2	RASA1	CCL22	IL3RA	CCL20	RASA2	PIK3C3	IL10RB	MET	IL10RA	CLCF1	CAMK2B	CRLF1	CAMK2D	ABHD17C	CSF3	IL2RG	CSF1	PIM1	PDE6D	CDKN1A	IL13RA2	CSK	IL13RA1	NCAM1	TXLNA	CAMK2G	FSCN1	ANGPT1	IL6ST	PTPN11	MAPK12	BOLA2B	HNRNPDL	ABHD17B	ABHD17A	NDN	IL2RA	MCL1	SOCS5	IL2RB	CXCL10	KRAS	LCP1	TEK	PTPRZ1	PTPN7	CCL5	PTPN3	CCL4	CCL3	PDCD4	IL23R	IL27RA	IL12B	IL12A	LGALS9	IL15RA	IL23A	BOLA2	EBI3	CCR1	LIF	IFNLR1	GRB2	IL22	IL20	IL25	IL26	IL24	IL27	CCR2	IL11	IL15	IL19	IL16	IL17RE	OSMR	IL17RC	IL17RB	IL17RA	OPRD1	IL32	IL31	IL34	OSM	BATF	IL17F	IL17C	IL17A	INPPL1	IL4R	IL11RA	CCL3L1	CCL3L3	CNN2	IL9	CXCL1	CXCL2	CA1	BLNK	IL9R	IFNL2	IFNL1	PTK2B	IFNL3	IGHG4	IGHG1	ATF1	APP	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	VRK3	SIGIRR	MAPKAPK3	AGER	HSP90B1	SOCS1	IRAK1	S100A12	MAP2K7	MAP2K6	JUN	NFKB2	MYD88	ITGAM	ITGB2	HMGB1	NKIRAS1	NKIRAS2	LBP	CD36	DUSP3	SQSTM1	RIPK2	IRAK3	IRAK4	FOS	TRAF3	IRF7	PELI1	BIRC2	BIRC3	PELI3	PELI2	NOD1	NOD2	MAPK9	MAPK8	MAPK7	S100B	MAPK10	TNIP2	SAA1	PTPN4	TNFRSF1A	TCP1	ARF1	TNFRSF6B	TNFSF11	TNFRSF8	TNFRSF4	EDAR	TNFRSF11B	TNFRSF11A	TNFRSF17	TNFSF18	TNFSF14	TNFSF15	TNFSF12	TNFRSF9	TNFSF4	UBA3	CD27	RORC	TNFSF9	RORA	TNFSF8	EDA	TNFRSF13B	TNFRSF13C	EDA2R	TNFSF13B	EDARADD	TNFRSF12A	TNFRSF1B	LTA	TNFRSF25	LTB	CD70	CD40LG	LTBR	CAPZA1	TNFRSF18	MIF	HSPA9	PRKG2	CAMK2A	JUNB	IFNA13	IFNA14	IFNA16	IFNA17	TP53	IFNA10	GATA3	FOXO1	IFNA21	SOD2	IFNA5	IFNA4	IFNA7	IFNA6	IFNA1	FOXO3	IFNA2	IFNA8	IRF1	IRF2	CDC42	IFNB1	PTGS2	PPIA	ERBB2	PTPN1	SYK	CSF1R	CRK	BCL2	STAT1	STAT3	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	SHC1	EGF	GAB1	CBL	EGFR	NRAS	PLCG1	SOS1	HRAS	VEGFA	TWIST1	IL18	IL1A	IL1B	LIFR	VAMP7	VAMP2	STX4	OPRM1	P4HB	CASP1	PPP1CB	POMC	PPP2R1A	PRKACA	BTRC	SKP1	HSP90AA1	EGR1	FBXW11	RALA	UBA52	CUL1	UBB	UBC	RPS27A	MAOA	CXCL8	CCL2	EIF4A2	EIF4A1	IL10	IL6	IL7R	BCL6	GSTO1	PIN1	RPLP0	IRAK2	EIF4E	HLA-DPA1	HLA-DQB2	HLA-DQB1	TNFRSF14	HLA-DQA2	HLA-DQA1	HLA-DRB5	HLA-DRB4	CD4	IRS1	HLA-DPB1	SRC	HLA-DRA	HLA-DRB3	HLA-DRB1	SMAD3	TGFB1	NOS2	NEDD4	FCER2	CREB1	MUC1	SDC1	VIM	EIF4A3	ALOX15	STAT6	KPNA7	KPNA4	KPNA5	KPNA2	KPNA3	KPNA1	KPNB1	EIF2AK2	ISG15	FCGR1A	YES1	CANX	NUP107	NUP188	PPP2R1B	IL1RN	IL36A	NUP214	NUP210	IL18RAP	IL36B	SPTAN1	IL1R2	IL36RN	IL36G	IL1F10	SPTB	IL4	NUP93	TOLLIP	SPTBN4	PTPN20	SPTBN5	HIST2H3A	PTPN23	IL18BP	SPTA1	IL13	IL1RAPL1	IL1RL2	SPTBN1	HIST2H3D	PTPN18	SPTBN2	MAP3K3	HIST2H3C	IL37	PTPN13	PTPN14	PTPN9	PTPN5	PTPN2	NUP205	IL18R1	POM121	HIST1H3J	AAAS	NUP160	HIST1H3A	NUP85	CSH1	TPR	PRL	PRLR	HIST1H3F	GHR	HIST1H3G	GH2	NUP88	GH1	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	NUP155	NUP153	CISH	SOCS2	TEC	ALOX5	LMNB1	MTAP	NUP62	TBK1	IRF3	NDC1	SEC13	NUP133	UBE2E1	NUP50	NANOG	NUP54	PPP2CA	PPP2CB	MAPK1	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	MT2A	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	HIF1A	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	TRAF6	PSMD12	IGHE	PSMD11	PSMD14	PRKCQ	UBE2V1	PSMD13	PSMB10	RASGRP1	PSMA7	RASGRP4	RELA	LYN	PSMA8	PSMB6	PSMB7	UBE2N	PSMB4	TAB3	PSMB5	STX1A	TAB2	PSMB2	TAB1	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	SMARCA4	HLA-A	NFKBIB	B2M	SUMO1	SOD1	TRAF2	FASLG	SOCS3	IFNG	IFNGR1	IFNGR2	PTPN6	PIAS1	ITGB1	CD86	IL6R	PDPK1	FN1	CD80	PIK3R3	PIK3R2	PIK3R1	PIK3CA	LCK	AKT2	THEM4	AKT1	TRIB3	MAP3K8	FYN	DLG1	MAP3K14	DLG3	DLG4	CCND1	MSN	RELB	RPS6KA5	RAF1	PAK2	HMOX1	LCN2	IFITM3	RAG2	IFITM1	RAG1	IFITM2	TSLP	IFIT5	UBE2L6	IL7	IFI35	BRWD1	CRLF2	IFI30	MYC	IFIT1	IFIT3	IFIT2	HERC5	TRIM29	TRIM25	TRIM26	TRIM21	TRIM22	GBP6	GBP5	GBP7	RSAD2	HLA-B	HNRNPF	HLA-C	HLA-F	HLA-G	HLA-E	TRIM17	PDE12	TRIM14	TRIM10	BST2	TRIM8	TRIM6	TRIM5	TRIM2	TRIM3	ARIH1	SP100	RNASEL	PTAFR	IFI6	FLNA	COL1A2	FLNB	MID1	UBA7	IP6K2	ISG20	HNRNPA2B1	XAF1	EIF4G3	EIF4G2	CIITA	EIF4E3	ADAR	OASL	TRIM68	TRIM62	DDX58	PPM1B	OAS1	IRF4	OAS2	OAS3	IRF8	IRF5	USP41	IRF6	EIF4E2	IRF9	SAMHD1	USP18	TRIM46	TRIM48	LAMTOR2	GBP2	GBP1	FCGR1B	LAMTOR3	GBP4	TRIM45	GBP3	MX2	MX1	TRIM35	TRIM38	CSF3R	ABCE1	TRIM31	TRIM34	TNF	ADAM17	CFL1	SNRPA1	AIP	CASP3	SNAP25	CTSG	TIMP1	INPP5D	POU2F1	MMP1	MMP2	MMP3	MMP9	CD44	LAMA5	SOS2	CEBPD	IL1R1	TYK2	IL21	IFNAR1	IL21R	STAT4	PITPNA	SOX2	S1PR1	STAT2	F13A1	FGB	FGA	VWF	FGG	RHOU	PRTN3	
RAF-INDEPENDENT MAPK1 3 ACTIVATION%REACTOME DATABASE ID RELEASE 74%112409	RAF-independent MAPK1 3 activation	IL6	MAPK3	PEA15	DUSP16	PTPN11	MAPK1	JAK1	DUSP4	DUSP5	DUSP10	DUSP2	DUSP1	TYK2	DUSP8	CDK1	DUSP9	DUSP6	DUSP7	IL6R	JAK2	MAP2K1	MAP2K2	
DEFECTIVE SLC6A3 CAUSES PARKINSONISM-DYSTONIA INFANTILE (PKDYS)%REACTOME DATABASE ID RELEASE 74%5619081	Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)	SLC6A3	
NCAM SIGNALING FOR NEURITE OUT-GROWTH%REACTOME%R-HSA-375165.3	NCAM signaling for neurite out-growth	CACNB2	CACNB3	MAPK3	CACNB4	NCAM1	CREB1	COL9A1	COL9A3	GFRA1	COL9A2	GFRA2	NRAS	GFRA4	SOS1	HRAS	NCAN	MAPK1	NRTN	AGRN	SPTAN1	SPTB	SPTBN4	COL4A2	SPTBN5	COL4A1	SPTA1	COL6A2	COL4A4	SPTBN1	SPTBN2	PSPN	COL4A3	COL6A1	GDNF	PTPRA	COL6A3	COL4A5	COL6A6	COL6A5	CACNA1D	CACNA1C	FYN	CACNA1H	CACNA1G	CACNA1I	CACNA1S	PRNP	ST8SIA4	CNTN2	PTK2	ST8SIA2	ARTN	RPS6KA5	CACNB1	
REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP (SREBF)%REACTOME%R-HSA-1655829.2	Regulation of cholesterol biosynthesis by SREBP (SREBF)	IDI1	SEC23A	FDPS	MVK	GGPS1	SP1	TGS1	LSS	SEC24B	TM7SF2	SEC24A	SQLE	PMVK	SEC24D	SEC24C	CARM1	TBL1X	KPNB1	GPAM	MED1	SC5D	DHCR7	RAN	NCOA1	PPARA	SCD	NCOA2	NCOA6	SAR1B	SMARCD3	SREBF2	RXRA	TBL1XR1	MBTPS1	ACACB	NFYA	NFYB	CYP51A1	NFYC	ELOVL6	MBTPS2	INSIG2	INSIG1	FASN	MVD	ACACA	FDFT1	HMGCS1	MTF1	SCAP	HELZ2	CHD9	CREBBP	
POLYMERASE SWITCHING ON THE C-STRAND OF THE TELOMERE%REACTOME DATABASE ID RELEASE 74%174411	Polymerase switching on the C-strand of the telomere	POLA2	TEN1	TINF2	TERF1	TERF2	POT1	TERF2IP	ACD	RFC5	RFC3	PCNA	RFC4	RFC1	RFC2	POLD3	POLD4	POLD1	POLD2	PRIM2	DSCC1	PRIM1	CHTF18	CHTF8	OBFC1	CTC1	POLA1	
MYD88 DEFICIENCY (TLR2 4)%REACTOME DATABASE ID RELEASE 74%5602498	MyD88 deficiency (TLR2 4)	LY96	TLR6	MYD88	TIRAP	TLR2	TLR1	CD14	TLR4	BTK	CD36	
BIOSYNTHESIS OF ASPIRIN-TRIGGERED D-SERIES RESOLVINS%REACTOME DATABASE ID RELEASE 74%9020265	Biosynthesis of aspirin-triggered D-series resolvins	LTA4H	ALOX5	
ABORTIVE ELONGATION OF HIV-1 TRANSCRIPT IN THE ABSENCE OF TAT%REACTOME DATABASE ID RELEASE 74%167242	Abortive elongation of HIV-1 transcript in the absence of Tat	NCBP2	POLR2E	POLR2F	GTF2F1	NELFE	GTF2F2	POLR2G	POLR2H	SUPT5H	POLR2I	POLR2J	POLR2K	NELFB	POLR2L	CTDP1	SUPT4H1	POLR2A	POLR2B	POLR2C	NELFA	NCBP1	POLR2D	NELFCD	
THE AIM2 INFLAMMASOME%REACTOME%R-HSA-844615.1	The AIM2 inflammasome	AIM2	PYCARD	CASP1	
SHC-MEDIATED CASCADE:FGFR3%REACTOME%R-HSA-5654704.2	SHC-mediated cascade:FGFR3	FGF4	FGF16	NRAS	FGF9	SOS1	HRAS	FGF18	FGF20	FGF1	FGF23	FGF2	
SHC1 EVENTS IN EGFR SIGNALING%REACTOME DATABASE ID RELEASE 74%180336	SHC1 events in EGFR signaling	TGFA	AREG	EGFR	NRAS	EPGN	SOS1	HRAS	EREG	BTC	SHC1	EGF	HBEGF	
HOMOLOGY DIRECTED REPAIR%REACTOME DATABASE ID RELEASE 74%5693538	Homology Directed Repair	POLK	XRCC1	LIG3	ABL1	UBA52	H2AFX	CCNA2	CCNA1	HIST2H2BE	HIST4H4	MUS81	EME1	EME2	POLH	GEN1	SLX1B	UBB	CLSPN	HIST1H2BN	SPIDR	HIST1H2BM	SLX1A	RTEL1	HIST1H2BO	RAD51AP1	UBC	HIST1H2BJ	HIST1H2BI	SLX4	XRCC2	BRCA1	HIST1H2BL	XRCC3	BRCA2	NBN	PALB2	RPS27A	TOP3A	HIST1H2BK	HIST2H4A	PPP4R2	HIST2H4B	TIPIN	BLM	TIMELESS	PPP4C	RBBP8	RPA1	RPA2	CDK2	MRE11A	HIST3H3	RAD51B	RAD50	RAD51C	RAD51	RPA3	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	RAD52	ERCC4	ERCC1	MDC1	RAD17	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	ATM	UBE2V2	PARP2	RAD51D	RFC5	RFC3	FEN1	PCNA	RFC4	RFC1	RFC2	POLE4	POLD3	POLD4	POLE2	POLD1	POLE3	POLD2	POLE	BABAM1	HERC2	UIMC1	WHSC1	CHEK1	RNF168	RNF8	BRCC3	TP53BP1	BRE	FAM175A	SUMO2	PIAS4	UBE2N	PARP1	SUMO1	UBE2I	HIST3H2BB	SIRT6	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	RNF4	HIST1H4K	HIST1H4L	POLQ	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	
TRANSPORT OF BILE SALTS AND ORGANIC ACIDS, METAL IONS AND AMINE COMPOUNDS%REACTOME DATABASE ID RELEASE 74%425366	Transport of bile salts and organic acids, metal ions and amine compounds	SLC22A5	SLC30A10	RSC1A1	EMB	CP	SLC39A10	SLC39A14	SLC39A6	SLC16A7	SLC39A5	SLC6A19	SLC39A8	SLC6A18	SLC39A7	SLC22A2	SLC39A2	SLC6A15	SLC39A1	SLC22A1	SLC39A3	SLC6A14	SLC6A13	SLC14A1	SLC6A12	SLC14A2	SLC6A11	SLC6A1	SLC6A2	SLC13A1	SLC6A3	SLC13A2	SLC16A8	SLC13A3	SLC6A5	SLC16A3	SLC13A4	SLC6A6	SLC6A7	SLC47A2	SLC6A9	SLC18A1	SLC47A1	SLC18A2	SLC13A5	SLC10A6	SLC22A18	SLC31A1	SLC30A3	SLC30A7	SLC30A2	SLC30A6	SLC30A8	SLC30A1	SLC30A5	SLC41A2	SLC41A1	SLC6A20	RHCG	RHBG	SLC39A4	SLC11A1	RUNX1	SLC16A1	RHAG	BSG	SLC2A13	SLC5A11	SLC5A3	SLC40A1	SLC22A4	SLC22A3	HEPH	SLC22A6	SLC22A15	SLC5A7	SLC44A5	SLC22A16	SLC22A12	SLC22A8	SLC44A3	SLC22A7	SLC44A4	SLC22A11	SLC44A1	SLC44A2	SLC11A2	
TRUNCATED APC MUTANTS DESTABILIZE THE DESTRUCTION COMPLEX%REACTOME DATABASE ID RELEASE 74%4839744	truncated APC mutants destabilize the destruction complex	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	PPP2R1B	AMER1	AXIN1	APC	
DEADENYLATION OF MRNA%REACTOME%R-HSA-429947.2	Deadenylation of mRNA	RQCD1	EIF4A2	EIF4A1	TNKS1BP1	CNOT6L	CNOT6	ZCCHC11	CNOT10	EIF4A3	CNOT4	CNOT7	PABPC1	CNOT1	PARN	CNOT11	CNOT2	CNOT3	CNOT8	ZCCHC6	PAN2	EIF4E	PAN3	EIF4B	EIF4G1	PAIP1	
REGULATION OF GENE EXPRESSION IN ENDOCRINE-COMMITTED (NEUROG3+) PROGENITOR CELLS%REACTOME%R-HSA-210746.1	Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	NKX2-2	NEUROD1	PAX4	NEUROG3	INSM1	
VITAMIN B2 (RIBOFLAVIN) METABOLISM%REACTOME DATABASE ID RELEASE 74%196843	Vitamin B2 (riboflavin) metabolism	SLC52A2	SLC52A3	ENPP1	SLC52A1	RFK	ACP5	FLAD1	
REGULATION OF APOPTOSIS%REACTOME DATABASE ID RELEASE 74%169911	Regulation of Apoptosis	PSMA6	PSMA3	PSMA4	PAK2	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	OMA1	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	OPA1	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	ARHGAP10	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
ADENYLATE CYCLASE ACTIVATING PATHWAY%REACTOME DATABASE ID RELEASE 74%170660	Adenylate cyclase activating pathway	ADCY2	ADCY1	ADCY8	ADCY7	ADCY9	GNAL	ADCY6	ADCY5	ADCY4	ADCY3	
COENZYME A BIOSYNTHESIS%REACTOME%R-HSA-196783.4	Coenzyme A biosynthesis	SLC25A16	PPCDC	PANK4	PANK2	PPCS	PANK3	PANK1	COASY	
GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION%REACTOME DATABASE ID RELEASE 74%162658	Golgi Cisternae Pericentriolar Stack Reorganization	USO1	MAPK1	PLK1	CDK1	GORASP2	BLZF1	GORASP1	CCNB2	GOLGA2	CCNB1	RAB1A	RAB2A	RAB1B	
ALPHA-DEFENSINS%REACTOME%R-HSA-1462054.1	Alpha-defensins	DEFA1B	PRSS3	CD4	ART1	DEFA6	DEFA4	DEFA5	PRSS2	DEFA3	DEFA1	
PHOSPHOLIPASE C-MEDIATED CASCADE; FGFR2%REACTOME%R-HSA-5654221.2	Phospholipase C-mediated cascade; FGFR2	FGF20	FGF1	FGF23	FGF2	FGF22	FGF3	FGF4	FGF16	FGF6	FGF7	FGF9	PLCG1	FGF18	FGF10	
SUMOYLATION OF IMMUNE RESPONSE PROTEINS%REACTOME DATABASE ID RELEASE 74%4755510	SUMOylation of immune response proteins	NFKBIA	SUMO1	NFKB2	RELA	UBE2I	SUMO3	PIAS4	PIAS3	IKBKG	TOPORS	IKBKE	
VRNP ASSEMBLY%REACTOME DATABASE ID RELEASE 74%192905	vRNP Assembly	HSP90AA1	IPO5	
DISSOLUTION OF FIBRIN CLOT%REACTOME%R-HSA-75205.2	Dissolution of Fibrin Clot	PLAU	PLAUR	SERPINB2	ANXA2	SERPINE1	SERPINB6	HRG	SERPINE2	SERPINF2	PLG	PLAT	SERPINB8	S100A10	
NEGATIVE REGULATION OF MET ACTIVITY%REACTOME%R-HSA-6807004.1	Negative regulation of MET activity	SH3KBP1	RPS27A	PTPRJ	STAM	HGS	USP8	LRIG1	EPS15	UBA52	SH3GL1	SH3GL3	STAM2	CBL	SH3GL2	PTPN2	UBB	PTPN1	HGF	UBC	MET	
INHIBITION OF HOST MRNA PROCESSING AND RNA SILENCING%REACTOME DATABASE ID RELEASE 74%168315	Inhibition of Host mRNA Processing and RNA Silencing	PABPN1	CPSF4	
PKB-MEDIATED EVENTS%REACTOME%R-HSA-109703.4	PKB-mediated events	PDE3B	AKT2	
RESISTANCE OF ERBB2 KD MUTANTS TO LAPATINIB%REACTOME DATABASE ID RELEASE 74%9665251	Resistance of ERBB2 KD mutants to lapatinib	ERBB2	HSP90AA1	CDC37	ERBB2IP	
SYNTHESIS OF IPS IN THE NUCLEUS%REACTOME DATABASE ID RELEASE 74%1855191	Synthesis of IPs in the nucleus	IPPK	IPMK	IP6K2	IP6K1	
METALLOPROTEASE DUBS%REACTOME%R-HSA-5689901.2	Metalloprotease DUBs	FAM175B	BABAM1	MYSM1	UIMC1	HIST1H2AJ	HIST2H2AC	STAM	BRCC3	UBA52	PSMD14	BRE	FAM175A	NLRP3	UBB	UBC	BRCA1	RPS27A	HIST2H2AB	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	HIST1H2AI	HIST1H2AH	HIST1H2AK	HIST3H2A	KAT2B	STAMBP	HIST1H2AE	BARD1	HIST1H2AD	EP300	STAMBPL1	HIST1H2AC	HIST2H2AA3	HIST1H2AB	HIST2H2AA4	
TRAF6 MEDIATED NF-KB ACTIVATION%REACTOME%R-HSA-933542.1	TRAF6 mediated NF-kB activation	MAP3K1	NFKB1	IFIH1	S100B	RNF135	TRAF2	NFKBIA	MAVS	SAA1	AGER	TRIM25	TRAF6	NFKBIB	S100A12	NFKB2	IKBKB	RELA	DDX58	HMGB1	APP	NKIRAS1	NKIRAS2	IKBKG	CHUK	
RUNX2 REGULATES BONE DEVELOPMENT%REACTOME%R-HSA-8941326.1	RUNX2 regulates bone development	YAP1	ZNF521	MAPK3	CBFB	SRC	COL1A1	HDAC6	HDAC4	ABL1	UCMA	SMAD4	SP7	SATB2	HEY1	IHH	HEY2	BGLAP	MAF	MAPK1	WWTR1	RBM14	YES1	RB1	AR	GLI3	GLI2	SMAD1	HDAC3	HES1	SMAD6	
FORMATION OF THE EDITOSOME%REACTOME DATABASE ID RELEASE 74%75094	Formation of the Editosome	APOBEC1	APOBEC3C	APOBEC2	APOBEC4	APOBEC3H	A1CF	APOBEC3A	APOBEC3B	
ORGANIC CATION TRANSPORT%REACTOME DATABASE ID RELEASE 74%549127	Organic cation transport	SLC22A15	SLC22A16	SLC22A2	SLC22A5	SLC22A1	RSC1A1	SLC22A18	SLC22A4	SLC22A3	RUNX1	
CARGO CONCENTRATION IN THE ER%REACTOME%R-HSA-5694530.1	Cargo concentration in the ER	MIA3	LMAN1	AREG	CTSC	SEC23A	LMAN2	PREB	CD59	TMED10	SEC24B	COL7A1	SEC24A	GRIA1	FOLR1	SEC22B	SEC24D	SEC24C	LMAN1L	GOSR2	LMAN2L	SERPINA1	CNIH1	TGFA	STX5	F5	TMED2	CNIH2	SAR1B	F8	CNIH3	MCFD2	CTSZ	MIA2	
SIGNALING PATHWAYS%REACTOME DATABASE ID RELEASE 74%162582	Signaling Pathways	OR11A1	OR8A1	OR8I2	OR52N1	RRH	OR52N5	ABCG8	OR52N4	ABCG5	OR52N2	EDNRA	OR5D18	CFTR	EDNRB	ABCG1	VCP	OR10W1	OR2A42	OR5D16	OR5D14	OR5D13	OR8H3	OR8H2	SEL1L	UTS2R	OR8H1	GPR37L1	OR52M1	UTS2B	OR10V1	ABCA4	OR4C12	OR6C6	OR4C11	OR6C4	OR6C3	OR4C16	OR8G5	OR6C2	OR4C15	OR5AK2	OR6C1	OR4C13	OR8G1	OR10T2	OR52L1	KDM3A	KDM1B	NLN	PPY	KDM4A	ARL4C	OR6B3	EEPD1	OR6B2	OR6B1	PDYN	NTSR1	APOA1	CCR10	NTSR2	OR2A25	NMB	XCR1	DERL2	PDE2A	OR10S1	ERLEC1	NMBR	OS9	OR52K2	OR52K1	NMS	NMU	PDE3A	IER3	OR2A12	PIP5K1A	OR6A2	PIP5K1B	OR2A14	SNAI1	OR2A1	SNAI2	OR4E2	STRN	CX3CL1	MECOM	BRS3	PHLPP2	CCKAR	PHLPP1	FFAR3	ATN1	OR4D9	MAF1	FFAR2	OR5AP2	TRAT1	PIK3AP1	OR5B12	OR4D6	OR4D5	OR5B17	OR4D2	USP8	OR4D1	EDN1	RNF41	EDN2	EDN3	OR10Z1	CCKBR	OR52R1	OR4C6	OR4C5	OR4A15	OR4C3	OR4A16	OR8K5	NPB	OR8K3	OR8K1	POLR2A	CXCR5	POLR2B	CXCR6	POLR2C	CXCR1	NPW	POLR2D	CXCR3	CXCR2	POLR2E	KISS1R	POLR2F	OR5AN1	OR4B1	POLR2G	OR4C46	POLR2H	OR6F1	POLR2I	OR8J3	POLR2J	OR8J1	OR10X1	POLR2K	F2RL1	POLR2L	OR4A5	CCL4L2	PMCH	NPY2R	OR6M1	OR2T12	OR2T10	OR2T11	OR5H15	OR5H14	PDE8B	PDE8A	GHSR	OR2D3	OR2D2	OR52E4	OR52E2	NPY1R	OR5AC2	APLNR	OR52E8	OR52E6	OR52E5	OR2C3	OR6K6	OR2C1	SUCNR1	OR6K3	OR6K2	OR52D1	NTS	OR2B6	OR4F6	OR2B3	OR4F5	OR2B2	OR10K2	OR4F4	OR4F3	YWHAB	OR10K1	OPN4	HSPB1	OPN3	XPO1	OR6J1	OPN5	PYY	NMUR2	PRKCD	NMUR1	YWHAZ	OR2A7	OR2A5	MAPKAPK2	OR2A4	OR2A2	TAS2R7	GPSM1	CXCL6	GPSM2	TAS2R9	CXCL9	OR52J3	TAS2R8	MLNR	OR4M2	OR4M1	OR10R2	PSAP	CXCL3	CYFIP2	OR6Q1	NCKAP1	CXCL5	OR8U1	MAPK14	CYFIP1	WIPF1	MAPK11	BDKRB2	IGF2	ARPC1B	BDKRB1	IGF1	WIPF2	EIF4G1	TAS2R1	PPBP	ARPC1A	TAS2R3	WIPF3	TAS2R5	GPSM3	BRK1	WASL	TAS2R4	ACTB	OR52I2	ACTG1	OR52I1	NCK1	NPY5R	ACTR3	OR2H2	VAV3	OR2H1	ACTR2	OR4L1	VAV2	OR6P1	OR10Q1	CORT	ELMO1	BTK	RGS18	ELMO2	OR2G6	WAS	RGS17	NCKIPSD	OR52H1	NCKAP1L	RGS19	WASF1	OR2G3	OR4K5	WASF2	WASF3	RGS14	NPY4R	OR2G2	ARPC4	RGS13	MYO9B	RGS16	ARPC5	OR4K2	BAIAP2	OPRL1	OR4K1	ABI2	OR10P1	ARPC2	OR2T34	ARPC3	OR8S1	OR2T35	ABI1	OR2T33	PDE11A	RGS21	RGS20	S1PR3	S1PR2	RGS22	S1PR5	S1PR4	OR2T27	OR2F2	OR2F1	OR2T29	IFT172	OR6N2	PRKACG	OR6N1	PRKACB	KISS1	DYNC2H1	PDE10A	RPGRIP1L	RGS10	RBX1	RGS12	IFT88	PDE7B	ADCY9	PDE7A	PRKAR1B	SMO	PRKAR1A	GPR161	INTU	KIF3A	PRKAR2A	TTC21B	PTCH1	IFT122	FUZ	ADCY10	GNAS	MKS1	GLI1	GLI3	GLI2	IFT52	SUFU	UGT1A3	IFT57	IFT140	KIF7	WDR35	NUMB	ADCY4	TULP3	ADCY3	ADCY2	OXTR	ADCY1	AVPR1B	OXT	ADCY8	ADCY7	AVPR1A	ADCY6	STAM	ADCY5	CSNK1A1	HGS	HHAT	WDR19	ITCH	STAM2	PDK4	PDK3	PDK2	PDK1	KLK3	KDM4C	PKN1	DLD	IL1RL1	IL33	PIK3R6	CDKN1A	CDKN1B	CHEK1	RUVBL1	MDM2	ATF1	APP	ATF2	FASN	UBE2D3	ELK1	MEF2A	MEF2C	VRK3	MAPKAPK3	S100A9	S100A8	SOCS1	IRAK1	KIF5B	JUN	KIF5A	AR	MYD88	DUSP3	RIPK2	DYNC1LI1	IRAK4	DYNC1LI2	FOS	ZW10	DNM1	DNM2	DNM3	FABP5	FABP6	KLC1	HEY1	BIRC2	KLC4	HEY2	KLC3	KLC2	BIRC3	NRIP1	RACGAP1	RING1	RAB6A	MAPK8	MAPK7	S100B	KIF18A	PPARD	SAA1	ZDHHC7	CRABP2	ERBB2IP	GREB1	NR5A2	TFF1	KANK1	ZDHHC21	ZNF217	EBAG9	CLIP1	FOXA1	CTNNA1	PPID	IQGAP2	CAV2	IQGAP3	CHD1	MEN1	CXXC5	USF2	USF1	USP9X	SCD	SKI	TMED2	WWOX	CITED1	DYNLL2	KIF2A	KIF2C	KIF2B	GPNMB	LRRK2	FOXO6	FOXO4	GSK3A	DYNC1I1	CENPE	BDNF	SP1	SYVN1	SST	TRIM33	BMI1	RXRB	RXRG	DNER	TLE4	TLE2	TLE1	GNGT1	PPP3CA	DTX1	PPP3CB	DTX2	GNGT2	DLK1	GNAT2	CAV1	PRKG2	PRKG1	BMP2	WNT5A	TGIF1	PLCB3	PLCB1	TGIF2	PLCB2	CAMK2A	LEF1	TCF7	RNF2	ITPR1	ITPR2	ITPR3	SERPINE1	NLK	GNG3	GNG10	JUNB	PPP3R1	GNG2	ST3GAL6	ADH1C	RNF111	ADH1A	WNT11	CRABP1	GNG5	GNG4	DHRS4	GNG7	ALDH1A3	CYP26A1	GNG8	ADH4	PDE6B	SDR16C5	PDE6A	CYP26B1	TCF7L2	CYP26C1	FZD3	ALDH1A2	TCF7L1	ALDH1A1	FZD2	RDH14	FZD5	RDH13	PHC2	PDE6G	ALDH8A1	FZD4	FZD6	PHC1	NFATC1	AAMP	FOXO1	GNG12	GNG11	GNG13	GNAO1	TNRC6C	MOV10	AGO3	AGO4	PHC3	GNB2	AGO1	GNB1	AGO2	GNB4	GNB3	RSPO3	CTNNB1	GNB5	TNRC6A	TNRC6B	SRF	FOXO3	UHMK1	TNKS2	TNKS	WWP1	BMP10	ARHGEF11	ARHGEF12	ROCK1	ROCK2	LIMK2	LIMK1	RHOC	RHOA	MYL12B	CDC14A	RHOB	PGR	GRB7	MYL6	ERBB2	MYH9	MYH14	MYH11	PLXNB1	FKBP5	MYH10	MKNK1	MYL9	SPRY2	BAD	PPP3CC	YWHAQ	BCL2	SFN	YWHAH	SKIL	BCR	BAG4	STAT1	STAT3	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	HDAC4	HDAC5	SHC1	HDAC8	EGF	GAB1	HDAC9	CBL	HDAC7	EGFR	NRAS	CDC37	PLCG1	SOS1	HRAS	HDAC10	HDAC11	FIGF	FLT1	FLT4	VEGFB	KDR	VEGFC	SOX9	PGF	RUNX3	VEGFA	NPY	TJP1	ATP1B4	KCTD6	CBX8	SMAD1	CBX6	CBX4	CBX2	SMAD6	ESR2	NR4A1	NR2E1	OPRM1	THBS1	OPRK1	SH3GL3	ARC	TRIB1	TPH1	RRAD	MAP2K5	EGR1	JUND	EGR3	EGR4	FOSL1	ID2	ID1	ID4	ID3	DNAL4	LYL1	VGF	RALA	RALB	ASCL1	KIDINS220	RIT1	RIT2	FOSB	CDK5R2	FGFBP1	FGFBP2	FGFBP3	SRMS	PTK6	CDC73	LEO1	WWC1	YBX1	DLGAP5	RPS6	PTCRA	HEYL	FABP7	EIF4EBP1	RPS27	NMT1	NMT2	EIF4E	EIF4B	PTPRS	IRS1	SRC	NTRK3	PTPRO	NTF3	BAX	NELFB	SMAD2	SMAD3	TGFB1	TGFBR1	NCF1	TGFBR2	NCF2	NCF4	RAC2	NOS3	CYBB	NOTCH2	MAML2	MAML1	PSEN2	RBPJ	DLL1	DLL4	APH1A	NEURL1B	APH1B	MDK	EP300	HES1	HES5	JAG2	PSENEN	JAG1	MIB2	GZMB	MIB1	FCER2	CREB1	NEURL1	CNTN1	MAML3	MAMLD1	MUC20	ARHGAP10	TJP2	PTGFR	TBXA2R	PTGDR2	GUCA1B	PTGER1	GUCA1A	PTGER3	GUCA1C	CNGA1	CAMKMT	RBP2	RGS9BP	SAG	PPEF1	GUCY2D	RETSAT	GUCY2F	LRP8	GRK1	APOM	GRK7	BCO2	BCO1	RCVRN	AKR1C1	AKR1C4	AKR1B10	LRP10	METAP1	LRP12	METAP2	NCBP1	CPT1A	NCBP2	AGT	PAG1	STAT6	CPT1B	KPNA2	GTF2F1	GTF2F2	CLTC	CLTA	PARP1	SPTAN1	SPTB	SPTBN4	SPTBN5	INS	SPTA1	CD55	SPTBN1	SPTBN2	ITSN1	PDHX	UBE2D1	NGEF	PIP5K1C	JUP	CCNE1	PBX1	EZH2	NF2	DLAT	CDK2	PPARG	ATP2A3	MEF2D	ATP2A2	ATP2A1	AGRN	NAB1	NAB2	PDHA2	PDHA1	YY1	MAG	KMT2D	PDHB	DRAP1	CXCL12	HSP90AB1	NCK2	ITGAV	ITGA2	MEMO1	DIAPH1	E2F1	CCNC	CER1	KDM4B	TRAF6	PRKCQ	FOXH1	RASGRP2	RASGRP1	RASGRP4	LYN	TAB3	TAB2	TAB1	EPAS1	SDC2	KALRN	PCK1	WWTR1	EGR2	SMARCA4	SNW1	NRP1	NRP2	NCOA1	NCOA2	NCOA3	ARHGEF7	TRADD	YAP1	TNFRSF10B	RXRA	TRAF2	TNFRSF10A	FASLG	GPC1	CASP8	TNFSF10	IGF2BP1	FAS	RIPK1	FADD	CCND3	ITGB1	IL6R	SH3GL2	FN1	DOK1	DLG1	DLG3	DLG4	CREBBP	PAK1	EED	RPS6KA5	PAK3	RAF1	PAK2	LAMA2	LAMA1	ACVR1B	ACVR1C	CCNT1	ACVR2B	ACVR2A	MAPK13	CARM1	RAG2	TRIO	RAG1	MYC	NTF4	CDK9	MED1	SFPQ	KHDRBS1	KHDRBS2	KHDRBS3	STAP2	HNRNPM	HNRNPF	RFNG	POGLUT1	POFUT1	MFNG	ACTA2	HNRNPH1	FLRT3	PRKAA1	PRKAA2	CAB39	RARG	CAB39L	PRKAG1	CLTB	PRKAG2	ASH2L	PRKAG3	RPTOR	STK11	EEF2K	SLC38A9	PRKAB2	STRADA	STRADB	TSC2	TCF12	TSC1	PRKAB1	FKBP1A	NCOR2	PPM1A	NCOR1	RRAGA	RRAGC	RPS6KB1	RARA	RRAGB	RARB	RHEB	PLIN1	AKT1S1	RRAGD	LAMTOR2	LAMTOR1	LAMTOR4	DDX5	LAMTOR3	LAMTOR5	PLXND1	TNF	PTBP1	SALL4	CFL1	GRB10	FST	INHBB	INHBA	FSTL3	CBFB	HNRNPA1	SRGAP3	SRGAP1	CDK8	POU2F1	TRPC7	TBP	TRPC6	TRPC3	ANOS1	TFDP1	TFDP2	EVL	SOS2	HDAC3	RBBP5	MATK	LEP	IGF1R	SOX2	CDON	RUNX1	KNG1	TIAM1	PDE4B	PDE4A	PDE4D	PFN1	PDE4C	PPP1R1B	PFN2	FGB	FGA	VWF	F2R	FGG	F2	F3	ADAM12	PF4	SH3KBP1	PTPRU	SOCS6	FER	GRAP	CXCR4	TBL1X	SUZ12	STAT5A	STAT5B	EPO	PIK3CD	IRS2	SLC24A1	PIK3CB	CDK5R1	PIK3CG	VAV1	ARHGAP39	EPOR	ARHGAP35	PIK3R5	CRKL	RAPGEF1	PLCG2	JAK2	TBL1XR1	NPHP4	SMAD4	RPS6KB2	FES	CLASP2	NOX3	DAAM1	SCAI	DIAPH3	MKL1	FMNL3	FMNL1	FMNL2	CTNND1	F11R	CDH5	PARD3	CCR5	CUL5	PARD6A	P2RY12	ARAF	WDR83	SYNGAP1	GOLGA7	ACTN2	PAQR3	FLT3LG	FRS2	FRS3	EREG	BTC	TLN1	PIK3R4	PDGFB	ERCC6L	TGFA	ZWILCH	CASC5	IQGAP1	SMC3	RCE1	RALGDS	KNTC1	BRAP	MAD1L1	ICMT	CDCA8	BRAF	GRIN2B	PTK2	PMF1	GRIN2D	SKA1	PPP5C	ARTN	SKA2	DSN1	RGL3	RGL1	RAD21	RCC2	RGL2	NDC80	RET	AREG	ZWINT	PEA15	STAG1	NEFL	STAG2	JAK3	AHCTF1	JAK1	SGOL2	DUSP4	SGOL1	DUSP5	NUF2	LYPLA1	DUSP2	SPDL1	DUSP1	NDEL1	GFRA1	NUDC	ITGA3	GAB2	RANGAP1	DUSP8	SMC1A	INCENP	GFRA3	BIRC5	IL17RD	DUSP9	ITGB3BP	GFRA2	MIS12	DUSP6	CENPA	DUSP7	AURKB	NSL1	GFRA4	CENPC	CNKSR2	APBB1IP	BUB1	CENPT	CENPU	CNKSR1	CENPF	MRAS	PTPN12	LRRC7	APITD1	CENPH	KIT	CENPI	TLR9	RAPGEF2	TAOK1	CENPK	HBEGF	CENPL	SHOC2	DAB2IP	CENPM	CENPN	RANBP9	CENPO	USP17L2	GRIN1	B9D2	CENPP	EPGN	CENPQ	ZDHHC9	KBTBD7	SPC24	KLB	SPC25	CSF2	ITGA2B	PEBP1	IL5RA	FGF1	FGF2	FGF3	FGF4	PPP1CC	FGF6	FGF7	FNTA	FGF9	FNTB	NRTN	XIAP	PDGFRB	PDGFRA	MAP2K1	CASP9	MAP2K2	HGF	VCL	SHC2	SHC3	GABBR2	CUL3	ARL2	GABBR1	CSF2RB	RASAL1	PHB	RASAL2	RASAL3	CSF2RA	RASGRP3	RAP1B	RAP1A	FGF20	PPP1R15A	MARK3	USP15	FGF23	NEDD4L	FGF22	MTMR4	PMEPA1	PSPN	IL2	SMURF2	FGF16	SMURF1	IL3	UCHL5	PPP1CA	IL5	SMAD7	DLG2	BAMBI	GDNF	PTPRA	STRAP	STUB1	FGF19	FGF18	UBE2M	NF1	FGFR4	GALNT3	MAP3K11	BCL2L1	FGF10	FLRT2	FLRT1	FLT3	ITGB3	RASGRF2	PML	PDE3B	RASGRF1	ARRB1	FSTL1	ARRB2	DUSP16	SPRED3	SPRED2	SPRED1	HEBP1	ANXA1	DUSP10	RASGEF1A	FPR1	PPP2R5E	FPR3	FPR2	KSR1	PPP2R5B	PPP2R5A	PPP2R5D	NRG1	PPP2R5C	KSR2	NRG2	CCL11	RASA3	SNX3	NRG3	RASA4	AKR1C3	CCL19	NRG4	RASA1	CHRDL1	CCL22	IL3RA	RASA2	CCL20	PIK3C3	MET	CAMK2B	CAMK2D	ABHD17C	IL2RG	PDE6D	CSK	NCAM1	CAMK2G	ANGPT1	PTPN11	MAPK12	CGN	ABHD17B	PRKCZ	ABHD17A	IL2RA	IL2RB	EPS15	KRAS	CXCL10	TEK	SH3GL1	PTPN7	PRMT1	CDC25C	CCL5	PTPN3	CCL4	RBL1	CCL3	E2F4	OPN1SW	OPN1MW	OPN1LW	RBP3	OPN1MW2	CCR1	DHRS3	RLBP1	KTN1	NOTUM	CCR2	OPRD1	CCL3L1	CCL3L3	CXCL1	CXCL2	PTK2B	ZRANB1	C3	LFNG	GPR17	P2RY13	P2RY10	P2RY14	LPAR4	P2RY6	P2RY4	LPAR6	P2RY2	ADORA3	P2RY1	THBS2	ADORA1	PXN	PRDM4	SPPL2B	SPPL2A	PREX1	ARHGDIA	ARHGEF40	PRKCI	USP4	USP2	OMG	CLIP3	HHIP	TIAM2	BOC	NGFRAP1	GAS1	OBSCN	RBCK1	SQSTM1	NSMAF	ARHGEF26	MAGED1	RTN4	ABR	BCL2L11	SHARPIN	ECT2	ARHGEF33	NGFR	ARHGEF35	ARHGEF37	ARHGEF39	RGS9	ARHGEF38	RGS6	GNB2L1	TNFRSF10D	RGS7	NET1	CYLD	TNFAIP3	OTUD7B	ARHGEF10L	SPHK1	AATF	SMPD3	SMPD2	AKAP13	CASP10	MCF2L	CASP2	ARHGEF10	PLEKHG2	ARHGEF15	PLEKHG5	ARHGEF17	ARHGEF16	ARHGEF19	SSTR3	MCHR1	ARHGEF18	TRAF1	NGF	TNFRSF1A	ARHGEF9	TAX1BP1	ARHGEF3	RGS11	ARHGEF4	ARHGEF1	ARHGEF2	ARHGEF5	ARHGEF6	RNF31	FGD1	FGD2	GNA13	FGD3	FGD4	LINGO1	USP21	MCF2	CFLAR	OTULIN	GRP	FFAR4	FFAR1	SCRIB	PRICKLE1	VANGL2	GTF2A1	GTF2A2	LAMC3	LAMA4	LAMB2	TERT	MYLK	NPFFR2	NPFFR1	NPFF	QRFPR	HCRT	QRFP	HCRTR2	HCRTR1	ROPN1	TAX1BP3	PKN3	GOPC	PKN2	RTKN	RHPN1	RHPN2	PPP1R14A	GNA14	GNA15	GNA11	GNA12	GNAQ	F2RL2	F2RL3	NTRK1	ADORA2A	KDM1A	MYB	CTBP1	CHD8	TP53	CBY1	SOX3	SOX17	SRY	SOX6	SOX7	SOX4	GATA3	BCL9L	TLE3	CTNNBIP1	SOX13	PYGO1	PYGO2	ABL1	BCL9	CDK5	DOCK3	DOCK7	RAC1	DOCK1	HDAC2	HDAC1	CDC42	SH2B3	PTPN1	SYK	CSNK1G2	CRK	RAPGEF3	BCAR1	RAPGEF4	PTPRJ	SPINT2	TNS4	TNS3	HGFAC	SPINT1	HPN	LRIG1	RAB4B	RANBP10	AGTR1	RXFP1	RXFP2	GPR176	AP2A1	GNAT3	C3AR1	PTGDR	PCSK6	AP2A2	LHB	PCSK5	CRHR2	MC2R	CGA	AP2M1	GPR15	MC1R	MYLIP	NOX1	APOA2	GPR27	GPR25	TRRAP	APOA4	FRAT1	GPR20	MC4R	FRAT2	GPR39	DKK1	FSHB	DKK2	GPR32	DKK4	SFRP1	ANGPTL3	GPBAR1	SFRP2	MC3R	HECW1	CCDC88C	EPS15L1	RSPO2	CETP	FSHR	RSPO1	TACR1	RSPO4	NPSR1	PTGER4	KREMEN1	GPR45	KREMEN2	PTGER2	WIF1	LPL	LGR6	GNAI3	LGR5	NOXO1	LGR4	GNAI1	ARF6	GNAI2	AP2S1	RNF43	KLHL12	NPS	APOE	USP34	APOB	GPR150	SOST	DACT1	LDLR	GGA3	GPHA2	ADRBK2	AXIN2	P2RY11	MC5R	GPIHBP1	LRP5	ABCA1	LRP6	GPHB5	ZNRF3	NR1H2	CYSLTR1	APOC4	LHCGR	APOC3	CYBA	NR1H3	AP2B1	GNAZ	APOC2	GPR83	APOC1	GPR84	CTBP2	DVL1	P4HB	DVL2	AES	DVL3	NOXA1	RLN2	RLN3	INSL3	RAB4A	TSHB	PTGIR	AVPR2	YWHAE	ADORA2B	TSHR	PPP1CB	POMC	PPP2R1A	PRKACA	BTRC	YWHAG	SKP1	OFD1	HSP90AA1	PPP1R12A	CLPS	PNLIP	PTPRK	SPRY1	CSNK1E	DYNLL1	CKAP5	LRP1	LRP2	MAPRE1	UBA52	PAFAH1B1	DYNC1I2	CUL1	AMHR2	ZFYVE16	GDF2	UBB	SMAD9	SMAD5	BMPR1B	BMPR1A	PRKAR2B	UBC	SPARC	ACVRL1	BMPR2	AMH	NOG	GREM2	RPS27A	CLASP1	DYNC1H1	NDE1	PLK1	CDK1	MST1R	GDI1	GDI2	CCNK	CXCL8	CCL2	PIP4K2A	PIP4K2B	PIP4K2C	CTTN	RHOQ	TRIP10	BUB1B	CDC20	BUB3	MAD2L1	OCRL	IL6	SGK1	CCNT2	USP7	MAPKAPK5	EPN1	PIN1	ST3GAL4	PTEN	ST3GAL3	PLB1	C5AR2	FKBP4	C5AR1	CSNK2A1	C5	HDAC6	CSNK2A2	DNAJB1	CD19	CSNK2B	PTGES3	AVP	PLAT	THBS4	THBS3	PDGFD	FGFRL1	PREX2	TRIM27	USP13	WWP2	RNF146	NEDD4	MKRN1	FRK	OTUD3	PLA2G4A	MGLL	AWAT2	LIN7B	CAMKK1	CAMKK2	NBEA	CAMK4	GPAM	STMN1	SDC4	RBFOX2	CILP	SHB	SDC3	GPC3	IRS4	SDC1	TIA1	GPC2	ADAP1	GFAP	GPC5	GPC4	ESRP2	CSN2	GPC6	TIAL1	SH2D2A	AXL	MXD4	WNT5B	ROR1	ROR2	ESRP1	GRAP2	GABRG3	GABRG2	GABRB3	GABRB2	GABRB1	GABRQ	GABRA1	GNAL	EVC2	IQCE	EFCAB7	EVC	GAS8	PORCN	AHCYL1	PRKX	YES1	NUP107	PPP2R1B	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	CDC42EP5	CDC42EP3	CDC42EP2	CDC14B	PRKCB	SEPT7	ETV4	HIST1H2AJ	MAPK6	PRKCA	MAPK4	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	PTPN18	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	PTPN2	H2AFB1	CHD4	CHD3	HIST1H3J	NUP160	MTA1	HIST1H3A	NUP85	RBBP4	HIST1H3F	HIST1H3G	HIST1H3H	RBBP7	HIST1H3I	MTA2	HIST1H3B	MTA3	SCUBE2	HIST1H3C	MBD3	DISP2	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	GATAD2B	HIST1H4L	GATAD2A	KAT2B	H3F3A	KAT2A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	TEC	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	HIST2H2AC	H2AFJ	SEC13	DTX4	NUP133	H2AFZ	H2AFX	PELP1	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	PPP2CA	HIST2H4A	PPP2CB	HIST2H4B	MAPK1	NUP43	RANBP2	HIST3H3	NUP37	B4GALT1	GLP1R	UCN	VIPR1	WNT2B	VIPR2	SCT	IHH	ADM	PTH1R	FZD10	ADGRE1	ADGRE2	CRHBP	SHH	CYSLTR2	ADGRE5	UCN3	UCN2	ADGRE3	GLP2R	WNT9B	PTH2R	WNT9A	WNT16	GIP	ADCYAP1	CRH	IAPP	CALCA	RAMP2	RHO	ADCYAP1R1	RAMP3	CALCRL	CALCB	DHH	GIPR	WLS	PTH	DZIP1	WNT8A	PSMD8	WNT8B	SPOP	IKBKB	PTH2	AMOTL2	PSMD9	CNGB1	AMOTL1	PSMD6	PTHLH	VPS29	CRHR1	PSMD7	VPS35	OR2M7	PSMD4	GHRHR	TMED5	OR2M5	PSMD5	WNT6	OR2M4	PSMD2	SAV1	CALCR	AMER1	OR2M3	PSMD3	ULK3	WNT1	HIF1A	AXIN1	OR4K17	PSMD1	WNT2	SPOPL	OR2M2	IKBKG	WNT3	VPS26A	APC	OR4Q3	MAP3K7	WNT4	MOB1B	OR2L8	FZD1	MOB1A	CHUK	OR2L5	PSMA5	WNT10B	STK4	OR2L3	PSMA6	WNT10A	STK3	OR4P4	WNT3A	PSMA3	KIF14	LATS1	CIT	OR2L2	PSMA4	FZD7	LATS2	WNT7B	OR10AD1	PSMA1	PRC1	OR6T1	PSMA2	PPP1R12B	PTCH2	OR4K15	PSME3	FZD9	SCTR	OR4K14	PSME4	OR4K13	PSME1	FZD8	AGTR2	WNT7A	PSME2	GCG	OR2K2	ADM2	OR6S1	PSMD10	NPBWR1	PSMB11	GHRH	NPBWR2	PSMD12	VIP	OR10D3	RAMP1	PSMD11	OR8B12	PSMD14	OR14K1	PSMD13	NOTCH1	OR4N5	PSMB10	OR2J3	OR4N4	OR2J2	PSMA7	E2F5	RELA	OR2J1	OR4N2	PSMA8	OR10C1	PSMB6	GPR18	PSMB7	OR10J1	PSMB4	OR10J3	PSMB5	OR10J5	PSMB2	GPRC6A	PSMB3	OR6Y1	PSMB1	OR52B2	PSMF1	OR52B6	SHFM1	GPR37	PSMB8	GPR35	NFKB1	GPR31	PSMB9	OR6X1	NFKBIA	OR52A1	PSMC5	OR52A5	PSMC6	OR10H1	PSMC3	OR10H3	PSMC4	OR10H2	PSMC1	OR10H5	PSMC2	OR10H4	OR4S2	OR4S1	PROKR1	PROKR2	OR10G2	OR14A16	OR10G4	GPR55	OR10G3	OR6V1	OR10G6	OR10G8	OR10G7	OR10G9	GPR68	ESR1	GPR65	APOD	CXCL13	CXCL16	OR14C36	OR2T8	OR2T7	SIRT6	OR2T6	ELF3	OR2T5	OR2T4	NOTCH3	OR2T3	NOTCH4	E2F3	OR2T2	OR2T1	OR4X2	OR4X1	OR9A4	OR51T1	OR9A2	UTS2	OR2S2	OR51S1	CXCL11	OR7E24	SOCS3	OR7A10	OR14J1	ECE1	OR2Y1	PTPN6	PRR5	OR56B1	CD86	PRLHR	PDPK1	OR56B4	MAPKAP1	OR7A17	CD80	OR14I1	PIK3R3	OR10A7	PIK3R2	OR56A5	PIK3R1	MTOR	OR7A5	PIK3CA	OR10A2	OR56A4	LCK	AKT2	OR10A4	GPS2	AKT3	OR10A3	OR56A3	MLST8	OR10A6	CD28	THEM4	OR10A5	AKT1	OR56A1	TRIB3	CCL7	OR2W3	FYN	OR2W1	RICTOR	CCL1	OR12D3	OR12D2	APLN	OR51V1	OR2V2	GSK3B	OR2V1	CCND1	OR7G2	CDK4	TCIRG1	OR7G1	OR9K2	TAS2R20	RGSL1	OR51L1	ATP6V1E1	ATP6V1E2	OXER1	OR5B3	ATP6V0B	OR5B2	ATP6V1G1	ATP6V0E1	TAS2R10	ATP6V1G2	TAS2R13	TAS2R14	ATP6AP1	TAS2R16	TAS2R19	KEL	OR2AT4	ATP6V1B2	OR5A2	ATP6V0D1	OR5A1	OR9I1	TACC3	ATP6V0D2	TAS2R40	ATP6V0C	ATP6V1B1	TAS2R41	TAS2R42	TAS2R43	LPAR1	ATP6V1A	TAS2R46	LPAR2	NEDD8	LPAR3	OR51J1	ATP6V0A2	PENK	OR7D4	ATP6V1H	OR7D2	ATP6V0A4	TAS2R30	OR51I2	ATP6V1G3	ATP6V0E2	TAS2R31	TAS2R38	GNAT1	ATP6V1D	ATP6V1C1	PRKCG	TAS2R39	OR51I1	PLCB4	ATP6V1C2	LPAR5	PDE1C	GNRH2	ATP6V0A1	PDE1B	OR4D11	PDE1A	ATP6V1F	GNRH1	ADRBK1	OR4D10	OR2Z1	OR9G4	OR7C2	OR7C1	OR9G1	TAS2R60	MLN	OR51Q1	CDKN2B	GNRHR	CCR9	CCR8	INSR	CCR7	CCR6	CCR4	CCR3	OXGR1	TAS2R50	OR5F1	GAL	OR3A3	OR14A2	OR3A2	OR3A1	PRLH	OR51M1	XK	OR5C1	OR7G3	OR1C1	OR5K4	OR5K3	SDR9C7	MYO7A	OR5K2	HSD17B6	OR51D1	OR5K1	RPE65	RBP4	RGS4	TTR	RGS5	RDH12	RGS2	DHRS9	RGS3	RDH11	RGS1	CCRL2	CYP4V2	RDH10	RGS8	HSD17B1	CASR	OR1B1	RBP1	OR5J2	NAPEPLD	RDH16	PCP2	PTAFR	OR1A2	RDH5	OR1A1	LRAT	OR51B2	FLNA	STRA6	ARHGEF25	OR5I1	OR9Q2	COL4A2	OR9Q1	MCHR2	COL4A1	COL6A2	HCAR2	HCAR3	COL4A4	OR2AK2	HCAR1	GRK5	COL4A3	GRK6	OR51B6	COL6A1	OR51B5	TAC3	OR51B4	TAC1	OR5H6	COL6A3	OR5H2	COL4A5	OR5H1	OR2AJ1	COL6A6	OR51A4	COL6A5	OR51A2	OR51A7	RTP4	NTRK2	RTP5	RTP2	OR51H1	RTP3	RTP1	OR1G1	OR10AG1	GRM1	CDH1	LTB4R	GRM3	GRM2	GRM5	GRM4	GRM7	GRM6	GPER1	GRM8	OR51G2	OR51G1	OR1F1	ADAM10	SSTR1	HSPG2	SSTR2	SSTR4	ADAM17	SSTR5	OR2AP1	OR2B11	OR51F2	DGKG	OR51F1	DGKE	OR5M9	DGKD	OR5M8	DAGLA	OR1E2	DGKB	OR1E1	PSEN1	DGKA	OR5M3	ABHD6	KLK2	OR5M1	ABHD12	CNR2	PRKCH	CNR1	PRKCE	OR4F29	DGKZ	NCSTN	TAS1R2	DGKQ	TAS1R1	DAGLB	TAS1R3	DGKK	A2M	OR4F21	DGKI	OR51E1	DGKH	OR1D5	OR1D2	COL9A1	OR51E2	COL9A3	OR5L2	COL9A2	OR5L1	CCK	LAMC2	OR4F17	LAMC1	OR4F16	OR4F15	CHRM2	ACKR4	CHRM3	ACKR3	CHRM1	ACKR2	CHRM4	ACKR1	CHRM5	HTR2B	OR11H2	HTR2C	OR11H1	OR11H4	ADRA1D	RXFP4	ADRB1	HTR2A	CASP3	OR1K1	GRPR	ADRB2	RXFP3	ADRA1B	HTR4	OR2AE1	OR11H6	ADRA1A	PROK2	HRH1	HTR6	PROK1	HTR7	CMKLR1	CTSD	HRH3	OR1J4	HRH2	OR11G2	HRH4	MMP7	OR1J2	DRD1	OR1J1	DRD2	OR5R1	DRD3	MMP2	TRHR	OR13J1	DRD4	MMP3	DRD5	OR1I1	TAAR8	OR5M11	MMP9	HTR1E	OR5M10	TAAR9	GALR3	HTR1F	GALR2	TAAR6	GALR1	HTR1D	OR5P3	HTR1A	OR5P2	HTR1B	GPR183	TAAR5	PNOC	TAAR2	OR11L1	GPR132	ADRA2C	HTR5A	OR5W2	TAAR1	GAST	FAM13B	LAMA5	FAM13A	TACR2	ADRA2A	ARHGDIG	TACR3	GPR143	LAMA3	OR1N2	ADRB3	ARHGAP36	PLG	OR1N1	SYDE2	FURIN	OR5V1	ARHGAP44	RGR	SYDE1	CCL13	ARHGAP42	SPP1	OPHN1	OR1M1	OR2AG1	ARHGAP40	ARHGDIB	LAMB3	OR2AG2	RALBP1	CCL17	CMA1	STARD8	LAMB1	CCL16	HMHA1	CCL25	DEPDC1B	CCL21	OR1L8	ARHGAP19	NR3C1	OR1L6	ARHGAP18	OR1L4	ARHGAP17	GPR4	ARHGAP15	OR1L3	RHOBTB1	OR1L1	ARHGAP12	OR5T3	RHOBTB2	TYK2	OR5T2	ARHGAP22	KAT5	OR5T1	INPP5B	CCL28	ARHGAP21	CCL27	ARHGAP20	RHOT2	OR52W1	RHOT1	OR1S2	STARD13	OR1S1	OR13D1	ARHGAP29	OR5AS1	ARHGAP28	MTNR1A	ARHGAP27	OR13C9	ARHGAP26	S1PR1	OR13C8	ARHGAP25	LTB4R2	ARHGAP24	MTNR1B	ARHGAP23	OR2L13	ARHGAP33	OR13C3	ARHGAP32	REST	OR13C2	ARHGAP31	OR13C5	ARHGAP30	OR13C4	ARHGAP11A	ARHGAP9	OR5AR1	ARHGAP11B	OR1Q1	ARHGAP8	OR4A47	ARHGAP1	OR5B21	ARHGAP5	REEP1	ARHGAP6	REEP5	ARHGAP4	REEP4	TAGAP	REEP3	RAC3	REEP2	REEP6	RHOG	OR13A1	ARAP2	OR13H1	RHOH	TRH	ARAP3	OR8D4	ARAP1	OR8D2	RHOF	GMIP	OR8D1	INSL5	RHOD	DEPDC7	OR6C70	OR6C76	RHOJ	OR6C75	RHOU	OR6C74	RHOV	OR13G1	CHN2	XCL2	CHN1	MYO9A	XCL1	CX3CR1	DLC1	OR6C65	OR8B8	OR8B4	OR6C68	OR13F1	OR8B3	OR8B2	OR5AU1	
PROCESSIVE SYNTHESIS ON THE C-STRAND OF THE TELOMERE%REACTOME DATABASE ID RELEASE 74%174414	Processive synthesis on the C-strand of the telomere	DNA2	TINF2	BLM	TERF1	TERF2	FEN1	PCNA	RPA1	POT1	RPA2	TERF2IP	ACD	LIG1	POLD3	POLD4	RPA3	POLD1	POLD2	WRN	
BIOSYNTHESIS OF EPA-DERIVED SPMS%REACTOME%R-HSA-9018679.1	Biosynthesis of EPA-derived SPMs	LTA4H	PTGS2	ALOX15	HPGD	ALOX5	
METHYLATION OF MESEH FOR EXCRETION%REACTOME%R-HSA-2408552.2	Methylation of MeSeH for excretion	INMT	
DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A%REACTOME DATABASE ID RELEASE 74%9662001	Defective factor VIII causes hemophilia A	F2	TPST2	TPST1	F8	F10	F9	VWF	
HYDROLYSIS OF LPE%REACTOME DATABASE ID RELEASE 74%1483152	Hydrolysis of LPE	PLA2G4C	GPCPD1	
CREATION OF C4 AND C2 ACTIVATORS%REACTOME%R-HSA-166786.2	Creation of C4 and C2 activators	FCN1	IGKV2-28	CRP	IGKV1-12	C1QB	IGKV3D-20	COLEC11	C1QA	IGKV2D-28	FCN2	COLEC10	IGKV4-1	FCN3	C1S	C1R	IGKV2D-30	IGHG4	IGKV3-11	IGKV5-2	IGHG1	IGHG2	MBL2	MASP1	C1QC	
DEFECTIVE F9 VARIANT DOES NOT ACTIVATE FX%REACTOME DATABASE ID RELEASE 74%9673202	Defective F9 variant does not activate FX	F8	F10	F9	
DEFECTIVE DPM3 CAUSES DPM3-CDG (CDG-1O)%REACTOME%R-HSA-4719360.1	Defective DPM3 causes DPM3-CDG (CDG-1o)	DPM1	DPM2	DPM3	
G PROTEIN GATED POTASSIUM CHANNELS%REACTOME%R-HSA-1296059.1	G protein gated Potassium channels	KCNJ5	KCNJ6	GABBR1	KCNJ10	KCNJ12	KCNJ9	KCNJ15	GNG12	KCNJ16	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	GNGT1	GNGT2	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	KCNJ2	KCNJ3	KCNJ4	GABBR2	
EPHRIN SIGNALING%REACTOME DATABASE ID RELEASE 74%3928664	Ephrin signaling	PAK3	PAK2	EPHB2	FYN	EPHB1	EPHB4	EFNB2	EPHB3	SDCBP	NCK2	EFNB1	RAC1	EFNB3	MYL12A	GIT1	PAK1	ARHGEF7	
DEFECTIVE ALG6 CAUSES ALG6-CDG (CDG-1C)%REACTOME%R-HSA-4724289.1	Defective ALG6 causes ALG6-CDG (CDG-1c)	ALG6	
METABOLISM OF INGESTED H2SEO4 AND H2SEO3 INTO H2SE%REACTOME%R-HSA-2408550.2	Metabolism of ingested H2SeO4 and H2SeO3 into H2Se	PAPSS1	TXNRD1	PAPSS2	
APC C-MEDIATED DEGRADATION OF CELL CYCLE PROTEINS%REACTOME%R-HSA-174143.1	APC C-mediated degradation of cell cycle proteins	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	SKP2	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	PSMB10	PSMA7	ANAPC4	CUL1	AURKB	PSMA8	AURKA	ANAPC5	PSMB6	PSMB7	CCNB1	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	FZR1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	PSMC2	UBE2S	PLK1	CDC16	CDK2	CDK1	RB1	PTTG1	CDC14A	FBXO5	BUB1B	CDC20	BUB3	MAD2L1	NEK2	BTRC	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
INTERLEUKIN-3, INTERLEUKIN-5 AND GM-CSF SIGNALING%REACTOME DATABASE ID RELEASE 74%512988	Interleukin-3, Interleukin-5 and GM-CSF signaling	IL2RG	CSF2RB	BLNK	JAK3	JAK1	PTPN11	CSF2RA	IL2RA	IL2RB	GAB2	SHC1	IL2	CBL	IL3	PTPN6	IL5	LYN	SOS1	PIK3R3	PIK3R2	HCK	PIK3R1	YWHAZ	SYK	PIK3CA	CRK	INPP5D	FYN	CSF2	STAT5A	STAT5B	PRKACA	PIK3CD	IL5RA	YES1	PIK3CB	VAV1	CRKL	RAPGEF1	JAK2	INPPL1	IL3RA	TEC	
PI-3K CASCADE:FGFR1%REACTOME DATABASE ID RELEASE 74%5654689	PI-3K cascade:FGFR1	PTPN11	FRS2	FGF20	FGF1	FGF23	FGF2	FGF22	FGF3	GAB1	FGF4	FGF6	FGF9	PIK3R1	PIK3CA	FGF10	
NF-KB ACTIVATION THROUGH FADD RIP-1 PATHWAY MEDIATED BY CASPASE-8 AND -10%REACTOME DATABASE ID RELEASE 74%933543	NF-kB activation through FADD RIP-1 pathway mediated by caspase-8 and -10	IFIH1	RNF135	MAVS	IKBKB	DDX58	CASP8	RIPK1	CASP10	TRIM25	FADD	IKBKG	CHUK	
MODULATION BY MTB OF HOST IMMUNE SYSTEM%REACTOME%R-HSA-9637628.1	Modulation by Mtb of host immune system	RPS27A	MRC1	TLR2	UBB	UBC	B2M	UBA52	
DEFECTIVE B3GALTL CAUSES PETERS-PLUS SYNDROME (PPS)%REACTOME DATABASE ID RELEASE 74%5083635	Defective B3GALTL causes Peters-plus syndrome (PpS)	ADAMTS16	ADAMTS18	SPON2	THBS1	SEMA5B	SPON1	THSD7B	ADAMTSL1	ADAMTS4	ADAMTS5	ADAMTSL4	ADAMTSL3	ADAMTSL2	ADAMTS1	THSD7A	ADAMTS6	ADAMTS2	ADAMTS7	ADAMTS3	SBSPON	ADAMTS20	B3GLCT	THBS2	CFP	ADAMTS8	ADAMTS12	THSD1	ADAMTS9	ADAMTS10	ADAMTS14	THSD4	ADAMTS15	ADAMTS13	ADAMTS19	ADAMTS17	SEMA5A	
BLOCKAGE OF PHAGOSOME ACIDIFICATION%REACTOME DATABASE ID RELEASE 74%9636467	Blockage of phagosome acidification	ATP6V1H	
ATTACHMENT AND ENTRY%REACTOME DATABASE ID RELEASE 74%9678110	Attachment and Entry	ACE2	CTSL	TMPRSS2	VCP	
REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION%REACTOME DATABASE ID RELEASE 74%6804756	Regulation of TP53 Activity through Phosphorylation	TAF11	TAF4B	TAF7	TAF6	TAF5	CHEK2	TAF4	CHEK1	PIN1	TAF3	TAF2	DYRK2	TAF1	MDM2	MDM4	UBA52	CCNA2	CCNA1	AURKB	CDK5	AURKA	PLK3	TP53INP1	UBB	UBC	BRCA1	NBN	RPS27A	TOP3A	TBP	SUPT16H	SSRP1	BLM	RBBP8	RPA1	RPA2	MRE11A	CDK2	MAPK14	MAPK11	CDK5R1	RAD50	RPA3	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	RAD17	RAD1	TP53RK	DNA2	RAD9B	CSNK2A1	RHNO1	NOC2L	ATR	RAD9A	CSNK2A2	PRKAA1	PRKAA2	KAT5	PRKAG1	PRKAG2	CSNK2B	NUAK1	PRKAG3	STK11	ATM	TPX2	PRKAB2	PRKAB1	RFC5	HIPK1	RFC3	HIPK2	RFC4	RFC2	TAF9	TAF1L	MAPKAPK5	AK6	TAF7L	TAF9B	TAF15	TAF12	TAF13	TP53	TAF10	
SYNTHESIS OF EPOXY (EET) AND DIHYDROXYEICOSATRIENOIC ACIDS (DHET)%REACTOME%R-HSA-2142670.1	Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	CYP2C9	CYP1B1	EPHX2	CYP2C19	CYP2C8	CYP1A2	CYP1A1	CYP2J2	
PHENYLALANINE AND TYROSINE METABOLISM%REACTOME DATABASE ID RELEASE 74%8963691	Phenylalanine and tyrosine metabolism	PAH	PCBD1	FAH	ASRGL1	CCBL1	HPD	GSTZ1	QDPR	IL4I1	HGD	TAT	
CELL JUNCTION ORGANIZATION%REACTOME%R-HSA-446728.2	Cell junction organization	LAMC2	ITGA6	JUP	CTNND1	F11R	CLDN2	CTNNB1	CLDN1	CDH9	PVR	CDH8	CDH7	ACTN1	CLDN22	FBLIM1	CDH6	FLNC	CDH5	LIMS2	CLDN20	FERMT2	CDH3	CLDN23	CLDN11	CLDN6	CLDN10	CLDN4	CLDN3	CLDN15	CLDN14	CLDN9	CLDN8	PARD3	CDH10	CLDN12	CLDN7	CDH11	CLDN19	CTNNA1	CDH12	ARHGEF6	CLDN18	PLEC	CDH13	CLDN17	ANG	CLDN16	CDH17	CDH18	PARD6G	TESK1	PARD6B	LAMA3	PARD6A	PARVB	CDH24	RSU1	CADM3	LIMS1	CADM1	CADM2	MPP5	INADL	LAMB3	SDK1	PVRL4	PVRL3	PVRL2	SDK2	PVRL1	FLNA	CRB3	ITGB1	DST	CDH15	PXN	ILK	CDH1	CDH4	CLDN5	CDH2	VASP	PRKCI	CD151	COL17A1	ITGB4	
EPHB-MEDIATED FORWARD SIGNALING%REACTOME%R-HSA-3928662.2	EPHB-mediated forward signaling	ROCK1	ARPC4	ROCK2	LIMK2	ARPC5	LIMK1	RHOA	ARPC2	ARPC3	LYN	HRAS	SDC2	TIAM1	KALRN	ARHGEF28	GRIN1	FYN	RAC1	YES1	ARPC1B	ARPC1A	WASL	ACTB	ACTG1	CFL1	ITSN1	ACTR3	RASA1	CDC42	ACTR2	GRIN2B	PTK2	PAK1	
METABOLISM OF SEROTONIN%REACTOME%R-HSA-380612.3	Metabolism of serotonin	MAOA	ALDH2	
CLASS C 3 (METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS)%REACTOME DATABASE ID RELEASE 74%420499	Class C 3 (Metabotropic glutamate pheromone receptors)	TAS2R40	CASR	TAS2R41	TAS2R42	GABBR1	TAS2R43	TAS1R2	TAS2R46	TAS1R1	TAS1R3	TAS2R30	TAS2R31	TAS2R38	TAS2R39	GPRC6A	TAS2R60	TAS2R7	TAS2R9	TAS2R8	GRM1	TAS2R50	GRM3	GRM2	GRM5	GRM4	GRM7	GRM6	GRM8	TAS2R1	TAS2R20	TAS2R3	TAS2R5	TAS2R4	TAS2R10	TAS2R13	TAS2R14	TAS2R16	TAS2R19	GABBR2	
MATURATION OF PROTEIN E%REACTOME DATABASE ID RELEASE 74%9683683	Maturation of protein E	RPS27A	UBB	UBC	UBA52	
SIGNALING BY MAPK MUTANTS%REACTOME%R-HSA-9652817.1	Signaling by MAPK mutants	DUSP9	DUSP6	DUSP7	DUSP16	MAPK1	DUSP10	DUSP8	
TRANSLOCATION OF SLC2A4 (GLUT4) TO THE PLASMA MEMBRANE%REACTOME%R-HSA-1445148.2	Translocation of SLC2A4 (GLUT4) to the plasma membrane	RALA	TBC1D4	YWHAB	RAB10	RAB14	KIF3B	YWHAZ	RAB13	LNPEP	STXBP3	RAC1	C2CD5	VAMP2	STX4	MYO5A	PRKAA2	MYO1C	RHOQ	PRKAG1	RALGAPA2	PRKAG2	PRKAG3	RALGAPB	MYH9	PRKAB2	SLC2A4	PRKAB1	AKT2	RAB4A	YWHAE	YWHAQ	AKT1	EXOC8	SFN	EXOC7	YWHAH	RAB11A	KIF3A	EXOC4	EXOC3	EXOC6	YWHAG	RAB8A	EXOC5	EXOC2	ASPSCR1	EXOC1	KIFAP3	SNAP23	TBC1D1	
INTERLEUKIN-10 SIGNALING%REACTOME%R-HSA-6783783.3	Interleukin-10 signaling	CSF1	CXCL1	CXCL2	CXCL8	IL1R2	FCER2	PTAFR	PTGS2	ICAM1	CCL2	JAK1	IL1R1	TYK2	CXCL10	CCL5	CCL4	TNFRSF1B	CCL3	CD86	IL12B	CD80	IL12A	CCR1	LIF	TIMP1	IL10	IL6	CCR2	TNFRSF1A	CSF2	FPR1	CCR5	STAT3	TNF	IL18	IL1A	CCL19	IL1B	CCL22	CCL20	IL10RB	CCL3L1	IL10RA	CCL3L3	IL1RN	CSF3	
DEFECTIVE CD320 CAUSES METHYLMALONIC ACIDURIA%REACTOME%R-HSA-3359485.1	Defective CD320 causes methylmalonic aciduria	TCN2	CD320	
PROTEIN FOLDING%REACTOME DATABASE ID RELEASE 74%391251	Protein folding	TUBA4A	GNG12	GNG11	GNG13	DCAF7	GNAO1	CCT6B	KIF13A	FBXO4	FBXO6	RGS9	GNB2	GNAT1	RGS6	RGS7	CCNE2	GNB1	FBXW4	CCNE1	FBXW5	GNB4	FBXW10	GNB3	FBXW7	GNB5	VBP1	SPHK1	FBXW9	TUBA4B	NOP56	FBXW2	PFDN1	FBXL5	PFDN2	FKBP9	CCT3	PFDN4	PFDN5	CCT2	PFDN6	TUBAL3	USP11	GBA	AP3M1	CCT7	ARFGEF2	CCT6A	PDCL	FBXL3	SKIV2L	TCP1	RGS11	TUBA8	TUBB4B	WRAP53	CCT8	TUBB4A	CCT5	CCT4	GAPDHS	ARL2	TUBA3E	TUBA1C	TUBB6	TUBA1B	TUBB3	TUBB1	TUBB2B	TUBB2A	STAT3	TBCD	TBCC	TBCB	TBCA	TBCE	GNAT3	ACTB	HDAC3	GNAI3	GNAI1	GNAI2	LONP2	CSNK2A1	CSNK2A2	XRN2	CSNK2B	GNAZ	GNGT1	GNGT2	GNAT2	TUBA1A	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	TP53	
DEFECTIVE SLC34A1 CAUSES HYPOPHOSPHATEMIC NEPHROLITHIASIS OSTEOPOROSIS 1 (NPHLOP1)%REACTOME%R-HSA-5619040.1	Defective SLC34A1 causes hypophosphatemic nephrolithiasis osteoporosis 1 (NPHLOP1)	SLC34A1	
CALNEXIN CALRETICULIN CYCLE%REACTOME%R-HSA-901042.2	Calnexin calreticulin cycle	PRKCSH	GANAB	UBA52	EDEM2	SEL1L	MAN1B1	UBB	EDEM1	UBC	SYVN1	RNF139	RPS27A	UGGT2	UGGT1	RNF185	PDIA3	EDEM3	AMFR	MARCH6	RNF103	TRIM13	CALR	CANX	DERL2	RNF5	OS9	
HSF1-DEPENDENT TRANSACTIVATION%REACTOME DATABASE ID RELEASE 74%3371571	HSF1-dependent transactivation	FKBP4	CRYAB	AKT1S1	CAMK2G	DNAJB1	HSP90AB1	HSPA8	CAMK2A	HSF1	HSPA1L	RPTOR	PTGES3	HSP90AA1	HSPA2	CREBBP	HSPB8	MTOR	EP300	HSBP1	CAMK2B	CAMK2D	MLST8	
INTERLEUKIN-12 SIGNALING%REACTOME DATABASE ID RELEASE 74%9020591	Interleukin-12 signaling	RALA	SNRPA1	CA1	PAK2	CAPZA1	LMNB1	MTAP	JAK1	GSTO1	BOLA2B	HNRNPDL	PSME2	PPIA	RAP1B	TYK2	HNRNPA2B1	LCP1	RPLP0	TALDO1	IFNG	PITPNA	STAT4	SOD2	PDCD4	P4HB	IL12B	IL12A	AIP	BOLA2	IL10	TCP1	ARF1	GSTA2	SERPINB2	ANXA2	MSN	HNRNPF	MIF	CFL1	JAK2	IL12RB1	IL12RB2	CDC42	VAMP7	HSPA9	CNN2	SOD1	
TWIK-RELATED SPINAL CORD K+ CHANNEL (TRESK)%REACTOME%R-HSA-1299344.1	TWIK-related spinal cord K+ channel (TRESK)	KCNK18	
TRANSCRIPTION-COUPLED NUCLEOTIDE EXCISION REPAIR (TC-NER)%REACTOME%R-HSA-6781827.1	Transcription-Coupled Nucleotide Excision Repair (TC-NER)	POLK	XRCC1	LIG3	UBA52	COPS7B	COPS7A	ELL	UBB	UBC	RPS27A	HMGN1	AQR	ZNF830	UVSSA	ERCC8	TCEA1	RPA1	RPA2	RPA3	PRPF19	ERCC4	GPS1	ERCC1	XAB2	CCNH	XPA	CUL4A	DDB1	POLR2A	POLR2B	ERCC5	POLR2C	CUL4B	PPIE	POLR2D	POLR2E	RBX1	POLR2F	POLR2G	POLR2H	RFC5	POLR2I	RFC3	POLR2J	PCNA	POLR2K	RFC4	POLR2L	GTF2H1	RFC1	GTF2H2	COPS4	LIG1	GTF2H3	COPS3	RFC2	GTF2H4	COPS6	ISY1	POLE4	POLD3	GTF2H5	COPS5	USP7	POLD4	CDK7	COPS2	POLE2	POLD1	ERCC3	POLE3	POLD2	COPS8	POLE	ERCC2	ERCC6	EP300	MNAT1	
G ALPHA (Z) SIGNALLING EVENTS%REACTOME%R-HSA-418597.4	G alpha (z) signalling events	ADCY2	RGS19	ADCY1	PRKCH	ADCY8	PRKCB	PRKCE	ADCY7	ADCY6	ADCY5	PRKCA	GNG12	GNG11	RGS16	GNG13	GNB2	PRKCQ	GNAZ	PRKCG	GNB1	GNB4	RGS20	GNB3	GNB5	PRKCD	GNAT3	GNGT1	GNGT2	ADCY9	RGSL1	GNAS	GNG3	GNG10	ADRA2C	GNG2	GNG5	ADRA2A	GNG4	RGS4	GNG7	GNG8	GNAI3	ADCY4	GNAI1	RGS17	ADCY3	GNAI2	
DEFECTIVE SLC35A1 CAUSES CONGENITAL DISORDER OF GLYCOSYLATION 2F (CDG2F)%REACTOME DATABASE ID RELEASE 74%5619037	Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F)	SLC35A1	
OTHER SEMAPHORIN INTERACTIONS%REACTOME%R-HSA-416700.1	Other semaphorin interactions	SEMA7A	PTPRC	SEMA4D	PLXNA2	SEMA4A	CD72	PLXNA1	SEMA5A	PLXNA4	PLXND1	ITGA1	ITGB1	PLXNB3	PLXNC1	TREM2	TYROBP	SEMA6A	SEMA6D	SEMA3E	
DEFECTIVE ALG1 CAUSES ALG1-CDG (CDG-1K)%REACTOME%R-HSA-4549380.1	Defective ALG1 causes ALG1-CDG (CDG-1k)	ALG1	
DEFECTS IN VITAMIN AND COFACTOR METABOLISM%REACTOME DATABASE ID RELEASE 74%3296482	Defects in vitamin and cofactor metabolism	MTRR	ACACA	MMAB	GIF	MTR	CUBN	PCCA	LMBRD1	PCCB	AMN	PC	MCCC2	MMACHC	MMADHC	MCCC1	BTD	HLCS	ABCD4	MMAA	TCN2	MUT	CD320	
CELL DIVISION%REACTOME%R-HSA-68884.3	cell division	KIF23	STAG1	STAG2	KIF20A	WAPAL	PLK1	SMC1A	NIPBL	MAU2	SMC3	PDS5B	PDS5A	RAD21	
DEFECTIVE MISMATCH REPAIR ASSOCIATED WITH MSH6%REACTOME DATABASE ID RELEASE 74%5632968	Defective Mismatch Repair Associated With MSH6	MSH6	MSH2	
ANTIGEN ACTIVATES B CELL RECEPTOR (BCR) LEADING TO GENERATION OF SECOND MESSENGERS%REACTOME%R-HSA-983695.4	Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	SH3KBP1	BLNK	IGKV2-28	PIK3AP1	DAPP1	CD19	IGKV1-12	IGKV3D-20	CD22	IGKV2D-28	IGKV4-1	IGKV2D-30	PTPN6	IGKV3-11	LYN	IGKV5-2	SOS1	CD79B	CD79A	PIK3R1	SYK	STIM1	ORAI2	ORAI1	FYN	AHCYL1	TRPC1	PIK3CD	ITPR1	ITPR2	ITPR3	VAV1	BLK	PLCG2	NCK1	BTK	
PKA ACTIVATION%REACTOME%R-HSA-163615.3	PKA activation	ADCY2	NBEA	ADCY1	ADCY8	ADCY7	ADCY6	ADCY9	ADCY5	PRKAR1B	PRKAR1A	PRKAR2A	PRKACA	PRKAR2B	ADCY4	PRKACG	ADCY3	PRKACB	
RNA POLYMERASE II TRANSCRIPTION ELONGATION%REACTOME%R-HSA-75955.2	RNA Polymerase II Transcription Elongation	CTDP1	ELL	CCNT1	SUPT4H1	TCEB3	TCEB2	TCEB1	NELFA	NELFCD	TCEB3C	TCEB3CL	TCEB3B	NELFE	GTF2F1	SUPT16H	GTF2F2	SSRP1	SUPT5H	CDK9	TCEA1	TCEB3CL2	CCNK	NELFB	CDC73	CCNH	CTR9	WDR61	RTF1	POLR2A	POLR2B	POLR2C	NCBP1	POLR2D	LEO1	NCBP2	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	PAF1	POLR2K	POLR2L	GTF2H1	GTF2H2	CCNT2	AFF4	GTF2H3	MLLT1	GTF2H4	MLLT3	SUPT6H	GTF2H5	IWS1	EAF1	EAF2	CDK7	ERCC3	ERCC2	MNAT1	
MEIOSIS%REACTOME%R-HSA-1500620.2	Meiosis	STAG1	LMNB1	STAG2	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	SMC1A	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	PRDM9	HIST1H2BJ	SPO11	HIST1H2BI	BRCA1	HIST1H2BL	BRCA2	NBN	TOP3A	HIST1H2BK	TEX15	MSH4	HIST2H4A	DMC1	MSH5	HIST2H4B	BLM	PSMC3IP	RBBP8	RPA1	RPA2	CDK2	MRE11A	HIST3H3	MND1	MLH1	MLH3	RAD50	RAD51C	RAD51	RPA3	ATR	ATM	FKBP6	UBE2I	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	SYCP2	SYCP1	TINF2	SYNE2	SYNE1	TERF1	SUN2	TERF2	SUN1	TEX12	POT1	HIST2H3A	SMC1B	TERF2IP	HIST1H2BF	SYCE3	ACD	HIST1H2BE	SYCE2	HIST1H2BH	SYCE1	HIST1H2BG	REC8	HIST2H3D	STAG3	HIST1H2BB	SYCP3	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	HSPA2	H2AFB1	HIST1H3J	HIST1H3A	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	CDK4	HIST1H4L	H3F3A	SMC3	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	RAD21	HIST2H2AA4	
INTRA-GOLGI TRAFFIC%REACTOME DATABASE ID RELEASE 74%6811438	Intra-Golgi traffic	RAB30	RAB36	BET1L	TRIP11	RAB33B	VPS45	MAN2A2	MAN2A1	VTI1A	NAPA	NAPB	RAB39A	STX16	GOSR2	ALPP	GOSR1	NAPG	GOLIM4	CYTH3	ARF1	CYTH2	CYTH4	RAB41	CUX1	GOLGA5	MAN1C1	MAN1A2	STX6	STX5	YKT6	CYTH1	NSF	MAN1A1	COG8	RIC1	COG7	COG6	COG5	SNAP29	COG4	COG3	COG2	RGP1	COG1	
INHIBITION OF TSC COMPLEX FORMATION BY PKB%REACTOME DATABASE ID RELEASE 74%165181	Inhibition of TSC complex formation by PKB	TSC2	TSC1	AKT2	
TRKA ACTIVATION BY NGF%REACTOME%R-HSA-187042.1	TRKA activation by NGF	NGF	NTRK1	
MET RECEPTOR ACTIVATION%REACTOME DATABASE ID RELEASE 74%6806942	MET Receptor Activation	SPINT2	HGFAC	SPINT1	HPN	HGF	MET	
RECYCLING OF BILE ACIDS AND SALTS%REACTOME DATABASE ID RELEASE 74%159418	Recycling of bile acids and salts	ABCB11	RXRA	SLCO1B1	SLCO1B3	ABCC3	FABP6	ALB	SLC10A1	BAAT	SLCO1A2	SLC10A2	NCOA1	NCOA2	NR1H4	SLC27A5	STARD5	
TRANSLATION OF STRUCTURAL PROTEINS%REACTOME%R-HSA-9694635.1	Translation of structural proteins	RPN2	PRKCSH	TUSC3	RPN1	MAGT1	GANAB	FUT8	MGAT5	ST3GAL4	MGAT1	MGAT2	ST3GAL1	ST3GAL2	UBA52	ST3GAL3	ST6GAL1	EDEM2	MOGS	DDOST	MGAT4C	DAD1	MGAT4A	MGAT4B	PARP16	STT3A	PARP14	MAN1B1	UBB	PARP10	ST6GALNAC3	MAN2A1	PARP6	ST6GALNAC4	PARP4	PARP9	UBC	PARP8	RPS27A	GSK3B	CANX	SUMO1	UBE2I	GALNT1	ST6GALNAC2	
PEPTIDE LIGAND-BINDING RECEPTORS%REACTOME%R-HSA-375276.5	Peptide ligand-binding receptors	EDNRA	EDNRB	UTS2R	GPR37L1	UTS2B	CXCR4	SSTR3	SAA1	MCHR1	NLN	PPY	PDYN	NTSR1	CCR10	NTSR2	NMB	XCR1	NMBR	NMS	NMU	CX3CL1	BRS3	CCKAR	GRP	CXCL8	CCL2	EDN1	EDN2	EDN3	CCKBR	NPB	CXCR5	CXCR6	CXCR1	NPW	CXCR3	CXCR2	KISS1R	CXCL12	F2RL1	PMCH	NPY2R	GHSR	NPY1R	APLNR	AGTR2	NTS	NPBWR1	NPBWR2	PYY	NMUR2	NMUR1	GPR37	CXCL6	CXCL9	NPFFR2	MLNR	SST	NPFFR1	NPFF	QRFPR	HCRT	PSAP	CXCL3	QRFP	CXCL5	HCRTR2	CCR5	PROKR1	HCRTR1	PROKR2	BDKRB2	BDKRB1	PPBP	NPY5R	CXCL13	CXCL16	CORT	C5AR2	C5AR1	C5	NPY4R	UTS2	OPRL1	CXCL11	ECE1	F2RL2	F2RL3	PRLHR	AVP	KISS1	CCL7	CCL1	APLN	KEL	OXTR	AVPR1B	OXT	AVPR1A	PENK	MLN	CCR9	CCR8	CCR7	CCR6	CCR4	CCR3	GAL	PRLH	XK	CCRL2	MCHR2	TAC3	TAC1	HEBP1	ANXA1	FPR1	FPR3	FPR2	GPER1	CCL11	SSTR1	SSTR2	SSTR4	CCL19	SSTR5	CCL22	AGT	CCL20	CXCL10	CCK	CCL5	CCL4	AGTR1	CCL3	ACKR4	ACKR3	ACKR2	ACKR1	RXFP4	RXFP1	RXFP2	GRPR	RXFP3	CCR1	C3AR1	PROK2	PROK1	MC2R	CCR2	TRHR	MC1R	GALR3	GALR2	GALR1	MC4R	NPY	OPRD1	PNOC	MC3R	TACR2	TACR1	TACR3	NPSR1	CCL3L1	CCL13	CCL3L3	NPS	CXCL1	CCL17	CXCL2	CCL16	CCL25	CCL21	MC5R	OPRM1	CCL28	CCL27	C3	OPRK1	RLN2	RLN3	APP	INSL3	AVPR2	KNG1	POMC	TRH	F2R	INSL5	F2	XCL2	XCL1	CX3CR1	PF4	
PHOSPHO-PLA2 PATHWAY%REACTOME DATABASE ID RELEASE 74%111995	phospho-PLA2 pathway	PLA2G4A	MAPK1	
SIGNAL AMPLIFICATION%REACTOME DATABASE ID RELEASE 74%392518	Signal amplification	AAMP	PLA2G4A	GNG12	GNG11	P2RY12	GNG13	GNA14	GNB2	GNA15	GNA11	GNB1	GNAQ	GNB4	GNB3	GNB5	GNAT3	P2RY1	GNGT1	GNGT2	MAPK14	GNG3	GNA13	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	GNAI3	TBXA2R	GNAI1	GNAI2	
PRE-NOTCH PROCESSING IN GOLGI%REACTOME DATABASE ID RELEASE 74%1912420	Pre-NOTCH Processing in Golgi	ATP2A1	NOTCH3	NOTCH4	ST3GAL4	ST3GAL3	NOTCH2	NOTCH1	SEL1L	LFNG	ST3GAL6	RFNG	TMED2	B4GALT1	MFNG	FURIN	RAB6A	ATP2A3	ATP2A2	
ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS%REACTOME DATABASE ID RELEASE 74%176187	Activation of ATR in response to replication stress	RAD17	RAD1	RAD9B	ATR	MCM7	RAD9A	MCM8	CHEK1	CDC25A	CDC7	CDC25C	MCM3	MCM4	MCM10	MCM5	DBF4	MCM6	CLSPN	MCM2	ORC5	ORC4	ORC6	ORC1	ORC3	ORC2	RFC5	RFC3	CDC6	RPA1	RFC4	RPA2	CDK2	RFC2	RPA3	CDC45	ATRIP	HUS1	
SCF(SKP2)-MEDIATED DEGRADATION OF P27 P21%REACTOME%R-HSA-187577.3	SCF(Skp2)-mediated degradation of p27 p21	PSMA6	PSMA3	CDKN1A	PSMA4	CDKN1B	PSMA1	PSMA2	PSME3	PSME1	PSME2	PSMD10	SKP2	UBA52	PSMD12	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	CCNE2	CCNE1	PSMB10	PSMA7	CUL1	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CDK2	PTK6	CKS1B	CCND1	CDK4	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
GPCR DOWNSTREAM SIGNALLING%REACTOME%R-HSA-388396.6	GPCR downstream signalling	OR11A1	OR8A1	OR8I2	OR52N1	RRH	OR52N5	OR52N4	OR52N2	EDNRA	OR5D18	EDNRB	OR10W1	OR2A42	OR5D16	OR5D14	OR5D13	OR8H3	OR8H2	UTS2R	OR8H1	GPR37L1	OR52M1	UTS2B	OR10V1	ABCA4	OR4C12	OR6C6	OR4C11	OR6C4	OR6C3	OR4C16	CXCR4	OR8G5	OR6C2	OR4C15	OR5AK2	OR6C1	OR4C13	OR8G1	OR10T2	OR52L1	PPY	OR6B3	OR6B2	OR6B1	PDYN	NTSR1	APOA1	SLC24A1	CCR10	NTSR2	PIK3CG	OR2A25	NMB	VAV1	XCR1	PIK3R5	PDE2A	OR10S1	NMBR	OR52K2	OR52K1	NMS	NMU	PDE3A	OR2A12	OR6A2	OR2A14	OR2A1	OR4E2	CX3CL1	BRS3	CCKAR	FFAR3	OR4D9	FFAR2	OR5AP2	OR5B12	OR4D6	OR4D5	OR5B17	OR4D2	OR4D1	EDN1	EDN2	EDN3	OR10Z1	CCKBR	OR52R1	OR4C6	OR4C5	OR4A15	OR4C3	OR4A16	OR8K5	NPB	OR8K3	OR8K1	CXCR5	CXCR6	CXCR1	NPW	CXCR3	CXCR2	KISS1R	OR5AN1	OR4B1	OR4C46	OR6F1	OR8J3	OR8J1	OR10X1	F2RL1	OR4A5	CCL4L2	PMCH	NPY2R	OR6M1	OR2T12	OR2T10	OR2T11	OR5H15	OR5H14	PDE8B	PDE8A	GHSR	OR2D3	OR2D2	OR52E4	OR52E2	NPY1R	OR5AC2	APLNR	OR52E8	OR52E6	OR52E5	OR2C3	OR6K6	OR2C1	SUCNR1	OR6K3	OR6K2	OR52D1	NTS	OR2B6	OR4F6	OR2B3	OR4F5	OR2B2	OR10K2	OR4F4	OR4F3	OR10K1	OPN4	OPN3	OR6J1	OPN5	PYY	NMUR2	PRKCD	NMUR1	OR2A7	OR2A5	OR2A4	OR2A2	TAS2R7	GPSM1	CXCL6	GPSM2	TAS2R9	CXCL9	OR52J3	TAS2R8	MLNR	OR4M2	OR4M1	OR10R2	PSAP	CXCL3	OR6Q1	CXCL5	CCR5	OR8U1	BDKRB2	BDKRB1	TAS2R1	PPBP	TAS2R3	TAS2R5	GPSM3	TAS2R4	OR52I2	OR52I1	NPY5R	OR2H2	VAV3	OR2H1	OR4L1	VAV2	OR6P1	OR10Q1	CORT	BTK	RGS18	OR2G6	RGS17	OR52H1	RGS19	OR2G3	OR4K5	RGS14	NPY4R	OR2G2	RGS13	P2RY12	RGS16	OR4K2	OPRL1	OR4K1	OR10P1	OR2T34	OR8S1	OR2T35	OR2T33	PDE11A	RGS21	RGS20	S1PR3	S1PR2	RGS22	S1PR5	S1PR4	OR2T27	OR2F2	OR2F1	OR2T29	OR6N2	PRKACG	OR6N1	PRKACB	KISS1	PDE10A	RGS10	RGS12	PDE7B	ADCY9	PDE7A	PRKAR1B	PRKAR1A	PRKAR2A	GNAS	ADCY4	ADCY3	ADCY2	OXTR	ADCY1	AVPR1B	OXT	ADCY8	ADCY7	AVPR1A	ADCY6	ADCY5	HBEGF	FNTA	FNTB	PIK3R6	GABBR2	GABBR1	PPP1CA	RASGRF2	PDE3B	ARRB1	ARRB2	HEBP1	ANXA1	FPR1	FPR3	FPR2	PPP2R5D	AKR1C3	CCL19	CCL20	CAMK2B	CAMK2D	CAMK2G	CXCL10	CCL5	CCL4	OPN1SW	OPN1MW	OPN1LW	RBP3	OPN1MW2	CCR1	DHRS3	RLBP1	CCR2	OPRD1	CXCL1	CXCL2	C3	GPR17	P2RY13	P2RY10	P2RY14	LPAR4	P2RY6	APP	P2RY4	LPAR6	P2RY2	ADORA3	P2RY1	ADORA1	PREX1	ARHGEF40	TIAM2	OBSCN	ARHGEF26	ABR	ECT2	ARHGEF33	ARHGEF35	ARHGEF37	ARHGEF39	RGS9	ARHGEF38	RGS6	RGS7	NET1	ARHGEF10L	AKAP13	MCF2L	ARHGEF10	PLEKHG2	ARHGEF15	MAPK7	PLEKHG5	ARHGEF17	ARHGEF16	ARHGEF19	SSTR3	MCHR1	ARHGEF18	SAA1	ARHGEF9	ARHGEF3	RGS11	ARHGEF4	ARHGEF1	ARHGEF2	ARHGEF5	ARHGEF6	FGD1	FGD2	GNA13	FGD3	FGD4	MCF2	GRP	FFAR4	FFAR1	SST	NPFFR2	NPFFR1	NPFF	QRFPR	HCRT	QRFP	HCRTR2	HCRTR1	GNA14	GNA15	GNA11	GNA12	GNAQ	F2RL2	F2RL3	ADORA2A	GNGT1	PPP3CA	PPP3CB	GNGT2	GNAT2	PLCB3	PLCB1	PLCB2	CAMK2A	ITPR1	ITPR2	ITPR3	GNG3	GNG10	PPP3R1	GNG2	GNG5	GNG4	GNG7	GNG8	PDE6B	PDE6A	PDE6G	GNG12	GNG11	GNG13	GNAO1	GNB2	GNB1	GNB4	GNB3	CDK5	GNB5	CDC42	ARHGEF11	ARHGEF12	ROCK1	ROCK2	RHOC	RHOA	RHOB	PLXNB1	PPP3CC	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	AGTR1	EGFR	NRAS	SOS1	HRAS	RXFP1	RXFP2	GPR176	GNAT3	C3AR1	PTGDR	LHB	CRHR2	MC2R	CGA	GPR15	MC1R	GPR27	APOA2	GPR25	GPR20	APOA4	MC4R	GPR39	NPY	FSHB	GPR32	GPBAR1	MC3R	FSHR	TACR1	NPSR1	PTGER4	GPR45	PTGER2	LPL	GNAI3	GNAI1	GNAI2	NPS	APOE	APOB	GPR150	LDLR	GPHA2	P2RY11	ADRBK2	GPIHBP1	MC5R	GPHB5	OPRM1	CYSLTR1	LHCGR	APOC3	GNAZ	APOC2	GPR83	GPR84	OPRK1	RLN2	RLN3	INSL3	TSHB	PTGIR	AVPR2	ADORA2B	TSHR	POMC	PPP2R1A	PRKACA	CLPS	PNLIP	LRP1	LRP2	PRKAR2B	CXCL8	NMT1	NMT2	PLB1	C5AR1	C5	SRC	AVP	CREB1	PLA2G4A	MGLL	AWAT2	CAMKK1	CAMKK2	NBEA	CAMK4	SDC4	SDC3	GPC3	SDC1	GPC2	GPC5	GPC4	GPC6	PTGFR	TBXA2R	PTGDR2	GUCA1B	GUCA1A	PTGER1	GUCA1C	PTGER3	CNGA1	CAMKMT	RBP2	RGS9BP	SAG	PPEF1	GUCY2D	RETSAT	GUCY2F	LRP8	GRK1	APOM	GRK7	BCO2	BCO1	RCVRN	AKR1C1	AKR1C4	AKR1B10	LRP10	METAP1	LRP12	METAP2	AGT	GNAL	KPNA2	AHCYL1	PRKX	PPP2R1B	PRKCB	PRKCA	ITSN1	NGEF	PPP2CA	PPP2CB	MAPK1	AGRN	GLP1R	VIPR1	VIPR2	SCT	ADM	PTH1R	CYSLTR2	GLP2R	PTH2R	CXCL12	GIP	ADCYAP1	CRH	IAPP	CALCA	RAMP2	RHO	ADCYAP1R1	RAMP3	CALCRL	CALCB	GIPR	PTH	PTH2	CNGB1	PTHLH	CRHR1	OR2M7	GHRHR	OR2M5	OR2M4	CALCR	OR2M3	OR4K17	OR2M2	OR4Q3	OR2L8	OR2L5	OR2L3	OR4P4	OR2L2	OR10AD1	OR6T1	OR4K15	OR4K14	SCTR	OR4K13	AGTR2	OR2K2	GCG	OR6S1	ADM2	NPBWR1	GHRH	NPBWR2	VIP	OR10D3	RAMP1	OR8B12	PRKCQ	OR14K1	OR4N5	OR2J3	RASGRP2	OR4N4	RASGRP1	OR2J2	OR2J1	OR4N2	OR10C1	GPR18	OR10J1	OR10J3	OR10J5	GPRC6A	OR6Y1	OR52B2	OR52B6	GPR37	SDC2	GPR31	OR6X1	KALRN	OR52A1	OR52A5	OR10H1	OR10H3	OR10H2	OR10H5	OR10H4	OR4S2	OR4S1	PROKR1	PROKR2	OR10G2	OR14A16	OR10G4	GPR55	OR10G3	OR6V1	OR10G6	OR10G8	OR10G7	OR10G9	GPR68	GPR65	CXCL13	CXCL16	OR14C36	OR2T8	OR2T7	OR2T6	ARHGEF7	OR2T5	OR2T4	OR2T3	OR2T2	OR2T1	GPC1	OR4X2	OR4X1	OR9A4	OR51T1	OR9A2	UTS2	OR2S2	OR51S1	CXCL11	OR7E24	OR7A10	OR14J1	OR2Y1	OR56B1	PDPK1	OR56B4	OR7A17	OR14I1	PIK3R3	OR10A7	PIK3R2	OR56A5	PIK3R1	OR7A5	PIK3CA	OR10A2	OR56A4	AKT2	OR10A4	AKT3	OR10A3	OR56A3	OR10A6	OR10A5	AKT1	OR56A1	OR2W3	OR2W1	CCL1	OR12D3	OR12D2	APLN	OR51V1	OR2V2	OR2V1	OR7G2	OR7G1	OR9K2	TAS2R20	RGSL1	OR51L1	OXER1	OR5B3	OR5B2	TAS2R10	TAS2R13	TAS2R14	TAS2R16	TAS2R19	OR2AT4	OR5A2	PAK1	OR5A1	OR9I1	TAS2R40	TAS2R41	TAS2R42	TAS2R43	LPAR1	TAS2R46	LPAR2	LPAR3	OR51J1	PENK	OR7D4	OR7D2	TAS2R30	OR51I2	TAS2R31	TAS2R38	GNAT1	TAS2R39	PRKCG	OR51I1	PLCB4	LPAR5	PDE1C	GNRH2	PDE1B	OR4D11	PDE1A	GNRH1	ADRBK1	OR4D10	OR2Z1	OR9G4	OR7C2	OR7C1	OR9G1	TAS2R60	MLN	OR51Q1	GNRHR	TRIO	CCR9	CCR8	CCR7	CCR6	CCR4	CCR3	OXGR1	TAS2R50	OR5F1	GAL	OR3A3	OR14A2	OR3A2	OR3A1	OR51M1	OR5C1	OR7G3	OR1C1	OR5K4	OR5K3	SDR9C7	MYO7A	OR5K2	HSD17B6	OR51D1	RPE65	OR5K1	RBP4	RGS4	RGS5	TTR	RDH12	RGS2	RGS3	DHRS9	RDH11	RGS1	CYP4V2	RDH10	RGS8	HSD17B1	CASR	RBP1	OR1B1	NAPEPLD	OR5J2	RDH16	PCP2	PTAFR	OR1A2	RDH5	LRAT	OR1A1	OR51B2	STRA6	ARHGEF25	OR5I1	OR9Q2	OR9Q1	MCHR2	HCAR2	HCAR3	OR2AK2	HCAR1	GRK5	GRK6	OR51B6	OR51B5	TAC3	OR51B4	TAC1	OR5H6	OR5H2	OR5H1	OR2AJ1	OR51A4	OR51A2	OR51A7	RTP4	RTP5	RTP2	OR51H1	RTP3	RTP1	OR1G1	OR10AG1	GRM1	LTB4R	GRM3	GRM2	GRM5	GRM4	GRM7	GRM6	GPER1	GRM8	OR51G2	OR51G1	OR1F1	SSTR1	HSPG2	SSTR2	SSTR4	SSTR5	OR2AP1	OR2B11	OR51F2	DGKG	OR51F1	DGKE	OR5M9	DGKD	OR5M8	DAGLA	OR1E2	DGKB	OR1E1	DGKA	OR5M3	ABHD6	OR5M1	ABHD12	CNR2	PRKCH	CNR1	PRKCE	OR4F29	DGKZ	TAS1R2	DGKQ	TAS1R1	DAGLB	TAS1R3	DGKK	OR4F21	DGKI	OR51E1	DGKH	OR1D5	OR1D2	OR51E2	OR5L2	OR5L1	CCK	OR4F17	OR4F16	OR4F15	CHRM2	CHRM3	ACKR3	CHRM1	CHRM4	CHRM5	HTR2B	OR11H2	HTR2C	OR11H1	OR11H4	ADRA1D	RXFP4	ADRB1	HTR2A	OR1K1	GRPR	ADRB2	RXFP3	ADRA1B	HTR4	OR2AE1	OR11H6	ADRA1A	PROK2	HRH1	HTR6	PROK1	HTR7	TRPC7	OR1J4	OR11G2	HRH2	OR1J2	TRPC6	HRH4	OR1J1	DRD1	OR5R1	TRPC3	TRHR	DRD3	MMP3	OR13J1	DRD4	OR1I1	DRD5	TAAR8	OR5M11	HTR1E	OR5M10	TAAR9	GALR3	HTR1F	GALR2	TAAR6	GALR1	HTR1D	OR5P3	OR5P2	HTR1B	GPR183	TAAR5	PNOC	TAAR2	OR11L1	GPR132	ADRA2C	HTR5A	OR5W2	TAAR1	GAST	TACR2	ADRA2A	TACR3	GPR143	SOS2	OR1N2	ADRB3	OR1N1	OR5V1	RGR	CCL13	OR1M1	OR2AG1	OR2AG2	CCL16	CCL25	CCL21	OR1L8	OR1L6	OR1L4	GPR4	OR1L3	OR1L1	OR5T3	OR5T2	OR5T1	CCL28	CCL27	OR52W1	OR1S2	OR1S1	OR13D1	OR5AS1	MTNR1A	OR13C9	OR13C8	LTB4R2	MTNR1B	OR2L13	OR13C3	OR13C2	OR13C5	OR13C4	OR5AR1	KNG1	OR1Q1	TIAM1	PDE4B	OR4A47	PDE4A	OR5B21	PDE4D	REEP1	PDE4C	PPP1R1B	REEP5	REEP4	REEP3	REEP2	REEP6	OR13A1	OR13H1	TRH	OR8D4	OR8D2	F2R	OR8D1	INSL5	OR6C70	F2	OR6C76	OR6C75	OR6C74	OR13G1	XCL2	XCL1	CX3CR1	OR6C65	OR8B8	OR8B4	OR6C68	OR13F1	OR8B3	PF4	OR8B2	OR5AU1	
NEGATIVE REGULATION OF FGFR1 SIGNALING%REACTOME%R-HSA-5654726.2	Negative regulation of FGFR1 signaling	MAPK3	PTPN11	FGF20	UBA52	FGF23	FGF22	CBL	MKNK1	UBB	SPRY2	UBC	FGF10	RPS27A	PPP2CA	PPP2CB	MAPK1	PPP2R1A	ANOS1	FRS2	FGF1	FGF2	FGF3	FGF4	FGF6	FGF9	BRAF	
SYNTHESIS OF UDP-N-ACETYL-GLUCOSAMINE%REACTOME%R-HSA-446210.2	Synthesis of UDP-N-acetyl-glucosamine	RENBP	NAGK	UAP1	GFPT1	PGM3	GNPNAT1	GFPT2	AMDHD2	
RNA POLYMERASE II HIV PROMOTER ESCAPE%REACTOME DATABASE ID RELEASE 74%167162	RNA Polymerase II HIV Promoter Escape	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	CCNH	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	TBP	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	GTF2A1	CDK7	GTF2A2	GTF2B	ERCC3	TAF9	TAF1L	AK6	ERCC2	GTF2E1	GTF2E2	TAF7L	MNAT1	TAF9B	TAF15	TAF12	TAF13	TAF10	
NOSTRIN MEDIATED ENOS TRAFFICKING%REACTOME%R-HSA-203641.1	NOSTRIN mediated eNOS trafficking	NOSTRIN	WASL	CAV1	DNM2	NOS3	
PTEN REGULATION%REACTOME%R-HSA-6807070.2	PTEN Regulation	PHC2	PHC1	TNRC6C	MOV10	UBA52	AGO3	PHC3	AGO4	AGO1	AGO2	TNRC6A	EZH2	TNRC6B	UBB	UBC	RING1	RPS27A	SUZ12	MAPK1	TNKS2	TNKS	PPARG	HDAC2	HDAC1	XIAP	SNAI1	SNAI2	MECOM	ATN1	MAF1	RPTOR	SLC38A9	STUB1	RRAGA	RRAGC	RRAGB	RHEB	PML	RRAGD	LAMTOR2	LAMTOR1	LAMTOR4	LAMTOR3	LAMTOR5	USP7	PSMD8	PSMD9	PSMD6	SALL4	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	MAPK3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PTEN	PSMD10	PSMB11	PSMD12	PSMD11	HDAC5	PSMD14	PSMD13	PSMB10	HDAC7	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CBX8	CBX6	HDAC3	CBX4	CBX2	CSNK2A1	CSNK2A2	NR2E1	BMI1	CSNK2B	CHD4	CHD3	MTOR	ATF2	REST	AKT2	AKT3	MTA1	MLST8	RBBP4	AKT1	RBBP7	MTA2	MTA3	MBD3	RNF2	GATAD2B	PREX2	TRIM27	GATAD2A	JUN	USP13	WWP2	RNF146	KDM1A	EGR1	NEDD4	MKRN1	FRK	OTUD3	EED	TP53	
LACTOSE SYNTHESIS%REACTOME%R-HSA-5653890.1	Lactose synthesis	SLC2A1	B4GALT1	LALBA	
TRISTETRAPROLIN (TTP, ZFP36) BINDS AND DESTABILIZES MRNA%REACTOME DATABASE ID RELEASE 74%450513	Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	EXOSC7	EXOSC6	EXOSC5	EXOSC4	EXOSC9	EXOSC8	EXOSC3	EXOSC2	EXOSC1	DCP1A	YWHAB	TNPO1	DIS3	XRN1	MAPKAPK2	DCP2	
HISTIDINE CATABOLISM%REACTOME DATABASE ID RELEASE 74%70921	Histidine catabolism	CARNS1	HAL	AMDHD1	FTCD	C9orf41	HNMT	UROC1	HDC	
DEFECTIVE RHAG CAUSES REGULATOR TYPE RH-NULL HEMOLYTIC ANEMIA (RHN)%REACTOME%R-HSA-5619042.1	Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN)	RHAG	
PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS%REACTOME DATABASE ID RELEASE 74%500657	Presynaptic function of Kainate receptors	GNGT1	GNGT2	GNG12	GNG11	GNG13	PLCB3	PLCB1	GRIK3	PLCB2	GNB2	GNB1	GNG3	GNB4	GNG10	GNB3	GNG2	GNB5	GNG5	GNG4	GNG7	GNG8	
SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL%REACTOME%R-HSA-1855167.2	Synthesis of pyrophosphates in the cytosol	IP6K3	IPPK	NUDT3	NUDT4	NUDT11	NUDT10	PPIP5K1	PPIP5K2	ITPK1	IP6K1	
IRS ACTIVATION%REACTOME DATABASE ID RELEASE 74%74713	IRS activation	INSR	IRS1	GRB10	INS	IRS2	
NUCLEOBASE BIOSYNTHESIS%REACTOME%R-HSA-8956320.1	Nucleobase biosynthesis	IMPDH2	PFAS	ATIC	PPAT	ADSL	CAD	ADSSL1	UMPS	GART	GMPS	ADSS	LHPP	PAICS	DHODH	IMPDH1	
HYDROXYCARBOXYLIC ACID-BINDING RECEPTORS%REACTOME DATABASE ID RELEASE 74%3296197	Hydroxycarboxylic acid-binding receptors	HCAR2	HCAR3	HCAR1	
DEFECTIVE RIPK1-MEDIATED REGULATED NECROSIS%REACTOME DATABASE ID RELEASE 74%9693928	Defective RIPK1-mediated regulated necrosis	TRAF2	CASP8	RIPK1	FADD	TRADD	
PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1%REACTOME%R-HSA-8849469.1	PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	RPS27A	CBL	AKT1	UBB	DOK1	UBC	ARAP1	UBA52	PTK6	
MATURATION OF PROTEIN M%REACTOME DATABASE ID RELEASE 74%9694594	Maturation of protein M	
SIGNALING BY HEDGEHOG%REACTOME DATABASE ID RELEASE 74%5358351	Signaling by Hedgehog	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY5	CSNK1A1	HHAT	WDR19	ITCH	VCP	UBA52	SEL1L	CUL1	ADRBK1	UBB	PRKAR2B	UBC	RPS27A	DERL2	GPC5	ERLEC1	OS9	CUL3	CDC73	SMURF2	SMURF1	IHH	SHH	ARRB1	ARRB2	DHH	PSMD8	DZIP1	SPOP	PSMD9	PSMD6	PSMD7	ADAM17	PSMD4	PSMD5	PSMD2	PSMD3	ULK3	PSMD1	SPOPL	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	SYVN1	PSMF1	EVC2	SHFM1	IQCE	EFCAB7	PSMB8	EVC	GAS8	PSMB9	PSMC5	PSMC6	PSMC3	NOTUM	PSMC4	PSMC1	PSMC2	P4HB	CDON	IFT172	PRKACG	PRKACB	DYNC2H1	RPGRIP1L	RBX1	IFT88	ADCY9	PRKAR1B	SMO	PRKAR1A	SCUBE2	DISP2	GPR161	INTU	KIF3A	PRKACA	PRKAR2A	GSK3B	BTRC	TTC21B	PTCH1	IFT122	FUZ	ADCY10	GNAS	SKP1	MKS1	GLI1	OFD1	GLI3	GLI2	IFT52	SUFU	IFT57	IFT140	KIF7	WDR35	HHIP	NUMB	BOC	ADCY4	GAS1	TULP3	ADCY3	
PI3K EVENTS IN ERBB2 SIGNALING%REACTOME%R-HSA-1963642.3	PI3K events in ERBB2 signaling	EREG	BTC	EGF	GAB1	NRG1	ERBB2	EGFR	NRG2	NRG3	NRG4	PIK3R1	PIK3CA	HBEGF	
OVARIAN TUMOR DOMAIN PROTEASES%REACTOME DATABASE ID RELEASE 74%5689896	Ovarian tumor domain proteases	IFIH1	RNF135	RIPK2	MAVS	OTUB1	OTUB2	UBE2D1	YOD1	PTEN	RIPK1	ZRANB1	TNIP1	TRAF3	VCP	TNIP3	TRAF6	RHOA	UBA52	TNFAIP3	OTUD7B	RNF128	DDX58	UBB	NOD1	NOD2	UBC	RPS27A	TNIP2	TRIM25	CDK1	OTUD7A	OTUD3	ESR1	OTUD5	IKBKG	APC	VCPIP1	TP53	
METABOLISM OF PROTEINS%REACTOME DATABASE ID RELEASE 74%392499	Metabolism of proteins	IFIH1	RNF135	MAVS	CFTR	VCP	SEL1L	ABCA3	EIF2S2	EIF2S1	EIF2S3	RNF185	KDM1B	PIGS	CPM	LY6K	APOA1	PIGU	PGAP1	PIGT	PIGO	DERL1	DERL2	PSCA	RNF5	GPAA1	PIGN	OS9	PIGP	PIGZ	PIGW	MSLN	PIGV	PIGY	PRSS21	PIGX	FCGR3B	PRND	TECTA	TECTB	CD52	PLAUR	RTN4RL2	IZUMO1R	ALPPL2	PIGC	DPM1	APEH	PIGB	DPM2	DPM3	USP8	NRN1L	CEACAM7	RTN4RL1	PIGA	CD109	CEACAM5	PIGK	LY6D	SPACA4	PIGM	PIGL	PIGG	LY6H	PIGF	GPLD1	PIGH	LY6E	NRN1	NTM	MFI2	TEX101	LYPD1	LYPD2	LYPD3	LYPD4	THY1	LYPD5	ART3	ART4	OTOA	LY6G6C	LY6G6D	OPCML	NTNG1	NTNG2	NEGR1	CNTN5	LSAMP	GP2	PLET1	BST1	VNN1	VNN2	RAET1G	VNN3	XPNPEP2	LYPD6B	RAET1L	ALPL	CNTN3	CNTN4	MDGA2	ULBP2	FOLR2	RECK	MDGA1	SPRN	KHSRP	DIS3	APLP2	PABPC1	DCP2	PARN	EXOSC7	SCG3	EXOSC6	EXOSC5	EXOSC4	EXOSC9	EXOSC8	EXOSC3	EXOSC2	EXOSC1	HSPA8	IGF2	IGF1	EIF4G1	ACTB	CALU	QSOX1	MYO5A	AHSG	SPP2	SLC34A2	BGLAP	PROZ	GAS6	ALG2	ALG11	RBX1	STAM	HGS	DNMT1	STAM2	DNMT3B	KLK3	XPC	RAD23A	IL33	PARK7	PARK2	GAPDHS	GFM1	TSFM	TUFM	SFTA3	SFTPB	SFTPC	SFTPD	PCNA	SFTPA2	SFTPA1	POLB	RUVBL1	CDC25A	NFRKB	HCFC1	INO80C	MDM2	INO80B	MDM4	INO80E	INO80D	INO80	BAP1	UCHL1	SENP8	ACTR5	ACTR8	UCHL3	FOXK2	FOXK1	TFPT	MBD5	MBD6	MCRS1	ADRM1	ASXL1	ASXL2	APP	UBE2D3	KDELR1	HSP90B1	RAB43	RAB41	KIF5B	KIF5A	AR	NFKB2	NSF	COG8	B4GALT2	COG7	B4GALT3	COG6	COG5	COG4	COG3	COG2	IKBKE	COG1	RIPK2	DYNC1LI1	RAB30	DYNC1LI2	RAB36	B4GALT4	KDELR2	KDELR3	TRAF3	COPB2	COPA	TMED10	COPB1	TGOLN2	BIRC2	BIRC3	NRIP1	MAN2A2	MAN2A1	NOD1	NOD2	RING1	RAB6A	RAB6B	ACTL6A	RAB39A	TNIP2	SAA1	COPE	ARF3	ARF4	ARF1	MEN1	CAPZB	MAN1A2	USP9X	TMED3	TMED2	MAN1A1	TMED7	TFAP2B	TMED9	TFAP2C	COPZ2	ARFGAP3	UBA3	DYNLL2	BET1L	ARFGAP1	ACE2	RORA	COPZ1	RAB33B	ARFGAP2	SEC22B	ARF5	DCTN6	NAPA	DCTN5	NAPB	DCTN1	DCTN4	GOSR2	GOSR1	NAPG	FOXO4	MAN1C1	ATXN3	STX5	YKT6	GSK3A	DYNC1I1	ACADVL	FKBP14	SRPR	GALNT2	MYDGF	GALNT1	GBF1	TATDN2	ARCN1	SERP1	CREB3L4	CREB3L1	CAPZA3	CREB3L2	TSPYL2	DDX11	CAPZA1	WIPI1	CAPZA2	PDIA6	RAB18	PDIA5	FBXO32	ERN1	CREB3	RAB9A	DCSTAMP	CTDSP2	COPG2	DNAJB11	COPG1	PREB	ACTR10	CUL7	CXXC1	ADD1	RAB9B	EXTL2	EXTL1	LMNA	SSR1	DNAJB9	EXTL3	SULT1A3	SEC31A	ZBTB17	KLHDC3	WFS1	EDEM1	GFPT1	SYVN1	YIF1A	CREBRF	SRPRB	HYOU1	HDGF	TPP1	TRIM28	L3MBTL2	BMI1	SATB2	ST6GALNAC1	CMAS	MPI	GMPPB	NANP	FPGT	GMPPA	PGM3	NPPA	GNPNAT1	NANS	NUDT14	ST6GAL2	ALG5	GNGT1	RENBP	DHDDS	GNGT2	MVD	ST6GALNAC5	VDR	GNAT2	ST6GALNAC6	GNE	TSTA3	UAP1	NPL	FUOM	NEU2	NEU3	NEU4	RNF2	GMDS	AMDHD2	NEU1	SLC17A5	GNG3	ST8SIA4	ST8SIA5	GNG10	ST3GAL5	GNG2	ST3GAL6	ST8SIA6	FUK	GNG5	GNG4	CTSA	GNG7	NUS1	GNG8	PMM1	ST8SIA1	ST8SIA2	TCF7L2	GFPT2	SRD5A3	ST8SIA3	PMM2	DOLK	NAGK	PHC2	GLB1	DOLPP1	PHC1	GNG12	GNG11	GNG13	GNAO1	PHC3	GNB2	GNB1	GNB4	GNB3	CTNNB1	GNB5	ZNF350	VCAN	TNKS2	TNKS	ARSB	WRN	LTBP1	BMP4	RHOA	PGR	STAT3	HDAC4	SHC1	HDAC7	KCTD6	CBX8	SMAD1	CBX4	CBX2	YARS	NR4A2	CARS	DARS	THRB	WARS	VARS	TARS	SARS	EPRS	NARS	AIMP1	AIMP2	QARS	KARS	PPA1	THBS1	NR2C1	LARS	MARS	RARS	GARS	HARS	IARS	EEF1E1	FARSA	FARSB	AARS	VGF	VDAC3	VDAC2	VDAC1	TTLL10	TUBB8P12	TPGS1	TTL	TPGS2	TUBB8	TUBA3E	TUBA1C	TUBB6	TUBA1B	TUBB3	TUBB1	AGTPBP1	LRRC49	RPL4	NICN1	EIF4A2	TTLL7	EIF4A1	RPL5	AGBL5	CDC73	RPL30	AGBL4	TTLL6	UBE2L3	RPL3	TTLL5	RPL32	RNF152	SHPRH	TUBB2B	RPL31	TTLL4	PEX2	RPL34	TUBB2A	RPL10L	RNF40	RNF144A	TTLL3	RPL8	RPL10A	AGBL1	WAC	TTLL2	UBE2V2	RPL9	VIMP	RPL6	AGBL3	PRKDC	TTLL1	RPL7	RPS15	CTR9	AGBL2	FUCA2	WDR61	RPS14	TTLL11	RPS17	RTF1	TTLL12	RPS16	TTLL9	UBE2J2	HLTF	RPL18A	TTLL8	RPS19	TMEM129	RPL36AL	LEO1	RPS18	RNF20	UBE2B	RPL36	PEX10	RPL35	UBE2A	RPL38	PEX12	RPL37	PEX13	RPS11	PEX14	RPL39	RPS10	RNF181	RPS13	PAF1	RPS12	RAD18	FBXO27	RPS9	RPL21	FBXO21	RPS7	FBXO22	EIF1AX	RPS8	FBXW8	RPL23	RPS5	FBXO17	RPL22	FBXO15	RPS6	FBXO10	RPSA	FBXO11	RPL24	RPL27	RPL26	RPL29	RPL28	FBXO44	RPS4Y2	FBXO41	RPS4Y1	FBXO40	EIF4EBP1	EIF2B5	FBXO30	RPL39L	FBXO31	EIF2B4	EIF2B3	RPL41	N6AMT1	EIF2B2	RPL3L	RPS26	RPS25	RPS28	EIF5	RPS27	RPS29	MAT2B	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	TSPAN14	RPLP2	EIF2B1	EIF5B	RPL13A	RPS3A	RPL37A	RPL10	RPL12	FBXO7	RPL11	RPL36A	FBXO9	RPS27L	RPS15A	FBXO2	RPL14	RPS3	EIF4H	RPL13	RPL15	RPS2	RPL18	RPL17	EIF4E	EIF4B	FBXL8	RPL19	FBXL4	RPL35A	RPL23A	EIF3M	FBXL7	EIF3K	EIF3L	EIF3I	EIF3J	EIF3G	EIF3H	EIF3E	GAN	RPL22L1	EIF3F	KLHL2	FAU	EIF3C	KLHL3	EIF3D	KLHL9	EIF3A	KLHL5	SEMG1	RPL26L1	EIF3B	OTUD5	TOMM20	SRP14	UBE2Z	LONP2	FBXW12	UBA6	UBE2F	UBE2H	UBE2W	UBA1	SMAD2	UBE2K	SMAD3	TGFB1	TGFBR1	TGFBR2	ASB13	ASB14	ASB11	RNF7	ASB12	ASB17	ASB18	ASB15	ASB16	ASB10	IDE	TDG	SEC61G	SEC61B	RAB7A	MGAT3	RAB3D	RAB44	APH1A	APH1B	RAB37	EP300	PSENEN	KBTBD13	FBXL22	FBXL20	RAB24	FBXL19	FBXL18	FBXL15	TOMM70A	FBXL16	FBXL13	FBXL14	FBXL12	CLSPN	GALNT12	MUCL1	OGT	MUC17	GPR75-ASB3	MUC5B	MUC3A	MUC5AC	CST3	MUC1	MUC7	MUC12	MUC13	KBTBD6	MUC15	MUC20	KBTBD8	MUC4	MUC21	LMO7	MUC6	SATB1	GSN	LTF	LYZ	CAMKMT	LRRC41	SPSB2	SPSB1	SPSB4	UBE2E3	ZBTB16	CECR1	LRR1	CCNF	KEAP1	COMMD9	AGT	BPIFB2	CTSH	COMMD3	CALR	UBE2G1	UBE2G2	PARP1	DNAJC3	CANX	KLHL41	KLHL42	KLHL11	KLHL13	KLHL25	KLHL21	SPTAN1	KLHL22	ANK2	KLHL20	ANK3	ANK1	SPTB	SEC61A2	SPTBN4	SEC61A1	SPTBN5	UBE2Q2	INS	SPTA1	CD59	CD55	SPTBN1	UBE2R2	SPTBN2	TMEM115	GOLGB1	FOLR1	BET1	ASB8	ASB9	ASB6	ASB7	ASB4	ASB5	ASB2	ASB1	WSB1	RNF123	ISL1	UBE2D1	SKP2	UBE2E1	CCNA2	PPARGC1A	CCNA1	CCNE2	CCNE1	BTBD1	BTBD6	UBE2C	UBE2S	PPARG	PPARA	KCTD7	YY1	ANO8	CKAP4	ETF1	BABAM1	HERC2	UIMC1	UBE2D2	RNF168	BRCC3	CDC34	TP53BP1	TRAF6	BRE	FAM175A	UBE2N	STX1A	TAB1	EPAS1	SDC2	GSPT2	GSPT1	HLA-A	B2M	DPAGT1	ALG8	NCOA1	ALG9	ALG6	NCOA2	ALG14	ALG3	ALG13	ALG12	ALG1	MPDU1	RFT1	NR5A1	RXRA	TRAF2	RIPK1	KLK13	FN1	BECN1	UFD1L	CREBBP	TCEB2	TCEB1	MYC	HNRNPK	HNRNPC	HIF3A	STS	DPH1	DPH2	ARSJ	DPH3	ARSK	ARSH	ARSI	PAX6	DPH5	NCOR2	ARSF	RRAGA	DPH6	ARSG	DPH7	RARA	ARSD	ARSE	FN3K	ARSA	FN3KRP	SUMF2	SUMF1	TPST2	DDX5	TPST1	GGCX	PCGF2	SEMA5A	CDH2	INHBB	INHBA	FSTL3	CUL2	RARS2	AARS2	MARS2	PARS2	DARS2	YARS2	HARS2	WARS2	FARS2	LARS2	WDR5	SARS2	CES1	NARS2	IARS2	TARS2	VARS2	CARS2	EARS2	HDAC3	MBOAT4	PLA2G7	RBBP5	KLF4	LEP	DAG1	SERPINC1	PROS1	KNG1	FGA	F10	SERPIND1	FGG	F2	DCAF8	F5	DCAF5	F7	DCAF4	DCAF6	WSB2	OBSL1	F8	SIAH2	DCUN1D5	F9	SIAH1	DCUN1D3	PROC	DCUN1D4	DCUN1D1	DCUN1D2	COMMD8	PUM2	DDA1	SLC34A1	ANKRD9	UBXN7	COMMD2	COMMD1	COMMD6	COMMD7	SOCS6	COMMD4	COMMD5	SPSB3	CCDC8	CUL9	UBD	NAE1	WDTC1	CCDC22	COMMD10	DTL	TULP4	DCAF16	CPA3	DCAF17	FEM1C	ENPEP	ACE	DCAF10	CPB1	DCAF11	FEM1A	MME	FEM1B	ATP6AP2	C9orf3	NEURL2	GZMH	ANPEP	REN	MANEA	SUZ12	SMAD4	USP33	MKL1	USP30	POFUT2	GYLTL1B	B3GALNT2	POMGNT2	POMK	ADAMTS2	ADAMTS3	ADAMTS14	USP10	XRCC4	CUL5	TLN1	TGFA	SMC3	RCE1	ICMT	CDCA8	RAD21	TNC	AREG	STAG1	STAG2	RANGAP1	SMC1A	INCENP	BIRC5	AURKB	FBN1	USP17L2	KBTBD7	CUL3	ARL2	CSF2RB	CSF2RA	USP15	FGF23	SMURF2	UCHL5	SMAD7	UBE2M	GALNT3	EID3	SPARCL1	HRC	JOSD2	PML	JOSD1	PTRH2	ARRB1	FSTL1	ARRB2	GOLM1	MBD1	ATXN3L	MUL1	ATXN7	SP3	BMP15	FOXL2	PPP2R5B	NSMCE4A	ITIH2	UHRF2	LGALS1	NSMCE2	NSMCE1	MXRA8	SNX3	ZBED1	B4GALNT2	OTUD7A	CHRDL1	RAB22A	KIN	ENAM	MFGE8	STAMBPL1	VCPIP1	UBE2T	CSF1	FAM175B	UBA2	MYSM1	VCPKMT	RCN1	OTUB1	OTUB2	RAB40A	RAB40B	RAB40C	TNIP1	TNIP3	SOCS5	SMC5	SMC6	USP17L4	USP17L5	EVA1A	USP17L8	CHGB	DDX17	RNF128	ALG10B	TADA2B	NPM1	ZNF131	WDR48	SERPINA10	PRSS23	ASGR1	ASGR2	UBXN1	NGLY1	WDR20	AFP	RNF139	METTL21A	MLEC	NDNL2	UGGT2	USP17L3	UGGT1	KTN1	PDIA3	EDEM3	USP17L1	NUCB1	AMFR	NOTUM	MARCH6	EEF1B2	RAB3B	RAD23B	EEF1A1	RAB3C	RNF103	TRIM13	EEF1G	N6AMT2	EEF1D	RAB42	ENGASE	EEF1A2	RAB2B	EEF2	IGFBP5	USP5	IGFBP4	USP3	MITF	HIC1	RAB34	FKBP8	STAMBP	AMBN	TMEM132A	TADA3	CYR61	METTL10	MEPE	PTP4A2	METTL22	METTL20	RAB20	RAB25	RAB26	RAB23	EEF2KMT	RAB29	RAB15	RAB19	RAB17	USP17L30	YOD1	UMOD	STC2	ZRANB1	PRMT3	TOPORS	POMT2	SPON2	FAM20C	VWA1	SEMA5B	SPON1	FAM20A	THSD7B	USP17L27	POMT1	USP17L26	C3	USP17L29	ADAMTSL1	USP17L28	C1GALT1C1	USP17L21	C4A	ADAMTSL4	USP17L20	ADAMTSL3	USP17L22	ADAMTSL2	USP17L25	THSD7A	USP17L24	ADAMTS6	USP17L15	ADAMTS7	USP17L18	SBSPON	USP17L17	POMGNT1	USP17L19	ADAMTS20	P2RY2	USP17L10	B3GLCT	USP17L12	THBS2	USP17L11	CFP	USP17L13	ADAMTS12	SHISA5	THSD1	ALG10	ADAMTS10	SCG2	THSD4	AMELX	ADAMTS15	SAE1	ADAMTS13	USP37	ADAMTS19	SENP5	LARGE	USP47	ADAMTS17	USP48	C1GALT1	USP49	B4GAT1	USP42	USP44	SAFB	SENP2	SENP1	AMTN	USP14	USP16	USP12	USP19	USP24	USP25	USP26	USP4	RWDD3	USP2	USP20	USP22	USP28	ZDHHC2	DMBT1	LMCD1	NAPSA	CCDC59	DCAF7	PGA3	CCT6B	PGA5	KIF13A	PGA4	FBXO4	FBXO6	ADGRF5	RGS9	RGS6	RGS7	FBXW4	FBXW5	CYLD	FBXW10	TNFAIP3	FBXW7	OTUD7B	VBP1	SPHK1	FBXW9	TUBA4B	FBXW2	PFDN1	PFDN2	FKBP9	CCT3	PFDN4	PFDN5	PFDN6	CCT2	TUBAL3	USP11	GBA	AP3M1	CCT7	ARFGEF2	CCT6A	PDCL	FBXL3	TCP1	SKIV2L	RGS11	TUBA8	CCT8	WRAP53	CCT5	CCT4	USP21	OTULIN	PCSK1	CDX2	GRP	GPR119	DPP4	SPCS3	SPCS2	SPCS1	FFAR4	FFAR1	SEC11A	SEC11C	CUL4A	DDB1	CUL4B	DMP1	MATN3	ETFB	TAF9B	TAF10	LAMB2	DNMT3A	GFM2	MTRF1L	MRRF	ADORA2A	CTBP1	TP53	GATA6	GATA4	GATA3	CBX5	RAB5A	SIN3A	HDAC2	HDAC1	BARD1	RAD52	RFWD2	TFG	RAB4B	COPS7B	COPS7A	PCSK9	GNAT3	LHB	TXN	CREB3L3	CRHR2	CGA	APOA2	SERPINA1	TRRAP	APOA4	APOA5	FSHB	SAR1B	GNAI3	VAMP2	GNAI1	GNAI2	GPS1	GGA2	APOE	LMAN1	USP34	APOB	GGA1	GGA3	AXIN2	GPIHBP1	LMAN2	MBTPS1	CHML	APOL1	NR1H2	TRAPPC10	RAB3A	GNAZ	RAB32	RAB31	ALB	RAB35	P4HB	RAB38	MBTPS2	RAB5B	NLRP3	RAB5C	ANKRD28	TRAPPC2	SEC16B	TRAPPC3	RAB4A	TSHB	TRAPPC1	ADORA2B	CETN2	CCP110	TRAPPC4	SEC16A	POMC	ACTR1A	TRAPPC5	TUBA1A	TRAPPC9	COPS4	COPS3	BTRC	COPS6	COPS5	CNIH1	RAB8A	COPS2	SKP1	COPS8	CNIH2	FBXW11	CNIH3	MCFD2	PPP6C	CSNK1D	PPP6R1	PPP6R3	DYNLL1	SEC22A	TUBA4A	SEC22C	SEC23A	RAB21	UBA52	SEC24B	SEC24A	DYNC1I2	DCTN2	RAB10	DCTN3	CUL1	RAB14	AURKA	RAB12	UBB	RAB13	SEC24D	SEC24C	UBC	BRCA1	RPS27A	LMAN1L	BLM	DYNC1H1	LMAN2L	SCFD1	RPA1	TUBB4B	TUBB4A	INHA	INHBC	CDK1	INHBE	RAB39B	RAB27A	RAB27B	CTSZ	MIA2	MDC1	MIA3	CEBPB	CXCL8	CEBPG	CTSC	HERPUD1	RAB8B	CCL2	PCSK2	IGFBP1	ERO1LB	KIF5C	RAB33A	HSPA5	NFYA	SLC30A7	NFYB	SLC30A6	RAB7B	NFYC	DAXX	SLC30A8	EIF2AK3	SLC30A5	MYRIP	ASNS	DDIT3	TMEM27	STX17	ATF6	CPE	ATF3	ATF4	RAB11B	SEC23IP	CDC20	CHM	TRAPPC2L	ING2	TBC1D20	DDB2	IL6	HIPK2	USP7	IGFBP3	TRAPPC6A	ST6GALNAC2	RPN2	PRKCSH	TUSC3	RPN1	MAGT1	TRAPPC6B	GANAB	FUT8	MGAT5	ST3GAL4	PTEN	MGAT1	MGAT2	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	RABGGTB	EDEM2	RABGGTA	MOGS	DDOST	MGAT4C	DAD1	TOP2B	MGAT4A	SUMO3	MGAT4B	SUMO2	STT3A	PIAS4	MAN1B1	PIAS3	ST6GALNAC3	TOP1	ST6GALNAC4	CPB2	CSNK2A1	CSNK2A2	SLC35A1	SLC35C1	CSNK2B	ALPI	TRIM27	GALNT11	GALNT14	USP13	ACHE	GALNT13	RNF146	GALNT16	GALNT15	GALNT18	B3GNTL1	OTUD3	GALNT10	GALNT9	GALNT8	B3GNT9	WBSCR17	B3GNT8	B3GNT7	B3GNT6	B3GNT5	B3GNT4	B3GNT3	B3GNT2	CHST4	PLA2G4B	B4GALT6	B4GALT5	GCNT1	GCNT3	GCNT4	GCNT7	GALNT7	GALNT6	GALNT5	GALNT4	A4GNT	GALNTL5	GALNTL6	GRIA1	EIF5A	EIF5A2	DHPS	DOHH	BCHE	HIST2H2AB	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	HIST1H2AI	HIST1H2AH	HIST1H2AK	HIST2H2BF	HIST3H2A	GPC3	PNPLA2	MRPS17	MTFMT	MRPS15	MRPS16	MRPS14	MRPS11	MRPS12	MRPL38	MRPL39	MRPS10	MRPL36	MRPL37	MRPL34	MRPL35	MRPL32	MRPL33	MRPL41	MRPL4	MRPL42	MRPL3	MRPL2	MRPL1	MRPL40	MRPL9	CHCHD1	MRPS28	MRPS26	MRPS27	MRPS24	MRPS25	MRPS22	MRPS23	MRPL49	MRPS18B	MRPS2	MRPS18A	MRPL47	MRPL48	MRPS7	MRPL45	MRPS6	MRPL46	MRPL43	MRPS5	MRPS18C	MRPL44	MRPL52	OXA1L	MRPL53	MRPL50	MRPS9	MRPL51	AURKAIP1	DAP3	MRPS35	MRPS36	MRPL18	MRPS33	MRPS34	MRPL19	MRPL16	MRPS31	MRPL17	MTIF2	MRPL14	MRPS30	MTIF3	MRPL15	MRPL12	MRPL13	MRPL57	MRPL10	MRPL54	MRPL11	MRPL55	MRPL20	ICT1	GADD45GIP1	PTCD3	MRPL27	MRPL28	ERAL1	MRPL23	MRPL24	MRPL21	MRPL22	MRPL30	IGFBP2	PAPPA	IGFALS	KLK1	IGFBP6	PAPPA2	NUP107	NUP188	GOLGA2	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	RAB2A	NUP214	NUP210	HIST1H2AJ	NUP93	XRN2	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	NUP205	POM121	H2AFB1	TRMT112	CHD3	HIST1H3J	TTF1	AAAS	NUP160	MTA1	HIST1H3A	NUP85	TPR	PRL	HIST1H3F	HIST1H3G	NUP88	GH1	HIST1H3H	RBBP7	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	NUP155	H3F3B	HIST1H4K	HIST1H4L	KAT2B	H3F3A	NUP153	KAT2A	SRP19	H2BFS	CISH	HIST1H4A	TRAM1	SOCS2	SRP54	HIST1H4B	SSR4	HIST1H4H	SSR2	HIST1H4I	SSR3	HIST1H4J	SRP9	HIST1H4C	SRP72	HIST1H4D	SRP68	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	HIST2H2AC	NUP62	NDC1	SEC13	NUP133	H2AFZ	H2AFX	HIST2H2BE	HIST4H4	NUP50	GORASP1	NUP54	DCAF13	NOP56	HIST1H2BN	NOP58	HIST1H2BM	RAB1A	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	RAB1B	USO1	HIST1H2BK	HIST2H4A	HIST2H4B	ERCC8	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	B4GALT1	UCN	EXOC8	EXOC7	GIP	IAPP	RAB11A	CALCA	EXOC4	EXOC3	EXOC6	EXOC5	EXOC2	PSMD8	EXOC1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	HIF1A	AXIN1	PSMD1	IKBKG	APC	MAP3K7	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	TBCD	GCG	TBCC	PSMD10	TBCB	PSMB11	TBCA	ERO1L	PSMD12	TBCE	PSMD11	TOP2A	PSMD14	PSMD13	BCL10	PSMB10	PSMA7	RELA	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	APCS	PSMC4	ODAM	PSMC1	TSPAN33	PSMC2	SORL1	TSPAN15	MSRA	NAT8	SNCAIP	SNCA	TSPAN5	NR3C2	CALB1	PCMT1	BACE1	SUMO1	MSRB2	MSRB3	UBE2I	MSRB1	ITM2B	TGFBI	ESR1	VHL	SOCS3	PIAS1	CHST8	FUCA1	CHST10	FUT3	ATP6V0D1	NEDD8	CAND1	PENK	GNAT1	CP	TF	FBXL5	IGFBP7	UBE2L6	TRIM25	TTR	SP100	COL7A1	DDX58	USP18	CDKN2A	ADAM10	HSPG2	KLK2	ADAMTS16	NCSTN	ADAMTS18	LAMC1	ADAMTS4	ADAMTS5	ADAMTS1	ADRB2	CTSG	TIMP1	ADAMTS8	CTSD	ADAMTS9	MMP1	MMP2	ADRA2C	ADRA2A	PLG	FURIN	SPP1	CMA1	LAMB1	NR3C1	PPA2	RHOT1	SUDS3	
RORA ACTIVATES GENE EXPRESSION%REACTOME DATABASE ID RELEASE 74%1368082	RORA activates gene expression	CPT1A	RXRA	TBL1X	TBL1XR1	RORA	MED1	TGS1	SREBF1	HELZ2	NCOA1	PPARA	NCOA2	CHD9	NCOA6	CREBBP	SMARCD3	EP300	CARM1	
TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST%REACTOME DATABASE ID RELEASE 74%6804114	TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	SFN	ZNF385A	PCNA	BAX	PRMT1	CDC25C	CDK1	RBL2	RBL1	E2F4	AURKA	TFDP1	TFDP2	CCNB1	GADD45A	EP300	CARM1	TP53	
AMPLIFICATION OF SIGNAL FROM UNATTACHED KINETOCHORES VIA A MAD2 INHIBITORY SIGNAL%REACTOME%R-HSA-141444.2	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	RCC2	DYNLL1	DYNC1LI1	NDC80	ZWINT	CKAP5	DYNC1LI2	AHCTF1	SGOL2	ZW10	SGOL1	RPS27	NUF2	MAPRE1	SPDL1	SEC13	NDEL1	NUP133	NUDC	RANGAP1	PAFAH1B1	INCENP	BIRC5	DYNC1I2	ITGB3BP	MIS12	CENPA	XPO1	AURKB	NSL1	CENPC	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	PPP2CA	KIF18A	CENPN	CLASP1	CENPO	PPP2CB	B9D2	CENPP	DYNC1H1	CENPQ	NUP43	SPC24	SPC25	RANBP2	NDE1	PLK1	CLIP1	NUP37	PPP1CC	NUP107	PPP2R1B	DYNLL2	KIF2A	KIF2C	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	NUP160	NUP85	PPP2R1A	CLASP2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	ERCC6L	PPP2R5C	ZWILCH	CASC5	KNTC1	MAD1L1	CDCA8	DYNC1I1	PMF1	SKA1	SKA2	DSN1	CENPE	
REGULATION OF GAP JUNCTION ACTIVITY%REACTOME DATABASE ID RELEASE 74%191650	Regulation of gap junction activity	TJP1	GJA1	
ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE%REACTOME DATABASE ID RELEASE 74%2485179	Activation of the phototransduction cascade	GNGT1	GNB1	CNGA1	PDE6G	CNGB1	SAG	RHO	PDE6B	PDE6A	SLC24A1	GNAT1	
SYNTHESIS OF PI%REACTOME DATABASE ID RELEASE 74%1483226	Synthesis of PI	CDS1	CDIPT	PITPNM1	PITPNM3	PITPNM2	
RETINOID METABOLISM DISEASE EVENTS%REACTOME%R-HSA-6809583.1	Retinoid metabolism disease events	RBP4	
DEFECTIVE SLC34A2 CAUSES PALM%REACTOME%R-HSA-5687583.2	Defective SLC34A2 causes PALM	SLC34A2	
SIGNALING BY RETINOIC ACID%REACTOME%R-HSA-5362517.2	Signaling by Retinoic Acid	ALDH1A1	RXRA	RDH14	RDH13	RDH16	ALDH8A1	RDH5	PDHA2	PDHA1	CPT1B	RARG	FABP5	RXRB	RXRG	PDK4	PDK3	PDK2	PDK1	DHRS3	CPT1A	RARA	PDHB	RARB	PPARD	CRABP2	DLAT	DLD	ADH1C	ADH1A	AKR1C3	CRABP1	DHRS4	ALDH1A3	CYP26A1	ADH4	SDR16C5	DHRS9	CYP26B1	RDH11	PDHX	CYP26C1	RDH10	ALDH1A2	
DEFECTIVE SLC6A19 CAUSES HARTNUP DISORDER (HND)%REACTOME DATABASE ID RELEASE 74%5659735	Defective SLC6A19 causes Hartnup disorder (HND)	SLC6A19	
ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE%REACTOME%R-HSA-264642.3	Acetylcholine Neurotransmitter Release Cycle	RIMS1	BZRAP1	UNC13B	RAB3A	PPFIA1	PPFIA4	PPFIA3	PPFIA2	SYT1	SLC5A7	SLC18A3	CPLX1	CHAT	STX1A	SNAP25	VAMP2	
WAX AND PLASMALOGEN BIOSYNTHESIS%REACTOME%R-HSA-8848584.3	Wax and plasmalogen biosynthesis	AWAT1	AWAT2	AGPS	GNPAT	DHRS7B	FAR1	FAR2	
VITAMINS%REACTOME DATABASE ID RELEASE 74%211916	Vitamins	CYP27B1	CYP26A1	CYP2R1	CYP26B1	CYP24A1	CYP26C1	
LYSOSOME VESICLE BIOGENESIS%REACTOME%R-HSA-432720.2	Lysosome Vesicle Biogenesis	DNAJC6	HGS	DNM2	DNASE2	CHMP2A	CLVS2	CLVS1	CLTB	SH3GL2	AP4S1	TXNDC5	APP	BLOC1S1	M6PR	ARRB1	AP1G1	AP1B1	AP1S2	AP1S1	ARF1	AP1S3	HSPA8	CLTC	CLTA	AP1M2	AP1M1	AP4B1	GNS	VAMP8	CTSZ	AP4M1	VAMP7	AP4E1	AP1G2	VAMP2	
DEFECTIVE HLCS CAUSES MULTIPLE CARBOXYLASE DEFICIENCY%REACTOME DATABASE ID RELEASE 74%3371599	Defective HLCS causes multiple carboxylase deficiency	MCCC1	ACACA	PCCA	PCCB	HLCS	PC	MCCC2	
PLCG1 EVENTS IN ERBB2 SIGNALING%REACTOME DATABASE ID RELEASE 74%1251932	PLCG1 events in ERBB2 signaling	ERBB2	EGFR	PLCG1	EGF	
DEFECTIVE GCLC CAUSES HEMOLYTIC ANEMIA DUE TO GAMMA-GLUTAMYLCYSTEINE SYNTHETASE DEFICIENCY (HAGGSD)%REACTOME DATABASE ID RELEASE 74%5578999	Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)	GCLC	GCLM	
DDX58 IFIH1-MEDIATED INDUCTION OF INTERFERON-ALPHA BETA%REACTOME DATABASE ID RELEASE 74%168928	DDX58 IFIH1-mediated induction of interferon-alpha beta	IFIH1	IFNA10	RNF135	MAVS	SIKE1	UBE2D2	NLRC5	PIN1	UBE2D1	TBK1	IRF3	ITCH	TRAF3	TRAF6	IRF7	UBA52	IFNA21	CYLD	TNFAIP3	RELA	UBB	IFNA5	CASP10	IFNA4	TANK	UBC	IFNA7	IFNA6	RPS27A	MAP3K1	NFKB1	IFNA1	S100B	UBE2L6	NFKBIA	SAA1	IFNA2	IFNA8	HERC5	ISG15	TAX1BP1	TRIM25	NFKBIB	PCBP2	OTUD5	IFNB1	TRAF2	CASP8	UBA7	RIPK1	FADD	UBE2K	DDX58	NLRX1	RNF216	ATG5	APP	UBE2D3	RNF125	ATG12	AGER	DHX58	S100A12	IKBKB	NFKB2	HMGB1	IFNA13	CREBBP	NKIRAS1	EP300	IFNA14	NKIRAS2	IFNA16	IKBKG	IFNA17	TKFC	IKBKE	CHUK	
HATS ACETYLATE HISTONES%REACTOME%R-HSA-3214847.1	HATs acetylate histones	HIST2H2AC	SAP130	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	OGT	ACTL6A	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H2AB	HIST2H4B	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	HIST1H2AI	HIST1H2AH	KAT8	HIST1H2AK	KAT7	HIST2H2BF	SUPT20H	HIST3H2A	ATXN7L3	CSRP2BP	TADA2A	ZZZ3	IKBKAP	ING4	ING3	PAX3	SUPT3H	TAF6L	CCDC101	BRD8	ELP2	ELP3	ELP4	ELP5	ELP6	JADE1	JADE3	YEATS4	JADE2	SUPT7L	MORF4L1	KAT6B	MORF4L2	HAT1	ENY2	TAF5L	MEAF6	MBIP	DMAP1	DR1	MRGBP	YEATS2	TADA1	VPS72	MSL2	MSL3	MSL1	KANSL1	KANSL2	KANSL3	ING5	BRD1	CLOCK	ATXN7	TAF9	KAT6A	AK6	TAF12	BRPF1	TAF10	BRPF3	PHF20	RUVBL1	HCFC1	RUVBL2	TADA2B	MCRS1	WDR5	TRRAP	ACTB	EPC1	NCOA1	EP400	TADA3	NCOA2	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	HIST1H3J	ATF2	HIST1H3A	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	RBBP7	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	HIST1H4K	HIST1H4L	KAT2B	KAT2A	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	CREBBP	HIST1H4J	EP300	HIST1H4C	USP22	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
SHC1 EVENTS IN ERBB2 SIGNALING%REACTOME%R-HSA-1250196.4	SHC1 events in ERBB2 signaling	PRKCE	PRKCA	EREG	SHC1	BTC	EGF	NRG1	ERBB2	EGFR	NRG2	NRAS	NRG3	SOS1	NRG4	HRAS	PRKCD	PTPN12	HBEGF	
TRANSCRIPTIONAL REGULATION BY RUNX3%REACTOME DATABASE ID RELEASE 74%8878159	Transcriptional regulation by RUNX3	PSMA6	PSMA3	CDKN1A	PSMA4	PSMA1	PSMA2	CBFB	PSME3	BCL2L11	PSME1	MAML3	PSME2	MAMLD1	PSMD10	MDM2	HDAC4	UBA52	PSMD12	KRAS	PSMD11	PSMD14	NOTCH1	PSMD13	ITGAL	PSMB10	PSMA7	CTNNB1	TEAD2	PSMB6	PSMB7	TEAD3	PSMB4	UBB	TEAD4	PSMB5	BRD2	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	MYC	PSMC6	FOXO3	PSMC3	RUNX3	PSMC4	PSMC1	WWTR1	PSMC2	SNW1	SPP1	YAP1	SRC	ITGA4	CTGF	SMAD4	SMURF2	SMAD3	SMURF1	TGFB1	TEAD1	RUNX1	ZFHX3	CDKN2A	CCND1	LEF1	TCF7	MAML2	MAML1	KAT2B	PSMD8	RBPJ	KAT2A	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	CREBBP	PSMD3	EP300	PSMD1	HES1	TCF7L2	PSMA5	TP53	TCF7L1	JAG1	
INTESTINAL INFECTIOUS DISEASES%REACTOME%R-HSA-8942233.1	Intestinal infectious diseases	GUCY2C	PDZD3	
RESPIRATORY ELECTRON TRANSPORT, ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING, AND HEAT PRODUCTION BY UNCOUPLING PROTEINS.%REACTOME%R-HSA-163200.1	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	SDHC	SDHD	SDHA	SDHB	MT-ND6	NDUFA13	MT-ND4	MT-ND5	NDUFA11	MT-CO1	NDUFA12	TACO1	NDUFA10	COX6A1	MT-ND2	MT-ND3	MT-ND1	COX6B1	COX7A2L	SCO1	SCO2	UQCRC1	MT-CO2	UQCRC2	MT-CO3	TMEM126B	COX19	COX16	NDUFB10	UQCRB	NDUFB11	PM20D1	COX18	UQCRH	COX11	COX14	NDUFV3	CYC1	NDUFV2	NDUFV1	TRAP1	SURF1	NDUFAF6	NDUFAF7	UQCRQ	NDUFAF4	NDUFAF5	NDUFAF2	CYCS	NDUFAF3	NDUFAF1	MT-CYB	COX20	COX7B	COX4I1	ETFA	ETFB	ECSIT	COX7C	UQCRFS1	COX8A	ACAD9	NDUFC2	NDUFC1	COQ10B	COQ10A	NDUFS8	NDUFS7	NDUFS6	NDUFS5	NDUFS4	NDUFS3	NDUFS2	NDUFS1	NDUFB9	NDUFB8	NDUFB7	NDUFB6	NDUFB5	NDUFB4	NDUFB3	ETFDH	NDUFB2	NDUFB1	UQCR11	UQCR10	COX5B	COX5A	NDUFA9	NDUFA8	NDUFA7	TIMMDC1	NDUFA6	NDUFA5	NUBPL	NDUFA4	NDUFA3	NDUFA2	NDUFA1	COX6C	LRPPRC	NDUFAB1	ATP5S	ATP5A1	ATP5C1	ATP5J	ATP5I	ATP5H	ATP5G3	ATP5G2	ATP5O	ATP5G1	ATP5L	MT-ATP6	ATP5B	ATP5E	ATP5D	ATP5F1	MT-ATP8	ATP5J2	SLC25A27	UCP3	UCP2	UCP1	SLC25A14	
VPR-MEDIATED NUCLEAR IMPORT OF PICS%REACTOME%R-HSA-180910.2	Vpr-mediated nuclear import of PICs	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	AAAS	HMGA1	PSIP1	NUP160	NUP85	TPR	KPNA1	NUP88	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	NUP107	NUP153	NUP188	BANF1	
AQUAPORIN-MEDIATED TRANSPORT%REACTOME%R-HSA-445717.2	Aquaporin-mediated transport	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY5	GNG12	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	AQP9	AQP7	PRKAR2B	AQP8	AQP4	AQP2	AQP3	RAB11FIP2	MYO5B	AQP1	AQP6	AQP5	MIP	AQP10	AQP12A	AVP	AQP11	PRKACG	PRKACB	AVPR2	GNGT1	GNGT2	ADCY9	PRKAR1B	PRKAR1A	RAB11A	PRKACA	PRKAR2A	GNAS	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	ADCY4	ADCY3	
CONDENSATION OF PROPHASE CHROMOSOMES%REACTOME%R-HSA-2299718.1	Condensation of Prophase Chromosomes	SETD8	NCAPG2	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	MCPH1	CCNB1	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	PLK1	HIST3H3	NCAPD3	CDK1	RB1	SMC4	SMC2	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	SET	HIST1H3J	HIST1H3A	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	NCAPH2	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
SUMO IS TRANSFERRED FROM E1 TO E2 (UBE2I, UBC9)%REACTOME DATABASE ID RELEASE 74%3065678	SUMO is transferred from E1 to E2 (UBE2I, UBC9)	UBA2	SUMO1	UBE2I	SUMO3	SAE1	SUMO2	RWDD3	
SIGNALING BY EXTRACELLULAR DOMAIN MUTANTS OF KIT%REACTOME DATABASE ID RELEASE 74%9680187	Signaling by extracellular domain mutants of KIT	KIT	
ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA (PLCG)%REACTOME%R-HSA-9027277.1	Erythropoietin activates Phospholipase C gamma (PLCG)	EPOR	LYN	PLCG2	PLCG1	JAK2	EPO	IRS2	
ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS%REACTOME%R-HSA-2122948.2	Activated NOTCH1 Transmits Signal to the Nucleus	MIB2	MIB1	NCSTN	NEURL1	CNTN1	ITCH	DTX4	UBA52	NOTCH1	UBB	UBC	DNER	RPS27A	DTX1	DTX2	ARRB1	DLK1	ARRB2	PSEN2	ADAM10	DLL1	DLL4	APH1A	ADAM17	NEURL1B	APH1B	NUMB	JAG2	PSEN1	PSENEN	JAG1	
DEFECTIVE F8 ACCELERATES DISSOCIATION OF THE A2 DOMAIN%REACTOME%R-HSA-9672387.1	Defective F8 accelerates dissociation of the A2 domain	F8	
P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS%REACTOME%R-HSA-372708.1	p130Cas linkage to MAPK signaling for integrins	SRC	FGB	FGA	RAP1B	VWF	ITGA2B	RAP1A	FGG	TLN1	FN1	APBB1IP	PTK2	CRK	BCAR1	ITGB3	
TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA%REACTOME DATABASE ID RELEASE 74%159230	Transport of the SLBP Dependant Mature mRNA	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	AAAS	NUP160	NUP85	NCBP1	TPR	NCBP2	NUP88	EIF4E	NUP43	RAE1	SLBP	RANBP2	NUP155	NUP35	NUPL2	NUP37	NUP107	NUP153	NUP188	NXF1	
REGULATION OF FZD BY UBIQUITINATION%REACTOME DATABASE ID RELEASE 74%4641263	Regulation of FZD by ubiquitination	RPS27A	FZD5	WNT3A	FZD4	FZD6	LRP5	LRP6	FZD8	ZNRF3	USP8	UBA52	RSPO3	RSPO2	RSPO1	UBB	RSPO4	UBC	LGR6	LGR5	LGR4	RNF43	
ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN%REACTOME DATABASE ID RELEASE 74%1237044	Erythrocytes take up carbon dioxide and release oxygen	CA1	RHAG	HBB	HBA2	HBA1	CYB5R1	SLC4A1	AQP1	CYB5R2	CYB5R4	CA2	CA4	CYB5RL	
NUCLEAR ENVELOPE BREAKDOWN%REACTOME%R-HSA-2980766.2	Nuclear Envelope Breakdown	NUP214	NUP210	PRKCB	LMNB1	VRK1	PRKCA	NUP62	LEMD3	LEMD2	EMD	NUP93	NDC1	CTDNEP1	SEC13	NUP133	NUP50	CNEP1R1	NUP205	CCNB2	NUP54	POM121	CCNB1	AAAS	NUP160	NUP85	TPR	NUP88	NUP43	RAE1	RANBP2	NEK9	PLK1	NUP155	NUP35	NUPL2	NEK6	CDK1	LPIN1	NUP37	LPIN2	NEK7	LPIN3	NUP107	NUP153	NUP188	BANF1	
RNA POLYMERASE III CHAIN ELONGATION%REACTOME DATABASE ID RELEASE 74%73780	RNA Polymerase III Chain Elongation	POLR2E	POLR2F	POLR3GL	POLR2H	POLR3A	POLR3B	POLR2K	POLR3C	POLR2L	POLR3D	POLR3E	POLR1C	POLR3F	POLR3G	POLR3H	POLR3K	CRCP	
GALACTOSE CATABOLISM%REACTOME%R-HSA-70370.2	Galactose catabolism	PGM2L1	GALT	GALE	PGM2	GALK1	
SIGNALLING TO STAT3%REACTOME%R-HSA-198745.1	Signalling to STAT3	NGF	NTRK1	STAT3	
S PHASE%REACTOME%R-HSA-69242.2	S Phase	STAG1	STAG2	MCM7	MCM8	UBE2D1	CDC23	CDC26	WAPAL	CDC27	SKP2	ANAPC7	UBA52	UBE2E1	SMC1A	CCNA2	CCNA1	CCNE2	CCNE1	MCM3	CDC25B	MCM4	ANAPC4	CUL1	MCM5	ANAPC5	MCM6	ANAPC1	UBB	MCM2	ANAPC2	ANAPC15	ANAPC16	UBC	ANAPC10	ANAPC11	ORC5	ORC4	RPS27A	FZR1	ORC6	ORC1	MYC	ORC3	ORC2	CDT1	UBE2C	CDC6	UBE2S	RPA1	CDC16	RPA2	CDK2	PTK6	RPA3	PRIM2	PRIM1	ESCO1	ESCO2	POLA1	CABLES1	POLA2	WEE1	DNA2	RFC5	RFC3	FEN1	PCNA	RFC4	RFC1	LIG1	RFC2	POLE4	POLD3	POLD4	PSMD8	POLE2	POLD1	PSMD9	CDC45	PSMD6	GINS1	POLE3	PSMD7	POLD2	GINS2	PSMD4	POLE	GINS3	PSMD5	GINS4	PSMD2	PSMD3	PSMD1	E2F1	PSMA5	PSMA6	PSMA3	CDKN1A	PSMA4	CDKN1B	PSMA1	PSMA2	PSME3	PSME4	PSME1	CDC25A	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	LIN54	RBL2	LIN37	MAX	PSMB10	LIN9	PSMA7	E2F4	E2F5	LIN52	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	RB1	TFDP1	TFDP2	CKS1B	CCNH	AKT2	AKT3	RBBP4	AKT1	RBX1	GSK3B	CCND1	CDK4	SKP1	CDK7	SMC3	CDCA5	PDS5B	PDS5A	MNAT1	RAD21	
MITOCHONDRIAL UNCOUPLING%REACTOME%R-HSA-166187.3	Mitochondrial Uncoupling	SLC25A27	UCP3	UCP2	UCP1	SLC25A14	PM20D1	
FORMATION OF THE EARLY ELONGATION COMPLEX%REACTOME DATABASE ID RELEASE 74%113418	Formation of the Early Elongation Complex	NELFB	CTDP1	CCNH	SUPT4H1	POLR2A	POLR2B	POLR2C	NELFA	POLR2D	NELFCD	NCBP1	NCBP2	POLR2E	POLR2F	NELFE	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	SUPT5H	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	CDK7	ERCC3	ERCC2	MNAT1	
MITOCHONDRIAL ABC TRANSPORTERS%REACTOME%R-HSA-1369007.1	Mitochondrial ABC transporters	ABCB8	ABCB10	ABCB6	ABCB7	
SIGNALING BY TYPE 1 INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (IGF1R)%REACTOME%R-HSA-2404192.2	Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	IRS1	PTPN11	FGF20	FGF23	GAB2	FGF22	GAB1	FGF16	IGF1R	NRAS	PDPK1	SOS1	HRAS	FGF19	PIK3R2	FGF18	PIK3R1	FGFR4	PIK3CA	AKT2	TLR9	FGF10	FLT3	PDE3B	THEM4	TRIB3	KLB	FLT3LG	FRS2	IRS2	FGF1	PIK3CB	FGF2	IGF2	CILP	FGF3	IGF1	IRS4	PIK3R4	FGF4	FGF6	FGF7	FGF9	PIK3C3	
DISEASES OF DNA REPAIR%REACTOME%R-HSA-9675135.3	Diseases of DNA repair	MSH6	PMS2	MSH2	OGG1	NEIL1	NEIL3	MSH3	NTHL1	MLH1	
SARS-COV-1 GENOME REPLICATION AND TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%9679514	SARS-CoV-1 Genome Replication and Transcription	RB1	ZCRB1	GSK3A	DDX5	GSK3B	VHL	
TRNA PROCESSING IN THE MITOCHONDRION%REACTOME DATABASE ID RELEASE 74%6785470	tRNA processing in the mitochondrion	TRNT1	TRMT10C	ELAC2	KIAA0391	HSD17B10	
DISEASES OF MITOTIC CELL CYCLE%REACTOME DATABASE ID RELEASE 74%9675126	Diseases of mitotic cell cycle	CDKN1A	CDKN1B	E2F3	UBE2D1	CDC23	CDC26	CDC27	SKP2	ANAPC7	UBE2E1	CCND3	CCNE2	CCNE1	ANAPC4	CDKN1C	ANAPC5	ANAPC1	ANAPC2	ANAPC15	ANAPC16	E2F2	ANAPC10	ANAPC11	FZR1	CCND2	CDK6	UBE2C	UBE2S	CDC16	CDK2	CCND1	CDK4	RB1	TFDP1	TFDP2	E2F1	
DEFECTIVE SLC4A1 CAUSES HEREDITARY SPHEROCYTOSIS TYPE 4 (HSP4), DISTAL RENAL TUBULAR ACIDOSIS (DRTA) AND DRTA WITH HEMOLYTIC ANEMIA (DRTA-HA)%REACTOME DATABASE ID RELEASE 74%5619050	Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA)	SLC4A1	
DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS DUE TO P14ARF LOSS OF FUNCTION%REACTOME%R-HSA-9645722.2	Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function	C1QBP	CDKN2A	
BLOOD GROUP SYSTEMS BIOSYNTHESIS%REACTOME%R-HSA-9033658.2	Blood group systems biosynthesis	FUT2	FUT1	FUT3	ST6GALNAC6	FUT10	FUT11	ST3GAL4	B3GALT2	B3GALT1	FUT4	ST3GAL3	FUT6	FUT5	FUT7	FUT9	B3GALT4	B3GALT5	ST3GAL6	B4GALNT2	RHCE	RHD	
G1 PHASE%REACTOME%R-HSA-69236.4	G1 Phase	CDKN1A	CDKN1B	E2F3	CKS1B	PPP2R2A	ABL1	SKP2	PPP2R3B	UBA52	CCND3	RBL2	CCNE2	RBL1	CCNE1	E2F4	CUL1	E2F5	CDKN1C	LYN	CCNH	UBB	UBC	E2F2	CDKN2D	CDKN2B	CDKN2C	RPS27A	PPP2CA	CCND2	PPP2CB	CDK6	CDKN2A	PPP2R1A	CDK2	CCND1	CDK4	PTK6	RB1	SKP1	CDK7	TFDP1	JAK2	TFDP2	PPP2R1B	MNAT1	E2F1	
DEFECTIVE ABCD1 CAUSES ALD%REACTOME%R-HSA-5684045.2	Defective ABCD1 causes ALD	ABCD1	
SIGNALING BY WNT IN CANCER%REACTOME DATABASE ID RELEASE 74%4791275	Signaling by WNT in cancer	FZD5	WNT3A	FZD4	FZD6	LRP5	LRP6	CSNK1A1	FZD8	CTBP2	CTNNB1	PPP2CA	PORCN	PPP2CB	PPP2R1A	TNKS2	TNKS	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	DKK1	DKK2	PPP2R5C	DKK4	PPP2R1B	KREMEN1	AMER1	KREMEN2	AXIN1	APC	CTBP1	TCF7L2	RNF43	
INHIBITION OF MEMBRANE REPAIR%REACTOME%R-HSA-9635644.3	Inhibition of membrane repair	HGS	
DEFECTIVE RFT1 CAUSES RFT1-CDG (CDG-1N)%REACTOME%R-HSA-4570571.1	Defective RFT1 causes RFT1-CDG (CDG-1n)	RFT1	
IL-6-TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS%REACTOME%R-HSA-6788467.3	IL-6-type cytokine receptor ligand interactions	IL6ST	JAK1	IL11	CNTFR	CNTF	TYK2	OSMR	IL31RA	IL31	CTF1	OSM	JAK2	LIFR	IL11RA	LIF	CLCF1	CRLF1	
VITAMINS B6 ACTIVATION TO PYRIDOXAL PHOSPHATE%REACTOME%R-HSA-964975.1	Vitamins B6 activation to pyridoxal phosphate	PDXK	PNPO	AOX1	
FOXO-MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS, METABOLIC AND NEURONAL GENES%REACTOME%R-HSA-9615017.1	FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	NR3C1	FOXO1	FBXO32	IGFBP1	INS	PLXNA4	SMAD4	PPARGC1A	SMAD2	SREBF1	SMAD3	SOD2	TRIM63	ABCA6	G6PC	SIRT3	POMC	FOXO3	PCK1	SIN3A	CAT	RETN	GCK	NPY	FOXO6	FOXO4	ATXN3	HDAC2	HDAC1	AGRP	
DEFECTIVE SLC5A2 CAUSES RENAL GLUCOSURIA (GLYS1)%REACTOME DATABASE ID RELEASE 74%5658208	Defective SLC5A2 causes renal glucosuria (GLYS1)	SLC5A2	
TRANSLATION INITIATION COMPLEX FORMATION%REACTOME%R-HSA-72649.3	Translation initiation complex formation	RPS26	RPS25	RPS28	RPS27	RPS29	RPS20	RPS21	RPS24	RPS23	RPS4X	RPS3A	PABPC1	RPS27L	RPS15A	EIF2S2	RPS3	EIF2S1	EIF4H	RPS27A	EIF2S3	RPS2	EIF4E	EIF4B	EIF3M	EIF3K	EIF3L	EIF3I	EIF3J	EIF4G1	EIF3G	EIF3H	EIF3E	EIF3F	FAU	EIF3C	EIF3D	EIF3A	EIF3B	EIF4A2	EIF4A1	RPS15	RPS14	RPS17	RPS16	RPS19	RPS18	RPS11	RPS10	RPS13	RPS12	RPS9	RPS7	EIF1AX	RPS8	RPS5	RPS6	RPSA	RPS4Y2	RPS4Y1	
NCAM1 INTERACTIONS%REACTOME DATABASE ID RELEASE 74%419037	NCAM1 interactions	CACNB2	CACNB3	CACNB4	AGRN	NCAM1	COL4A2	COL9A1	COL4A1	COL9A3	GFRA1	COL6A2	COL9A2	COL4A4	PSPN	COL4A3	GFRA2	COL6A1	GFRA4	GDNF	COL6A3	COL4A5	COL6A6	COL6A5	CACNA1D	CACNA1C	NCAN	CACNA1H	CACNA1G	CACNA1I	CACNA1S	PRNP	ST8SIA4	CNTN2	NRTN	ST8SIA2	ARTN	CACNB1	
NGF PROCESSING%REACTOME%R-HSA-167060.1	NGF processing	PCSK5	NGF	FURIN	PCSK6	
DEFECTIVE CYP4F22 CAUSES ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 5 (ARCI5)%REACTOME%R-HSA-5579005.2	Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)	CYP4F22	
PLATELET DEGRANULATION%REACTOME%R-HSA-114608.3	Platelet degranulation	TUBA4A	TF	SPARC	ABCC4	ITGA2B	APOA1	RAB27B	HGF	VCL	LEFTY2	ALDOA	FLNA	PPIA	HSPA5	CD9	CD109	ITGB3	CFL1	BRPF3	A2M	EGF	FAM49B	ISLR	LAMP2	HABP4	FAM3C	CHID1	APLP2	ACTN1	SERPINF2	ACTN4	GTPBP2	SYTL4	SEPP1	TIMP1	TMX3	TAGLN2	FIGF	SCG3	NHLRC2	TEX264	VEGFB	STXBP2	ENDOD1	VEGFC	A1BG	CYB5R1	VEGFA	APOH	PSAP	VTI1B	TGFB2	SERPINA1	TGFB3	RARRES2	IGF2	IGF1	PPBP	MANF	SELP	SCCPDH	CALU	MAGED2	CAP1	HRG	FERMT3	LGALS3BP	CLU	SERPINA3	ORM1	PLG	ECM1	WDR1	APOOL	PLEK	OLA1	SOD1	CTSW	ORM2	SERPINA4	TMSB4X	PHACTR2	TIMP3	QSOX1	CFD	SRGN	AHSG	ANXA5	MMRN1	TOR4A	CD63	ITIH4	ITIH3	THBS1	TTN	CLEC3B	ALB	CDC37L1	SPP2	TGFB1	LY6G6F	PCDH7	LHFPL2	PCYOX1L	FN1	GAS6	APP	PROS1	F13A1	KNG1	PFN1	FGB	FGA	ACTN2	VWF	TLN1	FGG	SERPINE1	PDGFB	F5	F8	SERPING1	CD36	PF4	
DEFECTIVE B4GALT1 CAUSES B4GALT1-CDG (CDG-2D)%REACTOME%R-HSA-3656244.2	Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	LUM	OGN	OMD	PRELP	KERA	FMOD	B4GALT1	
METABOLISM OF WATER-SOLUBLE VITAMINS AND COFACTORS%REACTOME DATABASE ID RELEASE 74%196849	Metabolism of water-soluble vitamins and cofactors	SLC5A8	MMAB	SHMT1	ABCC1	PTGS2	BTD	HLCS	TCN2	CD320	PRSS1	SLC23A2	CYB5A	CYB5R3	GSTO2	SLC23A1	ACACA	GIF	PTGIS	PCCA	PCCB	PC	MCCC2	CTRB2	MCCC1	CTRB1	BST1	VNN1	VNN2	CYP8B1	FOLR2	MTRR	NNMT	GSTO1	MTR	ABCD4	SLC2A1	CUBN	AMN	PANK4	ALDH1L1	PANK2	PANK3	PANK1	NADSYN1	ALDH1L2	FLAD1	ENPP2	ENPP1	NT5E	ENPP3	PRSS3	MTHFD1	PDZD11	MTHFD2	SLC2A3	MTHFD2L	SHMT2	ACACB	LMBRD1	PPCS	PNPO	SLC19A3	NADK	SLC5A6	SLC19A1	MMACHC	MMADHC	SLC19A2	SLC52A2	SLC52A3	SLC52A1	MTHFR	MTHFS	PARP16	PARP14	PARP10	DHFR	PARP6	PARP4	TCN1	PARP9	MMAA	FASN	MUT	PARP8	CTRC	MOCS2	MOCS3	QPRT	GPHN	PPCDC	THTPA	NADK2	CARKD	DHFRL1	RNLS	APOA1BP	NMRK2	SLC22A13	RFK	SLC46A1	NAPRT	NMRK1	NAMPT	ACP5	NUDT12	AOX1	CD38	COASY	SLC25A16	SLC25A19	PDXK	MTHFD1L	AASDHPPT	TPK1	MOCOS	NMNAT3	NMNAT2	NMNAT1	SLC25A32	
NIK-->NONCANONICAL NF-KB SIGNALING%REACTOME%R-HSA-5676590.1	NIK-->noncanonical NF-kB signaling	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	CUL1	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	UBA3	UBE2M	MAP3K14	BTRC	PSMD8	SKP1	NFKB2	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	FBXW11	PSMD2	PSMD3	PSMD1	RELB	CHUK	PSMA5	
DEFECTIVE SLC24A4 CAUSES HYPOMINERALIZED AMELOGENESIS IMPERFECTA (AI)%REACTOME DATABASE ID RELEASE 74%5619055	Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI)	SLC24A4	
CLASS I MHC MEDIATED ANTIGEN PROCESSING & PRESENTATION%REACTOME%R-HSA-983169.3	Class I MHC mediated antigen processing & presentation	RNF19B	RNF19A	TIRAP	SEC23A	UBE2D1	TAP2	CDC23	TLR1	CDC26	TAP1	CDC27	SEC13	SKP2	FBXO4	UBA52	ANAPC7	FBXO6	UBE2E1	TRAIP	SEC24B	SEC24A	TLR6	FBXW4	FBXW5	FBXW10	FBXW7	ANAPC4	CUL1	BTBD1	TLR2	ANAPC5	FBXW9	ANAPC1	UBB	FBXW2	GLMN	ANAPC2	BTBD6	SEC24D	SEC24C	UBC	RNF182	ANAPC10	ANAPC11	RNF14	RPS27A	FZR1	DTX3L	TRAF7	RBBP6	RNF25	UBE2C	FBXL3	UBE2S	CDC16	UBAC1	RNF213	TRIP12	KCTD7	UBA3	HSPA5	RNF41	UBE2L3	SEC22B	UBE2V2	CDC20	RNF217	VAMP3	UBE2J2	DZIP3	RNF220	UBE2B	UBE2A	FBXO27	LTN1	FBXO21	ITGAV	FBXO22	FBXW8	FBXO17	PSMD8	FBXO15	IKBKB	FBXO10	PSMD9	FBXO11	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	FBXO44	PSMD3	FBXO41	PSMD1	FBXO40	IKBKG	FBXO30	FBXO31	CHUK	PSMA5	PSMA6	PSMA3	TRIM71	HERC2	PSMA4	PSMA1	TRIM69	PSMA2	UNKL	PSME3	UBE2D2	PSME4	FBXO32	PSME1	PSME2	CDC34	PSMD10	TRIM50	PSMB11	CUL7	PSMD12	MGRN1	PSMD11	RCHY1	PSMD14	ZNRF1	UBE2V1	PSMD13	ZNRF2	PSMB10	TRIM41	PSMA7	TRIM39	RNF34	TRIM36	PSMA8	TRIM63	TRIM37	SEC31A	PSMB6	TRIM32	HERC4	PSMB7	UBE2N	HERC3	PSMB4	HERC1	PSMB5	FBXO7	PSMB2	HERC6	PSMB3	FBXO9	PSMB1	PSMF1	FBXO2	SHFM1	PSMB8	PSMB9	TRIM11	PSMC5	PSMC6	PSMC3	PSMC4	FBXL8	PSMC1	CD207	PSMC2	FBXL4	HLA-A	FBXL7	B2M	SH3RF1	CUL5	RNF144B	GAN	KLHL2	KLHL3	KLHL9	KLHL5	UBE3C	VHL	UBE3D	BTK	UBE3A	UBE3B	UBE2Z	LY96	FBXW12	UBE4A	UBA6	UBA5	UBE2F	CD14	UBE2H	TLR4	UBE2W	SOCS3	UBE2U	UBE2O	UBA1	UBE2K	NCF1	UFL1	NCF2	TAPBP	NCF4	ASB13	ASB14	RNF6	ASB11	RNF7	ASB12	CYBB	RNF4	ASB17	ASB18	ASB15	RBX1	ASB16	ASB10	SEC61G	SEC61B	HECW2	ANAPC13	MEX3C	NEDD4	NPEPPS	RNF111	MKRN1	UBR4	UBR2	UBR1	MIB2	UBOX5	TPP2	ITGB5	KBTBD13	FBXL22	ITCH	FBXL20	HECTD1	HECTD2	HECTD3	FBXL19	FBXL18	FBXL15	FBXL16	FBXL13	FBXL14	FBXL12	CBLB	FBXL5	TCEB2	DET1	TCEB1	GPR75-ASB3	UBE2L6	KBTBD6	KBTBD7	KBTBD8	HERC5	LMO7	TRIM21	LONRF1	BLMH	WWP1	HLA-B	HLA-C	THOP1	HLA-F	HLA-G	HLA-E	PARK2	HACE1	CUL3	LRSAM1	LRRC41	UBA7	SPSB2	SPSB1	NEDD4L	SPSB4	UBE2D4	SMURF2	SMURF1	AREL1	UBE2E3	ATG7	UBE2E2	STUB1	UBE2M	ZBTB16	ZNF645	ERAP2	FCGR1B	ERAP1	LRR1	CCNF	KEAP1	UBE2J1	CUL2	ARIH2	CTSV	CTSS	CTSL	LNPEP	PDIA3	HUWE1	CALR	MYLIP	UBE2G1	UBE2G2	FCGR1A	CANX	KLHL41	SAR1B	VAMP8	KCTD6	KLHL42	KLHL11	KLHL13	KLHL25	KLHL21	KLHL22	KLHL20	STX4	SEC61A2	SEC61A1	UBE2Q1	UBE2Q2	CYBA	PJA2	PJA1	UBE2R2	VPRBP	ASB8	ASB9	LNX1	ASB6	ASB7	ASB4	ASB5	UBE2D3	ASB2	ASB1	RNF115	RNF114	WSB1	RNF123	RNF126	BTRC	SOCS1	MRC2	TRIM9	TRIM4	MRC1	SKP1	MYD88	SIAH2	RNF138	FBXW11	SIAH1	SNAP23	RNF130	CD36	RLIM	RBCK1	
ACTIVATION OF GABAB RECEPTORS%REACTOME%R-HSA-991365.3	Activation of GABAB receptors	ADCY2	KCNJ5	ADCY1	KCNJ6	ADCY8	GABBR1	ADCY7	KCNJ10	ADCY6	KCNJ12	ADCY5	KCNJ9	KCNJ15	GNG12	KCNJ16	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNAL	GNB5	GNAT3	GNGT1	GNGT2	ADCY9	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	GNAI3	KCNJ2	ADCY4	KCNJ3	GNAI1	KCNJ4	ADCY3	GNAI2	GABBR2	
ESTROGEN-DEPENDENT GENE EXPRESSION%REACTOME DATABASE ID RELEASE 74%9018519	Estrogen-dependent gene expression	STAG1	STAG2	HIST2H2AC	FOS	H2AFJ	GATA3	FOSB	TLE3	TNRC6C	MOV10	AGO3	H2AFZ	AGO4	H2AFX	H2AFV	SMC1A	AGO1	HIST2H2BE	AGO2	HIST4H4	NRIP1	TNRC6A	TNRC6B	HIST1H2BN	CCNT1	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	CARM1	HIST1H2BL	HIST1H2BK	HIST2H4A	MYC	HIST2H4B	GPAM	GREB1	CDK9	NR5A2	TFF1	MED1	KANK1	ZNF217	EBAG9	FOXA1	CHD1	CXXC5	USF2	USF1	HDAC1	CITED1	YY1	PGR	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	BCL2	POLR2F	POLR2G	CXCL12	POLR2H	POLR2I	DDX5	POLR2J	HSP90AB1	POLR2K	POLR2L	GTF2A1	GTF2A2	AXIN1	CBFB	SP1	KDM4B	PRMT1	KPNA2	POU2F1	CTSD	TBP	GTF2F1	GTF2F2	NCOA1	NCOA2	KCTD6	ESR1	HIST1H2AE	NCOA3	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	FKBP4	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	PTGES3	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	ATF2	HIST1H3A	RUNX1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	CCND1	H3F3B	HIST1H4K	HIST1H4L	JUN	KAT2B	TGFA	H3F3A	KDM1A	SMC3	H2BFS	HSP90AA1	JUND	HIST1H4A	HIST1H4B	HIST1H4H	MYB	HIST1H4I	CREBBP	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	RAD21	HIST2H2AA4	
FGFR3 LIGAND BINDING AND ACTIVATION%REACTOME DATABASE ID RELEASE 74%190239	FGFR3 ligand binding and activation	FGF4	FGF16	FGF9	FGF18	GALNT3	FGF20	FGF1	FGF23	FGF2	
VARIANT SLC6A20 CONTRIBUTES TOWARDS HYPERGLYCINURIA (HG) AND IMINOGLYCINURIA (IG)%REACTOME DATABASE ID RELEASE 74%5660686	Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	SLC6A20	
DEFECTIVE DPAGT1 CAUSES DPAGT1-CDG (CDG-1J) AND CMSTA2%REACTOME DATABASE ID RELEASE 74%4549356	Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2	DPAGT1	
DISEASES OF CARBOHYDRATE METABOLISM%REACTOME%R-HSA-5663084.3	Diseases of carbohydrate metabolism	ALDOB	GYS2	GLB1	KHK	UBA52	GAA	TALDO1	UBB	PPP1R3C	GYG2	NHLRC1	GYG1	UBC	G6PC	GBE1	RPS27A	EPM2A	NAGLU	IDUA	G6PC3	HGSNAT	DCXR	HYAL1	GALNS	IDS	ARSB	RPIA	GYS1	GNS	SI	SGSH	LCT	GUSB	
HCMV LATE EVENTS%REACTOME%R-HSA-9610379.2	HCMV Late Events	VPS37C	VPS37D	VPS37A	VPS37B	HIST2H2AC	SNF8	NUP62	CHMP2B	CHMP2A	CHMP4C	NDC1	CHMP4B	SEC13	NUP133	UBAP1	CHMP3	CHMP4A	CHMP6	CHMP7	HIST2H2BE	VPS25	VPS28	HIST4H4	NUP50	NUP54	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H2AB	HIST2H4B	HIST1H2AG	HIST1H2AA	NUP43	HIST1H2AM	RAE1	HIST1H2AL	RANBP2	HIST1H2AI	HIST1H2AH	HIST1H2AK	NUP35	HIST2H2BF	HIST3H2A	NUPL2	NUP37	HNRNPK	CHMP1A	NUP107	NUP188	HIST1H2AE	HIST1H2AD	HIST3H2BB	CEBPD	HIST1H2AC	HIST1H2AB	NUP214	NUP210	HIST1H2AJ	NUP93	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	NUP205	POM121	HIST1H3J	AAAS	NUP160	HIST1H3A	NUP85	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	NUP155	HIST1H4K	HIST1H4L	NUP153	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	TSG101	HIST1H4J	HIST1H4C	HIST1H4D	VPS4A	HIST1H4E	MVB12B	HIST1H4F	MVB12A	VPS36	HIST2H2AA3	HIST2H2AA4	
EML4 AND NUDC IN MITOTIC SPINDLE FORMATION%REACTOME%R-HSA-9648025.2	EML4 and NUDC in mitotic spindle formation	RCC2	DYNLL1	DYNC1LI1	NDC80	ZWINT	CKAP5	DYNC1LI2	AHCTF1	SGOL2	ZW10	SGOL1	RPS27	NUF2	MAPRE1	SPDL1	SEC13	NDEL1	NUP133	NUDC	RANGAP1	PAFAH1B1	INCENP	BIRC5	DYNC1I2	ITGB3BP	MIS12	CENPA	XPO1	AURKB	NSL1	CENPC	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	PPP2CA	KIF18A	CENPN	CLASP1	CENPO	PPP2CB	B9D2	CENPP	DYNC1H1	CENPQ	NUP43	SPC24	SPC25	RANBP2	NDE1	PLK1	CLIP1	NUP37	PPP1CC	NUP107	PPP2R1B	DYNLL2	KIF2A	KIF2C	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	NUP160	NUP85	PPP2R1A	CLASP2	NEK9	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	NEK6	ERCC6L	PPP2R5C	NEK7	ZWILCH	CASC5	KNTC1	MAD1L1	CDCA8	DYNC1I1	EML4	PMF1	SKA1	SKA2	DSN1	CENPE	
L13A-MEDIATED TRANSLATIONAL SILENCING OF CERULOPLASMIN EXPRESSION%REACTOME%R-HSA-156827.3	L13a-mediated translational silencing of Ceruloplasmin expression	UBA52	EIF2S2	EIF2S1	EIF2S3	RPS27A	RPL4	EIF4A2	EIF4A1	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	EIF1AX	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	PABPC1	RPS27L	RPS15A	RPL14	RPS3	EIF4H	RPL13	RPL15	RPS2	RPL18	RPL17	EIF4E	EIF4B	RPL19	RPL35A	RPL23A	EIF3M	EIF3K	EIF3L	EIF3I	EIF4G1	EIF3J	EIF3G	EIF3H	EIF3E	RPL22L1	EIF3F	FAU	EIF3C	EIF3D	EIF3A	RPL26L1	EIF3B	
HSP90 CHAPERONE CYCLE FOR SHRS%REACTOME DATABASE ID RELEASE 74%3371497	HSP90 chaperone cycle for SHRs	CAPZA3	FKBP4	DYNLL1	DYNC1LI1	CAPZA1	DYNC1LI2	CAPZA2	DYNLL2	NR3C1	DNAJB1	ACTR10	PGR	DYNC1I2	HSPA1L	DCTN2	STIP1	DCTN3	PTGES3	HSPA2	FKBP5	DCTN6	DCTN5	DNAJA1	DNAJA4	DCTN1	DNAJA2	DCTN4	ACTR1A	DYNC1H1	HSP90AB1	HSPA8	NR3C2	CAPZB	AR	HSP90AA1	DYNC1I1	
DEFECTIVE LFNG CAUSES SCDO3%REACTOME DATABASE ID RELEASE 74%5083630	Defective LFNG causes SCDO3	NOTCH3	LFNG	NOTCH4	NOTCH2	NOTCH1	
SUMOYLATION OF TRANSCRIPTION COFACTORS%REACTOME DATABASE ID RELEASE 74%3899300	SUMOylation of transcription cofactors	PHC2	PHC1	MKL1	DAXX	TOPORS	PHC3	BMI1	PPARGC1A	DDX17	PIAS1	SUMO3	SUMO2	NRIP1	ZNF131	PIAS4	NPM1	PIAS3	ING2	RING1	NCOR2	ZNF350	MBD1	DDX5	HIPK2	SIN3A	PCGF2	RNF2	SAFB	UHRF2	TRIM28	SUMO1	NCOA1	UBE2I	NCOA2	PARK7	CBX8	CREBBP	EP300	CBX4	CTBP1	CBX2	
DEFECTIVE SLC35A1 CAUSES CONGENITAL DISORDER OF GLYCOSYLATION 2F (CDG2F)%REACTOME%R-HSA-5663020.1	Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F)	SLC35A1	
RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS%REACTOME DATABASE ID RELEASE 74%5666185	RHO GTPases Activate Rhotekin and Rhophilins	ROPN1	TAX1BP3	LIN7B	RTKN	RHPN1	RHOC	RHPN2	RHOA	RHOB	
CGMP EFFECTS%REACTOME DATABASE ID RELEASE 74%418457	cGMP effects	PDE10A	KCNMB1	KCNMB2	PRKG2	KCNMB3	KCNMB4	PDE5A	MRVI1	PDE9A	ITPR1	PDE11A	PDE2A	PDE1B	PDE1A	KCNMA1	
ADRENALINE,NORADRENALINE INHIBITS INSULIN SECRETION%REACTOME%R-HSA-400042.1	Adrenaline,noradrenaline inhibits insulin secretion	CACNB2	CACNB3	ADCY6	ADCY5	GNG12	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	GNGT1	GNGT2	CACNA1D	CACNA1C	CACNA2D2	GNG3	GNG10	ADRA2C	GNG2	GNG5	ADRA2A	GNG4	GNG7	GNG8	GNAI1	GNAI2	
RPIA DEFICIENCY: FAILED CONVERSION OF R5P TO RU5P%REACTOME%R-HSA-5659996.2	RPIA deficiency: failed conversion of R5P to RU5P	RPIA	
SIGNALING BY FGFR3 IN DISEASE%REACTOME DATABASE ID RELEASE 74%5655332	Signaling by FGFR3 in disease	FRS2	FGF20	FGF1	FGF23	FGF2	GAB1	FGF4	FGFR3	FGF16	NRAS	FGF9	PLCG1	SOS1	HRAS	FGF18	PIK3R1	PIK3CA	
REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA-CARBOXYLATED PROTEINS%REACTOME%R-HSA-159782.3	Removal of aminoterminal propeptides from gamma-carboxylated proteins	F2	F7	BGLAP	F10	PROZ	F9	GAS6	PROC	FURIN	PROS1	
POLB-DEPENDENT LONG PATCH BASE EXCISION REPAIR%REACTOME%R-HSA-110362.2	POLB-Dependent Long Patch Base Excision Repair	POLB	APEX1	FEN1	PARP2	LIG1	PARG	PARP1	ADPRHL2	
SIGNALING BY LEPTIN%REACTOME DATABASE ID RELEASE 74%2586552	Signaling by Leptin	IRS1	PTPN11	JAK2	STAT5A	STAT5B	IRS2	SOCS3	LEP	STAT3	
DEFECTIVE SLC17A8 CAUSES AUTOSOMAL DOMINANT DEAFNESS 25 (DFNA25)%REACTOME%R-HSA-5619076.1	Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25)	SLC17A8	
TRANSLESION SYNTHESIS BY POLK%REACTOME%R-HSA-5655862.1	Translesion synthesis by POLK	RPS27A	POLK	REV1	RFC5	MAD2L2	RFC3	REV3L	PCNA	RPA1	RFC4	RPA2	RFC1	UBA52	RFC2	RPA3	UBB	UBC	
CONSTITUTIVE SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS%REACTOME%R-HSA-2644606.1	Constitutive Signaling by NOTCH1 PEST Domain Mutants	MIB2	MIB1	CCNC	NCSTN	NEURL1	MAML3	MAMLD1	HDAC4	UBA52	HDAC5	NOTCH1	HDAC8	HDAC9	HDAC7	CDK8	HEY1	HEY2	CUL1	UBB	UBC	HDAC10	HDAC11	RPS27A	TBL1X	MYC	SNW1	HDAC2	HDAC1	HDAC3	TBL1XR1	HDAC6	NCOR2	NCOR1	RBX1	MAML2	MAML1	KAT2B	SKP1	PSEN2	RBPJ	ADAM10	KAT2A	DLL1	HEYL	DLL4	ADAM17	APH1A	NEURL1B	APH1B	CREBBP	EP300	HES1	HES5	JAG2	PSENEN	PSEN1	JAG1	
SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS%REACTOME%R-HSA-1839117.2	Signaling by cytosolic FGFR1 fusion mutants	ZMYM2	FGFR1OP2	TRIM24	STAT5A	MYO18A	STAT5B	LRRFIP1	BCR	CPSF6	GAB2	CUX1	STAT1	STAT3	FGFR1OP	PIK3R1	PIK3CA	
LEADING STRAND SYNTHESIS%REACTOME DATABASE ID RELEASE 74%69109	Leading Strand Synthesis	POLA2	RFC5	RFC3	PCNA	RFC4	RFC1	RFC2	POLD3	POLD4	POLD1	POLD2	PRIM2	PRIM1	POLA1	
SULFIDE OXIDATION TO SULFATE%REACTOME%R-HSA-1614517.2	Sulfide oxidation to sulfate	TSTD1	SQRDL	ETHE1	SUOX	TST	SLC25A10	
PEROXISOMAL PROTEIN IMPORT%REACTOME%R-HSA-9033241.3	Peroxisomal protein import	DDO	UBE2D2	UBE2D1	PECR	PHYH	HACL1	SLC27A2	UBA52	NUDT7	ACOT8	EHHADH	CRAT	HSD17B4	DECR2	ACAA1	ACOT4	UBB	UBC	RPS27A	USP9X	IDH1	SCP2	ZFAND6	PEX26	NUDT19	LONP2	MPV17	GSTK1	ECH1	PIPOX	GNPAT	ACOT2	PEX2	HAO1	HAO2	NOS2	TYSND1	UBE2D3	DAO	AMACR	PEX10	PEX12	IDE	PEX13	CROT	PEX14	CAT	PEX1	HMGCL	BAAT	PEX7	EPHX2	ACOX2	ACOX1	PEX6	AGPS	ACOX3	DHRS4	AGXT	PAOX	
RNA POLYMERASE II PROMOTER ESCAPE%REACTOME DATABASE ID RELEASE 74%73776	RNA Polymerase II Promoter Escape	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	CCNH	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	TBP	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	GTF2A1	CDK7	GTF2A2	GTF2B	ERCC3	TAF9	TAF1L	AK6	ERCC2	GTF2E1	GTF2E2	TAF7L	MNAT1	TAF9B	TAF15	TAF12	TAF13	TAF10	
MPS IV - MORQUIO SYNDROME A%REACTOME DATABASE ID RELEASE 74%2206290	MPS IV - Morquio syndrome A	GALNS	
MET ACTIVATES STAT3%REACTOME%R-HSA-8875791.1	MET activates STAT3	HGF	MET	STAT3	
TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN%REACTOME%R-HSA-6804115.1	TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	CNOT2	CNOT3	PLK2	RQCD1	CNOT8	BTG2	TNKS1BP1	CNOT6L	CENPJ	CDC25C	CNOT6	PLAGL1	PLK3	NPM1	CNOT10	CNOT4	CNOT7	RGCC	CNOT1	CNOT11	TP53	
BIOTIN TRANSPORT AND METABOLISM%REACTOME DATABASE ID RELEASE 74%196780	Biotin transport and metabolism	MCCC1	ACACA	PDZD11	BTD	PCCA	PCCB	ACACB	HLCS	PC	MCCC2	SLC5A6	
DERMATAN SULFATE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%2022923	Dermatan sulfate biosynthesis	CHST14	BCAN	NCAN	UST	BGN	VCAN	DCN	DSE	CSPG5	CSPG4	DSEL	
CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE%REACTOME DATABASE ID RELEASE 74%442720	CREB1 phosphorylation through the activation of Adenylate Cyclase	ADCY1	ADCY8	CREB1	PRKAR1B	PRKAR1A	PRKX	PRKAR2B	PRKAR2A	PRKACA	PRKACG	PRKACB	
SUNITINIB-RESISTANT PDGFR MUTANTS%REACTOME%R-HSA-9674401.1	Sunitinib-resistant PDGFR mutants	PDGFRA	
HUR (ELAVL1) BINDS AND STABILIZES MRNA%REACTOME%R-HSA-450520.2	HuR (ELAVL1) binds and stabilizes mRNA	NUP214	ELAVL1	XPO1	PRKCA	PRKCD	SET	TNFSF13	ANP32A	
SUMOYLATION OF SUMOYLATION PROTEINS%REACTOME DATABASE ID RELEASE 74%4085377	SUMOylation of SUMOylation proteins	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	TOPORS	NUP50	NUP205	SUMO2	NUP54	POM121	PIAS4	AAAS	NUP160	NUP85	TPR	NUP88	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	NUP107	SUMO1	NUP153	NUP188	UBE2I	
METAL ION SLC TRANSPORTERS%REACTOME%R-HSA-425410.2	Metal ion SLC transporters	SLC31A1	SLC30A3	SLC30A7	SLC30A2	SLC30A6	SLC30A8	SLC30A1	SLC41A2	SLC30A5	SLC41A1	SLC30A10	CP	SLC39A10	SLC39A4	SLC11A1	SLC39A14	SLC39A6	SLC39A5	SLC39A8	SLC39A7	SLC39A2	SLC39A1	SLC39A3	SLC40A1	HEPH	SLC11A2	
TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3:SMAD4 HETEROTRIMER%REACTOME DATABASE ID RELEASE 74%2173793	Transcriptional activity of SMAD2 SMAD3:SMAD4 heterotrimer	CCNK	CCNC	UBE2D1	SP1	UBA52	NEDD4L	SMAD4	SMAD2	SMURF2	SMAD3	CDK8	RBL1	E2F4	E2F5	SMAD7	UBB	CCNT1	UBE2D3	UBC	NCOR2	PPM1A	NCOR1	CDKN2B	RPS27A	MYC	CDK9	TGIF1	WWTR1	SKIL	TGIF2	CCNT2	TRIM33	PARP1	SNW1	SERPINE1	MEN1	JUNB	USP9X	RNF111	TFDP1	HDAC1	ATP1B4	TFDP2	SKI	
ARMS-MEDIATED ACTIVATION%REACTOME DATABASE ID RELEASE 74%170984	ARMS-mediated activation	YWHAB	KIDINS220	NGF	NTRK1	BRAF	RAP1A	CRK	
TRANSCRIPTIONAL REGULATION BY E2F6%REACTOME DATABASE ID RELEASE 74%8953750	Transcriptional Regulation by E2F6	L3MBTL2	EHMT1	PHC1	CHEK1	CBX3	CDC7	PHC3	BMI1	CBX5	MAX	YAF2	EZH2	EHMT2	RING1	BRCA1	RBBP4	E2F6	MGA	SUZ12	RBBP7	RBBP8	PCGF2	RNF2	UXT	PCGF6	RRM2	RAD51	RYBP	EPC1	APAF1	TFDP1	TFDP2	E2F1	EED	
ERKS ARE INACTIVATED%REACTOME DATABASE ID RELEASE 74%202670	ERKs are inactivated	MAPK3	PPP2CA	PPP2CB	VRK3	MAPK1	DUSP4	PPP2R1A	PPP2R5D	DUSP6	DUSP7	PPP2R1B	DUSP3	MAPK7	
CYTOSOLIC IRON-SULFUR CLUSTER ASSEMBLY%REACTOME DATABASE ID RELEASE 74%2564830	Cytosolic iron-sulfur cluster assembly	NARFL	NUBP1	CIAO1	NUBP2	NDOR1	FAM96B	MMS19	CIAPIN1	ABCB7	POLD1	BRIP1	ERCC2	RTEL1	
ACTIVATION OF BMF AND TRANSLOCATION TO MITOCHONDRIA%REACTOME%R-HSA-139910.2	Activation of BMF and translocation to mitochondria	DYNLL2	BMF	MAPK8	
DEFECTIVE ALG3 CAUSES ALG3-CDG (CDG-1D)%REACTOME%R-HSA-4720475.1	Defective ALG3 causes ALG3-CDG (CDG-1d)	ALG3	
COMPLEX I BIOGENESIS%REACTOME DATABASE ID RELEASE 74%6799198	Complex I biogenesis	NDUFS8	NDUFS7	NDUFS6	NDUFS5	NDUFS4	NDUFS3	NDUFS2	NDUFS1	NDUFB9	NDUFB8	NDUFB7	NDUFB6	NDUFB5	NDUFB4	NDUFB3	NDUFB2	NDUFB1	NDUFA9	NDUFA8	NDUFA7	TIMMDC1	NDUFA6	NDUFA5	NUBPL	NDUFA3	NDUFA2	NDUFA1	NDUFAB1	MT-ND6	NDUFA13	MT-ND4	MT-ND5	NDUFA11	NDUFA12	NDUFA10	MT-ND2	MT-ND3	MT-ND1	TMEM126B	NDUFB10	NDUFB11	NDUFV3	NDUFV2	NDUFV1	NDUFAF6	NDUFAF7	NDUFAF4	NDUFAF5	NDUFAF2	NDUFAF3	NDUFAF1	ECSIT	ACAD9	NDUFC2	NDUFC1	
O-GLYCOSYLATION OF TSR DOMAIN-CONTAINING PROTEINS%REACTOME DATABASE ID RELEASE 74%5173214	O-glycosylation of TSR domain-containing proteins	ADAMTS16	ADAMTS18	SPON2	THBS1	SEMA5B	SPON1	THSD7B	POFUT2	ADAMTSL1	ADAMTS4	ADAMTS5	ADAMTSL4	ADAMTSL3	ADAMTSL2	ADAMTS1	THSD7A	ADAMTS6	ADAMTS2	ADAMTS7	ADAMTS3	SBSPON	ADAMTS20	B3GLCT	THBS2	CFP	ADAMTS8	ADAMTS12	THSD1	ADAMTS9	ADAMTS10	ADAMTS14	THSD4	ADAMTS15	ADAMTS13	ADAMTS19	ADAMTS17	SEMA5A	
AXON GUIDANCE%REACTOME DATABASE ID RELEASE 74%422475	Axon guidance	SH3KBP1	ROBO1	UBA52	UBB	UBC	CXCR4	AKAP5	RPS27A	CLASP1	PIK3CD	IRS2	PIK3CB	CDK5R1	ARHGAP39	ARHGAP35	NRCAM	DSCAM	EFNA5	EFNA4	RPL4	EFNB2	SDCBP	EFNB1	RPL5	EFNB3	RPL30	RPL3	EFNA1	RPL32	EFNA3	RPL31	RPL34	EFNA2	RPL10L	FES	RPL8	RPL10A	RPL9	RPL6	USP33	RPL7	RPS15	RPS14	RPS17	DCC	RPS16	GAP43	RPL18A	RPS19	DCX	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	CLASP2	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	PABPC1	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	HSPA8	MAPK14	MAPK11	ARPC1B	EIF4G1	ARPC1A	RPL22L1	WASL	ACTB	FAU	ACTG1	NCK1	ACTR3	VAV3	ACTR2	RPL26L1	VAV2	CSNK2A1	SRC	MYO10	CSNK2A2	ARPC4	MYO9B	ARPC5	ARPC2	ARPC3	CSNK2B	PRKACG	PRKACB	RBX1	FRS2	PRKAR2A	TLN1	PSEN2	APH1A	APH1B	GRIN2B	PTK2	NUMB	ARTN	PSENEN	RET	CREB1	CNTN1	GFRA1	GAB2	GFRA3	GFRA2	GFRA4	RANBP9	GRIN1	ITGA2B	NRTN	MAP2K1	MAP2K2	SHC3	PSPN	GDNF	PTPRA	EIF4A3	CASC3	MAGOH	ITGB3	NCBP1	NCBP2	RBM8A	RASA1	MET	UPF3B	MAGOHB	NCAM1	RNPS1	PTPN11	MAPK12	CLTC	CLTA	YES1	SPTAN1	ANK2	PRKCA	ANK3	ANK1	SPTB	SPTBN4	SPTBN5	SPTA1	SPTBN1	SPTBN2	ITSN1	DPYSL4	DPYSL5	DPYSL2	DPYSL3	UNC5A	UNC5B	UNC5C	UNC5D	ISL1	DNM1	DNM2	NGEF	DNM3	AGAP2	PIP5K1C	L1CAM	MAPK8	MAPK7	UPF2	KIF4B	LYPLA2	KIF4A	MAPK1	DSCAML1	ZSWIM8	AGRN	MSI1	RAP1GAP	CLTCL1	CXCL12	PTPRC	CNTNAP1	HSP90AB1	NCK2	ITGAV	NEO1	ITGA2	ITGA1	PSMD8	PSMD9	ETF1	PSMD6	PSMD7	PSMD4	PSMD5	ITGA9	PSMD2	PSMD3	NTN4	PSMD1	NTN1	PSMA5	PSMA6	PSMA3	NELL2	PSMA4	PSMA1	PSMA2	EPHB2	PSME3	EPHB1	PSME4	SCN1B	PSME1	PSME2	EPHB4	SCN1A	EPHB3	PSMD10	EPHA5	PSMB11	EPHA4	PSMD12	EPHA7	PSMD11	PRKCQ	EPHA6	PSMD14	EPHA8	PSMD13	HFE2	PSMB10	PSMA7	LYN	PSMA8	SHTN1	PSMB6	KCNQ2	PSMB7	KCNQ3	PSMB4	EPHA1	PSMB5	PSMB2	EPHA3	PSMB3	EPHA2	PSMB1	PSMF1	EPHA10	SHFM1	PSMB8	SDC2	GSPT2	PSMB9	KALRN	PSMC5	GSPT1	PSMC6	RRAS	PSMC3	SCN3B	PSMC4	PSMC1	SCN3A	PSMC2	SCN2A	SCN2B	NRP1	NRP2	GIT1	CAP1	RGMB	RGMA	ENAH	ARHGEF7	RELN	GPC1	PAK7	PAK6	PAK4	CAP2	CD72	SCN9A	ITGB1	SH3GL2	PIK3R3	ITGA5	PIK3R2	PIK3R1	PIK3CA	DOK1	TYROBP	DOK4	DOK5	SCN8A	DOK6	PPP3CB	ARHGEF28	CACNA1D	FYN	CACNA1C	CACNA1H	DLG1	CACNA1G	DLG3	CACNA1I	DLG4	CACNA1S	GSK3B	PRNP	CNTN6	ST8SIA4	MSN	CNTN2	LDB1	SCN5A	ST8SIA2	PAK1	RPS6KA5	PAK3	SCN4A	SCN4B	PAK2	LAMA1	CRMP1	ABL1	SLIT1	SCN7A	SLIT3	SLIT2	PDLIM7	CDK5	TCEB2	MAPK13	TCEB1	TRIO	ALCAM	SCN11A	HOXA2	NCAN	RAC1	DOCK1	SCN10A	CDC42	FLRT3	ARHGEF11	ARHGEF12	ROCK1	RDX	SEMA4D	UPF3A	ROCK2	COL4A2	LIMK2	LIMK1	RHOC	COL4A1	RHOA	COL6A2	MYL12B	COL4A4	CLTB	RHOB	RND1	MYL6	GRB7	COL4A3	ERBB2	CHL1	COL6A1	MYH9	DOK2	MYH14	MYH11	PLXNB1	MYH10	MYL9	COL6A3	COL4A5	COL6A6	COL6A5	FARP2	SEMA5A	PLXND1	ADAM10	CFL1	GRB10	PLXNC1	SEMA6A	RPS6KA3	SEMA6D	RPS6KA6	PSEN1	CACNB1	RPS6KA2	CACNB2	RPS6KA1	CACNB3	MAPK3	CACNB4	SEMA7A	NCSTN	CUL2	PLXNA2	ABL2	PLXNA1	SRGAP3	COL9A1	COL9A3	COL9A2	SRGAP1	SHC1	PLXNA4	PLXNA3	GAB1	LAMC1	EGFR	NRAS	DAB1	PLCG1	LHX3	LHX2	SOS1	ITGA10	HRAS	PLXNB3	LHX4	LHX9	TREM2	AP2A1	VLDLR	AP2A2	TRPC7	TRPC5	TRPC6	TRPC3	AP2M1	MMP2	TRPC4	TRPC1	MMP9	EVL	SOS2	SEMA3A	AP2S1	SEMA3E	ABLIM1	ABLIM2	LAMB1	ABLIM3	SEMA4A	NFASC	AP2B1	PITPNA	RPS6KA4	DAG1	TIAM1	EZR	PFN1	PFN2	PRKACA	MYL12A	HSP90AA1	VASP	SIAH2	SIAH1	ROBO2	
S37 MUTANTS OF BETA-CATENIN AREN'T PHOSPHORYLATED%REACTOME%R-HSA-5358749.1	S37 mutants of beta-catenin aren't phosphorylated	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	CTNNB1	PPP2R1B	AMER1	AXIN1	APC	
ANTAGONISM OF ACTIVIN BY FOLLISTATIN%REACTOME DATABASE ID RELEASE 74%2473224	Antagonism of Activin by Follistatin	INHBB	INHBA	FSTL3	FST	
RAP1 SIGNALLING%REACTOME%R-HSA-392517.2	Rap1 signalling	RAF1	SIPA1	RAP1B	RAP1A	RAP1GAP2	PRKACA	YWHAB	RASGRP2	RASGRP1	RAP1GAP	YWHAZ	RAPGEF3	PRKACG	PRKACB	RAPGEF4	
ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3%REACTOME%R-HSA-9028731.1	Activated NTRK2 signals through FRS2 and FRS3	NRAS	BDNF	NTF4	PTPN11	SOS1	HRAS	FRS2	FRS3	NTRK2	
DEFECTIVE GALE CAN CAUSE EPIMERASE-DEFICIENCY GALACTOSEMIA (EDG)%REACTOME%R-HSA-5609977.2	Defective GALE can cause Epimerase-deficiency galactosemia (EDG)	GALE	
SIGNALING BY FGFR%REACTOME%R-HSA-190236.2	Signaling by FGFR	MAPK3	PTPN11	HNRNPA1	UBA52	GAB1	CBL	NRAS	PLCG1	SOS1	HRAS	UBB	UBC	RPS27A	PPP2CA	GTF2F1	GTF2F2	PPP2CB	MAPK1	KLB	ANOS1	FGFBP1	FGFBP2	FGFBP3	FGF1	RBFOX2	FGF2	FGF3	FGF4	TIA1	HNRNPM	FGF6	FGF7	HNRNPF	ESRP2	FGF9	TIAL1	HNRNPH1	FLRT3	FGF20	FGF23	FGF22	ESRP1	FGF16	MKNK1	FGF19	FGF18	SPRY2	PIK3R1	GALNT3	FGFR4	PIK3CA	POLR2A	POLR2B	FLRT2	POLR2C	FGF10	FLRT1	NCBP1	POLR2D	NCBP2	POLR2E	POLR2F	FGFRL1	POLR2G	POLR2H	POLR2I	SPRED2	PPP2R1A	POLR2J	SPRED1	POLR2K	POLR2L	FRS2	FRS3	PTBP1	BRAF	
LOSS OF PHOSPHORYLATION OF MECP2 AT T308%REACTOME DATABASE ID RELEASE 74%9022535	Loss of phosphorylation of MECP2 at T308	CAMK4	PRKACA	
GLYCEROPHOSPHOLIPID CATABOLISM%REACTOME DATABASE ID RELEASE 74%6814848	Glycerophospholipid catabolism	ENPP6	PNPLA6	GDPD1	GDPD3	GDPD5	GDE1	PNPLA7	
SIGNALLING TO ERKS%REACTOME%R-HSA-187687.1	Signalling to ERKs	RALA	RALB	MAPK3	KIDINS220	RIT1	RIT2	MAPK12	RAP1A	SHC1	YWHAB	NRAS	SOS1	HRAS	NTRK1	MAPKAPK2	MAPK13	CRK	MAPK1	NGF	MAPKAPK3	FRS2	MAPK14	MAPK11	CRKL	RAPGEF1	RALGDS	BRAF	MAP2K1	MAP2K2	SHC2	SHC3	
MRNA CAPPING%REACTOME%R-HSA-72086.3	mRNA Capping	RNMT	CCNH	RNGTT	POLR2A	POLR2B	POLR2C	POLR2D	NCBP1	NCBP2	POLR2E	POLR2F	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	SUPT5H	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	CDK7	ERCC3	ERCC2	MNAT1	
RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER%REACTOME%R-HSA-76066.2	RNA Polymerase III Transcription Initiation From Type 2 Promoter	GTF3C1	GTF3C2	GTF3C3	CRCP	GTF3C4	GTF3C5	GTF3C6	POLR2E	POLR2F	TBP	BRF1	POLR2H	POLR3GL	POLR3A	POLR3B	POLR2K	POLR2L	POLR3C	POLR3D	POLR3E	POLR1C	POLR3F	POLR3G	POLR3H	BDP1	POLR3K	
ROLE OF SECOND MESSENGERS IN NETRIN-1 SIGNALING%REACTOME DATABASE ID RELEASE 74%418890	Role of second messengers in netrin-1 signaling	TRPC7	PITPNA	TRPC5	TRPC6	PLCG1	TRPC3	TRPC4	TRPC1	DCC	NTN1	
ACTIVATION OF AMPA RECEPTORS%REACTOME DATABASE ID RELEASE 74%399710	Activation of AMPA receptors	GRIA1	GRIA2	GRIA3	GRIA4	
MPS IIIB - SANFILIPPO SYNDROME B%REACTOME DATABASE ID RELEASE 74%2206282	MPS IIIB - Sanfilippo syndrome B	NAGLU	
REGULATION OF APC C ACTIVATORS BETWEEN G1 S AND EARLY ANAPHASE%REACTOME%R-HSA-176408.3	Regulation of APC C activators between G1 S and early anaphase	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	PSMB10	PSMA7	ANAPC4	CUL1	PSMA8	ANAPC5	PSMB6	PSMB7	CCNB1	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	FZR1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	PSMC2	UBE2S	PLK1	CDC16	CDK2	CDK1	FBXO5	BUB1B	CDC20	BUB3	MAD2L1	BTRC	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
G BETA:GAMMA SIGNALLING THROUGH BTK%REACTOME%R-HSA-8964315.1	G beta:gamma signalling through BTK	GNGT1	GNGT2	GNG12	GNG11	GNG13	GNB2	GNB1	GNG3	GNB4	GNG10	GNB3	GNG2	GNB5	GNG5	GNG4	GNG7	GNG8	BTK	
SODIUM-COUPLED SULPHATE, DI- AND TRI-CARBOXYLATE TRANSPORTERS%REACTOME%R-HSA-433137.1	Sodium-coupled sulphate, di- and tri-carboxylate transporters	SLC13A5	SLC13A1	SLC13A2	SLC13A3	SLC13A4	
PAOS OXIDISE POLYAMINES TO AMINES%REACTOME%R-HSA-141334.1	PAOs oxidise polyamines to amines	PAOX	
SIGNALLING TO ERK5%REACTOME DATABASE ID RELEASE 74%198765	Signalling to ERK5	MAP2K5	MAPK7	
FCGR ACTIVATION%REACTOME DATABASE ID RELEASE 74%2029481	FCGR activation	FYN	IGKV2-28	IGKV1-12	IGKV3D-20	CD3G	IGKV2D-28	FCGR3A	IGKV4-1	FCGR1A	YES1	FGR	FCGR2A	IGKV2D-30	IGHG4	IGKV3-11	LYN	IGKV5-2	IGHG1	IGHG2	HCK	SYK	
APC:CDC20 MEDIATED DEGRADATION OF CELL CYCLE PROTEINS PRIOR TO SATISFATION OF THE CELL CYCLE CHECKPOINT%REACTOME DATABASE ID RELEASE 74%179419	APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	PSMB10	PSMA7	ANAPC4	PSMA8	ANAPC5	PSMB6	PSMB7	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	PSMC2	UBE2S	CDC16	CDK1	BUB1B	CDC20	BUB3	MAD2L1	NEK2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
BETA OXIDATION OF OCTANOYL-COA TO HEXANOYL-COA%REACTOME%R-HSA-77348.2	Beta oxidation of octanoyl-CoA to hexanoyl-CoA	HADHB	HADHA	ECHS1	HADH	ACADM	
MATURATION OF PROTEIN 3A%REACTOME DATABASE ID RELEASE 74%9694719	Maturation of protein 3a	ST3GAL4	ST6GALNAC3	ST6GALNAC4	GALNT1	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	ST6GALNAC2	
FRS-MEDIATED FGFR1 SIGNALING%REACTOME%R-HSA-5654693.3	FRS-mediated FGFR1 signaling	PTPN11	FRS2	FGF20	FRS3	FGF1	FGF23	FGF2	FGF22	FGF3	FGF4	FGF6	NRAS	FGF9	SOS1	HRAS	FGF10	
NRIF SIGNALS CELL DEATH FROM THE NUCLEUS%REACTOME%R-HSA-205043.1	NRIF signals cell death from the nucleus	RPS27A	SQSTM1	NCSTN	NGF	NGFR	TRAF6	UBA52	ITGB3BP	PSEN2	APH1A	APH1B	UBB	UBC	PSENEN	PSEN1	MAPK8	
G2 M DNA DAMAGE CHECKPOINT%REACTOME%R-HSA-69473.5	G2 M DNA damage checkpoint	BABAM1	HERC2	UIMC1	WHSC1	CHEK2	CHEK1	RNF168	RNF8	BRCC3	TP53BP1	H2AFX	CDC25C	HIST2H2BE	BRE	YWHAB	FAM175A	HIST4H4	PIAS4	CCNB1	UBE2N	HIST1H2BN	YWHAZ	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	BRCA1	HIST1H2BL	NBN	TOP3A	HIST1H2BK	HIST2H4A	HIST2H4B	BLM	RBBP8	RPA1	RPA2	MRE11A	HIST3H3	RAD50	CDK1	RPA3	SUMO1	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HIST3H2BB	HUS1	MDC1	RAD17	WEE1	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	ATM	HIST1H2BD	HIST1H2BC	UBE2V2	YWHAE	YWHAQ	SFN	YWHAH	RFC5	RFC3	RFC4	RFC2	HIST1H4K	HIST1H4L	YWHAG	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	TP53	
DEFECTIVE B4GALT7 CAUSES EDS, PROGEROID TYPE%REACTOME%R-HSA-3560783.1	Defective B4GALT7 causes EDS, progeroid type	AGRN	B4GALT7	GPC1	NCAN	BGN	VCAN	DCN	SDC4	CSPG5	CSPG4	SDC3	GPC3	SDC1	GPC2	GPC5	HSPG2	GPC4	BCAN	GPC6	SDC2	
PHOSPHORYLATION SITE MUTANTS OF CTNNB1 ARE NOT TARGETED TO THE PROTEASOME BY THE DESTRUCTION COMPLEX%REACTOME DATABASE ID RELEASE 74%4839743	phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	CTNNB1	PPP2R1B	AMER1	AXIN1	APC	
NF-KB IS ACTIVATED AND SIGNALS SURVIVAL%REACTOME DATABASE ID RELEASE 74%209560	NF-kB is activated and signals survival	NFKB1	RPS27A	SQSTM1	NFKBIA	NGF	NGFR	TRAF6	UBA52	IRAK1	IKBKB	RELA	UBB	UBC	
ESCAPE OF MTB FROM THE PHAGOCYTE%REACTOME%R-HSA-9637679.1	Escape of Mtb from the phagocyte	
RAB GEFS EXCHANGE GTP FOR GDP ON RABS%REACTOME DATABASE ID RELEASE 74%8876198	RAB GEFs exchange GTP for GDP on RABs	RABGEF1	ALS2	TRAPPC6B	RAB18	RAB3GAP2	DENND3	RAB9A	RAB21	RAB3GAP1	RAB9B	GAPVD1	RAB10	RAB14	ST5	RAB12	RAB5A	RAB13	RAB1A	RAB6A	RINL	RAB6B	RAB1B	RAB39A	CCZ1B	RIN3	ULK1	RIN1	RIN2	DENND1C	DENND1B	DENND1A	RAB39B	RAB27A	DENND2D	RAB27B	DENND2C	DENND2A	RAB3IL1	MON1A	MON1B	GDI1	GDI2	RAB8B	CHML	TRAPPC10	RAB3A	RAB7B	SBF1	RAB32	ALS2CL	RAB31	RAB35	RAB38	RAB5B	RAB5C	DENND5B	TRAPPC12	TRAPPC11	CHM	DENND5A	TRAPPC13	TRAPPC2	SBF2	TRAPPC2L	TRAPPC3	AKT2	AKT3	TRAPPC1	YWHAE	ANKRD27	AKT1	TRAPPC4	DENND6B	DENND6A	TRAPPC5	HPS1	RAB3IP	HPS4	TRAPPC8	TRAPPC9	RAB7A	DENND4B	RAB8A	DENND4A	CCZ1	RIC1	RGP1	TRAPPC6A	
BETA OXIDATION OF HEXANOYL-COA TO BUTANOYL-COA%REACTOME DATABASE ID RELEASE 74%77350	Beta oxidation of hexanoyl-CoA to butanoyl-CoA	HADHB	HADHA	ECHS1	HADH	ACADS	
NEUROPHILIN INTERACTIONS WITH VEGF AND VEGFR%REACTOME%R-HSA-194306.1	Neurophilin interactions with VEGF and VEGFR	NRP1	NRP2	FLT1	KDR	
DISEASES OF IMMUNE SYSTEM%REACTOME DATABASE ID RELEASE 74%5260271	Diseases of Immune System	LY96	NFKB1	NFKBIA	IRAK4	TICAM1	TIRAP	TLR1	TRAF3	CD14	TLR4	TLR10	TLR6	TLR5	NFKB2	IKBKB	RELA	TLR3	MYD88	TLR2	UNC93B1	IKBKG	BTK	CD36	CHUK	
REMOVAL OF THE FLAP INTERMEDIATE%REACTOME%R-HSA-69166.2	Removal of the Flap Intermediate	POLA2	DNA2	FEN1	PCNA	RPA1	RPA2	POLD3	POLD4	RPA3	POLD1	POLD2	PRIM2	PRIM1	POLA1	
TRANSPORT OF NUCLEOTIDE SUGARS%REACTOME%R-HSA-727802.1	Transport of nucleotide sugars	SLC35B4	SLC35D1	SLC35D2	SLC35A2	SLC35A1	SLC35A3	SLC35C1	SLC35B3	SLC35B2	
BLOCH PATHWAY%REACTOME%R-HSA-6807047.1	Bloch pathway	EBP	SC5D	DHCR24	DHCR7	
DEFECTIVE F8 SULFATION AT Y1699%REACTOME DATABASE ID RELEASE 74%9674519	Defective F8 sulfation at Y1699	TPST2	TPST1	F8	
SUPPRESSION OF APOPTOSIS%REACTOME%R-HSA-9635465.1	Suppression of apoptosis	TRIM27	MAPK3	RNF213	MAPK1	GSK3A	SFPQ	CTSG	
DEFECTIVE SLC12A6 CAUSES AGENESIS OF THE CORPUS CALLOSUM, WITH PERIPHERAL NEUROPATHY (ACCPN)%REACTOME%R-HSA-5619039.1	Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)	SLC12A6	
IRAK4 DEFICIENCY (TLR5)%REACTOME DATABASE ID RELEASE 74%5603037	IRAK4 deficiency (TLR5)	TLR5	IRAK4	MYD88	TLR10	
VEGFR2 MEDIATED CELL PROLIFERATION%REACTOME%R-HSA-5218921.3	VEGFR2 mediated cell proliferation	PRKCB	KDR	PRKCA	AHCYL1	PRKCZ	ITPR1	ITPR2	ITPR3	NRAS	PDPK1	PLCG1	SPHK1	HRAS	PRKCD	RASA1	
SIGNALING BY HIPPO%REACTOME%R-HSA-2028269.1	Signaling by Hippo	YAP1	STK3	LATS1	LATS2	WWTR1	NPHP4	WWC1	TJP1	YWHAB	DVL2	AMOTL2	AMOTL1	TJP2	SAV1	CASP3	MOB1B	MOB1A	YWHAE	STK4	
EGFR INTERACTS WITH PHOSPHOLIPASE C-GAMMA%REACTOME%R-HSA-212718.2	EGFR interacts with phospholipase C-gamma	TGFA	AREG	EGFR	EPGN	PLCG1	EREG	BTC	EGF	HBEGF	
LATENT INFECTION - OTHER RESPONSES OF MTB TO PHAGOCYTOSIS%REACTOME%R-HSA-1222499.2	Latent infection - Other responses of Mtb to phagocytosis	LTF	
POTASSIUM TRANSPORT CHANNELS%REACTOME DATABASE ID RELEASE 74%1296067	Potassium transport channels	KCNJ10	KCNJ1	KCNJ16	
MATURATION OF NUCLEOPROTEIN%REACTOME%R-HSA-9694631.1	Maturation of nucleoprotein	SUMO1	UBE2I	PARP16	PARP14	PARP10	PARP6	PARP4	GSK3B	PARP9	PARP8	
SCN4%REACTOME DATABASE ID RELEASE 74%3282872	SCN4	G6PC3	
ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION%REACTOME DATABASE ID RELEASE 74%68616	Assembly of the ORC complex at the origin of replication	ORC4	ORC6	ORC1	ORC3	ORC2	ORC5	
LOSS OF NLP FROM MITOTIC CENTROSOMES%REACTOME DATABASE ID RELEASE 74%380259	Loss of Nlp from mitotic centrosomes	CSNK1E	DYNLL1	TUBG1	CKAP5	TUBA4A	HAUS2	HAUS1	AKAP9	CEP63	MAPRE1	SFI1	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	HAUS8	HAUS7	PRKAR2B	CEP70	CEP72	CEP192	PCNT	CEP76	CLASP1	CEP78	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	CEP57	YWHAE	CETN2	CEP164	CCP110	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	NINL	CEP290	YWHAG	CDK5RAP2	OFD1	HSP90AA1	CEP135	TUBB	CEP131	HAUS4	HAUS3	CSNK1D	HAUS6	HAUS5	
MITOTIC METAPHASE AND ANAPHASE%REACTOME%R-HSA-2555396.2	Mitotic Metaphase and Anaphase	DYNC1LI1	DYNLL1	DYNC1LI2	LMNB1	CKAP5	TUBA4A	ZW10	NUP62	UBE2D1	CDC23	EMD	CDC26	NDC1	MAPRE1	CDC27	SEC13	NUP133	UBA52	ANAPC7	UBE2E1	PAFAH1B1	DYNC1I2	ANAPC4	ANAPC5	CCNB2	NUP54	CCNB1	TUBA4B	ANAPC1	UBB	ANAPC2	ANAPC15	ANAPC16	UBC	ANAPC10	ANAPC11	RPS27A	TUBAL3	PPP2CA	KIF18A	CLASP1	PPP2CB	DYNC1H1	UBE2C	NUP43	RANBP2	NDE1	UBE2S	PLK1	CDC16	TUBB4B	TUBA8	TUBB4A	NUP35	CLIP1	CDK1	NUP37	TUBB8P12	TUBB8	TUBA3E	TUBA1C	DYNLL2	TUBB6	TUBA1B	TUBB3	TUBB1	ANKLE2	PPP2R2A	SIRT2	KIF2A	TUBB2B	KIF2C	TUBB2A	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	CLASP2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	DYNC1I1	PSMD2	PSMD3	PSMD1	PSMA5	CENPE	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	RPS27	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	RCC1	PSMA7	XPO1	PSMA8	PSMB6	TNPO1	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	IST1	SPAST	CC2D1B	SUMO1	UBE2I	ERCC6L	ZWILCH	CASC5	SMC3	KNTC1	MAD1L1	CDCA5	CDCA8	PDS5B	PDS5A	PMF1	VPS4A	SKA1	SKA2	DSN1	RAD21	RCC2	NDC80	ZWINT	STAG1	STAG2	AHCTF1	SGOL2	CHMP2B	SGOL1	NUF2	CHMP2A	CHMP4C	WAPAL	CHMP4B	SPDL1	NDEL1	NUDC	CHMP3	CHMP4A	RANGAP1	SMC1A	CHMP6	INCENP	CHMP7	BIRC5	ITGB3BP	MIS12	CENPA	AURKB	NSL1	CENPC	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	CENPN	CENPO	B9D2	CENPP	CENPQ	SPC24	SPC25	PPP1CC	PTTG1	FBXO5	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	LBR	KPNB1	RAN	NUP107	NUP188	PPP2R1B	BANF1	VRK1	LEMD3	LEMD2	NUP93	ESPL1	NUP205	POM121	NUP160	NUP85	TUBA1A	PPP2R1A	NUP155	
PLATELET CALCIUM HOMEOSTASIS%REACTOME%R-HSA-418360.1	Platelet calcium homeostasis	ATP2A1	SLC8A3	SRI	P2RX6	P2RX5	STIM1	P2RX3	P2RX2	TRPC7	P2RX1	P2RX7	ORAI2	ORAI1	TRPC6	P2RX4	TRPC3	ATP2B4	ATP2B3	ATP2B2	ATP2B1	ITPR1	ITPR2	ITPR3	SLC8A1	SLC8A2	ATP2A3	ATP2A2	
REVERSIBLE HYDRATION OF CARBON DIOXIDE%REACTOME%R-HSA-1475029.1	Reversible hydration of carbon dioxide	CA12	CA5B	CA1	CA3	CA5A	CA7	CA6	CA14	CA13	CA2	CA9	CA4	
VEGFA-VEGFR2 PATHWAY%REACTOME%R-HSA-4420097.4	VEGFA-VEGFR2 Pathway	PAK3	PAK2	MAPK12	PRKCZ	JUP	CTNND1	HSPB1	NRAS	CTNNB1	PLCG1	SPHK1	HRAS	PRKCD	MAPKAPK2	CDH5	MAPK13	KDR	AHCYL1	CYFIP2	NCKAP1	CYFIP1	RAC1	MAPK14	MAPK11	PIK3CB	CTNNA1	SHB	VAV1	BRK1	DOCK1	NCK1	SH2D2A	VAV3	AXL	CDC42	VAV2	ELMO1	ELMO2	SHC2	NCKAP1L	PRKCB	WASF1	WASF2	WASF3	PRKCA	ROCK1	PTK2B	ROCK2	BAIAP2	CYBA	RHOA	ABI2	ABI1	PRR5	NCF1	PDPK1	NCF2	MAPKAP1	NCF4	PIK3R2	PIK3R1	MTOR	PIK3CA	CRK	NOS3	AKT2	PRKACG	AKT3	CYBB	BCAR1	ITGB3	MLST8	PRKACB	PXN	THEM4	AKT1	TRIB3	FYN	CAV1	RICTOR	MAPKAPK3	NCK2	PRKACA	ITGAV	ITPR1	ITPR2	ITPR3	HSP90AA1	RASA1	PTK2	PAK1	
BIOSYNTHESIS OF A2E, IMPLICATED IN RETINAL DEGRADATION%REACTOME%R-HSA-2466712.1	Biosynthesis of A2E, implicated in retinal degradation	NAPEPLD	
TALDO1 DEFICIENCY: FAILED CONVERSION OF SH7P, GA3P TO FRU(6)P, E4P%REACTOME%R-HSA-6791055.2	TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P	TALDO1	
BASE EXCISION REPAIR%REACTOME%R-HSA-73884.2	Base Excision Repair	HIST2H2AC	H2AFJ	XRCC1	LIG3	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	RPA1	RPA2	HIST3H3	PARP1	PARG	PNKP	ADPRHL2	RPA3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	MPG	HIST1H2AJ	OGG1	TINF2	TERF1	TERF2	NEIL3	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	PARP2	H2AFB1	NEIL2	NEIL1	RFC5	TDG	RFC3	MBD4	FEN1	SMUG1	PCNA	RFC4	RFC1	LIG1	RFC2	HIST1H4K	HIST1H4L	POLE4	POLD3	POLB	POLD4	POLE2	POLD1	H2BFS	APEX1	HIST1H4A	POLE3	POLD2	HIST1H4B	POLE	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	NTHL1	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA%REACTOME%R-HSA-111448.2	Activation of NOXA and translocation to mitochondria	TFDP1	TFDP2	PMAIP1	E2F1	TP53	
IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION%REACTOME%R-HSA-975163.1	IRAK2 mediated activation of TAK1 complex upon TLR7 8 or 9 stimulation	LY96	RPS27A	TICAM1	CD14	TRAF6	TLR4	UBA52	UBB	TAB3	TAB2	TAB1	UBC	MAP3K7	TICAM2	IRAK2	
ION TRANSPORT BY P-TYPE ATPASES%REACTOME%R-HSA-936837.3	Ion transport by P-type ATPases	ATP8A2	ATP8A1	ATP12A	CAMK2G	SLN	ATP11C	ATP11B	ATP11A	ATP8B4	ATP8B3	ATP8B2	ATP8B1	ATP4B	ATP4A	CUTC	ATP2A3	ATP2A2	ATP2A1	ATP7B	PDZD11	ATP7A	ATP1B3	ATP1B2	ATP1B1	ATP1A4	ATP1A3	ATP1A2	ATP1A1	ATP10D	ATP10B	ATP10A	ATP2C2	SRI	ATP2C1	FXYD4	PLN	FXYD3	FXYD2	ATP9B	FXYD1	FXYD7	ATP9A	FXYD6	ATP13A1	ATP2B4	ATP2B3	ATP2B2	CAMK2A	ATP2B1	ATP13A4	ATP13A5	ATP13A2	CAMK2B	CAMK2D	
DEGRADATION OF AXIN%REACTOME DATABASE ID RELEASE 74%4641257	Degradation of AXIN	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	TNKS2	TNKS	AXIN2	SMURF2	PSMD8	RNF146	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	AXIN1	PSMA5	
DEFECTS IN COBALAMIN (B12) METABOLISM%REACTOME DATABASE ID RELEASE 74%3296469	Defects in cobalamin (B12) metabolism	MTRR	MMAB	GIF	MTR	CUBN	LMBRD1	AMN	MMACHC	MMADHC	ABCD4	MMAA	TCN2	MUT	CD320	
HDL CLEARANCE%REACTOME DATABASE ID RELEASE 74%8964011	HDL clearance	CUBN	AMN	HDLBP	APOA1	
DEFECTIVE CSF2RA CAUSES SMDP4%REACTOME DATABASE ID RELEASE 74%5688890	Defective CSF2RA causes SMDP4	SFTPC	SFTPD	CSF2RB	CSF2RA	SFTPA2	SFTA3	SFTPA1	SFTPB	
MPS IX - NATOWICZ SYNDROME%REACTOME DATABASE ID RELEASE 74%2206280	MPS IX - Natowicz syndrome	HYAL1	
UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN%REACTOME%R-HSA-5336415.1	Uptake and function of diphtheria toxin	HSP90AA1	HSP90AB1	TXNRD1	CD9	EEF2	HBEGF	
INTERACTION BETWEEN L1 AND ANKYRINS%REACTOME DATABASE ID RELEASE 74%445095	Interaction between L1 and Ankyrins	SCN4A	SCN4B	SPTAN1	ANK2	ANK3	SCN1B	ANK1	SPTB	SPTBN4	SPTBN5	SCN1A	SPTA1	SCN7A	NFASC	SPTBN1	SPTBN2	SCN9A	L1CAM	KCNQ2	KCNQ3	SCN8A	SCN11A	SCN3B	SCN3A	SCN2A	SCN2B	NRCAM	SCN10A	SCN5A	
SIGNALING BY NOTCH1 T(7;9)(NOTCH1:M1580_K2555) TRANSLOCATION MUTANT%REACTOME DATABASE ID RELEASE 74%2660825	Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	ADAM10	DLL1	DLL4	ADAM17	JAG2	JAG1	NOTCH1	
ABNORMAL CONVERSION OF 2-OXOGLUTARATE TO 2-HYDROXYGLUTARATE%REACTOME DATABASE ID RELEASE 74%2978092	Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate	IDH1	
ACTIVATED NTRK2 SIGNALS THROUGH PI3K%REACTOME DATABASE ID RELEASE 74%9028335	Activated NTRK2 signals through PI3K	GAB1	BDNF	NTF4	PIK3R1	PIK3CA	NTRK2	
NTRK2 ACTIVATES RAC1%REACTOME%R-HSA-9032759.1	NTRK2 activates RAC1	BDNF	RAC1	NTRK2	DOCK3	
INTERLEUKIN-18 SIGNALING%REACTOME%R-HSA-9012546.2	Interleukin-18 signaling	IL18RAP	IL37	IL18	IL4	IL18R1	IL18BP	IL13	ALOX5	
DEFECTIVE TCN2 CAUSES HEREDITARY MEGALOBLASTIC ANEMIA%REACTOME DATABASE ID RELEASE 74%3359454	Defective TCN2 causes hereditary megaloblastic anemia	TCN2	
DOWNSTREAM SIGNALING OF ACTIVATED FGFR3%REACTOME%R-HSA-5654708.1	Downstream signaling of activated FGFR3	PTPN11	FRS2	FGF20	FRS3	FGF1	FGF23	FGF2	GAB1	FGF4	FGF16	NRAS	FGF9	PLCG1	SOS1	HRAS	FGF18	PIK3R1	PIK3CA	
GLUTAMATE AND GLUTAMINE METABOLISM%REACTOME DATABASE ID RELEASE 74%8964539	Glutamate and glutamine metabolism	GLS	GOT2	GLUL	OAT	PYCRL	GLS2	CCBL1	RIMKLA	RIMKLB	PYCR1	PYCR2	GLUD1	GLUD2	
ACTIVATED NTRK2 SIGNALS THROUGH CDK5%REACTOME%R-HSA-9032845.1	Activated NTRK2 signals through CDK5	TIAM1	CDK5	BDNF	RAC1	CDK5R1	NTRK2	
HYALURONAN UPTAKE AND DEGRADATION%REACTOME%R-HSA-2160916.3	Hyaluronan uptake and degradation	LYVE1	SLC9A1	HEXB	CD44	CHP1	HEXA	HYAL1	HYAL3	HYAL2	HMMR	STAB2	GUSB	
DEFECTIVE F8 BINDING TO VON WILLEBRAND FACTOR%REACTOME DATABASE ID RELEASE 74%9672393	Defective F8 binding to von Willebrand factor	F8	VWF	
MOLYBDENUM COFACTOR BIOSYNTHESIS%REACTOME%R-HSA-947581.1	Molybdenum cofactor biosynthesis	GPHN	MOCOS	MOCS2	MOCS3	
PHASE 3 - RAPID REPOLARISATION%REACTOME DATABASE ID RELEASE 74%5576890	Phase 3 - rapid repolarisation	KCNH2	AKAP9	KCNE1	KCNE2	KCNE3	KCNE4	KCNE5	KCNQ1	
ERBB2 ACTIVATES PTK6 SIGNALING%REACTOME DATABASE ID RELEASE 74%8847993	ERBB2 Activates PTK6 Signaling	NRG1	ERBB2	EGFR	NRG2	NRG3	NRG4	EREG	BTC	EGF	PTK6	HBEGF	
OXIDATIVE STRESS INDUCED SENESCENCE%REACTOME%R-HSA-2559580.4	Oxidative Stress Induced Senescence	PHC2	HIST2H2AC	FOS	PHC1	H2AFJ	TNRC6C	MOV10	UBA52	AGO3	H2AFZ	PHC3	AGO4	H2AFX	H2AFV	AGO1	HIST2H2BE	HIST4H4	TNRC6A	EZH2	TNRC6B	UBB	HIST1H2BN	HIST1H2BM	HIST1H2BO	UBC	RING1	HIST1H2BJ	HIST1H2BI	MAPK9	CDKN2D	HIST1H2BL	MAPK8	CDKN2B	CDKN2C	RPS27A	HIST1H2BK	SUZ12	MAPK10	HIST2H4A	HIST2H4B	MAPK1	IFNB1	CDK6	CDKN2A	MAPKAPK5	E2F1	MAPK3	MDM2	MDM4	MAP3K5	TNIK	MAPKAPK2	E2F2	TXN	MINK1	MAPK14	MAP4K4	MAPK11	TFDP1	TFDP2	HIST1H2AE	CBX8	HIST1H2AD	KDM6B	CBX6	HIST3H2BB	CBX4	HIST1H2AC	CBX2	HIST1H2AB	HIST1H2AJ	E2F3	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	BMI1	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	MAP2K3	HIST1H3A	RBBP4	MAP2K4	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	RBBP7	HIST1H3B	MAPKAPK3	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	CDK4	RNF2	HIST1H4L	MAP2K7	MAP2K6	JUN	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	EED	HIST2H2AA3	TP53	HIST2H2AA4	
FGFR2 MUTANT RECEPTOR ACTIVATION%REACTOME DATABASE ID RELEASE 74%1839126	FGFR2 mutant receptor activation	FGF20	FGF23	FGF22	FGF16	FGF18	POLR2A	POLR2B	POLR2C	FGF10	POLR2D	NCBP1	NCBP2	POLR2E	POLR2F	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	FGF1	FGF2	FGF3	FGF4	FGFR2	FGF6	FGF7	FGF9	
PACKAGING OF TELOMERE ENDS%REACTOME%R-HSA-171306.3	Packaging Of Telomere Ends	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST3H3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	TINF2	TERF1	TERF2	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
ATTENUATION PHASE%REACTOME DATABASE ID RELEASE 74%3371568	Attenuation phase	HSPA1L	FKBP4	PTGES3	HSP90AA1	HSPA2	DNAJB1	HSP90AB1	CREBBP	HSPA8	EP300	HSBP1	HSF1	
CDC20:PHOSPHO-APC C MEDIATED DEGRADATION OF CYCLIN A%REACTOME%R-HSA-174184.2	Cdc20:Phospho-APC C mediated degradation of Cyclin A	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	PSMB10	PSMA7	ANAPC4	PSMA8	ANAPC5	PSMB6	PSMB7	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	PSMC2	UBE2S	CDC16	CDK1	BUB1B	CDC20	BUB3	MAD2L1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
PLATELET HOMEOSTASIS%REACTOME DATABASE ID RELEASE 74%418346	Platelet homeostasis	PLA2G4A	PTPN11	GNG12	GNG11	GNG13	GNB2	GNB1	GNB4	PDE1B	GNB3	PDE1A	GUCY1B3	GNB5	P2RX6	P2RX5	GUCY1A3	STIM1	GUCY1A2	P2RX3	P2RX2	TRPC7	P2RX1	ORAI2	PPP2CA	ORAI1	TRPC6	PPP2CB	TRPC3	MAPK14	FGR	PDE2A	PPP2R1B	ATP2A3	ATP2A2	ATP2A1	APOB	SLC8A3	PDE5A	LRP8	MRVI1	PDE9A	PDE11A	PTPN6	SRI	PAFAH2	NOS1	NOS2	NOS3	PTGIR	GNGT1	PDE10A	P2RX7	GNGT2	KCNMB1	P2RX4	PRKG2	KCNMB2	KCNMB3	PPP2R1A	KCNMB4	ATP2B4	ATP2B3	ATP2B2	PPP2R5E	ATP2B1	PPP2R5B	PPP2R5A	ITPR1	PPP2R5D	ITPR2	ITPR3	PPP2R5C	GNAS	GNG3	GNG10	GNG2	GNG5	GNG4	SLC8A1	GNG7	SLC8A2	KCNMA1	GNG8	
INFECTION WITH MYCOBACTERIUM TUBERCULOSIS%REACTOME DATABASE ID RELEASE 74%9635486	Infection with Mycobacterium tuberculosis	MAPK3	HGS	PGK1	ATP6V1H	UBA52	TLR2	UBB	RAB5A	NOS2	UBC	CTSG	RPS27A	KPNA1	DUSP16	KPNB1	MAPK1	B2M	VPS33B	SFPQ	CORO1A	RAB7A	TRIM27	MRC1	ENO1	RNF213	LTF	GSK3A	
POU5F1 (OCT4), SOX2, NANOG ACTIVATE GENES RELATED TO PROLIFERATION%REACTOME%R-HSA-2892247.3	POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	SOX2	SALL1	SALL4	NANOG	FOXD3	EPHA1	ZIC3	POU5F1	TDGF1	DPPA4	FGF2	STAT3	
INTERLEUKIN-36 PATHWAY%REACTOME%R-HSA-9014826.1	Interleukin-36 pathway	IL36A	IL36B	IL36RN	IL36G	IL1F10	IL1RL2	
G ALPHA (Q) SIGNALLING EVENTS%REACTOME DATABASE ID RELEASE 74%416476	G alpha (q) signalling events	EDNRA	EDNRB	UTS2R	UTS2B	MAPK7	SAA1	MCHR1	MAPK1	NTSR1	NTSR2	NMB	XCR1	NMBR	NMS	NMU	BRS3	CCKAR	GRP	FFAR3	FFAR2	FFAR4	FFAR1	EDN1	EDN2	EDN3	CCKBR	CYSLTR2	KISS1R	F2RL1	PMCH	GHSR	NTS	GCG	PRKCQ	RASGRP2	RASGRP1	OPN4	NMUR2	PRKCD	NMUR1	GPRC6A	KALRN	NPFFR2	MLNR	NPFFR1	NPFF	QRFPR	HCRT	QRFP	HCRTR2	PROKR1	HCRTR1	PROKR2	BDKRB2	BDKRB1	GPR68	GPR65	BTK	RGS18	RGS17	RGS19	RGS13	RGS16	UTS2	GNA14	GNA15	GNA11	GNAQ	RGS21	F2RL2	F2RL3	AVP	PIK3R3	PIK3R2	PIK3R1	PIK3CA	KISS1	GNGT1	GNGT2	PLCB3	PLCB1	PLCB2	ITPR1	ITPR2	ITPR3	RGSL1	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	OXTR	AVPR1B	OXT	AVPR1A	LPAR1	CREB1	LPAR2	GNG12	LPAR3	GNG11	GNG13	MGLL	GNB2	GNB1	PLCB4	LPAR5	GNB4	GNRH2	GNB3	GNRH1	ADRBK1	GNB5	MLN	TRIO	GNRHR	HBEGF	RGS4	RGS5	RGS2	PTGFR	RGS3	RGS1	TBXA2R	PTGER1	CASR	PTAFR	ARHGEF25	MCHR2	GRK5	TAC3	TAC1	GRM1	LTB4R	ANXA1	GRM5	FPR2	AGT	DGKG	DGKE	DGKD	DAGLA	RPS6KA3	DGKB	DGKA	RPS6KA2	ABHD6	RPS6KA1	ABHD12	PRKCH	MAPK3	PRKCE	DGKZ	DGKQ	DAGLB	DGKK	DGKI	DGKH	CCK	AGTR1	EGFR	CHRM3	NRAS	CHRM1	CHRM5	HTR2B	SOS1	HRAS	HTR2C	ADRA1D	HTR2A	GRPR	ADRA1B	ADRA1A	PROK2	HRH1	PROK1	TRPC7	TRPC6	TRPC3	TRHR	MMP3	GPR39	GPR132	GAST	TACR2	TACR1	TACR3	NPSR1	GPR143	NPS	P2RY11	PRKCA	GPR4	CYSLTR1	GPR17	P2RY10	LTB4R2	LPAR4	APP	P2RY6	LPAR6	P2RY2	P2RY1	KNG1	TRH	F2R	F2	XCL2	XCL1	
SYNTHESIS OF PROSTAGLANDINS (PG) AND THROMBOXANES (TX)%REACTOME%R-HSA-2162123.2	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	PTGS2	HPGDS	PTGDS	CBR1	PTGIS	TBXAS1	PTGR2	PTGES	PTGS1	FAM213B	PTGES2	PTGES3	AKR1C3	CYP8B1	HPGD	
MHC CLASS II ANTIGEN PRESENTATION%REACTOME DATABASE ID RELEASE 74%2132295	MHC class II antigen presentation	DYNC1LI1	DYNLL1	DYNC1LI2	SEC23A	DNM1	DNM2	KIF20A	DNM3	SEC13	SEC24B	SEC24A	DYNC1I2	KLC1	DCTN2	KLC4	DCTN3	KLC3	KLC2	KIF3B	RACGAP1	SEC24D	KIF3C	SEC24C	KIF18A	IFI30	KIF4B	KIF4A	DYNC1H1	ARF1	KIF11	KIF15	CAPZB	KIF23	KIF22	CTSC	DYNLL2	HLA-DMA	HLA-DMB	KIF2A	HLA-DOA	KIF2C	HLA-DOB	LAG3	KIF2B	DCTN6	DCTN5	DCTN1	DCTN4	DYNC1I1	OSBPL1A	CENPE	CAPZA3	KIF26A	CAPZA1	CAPZA2	CTSO	ACTR10	CTSH	CTSF	CTSE	RILP	CTSV	CTSS	SEC31A	CTSL	CTSK	AP2A1	AP2A2	CTSD	CTSB	AP1G1	AP2M1	AP1B1	AP1S2	AP1S1	AP1S3	CLTC	CLTA	AP1M2	ACTR1B	AP1M1	CANX	SAR1B	HLA-DPA1	HLA-DQB2	HLA-DQB1	HLA-DQA2	AP2S1	HLA-DQA1	HLA-DRB5	HLA-DRB4	HLA-DPB1	HLA-DRA	HLA-DRB3	HLA-DRB1	AP2B1	SPTBN2	CD74	SH3GL2	ACTR1A	KIF3A	RAB7A	KIF5B	KIF5A	LGMN	KIFAP3	CTSA	
RNA POLYMERASE I PROMOTER OPENING%REACTOME DATABASE ID RELEASE 74%73728	RNA Polymerase I Promoter Opening	MAPK3	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	MBD2	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	HIST1H3F	HIST1H3G	UBTF	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
SUMO IS CONJUGATED TO E1 (UBA2:SAE1)%REACTOME DATABASE ID RELEASE 74%3065676	SUMO is conjugated to E1 (UBA2:SAE1)	UBA2	SUMO1	SUMO3	SAE1	SUMO2	
DEFECTIVE HEXB CAUSES GM2G2%REACTOME%R-HSA-3656248.1	Defective HEXB causes GM2G2	HEXB	
SYNTHESIS OF KETONE BODIES%REACTOME DATABASE ID RELEASE 74%77111	Synthesis of Ketone Bodies	HMGCL	ACSS3	BDH2	BDH1	HMGCS2	HMGCLL1	AACS	ACAT1	
GLI3 IS PROCESSED TO GLI3R BY THE PROTEASOME%REACTOME%R-HSA-5610785.1	GLI3 is processed to GLI3R by the proteasome	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	CSNK1A1	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	CUL1	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	PRKACG	PRKACB	RBX1	GSK3B	PRKACA	BTRC	PSMD8	SKP1	GLI3	PSMD9	PSMD6	PSMD7	PSMD4	SUFU	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS%REACTOME DATABASE ID RELEASE 74%9616222	Transcriptional regulation of granulopoiesis	CDKN1A	HIST2H2AC	CREB1	CBFB	H2AFJ	GATA2	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	FLI1	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	MYC	HIST2H4B	CDK2	TFDP1	TFDP2	HIST1H2AE	CEBPA	HIST1H2AD	HIST3H2BB	HIST1H2AC	CEBPE	HIST1H2AB	RXRA	CEBPB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	KLF5	HIST1H2BG	HIST2H3D	GFI1	HIST1H2BB	HIST2H3C	HIST1H2BA	IL6R	HIST1H2BD	KMT2A	HIST1H2BC	H2AFB1	HIST1H3J	TAL1	HIST1H3A	RUNX1	RARA	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	LEF1	H3F3B	HIST1H4K	CDK4	HIST1H4L	DEK	CSF3R	STAT3	H3F3A	H2BFS	HIST1H4A	SPI1	HIST1H4B	HIST1H4H	MYB	HIST1H4I	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	E2F1	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
G1 S TRANSITION%REACTOME DATABASE ID RELEASE 74%69206	G1 S Transition	MCM7	MCM8	TYMS	SKP2	CDC7	UBA52	CCNA2	CCNA1	CCNE2	CCNE1	MCM3	MCM4	CUL1	MCM5	CCNB1	MCM6	UBB	MCM2	UBC	ORC5	ORC4	RPS27A	ORC6	PPP2CA	ORC1	MYC	ORC3	PPP2CB	ORC2	CDT1	CDC6	RPA1	RPA2	CDK2	TK1	PTK6	CDK1	RPA3	HDAC1	PRIM2	PRIM1	POLA1	CABLES1	POLA2	WEE1	FBXO5	GMNN	MCM10	DBF4	RPA4	PCNA	POLE4	PSMD8	POLE2	PSMD9	CDC45	PSMD6	POLE3	PSMD7	PSMD4	POLE	PSMD5	PSMD2	PSMD3	PSMD1	E2F1	PSMA5	PSMA6	PSMA3	CDKN1A	PSMA4	CDKN1B	PSMA1	PSMA2	PSME3	PSME1	CDC25A	PSME2	PSMD10	PSMD12	PSMD11	PSMD14	PSMD13	LIN54	RBL2	LIN37	MAX	RBL1	PSMB10	LIN9	PSMA7	E2F4	E2F5	LIN52	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	E2F6	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	RB1	TFDP1	TFDP2	PPP2R1B	CKS1B	PPP2R3B	CCNH	DHFR	AKT2	AKT3	RBBP4	AKT1	PPP2R1A	CCND1	CDK4	RRM2	SKP1	CDK7	MNAT1	
NOSIP MEDIATED ENOS TRAFFICKING%REACTOME DATABASE ID RELEASE 74%203754	NOSIP mediated eNOS trafficking	NOSIP	NOS3	
FORMATION OF APOPTOSOME%REACTOME DATABASE ID RELEASE 74%111458	Formation of apoptosome	MAPK3	AVEN	APAF1	DIABLO	CARD8	MAPK1	APIP	XIAP	UACA	CASP9	CYCS	
CELL CYCLE%REACTOME DATABASE ID RELEASE 74%1640170	Cell Cycle	CSNK1E	DYNLL1	TUBG1	CKAP5	TUBA4A	HAUS2	PPME1	PHLDA1	HAUS1	AKAP9	LCMT1	CEP63	CDK11A	MAPRE1	AJUBA	SFI1	UBA52	OPTN	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	CUL1	AURKA	CCNB2	CCNB1	UBB	HAUS8	HAUS7	PRKAR2B	RTEL1	PRDM9	UBC	CEP70	SPO11	CEP72	BRCA1	CEP192	BRCA2	RPS27A	NBN	TOP3A	PCNT	CEP76	TEX15	MSH4	CLASP1	CEP78	DMC1	PLK4	MSH5	BLM	DYNC1H1	ODF2	PSMC3IP	RBBP8	CEP152	NDE1	RPA1	PLK1	RPA2	TUBB4B	MRE11A	TUBB4A	MND1	MLH1	NEDD1	CENPJ	MLH3	CDK1	RAD50	PTK6	FGFR1OP	RAD51	CEP41	RPA3	JAK2	TUBB8P12	MDC1	TUBB8	TUBA3E	TUBA1C	TUBB6	TUBA1B	TUBB3	TUBB1	ANKLE2	DAXX	PPP2R2A	SIRT2	TUBB2B	TUBB2A	TPX2	BUB1B	UBE2V2	CDC20	BUB3	MAD2L1	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	CLASP2	POLR2K	POLR2L	FKBP6	RPS27	YWHAB	RCC1	XPO1	TNPO1	PIAS4	YWHAZ	FBXL7	CSNK2A1	CSNK2A2	CSNK2B	HSPA2	RBX1	ERCC6L	ZWILCH	CASC5	SMC3	KNTC1	MAD1L1	CDCA5	CDCA8	EML4	PDS5B	TUBGCP2	EP300	PDS5A	NCAPG	VPS4A	PMF1	SKA1	NCAPH	SKA2	TUBGCP5	TUBGCP6	DSN1	RAD21	TUBGCP3	TUBGCP4	RCC2	NDC80	TUBG2	MZT2B	ZWINT	MZT2A	STAG1	STAG2	NME7	MZT1	AHCTF1	NCAPD2	SGOL2	CHMP2B	SGOL1	NUF2	CHMP2A	WAPAL	CHMP4C	SPDL1	CHMP4B	NDEL1	NUDC	CHMP3	RANGAP1	CHMP4A	SMC1A	FBXL18	CHMP6	INCENP	CHMP7	BIRC5	ITGB3BP	SMARCA5	MIS12	CENPA	AURKB	NSL1	CENPC	BUB1	CENPT	CLSPN	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	CENPN	CENPO	B9D2	CENPP	CENPQ	SPC24	SPC25	LPIN1	LPIN2	PPP1CC	LPIN3	PTTG1	ESCO1	ESCO2	CCND2	RFC5	RFC3	FEN1	PCNA	RFC4	RFC1	PPP2R5E	LIG1	RFC2	PPP2R5B	PPP2R5A	POLE4	PPP2R5D	POLD3	PPP2R5C	POLD4	POLE2	POLD1	POLE3	POLD2	POLE	CDKN1A	CDKN1B	PHF20	CHEK2	CHEK1	RUVBL1	ZNF385A	CDC25A	PCBP4	MDM2	MDM4	CDC25C	RBL2	RBL1	E2F4	NPM1	GTSE1	FKBPL	KPNB1	RAN	RB1	NUP107	NUP188	SMC4	SMC2	GOLGA2	PPP2R1B	HIST1H2AE	HIST1H2AD	BANF1	HIST3H2BB	HIST1H2AC	HIST1H2AB	RAB2A	NUP214	NUP210	PRKCB	HIST1H2AJ	VRK1	PRKCA	LEMD3	LEMD2	NUP93	CTDNEP1	HIST2H3A	HIST1H2BF	GAR1	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	BLZF1	HIST1H2BD	HIST1H2BC	NUP205	POM121	CCNH	H2AFB1	SET	DHFR	HIST1H3J	AAAS	ARPP19	NUP160	HIST1H3A	NUP85	RBBP4	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	RBBP7	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	NEK9	NUP155	H3F3B	HMMR	HIST1H4K	HIST1H4L	NEK6	NCAPH2	NEK7	H3F3A	CDK7	NUP153	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	DKC1	HIST1H4E	NHP2	HIST1H4F	HIST2H2AA3	HIST2H2AA4	SETD8	DYNC1LI1	NUMA1	NCAPG2	DYNC1LI2	LMNB1	HIST2H2AC	MCM7	H2AFJ	MCM8	ZW10	NUP62	ENSA	UBE2D1	NOP10	EMD	CDC23	KIF20A	NDC1	CDC26	CDC27	SEC13	SKP2	NUP133	ANAPC7	H2AFZ	UBE2E1	H2AFX	H2AFV	CCNA2	MASTL	CCNA1	HIST2H2BE	CCNE2	CCNE1	GORASP2	MCM3	HIST4H4	MCM4	NUP50	ANAPC4	CNEP1R1	MCM5	GORASP1	ANAPC5	NUP54	MCM6	MCPH1	TUBA4B	ANAPC1	HIST1H2BN	MCM2	HIST1H2BM	ANAPC2	RAB1A	ANAPC15	HIST1H2BO	ANAPC16	HIST1H2BJ	ANAPC10	HIST1H2BI	ANAPC11	HIST1H2BL	ORC5	RAB1B	USO1	ORC4	TUBAL3	FZR1	HIST1H2BK	ORC6	PPP2CA	KIF18A	ORC1	HIST2H4A	ORC3	PPP2CB	ORC2	HIST2H4B	CDT1	MAPK1	UBE2C	NUP43	CDC6	RAE1	RANBP2	UBE2S	CDC16	PPP2R2D	CDK2	TUBA8	HIST3H3	WRAP53	NUP35	NCAPD3	CLIP1	NUPL2	NUP37	KIF23	DYNLL2	KIF2A	KIF2C	KIF2B	HSP90AB1	PSMD8	PSMD9	CDC45	PSMD6	GINS1	PSMD7	GINS2	PSMD4	GINS3	PSMD5	DYNC1I1	GINS4	PSMD2	PSMD3	PSMD1	E2F1	PSMA5	CENPE	PSMA6	PSMA3	BABAM1	PSMA4	HERC2	PSMA1	UIMC1	PSMA2	WHSC1	PSME3	PSME4	RNF168	PSME1	RNF8	PSME2	BRCC3	TP53BP1	PSMD10	PSMB11	PSMD12	PSMD11	TOP2A	PSMD14	LIN54	NIPBL	PSMD13	LIN37	BRE	MAU2	HJURP	MAX	FAM175A	PSMB10	RUVBL2	LIN9	PSMA7	OIP5	MYBL2	STRA13	E2F5	LYN	LIN52	PSMA8	SHQ1	PIF1	PSMB6	DYRK1A	TERT	PSMB7	UBE2N	PSMB4	RSF1	PSMB5	MIS18BP1	PSMB2	ATRX	PSMB3	CENPW	PSMB1	E2F2	MIS18A	PSMF1	SHFM1	PSMB8	E2F6	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	IST1	SPAST	CC2D1B	SUMO1	UBE2I	SYCP2	E2F3	SYCP1	SYNE2	FOXM1	SYNE1	PKMYT1	CKS1B	SUN2	SUN1	TEX12	SMC1B	SYCE3	SYCE2	SYCE1	REC8	STAG3	SYCP3	CCND3	AKT2	AKT3	AKT1	GSK3B	CCND1	CDK4	RRM2	TP53	TYMS	CDC7	ABL1	CDC25B	CDKN2D	CDKN2B	CDKN2C	MYC	TK1	RAD51C	BRIP1	EXO1	HDAC1	PRIM2	TOPBP1	ATRIP	DSCC1	BARD1	PRIM1	RMI2	CHTF18	RMI1	WRN	HUS1	CHTF8	OBFC1	CTC1	CABLES1	POLA1	RAD17	POLA2	RAD1	WEE1	TEN1	RAD9B	DNA2	RHNO1	ATR	RAD9A	CDC14A	FBXO5	RFWD2	ATM	GMNN	MCM10	DBF4	RPA4	YWHAQ	SFN	CDK6	CDKN2A	YWHAH	LBR	TFDP1	TFDP2	TINF2	TERF1	TERF2	POT1	TERF2IP	ACD	PPP2R3B	ESPL1	KAT5	CDKN1C	ANKRD28	CEP57	YWHAE	CETN2	CEP164	CCP110	PPP1CB	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	BTRC	NINL	CEP290	YWHAG	RAB8A	CDK5RAP2	SKP1	OFD1	HSP90AA1	BORA	PPP1R12A	CEP135	FBXW11	TUBB	CEP131	HAUS4	PPP6C	HAUS3	CSNK1D	HAUS6	PPP6R3	HAUS5	
CALMODULIN INDUCED EVENTS%REACTOME%R-HSA-111933.1	Calmodulin induced events	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	CAMK2G	CREB1	ADCY5	PRKCA	PRKCG	PDE1C	PDE1B	PDE1A	ADRBK1	CAMKK1	PRKCD	CAMKK2	PRKAR2B	PRKACG	PRKACB	KPNA2	NBEA	CAMK4	ADCY9	PRKAR1B	PRKAR1A	PRKX	CAMK2A	PRKAR2A	PRKACA	CAMK2B	ADCY4	CAMK2D	ADCY3	
DEFECTIVE ABCC9 CAUSES CMD10, ATFB12 AND CANTU SYNDROME%REACTOME%R-HSA-5678420.2	Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome	KCNJ11	ABCC9	
INTERFERON GAMMA SIGNALING%REACTOME%R-HSA-877300.3	Interferon gamma signaling	NCAM1	CAMK2G	ICAM1	JAK1	PTPN11	IRF3	IRF7	VCAM1	PRKCD	IFI30	TRIM29	TRIM25	TRIM26	HLA-A	B2M	TRIM21	FCGR1A	TRIM22	GBP6	GBP5	GBP7	IRF1	HLA-B	IRF2	SUMO1	HLA-C	HLA-F	HLA-G	CD44	JAK2	HLA-E	MT2A	TRIM17	HLA-DPA1	TRIM14	TRIM10	HLA-DQB2	HLA-DQB1	TRIM8	TRIM6	TRIM5	TRIM2	HLA-DQA2	TRIM3	HLA-DQA1	SP100	HLA-DRB5	HLA-DRB4	PTAFR	HLA-DPB1	HLA-DRA	HLA-DRB3	MID1	HLA-DRB1	SOCS3	CIITA	IFNG	IFNGR1	IFNGR2	OASL	PTPN6	TRIM68	PIAS1	TRIM62	OAS1	IRF4	OAS2	OAS3	PTPN1	IRF8	IRF5	IRF6	IRF9	PML	TRIM46	TRIM48	GBP2	GBP1	FCGR1B	GBP4	TRIM45	GBP3	CAMK2A	SOCS1	TRIM35	TRIM38	TRIM31	TRIM34	CAMK2B	CAMK2D	
FGFR4 MUTANT RECEPTOR ACTIVATION%REACTOME DATABASE ID RELEASE 74%1839128	FGFR4 mutant receptor activation	FGFR4	
REGULATION OF RUNX3 EXPRESSION AND ACTIVITY%REACTOME DATABASE ID RELEASE 74%8941858	Regulation of RUNX3 expression and activity	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	CBFB	PSME3	PSME1	PSME2	PSMD10	MDM2	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	RUNX3	PSMC4	PSMC1	PSMC2	SRC	SMURF2	SMURF1	TGFB1	CDKN2A	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	EP300	PSMD1	PSMA5	
MATURATION OF SPIKE PROTEIN%REACTOME%R-HSA-9683686.2	Maturation of spike protein	MOGS	PRKCSH	GANAB	MGAT1	CANX	
PLUS-STRAND DNA SYNTHESIS%REACTOME DATABASE ID RELEASE 74%164525	Plus-strand DNA synthesis	PPIA	
HH MUTANTS THAT DON'T UNDERGO AUTOCATALYTIC PROCESSING ARE DEGRADED BY ERAD%REACTOME%R-HSA-5362768.1	Hh mutants that don't undergo autocatalytic processing are degraded by ERAD	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	VCP	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	SEL1L	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	SYVN1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	DERL2	ERLEC1	OS9	SHH	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
CONJUGATION OF SALICYLATE WITH GLYCINE%REACTOME DATABASE ID RELEASE 74%177128	Conjugation of salicylate with glycine	ACSM2B	GLYATL3	GLYATL2	GLYATL1	ACSM2A	ACSM5	ACSM4	GLYAT	
GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR (GG-NER)%REACTOME DATABASE ID RELEASE 74%5696399	Global Genome Nucleotide Excision Repair (GG-NER)	POLK	XRCC1	LIG3	RUVBL1	NFRKB	INO80C	INO80B	UBA52	INO80E	INO80D	INO80	ACTR5	COPS7B	ACTR8	COPS7A	SUMO3	SUMO2	TFPT	UBE2N	PIAS3	UBB	MCRS1	UBC	ACTL6A	RPS27A	XPC	USP45	RAD23A	RAD23B	RPA1	RPA2	PARP1	RPA3	SUMO1	ACTB	UBE2I	ERCC4	GPS1	ERCC1	YY1	PIAS1	UBE2V2	CCNH	XPA	PARP2	CHD1L	CUL4A	DDB1	ERCC5	CUL4B	CETN2	DDB2	RBX1	RFC5	RFC3	PCNA	RFC4	GTF2H1	RFC1	GTF2H2	COPS4	LIG1	GTF2H3	COPS3	RFC2	GTF2H4	COPS6	POLE4	POLD3	GTF2H5	COPS5	POLD4	CDK7	COPS2	POLE2	POLD1	ERCC3	RNF111	POLE3	POLD2	COPS8	POLE	ERCC2	MNAT1	
T41 MUTANTS OF BETA-CATENIN AREN'T PHOSPHORYLATED%REACTOME DATABASE ID RELEASE 74%5358752	T41 mutants of beta-catenin aren't phosphorylated	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	CTNNB1	PPP2R1B	AMER1	AXIN1	APC	
RIBOSOMAL SCANNING AND START CODON RECOGNITION%REACTOME DATABASE ID RELEASE 74%72702	Ribosomal scanning and start codon recognition	RPS26	RPS25	RPS28	EIF5	RPS27	RPS29	RPS20	RPS21	RPS24	RPS23	RPS4X	RPS3A	RPS27L	RPS15A	EIF2S2	RPS3	EIF2S1	EIF4H	RPS27A	EIF2S3	RPS2	EIF4E	EIF4B	EIF3M	EIF3K	EIF3L	EIF3I	EIF3J	EIF4G1	EIF3G	EIF3H	EIF3E	EIF3F	FAU	EIF3C	EIF3D	EIF3A	EIF3B	EIF4A2	EIF4A1	RPS15	RPS14	RPS17	RPS16	RPS19	RPS18	RPS11	RPS10	RPS13	RPS12	RPS9	RPS7	EIF1AX	RPS8	RPS5	RPS6	RPSA	RPS4Y2	RPS4Y1	
REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION%REACTOME%R-HSA-9617629.1	Regulation of FOXO transcriptional activity by acetylation	KAT2B	TXNIP	FOXO4	TXN	FOXO3	FOXO1	CREBBP	EP300	SIRT1	SIRT3	
SODIUM-COUPLED PHOSPHATE COTRANSPORTERS%REACTOME%R-HSA-427652.1	Sodium-coupled phosphate cotransporters	SLC20A2	SLC34A1	SLC20A1	SLC34A2	SLC34A3	
ANTIVIRAL MECHANISM BY IFN-STIMULATED GENES%REACTOME DATABASE ID RELEASE 74%1169410	Antiviral mechanism by IFN-stimulated genes	MAPK3	NUP62	JAK1	PIN1	IRF3	NDC1	SEC13	NUP133	UBA52	UBE2E1	NUP50	PLCG1	NUP54	UBE2N	UBB	UBC	KPNA7	KPNA4	KPNA5	KPNA2	RPS27A	KPNA3	UBE2L6	KPNA1	IFIT1	KPNB1	EIF4E	NUP43	EIF2AK2	HERC5	RAE1	ISG15	RANBP2	TRIM25	NUP35	NUPL2	EIF4G1	NUP37	NUP107	NUP188	PDE12	NUP214	ARIH1	NUP210	RNASEL	FLNA	FLNB	NUP93	UBA7	EIF4A2	EIF4A1	EIF4G3	EIF4G2	EIF4E3	OASL	DDX58	PPM1B	NUP205	OAS1	POM121	OAS2	OAS3	EIF4A3	AAAS	USP41	NUP160	EIF4E2	NUP85	TPR	USP18	NUP88	NUP155	MX2	MX1	STAT1	ABCE1	NUP153	NEDD4	
OTHER INTERLEUKIN SIGNALING%REACTOME DATABASE ID RELEASE 74%449836	Other interleukin signaling	CSF1	STXBP2	CD4	TXLNA	IFNL1	STX4	JAK1	IL16	TYK2	PTPRZ1	CSF3R	IL32	SDC1	IL34	STX3	STX1A	CASP3	SNAP25	CSF1R	IL10RB	PRTN3	VAMP2	IFNLR1	CSF3	
ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION%REACTOME%R-HSA-450302.2	activated TAK1 mediates p38 MAPK activation	RIPK2	MAPKAPK3	TRAF6	MAPK14	MAPK11	IRAK1	UBE2V1	MAP2K6	UBE2N	TAB3	TAB2	NOD1	TAB1	NOD2	MAPKAPK2	IKBKG	MAP3K7	MAP2K3	IRAK2	
DEFECTIVE SLC1A1 IS IMPLICATED IN SCHIZOPHRENIA 18 (SCZD18) AND DICARBOXYLIC AMINOACIDURIA (DCBXA)%REACTOME DATABASE ID RELEASE 74%5619067	Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA)	SLC1A1	
THE ACTIVATION OF ARYLSULFATASES%REACTOME%R-HSA-1663150.1	The activation of arylsulfatases	ARSD	ARSE	ARSA	SUMF2	SUMF1	ARSB	STS	ARSJ	ARSK	ARSH	ARSI	ARSF	ARSG	
LOSS OF FUNCTION OF TGFBR1 IN CANCER%REACTOME%R-HSA-3656534.1	Loss of Function of TGFBR1 in Cancer	SMAD2	SMAD3	TGFB1	TGFBR1	TGFBR2	FKBP1A	
ECM PROTEOGLYCANS%REACTOME DATABASE ID RELEASE 74%3000178	ECM proteoglycans	ITGB5	LRP4	TNC	LAMB2	NCAM1	LAMA2	LAMA1	COMP	IBSP	ITGAX	COL9A1	COL9A3	ITGB6	COL9A2	ITGA8	LAMC1	ITGA7	VTN	SPARC	NCAN	BGN	VCAN	ITGA2B	TGFB2	DCN	TGFB3	LUM	LAMA5	FMOD	LAMA3	LAMB1	AGRN	PTPRS	TGFB1	ITGB1	DAG1	ITGB3	DMP1	ITGAV	MUSK	ITGA2	MATN1	SERPINE1	MATN4	MATN3	HSPG2	TNXB	BCAN	DSPP	TNN	TNR	ITGA9	HAPLN1	ASPN	LAMA4	
ACTIVATION OF RRNA EXPRESSION BY ERCC6 (CSB) AND EHMT2 (G9A)%REACTOME DATABASE ID RELEASE 74%427389	Activation of rRNA Expression by ERCC6 (CSB) and EHMT2 (G9a)	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HDAC2	HDAC1	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	CBX3	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	EHMT2	H2AFB1	CHD4	CHD3	HIST1H3J	TTF1	MTA1	HIST1H3A	RBBP4	HIST1H3F	HIST1H3G	HIST1H3H	RBBP7	HIST1H3I	MTA2	HIST1H3B	MTA3	HIST1H3C	HIST1H3D	MBD3	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	GATAD2B	GATAD2A	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	ERCC6	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES%REACTOME DATABASE ID RELEASE 74%5579029	Metabolic disorders of biological oxidation enzymes	SLC35D1	CYP1B1	AHCY	TPMT	CYP17A1	TBXAS1	GGT1	MAT1A	UGT1A4	CYP2U1	CYP27A1	CYP11A1	CYP19A1	POMC	CYP27B1	MC2R	ACY1	CYP11B2	CYP11B1	CYP2R1	CYP21A2	CYP4F22	CYP24A1	FDX1	FDXR	CYP7B1	FDX1L	GCLC	MAOA	GCLM	OPLAH	FMO3	CYP26B1	GSS	UGT1A1	CYP26C1	
VLDLR INTERNALISATION AND DEGRADATION%REACTOME DATABASE ID RELEASE 74%8866427	VLDLR internalisation and degradation	AP2A2	AP2M1	NR1H2	MYLIP	CLTC	PCSK9	NR1H3	CLTA	AP2A1	AP2B1	VLDLR	AP2S1	
RESPONSE OF EIF2AK4 (GCN2) TO AMINO ACID DEFICIENCY%REACTOME%R-HSA-9633012.2	Response of EIF2AK4 (GCN2) to amino acid deficiency	UBA52	EIF2S2	EIF2S1	EIF2S3	RPS27A	CEBPB	CEBPG	RPL4	RPL5	ASNS	RPL30	DDIT3	RPL3	RPL32	ATF3	RPL31	ATF4	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	EIF2AK4	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	IMPACT	RPL12	RPL11	GCN1L1	RPL36A	RPS27L	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	ATF2	TRIB3	
PROTON-COUPLED MONOCARBOXYLATE TRANSPORT%REACTOME DATABASE ID RELEASE 74%433692	Proton-coupled monocarboxylate transport	SLC16A1	SLC16A7	EMB	BSG	SLC16A8	SLC16A3	
INTERLEUKIN-1 SIGNALING%REACTOME%R-HSA-9020702.2	Interleukin-1 signaling	SQSTM1	RIPK2	IRAK3	IRAK4	UBA52	PELI1	CUL1	UBB	PELI3	PELI2	NOD1	NOD2	UBC	RPS27A	S100B	TNIP2	SAA1	MAP2K1	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	IKBKG	MAP3K7	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	TRAF6	PSMB11	PSMD12	PSMD11	PSMD14	UBE2V1	PSMD13	PSMB10	PSMA7	RELA	PSMA8	PSMB6	UBE2N	PSMB7	TAB3	PSMB4	TAB2	PSMB5	TAB1	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	IRAK2	PSMB8	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	NFKBIB	IL1A	IL1B	IL1RN	IL1R2	IL1R1	TOLLIP	MAP3K3	APP	MAP2K4	RBX1	MAP3K8	AGER	BTRC	IRAK1	S100A12	MAP2K6	SKP1	NFKB2	MYD88	FBXW11	HMGB1	NKIRAS1	NKIRAS2	
REGULATION OF INSULIN SECRETION%REACTOME%R-HSA-422356.4	Regulation of insulin secretion	CACNB2	CACNB3	ADCY8	ADCY6	ADCY5	KCNB1	GNG12	GNG11	GNG13	GCG	KCNS3	GNB2	GNB1	CACNA1A	CHRM3	GNB4	CACNA1E	GNB3	GNB5	STX1A	SNAP25	PRKAR2B	AKAP5	SLC2A1	AHCYL1	SYT5	ADRA2C	MARCKS	ADRA2A	KCNJ11	VAMP2	GNAI1	GNAI2	PRKCA	ACSL4	FFAR1	ACSL3	STXBP1	INS	RAP1A	GLP1R	GNA14	GNA15	KCNG2	GNA11	GNAQ	ABCC8	RAPGEF3	PRKACG	PRKACB	RAPGEF4	GNGT1	SLC2A2	GNGT2	CACNA1D	PRKAR1B	CACNA1C	PRKAR1A	PLCB3	PLCB1	PLCB2	PRKACA	PRKAR2A	CACNA2D2	ITPR1	ITPR2	ITPR3	KCNC2	GNAS	GNG3	IQGAP1	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	CD36	
AGMATINE BIOSYNTHESIS%REACTOME%R-HSA-351143.1	Agmatine biosynthesis	AGMAT	AZIN2	
WNT LIGAND BIOGENESIS AND TRAFFICKING%REACTOME%R-HSA-3238698.1	WNT ligand biogenesis and trafficking	WNT10A	WNT5B	WNT3A	WNT7B	WNT7A	WNT2B	WNT9B	PORCN	WNT9A	WNT16	WNT5A	WLS	WNT8A	WNT8B	SNX3	VPS29	WNT11	VPS35	WNT6	TMED5	WNT1	WNT2	VPS26A	WNT3	WNT4	WNT10B	
RHO GTPASES REGULATE CFTR TRAFFICKING%REACTOME DATABASE ID RELEASE 74%5627083	RHO GTPases regulate CFTR trafficking	GOPC	CFTR	RHOQ	
BIOSYNTHESIS OF THE N-GLYCAN PRECURSOR (DOLICHOL LIPID-LINKED OLIGOSACCHARIDE, LLO) AND TRANSFER TO A NASCENT PROTEIN%REACTOME%R-HSA-446193.1	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	PMM2	DOLK	NAGK	GLB1	DOLPP1	ST3GAL4	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	ALG10B	ST6GALNAC3	ST6GALNAC4	GFPT1	DPAGT1	ALG8	ALG9	ALG6	ALG14	ALG3	ALG13	ALG12	ALG1	MPDU1	RFT1	DPM1	DPM2	SLC35A1	DPM3	SLC35C1	ST6GALNAC1	CMAS	MPI	GMPPB	NANP	FPGT	GMPPA	PGM3	ALG2	GNPNAT1	NANS	ALG11	NUDT14	ST6GAL2	ALG5	RENBP	ALG10	DHDDS	MVD	ST6GALNAC5	ST6GALNAC6	GNE	TSTA3	UAP1	NPL	FUOM	NEU2	NEU3	NEU4	GMDS	AMDHD2	NEU1	SLC17A5	ST8SIA4	ST8SIA5	ST3GAL5	ST3GAL6	ST8SIA6	FUK	CTSA	NUS1	PMM1	ST8SIA1	ST8SIA2	GFPT2	SRD5A3	ST6GALNAC2	ST8SIA3	
BIOSYNTHESIS OF DPAN-3 SPMS%REACTOME DATABASE ID RELEASE 74%9025094	Biosynthesis of DPAn-3 SPMs	PTGS2	ALOX15	ALOX12	ALOX5	
G ALPHA (S) SIGNALLING EVENTS%REACTOME%R-HSA-418555.7	G alpha (s) signalling events	OR11A1	OR8A1	OR8I2	OR52N1	OR52N5	OR52N4	OR52N2	OR5D18	OR10W1	OR2A42	OR5D16	OR5D14	OR5D13	OR8H3	OR8H2	OR8H1	OR52M1	OR10V1	OR4C12	OR6C6	OR4C11	OR6C4	OR6C3	OR4C16	OR8G5	OR6C2	OR4C15	OR5AK2	OR6C1	OR4C13	OR8G1	OR10T2	OR52L1	OR6B3	OR6B2	OR6B1	OR2A25	PDE2A	OR10S1	OR52K2	OR52K1	PDE3A	OR2A12	OR6A2	OR2A14	OR2A1	OR4E2	OR4D9	OR5AP2	OR5B12	OR4D6	OR4D5	OR5B17	OR4D2	OR4D1	OR10Z1	OR52R1	OR4C6	OR4C5	OR4A15	OR4C3	OR4A16	OR8K5	OR8K3	OR8K1	OR5AN1	OR4B1	OR4C46	OR6F1	OR8J3	OR8J1	OR10X1	OR4A5	OR6M1	OR2T12	OR2T10	OR2T11	OR5H15	OR5H14	PDE8B	PDE8A	OR2D3	OR2D2	OR52E4	OR52E2	OR5AC2	OR52E8	OR52E6	OR52E5	OR2C3	OR6K6	OR2C1	OR6K3	OR6K2	OR52D1	OR2B6	OR4F6	OR2B3	OR4F5	OR2B2	OR10K2	OR4F4	OR4F3	OR10K1	OR6J1	OR2A7	OR2A5	OR2A4	OR2A2	OR52J3	OR4M2	OR4M1	OR10R2	OR6Q1	OR8U1	OR52I2	OR52I1	OR2H2	OR2H1	OR4L1	OR6P1	OR10Q1	OR2G6	OR52H1	OR2G3	OR4K5	SRC	OR2G2	OR4K2	OR4K1	OR10P1	OR2T34	OR8S1	OR2T35	OR2T33	PDE11A	AVP	OR2T27	OR2F2	OR2F1	OR2T29	OR6N2	OR6N1	PDE10A	PDE7B	ADCY9	PDE7A	GNAS	ADCY4	ADCY3	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY5	PDE3B	ARRB1	ARRB2	GNAL	GLP1R	VIPR1	VIPR2	SCT	ADM	PTH1R	CYSLTR2	GLP2R	PTH2R	GIP	ADCYAP1	CRH	IAPP	CALCA	RAMP2	ADCYAP1R1	RAMP3	CALCRL	CALCB	GIPR	PTH	PTH2	PTHLH	CRHR1	OR2M7	GHRHR	OR2M5	OR2M4	CALCR	OR2M3	OR4K17	OR2M2	OR4Q3	OR2L8	OR2L5	OR2L3	OR4P4	OR2L2	OR10AD1	OR6T1	OR4K15	OR4K14	SCTR	OR4K13	OR2K2	GCG	OR6S1	ADM2	GHRH	VIP	OR10D3	RAMP1	OR8B12	OR14K1	OR4N5	OR2J3	OR4N4	OR2J2	OR2J1	OR4N2	OR10C1	OR10J1	OR10J3	OR10J5	OR6Y1	OR52B2	OR52B6	OR6X1	OR52A1	OR52A5	OR10H1	OR10H3	OR10H2	OR10H5	OR10H4	OR4S2	OR4S1	OR10G2	OR14A16	OR10G4	OR10G3	OR6V1	OR10G6	OR10G8	OR10G7	OR10G9	OR14C36	OR2T8	OR2T7	OR2T6	OR2T5	OR2T4	OR2T3	OR2T2	OR2T1	OR4X2	OR4X1	OR9A4	OR51T1	OR9A2	OR2S2	OR51S1	OR7E24	OR7A10	OR14J1	OR2Y1	OR56B1	OR56B4	OR7A17	OR14I1	OR10A7	ADORA2A	OR56A5	OR7A5	OR10A2	OR56A4	OR10A4	OR10A3	OR56A3	OR10A6	GNGT1	OR10A5	OR56A1	GNGT2	OR2W3	OR2W1	OR12D3	OR12D2	OR51V1	OR2V2	OR2V1	OR7G2	OR7G1	OR9K2	OR51L1	GNG3	GNG10	OR5B3	OR5B2	GNG2	GNG5	GNG4	GNG7	GNG8	OR2AT4	OR5A2	OR5A1	OR9I1	GNG12	GNG11	OR51J1	GNG13	OR7D4	OR7D2	OR51I2	GNB2	GNB1	OR51I1	GNB4	PDE1B	GNB3	PDE1A	OR4D11	ADRBK1	GNB5	OR4D10	OR2Z1	OR9G4	OR7C2	OR7C1	OR9G1	OR51Q1	OR5F1	OR3A3	OR14A2	OR3A2	OR3A1	OR51M1	OR5C1	OR7G3	OR1C1	OR5K4	OR5K3	OR5K2	OR51D1	OR5K1	OR1B1	OR5J2	OR1A2	OR1A1	OR51B2	OR5I1	OR9Q2	OR9Q1	OR2AK2	GRK5	GRK6	OR51B6	OR51B5	OR51B4	OR5H6	OR5H2	OR5H1	OR2AJ1	OR51A4	OR51A2	OR51A7	RTP4	RTP5	RTP2	OR51H1	RTP3	RTP1	OR1G1	OR10AG1	OR51G2	OR51G1	OR1F1	OR2AP1	OR2B11	OR51F2	OR51F1	OR5M9	OR5M8	OR1E2	OR1E1	OR5M3	OR5M1	OR4F29	OR4F21	OR51E1	OR1D5	OR1D2	OR51E2	OR5L2	OR5L1	OR4F17	OR4F16	OR4F15	OR11H2	OR11H1	OR11H4	RXFP1	ADRB1	OR1K1	RXFP2	GPR176	ADRB2	GNAT3	HTR4	OR2AE1	OR11H6	PTGDR	HTR6	HTR7	OR1J4	LHB	OR11G2	HRH2	OR1J2	OR1J1	DRD1	CRHR2	OR5R1	MC2R	CGA	OR13J1	GPR15	OR1I1	DRD5	MC1R	TAAR8	OR5M11	OR5M10	GPR27	TAAR9	GPR25	GPR20	TAAR6	MC4R	OR5P3	GPR39	OR5P2	FSHB	GPR32	TAAR5	TAAR2	OR11L1	GPBAR1	MC3R	OR5W2	TAAR1	FSHR	NPSR1	OR1N2	ADRB3	PTGER4	OR1N1	GPR45	OR5V1	PTGER2	GNAI3	OR1M1	GNAI1	OR2AG1	GNAI2	OR2AG2	NPS	GPR150	GPHA2	ADRBK2	P2RY11	OR1L8	MC5R	OR1L6	GPHB5	OR1L4	OR1L3	OR1L1	LHCGR	OR5T3	OR5T2	OR5T1	GNAZ	OR52W1	GPR83	OR1S2	GPR84	OR1S1	OR13D1	OR5AS1	OR13C9	OR13C8	RLN2	RLN3	OR2L13	OR13C3	OR13C2	INSL3	OR13C5	TSHB	OR13C4	PTGIR	OR5AR1	AVPR2	OR1Q1	ADORA2B	OR4A47	PDE4A	TSHR	OR5B21	PDE4D	REEP1	PDE4C	POMC	REEP5	REEP4	REEP3	REEP2	REEP6	OR13A1	OR13H1	OR8D4	OR8D2	OR8D1	OR6C70	OR6C76	OR6C75	OR6C74	OR13G1	OR6C65	OR8B8	OR8B4	OR6C68	OR13F1	OR8B3	OR8B2	OR5AU1	
THE NLRP1 INFLAMMASOME%REACTOME%R-HSA-844455.1	The NLRP1 inflammasome	BCL2	NLRP1	BCL2L1	
ACTIVATION OF APC C AND APC C:CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS%REACTOME%R-HSA-176814.2	Activation of APC C and APC C:Cdc20 mediated degradation of mitotic proteins	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	UBE2D1	PSME1	CDC23	PSME2	CDC26	CDC27	PSMD10	PSMB11	ANAPC7	UBA52	PSMD12	UBE2E1	PSMD11	CCNA2	PSMD14	CCNA1	PSMD13	PSMB10	PSMA7	ANAPC4	PSMA8	ANAPC5	PSMB6	PSMB7	CCNB1	ANAPC1	PSMB4	UBB	PSMB5	ANAPC2	PSMB2	ANAPC15	PSMB3	ANAPC16	UBC	PSMB1	ANAPC10	PSMF1	ANAPC11	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	UBE2C	PSMC1	PSMC2	UBE2S	PLK1	CDC16	CDK1	PTTG1	BUB1B	CDC20	BUB3	MAD2L1	NEK2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
DEFECTIVE FACTOR IX CAUSES THROMBOPHILIA%REACTOME%R-HSA-9672383.1	Defective factor IX causes thrombophilia	F8	F10	F9	
FBXL7 DOWN-REGULATES AURKA DURING MITOTIC ENTRY AND IN EARLY MITOSIS%REACTOME%R-HSA-8854050.2	FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	FBXL18	PSMD13	PSMB10	PSMA7	CUL1	PSMA8	AURKA	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	FBXL7	RBX1	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
TFAP2 (AP-2) FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS%REACTOME DATABASE ID RELEASE 74%8866910	TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ERBB2	TGFA	EGFR	ATAD2	YY1	CGA	VEGFA	ESR1	TFAP2A	KIT	TFAP2B	TFAP2C	
TRAIL SIGNALING%REACTOME DATABASE ID RELEASE 74%75158	TRAIL signaling	TNFRSF10D	TNFRSF10B	TNFRSF10A	CASP8	TNFSF10	CFLAR	CASP10	FADD	
EVENTS ASSOCIATED WITH PHAGOCYTOLYTIC ACTIVITY OF PMN CELLS%REACTOME DATABASE ID RELEASE 74%8941413	Events associated with phagocytolytic activity of PMN cells	LPO	MPO	
SIGNALING BY ERBB2 KD MUTANTS%REACTOME DATABASE ID RELEASE 74%9664565	Signaling by ERBB2 KD Mutants	ERBB2IP	EREG	SHC1	BTC	EGF	GAB1	NRG1	ERBB2	EGFR	NRG2	NRAS	HSP90AA1	CDC37	NRG3	PLCG1	SOS1	NRG4	HRAS	PIK3R1	PIK3CA	HBEGF	
PROTEIN UBIQUITINATION%REACTOME%R-HSA-8852135.2	Protein ubiquitination	UBE2D2	UBE2D1	CDC34	VCP	UBA52	UBE2E1	BCL10	UCHL3	UBE2N	HIST1H2BN	UBB	HIST1H2BM	HIST1H2BO	HIST1H2BJ	UBC	HIST1H2BI	HIST1H2BL	RPS27A	HIST1H2BK	UBE2C	UBE2S	UBE2G1	HLA-A	USP5	UBE2G2	DERL1	USP9X	OTULIN	UBE2Z	UBA6	UBE2Q2	UBE2H	HIST1H2BF	HIST1H2BE	HIST1H2BH	UBE2W	CDC73	UBE2R2	HIST1H2BG	UBE2L3	RNF152	HIST1H2BB	UBA1	SHPRH	UBE2K	PEX2	HIST1H2BA	RNF40	RNF144A	HIST1H2BD	WAC	HIST1H2BC	UBE2E3	UBE2V2	VIMP	PRKDC	CTR9	WDR61	RTF1	UBE2D3	UBE2J2	RRAGA	HLTF	TMEM129	LEO1	RNF20	UBE2B	PEX10	UBE2A	PEX12	PEX13	PEX14	RNF181	PAF1	PCNA	RAD18	USP7	UBE2T	
MITOCHONDRIAL TRANSCRIPTION TERMINATION%REACTOME%R-HSA-163316.2	Mitochondrial transcription termination	MTERF1	
DEFECTIVE SLC35C1 CAUSES CONGENITAL DISORDER OF GLYCOSYLATION 2C (CDG2C)%REACTOME%R-HSA-5619078.1	Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)	SLC35C1	
NEGATIVE REGULATION OF THE PI3K AKT NETWORK%REACTOME DATABASE ID RELEASE 74%199418	Negative regulation of the PI3K AKT network	MAPK3	AREG	IRAK4	PTPN11	PTEN	TRAF6	PIP5K1C	EGF	GAB1	EGFR	KIT	HBEGF	INSR	PPP2CA	PPP2CB	EPGN	MAPK1	KLB	PIK3CD	RAC1	IRS2	FGF1	PIK3CB	FGF2	FGF3	FGF4	VAV1	FGF6	FGF7	FGF9	IL1RL1	PPP2R1B	PDGFRB	IL33	ESR1	PDGFRA	IER3	PIP5K1A	HGF	PIP5K1B	ESR2	STRN	PHLPP2	PHLPP1	IRS1	SRC	TRAT1	PIK3AP1	PIP4K2A	CD19	PIP4K2B	PIP4K2C	INS	FGF20	FGF23	FGF22	ERBB2	FGF16	CD86	CD80	PIK3R3	FGF19	PIK3R2	FGF18	RAC2	PIK3R1	FGFR4	PIK3CA	LCK	AKT2	FGF10	AKT3	CD28	THEM4	AKT1	TRIB3	FYN	PPP2R1A	RHOG	PPP2R5E	FRS2	PPP2R5B	EREG	IRAK1	PPP2R5A	BTC	PPP2R5D	NRG1	PPP2R5C	PDGFB	TGFA	NRG2	MYD88	NRG3	NRG4	MET	
DEFECTIVE DPM2 CAUSES DPM2-CDG (CDG-1U)%REACTOME%R-HSA-4719377.1	Defective DPM2 causes DPM2-CDG (CDG-1u)	DPM1	DPM2	DPM3	
ACTIVATION OF GENE EXPRESSION BY SREBF (SREBP)%REACTOME%R-HSA-2426168.2	Activation of gene expression by SREBF (SREBP)	RXRA	IDI1	FDPS	TBL1XR1	MVK	GGPS1	SP1	ACACB	NFYA	TGS1	NFYB	CYP51A1	NFYC	LSS	TM7SF2	ELOVL6	SQLE	PMVK	FASN	CARM1	TBL1X	ACACA	MVD	FDFT1	GPAM	MED1	SC5D	DHCR7	HMGCS1	MTF1	HELZ2	NCOA1	PPARA	SCD	NCOA2	CHD9	NCOA6	CREBBP	SMARCD3	SREBF2	
CREB PHOSPHORYLATION%REACTOME%R-HSA-199920.1	CREB phosphorylation	RPS6KA1	CREB1	ATF1	MAPKAPK2	RPS6KA3	RPS6KA5	RPS6KA2	
CELLULAR RESPONSE TO HYPOXIA%REACTOME DATABASE ID RELEASE 74%1234174	Cellular response to hypoxia	ARNT	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	UBE2D2	PSME3	CUL2	PSME4	UBE2D1	PSME1	EGLN1	PSME2	EGLN3	AJUBA	PSMD10	EGLN2	PSMB11	WTIP	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	HIF1AN	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	TCEB2	TCEB1	PSMF1	EPAS1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	LIMD1	VEGFA	PSMC1	PSMC2	EPO	HIGD1A	CA9	VHL	CITED2	HIF3A	UBE2D3	RBX1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	CREBBP	PSMD3	EP300	HIF1A	PSMD1	PSMA5	
CLEARANCE OF SERATONIN%REACTOME DATABASE ID RELEASE 74%380615	Clearance of seratonin	MAOA	ALDH2	SLC6A4	
RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION%REACTOME DATABASE ID RELEASE 74%8940973	RUNX2 regulates osteoblast differentiation	YAP1	ZNF521	MAPK3	CBFB	SRC	COL1A1	HDAC6	MAPK1	WWTR1	ABL1	YES1	UCMA	SP7	RB1	SATB2	AR	HEY1	GLI3	HEY2	BGLAP	HDAC3	HES1	MAF	
T(4;14) TRANSLOCATIONS OF FGFR3%REACTOME%R-HSA-2033515.1	t(4;14) translocations of FGFR3	FGFR3	
INTERLEUKIN-35 SIGNALLING%REACTOME%R-HSA-8984722.3	Interleukin-35 Signalling	STAT4	IL27RA	IL12A	IL6ST	JAK2	JAK1	IL12RB2	EBI3	TYK2	STAT1	STAT3	CANX	
MOLECULES ASSOCIATED WITH ELASTIC FIBRES%REACTOME DATABASE ID RELEASE 74%2129379	Molecules associated with elastic fibres	ITGB5	EFEMP2	EFEMP1	BMP7	GDF5	BMP4	MFAP5	MFAP4	MFAP1	ITGB8	MFAP3	MFAP2	ITGB6	ITGA8	TGFB1	ITGB1	VTN	ITGB3	BMP2	TGFB2	ITGAV	TGFB3	BMP10	LTBP4	FBLN1	LTBP2	LTBP3	FBLN2	LTBP1	FBLN5	
DISEASE%REACTOME%R-HSA-1643685.13	Disease	ABCA12	ABCG8	ABCG5	CFTR	VCP	ABCB6	ABCB4	SEL1L	ABCA3	ABCA4	ERLIN1	ERLIN2	RNF185	ABCD1	ABCC2	ABCC6	APOA1	ABCC9	DERL3	DERL1	DERL2	RNF5	ERLEC1	OS9	KCNJ11	STRN	TRAT1	PIK3AP1	DPM1	DPM2	DPM3	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	YWHAB	XPO1	CYFIP2	NCKAP1	MAPK14	CYFIP1	WIPF1	ARPC1B	WIPF2	ARPC1A	WIPF3	BRK1	WASL	ACTB	ACTG1	NCK1	ACTR3	VAV3	ACTR2	VAV2	MYH2	ELMO1	BTK	ELMO2	WAS	NCKIPSD	NCKAP1L	WASF1	WASF2	WASF3	MYO10	MYO5A	ARPC4	MYO9B	ARPC5	BAIAP2	MYO1C	ABI2	ARPC2	ARPC3	ABI1	PAH	SLC34A2	ALG2	ALG11	PRKACG	PRKACB	RBX1	ADCY9	PRKAR1B	PRKAR1A	PRKAR2A	GNAS	TSG101	VPS4B	VPS4A	MVB12B	MVB12A	ADCY4	VPS36	ADCY3	VTA1	ADCY2	VPS37C	ADCY1	VPS37D	AVPR1B	ADCY8	VPS37A	ADCY7	VPS37B	AVPR1A	ADCY6	STAM	ADCY5	SNF8	MMAB	CSNK1A1	HGS	HHAT	CHMP2B	CHMP2A	CHMP4C	CHMP4B	UBAP1	CHMP3	CHMP4A	CHMP6	CHMP7	STAM2	VPS25	VPS28	CHMP5	SLC5A1	RPIA	ENO1	HK1	ALDOB	PGK1	BTD	PPP1R3C	NHLRC1	HLCS	TCN2	CD320	SFTA3	GBE1	SFTPB	SFTPC	SFTPD	EPM2A	ACACA	G6PC3	HGSNAT	GIF	DCXR	PCCA	FEN1	PCCB	SFTPA2	GALNS	LIG1	PC	SFTPA1	CDKN1A	CDKN1B	CDC25A	MDM2	APP	ELK1	MAP2K4	NAGLU	GOLGA4	MAP2K7	JUN	CHST14	B3GALT6	NFKB2	EXT1	MYD88	EXT2	SGSH	CD36	GUSB	DYNC1LI1	IRAK4	DYNC1LI2	B4GALT7	TIRAP	CHST3	TLR1	CHSY1	TRAF3	TLR7	TLR10	TLR6	TLR5	HEY1	TLR3	HEY2	TLR2	UNC93B1	MAN2A1	MAPK8	ERBB2IP	ARF1	KANK1	DYNLL2	ACE2	TMPRSS2	SLC39A4	SLC5A2	SLC2A10	ABCB11	SLC16A1	RHAG	GALT	GALE	PGM1	GALK1	CUX1	FOXO6	FOXO4	GSK3A	DYNC1I1	GALNT1	LMNA	GFPT1	SYVN1	TRIM28	MPI	G6PC	GNGT1	DHDDS	GNGT2	GNE	WNT5A	CAMK2A	ITPR1	ITPR2	NEU1	ITPR3	SLC17A5	GNG3	GNG10	GNG2	GNG5	GNG4	CTSA	GNG7	NUS1	GNG8	CYP26B1	TCF7L2	CYP26C1	SRD5A3	PMM2	DOLK	FZD5	GLB1	FZD4	FZD6	FOXO1	GNG12	CYP17A1	GNG11	GNG13	MSH3	GNB2	GNB1	GNB4	GNB3	CTNNB1	GNB5	IDUA	HEXB	FOXO3	NCAN	HEXA	BGN	VCAN	TNKS2	HYAL1	TNKS	IDS	CSPG5	CSPG4	ARSB	ROCK1	ROCK2	PPIA	ERBB2	MYH9	BAD	ZMYM2	FGFR1OP2	TRIM24	MYO18A	LRRFIP1	BCR	BAG4	CPSF6	STAT1	STAT3	FGFR3	FGFR2	FGFR1	MAPK3	HDAC4	HDAC5	SHC1	HDAC8	EGF	GAB1	HDAC9	CBL	HDAC7	EGFR	NRAS	CDC37	PLCG1	SOS1	HRAS	HDAC10	HDAC11	KDR	ESR2	NR4A1	THBS1	SH3GL3	FIP1L1	CYP7B1	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	HEYL	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	MTRR	RPL3L	RPS26	AHCY	RPS25	TPMT	RPS28	RPS27	MTR	RPS29	RPL27A	MAT1A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RCC1	NMT1	NMT2	RPL13A	RPS3A	PDCD6IP	RNMT	RPL37A	RPL10	RANBP1	RNGTT	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	CD4	IRS1	SRC	NELFB	SMAD2	SMAD3	TGFB1	TGFBR1	TGFBR2	RAC2	NOS2	NEIL1	VPS33B	CORO1A	RAB7A	NOTCH2	MAML2	MAML1	PSEN2	RBPJ	DLL1	DLL4	APH1A	NEURL1B	APH1B	EP300	HES1	HES5	JAG2	PSENEN	JAG1	MIB2	MIB1	CREB1	NEURL1	MAML3	MAMLD1	GALNT12	MUCL1	MUC17	MUC5B	MUC3A	MUC5AC	MUC1	MUC7	MUC12	MUC13	MUC15	MUC20	MUC4	MUC21	MUC6	LTF	NCBP1	NCBP2	MCCC2	MCCC1	SLC22A5	IPO5	KPNA7	KPNA4	KPNA5	KPNA2	KPNA3	KPNA1	GTF2F1	GTF2F2	KPNB1	CPSF4	EIF2AK2	ISG15	CALR	GRSF1	CLTC	CLTA	PARP1	DNAJC3	CANX	PABPN1	RAN	MRC1	UBE2D1	CDC23	CDC26	CDC27	SKP2	ANAPC7	UBE2E1	CCNE2	CCNE1	ANAPC4	ANAPC5	EZH2	ANAPC1	ANAPC2	ANAPC15	ANAPC16	ANAPC10	ANAPC11	FZR1	UBE2C	UBE2S	CDC16	CDK2	AGRN	HSP90AB1	E2F1	CCNC	IGKV2-28	IGKV1-12	IGKV3D-20	IGKV2D-28	IGKV4-1	IGKV2D-30	STX1B	IGKV3-11	LYN	IGKV5-2	STX1A	XRCC6	XRCC5	SDC2	CHST6	CBX1	AP1G1	PACS1	AP1B1	AP1S2	AP1S1	AP1S3	HLA-A	B2M	AP1M2	SNW1	AP1M1	DPAGT1	ALG8	ALG9	ALG6	ALG14	ALG3	ALG13	ALG12	ALG1	MPDU1	RFT1	TRADD	LY96	TRAF2	FASLG	GPC1	TICAM1	CASP8	RIPK1	CD14	FADD	TLR4	CCND3	ITGB1	IL6R	UVRAG	SH3GL2	FN1	PARP16	PARP14	PARP10	PARP6	PARP4	PARP9	MMAA	PARP8	MUT	BECN1	CREBBP	EED	RAF1	PAK2	CTDP1	ELL	CCNT1	SUPT4H1	TCEB3	TCEB2	TCEB1	NELFA	NELFCD	TCEB3C	TCEB3CL	TCEB3B	NELFE	SUPT16H	MYC	SSRP1	SUPT5H	CDK9	TCEA1	TCEB3CL2	SFPQ	HNRNPK	ZCRB1	TSC2	FKBP1A	NCOR2	NCOR1	AKT1S1	TPST2	DDX5	TPST1	GGCX	GCKR	GCK	SEMA5A	CDK8	CYP2U1	CYP27A1	ABCD4	TBP	CYP19A1	CYP27B1	CHMP1A	CYP11B2	CYP11B1	CYP2R1	CYP21A2	TFDP1	TFDP2	FMO3	HDAC3	CEBPD	KHK	DAG1	CDKN1C	C1QBP	FGB	FGA	F10	VWF	GP1BB	F12	F11	FGG	GP1BA	F2	GP5	SLC4A1	GP9	SLC4A4	F8	F9	SERPING1	SLC34A3	SLC34A1	CBLL1	SH3KBP1	SLC9A6	SLC9A9	SLC26A2	SLC1A1	GAA	SLC5A5	GYG2	GYG1	CXCR4	SLC26A4	SLC26A3	TBL1X	SUZ12	SLC36A2	SLC7A7	STAT5A	STAT5B	PIK3CD	IRS2	SLC24A1	PIK3CB	SLC24A4	CDK5R1	VAV1	SLC20A2	GYS1	SLC3A2	PLCG2	JAK2	SLC17A8	SLC24A5	TBL1XR1	SMAD4	TALDO1	RPS6KB2	GCLC	GCLM	OPLAH	CYP1B1	CTNND1	ADAMTS2	ADAMTS3	ADAMTS14	XRCC4	CCR5	LIG4	CUL5	LUM	OGN	OMD	PRELP	KERA	FMOD	GNS	UGT1A4	ARAF	FRS2	EREG	BTC	TLN1	PIK3R4	PDGFB	TGFA	IQGAP1	BRAP	BRAF	PTK2	AREG	JAK3	JAK1	GAB2	RANGAP1	DUSP8	DUSP9	DUSP6	DUSP7	CNKSR2	APBB1IP	HCK	CNKSR1	MRAS	PTPN12	KIT	TLR9	HBEGF	SHOC2	EPGN	KLB	ACY1	ITGA2B	PEBP1	FGF1	FGF2	FGF3	FGF4	PPP1CC	FGF6	FGF7	FGF9	PDGFRB	PDGFRA	MAP2K1	CASP9	MAP2K2	HGF	VCL	CSF2RB	PHB	CSF2RA	RAP1B	RAP1A	FGF20	MARK3	FGF23	NEDD4L	FGF22	FGF16	FGF19	FGF18	NF1	FGFR4	GALNT3	MAP3K11	FGF10	ITGB3	PML	CCND2	ARRB1	ARRB2	DUSP16	SPRED3	SPRED2	SPRED1	DUSP10	PPP2R5E	KSR1	PPP2R5B	CYP4F22	PPP2R5A	PPP2R5D	NRG1	FDX1	PPP2R5C	FDXR	FDX1L	KSR2	NRG2	NRG3	NRG4	PIK3C3	MET	GSS	CAMK2B	CAMK2D	CSK	CAMK2G	PTPN11	EPS15	KRAS	SH3GL1	CDC25C	NPM1	OPN1SW	WDR48	OPN1MW	OPN1LW	OPN1MW2	RLBP1	EEF2	POMT2	SPON2	SEMA5B	SPON1	THSD7B	POMT1	C3	LFNG	ADAMTSL1	C1GALT1C1	IGHG4	ADAMTSL4	ADAMTSL3	IGHG1	ADAMTSL2	IGHG2	THSD7A	ADAMTS6	ADAMTS7	SBSPON	POMGNT1	ADAMTS20	B3GLCT	THBS2	CFP	ADAMTS12	THSD1	ADAMTS10	THSD4	ADAMTS15	ADAMTS13	ADAMTS19	LARGE	ADAMTS17	C1GALT1	B4GAT1	CYP24A1	BCL2L11	RNF213	SLC22A12	GTF2A1	GTF2A2	GTF2B	TAF9	TAF1L	AK6	GTF2E1	GTF2E2	TAF7L	TAF9B	TAF15	TAF12	TAF13	TAF10	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	ADORA2A	KDM1A	CTBP1	PHF21A	ABL1	PRDX2	PRDX1	SOD2	CDC25B	CDK5	RAB5A	SIN3A	HMG20B	RAC1	DOCK2	DOCK1	HDAC2	HDAC1	CDC42	SLC22A18	SLC6A20	SYK	CRK	RXFP1	RXFP2	GPR176	AP2A1	GNAT3	C3AR1	PTGDR	ENTPD1	ENTPD5	AP2A2	TXNIP	LHB	TXN	MEFV	CRHR2	MC2R	CGA	AP2M1	GPR15	CUBN	MC1R	NOX1	AMN	GPR27	GPR25	GPR20	MC4R	GPR39	DKK1	FSHB	DKK2	GPR32	DKK4	IL18	GPBAR1	MC3R	IL1A	IL1B	FSHR	NPSR1	PTGER4	KREMEN1	GPR45	KREMEN2	PTGER2	GNAI3	NOXO1	VAMP2	GNAI1	GNAI2	AP2S1	RNF43	NPS	NT5E	GPR150	GPHA2	P2RY11	MC5R	LRP5	ABCA1	LRP6	GPHB5	PYCARD	CYSLTR1	GGT1	LMBRD1	LHCGR	CYBA	DPEP2	AP2B1	DPEP1	DPEP3	MMACHC	GNAZ	MMADHC	GPR83	GPR84	CTBP2	DVL1	DVL2	NLRP3	DVL3	GGT5	NOXA1	RLN2	RLN3	PSTPIP1	CASP1	INSL3	TSHB	PTGIR	AVPR2	YWHAE	ADORA2B	TSHR	P2RX7	PPP1CB	POMC	P2RX4	SUGT1	PPP2R1A	PRKACA	GUCY2C	BTRC	SKP1	HSP90AA1	TUBB	SI	LCT	DYNLL1	AKAP9	UBA52	DYNC1I2	CUL1	UBB	PRKAR2B	UBC	RPS27A	DYNC1H1	MLH1	FGFR1OP	MAOA	CCNK	MAP1LC3B	DAXX	IL10	IL6	CD163	PLK2	RHBDF2	PMS2	CCNT2	SYT2	SYT1	MSH2	ST6GALNAC2	RPN2	PRKCSH	TUSC3	RPN1	MAGT1	GANAB	FUT8	MGAT5	ST3GAL4	PTEN	MGAT1	MGAT2	ST3GAL1	ST3GAL2	ST3GAL3	ST6GAL1	EDEM2	MOGS	DDOST	MGAT4C	DAD1	MGAT4A	MGAT4B	STT3A	MAN1B1	ST6GALNAC3	ST6GALNAC4	TXNRD1	HMGA1	PSIP1	FKBP4	SLC35D1	SLCO1B1	HDAC6	SLCO1B3	CD19	SLC35A2	SLC35A1	SLC35A3	SLC33A1	SLC35C1	SLCO2A1	PTGES3	AVP	SLC29A3	TRIM27	VAMP1	AGK	CAMK4	HIST2H2AB	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	HIST1H2AI	HIST1H2AH	HIST1H2AK	SDC4	HIST2H2BF	HIST3H2A	B3GAT3	SDC3	GPC3	SDC1	GPC2	GPC5	GPC4	GPC6	ETV6	KIAA1549	MPRIP	AGTRAP	AP3B1	SND1	PAPD7	ESRP1	KDM7A	FAM114A2	ZC3HAV1	TRAK1	PAPSS1	FXR1	ATG7	QKI	CLCN6	FAM131B	AGGF1	SLC5A7	PDZD3	PORCN	SLC2A1	AHCYL1	CD3G	PRKX	FCGR3A	FCGR1A	YES1	FGR	FCGR2A	RB1	NUP107	NUP188	GOLGA2	PPP2R1B	HIST1H2AE	HIST1H2AD	BANF1	HIST3H2BB	HIST1H2AC	HIST1H2AB	NUP214	NUP210	HIST1H2AJ	NUP93	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	NUP205	CCNH	POM121	CHD4	CHD3	HIST1H3J	AAAS	NUP160	MTA1	HIST1H3A	NUP85	RBBP4	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	RBBP7	HIST1H3I	MTA2	HIST1H3B	MTA3	HIST1H3C	MBD3	HIST1H3D	HIST1H3E	GTF2H1	NUP155	GTF2H2	GTF2H3	GTF2H4	HIST1H4K	GATAD2B	HIST1H4L	GTF2H5	GATAD2A	KAT2B	CDK7	NUP153	KAT2A	ERCC3	HIST1H4A	HIST1H4B	ERCC2	HIST1H4H	HIST1H4I	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	UGT1A1	HIST2H2AA3	HIST2H2AA4	LMNB1	HIST2H2AC	ZBP1	NUP62	TBK1	NDC1	SEC13	NUP133	HIST2H2BE	HIST4H4	NUP50	NUP54	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	CYP11A1	HIST1H2BL	HIST1H2BK	PPP2CA	HIST2H4A	PPP2CB	HIST2H4B	MAPK1	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	SLC25A5	SLC25A4	SLC25A6	B4GALT1	CD9	GLP1R	VIPR1	MSH6	VIPR2	SCT	IHH	ADM	PTH1R	SHH	CYSLTR2	GLP2R	PTH2R	GIP	ADCYAP1	CRH	IAPP	CALCA	RAMP2	ADCYAP1R1	RAMP3	CALCRL	CALCB	DHH	GIPR	PTH	PSMD8	IKBKB	PTH2	PSMD9	PSMD6	PTHLH	CRHR1	PSMD7	SLC2A9	PSMD4	GHRHR	PSMD5	PSMD2	CALCR	AMER1	PSMD3	AXIN1	PSMD1	IKBKG	APC	CHUK	PSMA5	PSMA6	WNT3A	PSMA3	PSMA4	FZD7	PSMA1	PSMA2	PSME3	SCTR	PSME4	PSME1	FZD8	PSME2	GCG	ADM2	PSMD10	PSMB11	GHRH	PSMD12	VIP	RAMP1	PSMD11	PSMD14	PSMD13	NOTCH1	PSMB10	PSMA7	RELA	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	E2F2	PSMB1	PSMF1	SHFM1	PSMB8	NFKB1	PSMB9	SLC6A19	NFKBIA	PSMC5	SLC6A18	PSMC6	PSMC3	PSMC4	PSMC1	SLC6A14	PSMC2	SLC6A2	SLC6A3	SLC6A5	SUMO1	UBE2I	IDH1	ESR1	SLC27A4	VHL	NOTCH3	NOTCH4	E2F3	IFNGR1	IFNGR2	PRR5	CD86	PDPK1	MAPKAP1	SLC7A9	CD80	SLC3A1	PIK3R3	PIK3R2	PIK3R1	MTOR	PIK3CA	ABCC8	LCK	AKT2	GPS2	AKT3	MLST8	CD28	AKT1	FYN	RICTOR	GSK3B	CCND1	SLC40A1	CDK4	HEPH	SLC11A2	NTHL1	GYS2	ATP6V1H	CP	RBP4	TTR	RDH12	RBP1	NAPEPLD	RDH5	LRAT	STRA6	TBXAS1	SLC12A3	SLC12A1	SLC12A6	SLC2A2	CAPNS1	CDK6	CDKN2A	CDH1	CAPNS2	BSG	CAPN2	CAPN1	CAST	ADAM10	HSPG2	BCAN	ADAM17	PSEN1	ADAMTS16	NCSTN	ADAMTS18	ADAMTS4	ADAMTS5	ADAMTS1	CTSL	ADRB1	SNAP25	ADRB2	SV2C	HTR4	SV2B	CTSG	SV2A	HTR6	ADAMTS8	HTR7	ADAMTS9	HRH2	DRD1	DRD5	TAAR8	TAAR9	DCN	TAAR6	TAAR5	TAAR2	TAAR1	ADRB3	FURIN	ARID4A	OGG1	ARID4B	COMT	NR3C1	ITGA4	IL1R1	NEIL3	SIGMAR1	KLKB1	ATP1B3	ATP1B2	TYK2	SLC1A3	ATP1B1	SAP30	BRMS1	IFNAR1	ATP1A4	ATP1A3	ATP1A2	ATP1A1	SAP30L	S1PR1	SAP18	SUDS3	BRD4	CRBN	STAT2	REST	FXYD4	FXYD3	IMPDH1	IMPDH2	FXYD2	FXYD1	FXYD7	FXYD6	PDCD1	RHOG	PAPSS2	CD8B	
INTERLEUKIN-1 PROCESSING%REACTOME DATABASE ID RELEASE 74%448706	Interleukin-1 processing	NFKB1	IL18	NFKB2	RELA	IL1A	IL1B	CASP1	CTSG	
APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS%REACTOME DATABASE ID RELEASE 74%111465	Apoptotic cleavage of cellular proteins	LMNB1	SPTAN1	ROCK1	CASP8	CASP6	PKP1	ADD1	PRKCQ	BIRC2	CTNNB1	CLSPN	PRKCD	CASP3	BMX	STK24	STK26	CDH1	OCLN	DBNL	DSP	GAS2	MAPT	TJP1	PLEC	SATB1	BCAP31	GSN	DSG1	FNTA	ACIN1	DSG2	VIM	DSG3	TJP2	PTK2	CASP7	APC	
OXYGEN-DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA-INDUCIBLE FACTOR ALPHA%REACTOME DATABASE ID RELEASE 74%1234176	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	UBE2D2	PSME3	CUL2	PSME4	UBE2D1	PSME1	EGLN1	PSME2	EGLN3	AJUBA	PSMD10	EGLN2	PSMB11	WTIP	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	TCEB2	TCEB1	PSMF1	EPAS1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	LIMD1	PSMC1	PSMC2	VHL	HIF3A	UBE2D3	RBX1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	HIF1A	PSMD1	PSMA5	
INACTIVATION, RECOVERY AND REGULATION OF THE PHOTOTRANSDUCTION CASCADE%REACTOME DATABASE ID RELEASE 74%2514859	Inactivation, recovery and regulation of the phototransduction cascade	GUCA1C	CNGA1	PDE6G	CAMKMT	RGS9BP	PRKCA	SAG	PPEF1	GUCY2D	GUCY2F	GRK1	GRK7	PRKCQ	GNAT1	RCVRN	GNB1	NMT1	NMT2	METAP1	METAP2	GNGT1	RHO	FNTA	CNGB1	FNTB	PDE6B	PDE6A	GUCA1B	GUCA1A	
NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION%REACTOME%R-HSA-112314.7	Neurotransmitter receptors and postsynaptic signal transmission	ADCY2	ADCY1	ADCY8	ADCY7	NEFL	CREB1	ADCY6	ADCY5	GNG12	GNG11	GNG13	GNB2	KIF17	NRGN	PRKCG	CASK	GNB1	GRIA1	GRIA2	GNB4	LIN7A	GNB3	LIN7C	GNB5	PPM1E	LIN7B	PPM1F	CAMKK1	CAMKK2	GRIN2A	PRKAR2B	GRIA3	LRRC7	GRIA4	GRIN2C	GRIN3B	AKAP5	GRIN3A	NBEA	CAMK4	APBA1	CAMK1	GRIN1	MAPK1	ARHGEF9	RAC1	KCNJ2	KCNJ3	KCNJ4	GABBR2	KCNJ5	KCNJ6	GABBR1	KCNJ10	KCNJ12	KCNJ9	KCNJ15	KCNJ16	PRKAA1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	DLG2	PRKAB2	PRKAB1	RASGRF2	RASGRF1	GABRG3	GABRG2	NRG1	EPB41L1	TSPAN7	GABRB3	GABRB2	GABRB1	GABRR3	GABRR2	GABRR1	RPS6KA3	PICK1	CAMK2B	RPS6KA6	CAMK2D	GLRA1	RPS6KA2	GLRA2	RPS6KA1	GLRA3	MAPK3	GABRA2	GABRQ	GABRA1	CAMK2G	GABRA6	GABRA5	GABRA4	GABRA3	GRIP1	MDM2	NRAS	GNAL	NPTN	HRAS	HTR3E	HTR3C	HTR3D	HTR3A	HTR3B	GNAT3	AP2A1	MYO6	GLRB	KPNA2	PRKX	GIT1	GNAI3	GNAI1	GNAI2	CACNG8	PRKCB	PRKCA	SRC	CACNG2	CACNG3	CACNG4	PDPK1	CHRNA1	CHRNB2	CHRNA3	CHRNB4	PRKACG	CHRNB3	PRKACB	CHRNA2	CHRNA5	GNGT1	CHRNA4	CHRNA7	CHRNA6	GNGT2	ADCY9	CHRNA9	PRKAR1B	CHRND	DLG1	CHRNG	PRKAR1A	DLG3	CHRNE	ACTN2	DLG4	PLCB3	GRIK5	PLCB1	GRIK3	PLCB2	PRKACA	PRKAR2A	GRIK4	CAMK2A	GRIK1	GRIK2	NCALD	GNG3	GNG10	GNG2	NSF	GNG5	GNG4	GRIN2B	GNG7	GNG8	GRIN2D	ADCY4	ADCY3	
FRS2-MEDIATED ACTIVATION%REACTOME DATABASE ID RELEASE 74%170968	Frs2-mediated activation	YWHAB	MAPK3	CRKL	RAPGEF1	MAPK1	NGF	BRAF	MAP2K1	RAP1A	MAP2K2	FRS2	
BIOSYNTHESIS OF E-SERIES 18(R)-RESOLVINS%REACTOME DATABASE ID RELEASE 74%9023661	Biosynthesis of E-series 18(R)-resolvins	LTA4H	ALOX15	ALOX5	
FGFR4 LIGAND BINDING AND ACTIVATION%REACTOME DATABASE ID RELEASE 74%190322	FGFR4 ligand binding and activation	FGF4	FGF16	FGF6	FGF9	FGF19	KLB	FGF18	FGFR4	FGF20	FGF1	FGF23	FGF2	
GLUCAGON-LIKE PEPTIDE-1 (GLP1) REGULATES INSULIN SECRETION%REACTOME%R-HSA-381676.2	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	ADCY8	ADCY6	ADCY5	KCNB1	GNG12	GNG11	GNG13	GCG	RAP1A	KCNS3	GLP1R	GNB2	KCNG2	GNB1	GNB4	GNB3	GNB5	PRKAR2B	RAPGEF3	AKAP5	PRKACG	PRKACB	RAPGEF4	GNGT1	GNGT2	PRKAR1B	PRKAR1A	PRKAR2A	PRKACA	ITPR1	ITPR2	ITPR3	KCNC2	GNAS	GNG3	IQGAP1	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	
PHOSPHORYLATION OF PROTEINS INVOLVED IN THE G2 M TRANSITION BY CYCLIN A:CDC2 COMPLEXES%REACTOME DATABASE ID RELEASE 74%170145	Phosphorylation of proteins involved in the G2 M transition by Cyclin A:Cdc2 complexes	CCNA2	CCNA1	CDK1	
PHASE 1 - INACTIVATION OF FAST NA+ CHANNELS%REACTOME DATABASE ID RELEASE 74%5576894	Phase 1 - inactivation of fast Na+ channels	KCNIP1	KCNIP2	KCNIP3	KCND1	KCNIP4	KCND2	KCND3	
DEFECTIVE SLCO2A1 CAUSES PRIMARY, AUTOSOMAL RECESSIVE HYPERTROPHIC OSTEOARTHROPATHY 2 (PHOAR2)%REACTOME DATABASE ID RELEASE 74%5619095	Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2)	SLCO2A1	
COLLAGEN FORMATION%REACTOME%R-HSA-1474290.2	Collagen formation	BMP1	COL9A1	COL9A3	COL9A2	COL18A1	COL14A1	LAMC2	CTSV	ITGA6	CTSS	MMP20	COLGALT2	PLOD3	PLOD2	PLOD1	CTSL	ADAMTS2	ADAMTS3	COLGALT1	P3H2	P3H1	PCOLCE	P3H3	PPIB	PCOLCE2	CTSB	ADAMTS14	MMP7	SERPINH1	CRTAP	COL25A1	P4HA1	P4HA2	MMP3	P4HA3	MMP9	MMP13	PLEC	LOXL3	COL15A1	LOXL4	LAMA3	COL19A1	COL11A1	LOXL1	COL11A2	COL26A1	LOXL2	COL10A1	LAMB3	COL28A1	COL27A1	COL24A1	COL22A1	COL1A1	COL3A1	COL1A2	COL2A1	LOX	TLL2	COL4A2	TLL1	COL5A1	COL4A1	COL6A2	COL4A4	COL7A1	COL5A3	COL4A3	COL5A2	COL6A1	P4HB	COL20A1	COL8A2	COL4A6	COL21A1	COL6A3	COL4A5	COL8A1	COL6A6	COL6A5	COL16A1	COL12A1	PXDN	COL23A1	CD151	COL17A1	ITGB4	COL13A1	
RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA%REACTOME DATABASE ID RELEASE 74%111457	Release of apoptotic factors from the mitochondria	DIABLO	BAX	BAK1	CYCS	
TRANSCRIPTIONAL REGULATION BY VENTX%REACTOME%R-HSA-8853884.2	Transcriptional Regulation by VENTX	CEBPB	EHMT1	UBE2D1	CDC23	CDC26	CDC27	TNRC6C	MOV10	ANAPC7	AGO3	UBE2E1	AGO4	AGO1	RELA	CTNNB1	ANAPC4	ANAPC5	TNRC6A	TNRC6B	EHMT2	ANAPC1	ANAPC2	CSF1R	ANAPC15	ANAPC16	VENTX	ANAPC10	ANAPC11	NFKB1	IL6	FZR1	CDKN2A	UBE2C	UBE2S	CDC16	LEF1	CCND1	TCF7L2	TP53	
THREONINE CATABOLISM%REACTOME%R-HSA-8849175.2	Threonine catabolism	SDSL	GCAT	SDS	HRSP12	
GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION%REACTOME DATABASE ID RELEASE 74%389661	Glyoxylate metabolism and glycine degradation	HOGA1	DDO	PDHA2	ALDH4A1	PDHA1	PRODH2	GOT2	LIPT2	GRHPR	LIPT1	LIAS	DHTKD1	HAO1	AMT	DAO	PDHB	PXMP2	NDUFAB1	DLST	AGXT2	DLAT	BCKDHA	OGDH	BCKDHB	DLD	GNMT	DBT	GLDC	GCSH	AGXT	PDHX	
TRANSLESION SYNTHESIS BY POLI%REACTOME DATABASE ID RELEASE 74%5656121	Translesion synthesis by POLI	RPS27A	POLI	REV1	RFC5	MAD2L2	RFC3	REV3L	PCNA	RPA1	RFC4	RPA2	RFC1	UBA52	RFC2	RPA3	UBB	UBC	
SYNTHESIS OF ACTIVE UBIQUITIN: ROLES OF E1 AND E2 ENZYMES%REACTOME%R-HSA-8866652.2	Synthesis of active ubiquitin: roles of E1 and E2 enzymes	UBE2Z	UBA6	UBE2D2	UBE2D1	CDC34	UBE2Q2	UBE2H	UBA52	UBE2E1	UBE2W	UBE2R2	UBE2L3	UBA1	UBE2K	UCHL3	UBE2E3	UBB	UBC	RPS27A	UBE2B	UBE2A	UBE2C	UBE2S	UBE2G1	USP5	UBE2G2	USP7	USP9X	OTULIN	UBE2T	
DISEASES OF THE NEURONAL SYSTEM%REACTOME DATABASE ID RELEASE 74%9675143	Diseases of the neuronal system	RBP1	NAPEPLD	RDH5	LRAT	STRA6	ABCA4	OPN1SW	RBP4	OPN1MW	TTR	OPN1LW	RDH12	OPN1MW2	RLBP1	
HEREDITARY FRUCTOSE INTOLERANCE%REACTOME%R-HSA-5657560.3	Hereditary fructose intolerance	ALDOB	
MET ACTIVATES RAP1 AND RAC1%REACTOME%R-HSA-8875555.1	MET activates RAP1 and RAC1	GAB1	CRKL	DOCK7	RAPGEF1	RAP1B	RAP1A	HGF	RAC1	CRK	MET	
CENTROSOME MATURATION%REACTOME%R-HSA-380287.1	Centrosome maturation	CSNK1E	TUBGCP4	TUBG2	DYNLL1	TUBG1	MZT2B	CKAP5	MZT2A	TUBA4A	NME7	HAUS2	MZT1	HAUS1	AKAP9	CEP63	CDK11A	MAPRE1	SFI1	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	HAUS8	HAUS7	PRKAR2B	CEP70	CEP72	CEP192	PCNT	CEP76	CLASP1	CEP78	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	CEP57	YWHAE	CETN2	CEP164	CCP110	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	NINL	CEP290	YWHAG	CDK5RAP2	OFD1	HSP90AA1	CEP135	TUBB	CEP131	TUBGCP2	HAUS4	HAUS3	CSNK1D	TUBGCP5	HAUS6	TUBGCP6	HAUS5	TUBGCP3	
MET ACTIVATES PTK2 SIGNALING%REACTOME%R-HSA-8874081.1	MET activates PTK2 signaling	LAMB3	LAMB2	LAMB1	LAMA2	LAMA1	SRC	ITGA3	LAMC2	ITGA2	LAMC1	ITGB1	LAMA5	LAMA3	PTK2	LAMC3	HGF	MET	LAMA4	
MAPK6 MAPK4 SIGNALING%REACTOME DATABASE ID RELEASE 74%5687128	MAPK6 MAPK4 signaling	PSMA6	PAK3	PSMA3	PSMA4	PAK2	PSMA1	PSMA2	PSME3	PSME4	FOXO1	PSME1	PSME2	PSMD10	TNRC6C	PSMB11	MOV10	UBA52	PSMD12	AGO3	PSMD11	AGO4	PSMD14	PSMD13	AGO1	PSMB10	AGO2	HSPB1	PSMA7	XPO1	PSMA8	PSMB6	TNRC6A	PSMB7	TNRC6B	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	RAG2	PSMB8	RAG1	RPS27A	PSMB9	KALRN	PSMC5	MYC	PSMC6	FOXO3	PSMC3	PSMC4	PSMC1	PSMC2	RAC1	CDK1	NCOA3	CDC42	CDC42EP5	CDC42EP3	CDC42EP2	CDC14B	SEPT7	ETV4	MAPK6	MAPK4	DNAJB1	IGF2BP1	CDC14A	CCND3	PRKACG	PRKACB	PRKACA	JUN	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	MAPKAPK5	PSMD5	PSMD2	PSMD3	PSMD1	PAK1	PSMA5	
REGULATION OF EXPRESSION OF SLITS AND ROBOS%REACTOME%R-HSA-9010553.1	Regulation of expression of SLITs and ROBOs	ROBO1	ISL1	SLIT1	UBA52	SLIT2	UBB	UBC	TCEB2	TCEB1	RPS27A	UPF2	HOXA2	ZSWIM8	MSI1	UPF3A	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	USP33	RPL7	COL4A5	RPS15	RPS14	EIF4A3	RPS17	CASC3	RPS16	RPL18A	RPS19	MAGOH	RPL36AL	NCBP1	RPS18	NCBP2	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	PSMD8	RPS6	RPSA	PSMD9	RPL24	ETF1	PSMD6	RPL27	PSMD7	RPL26	PSMD4	RPL29	RBM8A	PSMD5	RPL28	PSMD2	RPS4Y2	PSMD3	RPS4Y1	PSMD1	RPL39L	PSMA5	RPL41	PSMA6	PSMA3	UPF3B	RPL3L	PSMA4	MAGOHB	RPS26	PSMA1	RPS25	PSMA2	PSME3	CUL2	RPS28	RNPS1	PSME4	PSME1	RPS27	PSME2	RPS29	RPL27A	PSMD10	RPS20	RPS21	PSMB11	PSMD12	RPS24	PSMD11	RPS23	PSMD14	RPLP1	PSMD13	RPLP0	RPS4X	RPL7A	PSMB10	RPLP2	PSMA7	LHX3	RPL13A	PSMA8	LHX2	RPS3A	PSMB6	RPL37A	PSMB7	RPL10	PSMB4	LHX4	RPL12	PSMB5	LHX9	RPL11	PSMB2	RPL36A	PSMB3	PABPC1	RPS27L	PSMB1	PSMF1	RPS15A	SHFM1	RPL14	RPS3	PSMB8	GSPT2	RPL13	PSMB9	RPL15	GSPT1	RPS2	PSMC5	RPL18	PSMC6	RPL17	PSMC3	PSMC4	PSMC1	RPL19	PSMC2	RPL35A	RPL23A	EIF4G1	RPL22L1	FAU	RPL26L1	DAG1	RBX1	LDB1	ROBO2	
SUMOYLATION OF TRANSCRIPTION FACTORS%REACTOME DATABASE ID RELEASE 74%3232118	SUMOylation of transcription factors	CDKN2A	SP3	MDM2	TP53BP1	FOXL2	MITF	HIC1	PIAS1	SUMO1	UBE2I	SUMO3	SUMO2	PIAS4	PIAS3	TFAP2B	MTA1	TFAP2C	TP53	
SPERM MOTILITY AND TAXES%REACTOME DATABASE ID RELEASE 74%1300642	Sperm Motility And Taxes	CATSPER1	KCNU1	CATSPER3	CATSPERB	CATSPER2	CATSPERD	CATSPERG	CATSPER4	HVCN1	
FORMATION OF XYLULOSE-5-PHOSPHATE%REACTOME%R-HSA-5661270.2	Formation of xylulose-5-phosphate	AKR1A1	XYLB	CRYL1	DCXR	SORD	
NEF MEDIATED CD8 DOWN-REGULATION%REACTOME%R-HSA-182218.1	Nef Mediated CD8 Down-regulation	AP2A2	AP2M1	ATP6V1H	CD8B	AP2A1	AP2B1	AP2S1	
TRIGLYCERIDE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%75109	Triglyceride biosynthesis	DGAT2	DGAT1	GPAM	AGMO	LPIN1	LPIN2	LPIN3	GK2	GK	GPAT2	MOGAT3	MOGAT2	MOGAT1	
REGULATION OF TP53 EXPRESSION%REACTOME DATABASE ID RELEASE 74%6804754	Regulation of TP53 Expression	PRDM1	TP53	
NUCLEOTIDE-BINDING DOMAIN, LEUCINE RICH REPEAT CONTAINING RECEPTOR (NLR) SIGNALING PATHWAYS%REACTOME%R-HSA-168643.1	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	RIPK2	AAMP	MAPK12	ITCH	TRAF6	PANX1	UBE2V1	CYLD	TNFAIP3	BIRC2	RELA	BIRC3	NLRC4	UBE2N	TAB3	TAB2	NOD1	TAB1	NOD2	CASP2	MAPK13	IRAK2	NFKB1	TXNIP	TXN	MEFV	NLRP1	MAPK14	MAPK11	CASP4	AIM2	CASP9	CASP8	PYCARD	NLRP3	APP	PSTPIP1	CASP1	BCL2L1	P2RX7	BCL2	SUGT1	HSP90AB1	IRAK1	MAP2K6	IKBKB	NFKB2	IKBKG	CARD9	MAP3K7	CHUK	
FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC%REACTOME%R-HSA-389960.2	Formation of tubulin folding intermediates by CCT TriC	TUBAL3	TUBA3E	TUBA4A	TUBA1C	CCT7	TUBB6	CCT6A	TUBA1B	TUBA1A	TUBB3	TUBB1	TCP1	CCT6B	TUBB4B	TUBA8	TUBB4A	CCT8	CCT5	CCT4	TUBB2B	TUBB2A	TUBA4B	CCT3	CCT2	
TICAM1-DEPENDENT ACTIVATION OF IRF3 IRF7%REACTOME%R-HSA-9013973.2	TICAM1-dependent activation of IRF3 IRF7	RPS27A	TLR3	TICAM1	TBK1	UBB	IRF3	TRAF3	IRF7	UBC	TANK	UBA52	IKBKE	
VIRAL RNP COMPLEXES IN THE HOST CELL NUCLEUS%REACTOME%R-HSA-168330.3	Viral RNP Complexes in the Host Cell Nucleus	
DEFECTIVE SLC6A19 CAUSES HARTNUP DISORDER (HND)%REACTOME%R-HSA-5619044.1	Defective SLC6A19 causes Hartnup disorder (HND)	SLC6A19	
POST-TRANSLATIONAL PROTEIN PHOSPHORYLATION%REACTOME DATABASE ID RELEASE 74%8957275	Post-translational protein phosphorylation	TNC	PENK	TGOLN2	CP	TF	FBN1	IGFBP7	CST3	VCAN	APOA1	GPC3	MEN1	PNPLA2	MSLN	LTBP1	MIA3	BMP4	IGFBP1	ANO8	FGF23	CKAP4	FUCA2	MFI2	SPARCL1	IL6	HRC	FSTL1	GOLM1	DMP1	BMP15	ITIH2	LGALS1	MATN3	IGFBP3	ADAM10	MXRA8	CDH2	CHRDL1	ENAM	MFGE8	CSF1	PRKCSH	FSTL3	LAMB2	BPIFB2	PDIA6	RCN1	EVA1A	LAMC1	CHGB	MGAT4A	APLP2	WFS1	SERPINA10	PRSS23	PCSK9	TIMP1	AFP	SDC2	SCG3	KTN1	NUCB1	NOTUM	IGFBP5	SERPINA1	APOA2	IGFBP4	APOA5	DNAJC3	AMBN	CALU	TMEM132A	CYR61	MEPE	SPP1	APOE	APOB	LAMB1	QSOX1	AHSG	MBTPS1	APOL1	STC2	FAM20C	VWA1	FAM20A	ALB	SPP2	C3	P4HB	C4A	FN1	GAS6	APP	SERPINC1	KNG1	SHISA5	SCG2	AMELX	FGA	SERPIND1	HSP90B1	FGG	AMTN	F5	PROC	VGF	
REDUCTION OF CYTOSOLIC CA++ LEVELS%REACTOME DATABASE ID RELEASE 74%418359	Reduction of cytosolic Ca++ levels	ATP2A1	SLC8A3	ATP2B4	ATP2B3	SRI	SLC8A1	ATP2B2	SLC8A2	ATP2B1	ATP2A3	ATP2A2	
RETROGRADE TRANSPORT AT THE TRANS-GOLGI-NETWORK%REACTOME%R-HSA-6811440.1	Retrograde transport at the Trans-Golgi-Network	RAB9A	RAB9B	RHOBTB3	ARL1	TGOLN2	VTI1A	RAB6A	RAB6B	M6PR	IGF2R	RABEPK	NAA30	PLIN3	NAA35	NAA38	VAMP4	VAMP3	NAPA	NAPB	TMF1	STX16	USP6NL	SCOC	SYS1	NAPG	STX10	GCC2	GCC1	ARFRP1	RAB43	GOLGA4	VPS51	VPS53	VPS52	GOLGA1	ARFIP2	STX6	VPS54	NSF	COG8	COG7	RIC1	COG6	COG5	COG4	COG3	COG2	RGP1	COG1	
DNA METHYLATION%REACTOME%R-HSA-5334118.1	DNA methylation	HIST2H2AC	DNMT3A	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	DNMT1	HIST4H4	DNMT3B	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	HIST1H3A	UHRF1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	DNMT3L	H3F3B	HIST1H4K	HIST1H4L	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
ISG15 ANTIVIRAL MECHANISM%REACTOME%R-HSA-1169408.2	ISG15 antiviral mechanism	MAPK3	NUP62	JAK1	PIN1	IRF3	NDC1	SEC13	NUP133	UBA52	UBE2E1	NUP50	PLCG1	NUP54	UBE2N	UBB	UBC	KPNA7	KPNA4	KPNA5	KPNA2	RPS27A	KPNA3	UBE2L6	KPNA1	IFIT1	KPNB1	EIF4E	NUP43	EIF2AK2	HERC5	RAE1	ISG15	RANBP2	TRIM25	NUP35	NUPL2	EIF4G1	NUP37	NUP107	NUP188	NUP214	ARIH1	NUP210	FLNB	NUP93	UBA7	EIF4A2	EIF4A1	EIF4G3	EIF4G2	EIF4E3	DDX58	PPM1B	NUP205	POM121	EIF4A3	AAAS	USP41	NUP160	EIF4E2	NUP85	TPR	USP18	NUP88	NUP155	MX2	MX1	STAT1	NUP153	NEDD4	
RESPONSE TO METAL IONS%REACTOME%R-HSA-5660526.4	Response to metal ions	MT3	MT1E	CSRP1	MTF1	MT2A	MT1A	MT1M	MT1F	MT1G	MT1X	SNCB	MT1H	MT1B	MT4	
FGFR3B LIGAND BINDING AND ACTIVATION%REACTOME DATABASE ID RELEASE 74%190371	FGFR3b ligand binding and activation	FGF9	FGF18	FGF20	FGF1	
TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES%REACTOME DATABASE ID RELEASE 74%6796648	TP53 Regulates Transcription of DNA Repair Genes	FANCC	FOS	CHEK1	CTDP1	ELL	CCNT1	SUPT4H1	TCEB3	TCEB2	TCEB1	BRCA1	NELFA	NELFCD	TCEB3C	TCEB3CL	TCEB3B	NELFE	GTF2F1	SUPT16H	GTF2F2	SSRP1	SUPT5H	CDK9	TCEA1	TCEB3CL2	MLH1	MDC1	CCNK	ATR	NELFB	ATM	CDK12	CDK13	CCNH	ATF2	POLR2A	POLR2B	POLR2C	POLR2D	DDB2	RAD51D	POLR2E	POLR2F	PMS2	POLR2G	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	CCNT2	GTF2H3	GTF2H4	GTF2H5	JUN	CDK7	MSH2	ERCC3	FANCD2	ERCC2	MNAT1	FANCI	TP53	
SIGNALING BY NODAL%REACTOME%R-HSA-1181150.1	Signaling by NODAL	LEFTY2	DRAP1	FOXO3	LEFTY1	CER1	ACVR1B	ACVR1C	DAND5	SMAD4	SMAD2	FOXH1	SMAD3	ACVR2B	GDF1	CFC1	FURIN	ACVR2A	TDGF1	NODAL	PCSK6	
DEFECTIVE SLC12A1 CAUSES BARTTER SYNDROME 1 (BS1)%REACTOME%R-HSA-5619104.1	Defective SLC12A1 causes Bartter syndrome 1 (BS1)	SLC12A1	
INTERLEUKIN-6 SIGNALING%REACTOME%R-HSA-1059683.3	Interleukin-6 signaling	IL6	CBL	IL6R	PTPN11	IL6ST	JAK2	JAK1	TYK2	SOCS3	STAT1	STAT3	
PI5P, PP2A AND IER3 REGULATE PI3K AKT SIGNALING%REACTOME DATABASE ID RELEASE 74%6811558	PI5P, PP2A and IER3 Regulate PI3K AKT Signaling	MAPK3	AREG	IRAK4	PTPN11	TRAF6	PIP5K1C	EGF	GAB1	EGFR	KIT	HBEGF	INSR	PPP2CA	PPP2CB	EPGN	MAPK1	KLB	PIK3CD	RAC1	IRS2	FGF1	PIK3CB	FGF2	FGF3	FGF4	VAV1	FGF6	FGF7	FGF9	IL1RL1	PPP2R1B	PDGFRB	IL33	ESR1	PDGFRA	IER3	PIP5K1A	HGF	PIP5K1B	ESR2	STRN	IRS1	SRC	TRAT1	PIK3AP1	PIP4K2A	CD19	PIP4K2B	PIP4K2C	INS	FGF20	FGF23	FGF22	ERBB2	FGF16	CD86	CD80	PIK3R3	FGF19	PIK3R2	FGF18	RAC2	PIK3R1	FGFR4	PIK3CA	LCK	FGF10	CD28	AKT1	FYN	PPP2R1A	RHOG	PPP2R5E	FRS2	PPP2R5B	EREG	IRAK1	PPP2R5A	BTC	PPP2R5D	NRG1	PPP2R5C	PDGFB	TGFA	NRG2	MYD88	NRG3	NRG4	MET	
CYTOCHROME C-MEDIATED APOPTOTIC RESPONSE%REACTOME DATABASE ID RELEASE 74%111461	Cytochrome c-mediated apoptotic response	MAPK3	MAPK1	CYCS	AVEN	APAF1	DIABLO	CARD8	APIP	XIAP	UACA	CASP9	CASP3	CASP7	
AMYLOID FIBER FORMATION%REACTOME DATABASE ID RELEASE 74%977225	Amyloid fiber formation	HIST2H2AC	UBA52	H2AFZ	H2AFX	HIST2H2BE	HIST4H4	UBB	HIST1H2BN	HIST1H2BM	HIST1H2BO	UBC	HIST1H2BJ	HIST1H2BI	HIST1H2BL	RPS27A	HIST1H2BK	CST3	UBE2L6	HIST2H4A	SAA1	HIST2H4B	APOA1	GSN	LTF	USP9X	PARK2	TTR	LYZ	IAPP	CALCA	ADAM10	HSPG2	MFGE8	NCSTN	TSPAN14	APCS	ODAM	TSPAN33	SORL1	TSPAN15	B2M	NAT8	APOA4	SNCAIP	SNCA	TSPAN5	CALB1	BACE1	ITM2B	TGFBI	HIST1H2AE	SEMG1	HIST1H2AD	FURIN	HIST3H2BB	HIST1H2AC	HIST1H2AB	GGA2	GGA1	HIST1H2AJ	GGA3	HIST2H3A	INS	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	APP	HIST1H3J	NPPA	HIST1H3A	PRL	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	FGA	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	H3F3A	H2BFS	HIST1H4A	APH1A	HIST1H4B	HIST1H4H	APH1B	SIAH2	HIST1H4I	SIAH1	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	PSENEN	HIST2H2AA4	
ASPARAGINE N-LINKED GLYCOSYLATION%REACTOME DATABASE ID RELEASE 74%446203	Asparagine N-linked glycosylation	DYNC1LI1	DYNLL1	DYNC1LI2	SEC22A	SEC22C	B4GALT4	SEC23A	KDELR2	KDELR3	SEC13	COPB2	VCP	UBA52	COPA	TMED10	COPB1	SEC24B	SEC24A	DYNC1I2	SEL1L	DCTN2	DCTN3	GORASP1	MAN2A2	UBB	MAN2A1	RAB1A	SEC24D	SEC24C	UBC	RAB1B	USO1	RPS27A	MANEA	RNF185	LMAN1L	DYNC1H1	LMAN2L	COPE	ARF3	SCFD1	ARF4	ARF1	DERL1	DERL2	CAPZB	MAN1A2	RNF5	TMED3	OS9	TMED2	B4GALT1	MAN1A1	CTSZ	TMED7	TMED9	MIA2	MIA3	COPZ2	ARFGAP3	CTSC	DYNLL2	BET1L	DPM1	ARFGAP1	COPZ1	DPM2	DPM3	ARFGAP2	STX17	SEC23IP	SEC22B	ARF5	DCTN6	NAPA	TRAPPC2L	DCTN5	NAPB	TBC1D20	DCTN1	DCTN4	GOSR2	GOSR1	NAPG	MAN1C1	STX5	YKT6	DYNC1I1	GBF1	ARCN1	ST6GALNAC2	TRAPPC6A	RPN2	CAPZA3	PRKCSH	CAPZA1	TUSC3	RPN1	MAGT1	CAPZA2	TRAPPC6B	GANAB	FUT8	MGAT5	ST3GAL4	MGAT1	COPG2	MGAT2	PREB	ST3GAL1	COPG1	ST3GAL2	ACTR10	ST3GAL3	ST6GAL1	EDEM2	MOGS	DDOST	MGAT4C	DAD1	MGAT4A	MGAT4B	SEC31A	STT3A	MAN1B1	ST6GALNAC3	ST6GALNAC4	EDEM1	GFPT1	SYVN1	PSMC1	DPAGT1	ALG8	ALG9	ALG6	ALG14	ALG3	ALG13	ALG12	ALG1	MPDU1	RFT1	SLC35A1	SLC35C1	ST6GALNAC1	CMAS	MPI	GMPPB	NANP	FPGT	GMPPA	ALG2	PGM3	GNPNAT1	NANS	ALG11	NUDT14	ST6GAL2	ALG5	RENBP	CHST8	DHDDS	FUCA1	MVD	CHST10	ST6GALNAC5	FUT3	ST6GALNAC6	GNE	TSTA3	UAP1	NPL	FUOM	NEU2	NEU3	NEU4	GMDS	AMDHD2	NEU1	MGAT3	SLC17A5	TGFA	ST8SIA4	ST8SIA5	ST3GAL5	ST3GAL6	ST8SIA6	FUK	CTSA	NUS1	PMM1	ST8SIA1	ST8SIA2	GFPT2	SRD5A3	ST8SIA3	PMM2	DOLK	AREG	NAGK	GLB1	B4GALT6	DOLPP1	B4GALT5	GRIA1	COL7A1	B4GALNT2	TFG	ALG10B	ASGR1	UBXN1	ASGR2	NGLY1	RNF139	MLEC	UGGT2	UGGT1	LHB	PDIA3	EDEM3	AMFR	MARCH6	RAD23B	CGA	RNF103	TRIM13	CALR	ENGASE	SERPINA1	CANX	GOLGA2	SAR1B	LMAN1	SPTAN1	ANK2	ANK3	LMAN2	ANK1	SPTB	SPTBN4	UMOD	SPTBN5	TRAPPC10	INS	SPTA1	CD59	CD55	SPTBN1	SPTBN2	TMEM115	GOLGB1	FOLR1	BET1	ANKRD28	TRAPPC2	SEC16B	TRAPPC3	TRAPPC1	ALG10	TRAPPC4	SEC16A	ACTR1A	TRAPPC5	KDELR1	TRAPPC9	CNIH1	F5	NSF	CNIH2	COG8	F8	CNIH3	B4GALT2	COG7	B4GALT3	MCFD2	COG6	COG5	COG4	PPP6C	COG3	CSNK1D	COG2	PPP6R1	COG1	PPP6R3	
POST-CHAPERONIN TUBULIN FOLDING PATHWAY%REACTOME%R-HSA-389977.2	Post-chaperonin tubulin folding pathway	TUBAL3	ARL2	TUBA3E	TUBA4A	TUBA1C	TUBB6	TUBA1B	TUBA1A	TUBB3	TBCD	TUBB1	TBCC	TBCB	TBCA	TUBB4B	TUBA8	TUBB4A	TBCE	TUBB2B	TUBB2A	TUBA4B	
VITAMIN B5 (PANTOTHENATE) METABOLISM%REACTOME DATABASE ID RELEASE 74%199220	Vitamin B5 (pantothenate) metabolism	ENPP2	ENPP1	PPCDC	ENPP3	PDZD11	PPCS	COASY	SLC5A6	SLC25A16	VNN1	VNN2	PANK4	AASDHPPT	PANK2	PANK3	PANK1	FASN	
THE PHOTOTRANSDUCTION CASCADE%REACTOME%R-HSA-2514856.1	The phototransduction cascade	GUCA1C	CNGA1	PDE6G	CAMKMT	RGS9BP	PRKCA	SAG	PPEF1	GUCY2D	GUCY2F	GRK1	GRK7	PRKCQ	GNAT1	RCVRN	GNB1	NMT1	NMT2	METAP1	METAP2	GNGT1	RHO	SLC24A1	FNTA	CNGB1	FNTB	PDE6B	PDE6A	GUCA1B	GUCA1A	
DEFECTIVE AVP DOES NOT BIND AVPR2 AND CAUSES NEUROHYPOPHYSEAL DIABETES INSIPIDUS (NDI)%REACTOME%R-HSA-9036092.2	Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)	AVP	AVPR2	
MELANIN BIOSYNTHESIS%REACTOME%R-HSA-5662702.2	Melanin biosynthesis	TYRP1	DCT	OCA2	TYR	SLC45A2	
AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE%REACTOME%R-HSA-352230.3	Amino acid transport across the plasma membrane	SLC1A4	SLC1A5	SLC6A20	SLC38A3	SLC7A9	SLC3A1	SLC38A2	SLC38A5	SLC38A4	SLC16A10	SLC7A11	SLC7A10	SLC6A19	SLC36A1	SLC6A18	SLC36A2	SLC6A15	SLC7A5	SLC6A14	SLC7A6	SLC6A12	SLC7A7	SLC7A8	SLC6A6	SLC43A2	SLC43A1	SLC3A2	SLC7A1	SLC7A3	SLC25A29	SLC38A1	SLC36A4	
VLDL CLEARANCE%REACTOME%R-HSA-8964046.1	VLDL clearance	APOC1	APOB	APOC4	APOBR	LSR	VLDLR	
DAG AND IP3 SIGNALING%REACTOME DATABASE ID RELEASE 74%1489509	DAG and IP3 signaling	ADCY2	ADCY1	ADCY8	PRKCE	ADCY7	ADCY6	CAMK2G	CREB1	ADCY5	PRKCA	PRKCG	PDE1C	PDE1B	PDE1A	ADRBK1	PLCG1	CAMKK1	PRKCD	CAMKK2	PRKAR2B	PRKACG	PRKACB	KPNA2	NBEA	CAMK4	ADCY9	PRKAR1B	PRKAR1A	AHCYL1	PRKX	CAMK2A	PRKAR2A	PRKACA	ITPR1	ITPR2	ITPR3	CAMK2B	ADCY4	CAMK2D	ADCY3	
SYNTHESIS OF VERY LONG-CHAIN FATTY ACYL-COAS%REACTOME%R-HSA-75876.5	Synthesis of very long-chain fatty acyl-CoAs	HACD3	ACSL1	HACD2	TECRL	HACD4	HSD17B12	ACSL4	ACSL3	ACSL6	ELOVL4	ACSL5	ELOVL6	ELOVL7	ACSF3	ACSBG1	ACSBG2	ELOVL1	SLC27A3	ELOVL5	ELOVL2	ELOVL3	TECR	HSD17B3	HACD1	
MET PROMOTES CELL MOTILITY%REACTOME%R-HSA-8875878.1	MET promotes cell motility	LAMB3	LAMB2	LAMB1	LAMA2	LAMA1	SRC	TNS4	TNS3	RAP1B	RAP1A	ITGA3	LAMC2	LAMC1	GAB1	ITGB1	CRK	DOCK7	RAC1	ITGA2	CRKL	RAPGEF1	LAMA5	LAMA3	PTK2	LAMC3	HGF	MET	LAMA4	
EGFR DOWNREGULATION%REACTOME%R-HSA-182971.6	EGFR downregulation	SH3KBP1	AREG	STAM	HGS	EPS15	UBA52	SH3GL1	EGF	PTPN3	STAM2	CBL	EGFR	SH3GL2	UBB	SPRY2	PTPN12	UBC	HBEGF	RPS27A	EPGN	EREG	SH3GL3	BTC	TGFA	EPS15L1	CDC42	EPN1	PTPRK	SPRY1	ARHGEF7	
VOLTAGE GATED POTASSIUM CHANNELS%REACTOME DATABASE ID RELEASE 74%1296072	Voltage gated Potassium channels	KCNA3	KCNA4	KCNA5	KCNA6	KCNA7	KCNB1	KCNB2	KCNS1	KCNS2	KCNS3	KCNG1	KCNG2	KCNG3	KCNG4	KCNH1	KCNH2	KCNH3	KCNH4	KCNQ2	KCNH5	KCNQ3	KCNH6	KCNH7	KCNH8	KCNQ1	KCNQ4	KCNQ5	KCNV1	KCNV2	KCNF1	KCNC1	KCNC2	KCNC3	KCNC4	KCND1	KCND2	KCND3	KCNAB1	KCNAB2	KCNAB3	KCNA10	KCNA1	KCNA2	
DEFECTIVE SLC20A2 CAUSES IDIOPATHIC BASAL GANGLIA CALCIFICATION 1 (IBGC1)%REACTOME%R-HSA-5619111.1	Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1)	SLC20A2	
PINK1-PRKN MEDIATED MITOPHAGY%REACTOME%R-HSA-5205685.3	PINK1-PRKN Mediated Mitophagy	RPS27A	SQSTM1	MAP1LC3B	PINK1	MAP1LC3A	MTERF3	ATG12	UBA52	TOMM70A	TOMM7	TOMM5	TOMM6	UBB	PARK2	VDAC1	ATG5	TOMM20	MFN1	MFN2	TOMM22	UBC	TOMM40	
PI-3K CASCADE:FGFR3%REACTOME%R-HSA-5654710.2	PI-3K cascade:FGFR3	PTPN11	FRS2	FGF20	FGF1	FGF23	FGF2	GAB1	FGF4	FGF16	FGF9	FGF18	PIK3R1	PIK3CA	
CONJUGATION OF CARBOXYLIC ACIDS%REACTOME%R-HSA-159424.1	Conjugation of carboxylic acids	ACSM2B	GLYATL3	GLYATL2	GLYATL1	ACSM1	ACSM2A	ACSM5	ACSM4	GLYAT	
RAF ACTIVATION%REACTOME%R-HSA-5673000.2	RAF activation	RAF1	PHB	CAMK2G	SRC	MARK3	YWHAB	NRAS	HRAS	MRAS	MAP3K11	SHOC2	PPP2CA	PPP1CB	ARAF	PPP2CB	PPP2R1A	CAMK2A	PPP2R5E	KSR1	PPP2R5B	PPP2R5A	PPP2R5D	PPP1CC	PPP2R5C	JAK2	BRAP	PPP2R1B	BRAF	MAP2K1	MAP2K2	CAMK2B	CAMK2D	
DISEASES ASSOCIATED WITH THE TLR SIGNALING CASCADE%REACTOME DATABASE ID RELEASE 74%5602358	Diseases associated with the TLR signaling cascade	LY96	NFKB1	NFKBIA	IRAK4	TICAM1	TIRAP	TLR1	TRAF3	CD14	TLR4	TLR10	TLR6	TLR5	NFKB2	IKBKB	RELA	TLR3	MYD88	TLR2	UNC93B1	IKBKG	BTK	CD36	CHUK	
ACYL CHAIN REMODELLING OF PC%REACTOME%R-HSA-1482788.3	Acyl chain remodelling of PC	PLA2G4D	PLA2G4B	PLA2G4C	PLA2G4A	PLA2G16	PLA2G10	PLA2G1B	PLBD1	PLA2R1	PLA2G3	PLA2G2F	PLA2G5	PLA2G2D	PLA2G6	PLA2G2E	PNPLA8	PLA2G2A	MBOAT2	TMEM86B	LPCAT4	LPCAT3	LPCAT2	LPCAT1	PLB1	PLA2G12A	PLA2G4F	
BIOSYNTHESIS OF PROTECTIN AND RESOLVIN CONJUGATES IN TISSUE REGENERATION (PCTR AND RCTR)%REACTOME DATABASE ID RELEASE 74%9026766	Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR)	LTC4S	
ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE-3-KINASE (PI3K)%REACTOME%R-HSA-9027276.1	Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	GAB1	EPOR	PIK3R5	LYN	JAK2	PIK3R1	PIK3CA	EPO	PIK3CD	IRS2	PIK3CB	PIK3CG	
CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY%REACTOME%R-HSA-5357769.3	Caspase activation via extrinsic apoptotic signalling pathway	LY96	TNFRSF10B	UNC5A	TRAF2	MAGED1	UNC5B	TNFRSF10A	FASLG	TICAM1	CASP8	TNFSF10	FAS	RIPK1	CD14	FADD	TLR4	DAPK1	DAPK2	DAPK3	CASP3	DCC	APPL1	CASP9	TICAM2	TRADD	
DEPURINATION%REACTOME DATABASE ID RELEASE 74%73927	Depurination	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST3H3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	MPG	HIST1H2AJ	OGG1	TINF2	TERF1	TERF2	NEIL3	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
PROTEIN REPAIR%REACTOME%R-HSA-5676934.2	Protein repair	PCMT1	MSRB2	TXN	MSRB3	MSRB1	MSRA	
DEFECTIVE CYP21A2 CAUSES ADRENAL HYPERPLASIA 3 (AH3)%REACTOME DATABASE ID RELEASE 74%5579021	Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3)	CYP21A2	
RNA POLYMERASE I PROMOTER ESCAPE%REACTOME DATABASE ID RELEASE 74%73772	RNA Polymerase I Promoter Escape	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	TBP	HIST2H4A	HIST2H4B	POLR1C	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	HIST2H3A	HIST1H2BF	CBX3	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	RRN3	CCNH	H2AFB1	HIST1H3J	TAF1D	ZNRD1	HIST1H3A	TAF1B	TAF1C	POLR2E	HIST1H3F	TWISTNB	POLR2F	HIST1H3G	TAF1A	UBTF	HIST1H3H	POLR2H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	CD3EAP	POLR2K	HIST1H3E	POLR2L	GTF2H1	GTF2H2	H3F3B	GTF2H3	HIST1H4K	GTF2H4	HIST1H4L	GTF2H5	H3F3A	CDK7	H2BFS	ERCC3	POLR1A	HIST1H4A	POLR1B	HIST1H4B	ERCC2	HIST1H4H	POLR1E	HIST1H4I	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
PLATELET ACTIVATION, SIGNALING AND AGGREGATION%REACTOME DATABASE ID RELEASE 74%76002	Platelet activation, signaling and aggregation	TUBA4A	SPARC	MPL	THPO	MAPK1	STXBP3	ABCC4	APOA1	PIK3CB	PIK3CG	VAV1	PIK3R5	RAB27B	GNA13	PLCG2	LEFTY2	HSPA5	CD9	CD109	C6orf25	PDPN	CLEC1B	BRPF3	PRKCQ	RASGRP2	FAM49B	RASGRP1	ISLR	LAMP2	HABP4	LYN	FAM3C	CHID1	PRKCD	APLP2	ACTN1	YWHAZ	SERPINF2	ACTN4	GTPBP2	SYTL4	SEPP1	TMX3	TAGLN2	SCG3	NHLRC2	TEX264	STXBP2	ENDOD1	A1BG	CYB5R1	APOH	PSAP	VTI1B	TGFB2	TGFB3	MAPK14	RARRES2	IGF2	IGF1	PPBP	MANF	SELP	SCCPDH	CALU	MAGED2	CAP1	HRG	FERMT3	VAV3	LGALS3BP	SERPINA3	CLU	ORM1	VAV2	ECM1	WDR1	APOOL	PLEK	OLA1	SOD1	CTSW	ORM2	SERPINA4	GP6	TMSB4X	PHACTR2	TIMP3	QSOX1	SRC	SRGN	AHSG	ANXA5	P2RY12	MMRN1	FCER1G	TOR4A	CD63	ITIH4	ITIH3	TTN	GNA14	GNA15	CLEC3B	GNA11	CDC37L1	SPP2	GNA12	LY6G6F	TGFB1	GNAQ	PTPN6	F2RL2	PCDH7	LHFPL2	F2RL3	PDPK1	PCYOX1L	FN1	PIK3R3	PIK3R2	PIK3R1	RAC2	GAS6	PIK3CA	LCK	GNGT1	AKT1	GNGT2	FYN	ACTN2	ITPR1	TLN1	ITPR2	ITPR3	SERPINE1	PDGFB	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	PTK2	GNG8	RAF1	PLA2G4A	AAMP	GNG12	GNG11	GNG13	MGLL	GNB2	PRKCG	GNB1	GNB4	GNB3	GNB5	APBB1IP	TF	ITGA2B	RAC1	CDC42	PIK3R6	HGF	VCL	TBXA2R	ALDOA	FLNA	PPIA	RAP1B	RAP1A	RHOA	RHOB	PTPN1	SYK	CRK	RAPGEF3	BCAR1	RAPGEF4	ITGB3	LCP2	ARRB1	ARRB2	LAT	CFL1	DGKG	DGKE	DGKD	DAGLA	DGKB	DGKA	ABHD6	ABHD12	PRKCH	MAPK3	PRKCE	CSK	DGKZ	DGKQ	DAGLB	DGKK	PTPN11	A2M	DGKI	DGKH	PRKCZ	SHC1	EGF	SOS1	GNAT3	TIMP1	FIGF	TRPC7	VEGFB	TRPC6	VEGFC	TRPC3	VEGFA	SERPINA1	ADRA2C	ADRA2A	PLG	GNAI3	GNAI1	GNAI2	PRKCB	PRKCA	CFD	STX4	THBS1	ALB	APP	PROS1	F13A1	P2RY1	KNG1	PFN1	FGB	FGA	RHOG	VWF	GP1BB	F2R	FGG	GP1BA	F2	GP5	F5	GP9	F8	SERPING1	CD36	PF4	
DEFECTIVE CHST3 CAUSES SEDCJD%REACTOME DATABASE ID RELEASE 74%3595172	Defective CHST3 causes SEDCJD	BCAN	NCAN	CHST3	BGN	VCAN	DCN	CSPG5	CSPG4	
ACTIVATED POINT MUTANTS OF FGFR2%REACTOME DATABASE ID RELEASE 74%2033519	Activated point mutants of FGFR2	FGF20	FGF1	FGF23	FGF2	FGF22	FGF3	FGF4	FGF16	FGFR2	FGF6	FGF7	FGF9	FGF18	FGF10	
METHIONINE SALVAGE PATHWAY%REACTOME DATABASE ID RELEASE 74%1237112	Methionine salvage pathway	MRI1	ADI1	MTAP	GOT1	APIP	ENOPH1	
NEUROTRANSMITTER RELEASE CYCLE%REACTOME DATABASE ID RELEASE 74%112310	Neurotransmitter release cycle	RIMS1	BZRAP1	PPFIA1	PPFIA4	SLC1A1	PPFIA3	SLC1A2	PPFIA2	NAAA	CASK	SLC1A6	SLC1A7	CPLX1	LIN7A	LIN7C	GLS2	LIN7B	SLC38A2	STX1A	SNAP25	DNAJC5	GAD1	GAD2	APBA1	SLC22A2	SLC32A1	SLC22A1	SLC6A13	SLC6A12	SLC6A11	HSPA8	SLC6A1	SLC18A3	SLC18A2	MAOA	SLC17A7	VAMP2	GLS	RAB3A	SLC1A3	CHAT	ABAT	ARL6IP5	UNC13B	SYT1	SLC5A7	SYN3	SYN1	ALDH5A1	
INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION%REACTOME DATABASE ID RELEASE 74%168273	Influenza Viral RNA Transcription and Replication	NUP62	NDC1	SEC13	NUP133	UBA52	NUP50	NUP54	RPS27A	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	POLR2A	RPS16	POLR2B	RPL18A	POLR2C	RPS19	RPL36AL	POLR2D	RPS18	RPL36	POLR2E	RPL35	POLR2F	RPL38	RPL37	POLR2G	RPS11	POLR2H	RPL39	POLR2I	RPS10	POLR2J	RPS13	RPS12	POLR2K	RPS9	POLR2L	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	RPL3L	RPS26	RPS25	RPS28	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	IPO5	RPS27L	RPS15A	RPL14	RPS3	RPL13	RPL15	GTF2F1	RPS2	GTF2F2	RPL18	RPL17	RPL19	RPL35A	GRSF1	RPL23A	PARP1	DNAJC3	NUP107	RPL22L1	NUP188	FAU	RPL26L1	NUP214	NUP210	NUP93	NUP205	POM121	AAAS	NUP160	NUP85	TPR	NUP88	NUP155	NUP153	HSP90AA1	
ABC TRANSPORTER DISORDERS%REACTOME%R-HSA-5619084.5	ABC transporter disorders	PSMA6	PSMA3	PSMA4	PSMA1	ABCA12	PSMA2	ABCG8	PSME3	ABCG5	PSME4	PSME1	PSME2	CFTR	PSMD10	PSMB11	VCP	UBA52	PSMD12	PSMD11	ABCB6	PSMD14	PSMD13	ABCB4	SEL1L	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	ABCA3	PSMB4	UBB	PSMB5	PSMB2	ERLIN1	ABCD4	PSMB3	UBC	PSMB1	ERLIN2	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	RNF185	PSMC5	PSMC6	PSMC3	ABCD1	PSMC4	PSMC1	PSMC2	ABCC2	ABCC6	APOA1	ABCC9	DERL3	DERL1	DERL2	RNF5	ERLEC1	OS9	KCNJ11	ABCA1	ABCC8	ABCB11	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
DEFECTIVE SLC35A2 CAUSES CONGENITAL DISORDER OF GLYCOSYLATION 2M (CDG2M)%REACTOME DATABASE ID RELEASE 74%5619072	Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M)	SLC35A2	
AMER1 MUTANTS DESTABILIZE THE DESTRUCTION COMPLEX%REACTOME%R-HSA-4839748.1	AMER1 mutants destabilize the destruction complex	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	PPP2R1B	AMER1	AXIN1	APC	
ACROSOME REACTION AND SPERM:OOCYTE MEMBRANE BINDING%REACTOME%R-HSA-1300645.2	Acrosome Reaction and Sperm:Oocyte Membrane Binding	IZUMO4	IZUMO1	ACR	CD9	IZUMO3	IZUMO2	
RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES%REACTOME%R-HSA-8939242.1	RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	CTSV	SOCS4	CBFB	SERPINB13	CTSL	CTSK	SOCS3	RUNX1	
ESR-MEDIATED SIGNALING%REACTOME DATABASE ID RELEASE 74%8939211	ESR-mediated signaling	HIST2H2AC	FOS	H2AFJ	FOSB	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	SPHK1	NRIP1	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	ZDHHC7	HIST2H4B	MAPK1	GREB1	NR5A2	TFF1	KANK1	ZDHHC21	ZNF217	EBAG9	FOXA1	PPID	CAV2	CHD1	CXXC5	USF2	USF1	STRN	CITED1	YY1	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	CXCL12	POLR2H	POLR2I	POLR2J	HSP90AB1	POLR2K	POLR2L	GTF2A1	GTF2A2	AXIN1	SP1	KDM4B	XPO1	NCOA1	NCOA2	ESR1	NCOA3	FKBP4	SRC	PTGES3	PDPK1	S1PR3	PIK3R3	PIK3R2	PIK3R1	PIK3CA	NOS3	AKT2	AKT3	GNGT1	AKT1	GNGT2	CAV1	CCND1	EREG	BTC	TGFA	GNG3	GNG10	SMC3	KDM1A	GNG2	GNG5	MYB	GNG4	CREBBP	GNG7	PTK2	EP300	GNG8	PPP5C	RAD21	AREG	STAG1	STAG2	CREB1	GATA3	GNG12	GNG11	TLE3	GNG13	TNRC6C	MOV10	AGO3	AGO4	GNB2	SMC1A	AGO1	GNB1	AGO2	GNB4	GNB3	GNB5	TNRC6A	TNRC6B	CCNT1	CARM1	HBEGF	MYC	SRF	EPGN	FOXO3	UHMK1	GPAM	CDK9	MED1	HDAC1	PGR	FKBP5	BCL2	DDX5	MAPK3	CDKN1B	CBFB	PRKCZ	PRMT1	EGF	EGFR	NRAS	HRAS	GNAT3	KPNA2	POU2F1	CTSD	TBP	GTF2F1	GTF2F2	MMP7	MMP2	MMP3	MMP9	KCTD6	HIST1H2AE	HIST1H2AD	HIST3H2BB	GNAI3	HIST1H2AC	GNAI1	HIST1H2AB	GNAI2	ESR2	HIST1H2AJ	HIST2H3A	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	IGF1R	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H3J	ATF2	ELK1	HIST1H3A	RUNX1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	HIST1H4L	JUN	KAT2B	H3F3A	H2BFS	HSP90AA1	JUND	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
LOSS OF FUNCTION OF TGFBR2 IN CANCER%REACTOME DATABASE ID RELEASE 74%3642278	Loss of Function of TGFBR2 in Cancer	TGFB1	TGFBR1	TGFBR2	
PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR%REACTOME DATABASE ID RELEASE 74%392851	Prostacyclin signalling through prostacyclin receptor	GNGT1	GNGT2	GNG12	GNG11	GNG13	GNB2	GNB1	GNAS	GNG3	GNB4	GNG10	GNB3	GNG2	GNB5	GNG5	GNG4	GNG7	GNG8	PTGIR	
GSD II%REACTOME%R-HSA-5357609.3	GSD II	GYG1	GAA	
SYNTHESIS OF IP2, IP, AND INS IN THE CYTOSOL%REACTOME%R-HSA-1855183.5	Synthesis of IP2, IP, and Ins in the cytosol	MTMR9	ISYNA1	INPP1	MTMR7	INPP4A	INPP4B	INPP5A	IMPA1	INPP5J	INPP5B	IMPA2	MIOX	SYNJ1	OCRL	
DECTIN-2 FAMILY%REACTOME%R-HSA-5621480.3	Dectin-2 family	FCER1G	CLEC4A	CLEC4C	CLEC4D	CLEC4E	LYN	SYK	CLEC6A	MUCL1	MUC17	MUC5B	MUC3A	MUC5AC	MUC1	MUC7	MUC12	MUC13	FYN	MUC15	MUC20	CLEC10A	MUC4	MUC21	MUC6	PLCG2	
SCAVENGING BY CLASS B RECEPTORS%REACTOME%R-HSA-3000471.2	Scavenging by Class B Receptors	APOB	SSC5D	SAA1	APOA1	CD36	
CONVERSION FROM APC C:CDC20 TO APC C:CDH1 IN LATE ANAPHASE%REACTOME DATABASE ID RELEASE 74%176407	Conversion from APC C:Cdc20 to APC C:Cdh1 in late anaphase	FZR1	UBE2C	UBE2D1	CDC23	UBE2S	CDC26	CDC16	CDC27	ANAPC7	UBE2E1	CDC14A	ANAPC4	ANAPC5	CDC20	ANAPC1	ANAPC2	ANAPC15	ANAPC16	ANAPC10	ANAPC11	
MPS IIIC - SANFILIPPO SYNDROME C%REACTOME DATABASE ID RELEASE 74%2206291	MPS IIIC - Sanfilippo syndrome C	HGSNAT	
SEROTONIN AND MELATONIN BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%209931	Serotonin and melatonin biosynthesis	TPH1	AANAT	TPH2	DDC	ASMT	
STIMULI-SENSING CHANNELS%REACTOME%R-HSA-2672351.4	Stimuli-sensing channels	RAF1	BEST2	BEST3	SLC9C1	SLC9C2	BEST1	BEST4	UBA52	TRPC4AP	SLC9B1	SLC9B2	SCNN1G	SCNN1D	SCNN1B	SCNN1A	TTYH3	MCOLN1	TTYH2	CLCNKB	UBB	WNK4	CLCNKA	NALCN	TRPM1	UBC	TRPM2	ASIC4	ASIC5	CLCA2	RPS27A	CLCA1	TRPM7	TRPM8	ASIC2	TRPM5	TRPM6	ASIC3	CLCA4	TRPM3	ASIC1	TRPM4	TRPV2	WWP1	TRPV3	TRPV1	TRPV6	WNK1	WNK2	TRPV4	WNK3	TRPV5	RYR1	RYR2	RYR3	UNC80	CLIC2	TSC22D3	ANO8	ANO9	ANO6	ANO7	ANO4	ANO5	NEDD4L	ANO2	TRDN	ANO3	ANO1	ASPH	SGK3	SGK2	STOML3	SRI	CLCN6	CLCN3	CLCN2	CLCN1	BSND	ANO10	STOM	SGK1	SLC17A3	MCOLN3	TRPA1	MCOLN2	TPCN2	TPCN1	CLCN7	CLCN5	CLCN4	OSTM1	FKBP1B	UNC79	TRPC7	TRPC5	TRPC6	TRPC3	TRPC4	TRPC1	
DIGESTION OF DIETARY CARBOHYDRATE%REACTOME%R-HSA-189085.2	Digestion of dietary carbohydrate	AMY2B	TREH	AMY1B	AMY1C	CHIT1	SI	LCT	CHIA	MGAM	AMY2A	AMY1A	
TOLL LIKE RECEPTOR 3 (TLR3) CASCADE%REACTOME DATABASE ID RELEASE 74%168164	Toll Like Receptor 3 (TLR3) Cascade	RPS6KA1	RIPK3	RIPK2	MAPK3	FOS	CREB1	UBE2D2	UBE2D1	TBK1	DUSP4	IRF3	TRAF3	TRAF6	IRF7	UBA52	UBE2V1	DUSP6	BIRC2	DUSP7	TLR3	CUL1	RELA	BIRC3	UBE2N	UBB	TAB3	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	TANK	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	TICAM1	CASP8	RIPK1	FADD	ATF1	APP	ATF2	UBE2D3	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	AGER	BTRC	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	IKBKE	CHUK	RPS6KA2	DUSP3	
REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO%REACTOME%R-HSA-428542.3	Regulation of commissural axon pathfinding by SLIT and ROBO	NELL2	SRC	ROBO1	DCC	SLIT1	NTN1	SLIT3	ROBO2	SLIT2	
OXIDATIVE DEMETHYLATION OF DNA%REACTOME%R-HSA-5221030.2	Oxidative demethylation of DNA	TDG	TET2	TET1	TET3	
RNA POLYMERASE II TRANSCRIPTION TERMINATION%REACTOME%R-HSA-73856.4	RNA Polymerase II Transcription Termination	SRSF11	CHTOP	UPF3B	MAGOHB	RNPS1	CPSF7	CPSF1	CPSF3	CSTF3	CSTF2	CPSF2	CSTF2T	WDR33	NUDT21	FIP1L1	CLP1	PCF11	SNRPD3	PAPOLA	CSTF1	ZNF473	SYMPK	CPSF4	SLBP	PABPN1	LSM10	LSM11	EIF4A3	CASC3	SNRPG	MAGOH	NCBP1	NCBP2	SNRPE	THOC1	SNRPF	THOC3	THOC2	THOC5	THOC7	CDC40	SNRPB	SRRM1	THOC6	DDX39A	DDX39B	SARNP	ZC3H11A	SRSF2	SRSF3	SRSF4	SRSF5	SRSF6	SRSF7	SLU7	SRSF9	FYTTD1	LUZP4	RBM8A	POLDIP3	SRSF1	U2AF1	U2AF1L4	U2AF2	DHX38	
NICOTINATE METABOLISM%REACTOME%R-HSA-196807.3	Nicotinate metabolism	NT5E	NNMT	PTGS2	SLC5A8	NADK	PARP16	PARP14	PARP10	PARP6	PARP4	PARP9	PARP8	QPRT	NADK2	CARKD	RNLS	NMRK2	PTGIS	APOA1BP	SLC22A13	NAPRT	NMRK1	NAMPT	NUDT12	CD38	BST1	CYP8B1	NMNAT3	NMNAT2	NADSYN1	NMNAT1	
TRANSLESION SYNTHESIS BY POLH%REACTOME DATABASE ID RELEASE 74%110320	Translesion Synthesis by POLH	RPS27A	RFC5	RFC3	PCNA	RPA1	RFC4	RPA2	VCP	RFC1	UBA52	RFC2	RCHY1	RPA3	UFD1L	NPLOC4	SPRTN	POLH	UBB	UBC	
FGFR1C AND KLOTHO LIGAND BINDING AND ACTIVATION%REACTOME%R-HSA-190374.2	FGFR1c and Klotho ligand binding and activation	FGF23	
SIGNALING BY MEMBRANE-TETHERED FUSIONS OF PDGFRA OR PDGFRB%REACTOME%R-HSA-9673768.1	Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	KDR	ETV6	KANK1	GOLGA4	
SMAC(DIABLO)-MEDIATED DISSOCIATION OF IAP:CASPASE COMPLEXES%REACTOME%R-HSA-111464.3	SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	APAF1	DIABLO	XIAP	CASP9	CASP3	CASP7	CYCS	
RECEPTOR MEDIATED MITOPHAGY%REACTOME DATABASE ID RELEASE 74%8934903	Receptor Mediated Mitophagy	MAP1LC3B	CSNK2A1	ULK1	MAP1LC3A	FUNDC1	CSNK2A2	ATG5	ATG12	CSNK2B	
P53-INDEPENDENT G1 S DNA DAMAGE CHECKPOINT%REACTOME%R-HSA-69613.2	p53-Independent G1 S DNA damage checkpoint	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	CHEK2	PSME3	CHEK1	PSME4	PSME1	CDC25A	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
REGULATION OF ORNITHINE DECARBOXYLASE (ODC)%REACTOME%R-HSA-350562.2	Regulation of ornithine decarboxylase (ODC)	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	OAZ1	PSMA7	OAZ2	PSMA8	OAZ3	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	ODC1	NQO1	AZIN1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
SIGNALING BY ERBB4%REACTOME%R-HSA-1236394.4	Signaling by ERBB4	GABRQ	GABRA1	NCSTN	ITCH	UBA52	SHC1	EGF	EGFR	NRAS	SOS1	HRAS	UBB	TAB2	SPARC	UBC	HBEGF	RPS27A	S100B	STAT5A	STMN1	WWP1	ADAP1	GFAP	CSN2	ESR1	MXD4	WWOX	YAP1	APOE	SRC	PGR	PIK3R1	PIK3CA	NCOR1	CXCL12	DLG4	EREG	GABRG3	BTC	GABRG2	NRG1	PSEN2	GABRB3	NRG2	GABRB2	NEDD4	GABRB1	NRG3	ADAM17	APH1A	NRG4	APH1B	PSENEN	PSEN1	
DNA REPAIR%REACTOME%R-HSA-73894.3	DNA Repair	HIST2H2AC	POLK	XRCC1	H2AFJ	LIG3	VCP	UBA52	H2AFZ	H2AFX	H2AFV	CCNA2	CCNA1	HIST2H2BE	DTL	HIST4H4	MUS81	EME1	EME2	POLH	GEN1	SLX1B	UBB	HIST1H2BN	SPIDR	HIST1H2BM	SLX1A	RTEL1	HIST1H2BO	RAD51AP1	UBC	HIST1H2BJ	SLX4	HIST1H2BI	XRCC2	BRCA1	ACTL6A	HIST1H2BL	MAPK8	XRCC3	BRCA2	RPS27A	NBN	PALB2	TOP3A	HIST1H2BK	HIST2H4A	HMGN1	PPP4R2	ZNF830	HIST2H4B	TIPIN	BLM	UVSSA	TIMELESS	ERCC8	PPP4C	RBBP8	KDM4A	RPA1	RPA2	MRE11A	CDK2	HIST3H3	MLH1	RAD50	RAD51	RPA3	MDC1	YY1	MSH6	UBE2V2	XPA	PRKDC	PARP2	CHD1L	CUL4A	DDB1	POLR2A	POLR2B	ERCC5	POLR2C	CUL4B	POLR2D	DDB2	RAD51D	UBE2B	POLR2E	POLR2F	PMS2	POLR2G	POLR2H	POLR2I	POLR2J	RAD18	POLR2K	POLR2L	USP7	MSH2	FANCD2	FANCI	BABAM1	HERC2	FANCC	UIMC1	WHSC1	BAZ1B	RNF168	RNF8	BRCC3	APBB1	TP53BP1	KDM4B	EYA1	RCHY1	EYA2	EYA3	EYA4	BRE	FAM175A	STRA13	SUMO3	SUMO2	PIAS4	UBE2N	ALKBH3	PIAS3	XRCC6	FTO	ALKBH2	XRCC5	ALKBH5	PAXIP1	MGMT	ASCC1	ASCC2	ASCC3	USP10	POLI	REV1	USP43	MAD2L2	KIAA0101	REV3L	XRCC4	LIG4	PARG	PNKP	ADPRHL2	SUMO1	ACTB	UBE2I	SIRT6	PIAS1	RNF4	RBX1	NEIL2	NEIL1	TDG	MBD4	SMUG1	FAAP100	FAAP24	FAAP20	DCLRE1B	DCLRE1A	FANCM	POLQ	FANCL	FANCA	FANCB	FANCE	UFD1L	NPLOC4	FANCG	RNF111	SPRTN	FANCF	FAN1	POLN	EP300	PPP5C	NTHL1	TP53	MSH3	ABL1	SMARCA5	ELL	CLSPN	APITD1	UBE2L6	XPC	AQR	USP45	RAD23A	TCEA1	TRIM25	RAD51B	RAD51C	BRIP1	EXO1	PRPF19	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	RAD52	ERCC4	ERCC1	RAD17	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	UBA7	XAB2	ATM	PPIE	RFC5	RFC3	FEN1	PCNA	RFC4	RFC1	LIG1	RFC2	ISY1	POLE4	POLD3	POLB	POLD4	POLE2	POLD1	APEX1	POLE3	POLD2	POLE	UBE2T	DCLRE1C	RIF1	CHEK2	POLL	CHEK1	NHEJ1	RUVBL1	POLM	NFRKB	TDP2	TDP1	INO80C	INO80B	INO80E	INO80D	INO80	BAP1	COPS7B	ACTR5	COPS7A	ACTR8	TFPT	WDR48	MCRS1	KPNA2	RAD23B	ISG15	PARP1	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	GPS1	MPG	HIST1H2AJ	OGG1	TINF2	TERF1	TERF2	NEIL3	POT1	TERF2IP	ACD	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	CCNH	H2AFB1	CETN2	USP1	GTF2H1	GTF2H2	COPS4	GTF2H3	COPS3	HIST1H4K	GTF2H4	COPS6	HIST1H4L	GTF2H5	COPS5	CDK7	COPS2	H2BFS	ERCC3	HIST1H4A	HIST1H4B	COPS8	HIST1H4H	ERCC2	HIST1H4I	HIST1H4J	ERCC6	HIST1H4C	MNAT1	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE%REACTOME%R-HSA-1247673.1	Erythrocytes take up oxygen and release carbon dioxide	CA1	RHAG	SLC4A1	HBB	HBA2	AQP1	HBA1	CA2	CA4	
HIV ELONGATION ARREST AND RECOVERY%REACTOME DATABASE ID RELEASE 74%167287	HIV elongation arrest and recovery	CCNK	NELFB	CTDP1	ELL	CCNT1	SUPT4H1	POLR2A	TCEB3	POLR2B	TCEB2	POLR2C	TCEB1	NELFA	POLR2D	NELFCD	TCEB3C	POLR2E	TCEB3CL	POLR2F	TCEB3B	NELFE	GTF2F1	POLR2G	SUPT16H	GTF2F2	POLR2H	SSRP1	POLR2I	SUPT5H	POLR2J	CDK9	TCEA1	POLR2K	TCEB3CL2	POLR2L	CCNT2	
CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER%REACTOME DATABASE ID RELEASE 74%2219530	Constitutive Signaling by Aberrant PI3K in Cancer	AREG	PTPN11	EGF	GAB1	EGFR	KIT	HBEGF	EPGN	KLB	PIK3CD	RAC1	IRS2	FGF1	PIK3CB	FGF2	FGF3	FGF4	VAV1	FGF6	FGF7	FGF9	PDGFRB	ESR1	PDGFRA	HGF	ESR2	STRN	IRS1	SRC	TRAT1	PIK3AP1	CD19	FGF20	FGF23	FGF22	ERBB2	FGF16	CD86	CD80	PIK3R3	FGF19	PIK3R2	FGF18	RAC2	PIK3R1	FGFR4	PIK3CA	LCK	FGF10	CD28	FYN	RHOG	FRS2	EREG	BTC	NRG1	PDGFB	TGFA	NRG2	NRG3	NRG4	MET	
DEFECTIVE FMO3 CAUSES TRIMETHYLAMINURIA (TMAU)%REACTOME DATABASE ID RELEASE 74%5579019	Defective FMO3 causes Trimethylaminuria (TMAU)	FMO3	
DEFECTIVE PMM2 CAUSES PMM2-CDG (CDG-1A)%REACTOME%R-HSA-4043911.1	Defective PMM2 causes PMM2-CDG (CDG-1a)	PMM2	
BETA OXIDATION OF LAUROYL-COA TO DECANOYL-COA-COA%REACTOME%R-HSA-77310.2	Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	ACADL	HADHB	HADHA	ECHS1	HADH	
DEFECTIVE MOGS CAUSES MOGS-CDG (CDG-2B)%REACTOME%R-HSA-4793954.1	Defective MOGS causes MOGS-CDG (CDG-2b)	MOGS	
CLASSICAL ANTIBODY-MEDIATED COMPLEMENT ACTIVATION%REACTOME DATABASE ID RELEASE 74%173623	Classical antibody-mediated complement activation	IGKV2-28	CRP	IGKV1-12	C1QB	IGKV3D-20	C1QA	IGKV2D-28	IGKV4-1	C1S	C1R	IGKV2D-30	IGHG4	IGKV3-11	IGKV5-2	IGHG1	IGHG2	C1QC	
BIOSYNTHESIS OF PROTECTINS%REACTOME%R-HSA-9018681.1	Biosynthesis of protectins	LTA4H	CYP1A2	CYP1A1	ALOX15	
REGULATION OF KIT SIGNALING%REACTOME%R-HSA-1433559.1	Regulation of KIT signaling	CBL	PTPN6	LYN	PRKCA	FYN	SOS1	SOCS6	SOCS1	LCK	KIT	SH2B3	YES1	
CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION%REACTOME%R-HSA-69202.3	Cyclin E associated events during G1 S transition	PSMA6	PSMA3	CDKN1A	PSMA4	CDKN1B	PSMA1	PSMA2	PSME3	PSME1	CDC25A	PSME2	PSMD10	SKP2	UBA52	PSMD12	PSMD11	CCNA2	PSMD14	LIN54	CCNA1	PSMD13	RBL2	CCNE2	LIN37	CCNE1	MAX	PSMB10	LIN9	PSMA7	E2F4	CUL1	E2F5	LIN52	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	MYC	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CDK2	PTK6	RB1	TFDP1	TFDP2	CABLES1	WEE1	CKS1B	CCNH	AKT2	AKT3	RBBP4	AKT1	CCND1	CDK4	PSMD8	SKP1	CDK7	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	MNAT1	PSMD1	E2F1	PSMA5	
COBALAMIN (CBL, VITAMIN B12) TRANSPORT AND METABOLISM%REACTOME DATABASE ID RELEASE 74%196741	Cobalamin (Cbl, vitamin B12) transport and metabolism	MTRR	PRSS3	MMAB	GIF	MTR	CUBN	ABCC1	LMBRD1	AMN	MMACHC	MMADHC	CTRB2	CTRB1	ABCD4	MMAA	TCN2	TCN1	MUT	CD320	PRSS1	CTRC	
DEFECTIVE ABCG5 CAUSES SITOSTEROLEMIA%REACTOME%R-HSA-5679096.1	Defective ABCG5 causes sitosterolemia	ABCG8	ABCG5	
ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES%REACTOME DATABASE ID RELEASE 74%2022090	Assembly of collagen fibrils and other multimeric structures	BMP1	COL9A1	COL9A3	COL9A2	COL18A1	LAMC2	CTSV	ITGA6	CTSS	MMP20	CTSL	PCOLCE	CTSB	MMP7	MMP3	MMP9	MMP13	PLEC	LOXL3	COL15A1	LOXL4	LAMA3	COL11A1	LOXL1	COL11A2	LOXL2	COL10A1	LAMB3	COL27A1	COL24A1	COL1A1	COL3A1	COL1A2	COL2A1	LOX	TLL2	COL4A2	TLL1	COL5A1	COL4A1	COL6A2	COL4A4	COL7A1	COL5A3	COL4A3	COL5A2	COL6A1	COL8A2	COL6A3	COL4A5	COL8A1	COL6A6	COL6A5	PXDN	CD151	ITGB4	
DEFECTIVE SLC11A2 CAUSES HYPOCHROMIC MICROCYTIC ANEMIA, WITH IRON OVERLOAD 1 (AHMIO1)%REACTOME%R-HSA-5619048.1	Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1)	SLC11A2	
DIGESTION OF DIETARY LIPID%REACTOME%R-HSA-192456.4	Digestion of dietary lipid	LIPF	CLPS	PNLIPRP1	PNLIP	PNLIPRP3	
PLASMA LIPOPROTEIN ASSEMBLY%REACTOME%R-HSA-8963898.1	Plasma lipoprotein assembly	APOE	APOB	ABCA1	A2M	APOC4	APOA2	APOC3	PRKACA	APOA1	APOA4	APOC2	APOC1	P4HB	SAR1B	MTTP	ZDHHC8	PRKACG	PRKACB	
SMAC (DIABLO) BINDS TO IAPS%REACTOME DATABASE ID RELEASE 74%111463	SMAC (DIABLO) binds to IAPs	APAF1	DIABLO	XIAP	CASP9	CASP3	CASP7	CYCS	
ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY%REACTOME%R-HSA-442380.1	Zinc influx into cells by the SLC39 gene family	SLC39A6	SLC39A5	SLC39A8	SLC39A7	SLC39A2	SLC39A1	SLC39A3	SLC39A10	SLC39A4	SLC39A14	
TRNA PROCESSING%REACTOME%R-HSA-72306.6	tRNA processing	RPP40	NUP62	NDC1	SEC13	NUP133	NUP50	NUP54	RPP14	CPSF1	CSTF2	CLP1	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	TP53RK	TYW5	TYW3	TRMT5	TYW1	TRMT12	LCMT2	TRMT10C	ELAC2	KIAA0391	HSD17B10	POP5	POP7	POP1	CPSF4	POP4	TSEN54	ALKBH8	QTRTD1	GTPBP3	KIAA1456	TRMU	RAN	NUP107	NUP188	NSUN2	NSUN6	C14orf166	URM1	TRMT10A	ADAT1	TRMT1	ADAT2	TRMT6	TSEN2	THG1L	NUP214	NUP210	FTSJ1	THADA	WDR4	MTO1	QTRT1	EPRS	LAGE3	NUP93	TPRKB	TRIT1	TRMT61A	TRMT61B	RTCB	TRMT44	METTL1	OSGEP	C2orf49	TRMT13	NUP205	TRMT11	POM121	TRMT112	ZBTB8OS	DUS2	AAAS	CTU2	CTU1	NUP160	XPOT	PUS3	NUP85	CDKAL1	TPR	TRNT1	PUS7	NUP88	DDX1	TSEN15	TSEN34	TRDMT1	NUP155	FAM98B	NUP153	RPP30	RPP38	RPP21	RPP25	
PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%73817	Purine ribonucleoside monophosphate biosynthesis	IMPDH2	GART	GMPS	ADSS	LHPP	PAICS	PFAS	ATIC	PPAT	ADSL	IMPDH1	ADSSL1	
REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN%REACTOME DATABASE ID RELEASE 74%170822	Regulation of Glucokinase by Glucokinase Regulatory Protein	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	AAAS	NUP160	NUP85	TPR	NUP88	NUP43	RAE1	RANBP2	GCKR	NUP155	GCK	NUP35	NUPL2	NUP37	NUP107	NUP153	NUP188	
SIGNALING BY NOTCH1 IN CANCER%REACTOME%R-HSA-2644603.2	Signaling by NOTCH1 in Cancer	MIB2	MIB1	CCNC	NCSTN	NEURL1	MAML3	MAMLD1	HDAC4	UBA52	HDAC5	NOTCH1	HDAC8	HDAC9	HDAC7	CDK8	HEY1	HEY2	CUL1	UBB	UBC	HDAC10	HDAC11	RPS27A	TBL1X	MYC	SNW1	HDAC2	HDAC1	HDAC3	TBL1XR1	HDAC6	NCOR2	NCOR1	RBX1	MAML2	MAML1	KAT2B	SKP1	PSEN2	RBPJ	ADAM10	KAT2A	DLL1	HEYL	DLL4	ADAM17	APH1A	NEURL1B	APH1B	CREBBP	EP300	HES1	HES5	JAG2	PSENEN	PSEN1	JAG1	
MYD88 DEFICIENCY (TLR5)%REACTOME DATABASE ID RELEASE 74%5602680	MyD88 deficiency (TLR5)	TLR5	MYD88	
RIPK1-MEDIATED REGULATED NECROSIS%REACTOME%R-HSA-5213460.2	RIPK1-mediated regulated necrosis	RIPK3	TNFRSF10B	TRAF2	TNFRSF10A	FASLG	CASP8	TNFSF10	FAS	RIPK1	SDCBP	FADD	PELI1	UBA52	BIRC2	CDC37	PDCD6IP	BIRC3	STUB1	UBB	MLKL	UBC	OGT	RPS27A	FLOT1	FLOT2	HSP90AA1	XIAP	TRADD	
HEME DEGRADATION%REACTOME%R-HSA-189483.2	Heme degradation	ABCG2	SLCO1B1	SLCO1B3	ABCC1	ABCC2	UGT1A4	GSTA1	HMOX1	ALB	HMOX2	FABP1	BLVRB	BLVRA	
SIGNALING BY VEGF%REACTOME DATABASE ID RELEASE 74%194138	Signaling by VEGF	PAK3	PAK2	AAMP	JUP	CTNNB1	SPHK1	MAPK13	RAC1	PIK3CB	CTNNA1	SHB	VAV1	DOCK1	SH2D2A	AXL	CDC42	SHC2	ROCK1	ROCK2	RHOA	CRK	BCAR1	ITGB3	NCK2	ITGAV	RASA1	MAPK12	PRKCZ	CTNND1	HSPB1	NRAS	PLCG1	HRAS	PRKCD	MAPKAPK2	CDH5	FIGF	FLT1	FLT4	VEGFB	KDR	VEGFC	PGF	VEGFA	AHCYL1	CYFIP2	NCKAP1	CYFIP1	MAPK14	MAPK11	NRP1	NRP2	BRK1	NCK1	VAV3	VAV2	ELMO1	ELMO2	NCKAP1L	PRKCB	WASF1	WASF2	WASF3	PRKCA	PTK2B	BAIAP2	CYBA	ABI2	ABI1	PRR5	NCF1	PDPK1	NCF2	MAPKAP1	NCF4	PIK3R2	PIK3R1	MTOR	PIK3CA	NOS3	AKT2	PRKACG	AKT3	CYBB	PRKACB	MLST8	PXN	THEM4	AKT1	TRIB3	CAV1	FYN	RICTOR	MAPKAPK3	PRKACA	ITPR1	ITPR2	ITPR3	HSP90AA1	PTK2	PAK1	
ER TO GOLGI ANTEROGRADE TRANSPORT%REACTOME%R-HSA-199977.4	ER to Golgi Anterograde Transport	DYNC1LI1	DYNLL1	AREG	DYNC1LI2	SEC22A	SEC22C	SEC23A	KDELR2	KDELR3	SEC13	COPB2	COPA	TMED10	COPB1	SEC24B	SEC24A	DYNC1I2	GRIA1	DCTN2	DCTN3	GORASP1	RAB1A	SEC24D	SEC24C	RAB1B	USO1	LMAN1L	DYNC1H1	LMAN2L	COPE	ARF3	SCFD1	ARF4	ARF1	CAPZB	TMED3	TMED2	CTSZ	TMED7	TMED9	MIA2	MIA3	COPZ2	ARFGAP3	CTSC	DYNLL2	BET1L	ARFGAP1	COPZ1	ARFGAP2	STX17	COL7A1	SEC23IP	SEC22B	ARF5	DCTN6	TRAPPC2L	NAPA	DCTN5	NAPB	TBC1D20	DCTN1	DCTN4	GOSR2	GOSR1	NAPG	STX5	YKT6	DYNC1I1	GBF1	ARCN1	TRAPPC6A	CAPZA3	CAPZA1	CAPZA2	TRAPPC6B	TFG	COPG2	PREB	COPG1	ACTR10	SEC31A	SERPINA1	GOLGA2	SAR1B	LMAN1	SPTAN1	ANK2	ANK3	LMAN2	ANK1	SPTB	SPTBN4	SPTBN5	TRAPPC10	INS	SPTA1	CD59	CD55	SPTBN1	SPTBN2	TMEM115	GOLGB1	FOLR1	BET1	ANKRD28	TRAPPC2	SEC16B	TRAPPC3	TRAPPC1	TRAPPC4	SEC16A	TRAPPC5	ACTR1A	KDELR1	TRAPPC9	CNIH1	TGFA	F5	NSF	CNIH2	COG8	CNIH3	F8	COG7	MCFD2	COG6	COG5	COG4	PPP6C	COG3	CSNK1D	COG2	PPP6R1	COG1	PPP6R3	
DEFECTIVE MISMATCH REPAIR ASSOCIATED WITH PMS2%REACTOME%R-HSA-5632987.1	Defective Mismatch Repair Associated With PMS2	PMS2	MLH1	
BIOSYNTHESIS OF DPAN-3-DERIVED PROTECTINS AND RESOLVINS%REACTOME DATABASE ID RELEASE 74%9026286	Biosynthesis of DPAn-3-derived protectins and resolvins	ALOX15	ALOX5	
PROCESSING OF DNA DOUBLE-STRAND BREAK ENDS%REACTOME%R-HSA-5693607.1	Processing of DNA double-strand break ends	UBA52	H2AFX	CCNA2	CCNA1	HIST2H2BE	HIST4H4	UBB	CLSPN	HIST1H2BN	HIST1H2BM	HIST1H2BO	UBC	HIST1H2BJ	HIST1H2BI	BRCA1	HIST1H2BL	NBN	RPS27A	TOP3A	HIST1H2BK	HIST2H4A	PPP4R2	HIST2H4B	TIPIN	BLM	TIMELESS	PPP4C	RBBP8	RPA1	RPA2	CDK2	MRE11A	HIST3H3	RAD50	RPA3	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	MDC1	RAD17	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	ATM	UBE2V2	RFC5	RFC3	RFC4	RFC2	BABAM1	HERC2	UIMC1	WHSC1	CHEK1	RNF168	RNF8	BRCC3	TP53BP1	BRE	FAM175A	SUMO2	PIAS4	UBE2N	SUMO1	UBE2I	HIST3H2BB	SIRT6	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	RNF4	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	
MGMT-MEDIATED DNA DAMAGE REVERSAL%REACTOME DATABASE ID RELEASE 74%5657655	MGMT-mediated DNA damage reversal	MGMT	
TRYPTOPHAN CATABOLISM%REACTOME%R-HSA-71240.2	Tryptophan catabolism	SLC7A5	IDO2	IDO1	HAAO	AADAT	SLC3A2	KYNU	ACMSD	CCBL2	AFMID	CCBL1	KMO	TDO2	SLC36A4	
METABOLISM OF STEROID HORMONES%REACTOME%R-HSA-196071.2	Metabolism of steroid hormones	HSD17B1	HSD17B2	HSD11B1	HSD11B2	CYP17A1	BZRAP1	SERPINA6	STARD3	STARD4	STARD3NL	STARD6	STAR	CYP11A1	TSPO	SRD5A2	AKR1B1	SRD5A1	LHB	CYP19A1	POMC	HSD17B14	HSD17B12	HSD17B11	CGA	CYP11B2	CYP11B1	CYP21A2	FDX1	FDXR	FDX1L	AKR1B15	HSD17B3	HSD3B2	SRD5A3	HSD3B1	
VITAMIN B1 (THIAMIN) METABOLISM%REACTOME%R-HSA-196819.2	Vitamin B1 (thiamin) metabolism	SLC25A19	THTPA	TPK1	SLC19A3	SLC19A2	
MET ACTIVATES RAS SIGNALING%REACTOME DATABASE ID RELEASE 74%8851805	MET activates RAS signaling	RANBP9	NRAS	SOS1	HRAS	MUC20	HGF	MET	RANBP10	
DEFECTIVE F9 SECRETION%REACTOME%R-HSA-9673218.1	Defective F9 secretion	F9	
BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS%REACTOME DATABASE ID RELEASE 74%2173782	Binding and Uptake of Ligands by Scavenger Receptors	FTL	IGKV2-28	LRP1	IGKV1-12	IGKV3D-20	COLEC12	IGKV2D-28	IGKV4-1	IGKV2D-30	HPR	IGKV3-11	IGKV5-2	HPX	SPARC	IGHA1	HYOU1	SAA1	HBB	CALR	APOA1	MSR1	MARCO	STAB2	JCHAIN	APOE	APOB	STAB1	COL1A1	HBA2	COL3A1	HBA1	COL1A2	APOL1	COL4A2	COLEC11	HSPH1	COL4A1	HP	ALB	MASP1	SCARA5	CD163	AMBP	HSP90B1	FTH1	SSC5D	HSP90AA1	SCGB3A2	SCARF1	CD36	
CLATHRIN-MEDIATED ENDOCYTOSIS%REACTOME%R-HSA-8856828.3	Clathrin-mediated endocytosis	SH3KBP1	SGIP1	AREG	DNAJC6	FZD4	STAM	HGS	DNM1	NEDD8	DNM2	LRP2	CFTR	DNM3	FCHO1	FCHO2	UBA52	UBQLN1	UBQLN2	PIP5K1C	STAM2	HIP1R	TGOLN2	NECAP2	NECAP1	ADRBK1	SYT11	UBB	TF	RAB5A	UBC	HBEGF	M6PR	RPS27A	AGFG1	IGF2R	PIK3C2A	EPGN	SNX9	SNAP91	HIP1	ARFGAP1	GAK	CTTN	CLTB	TRIP10	SCARB2	VAMP4	CLTCL1	VAMP3	OCRL	AMPH	ARRB1	ARRB2	PACSIN2	PACSIN3	PACSIN1	SYT2	SYT1	SYT9	SYT8	IL7R	PICALM	SLC2A8	EPN1	EPN2	ITSN2	FNBP1L	REPS2	EPS15	REPS1	SH3GL1	FNBP1	GAPVD1	EGF	BIN1	CHRM2	AGTR1	CBL	COPS7B	EGFR	COPS7A	ADRB2	AP2A1	AP2A2	LDLRAP1	AP2M1	CD3G	HSPA8	CLTC	CLTA	STON1	STON2	ARPC1A	SLC18A3	WASL	CD3D	EPS15L1	ACTR3	TACR1	VAMP8	ACTR2	VAMP7	VAMP2	ARF6	GPS1	AP2S1	APOB	LDLR	ADRBK2	CD4	ARPC4	ARPC5	SNX18	ARPC2	AP2B1	ARPC3	DVL2	RAB5B	SH3GL2	RAB5C	AVP	KIAA0319	TOR1A	AVPR2	WNT5A	SYNJ2	TOR1B	TFRC	COPS4	COPS3	EREG	COPS6	SH3GL3	BTC	DAB2	COPS5	SYNJ1	TGFA	COPS2	AAK1	COPS8	ITSN1	
GRB7 EVENTS IN ERBB2 SIGNALING%REACTOME DATABASE ID RELEASE 74%1306955	GRB7 events in ERBB2 signaling	GRB7	NRG1	ERBB2	NRG2	
SYNTHESIS OF (16-20)-HYDROXYEICOSATETRAENOIC ACIDS (HETE)%REACTOME DATABASE ID RELEASE 74%2142816	Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	CYP2C9	CYP1B1	CYP2C19	CYP2C8	CYP4F2	CYP1A2	CYP1A1	CYP2U1	CYP4A11	
TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION%REACTOME%R-HSA-381340.2	Transcriptional regulation of white adipocyte differentiation	ADIRF	CCNC	TGS1	PPARGC1A	CDK8	NR2F2	RELA	MED19	MED16	MED15	MED18	MED17	CARM1	MED12	MED11	NFKB1	MED14	TBL1X	MED13	MED10	PCK1	MED27	MED26	EGR2	MED1	MED29	MED8	MED28	MED13L	MED9	MED23	MED4	MED22	MED25	MED24	MED21	MED6	MED20	PPARG	NCOA1	MED7	ANGPTL4	PPARA	NCOA2	NCOA6	NCOA3	CEBPA	SMARCD3	SREBF2	HDAC3	LPL	CEBPD	ZNF467	RXRA	FABP4	CEBPB	CDK19	TBL1XR1	ADIPOQ	KLF4	KLF5	LEP	CCND3	TGFB1	MED30	SLC2A4	MED31	EBF1	NCOR2	NCOR1	THRAP3	PLIN1	FAM120B	CDK4	TNF	HELZ2	ZNF638	CHD9	CREBBP	EP300	WNT1	CD36	WNT10B	
DEFECTIVE CYP27A1 CAUSES CEREBROTENDINOUS XANTHOMATOSIS (CTX)%REACTOME%R-HSA-5578996.3	Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX)	CYP27A1	
SYNTHESIS OF DOLICHYL-PHOSPHATE-GLUCOSE%REACTOME%R-HSA-480985.2	Synthesis of dolichyl-phosphate-glucose	ALG5	NUDT14	
CROSSLINKING OF COLLAGEN FIBRILS%REACTOME%R-HSA-2243919.2	Crosslinking of collagen fibrils	LOXL2	LOXL3	LOX	TLL2	LOXL4	BMP1	TLL1	PXDN	PCOLCE	LOXL1	
ORGANIC ANION TRANSPORTERS%REACTOME DATABASE ID RELEASE 74%428643	Organic anion transporters	SLC17A5	SLC5A5	SLC5A8	SLC25A18	SLC17A6	SLC17A7	SLC25A10	SLC17A8	SLC17A1	SLC25A22	
HEDGEHOG 'ON' STATE%REACTOME%R-HSA-5632684.1	Hedgehog 'on' state	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	CSNK1A1	PSME1	PSME2	ITCH	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	ADRBK1	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	EVC2	IQCE	SHFM1	EFCAB7	PSMB8	EVC	RPS27A	GAS8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CUL3	CDC73	SMURF2	SMURF1	IHH	CDON	SHH	RBX1	ARRB1	ARRB2	SMO	GPR161	KIF3A	PTCH1	DHH	PSMD8	DZIP1	GLI1	SPOP	GLI3	PSMD9	GLI2	PSMD6	PSMD7	PSMD4	SUFU	PSMD5	PSMD2	PSMD3	KIF7	ULK3	PSMD1	SPOPL	HHIP	NUMB	BOC	GAS1	PSMA5	
LATE ENDOSOMAL MICROAUTOPHAGY%REACTOME DATABASE ID RELEASE 74%9615710	Late endosomal microautophagy	VPS37C	VPS37D	VPS37A	VPS37B	HDAC6	CHMP2B	CHMP2A	CHMP4C	CFTR	CHMP4B	UBAP1	CHMP3	UBA52	CHMP4A	CHMP6	CHMP7	PLIN3	VPS28	UBB	UBC	RPS27A	PCNT	ARL13B	IFT88	HBB	HSPA8	PLIN2	CETN1	PARK7	TSG101	MVB12B	MVB12A	RNASE1	
CHYLOMICRON CLEARANCE%REACTOME%R-HSA-8964026.1	Chylomicron clearance	APOE	APOB	LIPC	LDLR	LDLRAP1	
CYCLIN D ASSOCIATED EVENTS IN G1%REACTOME%R-HSA-69231.7	Cyclin D associated events in G1	CDKN1A	CDKN1B	E2F3	CKS1B	PPP2R2A	ABL1	SKP2	PPP2R3B	UBA52	CCND3	RBL2	CCNE2	RBL1	CCNE1	E2F4	CUL1	E2F5	CDKN1C	LYN	CCNH	UBB	UBC	E2F2	CDKN2D	CDKN2B	CDKN2C	RPS27A	PPP2CA	CCND2	PPP2CB	CDK6	CDKN2A	PPP2R1A	CDK2	CCND1	CDK4	PTK6	RB1	SKP1	CDK7	TFDP1	JAK2	TFDP2	PPP2R1B	MNAT1	E2F1	
RAS ACTIVATION UPON CA2+ INFLUX THROUGH NMDA RECEPTOR%REACTOME%R-HSA-442982.3	Ras activation upon Ca2+ influx through NMDA receptor	RASGRF2	RASGRF1	GRIN1	NEFL	CAMK2G	DLG1	DLG3	ACTN2	DLG4	CAMK2A	NRAS	DLG2	HRAS	GRIN2B	GRIN2D	LRRC7	CAMK2B	CAMK2D	
DISEASES OF CELLULAR RESPONSE TO STRESS%REACTOME%R-HSA-9675132.2	Diseases of cellular response to stress	CDK6	CDKN2A	CDK4	
DEFECTIVE HK1 CAUSES HEXOKINASE DEFICIENCY (HK DEFICIENCY)%REACTOME%R-HSA-5619056.2	Defective HK1 causes hexokinase deficiency (HK deficiency)	HK1	
SEMA3A-PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION%REACTOME DATABASE ID RELEASE 74%399955	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	RRAS	FYN	PLXNA2	FARP2	PLXNA1	RAC1	PIP5K1C	PLXNA4	RND1	TLN1	PLXNA3	NRP1	FES	SEMA3A	
NADE MODULATES DEATH SIGNALLING%REACTOME DATABASE ID RELEASE 74%205025	NADE modulates death signalling	NGF	NGFR	CASP3	CASP2	NGFRAP1	YWHAE	
BIOSYNTHESIS OF DPAN-3-DERIVED MARESINS%REACTOME DATABASE ID RELEASE 74%9026290	Biosynthesis of DPAn-3-derived maresins	ALOX12	ALOX5	
PTK6 ACTIVATES STAT3%REACTOME%R-HSA-8849474.1	PTK6 Activates STAT3	STAP2	SOCS3	STAT3	PTK6	
HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE%REACTOME%R-HSA-5693579.1	Homologous DNA Pairing and Strand Exchange	RAD17	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	CHEK1	KAT5	ATM	RAD51AP1	BRCA1	XRCC2	BRCA2	XRCC3	NBN	PALB2	TOP3A	RAD51D	BLM	RFC5	RFC3	RBBP8	RPA1	RFC4	RPA2	MRE11A	RFC2	RAD51B	RAD50	RAD51C	RAD51	RPA3	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	WRN	RMI1	HUS1	
DEFECTIVE MISMATCH REPAIR ASSOCIATED WITH MLH1%REACTOME%R-HSA-5545483.1	Defective Mismatch Repair Associated With MLH1	PMS2	MLH1	
2-LTR CIRCLE FORMATION%REACTOME DATABASE ID RELEASE 74%164843	2-LTR circle formation	XRCC6	XRCC5	XRCC4	BANF1	HMGA1	PSIP1	LIG4	
METABOLISM%REACTOME DATABASE ID RELEASE 74%1430728	Metabolism	ABCB1	ABCB7	ABCB4	RTEL1	ABCD1	ABCC3	ABCC1	ABCC2	ABCC5	APOA1	KCNJ11	PIP5K1A	PIP5K1B	BST1	VNN1	VNN2	FOLR2	MAPKAPK2	PSAP	WASL	PAH	PRKACG	PRKACB	ADCY9	PRKAR1B	PRKAR1A	UGT2B10	UGT1A10	UGT2B11	PRKAR2A	UGT2B15	UGT2B17	UGT2B28	UGDH	ABHD10	GNAS	UGP2	UGT1A5	UGT2A3	UGT3A2	UGT2B4	UGT3A1	UGT1A3	UGT1A8	UGT2B7	UGT1A7	UGT1A6	ADCY4	ADCY3	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY5	MMAB	GLO1	LDHC	LDHB	LDHA	PDPR	MPC1	MPC2	PDK4	PDK3	PDK2	PDK1	PDP1	PDP2	LDHAL6A	LDHAL6B	FH	FAHD1	MDH2	IDH3G	IDH2	DLST	SDHC	SDHD	SDHA	SDHB	CS	PRPS2	SUCLA2	EBP	PRPS1	SC5D	NNT	IDH3B	RPEL1	DHCR24	OGDH	DHCR7	RPE	PGD	SUCLG2	SUCLG1	DERA	ME3	RPIA	SHPK	GPI	ME2	ACO2	PGLS	ADPGK	RBKS	DLD	ENO1	IDH3A	ELOVL1	ENO2	FADS2	ENO3	SCP2	HK2	HK1	ELOVL5	HK3	ELOVL2	TPI1	ELOVL3	PGAM1	PGAM2	PIK3R6	BPGM	HSD3B7	GAPDHS	PGP	AKR1D1	AKR1C2	ALDOC	ALDOB	ALDOA	GAPDH	PFKFB2	PFKFB1	PFKFB4	PFKFB3	PGK1	PGK2	PFKL	GNPDA1	GNPDA2	PFKM	PFKP	GDA	DPYS	BTD	NUDT5	PPP1R3C	NT5C2	NHLRC1	HLCS	DNPH1	TCN2	TYMP	CD320	NT5C	UPP2	GBE1	NT5M	UPP1	NUDT16	NUDT15	XDH	EPM2A	ENTPD2	ACACA	G6PC3	ENTPD3	AGXT2	GIF	ENTPD4	ENTPD6	DCXR	PCCA	ENTPD7	PCCB	ENTPD8	UPB1	NT5C1A	DPYD	PC	NT5C1B	ADPRM	ITPA	POLD1	PANK4	VKORC1L1	ALDH1L1	PANK2	PANK3	PANK1	NADSYN1	ALDH1L2	FLAD1	ENPP2	ENPP1	ENPP3	PRSS3	MTHFD1	MTHFD2	MTHFD2L	UBIAD1	SHMT2	ACACB	PPCS	PNPO	SLC19A3	NADK	SLC19A1	SLC19A2	SLC52A2	SLC52A3	SLC52A1	MTHFR	MTHFS	COQ9	COQ7	COQ6	COQ5	DHFR	COQ3	CHPF	TCN1	HPSE2	FASN	XYLT2	XYLT1	CTRC	MOCS2	HS6ST1	MOCS3	HS6ST2	HS6ST3	QPRT	NDST2	GPHN	NDST1	PPCDC	THTPA	NAGLU	NDST4	NADK2	NDST3	SPR	CHP1	DHFRL1	NMRK2	CSGALNACT1	GLCE	RFK	NMRK1	CSGALNACT2	ACP5	CEMIP	HS3ST3A1	AOX1	HMMR	CD38	VKORC1	CHST11	CHST12	COASY	GCHFR	DSEL	SLC25A16	CHST15	SLC25A19	CHST13	PDXK	CHST14	PTS	B3GALT6	EXT1	MTHFD1L	LGMN	EXT2	PDSS2	PDSS1	UST	HPSE	AASDHPPT	GCH1	B4GALT2	TPK1	B4GALT3	MOCOS	SGSH	HS2ST1	NMNAT3	PPARGC1B	HYAL2	NMNAT2	DSE	CD36	NMNAT1	SLC25A32	GUSB	HS3ST3B1	CHST7	CHPF2	CHST1	B4GALT7	CHST5	B4GALT4	CHST2	CHST3	DNM2	CHSY1	HAS1	FABP9	HAS3	ABHD5	HAS2	FABP12	CHSY3	LIPE	FABP2	B3GAT2	FABP3	B3GAT1	HS3ST5	FABP5	HS3ST6	FABP6	PNPLA4	LYVE1	PNPLA5	HS3ST4	HS3ST1	HS3ST2	PPARD	ARF3	ARF1	ZDHHC21	SCD	RORA	PLIN3	ABCB11	SLC16A1	GALT	GALE	PGM1	GALK1	ACADVL	SP1	SULT1A3	SLC16A8	SLC16A3	RXRB	G6PC	GNGT1	GNGT2	MVD	VDR	CAV1	PRKG2	ST6GALNAC6	PLCB3	PLCB1	PLCB2	NEU2	NEU3	RRM2	ITPR1	ITPR2	NEU1	ITPR3	GNG3	GNG10	GNG2	ST3GAL6	ADH1C	ADH1A	GNG5	GNG4	CTSA	GNG7	CYP26A1	GNG8	ADH4	CYP26B1	CYP26C1	SRD5A3	ALDH1A1	GLB1	GNG12	CYP17A1	GNG11	GNG13	NR1D1	GNB2	GNB1	DUOX1	GNB4	TPO	GNB3	IYD	DIO1	GMPR2	GNB5	DIO2	ADK	GMPR	DIO3	DUOX2	AMPD1	AMPD2	AMPD3	DCK	APRT	ADAL	DGUOK	PNP	HPRT1	ADA	IDUA	HEXB	NCAN	HEXA	BGN	VCAN	HYAL1	HYAL3	IDS	CSPG5	CSPG4	ARSB	PTGS2	MLXIPL	SLC23A2	CYB5A	CYB5R3	GSTO2	SLC23A1	ESRRA	SRR	PSAT1	SERINC1	PHGDH	SERINC3	SERINC2	PSPH	SERINC5	SERINC4	LBR	FUT2	FUT1	TTPA	PECR	PHYH	SLC25A17	HACL1	SLC27A2	PLCG1	DARS	SLC2A3	SARS	EPRS	AIMP1	AIMP2	QARS	KARS	PPA1	LARS	MARS	KCNG2	RARS	IARS	EEF1E1	KCNC2	TPH1	KCNB1	KCNS3	VDAC1	CYP7B1	RPL4	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	ACLY	FABP7	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	TKFC	RPL39L	OSBPL1A	RPL41	N6AMT1	MTRR	RPL3L	NNMT	RPS26	AHCY	RPS25	TPMT	RPS28	GSTO1	RPS27	MTR	RPS29	MAT2B	RPL27A	MAT1A	RPS20	AS3MT	RPS21	MAT2A	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	RPS27L	RPS15A	RPL14	RPS3	RPL13	RPL15	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	RPL22L1	FAU	RPL26L1	NUDT19	GSTK1	PIPOX	ACOT2	HAO1	HAO2	ACBD5	NOS3	COQ2	DAO	AMACR	PXMP2	HSCB	GLA	CROT	CDA	BAAT	ACOX2	AGPS	ACOX3	SLC25A12	AGXT	EP300	FXN	PAOX	SLC25A13	DDO	NUDT7	VAPA	CRAT	BMX	RBP2	RETSAT	LRP8	APOM	BCO2	BCO1	AKR1C1	AKR1C4	AKR1B10	LRP10	LRP12	CYP4F12	FADS1	SULT2A1	CPT1A	ACSL1	CLOCK	PEX11A	NRF1	NPAS2	FDFT1	ALAS1	FHL2	GLIPR1	CPT2	ME1	BCKDHA	ACAD8	ANKRD1	ACADM	MCCC2	HIBADH	HMGCS1	CYP4A11	BCKDHB	MTF1	MCCC1	PLIN2	PPM1K	TNFRSF21	ACADSB	BCKDK	CYP7A1	ALDH6A1	ARNTL	UGT1A9	AUH	NR1H4	IVD	G0S2	DBT	BCAT1	GRHL1	SLC25A44	AGT	FABP1	HIBCH	BCAT2	ALOX15	ALOX12	SLC22A5	MID1IP1	THRSP	SLC25A20	CPT1B	KPNB1	RAN	INS	ASAH1	DMGDH	GLDC	GCSH	IL4I1	HYKK	TDO2	PDHX	SDS	TSTD1	SECISBP2	HOGA1	GCAT	ASRGL1	MTAP	ETHE1	IDO2	HPD	ALDH7A1	IDO1	LIPT2	TPH2	LIPT1	PIP5K1C	GCDH	SLC45A2	PPARGC1A	SHMT1	SDSL	LIAS	OAZ1	OAZ2	OAZ3	ACMSD	AFMID	MED19	NAALAD2	RIMKLA	MED16	RIMKLB	MED15	PYCR1	MED18	PYCR2	MED17	TYR	MED12	GLUD1	MED11	GLUD2	BHMT	MED14	HAL	GM2A	MED13	ADI1	MED10	GPT	CSAD	ADO	DLAT	ENOPH1	MED27	AASS	MED26	BHMT2	MED29	OCA2	OAT	MED28	HAAO	MED23	HDC	MED22	ODC1	MED25	HRSP12	MED24	CARNS1	MED21	NQO1	MED20	AADAT	MANBA	PPARG	BBOX1	PPARA	FAH	AGMAT	GNMT	CCBL2	CCBL1	HNMT	SAT1	HGD	KMO	FOLH1	SMS	ASMT	MRI1	AANAT	FABP4	AGRN	AMDHD1	MPST	EEFSEC	PDHA2	PDHA1	GOT1	ADIPOQ	GOT2	AZIN2	AZIN1	QDPR	GRHPR	SEPSECS	PYCRL	TAT	AMD1	MAN2B1	GADL1	SQRDL	FTCD	DHTKD1	KYNU	PSTK	MED30	AMT	MED31	INMT	DCT	TST	CHDH	ASPG	NAT8L	ASPA	ALDH9A1	TYRP1	PDHB	SRM	CBS	PCBD1	SLC25A21	CRYM	C9orf41	SUOX	HSP90AB1	GSTZ1	TMLHE	UROC1	CTH	SARDH	SCLY	CDO1	CCNC	HSD17B10	STX1A	SDC2	CHST6	PCK1	MED13L	NCOA1	NCOA2	NCOA6	NCOA3	SREBF2	RXRA	GPC1	PARP16	PARP14	PARP10	PARP6	PARP4	PARP9	MMAA	PARP8	MUT	CACNA1D	CACNA1C	CARKD	RNLS	APOA1BP	SLC22A13	NAPRT	NAMPT	NUDT12	CHD9	CREBBP	DTYMK	AK1	IDI1	AK2	FDPS	GLRX	MVK	AK4	GGPS1	AK5	TYMS	IDI2	MSMO1	TGS1	AK7	PPAPDC2	AK8	HSD17B7	AK9	LSS	GUK1	NUDT13	ACAT2	RRM1	TM7SF2	SQLE	NME2	ARV1	CTPS2	NSDHL	NME3	PMVK	CTPS1	NME4	NME1	DCTD	CMPK1	DCTPP1	CARM1	PFAS	ATIC	PPAT	TK2	MED1	TK1	ADSL	MED8	CAD	MED9	HDHD1	MED4	ADSSL1	UMPS	GART	GMPS	MED6	ADSS	LHPP	MED7	PAICS	UCKL1	DHODH	UCK2	UCK1	CDK19	PRKAA2	PRKAG2	STK11	STS	PRKAB2	ARSJ	ARSK	TNFAIP8	ARSH	MTMR14	ARSI	GDE1	NCOR2	PIK3C2G	ARSF	NCOR1	PIK3C2B	ARSG	TNFAIP8L1	TNFAIP8L3	ARSD	TNFAIP8L2	ENPP6	ARSE	TPTE2	PLIN1	RUFY1	ARSA	MTMR1	MTMR3	SUMF2	MTMR8	SUMF1	TPST2	GDPD1	TPST1	TPTE	GDPD3	GDPD5	MTMR6	GCKR	GCK	INPP5J	INPP5K	PLEKHA1	PNPLA7	PLEKHA5	PLEKHA6	PLEKHA3	PLEKHA4	PLEKHA8	PI4KB	PNPLA6	MAN2B2	MAN2C1	CACNB2	CACNB3	CDK8	CYP46A1	AIP	CYP2U1	CMBL	CYP39A1	CYP27A1	ABCD4	ALDH3A1	POR	CES2	INPP5D	CES1	MAOB	ADH7	CYP19A1	ADH5	ADH6	CYP27B1	MARC2	MARC1	EPHX1	CYP11B2	ACOXL	CYP11B1	CYP2R1	CYP21A2	ACSS2	ADH1B	BPHL	ALDH1B1	ACSS1	CBR3	CYB5B	AOC3	NQO2	AOC1	AOC2	FMO1	FMO2	FMO3	SMARCD3	HDAC3	AADAC	SLC25A27	UCP3	UCP2	ACSL4	UCP1	ACSL3	SLC25A14	CYP51A1	KHK	SLC22A3	HELZ2	HSD3B2	HSD3B1	SLC5A8	SLC26A2	SLC26A1	PYGB	AGL	GAA	PHKB	PHKA1	PYGM	SLC9A1	PYGL	SLC5A5	PHKA2	PGM2L1	PHKG1	PHKG2	PGM2	GYG2	GYG1	AKAP5	TBL1X	SCD5	SLC7A5	ALAS2	FECH	COX15	UROS	SLC25A10	PIK3CD	CPOX	PPOX	ALAD	PIK3CB	UROD	PIK3CG	HMBS	COX10	PIK3R5	GYS1	SLC3A2	PLCG2	SLC36A4	TBL1XR1	TALDO1	TKT	RHCE	ECHS1	RHD	CHAC2	SULT1A1	ACSM3	ACSM6	GSTT2B	SULT1A4	HADH	SULT1A2	ACADS	GSTM4	THRAP3	GSTM3	GSTM2	GSTM1	SULT1B1	GSTM5	SULT1C2	SULT1C4	AKR1A1	SULT1E1	GSTA5	FAM120B	GSTA4	GSTA3	GSTA2	GSTA1	CNDP2	SULT6B1	GSTT2	GSTT1	ESD	GGCT	GCLC	NAT1	NAT2	GCLM	PODXL2	OPLAH	SULT4A1	ABHD14B	IMPAD1	ADIPOR1	BPNT1	ADIPOR2	PNMT	DDC	TH	DBH	CYP1B1	ISCA2	SLC25A37	ISCA1	SLC25A28	LYRM4	GLRX5	GLB1L	LUM	OGN	OMD	PRELP	KERA	FMOD	GNS	UGT1A4	PIK3R4	IQGAP1	RGL1	LYPLA1	GGT7	ACY3	GGT6	ACY1	MGST3	MGST1	MGST2	AKR7L	AKR7A2	AKR7A3	PPP1CC	APIP	RAP1A	MTMR4	PPP1CA	FAAH	CYP4A22	HPGDS	PTGDS	CBR1	PTGIS	FAAH2	PTGR1	PTGR2	PTGES	ALOX12B	CYP4F22	PTGS1	FAM213B	PPP2R5D	AWAT1	FDX1	ALOXE3	FDXR	FDX1L	PTGES2	EPHX2	CYP4F2	CYP4F3	B4GALNT2	AKR1C3	CYP4B1	CYP4F11	CYP4F8	CYP8B1	PIK3C3	ALOX15B	GSS	INPPL1	CA1	INPP5E	B4GAT1	CYP24A1	TIAM2	SPHK1	SMPD3	SMPD2	GBA	ACADL	ECI1	DECR1	MT-ND6	NDUFA13	MT-ND4	MT-ND5	NDUFA11	MT-CO1	FFAR1	NDUFA12	TACO1	STXBP1	NDUFA10	COX6A1	MT-ND2	MT-ND3	SACM1L	MT-ND1	SBF1	COX6B1	COX7A2L	SCO1	SCO2	UQCRC1	MT-CO2	UQCRC2	MT-CO3	TMEM126B	COX19	COX16	NDUFB10	UQCRB	NDUFB11	COX18	UQCRH	COX11	COX14	NDUFV3	CYC1	NDUFV2	NDUFV1	TRAP1	SURF1	NDUFAF6	GLYATL3	NDUFAF7	GLYATL2	UQCRQ	GLYATL1	NDUFAF4	ACSM1	NDUFAF5	ACSM2A	NDUFAF2	ACSM5	CYCS	ACSM4	NDUFAF3	GLYAT	NDUFAF1	ACSM2B	MT-CYB	COX20	COX7B	COX4I1	ETFA	TAF9	ETFB	MCEE	ECSIT	AK6	COX7C	UQCRFS1	COX8A	ACAD9	NDUFC2	NDUFC1	COQ10B	COQ10A	NDUFS8	NDUFS7	NDUFS6	NDUFS5	NDUFS4	NDUFS3	NDUFS2	NDUFS1	NDUFB9	NDUFB8	NDUFB7	NDUFB6	NDUFB5	NDUFB4	NDUFB3	ETFDH	NDUFB2	NDUFB1	UQCR11	UQCR10	COX5B	COX5A	NDUFA9	NDUFA8	NDUFA7	TIMMDC1	NDUFA6	NDUFA5	NUBPL	NDUFA4	NDUFA3	NDUFA2	NDUFA1	COX6C	LRPPRC	NDUFAB1	ATP5S	ATP5A1	ATP5C1	ATP5J	ATP5I	ATP5H	ATP5G3	ATP5G2	ATP5O	ATP5G1	ATP5L	MT-ATP6	ATP5B	CA2	ATP5E	CA4	ATP5D	ATP5F1	MT-ATP8	ATP5J2	GNA14	GNA15	GNA11	GNAQ	MECR	AHR	CYP2C19	CYP3A4	CYP2C18	CYP3A5	CYP3A7	CYP2B6	CYP2A13	CYP2D6	CYP2F1	CYP2J2	ARNT2	CYP3A7-CYP3A51P	CYP3A43	ARNT	CYP2C9	CYP2A7	CYP2A6	CYP2C8	CYP2W1	CYP2S1	CYP1A2	CYP1A1	AHRR	CYP2E1	RAB5A	FIG4	VAC14	MTMR2	PIKFYVE	MTMR9	PIK3C2A	MTM1	MTMR7	SIN3A	ITPK1	BRIP1	SAMD8	PPM1L	PPAP2C	ACOT9	SGMS2	STARD5	ACOT7	ALDH3B2	CH25H	SGPL1	SPTLC1	ACOT1	FAR1	SPTLC2	FAR2	SPTLC3	HACD1	ALDH3B1	ORMDL2	HACD3	ORMDL3	HACD2	HACD4	OSBP	SPTSSB	HSD11B1	SPTSSA	UGT8	KDSR	HSD11B2	AGMO	CERS3	CERS4	B3GALNT1	CERS5	MCAT	CERS6	PPT1	SPHK2	PPT2	SERPINA6	SPNS2	SMPD4	ORMDL1	SMPD1	SGPP2	ELOVL4	SGPP1	ELOVL6	ACER2	ELOVL7	ACER1	ACSBG1	FA2H	ACSBG2	PRKD3	VAPB	ASAH2	PPAP2B	GC	GK	ACER3	SLC27A3	PPAP2A	SLC27A5	PRKD2	DEGS1	INSIG2	PRKD1	INSIG1	DEGS2	THEM5	CSNK1G2	OSBPL9	CERS1	OSBPL7	RAPGEF3	CERS2	OSBPL6	SRD5A2	RAPGEF4	SRD5A1	OSBPL3	OSBPL2	TECRL	SLC25A1	HSD17B14	HSD17B13	HSD17B12	HSD17B11	GLTP	CERK	GBA2	ACAD11	ACAD10	ACSL6	ACSL5	UGCG	SCAP	B4GALNT1	SLC10A1	SLC10A2	CIDEA	CIDEC	AKR1B15	MOGAT3	MOGAT2	MOGAT1	TECR	HILPDA	HSD17B3	FITM1	FITM2	HSD17B8	HSD17B2	CBR4	OLAH	ESYT3	ESYT2	ESYT1	ACAA2	ENPP7	ACOT11	ACOT12	ACOT13	DHRS7B	MORC2	ACBD7	ACBD6	ACBD4	ACSF3	ACSF2	DBI	CPTP	GK2	GALC	ENTPD1	ENTPD5	LHB	TXN	CGA	CUBN	AMN	APOA2	APOA4	APOA5	ANGPTL4	CES3	SAR1B	LPL	VAMP2	GNAI1	GNAI2	APOE	NT5E	APOB	LDLR	GPIHBP1	ABCA1	MBTPS1	NR1H2	GGT1	LMBRD1	APOC3	NR1H3	DPEP2	DPEP1	DPEP3	MMACHC	APOC2	MMADHC	ALB	MBTPS2	GGT5	RAB4A	TSHB	PPP1CB	POMC	XYLB	FUT10	PPP2R1A	FUT11	PCK2	SYNJ2	B3GALT2	B3GALT1	PRKACA	MDH1	GLYCTK	FUT4	FUT6	FUT5	FUT7	SYNJ1	FUT9	SLC37A1	B3GALT4	B3GALT5	HSP90AA1	G6PC2	CRYL1	SORD	CLPS	LALBA	SLC25A11	FBP1	FBP2	PNLIP	SEC23A	LRP1	LRP2	UBA52	SEC24B	SEC24A	RAB14	UBB	SEC24D	PRKAR2B	SEC24C	UBC	RPS27A	MAOA	STAB2	GLS	PIP4K2A	PIP4K2B	NFYA	PIP4K2C	NFYB	NFYC	ASNS	SBF2	OCRL	G6PD	ST3GAL4	PTEN	ST3GAL1	ST3GAL2	ST3GAL3	GPX2	RRM2B	TMEM55B	GLS2	SUMO2	PIAS4	TXNRD1	LPGAT1	CPNE7	PITPNB	CPNE6	LCLAT1	PLB1	LIPI	LIPH	CPNE1	CPNE3	SLC35B3	MFSD2A	SLC35B2	DGAT2	PCYT2	SLC35D1	DGAT1	SLC35D2	CSNK2A1	SLCO1B1	PDZD11	STARD7	HRASLS2	CSNK2A2	SLCO1B3	PISD	PLA2G15	PLA2G16	GNPAT	PHOSPHO1	GPD2	PLA2G10	SLC5A6	GPD1	CSNK2B	PLBD1	HRASLS5	PLA2R1	SLCO1A2	PTGES3	PLA1A	CYGB	CDS1	ABHD4	ABHD3	CHAT	PLA2G3	PLD4	PLA2G5	PLD6	PLA2G6	PLD1	PLD3	PLD2	PON3	PGS1	GPX1	GPX4	PTDSS2	PTDSS1	PON2	PTPMT1	ALOX5AP	OSBPL8	PON1	TMEM86B	LTC4S	CHKB	OSBPL5	CHKA	RARRES3	STARD10	EPT1	DGAT2L6	CRLS1	PEMT	ALPI	CDS2	SLC44A5	ACHE	SLC44A3	SLC44A4	SLC44A1	SLC44A2	LPCAT1	PCTP	TAZ	OSBPL10	ACP6	FAM73A	FAM73B	B3GNT7	PLA2G12A	PLA2G4F	PCYT1B	B3GNT4	PCYT1A	B3GNT3	PLA2G4D	B3GNT2	PLA2G4B	PLA2G4C	B4GALT6	PLA2G4A	B4GALT5	GPCPD1	HADHB	HADHA	PITPNM1	PITPNM3	PITPNM2	MGLL	AGPAT5	AGPAT6	AGPAT9	PLA2G1B	AGPAT1	AGPAT2	AGPAT3	AGPAT4	AWAT2	GPAT2	CEPT1	CDIPT	PLA2G2F	BCHE	PLA2G2D	PLA2G2E	PNPLA8	AGK	MBOAT7	PLA2G2A	DDHD2	MBOAT1	MBOAT2	DDHD1	ETNPPL	GPAM	LPCAT4	ETNK2	LPCAT3	ETNK1	LPCAT2	PNPLA3	SDC4	CHPT1	GPD1L	B3GAT3	SDC3	LPIN1	LPIN2	GPC3	SDC1	LPIN3	PNPLA2	GPC2	GPC5	GPC4	GPC6	PAPSS1	IPPK	ISYNA1	INPP1	NUDT3	NUDT4	NUDT11	NUDT10	INPP5A	PPIP5K1	GLUL	PLCZ1	IMPA1	PPIP5K2	CACNA2D2	IMPA2	PLCE1	IP6K1	IP6K3	MIOX	IPMK	ITPKB	ITPKC	MINPP1	ITPKA	PLCH1	PLCH2	PLCD3	PLCD4	PLCD1	BZRAP1	CACNA1A	CACNA1E	SLC25A15	ALDH2	ARG2	SLC25A2	CPS1	ARG1	ASL	NAGS	ASS1	NMRAL1	OTC	SLC2A1	AHCYL1	NUP107	SYT5	NUP188	MLX	MARCKS	PPP2R1B	NUP214	NUP210	PRKCA	NUP93	PTPN13	NUP205	POM121	TRMT112	AAAS	NUP160	NUP85	TPR	NUP88	NUP155	NUP153	ERCC2	UGT1A1	HPGD	ALOX5	LTA4H	NUP62	NDC1	SEC13	NUP133	NUP50	NUP54	STARD3	STARD4	STARD3NL	STARD6	STAR	CYP11A1	TSPO	AKR1B1	PPP2CA	PPP2CB	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	B4GALT1	GLP1R	CYSLTR2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	GSTP1	PSMA2	PSME3	PSME4	PSME1	PSME2	GCG	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	NOSTRIN	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	GAMT	PSMB8	CKMT2	GATM	PSMB9	SLC6A8	CKM	PSMC5	CKMT1A	SLC22A2	PSMC6	CKMT1B	PSMC3	CHAC1	CKB	SLC22A1	PSMC4	PSMC1	PSMC2	SLC6A12	SLC6A11	SLC6A7	TXN2	SLC27A1	UBE2I	IDH1	CA9	NARFL	NUBP1	CIAO1	NUBP2	ADHFE1	NDOR1	D2HGDH	L2HGDH	FAM96B	MMS19	CIAPIN1	CA12	CA5B	CA3	CA5A	CA7	CA6	CA14	PIK3R3	CA13	PIK3R2	PIK3R1	NOSIP	PIK3CA	ABCC8	GPS2	THEM4	AKT1	TRIB3	FUT3	SLC46A1	HMGCL	ACSS3	BDH2	BDH1	OXCT1	OXCT2	HMGCS2	HMGCLL1	AACS	ACAT1	BLVRB	BLVRA	DDAH1	DDAH2	GYS2	ABCG2	ALDH4A1	PRODH	PRODH2	HMOX1	HMOX2	PLCB4	RBP4	TTR	RDH11	CYP4V2	HSD17B1	RBP1	LRAT	TBXAS1	IP6K2	PRSS1	PM20D1	SAMHD1	SLC2A2	PI4K2B	MTMR10	MTMR12	INPP4A	INPP4B	INPP5F	BSG	PI4K2A	PHYKPL	CTRB2	CTRB1	HSPG2	BCAN	ACOT8	EHHADH	HSD17B4	CHRM3	DECR2	ACOT6	ACAA1	ACOT4	SNAP25	DCN	ADRA2C	CD44	ADRA2A	COMT	INPP5B	PPA2	IMPDH1	IMPDH2	PAPSS2	
SEMAPHORIN INTERACTIONS%REACTOME%R-HSA-373755.1	Semaphorin interactions	PAK3	PAK2	SEMA7A	CRMP1	PLXNA2	PLXNA1	PIP5K1C	PLXNA4	PLXNA3	CDK5	PLXNB3	TREM2	RRAS	RAC1	CDK5R1	NRP1	ARHGAP35	SEMA3A	SEMA3E	ARHGEF11	ARHGEF12	ROCK1	SEMA4D	ROCK2	SEMA4A	CD72	LIMK2	LIMK1	RHOC	RHOA	MYL12B	RHOB	RND1	MYL6	ERBB2	MYH9	ITGB1	MYH14	FES	MYH11	PLXNB1	MYH10	MYL9	TYROBP	FYN	PTPRC	HSP90AB1	FARP2	GSK3B	SEMA5A	TLN1	PLXND1	ITGA1	HSP90AA1	CFL1	DPYSL4	DPYSL5	PLXNC1	DPYSL2	DPYSL3	MET	SEMA6A	PAK1	SEMA6D	
CILIUM ASSEMBLY%REACTOME%R-HSA-5617833.3	Cilium Assembly	IFT80	CSNK1E	IFT81	DYNLL1	DYNC2LI1	TUBG1	WDR60	CKAP5	TUBA4A	HSPB11	WDR34	HAUS2	HAUS1	ATAT1	AKAP9	WDR19	TTC30B	CEP63	TTC30A	TCTEX1D1	MAPRE1	TCTEX1D2	IFT20	SFI1	IFT22	IFT27	DYNLRB2	KIF17	PAFAH1B1	DYNLRB1	SDCCAG8	TTC26	DYNC1I2	TCTE3	DCTN2	IFT43	SSNA1	IFT46	DCTN3	IFT74	CLUAP1	KIF3B	HAUS8	HAUS7	PRKAR2B	KIF3C	CCT3	CEP70	BBS2	CEP72	BBS1	CEP192	CCT2	MKKS	ARL6	PCNT	CEP76	BBIP1	SSTR3	CLASP1	MCHR1	CEP78	B9D2	LZTFL1	PLK4	DYNC1H1	TTC8	ODF2	BBS10	BBS12	CEP152	ARF4	TCP1	NDE1	PLK1	BBS9	BBS7	TUBB4B	CCT8	TUBB4A	BBS5	NEDD1	BBS4	CENPJ	CDK1	CCT5	FGFR1OP	CCT4	CEP41	C2CD3	TCTN3	TCTN2	TCTN1	CEP97	CC2D2A	IQCB1	DYNLL2	KIF24	SEPT2	TMEM216	FBF1	TTBK2	TMEM67	NPHP1	NPHP4	MARK4	SCLT1	AHI1	CEP162	CEP83	B9D1	CEP89	EXOC8	EXOC7	RAB3IP	ASAP1	PKD2	PKD1	RAB11A	RHO	EXOC4	CNGA2	EXOC3	EXOC6	CNGA4	EXOC5	RAB11FIP3	EXOC2	EXOC1	CNGB1	GBF1	PDE6D	TRIP11	TNPO1	HDAC6	IFT172	CEP57	YWHAE	DYNC2H1	CETN2	RPGRIP1L	CEP164	CCP110	IFT88	ARL13B	INPP5E	ACTR1A	PCM1	SMO	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	KIF3A	PRKACA	TTC21B	NINL	IFT122	CEP290	YWHAG	RAB8A	CDK5RAP2	MKS1	UNC119B	OFD1	HSP90AA1	RP2	ARL3	KIFAP3	NPHP3	IFT52	CEP135	NPHP3-ACAD11	CYS1	IFT57	IFT140	TUBB	CEP131	HAUS4	WDR35	HAUS3	CSNK1D	HAUS6	TRAF3IP1	HAUS5	
MISSPLICED LRP5 MUTANTS HAVE ENHANCED BETA-CATENIN-DEPENDENT SIGNALING%REACTOME%R-HSA-5339717.2	Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling	DKK2	DKK4	LRP5	KREMEN1	KREMEN2	DKK1	
TWIK-RELATED ALKALINE PH ACTIVATED K+ CHANNEL (TALK)%REACTOME DATABASE ID RELEASE 74%1299361	TWIK-related alkaline pH activated K+ channel (TALK)	KCNK16	KCNK17	
ANCHORING FIBRIL FORMATION%REACTOME DATABASE ID RELEASE 74%2214320	Anchoring fibril formation	LAMB3	TLL2	BMP1	LAMA3	TLL1	COL7A1	LAMC2	
ACTIVATED NTRK2 SIGNALS THROUGH FYN%REACTOME DATABASE ID RELEASE 74%9032500	Activated NTRK2 signals through FYN	BDNF	SRC	GRIN2B	RAC1	NTRK2	DOCK3	
REGORAFENIB-RESISTANT KIT MUTANTS%REACTOME%R-HSA-9669929.1	Regorafenib-resistant KIT mutants	KIT	
NOD1 2 SIGNALING PATHWAY%REACTOME DATABASE ID RELEASE 74%168638	NOD1 2 Signaling Pathway	RIPK2	AAMP	CASP8	MAPK12	ITCH	TRAF6	UBE2V1	CYLD	TNFAIP3	BIRC2	BIRC3	UBE2N	TAB3	TAB2	NOD1	TAB1	NOD2	CASP1	CASP2	MAPK13	IRAK2	MAPK14	IRAK1	MAPK11	CASP4	MAP2K6	IKBKB	CASP9	IKBKG	CARD9	MAP3K7	CHUK	
SYNTHESIS OF IPS IN THE ER LUMEN%REACTOME%R-HSA-1855231.2	Synthesis of IPs in the ER lumen	MINPP1	
METABOLISM OF NITRIC OXIDE: NOS3 ACTIVATION AND REGULATION%REACTOME%R-HSA-202131.4	Metabolism of nitric oxide: NOS3 activation and regulation	DDAH1	DDAH2	AKT1	CAV1	SPR	DNM2	LYPLA1	ZDHHC21	NOSTRIN	WASL	HSP90AA1	CYGB	NOSIP	NOS3	
NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS%REACTOME%R-HSA-2979096.1	NOTCH2 Activation and Transmission of Signal to the Nucleus	MIB2	RPS27A	MIB1	NCSTN	NEURL1	CNTN1	UBA52	NOTCH2	PSEN2	ADAM10	DLL1	DLL4	APH1A	NEURL1B	APH1B	UBB	MDK	UBC	JAG2	PSENEN	PSEN1	JAG1	
NONSENSE MEDIATED DECAY (NMD) ENHANCED BY THE EXON JUNCTION COMPLEX (EJC)%REACTOME%R-HSA-975957.1	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	UBA52	RPS27A	PPP2CA	UPF2	UPF3A	RPL4	PPP2R2A	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	EIF4A3	RPS17	CASC3	RPS16	RPL18A	RPS19	MAGOH	RPL36AL	NCBP1	RPS18	NCBP2	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	ETF1	RPL27	RPL26	RPL29	RBM8A	RPL28	RPS4Y2	RPS4Y1	RPL39L	RPL41	UPF3B	RPL3L	MAGOHB	RPS26	RPS25	RPS28	RNPS1	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	RPLP2	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	PABPC1	RPS27L	RPS15A	RPL14	RPS3	GSPT2	RPL13	RPL15	GSPT1	RPS2	RPL18	RPL17	RPL19	RPL35A	RPL23A	DCP1A	SMG1	EIF4G1	SMG9	SMG7	SMG8	SMG5	SMG6	RPL22L1	UPF1	FAU	RPL26L1	PNRC2	PPP2R1A	
CARDIAC CONDUCTION%REACTOME DATABASE ID RELEASE 74%5576891	Cardiac conduction	NKX2-5	SCN4A	SCN4B	GATA4	AKAP9	KCNJ14	SLN	SCN7A	KCNK1	KCNK2	KCNK3	KCNK4	STIM1	ORAI2	SCN11A	ORAI1	ABCC9	SCN10A	KCNJ11	RYR1	KCNJ2	RYR2	ATP2A3	KCNJ4	ATP2A2	ATP2A1	RYR3	SLC8A3	CLIC2	KCNJ12	TRDN	ASPH	SRI	KCNK13	PLN	HIPK1	ATP2B4	ATP2B3	HIPK2	ATP2B2	CACNG6	ATP2B1	CACNG7	CACNA2D2	FGF14	RANGRF	FGF13	FGF12	FGF11	FKBP1B	TNNI3	DMPK	CAMK2B	CAMK2D	CACNB1	CACNB2	NPPC	NPR1	NPR2	CAMK2G	CORIN	SCN1B	SCN1A	TBX5	SCN3B	SCN3A	AHCYL1	WWTR1	TRPC1	SCN2A	SCN2B	CACNG8	CACNG4	ATP1B3	ATP1B2	ATP1B1	ATP1A4	SCN9A	ATP1A3	ATP1A2	KCNH2	ATP1A1	KCNK10	KCNK12	KCNK15	NOS1	NPPA	KCNE1	KCNK16	KCNE2	KCNK17	KCNE3	FXYD4	KCNK18	KCNE4	FXYD3	SCN8A	KCNQ1	KCNE5	KCNK5	FXYD2	KCNIP1	FXYD1	KCNIP2	FXYD7	KCNIP3	FXYD6	KCNIP4	CACNA1C	PRKACA	CAMK2A	KCNK6	ITPR1	KCNK7	ITPR2	ITPR3	KCNK9	KAT2B	KCND1	KCND2	KCND3	SLC8A1	SLC8A2	SCN5A	
GAP JUNCTION ASSEMBLY%REACTOME%R-HSA-190861.1	Gap junction assembly	GJB2	GJB1	GJB4	GJA1	GJB3	GJB6	GJA3	GJB5	GJA5	GJB7	GJA4	GJA9	GJA10	GJA8	GJC1	GJD2	GJD4	GJC2	GJD3	
HORMONE LIGAND-BINDING RECEPTORS%REACTOME DATABASE ID RELEASE 74%375281	Hormone ligand-binding receptors	FSHB	TSHR	LHB	GNRH2	GPHA2	GNRH1	GPHB5	FSHR	CGA	LHCGR	TSHB	GNRHR	
BETA-CATENIN PHOSPHORYLATION CASCADE%REACTOME DATABASE ID RELEASE 74%196299	Beta-catenin phosphorylation cascade	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	FRAT1	PPP2R5A	FRAT2	PPP2R5D	PPP2R5C	CTNNB1	PPP2R1B	AMER1	AXIN1	APC	
DEFECTIVE BASE EXCISION REPAIR ASSOCIATED WITH OGG1%REACTOME%R-HSA-9656249.2	Defective Base Excision Repair Associated with OGG1	OGG1	
M PHASE%REACTOME%R-HSA-68886.3	M Phase	CSNK1E	DYNLL1	TUBG1	CKAP5	TUBA4A	HAUS2	HAUS1	AKAP9	CEP63	MAPRE1	SFI1	UBA52	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	CCNB2	CCNB1	UBB	HAUS8	HAUS7	PRKAR2B	UBC	CEP70	CEP72	CEP192	RPS27A	PCNT	CEP76	CLASP1	CEP78	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	TUBB8P12	TUBB8	TUBA3E	TUBA1C	TUBB6	TUBA1B	TUBB3	TUBB1	ANKLE2	PPP2R2A	SIRT2	TUBB2B	TUBB2A	BUB1B	CDC20	BUB3	MAD2L1	CLASP2	RPS27	RCC1	XPO1	TNPO1	CSNK2A1	CSNK2A2	CSNK2B	ERCC6L	ZWILCH	CASC5	SMC3	KNTC1	MAD1L1	CDCA5	CDCA8	EML4	PDS5B	TUBGCP2	PDS5A	NCAPG	VPS4A	PMF1	NCAPH	SKA1	SKA2	TUBGCP5	TUBGCP6	DSN1	RAD21	TUBGCP3	TUBGCP4	RCC2	NDC80	TUBG2	MZT2B	ZWINT	MZT2A	STAG1	STAG2	NME7	MZT1	AHCTF1	NCAPD2	SGOL2	CHMP2B	SGOL1	NUF2	CHMP2A	WAPAL	CHMP4C	SPDL1	CHMP4B	NDEL1	NUDC	CHMP3	RANGAP1	CHMP4A	SMC1A	CHMP6	INCENP	CHMP7	BIRC5	ITGB3BP	MIS12	CENPA	AURKB	NSL1	CENPC	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	CENPN	CENPO	B9D2	CENPP	CENPQ	SPC24	SPC25	LPIN1	LPIN2	PPP1CC	LPIN3	PTTG1	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	KPNB1	RAN	RB1	NUP107	NUP188	SMC4	SMC2	GOLGA2	PPP2R1B	HIST1H2AE	HIST1H2AD	BANF1	HIST3H2BB	HIST1H2AC	HIST1H2AB	RAB2A	NUP214	NUP210	PRKCB	HIST1H2AJ	VRK1	PRKCA	LEMD3	LEMD2	NUP93	CTDNEP1	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	BLZF1	HIST1H2BD	HIST1H2BC	NUP205	POM121	H2AFB1	SET	HIST1H3J	AAAS	ARPP19	NUP160	HIST1H3A	NUP85	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	NEK9	NUP155	H3F3B	HIST1H4K	HIST1H4L	NEK6	NCAPH2	NEK7	H3F3A	NUP153	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	SETD8	DYNC1LI1	NUMA1	NCAPG2	DYNC1LI2	LMNB1	HIST2H2AC	H2AFJ	ZW10	NUP62	ENSA	UBE2D1	EMD	CDC23	KIF20A	NDC1	CDC26	CDC27	SEC13	NUP133	ANAPC7	H2AFZ	UBE2E1	H2AFX	H2AFV	MASTL	HIST2H2BE	GORASP2	HIST4H4	NUP50	ANAPC4	CNEP1R1	GORASP1	ANAPC5	NUP54	MCPH1	TUBA4B	ANAPC1	HIST1H2BN	HIST1H2BM	ANAPC2	RAB1A	ANAPC15	HIST1H2BO	ANAPC16	HIST1H2BJ	ANAPC10	HIST1H2BI	ANAPC11	HIST1H2BL	RAB1B	USO1	TUBAL3	HIST1H2BK	PPP2CA	KIF18A	HIST2H4A	PPP2CB	HIST2H4B	MAPK1	UBE2C	NUP43	RAE1	RANBP2	UBE2S	CDC16	PPP2R2D	TUBA8	HIST3H3	NUP35	NCAPD3	CLIP1	NUPL2	NUP37	KIF23	DYNLL2	KIF2A	KIF2C	KIF2B	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	DYNC1I1	PSMD2	PSMD3	PSMD1	PSMA5	CENPE	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	NIPBL	PSMD13	MAU2	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	IST1	SPAST	CC2D1B	SUMO1	UBE2I	FBXO5	LBR	ESPL1	CEP57	YWHAE	CETN2	CEP164	CCP110	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	NINL	CEP290	YWHAG	CDK5RAP2	OFD1	HSP90AA1	CEP135	TUBB	CEP131	HAUS4	HAUS3	CSNK1D	HAUS6	HAUS5	
ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS%REACTOME%R-HSA-9609736.3	Assembly and cell surface presentation of NMDA receptors	NEFL	CAMK2G	KIF17	CASK	LIN7A	LIN7C	DLG2	LIN7B	GRIN2A	LRRC7	GRIN2C	GRIN3B	GRIN3A	NBEA	APBA1	GRIN1	DLG1	DLG3	ACTN2	DLG4	CAMK2A	GRIN2B	GRIN2D	CAMK2B	CAMK2D	
TNFR1-INDUCED PROAPOPTOTIC SIGNALING%REACTOME DATABASE ID RELEASE 74%5357786	TNFR1-induced proapoptotic signaling	TRAF2	CASP8	TNFRSF1A	RIPK1	FADD	TNF	CYLD	TNFAIP3	OTUD7B	USP21	USP4	USP2	TRADD	
ADENOSINE P1 RECEPTORS%REACTOME DATABASE ID RELEASE 74%417973	Adenosine P1 receptors	ADORA2B	ADORA1	ADORA2A	ADORA3	
SCF-BETA-TRCP MEDIATED DEGRADATION OF EMI1%REACTOME%R-HSA-174113.3	SCF-beta-TrCP mediated degradation of Emi1	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	CUL1	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	FZR1	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	FBXO5	CDC20	BTRC	PSMD8	SKP1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON%REACTOME DATABASE ID RELEASE 74%936964	Activation of IRF3 IRF7 mediated by TBK1 IKK epsilon	LY96	RPS27A	TICAM1	PTPN11	TBK1	IRF3	TRAF3	CD14	IRF7	TLR4	UBA52	UBB	TANK	UBC	TICAM2	IKBKE	
ANTIGEN PROCESSING: UBIQUITINATION & PROTEASOME DEGRADATION%REACTOME DATABASE ID RELEASE 74%983168	Antigen processing: Ubiquitination & Proteasome degradation	RNF19B	RNF19A	UBE2D1	CDC23	CDC26	CDC27	SKP2	FBXO4	UBA52	ANAPC7	FBXO6	UBE2E1	TRAIP	FBXW4	FBXW5	FBXW10	FBXW7	ANAPC4	CUL1	BTBD1	ANAPC5	FBXW9	ANAPC1	UBB	FBXW2	GLMN	ANAPC2	BTBD6	UBC	RNF182	ANAPC10	ANAPC11	RNF14	RPS27A	FZR1	DTX3L	TRAF7	RBBP6	RNF25	UBE2C	FBXL3	UBE2S	CDC16	UBAC1	RNF213	TRIP12	KCTD7	UBA3	RNF41	UBE2L3	UBE2V2	CDC20	RNF217	UBE2J2	DZIP3	RNF220	UBE2B	UBE2A	FBXO27	LTN1	FBXO21	FBXO22	FBXW8	FBXO17	PSMD8	FBXO15	FBXO10	PSMD9	FBXO11	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	FBXO44	PSMD3	FBXO41	PSMD1	FBXO40	FBXO30	FBXO31	PSMA5	PSMA6	PSMA3	TRIM71	HERC2	PSMA4	PSMA1	TRIM69	PSMA2	UNKL	PSME3	UBE2D2	PSME4	FBXO32	PSME1	PSME2	CDC34	PSMD10	TRIM50	PSMB11	CUL7	PSMD12	MGRN1	PSMD11	RCHY1	PSMD14	ZNRF1	UBE2V1	PSMD13	ZNRF2	PSMB10	TRIM41	PSMA7	TRIM39	RNF34	TRIM36	PSMA8	TRIM63	TRIM37	PSMB6	TRIM32	HERC4	PSMB7	UBE2N	HERC3	PSMB4	HERC1	PSMB5	FBXO7	PSMB2	HERC6	PSMB3	FBXO9	PSMB1	PSMF1	FBXO2	SHFM1	PSMB8	PSMB9	TRIM11	PSMC5	PSMC6	PSMC3	PSMC4	FBXL8	PSMC1	PSMC2	FBXL4	FBXL7	SH3RF1	CUL5	RNF144B	GAN	KLHL2	KLHL3	KLHL9	KLHL5	UBE3C	VHL	UBE3D	UBE3A	UBE3B	UBE2Z	FBXW12	UBE4A	UBA6	UBA5	UBE2F	UBE2H	UBE2W	SOCS3	UBE2U	UBE2O	UBA1	UBE2K	UFL1	ASB13	ASB14	RNF6	ASB11	RNF7	ASB12	RNF4	ASB17	ASB18	ASB15	RBX1	ASB16	ASB10	HECW2	ANAPC13	MEX3C	NEDD4	NPEPPS	RNF111	MKRN1	UBR4	UBR2	UBR1	MIB2	UBOX5	TPP2	KBTBD13	FBXL22	ITCH	FBXL20	HECTD1	HECTD2	HECTD3	FBXL19	FBXL18	FBXL15	FBXL16	FBXL13	FBXL14	FBXL12	CBLB	FBXL5	TCEB2	DET1	TCEB1	GPR75-ASB3	UBE2L6	KBTBD6	KBTBD7	KBTBD8	HERC5	LMO7	TRIM21	LONRF1	BLMH	WWP1	THOP1	PARK2	HACE1	CUL3	LRSAM1	LRRC41	UBA7	SPSB2	SPSB1	NEDD4L	SPSB4	UBE2D4	SMURF2	SMURF1	AREL1	UBE2E3	ATG7	UBE2E2	STUB1	UBE2M	ZBTB16	ZNF645	LRR1	CCNF	KEAP1	UBE2J1	CUL2	ARIH2	LNPEP	HUWE1	MYLIP	UBE2G1	UBE2G2	KLHL41	KCTD6	KLHL42	KLHL11	KLHL13	KLHL25	KLHL21	KLHL22	KLHL20	UBE2Q1	UBE2Q2	PJA2	PJA1	UBE2R2	VPRBP	ASB8	ASB9	LNX1	ASB6	ASB7	ASB4	ASB5	UBE2D3	ASB2	ASB1	RNF115	RNF114	WSB1	RNF123	RNF126	BTRC	SOCS1	TRIM9	TRIM4	SKP1	SIAH2	RNF138	FBXW11	SIAH1	RNF130	RLIM	RBCK1	
EVASION OF OXIDATIVE STRESS INDUCED SENESCENCE DUE TO P16INK4A DEFECTS%REACTOME%R-HSA-9632693.3	Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects	CDK6	CDKN2A	CDK4	
SIGNALING BY CYTOSOLIC PDGFRA AND PDGFRB FUSION PROTEINS%REACTOME%R-HSA-9673766.1	Signaling by cytosolic PDGFRA and PDGFRB fusion proteins	FIP1L1	WDR48	STRN	
PLASMA LIPOPROTEIN CLEARANCE%REACTOME%R-HSA-8964043.1	Plasma lipoprotein clearance	APOE	APOB	LDLR	NR1H2	APOC4	APOBR	NR1H3	AP2B1	NCEH1	APOC1	HDLBP	PCSK9	AP2A1	VLDLR	AP2A2	LIPA	LIPC	LDLRAP1	AP2M1	CUBN	MYLIP	AMN	CLTC	CLTA	LSR	APOA1	SOAT1	NPC1	SOAT2	NPC2	CES3	AP2S1	
SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER%REACTOME%R-HSA-2644602.1	Signaling by NOTCH1 PEST Domain Mutants in Cancer	MIB2	MIB1	CCNC	NCSTN	NEURL1	MAML3	MAMLD1	HDAC4	UBA52	HDAC5	NOTCH1	HDAC8	HDAC9	HDAC7	CDK8	HEY1	HEY2	CUL1	UBB	UBC	HDAC10	HDAC11	RPS27A	TBL1X	MYC	SNW1	HDAC2	HDAC1	HDAC3	TBL1XR1	HDAC6	NCOR2	NCOR1	RBX1	MAML2	MAML1	KAT2B	SKP1	PSEN2	RBPJ	ADAM10	KAT2A	DLL1	HEYL	DLL4	ADAM17	APH1A	NEURL1B	APH1B	CREBBP	EP300	HES1	HES5	JAG2	PSENEN	PSEN1	JAG1	
WAX BIOSYNTHESIS%REACTOME%R-HSA-9640463.1	Wax biosynthesis	AWAT1	AWAT2	FAR1	FAR2	
INNATE IMMUNE SYSTEM%REACTOME DATABASE ID RELEASE 74%168249	Innate Immune System	IFIH1	RNF135	MAVS	SIKE1	VCP	PYGB	AGL	GAA	PYGL	SLC15A4	PGM2	MME	ATP6AP2	GYG1	ANPEP	PIK3CB	ALAD	VAV1	PLCG2	FCGR3B	PLAUR	APEH	SDCBP	CXCR1	CXCR2	POLR2E	POLR2F	POLR2H	POLR2K	POLR2L	BST1	VNN1	PANX1	LAMP2	PRKCD	MAPKAPK2	A1BG	PSAP	CYFIP2	HSPA8	NCKAP1	MAPK14	CYFIP1	MAPK11	WIPF1	ARPC1B	WIPF2	PPBP	ARPC1A	WIPF3	BRK1	WASL	ACTB	ACTG1	NCK1	ACTR3	GNS	VAV3	ACTR2	SERPINA3	ORM1	VAV2	MYH2	ELMO1	BTK	ELMO2	WAS	NCKIPSD	ORM2	NCKAP1L	WASF1	WASF2	WASF3	MYO10	QSOX1	MYO5A	ARPC4	AHSG	MYO9B	ARPC5	BAIAP2	MYO1C	CD63	ABI2	ARPC2	ARPC3	ABI1	CHRNB4	PRKACG	PRKACB	GOLGA7	PIK3R4	IQGAP1	KIR3DS1	SIRPB1	KLRK1	CLEC5A	CD300LB	SIGLEC15	PTK2	SIGLEC14	KLRC2	KIR2DS2	KIR2DS4	DSN1	NCR2	CD300E	KLRD1	DUSP4	ITCH	ITGAX	GAB2	CD47	DUSP6	VTN	DUSP7	HCK	SLC2A5	LRRC7	TLR9	MGST1	DERA	GPI	APAF1	HK3	PGAM1	MAP2K1	CASP9	VCL	ALDOC	ALDOA	RAP1B	PFKL	RAP1A	UBE2M	BCL2L1	HGSNAT	FPR1	GALNS	FPR2	PPP2R5D	ANXA2	PTGES2	PIK3C3	PTPN11	MAPK12	MLEC	CCR2	EEF1A1	EEF2	CNN2	CXCL1	PRSS3	FCN1	CFD	CRP	C1QB	COLEC11	C1QA	FCN2	COLEC10	FCN3	C1S	C1R	C4B_2	C2	C3	C4B	IGHG4	C4A	IGHG1	IGHG2	MBL2	ATF1	GZMM	MASP1	APP	ATF2	CFB	TCN1	UBE2D3	C1QC	ELK1	MAP2K3	MEF2A	CFP	MAP2K4	MEF2C	S100A1	CD180	CNPY3	VRK3	SIGIRR	MAPKAPK3	S100A9	S100A8	AGER	HSP90B1	SOCS1	IRAK1	S100A12	MAP2K7	MAP2K6	JUN	LY86	PDXK	NFKB2	MYD88	LGMN	ITGAM	HPSE	ITGB2	HMGB1	EEA1	NKIRAS1	NKIRAS2	LBP	CD36	IKBKE	GUSB	DUSP3	RIPK3	LAT2	RIPK2	DYNC1LI1	IRAK3	IRAK4	FOS	TIRAP	DNM1	DNM2	TLR1	DNM3	TRAF3	IRF7	PELI1	TLR8	TLR7	COPB1	TLR10	FABP5	BPI	TLR6	CYLD	TLR5	BIRC2	TNFAIP3	TLR3	TLR2	BIRC3	UNC93B1	PELI3	PELI2	CASP10	NOD1	NOD2	TANK	RAB6A	CASP2	MAPK9	SURF4	MAPK8	CCT2	MAPK7	MAP3K1	IGF2R	S100B	MAPK10	TNIP2	SAA1	PTPN4	TAX1BP1	CCT8	IQGAP2	TMEM173	SNAP29	UBA3	TNFRSF1B	PAFAH1B2	PGM1	ECSIT	NDUFC2	CAPZA1	CAPZA2	RAB18	ACTR10	RAB9B	ITGAL	SIRPA	LGALS3	IST1	MIF	SELL	TREM1	OLR1	FCER1G	CEACAM3	CD58	PPP3CA	PPP3CB	CAT	RETN	ITPR1	ITPR2	NEU1	ITPR3	PPP3R1	CTSA	IFNA13	IFNA14	IFNA16	IFNA17	IFNA10	GLB1	AAMP	NFATC1	ABL1	IFNA21	CTNNB1	AMPD3	IFNA5	APRT	IFNA4	PNP	IFNA7	IFNA6	IFNA1	HEXB	IFNA2	HBB	IFNA8	RAC1	RBSN	ARSB	DOCK2	DOCK1	CDC42	IFNB1	ALDH3B1	ORMDL3	ROCK1	PPIA	NFATC3	NFATC2	LIMK1	RHOA	MYH9	DEGS1	SYK	CRK	CYB5R3	BCL2	LRRFIP1	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	CR1	PTPRJ	SLC27A2	RAB4B	NRAS	PLCG1	SOS1	HRAS	C3AR1	AP2A2	TXNIP	TXN	MEFV	SERPINA1	NPC2	IL1B	VAMP8	APOB	SLC2A3	PYCARD	CYBA	RAB3A	HP	RAB31	GPR84	RAB5B	NLRP3	RAB5C	TXNDC5	PSTPIP1	CASP1	TRAPPC1	P2RX7	SUGT1	PPP2R1A	PRKACA	BTRC	MGAM	CEP290	SKP1	HSP90AA1	CHIT1	FBXW11	KCNAB2	TUBB	SNAP23	DYNLL1	UBA52	RAB10	CUL1	RAB14	UBB	UBC	TBC1D10C	RPS27A	DYNC1H1	MRE11A	TUBB4B	RAB27A	CTSZ	GDI2	CTSC	PGLYRP4	PGLYRP3	PGLYRP2	GMFG	PGLYRP1	MCEMP1	NLRX1	CDK13	RNF216	PRKDC	ATG5	FUCA2	SIGLEC9	YPEL5	SIGLEC5	TOM1	ACLY	ARL8A	REG3A	REG3G	TKFC	NIT2	PRKCSH	LEAP2	MAGT1	PIN1	RNASET2	TMBIM1	ACPP	TRIM56	CANT1	DDOST	TSPAN14	TRIM32	NLRC4	C6orf120	SLPI	IRAK2	CRISPLD2	C16orf62	TMEM63A	SYNGR1	NBEAL2	ACTR1B	FCER1A	RAP2C	RAP2B	C1orf35	GCA	CD81	C4BPA	C4BPB	C8B	C8A	SEMG1	CLU	C8G	OTUD5	CR2	CD46	CPB2	CPNE1	CPNE3	CFH	SRP14	C5AR2	CFI	PLAU	C5AR1	DGAT1	CPN2	ENPP4	CPN1	C5	PDZD11	CD4	C6	C7	CD19	C9	ADGRG3	CFHR2	CFHR1	CFHR4	CFHR3	GGH	CFHR5	CSNK2B	UBE2K	SLCO4C1	MS4A3	TNFAIP6	NCF1	HSPA6	NCF2	NCF4	CHI3L1	MS4A2	LPO	MPO	RAC2	PLD4	NOS1	NOS2	PLA2G6	NOS3	PLD1	SLC11A1	CYBB	PLD3	PLD2	PTX3	GLA	CDA	FRMPD3	CLEC10A	ARMC8	ATG12	PLAC8	RAB7A	GNLY	PLEKHO2	GRN	TMEM179B	RAB3D	RAB44	FRK	LAMP1	SLC44A2	LPCAT1	KCMF1	ILF2	RAB37	EP300	UBR4	FCAR	CREB1	PKM	FGL2	NLRC5	RAB24	VAPA	AGPAT2	CPPED1	CALML5	VAT1	MUCL1	MUC17	MUC5B	CSTB	MUC3A	PLA2G2A	EPPIN-WFDC6	MUC5AC	P2RX1	CST3	MUC1	LAIR1	MUC7	MUC12	SVIP	MUC13	MUC15	QPCT	MUC20	MUC4	MUC21	COTL1	MUC6	NLRP1	DBNL	CASP4	DCD	AIM2	DEFB4A	DEFB4B	GSN	LTF	CLEC12A	TMEM30A	RNASE6	RNASE3	SCAMP1	RNASE2	FLG2	PADI2	AZU1	LYZ	HRNR	PIGR	TMC6	SERPINB10	SERPINB12	RNASE8	RNASE7	LRG1	DEFB1	STK10	ATG7	OLFM4	S100A7	DEFA6	DEFA4	DEFA5	DEFA3	GRAP2	DEFA1	LCP2	PTPRB	FAM47E-STBD1	LRMP	CECR1	TIFA	GLIPR1	BPIFA1	BPIFA2	DHX58	ALPK1	DEFB103A	DEFB103B	ART1	COMMD9	DHX36	DEFB104B	DEFB104A	PRG2	STAT6	PRG3	BPIFB2	BPIFB1	BPIFB4	BPIFB6	CYSTM1	DEFB105A	DEFB105B	CTSH	CD33	CD53	DEFB106B	COMMD3	DEFB106A	DEFB129	DEFB128	ARG1	DEFB127	DEFB126	DEFB125	DEFB124	DEFB123	DNAJC5	DEFB107A	DEFB121	DEFB107B	PGRMC1	CREG1	KPNB1	DEFB136	HUWE1	AHCYL1	DEFB135	ISG15	CD3G	DEFB134	FCGR3A	DEFB133	FCGR1A	YES1	DEFB108B	DEFB132	DNAJC3	FGR	FCGR2A	DEFB131	CD68	OSTF1	EPPIN	CD93	ATAD3B	OSCAR	PPP2R1B	DOK3	SPTAN1	TARM1	DDX3X	TOLLIP	DYNLT1	CD59	CD55	MVP	DEFA1B	CHGA	PDAP1	S100P	ABCA13	NHLRC3	UNC13D	RNF125	CRACR2A	PRDX4	PPAPDC1A	PPAPDC1B	S100A11	GSDMD	PA2G4	SERPINB3	SERPINB1	NFAM1	SERPINB6	ASAH1	METTL7A	ITK	AGA	TXK	TEC	CARD9	ERP44	ALOX5	GHDC	LTA4H	EPX	ATP8A1	DEFB119	DEFB118	DEFB116	ZBP1	DEFB115	TBK1	UBE2D1	IRF3	DEFB114	NLRP4	DEFB113	DTX4	DEFB112	DEFB110	ATP11B	ATP11A	CLEC4A	CLEC4C	CLEC4D	JUP	CLEC4E	BRI3	CLEC7A	CLEC6A	NF2	TRPM2	S100A7A	GM2A	PPP2CA	ITLN1	PPP2CB	MAPK1	MNDA	FOLR3	PTPRN2	ATP8B4	STK11IP	FAF2	MANBA	DNASE1L1	B4GALT1	HVCN1	LILRA3	LILRB2	LILRB3	CD300A	ATP7A	ANO6	DPP7	PKP1	DNAJC13	DSC1	MAN2B1	CRISP3	HTN1	HTN3	HEBP2	CKAP4	MOSPD2	CMTM6	ADGRE5	ADGRE3	STOM	PTPRC	HSP90AB1	ITGAV	DSP	PSMD8	IKBKB	DSG1	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	DIAPH1	IKBKG	MAP3K7	CHUK	PSMA5	PRDX6	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	GSTP1	PSME3	UBE2D2	PSME4	IGKV2-28	PSME1	IGKV1-12	PSME2	IGKV3D-20	CDC34	CARD11	PSMD10	IGKV2D-28	PSMB11	TRAF6	PSMD12	IGKV4-1	IGHE	PSMD11	PSMD14	PRKCQ	UBE2V1	PSMD13	BCL10	IGKV2D-30	RASGRP2	PSMB10	MALT1	RASGRP1	PSMA7	RASGRP4	RELA	IGKV3-11	LYN	PSMA8	PSMB6	IGKV5-2	PSMB7	UBE2N	PSMB4	TAB3	PSMB5	XRCC6	TAB2	PSMB2	XRCC5	TAB1	PSMB3	TREX1	PSMB1	NLRC3	PSMF1	DDX41	IFI16	SHFM1	PSMB8	ATOX1	MB21D1	NFKB1	PSMB9	NFKBIA	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	HLA-A	NFKBIB	B2M	AP1M1	CAP1	IDH1	TICAM2	LY96	TRAF2	TICAM1	CASP8	RIPK1	CD14	FADD	TLR4	PTPN6	PDPK1	CEACAM1	CEACAM6	CEACAM8	PIK3R2	PIK3R1	PIK3CA	TYROBP	LCK	FUCA1	MAP3K8	FYN	MAP3K14	NAPRT	TCIRG1	FTH1	ATP6V1E1	ATP6V1E2	ATP6V0B	ATP6V1G1	ATP6V0E1	ATP6V1G2	CREBBP	ICAM2	ICAM3	RELB	ATP6V1B2	PAK1	ATP6V0D1	RPS6KA5	CD209	ATP6V0D2	PAK3	ATP6V0C	RAF1	ATP6V1B1	PAK2	FTL	ATP6V1A	CAND1	ATP6V0A2	ATP6V1H	ATP6V0A4	ATP6V1G3	ATP6V0E2	ATP6V1D	ATP6V1C1	NME2	HMOX2	ATP6V1C2	ATP6V0A1	ATP6V1F	LCN2	MAPK13	UBE2L6	CCR6	HERC5	TRIM25	DHX9	TRIM21	PCBP2	HLA-B	HLA-C	HLA-E	TTR	BST2	PTAFR	UBA7	CAB39	DDX58	PPIE	ARSA	LAMTOR2	LAMTOR1	LAMTOR3	CAPN1	PRSS2	ADAM10	CFL1	ADAM8	PSEN1	PRKCE	NCSTN	ELANE	PI3	CTSV	CTSS	CRCP	ACAA1	MMP25	CTSL	SNAP25	CTSK	TREM2	TIMP2	CTSG	CTSD	CTSB	POLR3GL	POLR3A	POLR3B	MMP8	MMP9	POLR3C	POLR3D	POLR3E	POLR1C	POLR3F	POLR3G	POLR3H	POLR3K	CD44	AOC1	HMHA1	NFASC	KRT1	PROS1	PRCP	ARHGAP9	IMPDH1	IMPDH2	CD177	FGB	FGA	RHOG	RHOF	FGG	F2	SERPING1	PRTN3	
LDL CLEARANCE%REACTOME%R-HSA-8964038.2	LDL clearance	AP2A2	LIPA	APOB	LDLR	LDLRAP1	AP2M1	CLTC	CLTA	LSR	AP2B1	NCEH1	SOAT1	NPC1	SOAT2	NPC2	CES3	PCSK9	AP2A1	AP2S1	
DEFECTIVE ALG14 CAUSES CONGENITAL MYASTHENIC SYNDROME (ALG14-CMS)%REACTOME DATABASE ID RELEASE 74%5633231	Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)	ALG14	ALG13	
REGULATION OF TNFR1 SIGNALING%REACTOME%R-HSA-5357905.3	Regulation of TNFR1 signaling	TRAF2	CASP8	SHARPIN	RIPK1	FADD	UBA52	GNB2L1	CYLD	TNFAIP3	BIRC2	OTUD7B	BIRC3	UBB	UBC	RPS27A	TRAF1	TNFRSF1A	TAX1BP1	RNF31	TNF	SPPL2B	SPPL2A	IKBKB	USP21	XIAP	USP4	USP2	OTULIN	CLIP3	IKBKG	CHUK	TRADD	RBCK1	
IKBKG DEFICIENCY CAUSES ANHIDROTIC ECTODERMAL DYSPLASIA WITH IMMUNODEFICIENCY (EDA-ID) (VIA TLR)%REACTOME%R-HSA-5603027.1	IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	IKBKB	IKBKG	CHUK	
LINOLEIC ACID (LA) METABOLISM%REACTOME DATABASE ID RELEASE 74%2046105	Linoleic acid (LA) metabolism	ACSL1	ELOVL1	FADS2	ABCD1	ELOVL5	ELOVL2	ELOVL3	FADS1	
ONCOGENIC MAPK SIGNALING%REACTOME%R-HSA-6802957.6	Oncogenic MAPK signaling	RAF1	MAPK3	CSK	CAMK2G	BCL2L11	AKAP9	KRAS	DUSP8	YWHAB	DUSP9	LMNA	DUSP6	NRAS	DUSP7	CNKSR2	HRAS	APBB1IP	CNKSR1	MRAS	AGK	SHOC2	MAPK1	ITGA2B	PEBP1	PPP1CC	JAK2	MAP2K1	MAP2K2	VCL	PHB	SRC	RAP1B	KIAA1549	RAP1A	MPRIP	AGTRAP	MARK3	AP3B1	SND1	PAPD7	ESRP1	KDM7A	FAM114A2	ZC3HAV1	TRAK1	PAPSS1	FXR1	FN1	ATG7	QKI	CLCN6	NF1	FAM131B	AGGF1	MAP3K11	ITGB3	ARRB1	PPP1CB	ARAF	ARRB2	DUSP16	SPRED3	FGB	SPRED2	FGA	SPRED1	TRIM24	DUSP10	VWF	CAMK2A	KSR1	FGG	TLN1	KSR2	IQGAP1	BRAP	BRAF	CAMK2B	CAMK2D	
RNA POLYMERASE II TRANSCRIPTION INITIATION%REACTOME%R-HSA-75953.2	RNA Polymerase II Transcription Initiation	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	CCNH	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	TBP	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	GTF2A1	CDK7	GTF2A2	GTF2B	ERCC3	TAF9	TAF1L	AK6	ERCC2	GTF2E1	GTF2E2	TAF7L	MNAT1	TAF9B	TAF15	TAF12	TAF13	TAF10	
CLOSTRIDIUM NEUROTOXICITY%REACTOME%R-HSA-168799.1	Clostridium neurotoxicity	STX1B	STX1A	VAMP1	SNAP25	SV2C	SYT2	SV2B	VAMP2	SV2A	SYT1	
RAB GERANYLGERANYLATION%REACTOME DATABASE ID RELEASE 74%8873719	RAB geranylgeranylation	RAB30	RAB36	RAB18	RAB40A	RAB40B	RAB9A	RAB21	RAB40C	RAB24	RAB4B	RAB9B	RABGGTB	RABGGTA	RAB10	RAB14	RAB12	RAB5A	RAB13	RAB1A	RAB6A	RAB6B	RAB1B	RAB39A	RAB3B	RAB3C	RAB42	RAB2B	RAB39B	RAB34	RAB27A	RAB27B	PTP4A2	RAB20	RAB25	RAB2A	RAB26	RAB23	RAB29	RAB15	RAB19	RAB8B	RAB17	CHML	RAB33A	RAB33B	RAB3A	RAB7B	RAB32	RAB31	RAB11B	RAB35	RAB38	RAB5B	RAB5C	CHM	RAB4A	RAB11A	RAB43	RAB41	RAB7A	RAB8A	RAB3D	RAB44	RAB22A	RAB37	
THE ROLE OF NEF IN HIV-1 REPLICATION AND DISEASE PATHOGENESIS%REACTOME DATABASE ID RELEASE 74%164952	The role of Nef in HIV-1 replication and disease pathogenesis	PAK2	CD4	ATP6V1H	AP2B1	HCK	AP2A1	LCK	AP2A2	CD28	AP1G1	FYN	PACS1	AP2M1	AP1B1	AP1S2	AP1S1	ARF1	AP1S3	HLA-A	RAC1	B2M	AP1M2	AP1M1	DOCK2	CD8B	ELMO1	AP2S1	
VLDL ASSEMBLY%REACTOME DATABASE ID RELEASE 74%8866423	VLDL assembly	APOC1	P4HB	APOB	APOC4	MTTP	
FRUCTOSE CATABOLISM%REACTOME DATABASE ID RELEASE 74%70350	Fructose catabolism	ALDH1A1	ALDOB	KHK	TKFC	GLYCTK	
PHASE 2 - PLATEAU PHASE%REACTOME DATABASE ID RELEASE 74%5576893	Phase 2 - plateau phase	CACNB2	CACNG8	CACNA1C	AKAP9	CACNG4	CACNG6	CACNG7	CACNA2D2	KCNE1	KCNE2	KCNE3	KCNE4	KCNE5	CACNB1	KCNQ1	
CELLULAR HEXOSE TRANSPORT%REACTOME DATABASE ID RELEASE 74%189200	Cellular hexose transport	SLC2A2	SLC45A3	SLC2A1	FGF21	SLC2A3	KIAA1919	SLC2A6	SLC2A7	SLC5A10	SLC5A9	SLC50A1	SLC5A4	SLC2A9	SLC2A14	SLC5A1	SLC2A4	SLC2A11	SLC2A12	SLC2A8	SLC5A2	SLC2A10	
CROSS-PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS (ENDOSOMES)%REACTOME%R-HSA-1236978.1	Cross-presentation of soluble exogenous antigens (endosomes)	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CD207	FCGR1A	FCGR1B	MRC2	MRC1	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
DEFECTIVE MISMATCH REPAIR ASSOCIATED WITH MSH2%REACTOME%R-HSA-5632928.1	Defective Mismatch Repair Associated With MSH2	MSH6	MSH2	MSH3	
RRNA MODIFICATION IN THE MITOCHONDRION%REACTOME%R-HSA-6793080.3	rRNA modification in the mitochondrion	NSUN4	RNMTL1	MTERF4	TFB1M	FTSJ2	MRM1	
DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE%REACTOME%R-HSA-2559586.3	DNA Damage Telomere Stress Induced Senescence	CDKN1A	CDKN1B	LMNB1	HIST2H2AC	H2AFJ	UBN1	H2AFZ	H2AFX	H2AFV	CCNA2	CCNA1	HIST2H2BE	CCNE2	CCNE1	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	H1F0	HIST1H2BJ	HMGA1	HIST1H2BI	HIST1H2BL	NBN	HIST1H1D	HIST1H2BK	HIST1H1E	HIST2H4A	HIST2H4B	HIST1H1A	HIST1H1B	HIST1H1C	MRE11A	CDK2	HIST3H3	HIRA	RAD50	RB1	EP400	HMGA2	CABIN1	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	TINF2	TERF1	TERF2	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	ATM	HIST1H2BD	HIST1H2BC	H2AFB1	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	ASF1A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	TP53	
METABOLISM OF COFACTORS%REACTOME%R-HSA-8978934.3	Metabolism of cofactors	AKT1	SPR	PRKG2	GCHFR	PTS	HSP90AA1	IDH1	COQ9	PDSS2	COQ7	PDSS1	COQ6	GCH1	COQ5	DHFR	COQ3	NOS3	COQ2	
PORPHYRIN METABOLISM%REACTOME%R-HSA-189445.1	Porphyrin metabolism	ABCG2	SLCO1B1	SLCO1B3	ALAS1	ALAS2	ABCC1	FECH	ABCC2	COX15	UGT1A4	UROS	GSTA1	HMOX1	CPOX	PPOX	ALAD	UROD	HMBS	ALB	COX10	HMOX2	FABP1	BLVRB	BLVRA	
PKA ACTIVATION IN GLUCAGON SIGNALLING%REACTOME%R-HSA-164378.2	PKA activation in glucagon signalling	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	ADCY9	ADCY5	PRKAR1B	PRKAR1A	PRKAR2A	PRKACA	GNAS	PRKAR2B	ADCY4	PRKACG	ADCY3	PRKACB	
CHREBP ACTIVATES METABOLIC GENE EXPRESSION%REACTOME DATABASE ID RELEASE 74%163765	ChREBP activates metabolic gene expression	AGPAT1	ACACA	MLX	ACLY	MLXIPL	ACACB	FASN	
HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS%REACTOME DATABASE ID RELEASE 74%629594	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	CHRNA5	CHRNA4	CHRNA7	CHRNA6	CHRNA9	CHRNA1	CHRNB2	CHRNA3	CHRNB4	CHRNB3	CHRNA2	
RUNX3 REGULATES P14-ARF%REACTOME DATABASE ID RELEASE 74%8951936	RUNX3 regulates p14-ARF	TGFB1	CBFB	RUNX3	BRD2	EP300	HDAC4	CCND1	KRAS	RUNX1	
SYNTHESIS OF BILE ACIDS AND BILE SALTS%REACTOME DATABASE ID RELEASE 74%192105	Synthesis of bile acids and bile salts	RXRA	OSBP	SLC27A2	ACOT8	AKR1C1	HSD17B4	AKR1C4	CYP46A1	SLC27A5	CYP39A1	OSBPL9	CYP27A1	OSBPL7	OSBPL6	ABCB11	OSBPL3	OSBPL2	AMACR	PTGIS	CYP7B1	BAAT	CYP7A1	NCOA1	ACOX2	NCOA2	NR1H4	AKR1C3	CYP8B1	CH25H	HSD3B7	AKR1D1	AKR1C2	OSBPL1A	
ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING%REACTOME%R-HSA-879415.1	Advanced glycosylation endproduct receptor signaling	PRKCSH	S100B	MAPK3	CAPZA1	CAPZA2	SAA1	MAPK1	AGER	S100A12	LGALS3	DDOST	HMGB1	APP	
ESSENTIAL PENTOSURIA%REACTOME%R-HSA-5662853.2	Essential pentosuria	DCXR	
ABACAVIR METABOLISM%REACTOME%R-HSA-2161541.3	Abacavir metabolism	ADH1A	PCK1	NT5C2	ADAL	GUK1	
DEFECTIVE F9 ACTIVATION%REACTOME DATABASE ID RELEASE 74%9673221	Defective F9 activation	GP1BA	GP5	GP9	F9	GP1BB	F11	
DEFECTIVE SLC4A4 CAUSES RENAL TUBULAR ACIDOSIS, PROXIMAL, WITH OCULAR ABNORMALITIES AND MENTAL RETARDATION (PRTA-OA)%REACTOME%R-HSA-5619054.1	Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA)	SLC4A4	
RESISTANCE OF ERBB2 KD MUTANTS TO TRASTUZUMAB%REACTOME%R-HSA-9665233.1	Resistance of ERBB2 KD mutants to trastuzumab	ERBB2	HSP90AA1	CDC37	ERBB2IP	
RESISTANCE OF ERBB2 KD MUTANTS TO OSIMERTINIB%REACTOME DATABASE ID RELEASE 74%9665247	Resistance of ERBB2 KD mutants to osimertinib	ERBB2	HSP90AA1	CDC37	ERBB2IP	
DEFECTIVE EXT2 CAUSES EXOSTOSES 2%REACTOME%R-HSA-3656237.2	Defective EXT2 causes exostoses 2	AGRN	GPC1	SDC4	SDC3	GPC3	SDC1	GPC2	GPC5	HSPG2	EXT1	GPC4	EXT2	GPC6	SDC2	
INTERACTION BETWEEN PHLDA1 AND AURKA%REACTOME%R-HSA-8854521.2	Interaction between PHLDA1 and AURKA	AURKA	PHLDA1	
MITOTIC SPINDLE CHECKPOINT%REACTOME DATABASE ID RELEASE 74%69618	Mitotic Spindle Checkpoint	RCC2	DYNC1LI1	NDC80	DYNLL1	ZWINT	DYNC1LI2	CKAP5	AHCTF1	ZW10	SGOL2	UBE2D1	SGOL1	CDC23	NUF2	CDC26	MAPRE1	CDC27	SPDL1	SEC13	NDEL1	NUP133	ANAPC7	NUDC	UBE2E1	RANGAP1	PAFAH1B1	INCENP	BIRC5	DYNC1I2	ITGB3BP	MIS12	CENPA	ANAPC4	AURKB	NSL1	ANAPC5	CENPC	BUB1	ANAPC1	CENPT	CENPU	ANAPC2	CENPF	ANAPC15	APITD1	ANAPC16	CENPH	ANAPC10	CENPI	ANAPC11	TAOK1	CENPK	CENPL	CENPM	KIF18A	PPP2CA	CENPN	CLASP1	CENPO	PPP2CB	B9D2	CENPP	DYNC1H1	CENPQ	UBE2C	NUP43	SPC24	SPC25	UBE2S	RANBP2	NDE1	PLK1	CDC16	CLIP1	NUP37	PPP1CC	DYNLL2	KIF2A	KIF2C	KIF2B	BUB1B	CDC20	BUB3	MAD2L1	CLASP2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	DYNC1I1	CENPE	RPS27	XPO1	NUP107	PPP2R1B	NUP160	NUP85	PPP2R1A	ERCC6L	ZWILCH	CASC5	KNTC1	MAD1L1	CDCA8	PMF1	SKA1	SKA2	DSN1	
MICROTUBULE-DEPENDENT TRAFFICKING OF CONNEXONS FROM GOLGI TO THE PLASMA MEMBRANE%REACTOME DATABASE ID RELEASE 74%190840	Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	GJA1	
MISCELLANEOUS SUBSTRATES%REACTOME DATABASE ID RELEASE 74%211958	Miscellaneous substrates	CYP4A22	CYP4F2	CYP2W1	CYP4F3	CYP2S1	CYP4B1	CYP4F11	CYP2U1	CYP2D6	CYP4F22	CYP3A43	CYP4A11	
LEISHMANIA PARASITE GROWTH AND SURVIVAL%REACTOME DATABASE ID RELEASE 74%9664433	Leishmania parasite growth and survival	ADCY2	ADCY1	ADCY8	ADCY7	CREB1	ADCY6	ADCY5	GNG12	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	HCK	PRKAR2B	PLCG2	GLP1R	VIPR1	VIPR2	SCT	MYH9	ADM	PTH1R	CYSLTR2	SYK	IL10	IL6	GLP2R	CD163	PLK2	PTH2R	RHBDF2	GIP	ADCYAP1	CRH	IAPP	CALCA	RAMP2	ADCYAP1R1	RAMP3	CALCRL	CALCB	GIPR	PTH	PTH2	PTHLH	ADAM17	CRHR1	GHRHR	CALCR	IGKV2-28	SCTR	IGKV1-12	IGKV3D-20	GCG	IGKV2D-28	ADM2	GHRH	IGKV4-1	VIP	RAMP1	IGKV2D-30	IGKV3-11	PLCG1	LYN	IGKV5-2	RXFP1	ADRB1	RXFP2	GPR176	ADRB2	GNAT3	HTR4	PTGDR	HTR6	HTR7	LHB	HRH2	CRHR2	DRD1	MC2R	CGA	AHCYL1	GPR15	DRD5	MC1R	CD3G	TAAR8	PRKX	GPR27	FCGR3A	TAAR9	GPR25	FCGR1A	MAPK14	YES1	GPR20	TAAR6	MC4R	FGR	GPR39	FCGR2A	FSHB	GPR32	TAAR5	TAAR2	GPBAR1	MC3R	TAAR1	FSHR	NPSR1	ADRB3	PTGER4	GPR45	PTGER2	FURIN	GNAI3	GNAI1	GNAI2	NPS	GPR150	GPHA2	P2RY11	MC5R	GPHB5	CYSLTR1	GGT1	LHCGR	DPEP2	DPEP1	DPEP3	GNAZ	GPR83	GPR84	IGHG4	AVP	IGHG1	GGT5	IGHG2	RLN2	ADORA2A	RLN3	INSL3	TSHB	PRKACG	PTGIR	PRKACB	AVPR2	GNGT1	ADORA2B	TSHR	GNGT2	POMC	ADCY9	PRKAR1B	FYN	PRKAR1A	PRKACA	PRKAR2A	ITPR1	ITPR2	ITPR3	GNAS	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	ADCY4	ADCY3	
SYNTHESIS AND PROCESSING OF GAG, GAGPOL POLYPROTEINS%REACTOME%R-HSA-174495.1	Synthesis And Processing Of GAG, GAGPOL Polyproteins	VPS37C	RPS27A	VPS37D	VPS37A	VPS37B	UBAP1	UBA52	VPS28	NMT2	UBB	TSG101	UBC	MVB12B	MVB12A	
DEFECTIVE NTHL1 SUBSTRATE BINDING%REACTOME DATABASE ID RELEASE 74%9630222	Defective NTHL1 substrate binding	NTHL1	
REUPTAKE OF GABA%REACTOME DATABASE ID RELEASE 74%888593	Reuptake of GABA	SLC6A13	SLC6A12	SLC6A11	SLC6A1	
NEUREXINS AND NEUROLIGINS%REACTOME DATABASE ID RELEASE 74%6794361	Neurexins and neuroligins	NRXN1	SHARPIN	CASK	LIN7A	LIN7C	LIN7B	STX1A	GRIN2A	GRIN2C	APBA1	GRIN1	DBNL	SIPA1L1	LRRTM3	LRRTM4	LRRTM1	LRRTM2	HOMER3	DLGAP1	DLGAP3	DLGAP2	DLGAP4	SHANK2	SHANK1	NLGN3	NLGN1	NLGN2	EPB41	STXBP1	NRXN3	NRXN2	BEGAIN	EPB41L5	EPB41L2	EPB41L3	DLG2	PDLIM5	NLGN4Y	NLGN4X	HOMER1	HOMER2	SYT7	SYT12	SYT10	APBA3	APBA2	GRM1	DLG3	DLG4	GRM5	SYT2	SYT1	EPB41L1	SYT9	GRIN2B	GRIN2D	
FGFR1 LIGAND BINDING AND ACTIVATION%REACTOME DATABASE ID RELEASE 74%190242	FGFR1 ligand binding and activation	FGF4	FGF6	FGF9	ANOS1	FGF20	FGF1	FGF23	FGF10	FGF2	FGF22	FGF3	
NON-INTEGRIN MEMBRANE-ECM INTERACTIONS%REACTOME%R-HSA-3000171.2	Non-integrin membrane-ECM interactions	NRXN1	LAMB3	ITGB5	TNC	LAMB2	LAMB1	AGRN	LAMA2	LAMA1	PRKCA	THBS1	LAMC2	LAMC1	CASK	ITGA6	TGFB1	ITGB1	VTN	DAG1	ACTN1	SDC2	ITGB3	TRAPPC4	ITGAV	SDC4	PDGFA	DDR1	FGF2	SDC3	ITGA2	PDGFB	SDC1	DDR2	HSPG2	DMD	LAMA5	LAMA3	NTN4	TTR	LAMC3	ITGB4	LAMA4	
REPLICATION OF THE SARS-COV-2 GENOME%REACTOME%R-HSA-9694686.1	Replication of the SARS-CoV-2 genome	RB1	ZCRB1	GSK3A	DDX5	GSK3B	VHL	
HCN CHANNELS%REACTOME%R-HSA-1296061.1	HCN channels	HCN1	HCN4	HCN3	HCN2	
DEFECTIVE CYP27B1 CAUSES RICKETS VITAMIN D-DEPENDENT 1A (VDDR1A)%REACTOME%R-HSA-5579014.2	Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)	CYP27B1	
DISEASES ASSOCIATED WITH N-GLYCOSYLATION OF PROTEINS%REACTOME DATABASE ID RELEASE 74%3781860	Diseases associated with N-glycosylation of proteins	MGAT2	MOGS	DPAGT1	ALG8	ALG9	ALG6	ALG14	MAN1B1	B4GALT1	ALG3	ALG13	ALG12	ALG2	ALG1	MPDU1	ALG11	RFT1	
DNA DOUBLE-STRAND BREAK REPAIR%REACTOME%R-HSA-5693532.3	DNA Double-Strand Break Repair	POLK	XRCC1	LIG3	ABL1	UBA52	H2AFX	CCNA2	CCNA1	HIST2H2BE	SMARCA5	HIST4H4	MUS81	EME1	EME2	POLH	GEN1	SLX1B	UBB	CLSPN	HIST1H2BN	SPIDR	HIST1H2BM	SLX1A	RTEL1	HIST1H2BO	RAD51AP1	UBC	HIST1H2BJ	HIST1H2BI	SLX4	XRCC2	BRCA1	HIST1H2BL	MAPK8	XRCC3	BRCA2	NBN	PALB2	RPS27A	TOP3A	HIST1H2BK	HIST2H4A	PPP4R2	HIST2H4B	TIPIN	BLM	TIMELESS	PPP4C	RBBP8	KDM4A	RPA1	RPA2	CDK2	MRE11A	HIST3H3	RAD51B	RAD50	RAD51C	RAD51	RPA3	BRIP1	EXO1	TOPBP1	ATRIP	BARD1	RMI2	RMI1	WRN	HUS1	RAD52	ERCC4	ERCC1	MDC1	RAD17	RAD1	DNA2	RAD9B	RHNO1	ATR	RAD9A	ATM	UBE2V2	PRKDC	PARP2	RAD51D	RFC5	RFC3	FEN1	PCNA	RFC4	RFC1	RFC2	POLE4	POLD3	POLD4	POLE2	POLD1	POLE3	POLD2	POLE	BABAM1	HERC2	DCLRE1C	UIMC1	RIF1	WHSC1	CHEK2	POLL	BAZ1B	CHEK1	NHEJ1	RNF168	RNF8	POLM	BRCC3	TDP2	TDP1	APBB1	TP53BP1	KDM4B	EYA1	EYA2	EYA3	BAP1	EYA4	BRE	FAM175A	SUMO2	PIAS4	UBE2N	XRCC6	XRCC5	PAXIP1	KPNA2	XRCC4	LIG4	PARP1	SUMO1	UBE2I	HIST3H2BB	SIRT6	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	RNF4	HIST1H4K	HIST1H4L	POLQ	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	PPP5C	HIST1H4E	HIST1H4F	TP53	
BASE-EXCISION REPAIR, AP SITE FORMATION%REACTOME DATABASE ID RELEASE 74%73929	Base-Excision Repair, AP Site Formation	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	HIST3H3	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	MPG	HIST1H2AJ	OGG1	TINF2	TERF1	TERF2	NEIL3	POT1	TERF2IP	HIST1H2BF	ACD	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST1H2BB	HIST1H2BA	HIST1H2BD	HIST1H2BC	H2AFB1	NEIL2	NEIL1	TDG	MBD4	SMUG1	HIST1H4K	HIST1H4L	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	NTHL1	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
PHOSPHOLIPASE C-MEDIATED CASCADE; FGFR3%REACTOME%R-HSA-5654227.2	Phospholipase C-mediated cascade; FGFR3	FGF4	FGF16	FGF9	PLCG1	FGF18	FGF20	FGF1	FGF23	FGF2	
P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1%REACTOME DATABASE ID RELEASE 74%193670	p75NTR negatively regulates cell cycle via SC1	PRDM4	HDAC2	HDAC1	NGF	NGFR	HDAC3	
G1 S-SPECIFIC TRANSCRIPTION%REACTOME DATABASE ID RELEASE 74%69205	G1 S-Specific Transcription	TYMS	LIN54	FBXO5	CCNA1	LIN37	RBL2	RBL1	CCNE1	LIN9	E2F4	E2F5	LIN52	DHFR	RBBP4	E2F6	ORC1	CDT1	CDC6	PCNA	TK1	RRM2	CDK1	CDC45	TFDP1	HDAC1	TFDP2	E2F1	POLA1	
MITOCHONDRIAL BIOGENESIS%REACTOME DATABASE ID RELEASE 74%1592230	Mitochondrial biogenesis	CREB1	MAPK12	HCFC1	TGS1	TFB1M	NR1D1	PPARGC1A	TFAM	TFB2M	POLRMT	SOD2	CARM1	GLUD1	SIRT3	GLUD2	TBL1X	CAMK4	IDH2	ATP5S	ATP5A1	ATP5C1	MED1	ATP5J	ATP5I	MAPK14	ACSS2	ATP5H	MAPK11	ATP5G3	ATP5G2	ATP5O	ATP5G1	ATP5L	MT-ATP6	NCOA1	PPARA	APOO	ATP5B	NCOA2	SAMM50	CHCHD3	NCOA6	MINOS1	ATP5E	CHCHD6	SMARCD3	HDAC3	ATP5D	HSPA9	APOOL	MTX1	C19orf70	MEF2D	MTX2	CRTC2	RXRA	DNAJC11	CRTC3	IMMT	CRTC1	ATP5F1	MTERF1	MT-ATP8	GABPA	ATP5J2	SIRT4	TBL1XR1	TMEM11	SIRT5	PPRC1	POLG2	PERM1	PRKAA2	C10orf2	SSBP1	PRKAG1	PRKAG2	PRKAG3	PRKAB2	PRKAB1	ATF2	NCOR1	MEF2C	NRF1	ALAS1	ESRRA	CYCS	HELZ2	CHD9	CREBBP	PPARGC1B	
APOBEC3G MEDIATED RESISTANCE TO HIV-1 INFECTION%REACTOME%R-HSA-180689.1	APOBEC3G mediated resistance to HIV-1 infection	PPIA	BANF1	HMGA1	PSIP1	
DEFECTIVE SLC35A3 CAUSES ARTHROGRYPOSIS, MENTAL RETARDATION, AND SEIZURES (AMRS)%REACTOME%R-HSA-5619083.1	Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS)	SLC35A3	
GP1B-IX-V ACTIVATION SIGNALLING%REACTOME DATABASE ID RELEASE 74%430116	GP1b-IX-V activation signalling	GP1BA	RAF1	GP5	GP9	FLNA	PIK3R1	YWHAZ	VWF	GP1BB	
ALKBH3 MEDIATED REVERSAL OF ALKYLATION DAMAGE%REACTOME DATABASE ID RELEASE 74%112126	ALKBH3 mediated reversal of alkylation damage	ALKBH3	ASCC1	ASCC2	ASCC3	
SIGNALING BY FGFR3 FUSIONS IN CANCER%REACTOME DATABASE ID RELEASE 74%8853334	Signaling by FGFR3 fusions in cancer	GAB1	FGFR3	NRAS	SOS1	HRAS	PIK3R1	PIK3CA	FRS2	
NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION%REACTOME%R-HSA-5250941.2	Negative epigenetic regulation of rRNA expression	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	SAP130	H2AFV	SAP30BP	DNMT1	HIST2H2BE	BAZ2A	SMARCA5	HIST4H4	DNMT3B	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	SIN3A	HDAC2	HDAC1	MBD2	POLR2E	POLR2F	POLR2H	POLR2K	POLR2L	SIN3B	TBP	POLR1C	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	SIRT1	HIST1H2AB	HIST1H2AJ	ARID4B	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	SAP30	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	SAP30L	CCNH	SAP18	H2AFB1	SUDS3	HIST1H3J	TTF1	TAF1D	ZNRD1	HIST1H3A	TAF1B	HIST1H3F	SUV39H1	TAF1C	HIST1H3G	TWISTNB	RRP8	TAF1A	HIST1H3H	UBTF	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	CD3EAP	HIST1H3E	GTF2H1	GTF2H2	H3F3B	GTF2H3	HIST1H4K	GTF2H4	HIST1H4L	GTF2H5	H3F3A	CDK7	H2BFS	ERCC3	HIST1H4A	POLR1A	HIST1H4B	POLR1B	HIST1H4H	ERCC2	HIST1H4I	POLR1E	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
FATTY ACIDS BOUND TO GPR40 (FFAR1) REGULATE INSULIN SECRETION%REACTOME DATABASE ID RELEASE 74%434316	Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	GNA11	GNAQ	PLCB3	FFAR1	PLCB1	PLCB2	GNA14	GNA15	
NUCLEAR SIGNALING BY ERBB4%REACTOME%R-HSA-1251985.5	Nuclear signaling by ERBB4	YAP1	APOE	NCSTN	SRC	PGR	TAB2	SPARC	NCOR1	HBEGF	S100B	CXCL12	STAT5A	STMN1	EREG	BTC	NRG1	PSEN2	ADAP1	NRG2	GFAP	CSN2	NRG3	APH1A	ADAM17	NRG4	APH1B	ESR1	MXD4	PSEN1	PSENEN	WWOX	
DNA DAMAGE BYPASS%REACTOME DATABASE ID RELEASE 74%73893	DNA Damage Bypass	POLK	UBA7	VCP	UBA52	RCHY1	DTL	POLH	WDR48	UBB	CUL4A	DDB1	UBC	CUL4B	RPS27A	UBE2B	UBE2L6	RBX1	USP10	POLI	USP43	REV1	RFC5	MAD2L2	KIAA0101	REV3L	RFC3	ISG15	PCNA	RPA1	RAD18	USP1	TRIM25	RFC4	RPA2	RFC1	RFC2	POLE4	POLD3	POLD4	RPA3	POLE2	UFD1L	POLD1	NPLOC4	POLE3	SPRTN	POLD2	POLE	
DEFECTIVE AMN CAUSES HEREDITARY MEGALOBLASTIC ANEMIA 1%REACTOME%R-HSA-3359462.1	Defective AMN causes hereditary megaloblastic anemia 1	GIF	CUBN	AMN	
ACTIVATION OF NA-PERMEABLE KAINATE RECEPTORS%REACTOME%R-HSA-451307.2	Activation of Na-permeable kainate receptors	GRIK1	GRIK2	
DEFECTIVE MGAT2 CAUSES MGAT2-CDG (CDG-2A)%REACTOME DATABASE ID RELEASE 74%4793952	Defective MGAT2 causes MGAT2-CDG (CDG-2a)	MGAT2	
GAMMA-CARBOXYLATION, TRANSPORT, AND AMINO-TERMINAL CLEAVAGE OF PROTEINS%REACTOME DATABASE ID RELEASE 74%159854	Gamma-carboxylation, transport, and amino-terminal cleavage of proteins	F2	F7	BGLAP	F10	PROZ	F9	GGCX	GAS6	PROC	FURIN	PROS1	
ESTROGEN BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%193144	Estrogen biosynthesis	HSD17B1	HSD17B2	CYP19A1	HSD17B14	AKR1B15	HSD17B11	
RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES%REACTOME DATABASE ID RELEASE 74%380270	Recruitment of mitotic centrosome proteins and complexes	CSNK1E	TUBGCP4	TUBG2	DYNLL1	TUBG1	MZT2B	CKAP5	MZT2A	TUBA4A	NME7	HAUS2	MZT1	HAUS1	AKAP9	CEP63	CDK11A	MAPRE1	SFI1	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	HAUS8	HAUS7	PRKAR2B	CEP70	CEP72	CEP192	PCNT	CEP76	CLASP1	CEP78	PLK4	DYNC1H1	ODF2	CEP152	NDE1	PLK1	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	FGFR1OP	CEP41	CEP57	YWHAE	CETN2	CEP164	CCP110	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	NINL	CEP290	YWHAG	CDK5RAP2	OFD1	HSP90AA1	CEP135	TUBB	CEP131	TUBGCP2	HAUS4	HAUS3	CSNK1D	TUBGCP5	HAUS6	TUBGCP6	HAUS5	TUBGCP3	
PROCESSING AND ACTIVATION OF SUMO%REACTOME DATABASE ID RELEASE 74%3215018	Processing and activation of SUMO	UBA2	SUMO1	UBE2I	SUMO3	SAE1	SUMO2	SENP5	RWDD3	SENP2	SENP1	
HEPARAN SULFATE HEPARIN (HS-GAG) METABOLISM%REACTOME DATABASE ID RELEASE 74%1638091	Heparan sulfate heparin (HS-GAG) metabolism	B4GALT7	GLB1	B3GAT2	B3GAT1	HS3ST5	HS3ST6	HS3ST4	HS3ST1	HS3ST2	SDC2	IDUA	NCAN	BGN	VCAN	IDS	DCN	SDC4	CSPG5	B3GAT3	CSPG4	SDC3	GPC3	GLB1L	SDC1	GPC2	GPC5	GPC4	GPC6	SLC35D2	AGRN	GPC1	HPSE2	XYLT2	XYLT1	HS6ST1	HS6ST2	HS6ST3	NDST2	NDST1	NAGLU	NDST4	NDST3	GLCE	HS3ST3A1	B3GALT6	HSPG2	EXT1	BCAN	EXT2	HPSE	SGSH	HS2ST1	GUSB	HS3ST3B1	
AXONAL GROWTH STIMULATION%REACTOME%R-HSA-209563.2	Axonal growth stimulation	ARHGDIA	NGF	NGFR	RHOA	
REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS%REACTOME DATABASE ID RELEASE 74%210747	Regulation of gene expression in early pancreatic precursor cells	HNF1B	PTF1A	ONECUT3	ONECUT1	NKX6-1	PDX1	FGF10	
BUDDING AND MATURATION OF HIV VIRION%REACTOME%R-HSA-162588.2	Budding and maturation of HIV virion	VPS37C	VPS37D	VPS37A	VPS37B	CHMP2B	CHMP2A	PPIA	CHMP4C	CHMP4B	UBAP1	CHMP3	UBA52	NEDD4L	CHMP4A	CHMP6	CHMP7	VPS28	CHMP5	PDCD6IP	UBB	UBC	RPS27A	TSG101	VPS4B	VPS4A	MVB12B	MVB12A	VTA1	
NEUROFASCIN INTERACTIONS%REACTOME%R-HSA-447043.1	Neurofascin interactions	NRCAM	CNTN1	ANK1	CNTNAP1	SDCBP	NFASC	DCX	
MET INTERACTS WITH TNS PROTEINS%REACTOME DATABASE ID RELEASE 74%8875513	MET interacts with TNS proteins	ITGB1	TNS4	TNS3	HGF	MET	
TRNA AMINOACYLATION%REACTOME%R-HSA-379724.1	tRNA Aminoacylation	YARS	CARS	DARS	WARS	VARS	TARS	SARS	EPRS	NARS	AIMP1	AIMP2	QARS	KARS	PPA1	LARS	PPA2	MARS	RARS	GARS	HARS	IARS	RARS2	EEF1E1	AARS2	FARSA	MARS2	FARSB	PARS2	AARS	DARS2	YARS2	HARS2	WARS2	FARS2	LARS2	SARS2	NARS2	IARS2	TARS2	VARS2	CARS2	EARS2	
TALDO1 DEFICIENCY: FAILED CONVERSION OF FRU(6)P, E4P TO SH7P, GA3P%REACTOME DATABASE ID RELEASE 74%6791462	TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P	TALDO1	
LEUKOTRIENE RECEPTORS%REACTOME DATABASE ID RELEASE 74%391906	Leukotriene receptors	GPR17	LTB4R	CYSLTR1	LTB4R2	CYSLTR2	
DEFECTIVE ABCA12 CAUSES ARCI4B%REACTOME DATABASE ID RELEASE 74%5682294	Defective ABCA12 causes ARCI4B	ABCA12	
DEFECTIVE ABCC6 CAUSES PXE%REACTOME%R-HSA-5690338.2	Defective ABCC6 causes PXE	ABCC6	
DNA REPLICATION INITIATION%REACTOME%R-HSA-68952.2	DNA replication initiation	POLA2	POLE2	POLE3	PRIM2	POLE	PRIM1	POLE4	POLA1	
ABERRANT REGULATION OF MITOTIC CELL CYCLE DUE TO RB1 DEFECTS%REACTOME%R-HSA-9687139.2	Aberrant regulation of mitotic cell cycle due to RB1 defects	CDKN1A	CDKN1B	E2F3	UBE2D1	CDC23	CDC26	CDC27	SKP2	ANAPC7	UBE2E1	CCND3	CCNE2	CCNE1	ANAPC4	CDKN1C	ANAPC5	ANAPC1	ANAPC2	ANAPC15	ANAPC16	E2F2	ANAPC10	ANAPC11	FZR1	CCND2	CDK6	UBE2C	UBE2S	CDC16	CDK2	CCND1	CDK4	RB1	TFDP1	TFDP2	E2F1	
G-PROTEIN MEDIATED EVENTS%REACTOME DATABASE ID RELEASE 74%112040	G-protein mediated events	ADCY2	ADCY1	ADCY8	ADCY7	CREB1	ADCY6	CAMK2G	PLA2G4A	ADCY5	GNAO1	GNAT1	PRKCG	PLCB4	PDE1C	PDE1B	PDE1A	GNAL	ADRBK1	PRKCD	CAMKK1	CAMKK2	PRKAR2B	GNAT3	KPNA2	NBEA	CAMK4	MAPK1	AHCYL1	PRKX	GNAI3	GNAI1	GNAI2	PRKCA	GNAZ	PRKACG	PRKACB	GNAT2	ADCY9	PRKAR1B	PRKAR1A	PLCB3	PLCB1	PLCB2	PRKACA	CAMK2A	PRKAR2A	ITPR1	ITPR2	ITPR3	CAMK2B	ADCY4	CAMK2D	ADCY3	
INTERLEUKIN-23 SIGNALING%REACTOME%R-HSA-9020933.1	Interleukin-23 signaling	STAT4	P4HB	IL23R	IL12B	JAK2	IL12RB1	IL23A	TYK2	STAT3	
MATURATION OF NUCLEOPROTEIN%REACTOME DATABASE ID RELEASE 74%9683610	Maturation of nucleoprotein	SUMO1	UBE2I	PARP16	PARP14	PARP10	PARP6	PARP4	GSK3B	PARP9	PARP8	
EXTRINSIC PATHWAY OF FIBRIN CLOT FORMATION%REACTOME%R-HSA-140834.2	Extrinsic Pathway of Fibrin Clot Formation	F3	F7	F10	F9	TFPI	
BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS (SPMS)%REACTOME%R-HSA-9018678.3	Biosynthesis of specialized proresolving mediators (SPMs)	LTA4H	CYP2C9	ALOX5AP	PTGS2	CYP2C8	LTC4S	CYP1A2	CYP1A1	PTGR1	CYP2E1	EPHX2	CYP3A4	CYP2D6	GSTM4	ALOX15	HPGD	ALOX12	ALOX5	
TIGHT JUNCTION INTERACTIONS%REACTOME DATABASE ID RELEASE 74%420029	Tight junction interactions	CRB3	F11R	CLDN2	CLDN1	CLDN22	CLDN20	CLDN23	CLDN11	CLDN6	CLDN10	CLDN4	CLDN3	CLDN15	CLDN14	CLDN9	CLDN8	PARD3	CLDN12	CLDN7	CLDN19	CLDN18	CLDN17	CLDN5	CLDN16	PARD6G	PRKCI	PARD6B	PARD6A	MPP5	INADL	
ACTIVATION OF C3 AND C5%REACTOME%R-HSA-174577.3	Activation of C3 and C5	C4B_2	C2	C3	C4B	C5	C4A	CFB	
UPTAKE AND ACTIONS OF BACTERIAL TOXINS%REACTOME%R-HSA-5339562.2	Uptake and actions of bacterial toxins	MAP2K4	HSP90AB1	CD9	GUCY2C	EEF2	PDZD3	SYT2	SYT1	MAP2K7	HSP90AA1	STX1B	PDCD6IP	TXNRD1	STX1A	MAP2K1	VAMP1	SNAP25	MAP2K2	FURIN	SV2C	SV2B	VAMP2	SV2A	HBEGF	
ER-PHAGOSOME PATHWAY%REACTOME DATABASE ID RELEASE 74%1236974	ER-Phagosome pathway	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	TIRAP	PSME3	PSME4	TAP2	PSME1	TLR1	PSME2	TAP1	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	TLR6	PSMB10	PSMA7	TLR2	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PDIA3	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	CALR	HLA-A	B2M	HLA-B	HLA-C	HLA-F	HLA-G	HLA-E	VAMP8	BTK	LY96	STX4	SEC61A2	SEC61A1	CD14	TLR4	TAPBP	SEC22B	VAMP3	SEC61G	SEC61B	PSMD8	IKBKB	PSMD9	MYD88	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	SNAP23	PSMD3	PSMD1	IKBKG	CD36	CHUK	PSMA5	
P75 NTR RECEPTOR-MEDIATED SIGNALLING%REACTOME%R-HSA-193704.1	p75 NTR receptor-mediated signalling	SQSTM1	RIPK2	ARHGEF26	MAGED1	RTN4	NCSTN	ABR	BCL2L11	NGEF	ECT2	ARHGEF33	NGFR	TRAF6	ARHGEF35	UBA52	ARHGEF37	ARHGEF39	ARHGEF38	ITGB3BP	NET1	RELA	ARHGEF10L	AATF	SOS1	SMPD2	UBB	AKAP13	CASP3	MCF2L	CASP2	UBC	ARHGEF10	PLEKHG2	MAPK8	TRIO	ARHGEF15	PLEKHG5	RPS27A	NFKB1	ARHGEF17	ARHGEF16	KALRN	NFKBIA	ARHGEF19	ARHGEF18	NGF	ARHGEF9	ARHGEF3	ARHGEF4	RAC1	ARHGEF1	ARHGEF2	ARHGEF5	ARHGEF6	VAV1	FGD1	FGD2	GNA13	FGD3	HDAC2	FGD4	HDAC1	LINGO1	VAV3	SOS2	MCF2	VAV2	HDAC3	ARHGEF7	ARHGEF11	ARHGEF12	MAG	RHOA	YWHAE	BAD	RASGRF2	TIAM1	IRAK1	PRDM4	PSEN2	IKBKB	PREX1	MYD88	ARHGDIA	ARHGEF40	ADAM17	APH1A	ITSN1	PRKCI	APH1B	OMG	TIAM2	NGFRAP1	PSENEN	OBSCN	PSEN1	
INLA-MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS%REACTOME DATABASE ID RELEASE 74%8876493	InlA-mediated entry of Listeria monocytogenes into host cells	RPS27A	CBLL1	CTNND1	CTNNB1	SRC	CDH1	UBB	UBC	UBA52	
MTB IRON ASSIMILATION BY CHELATION%REACTOME DATABASE ID RELEASE 74%1222449	Mtb iron assimilation by chelation	LTF	
RESOLUTION OF D-LOOP STRUCTURES THROUGH SYNTHESIS-DEPENDENT STRAND ANNEALING (SDSA)%REACTOME DATABASE ID RELEASE 74%5693554	Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	DNA2	KAT5	ATM	RTEL1	RAD51AP1	BRCA1	XRCC2	BRCA2	XRCC3	NBN	PALB2	TOP3A	RAD51D	BLM	RBBP8	MRE11A	RAD51B	RAD50	RAD51C	RAD51	BRIP1	EXO1	BARD1	RMI2	WRN	RMI1	
PD-1 SIGNALING%REACTOME DATABASE ID RELEASE 74%389948	PD-1 signaling	HLA-DQA1	TRAV19	HLA-DRB5	CSK	HLA-DRB4	CD4	HLA-DPB1	PDCD1	PTPN11	HLA-DRA	HLA-DRB3	HLA-DRB1	CD3G	PTPN6	CD3E	CD3D	HLA-DPA1	PDCD1LG2	HLA-DQB2	HLA-DQB1	CD274	LCK	HLA-DQA2	
CD28 CO-STIMULATION%REACTOME%R-HSA-389356.2	CD28 co-stimulation	PAK3	PAK2	PRR5	CD86	PDPK1	MAPKAP1	LYN	CD80	PIK3R3	PIK3R2	PIK3R1	MTOR	PIK3CA	LCK	AKT2	GRAP2	AKT3	MLST8	CD28	THEM4	AKT1	TRIB3	MAP3K8	FYN	RICTOR	MAP3K14	RAC1	YES1	VAV1	CDC42	PAK1	
FCGAMMA RECEPTOR (FCGR) DEPENDENT PHAGOCYTOSIS%REACTOME%R-HSA-2029480.1	Fcgamma receptor (FCGR) dependent phagocytosis	MAPK3	PRKCE	IGKV2-28	IGKV1-12	IGKV3D-20	IGKV2D-28	ABL1	IGKV4-1	IGKV2D-30	IGKV3-11	PLCG1	LYN	IGKV5-2	PRKCD	HCK	NF2	MAPK1	AHCYL1	CD3G	CYFIP2	NCKAP1	FCGR3A	CYFIP1	RAC1	FCGR1A	WIPF1	YES1	ARPC1B	PIK3CB	FGR	WIPF2	FCGR2A	ARPC1A	VAV1	WIPF3	BRK1	WASL	ACTB	DOCK1	ACTG1	PLCG2	NCK1	ACTR3	VAV3	ACTR2	CDC42	VAV2	MYH2	ELMO1	BTK	ELMO2	WAS	NCKIPSD	NCKAP1L	WASF1	WASF2	WASF3	MYO10	MYO5A	ARPC4	MYO9B	ARPC5	LIMK1	BAIAP2	MYO1C	ABI2	ARPC2	ARPC3	ABI1	MYH9	IGHG4	IGHG1	IGHG2	PIK3R2	PLD4	PIK3R1	SYK	PIK3CA	CRK	PLA2G6	PLD1	PLD3	PLD2	FYN	HSP90AB1	PPAPDC1A	PPAPDC1B	ITPR1	ITPR2	ITPR3	HSP90AA1	CFL1	PTK2	PAK1	
GLYCINE DEGRADATION%REACTOME DATABASE ID RELEASE 74%6783984	Glycine degradation	DLD	AMT	GLDC	GCSH	
CA ACTIVATED K+ CHANNELS%REACTOME%R-HSA-1296052.1	Ca activated K+ channels	KCNMB1	KCNMB2	KCNMB3	KCNN1	KCNMB4	KCNN2	KCNMA1	KCNN3	KCNN4	
SORAFENIB-RESISTANT KIT MUTANTS%REACTOME DATABASE ID RELEASE 74%9669936	Sorafenib-resistant KIT mutants	KIT	
CHONDROITIN SULFATE BIOSYNTHESIS%REACTOME DATABASE ID RELEASE 74%2022870	Chondroitin sulfate biosynthesis	CHST7	CHPF2	NCAN	CSGALNACT1	CHST3	BGN	CHSY1	CSGALNACT2	VCAN	DCN	CHSY3	CHST11	CSPG5	CHST12	CSPG4	CHST15	CHST13	BCAN	CHPF	
NEGATIVE REGULATION OF TCF-DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS%REACTOME%R-HSA-3772470.2	Negative regulation of TCF-dependent signaling by WNT ligand antagonists	WNT3A	SOST	WNT9A	LRP5	LRP6	WNT5A	DKK1	DKK2	DKK4	SFRP1	SFRP2	KREMEN1	KREMEN2	WIF1	WNT4	
TERMINAL PATHWAY OF COMPLEMENT%REACTOME%R-HSA-166665.3	Terminal pathway of complement	C5	C6	C7	C8B	C9	C8A	CLU	C8G	
MRNA EDITING: A TO I CONVERSION%REACTOME%R-HSA-75064.2	mRNA Editing: A to I Conversion	ADAR	ADARB1	
COPII-MEDIATED VESICLE TRANSPORT%REACTOME%R-HSA-204005.4	COPII-mediated vesicle transport	AREG	SEC22A	SEC22C	TRAPPC6B	SEC23A	TFG	SEC13	PREB	TMED10	SEC24B	SEC24A	GRIA1	GORASP1	SEC31A	RAB1A	SEC24D	SEC24C	RAB1B	USO1	LMAN1L	LMAN2L	SCFD1	SERPINA1	GOLGA2	TMED2	SAR1B	CTSZ	LMAN1	CTSC	LMAN2	TRAPPC10	CD59	STX17	COL7A1	SEC23IP	FOLR1	BET1	SEC22B	ANKRD28	TRAPPC2	SEC16B	TRAPPC2L	NAPA	TRAPPC3	NAPB	TRAPPC1	TBC1D20	TRAPPC4	SEC16A	GOSR2	TRAPPC5	NAPG	TRAPPC9	CNIH1	TGFA	F5	STX5	YKT6	NSF	CNIH2	F8	CNIH3	MCFD2	PPP6C	CSNK1D	PPP6R1	PPP6R3	TRAPPC6A	
PRE-MRNA SPLICING%REACTOME%R-HSA-72163.2	pre-mRNA splicing	SKIV2L2	CPSF7	CPSF1	CPSF3	CSTF3	CSTF2	CPSF2	HNRNPU	CSTF2T	HNRNPR	WDR33	CCAR1	NUDT21	SNRPD2	FIP1L1	SNRPD1	CLP1	SNRPD3	PCF11	PAPOLA	SRRM2	AQR	CSTF1	SYMPK	CRNKL1	CD2BP2	SF1	DHX9	PCBP1	PCBP2	PRPF38A	HNRNPL	HNRNPM	HNRNPK	HNRNPF	HNRNPD	HNRNPC	SUGP1	PRPF19	PQBP1	DHX15	DHX16	PRPF40A	GCFC2	HNRNPH1	HNRNPH2	SF3B4	SF3B5	SF3B2	SF3B3	SF3B6	SRRT	SRSF10	SF3B1	SF3A3	SF3A1	SF3A2	XAB2	PHF5A	HNRNPA2B1	PRPF31	CWC25	CWC27	EFTUD2	CWC22	TXNL4A	SNRPN	WBP11	PRPF4	PRPF6	HNRNPUL1	EIF4A3	PRPF3	POLR2A	CASC3	SNRPG	POLR2B	SNRNP27	POLR2C	MAGOH	PPIE	PPIH	NCBP1	POLR2D	SNRPE	NCBP2	SNRPF	POLR2E	POLR2F	SNRPC	SNRNP200	POLR2G	SNRPA	POLR2H	CDC40	SNRPB	POLR2I	SRRM1	DDX5	POLR2J	PRPF8	POLR2K	FUS	POLR2L	CWC15	CHERP	SRSF2	LSM8	SRSF3	ISY1	SRSF4	DDX46	SRSF5	DDX42	SRSF6	PPWD1	YBX1	SRSF7	USP39	ELAVL2	SLU7	SRSF9	PTBP1	SART1	RBM8A	SNRNP70	CTNNBL1	BCAS2	SRSF1	RBM5	U2AF1	RBM17	U2AF1L4	BUD31	TFIP11	PLRG1	U2AF2	DHX38	SYF2	SNRPA1	SRSF11	DNAJC8	UPF3B	RBM22	MAGOHB	PRCC	WBP4	RNPS1	DDX23	PUF60	TRA2B	SNRPB2	HNRNPA1	SMNDC1	HNRNPA0	PPIL1	HNRNPA3	GPKOW	CDC5L	U2SURP	SNRNP40	ELAVL1	PPIL3	PPIL4	RBMX	PPIL6	LSM5	LSM4	LSM3	LSM2	GTF2F1	GTF2F2	LSM7	LSM6	CPSF4	HSPA8	SNW1	PABPN1	NHP2L1	
DEFECTIVE SLC29A3 CAUSES HISTIOCYTOSIS-LYMPHADENOPATHY PLUS SYNDROME (HLAS)%REACTOME%R-HSA-5619063.2	Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS)	SLC29A3	
SIGNALING BY FGFR2 FUSIONS%REACTOME%R-HSA-8853333.1	Signaling by FGFR2 fusions	FGFR2	
BIOGENIC AMINES ARE OXIDATIVELY DEAMINATED TO ALDEHYDES BY MAOA AND MAOB%REACTOME DATABASE ID RELEASE 74%141333	Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB	MAOB	MAOA	
PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS%REACTOME DATABASE ID RELEASE 74%2393930	Phosphate bond hydrolysis by NUDT proteins	NUDT16	NUDT15	NUDT5	ADPRM	
BIOSYNTHESIS OF E-SERIES 18(S)-RESOLVINS%REACTOME DATABASE ID RELEASE 74%9018896	Biosynthesis of E-series 18(S)-resolvins	LTA4H	ALOX15	HPGD	ALOX5	
DARPP-32 EVENTS%REACTOME%R-HSA-180024.3	DARPP-32 events	PPP3CC	PDE4B	PPP3CA	PDE4A	PDE4D	PPP2CA	PPP3CB	PDE4C	PPP2CB	PPP1R1B	PRKAR1B	PPP2R1A	PRKAR1A	PRKAR2A	PRKACA	PPP2R5D	PPP1CA	PPP3R1	CDK5	PPP2R1B	PRKAR2B	PRKACG	PRKACB	
ACTIVATION OF BIM AND TRANSLOCATION TO MITOCHONDRIA%REACTOME%R-HSA-111446.2	Activation of BIM and translocation to mitochondria	DYNLL1	BCL2L11	MAPK8	
SUMO E3 LIGASES SUMOYLATE TARGET PROTEINS%REACTOME DATABASE ID RELEASE 74%3108232	SUMO E3 ligases SUMOylate target proteins	PHC2	STAG1	STAG2	PHC1	NUP62	NDC1	SEC13	NUP133	PHC3	RANGAP1	CBX5	SMC1A	PPARGC1A	INCENP	DNMT1	BIRC5	HIST4H4	DNMT3B	NUP50	AURKB	AURKA	NUP54	NRIP1	NOP58	RING1	BRCA1	ZNF350	SUZ12	XPC	HIST2H4A	HIST2H4B	BLM	NUP43	RAE1	RANBP2	RPA1	SIN3A	NUP35	NUPL2	NUP37	SATB1	HNRNPK	PPARG	PPARA	HNRNPC	HDAC2	HDAC1	PARK7	WRN	TFAP2B	RAD52	TFAP2C	MDC1	SP100	RORA	DAXX	PGR	ING2	NCOR2	EID3	RARA	PML	CDKN2A	MBD1	DDX5	PCNA	HIPK2	SP3	PCGF2	FOXL2	NSMCE4A	UHRF2	NSMCE2	NSMCE1	ZBED1	IKBKG	HERC2	DNMT3A	RNF168	MKL1	TP53BP1	MDM2	HDAC4	SMC5	SMC6	TOP2A	HDAC7	DDX17	TOP2B	RELA	SUMO3	SUMO2	PIAS4	ZNF131	NPM1	PIAS3	TOP1	NDNL2	NFKBIA	XRCC4	PARP1	MITF	NR3C2	HIC1	TRIM28	NUP107	SUMO1	NUP188	NCOA1	UBE2I	NCOA2	ESR1	CBX8	VHL	CBX4	CBX2	NR5A1	NUP214	L3MBTL2	NR4A2	NUP210	RXRA	THRB	NR3C1	NUP93	NR1H2	TOPORS	BMI1	NR2C1	SATB2	PIAS1	NUP205	POM121	CHD3	AAAS	NUP160	MTA1	NUP85	TPR	CETN2	NUP88	VDR	TDG	NUP155	HIST1H4K	SAFB	RNF2	HIST1H4L	TRIM27	AR	NUP153	NFKB2	SMC3	HIST1H4A	HIST1H4B	HIST1H4H	CDCA8	HIST1H4I	CREBBP	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	CTBP1	HIST1H4F	IKBKE	TP53	RAD21	
TLR3 DEFICIENCY - HSE%REACTOME%R-HSA-5602410.1	TLR3 deficiency - HSE	TLR3	
TRANSPORT OF HA TRIMER, NA TETRAMER AND M2 TETRAMER FROM THE ENDOPLASMIC RETICULUM TO THE GOLGI APPARATUS%REACTOME%R-HSA-168874.3	Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus	
TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS%REACTOME DATABASE ID RELEASE 74%5669034	TNFs bind their physiological receptors	TNFSF14	TNFSF15	TNFRSF9	FASLG	TNFSF4	CD27	TNFSF9	TNFSF8	EDA	TNFRSF13B	EDA2R	TNFSF13B	EDARADD	TNFRSF1B	LTA	TNFRSF25	CD70	TNFRSF18	TNFRSF1A	TNFSF13	TNFRSF6B	TNFSF11	TNFRSF8	TNFRSF4	EDAR	TNFRSF11B	TNFRSF17	TNFRSF14	TNFSF18	
LONG-TERM POTENTIATION%REACTOME DATABASE ID RELEASE 74%9620244	Long-term potentiation	GRIN1	NEFL	CAMK2G	SRC	DLG1	DLG3	ACTN2	DLG4	CAMK2A	NRGN	NRG1	GRIA1	GRIA2	DLG2	GRIN2B	GRIN2A	GRIN2D	LRRC7	CAMK2B	GRIN2C	CAMK2D	
DASATINIB-RESISTANT KIT MUTANTS%REACTOME DATABASE ID RELEASE 74%9669914	Dasatinib-resistant KIT mutants	KIT	
ATF6 (ATF6-ALPHA) ACTIVATES CHAPERONES%REACTOME DATABASE ID RELEASE 74%381033	ATF6 (ATF6-alpha) activates chaperones	ATF4	MBTPS2	MBTPS1	HSPA5	NFYA	CALR	NFYB	NFYC	HSP90B1	DDIT3	ATF6	
DEFECTS IN BIOTIN (BTN) METABOLISM%REACTOME%R-HSA-3323169.1	Defects in biotin (Btn) metabolism	MCCC1	ACACA	BTD	PCCA	PCCB	HLCS	PC	MCCC2	
SIGNAL TRANSDUCTION BY L1%REACTOME DATABASE ID RELEASE 74%445144	Signal transduction by L1	MAPK3	CSNK2A1	NCAM1	CSNK2A2	MAPK1	ITGA2B	ITGAV	RAC1	CSNK2B	NRP1	EGFR	ITGB1	L1CAM	ITGA5	ITGA9	MAP2K1	VAV2	MAP2K2	PAK1	ITGB3	
ACTIVATION OF MATRIX METALLOPROTEINASES%REACTOME%R-HSA-1592389.1	Activation of Matrix Metalloproteinases	CMA1	ELANE	KLKB1	COL18A1	CTSV	MMP25	MMP24	CTSK	TIMP2	PRSS1	CTSG	TIMP1	TPSAB1	MMP7	MMP1	MMP2	MMP3	MMP8	MMP9	MMP10	PRSS2	MMP11	MMP14	CTRB2	MMP13	MMP16	CTRB1	MMP15	MMP17	PLG	FURIN	SPOCK3	KLK2	
INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA%REACTOME%R-HSA-2534343.2	Interaction With Cumulus Cells And The Zona Pellucida	ADAM30	ADAM2	B4GALT1	ZP1	ADAM21	ZP3	ADAM20	ZP2	SPAM1	OVGP1	ZP4	
SUMOYLATION OF INTRACELLULAR RECEPTORS%REACTOME DATABASE ID RELEASE 74%4090294	SUMOylation of intracellular receptors	NR4A2	RARA	RXRA	THRB	VDR	NR3C1	NR1H2	RORA	HDAC4	NR2C1	PGR	NR3C2	AR	PIAS1	SUMO1	PPARG	PPARA	UBE2I	SUMO3	SUMO2	PIAS4	PIAS3	ESR1	NR5A1	
DEGRADATION OF GABA%REACTOME DATABASE ID RELEASE 74%916853	Degradation of GABA	ABAT	ALDH5A1	
PHOSPHOLIPASE C-MEDIATED CASCADE: FGFR1%REACTOME%R-HSA-5654219.2	Phospholipase C-mediated cascade: FGFR1	FGF4	FGF6	FGF9	PLCG1	FGF20	FGF1	FGF23	FGF10	FGF2	FGF22	FGF3	
IMATINIB-RESISTANT KIT MUTANTS%REACTOME DATABASE ID RELEASE 74%9669917	Imatinib-resistant KIT mutants	KIT	
MASTL FACILITATES MITOTIC PROGRESSION%REACTOME%R-HSA-2465910.2	MASTL Facilitates Mitotic Progression	PPP2CA	PPP2CB	CCNB1	PPP2R1A	ENSA	PPP2R1B	PPP2R2D	ARPP19	CDK1	MASTL	
PROCESSING OF CAPPED INTRONLESS PRE-MRNA%REACTOME DATABASE ID RELEASE 74%75067	Processing of Capped Intronless Pre-mRNA	LSM10	LSM11	CPSF7	CPSF1	CPSF3	CSTF3	CSTF2	CPSF2	SNRPG	CSTF2T	WDR33	NCBP1	NUDT21	FIP1L1	NCBP2	SNRPE	CLP1	SNRPF	PCF11	SNRPD3	PAPOLA	CSTF1	ZNF473	SYMPK	CPSF4	SNRPB	SLBP	PABPN1	
DEFECTIVE CYP11B2 CAUSES CORTICOSTERONE METHYLOXIDASE 1 DEFICIENCY (CMO-1 DEFICIENCY)%REACTOME%R-HSA-5579009.2	Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency)	CYP11B2	
PI3K EVENTS IN ERBB4 SIGNALING%REACTOME DATABASE ID RELEASE 74%1250342	PI3K events in ERBB4 signaling	NRG1	NRG2	NRG3	NRG4	PIK3R1	PIK3CA	EREG	BTC	HBEGF	
APEX1-INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY%REACTOME DATABASE ID RELEASE 74%5649702	APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	POLB	NEIL2	OGG1	XRCC1	NEIL1	LIG3	PNKP	
WNT5A-DEPENDENT INTERNALIZATION OF FZD2, FZD5 AND ROR2%REACTOME DATABASE ID RELEASE 74%5140745	WNT5A-dependent internalization of FZD2, FZD5 and ROR2	FZD2	AP2A2	FZD5	ROR1	ROR2	WNT5A	AP2M1	CLTC	CLTA	AP2B1	CLTB	AP2A1	AP2S1	
ACYL CHAIN REMODELLING OF PI%REACTOME%R-HSA-1482922.2	Acyl chain remodelling of PI	PLA2G2A	PLA2G4D	PLA2G4C	PLA2G4A	PLA2G16	PLA2G10	PLA2G1B	PLBD1	PLA2R1	PLA2G2F	PLA2G5	PLA2G2D	PLA2G2E	PLA2G12A	PLA2G4F	MBOAT7	
GENE SILENCING BY RNA%REACTOME%R-HSA-211000.2	Gene Silencing by RNA	BCDIN3D	XPO5	HIST2H2AC	DROSHA	H2AFJ	DGCR8	NUP62	NDC1	SEC13	TNRC6C	NUP133	AGO3	H2AFZ	AGO4	H2AFX	H2AFV	AGO1	HIST2H2BE	AGO2	HIST4H4	NUP50	NUP54	TNRC6A	TNRC6B	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	HIST2H4A	HIST2H4B	NUP43	RAE1	RANBP2	NUP35	NUPL2	NUP37	PIWIL2	TDRKH	PIWIL1	PIWIL4	DDX4	HENMT1	POLR2A	POLR2B	POLR2C	ASZ1	POLR2D	MAEL	POLR2E	POLR2F	MOV10L1	POLR2G	POLR2H	POLR2I	POLR2J	MYBL1	POLR2K	POLR2L	TDRD9	TDRD6	TDRD1	TDRD12	FKBP6	RAN	NUP107	NUP188	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	NUP214	NUP210	HIST1H2AJ	NUP93	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	NUP205	POM121	H2AFB1	TSNAX	HIST1H3J	PRKRA	DICER1	PLD6	AAAS	TARBP2	NUP160	TSN	HIST1H3A	NUP85	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	IPO8	NUP155	H3F3B	HIST1H4K	HIST1H4L	H3F3A	NUP153	H2BFS	HSP90AA1	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
DEFECTIVE OPLAH CAUSES 5-OXOPROLINASE DEFICIENCY (OPLAHD)%REACTOME DATABASE ID RELEASE 74%5578998	Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)	OPLAH	
DOWNSTREAM SIGNALING OF ACTIVATED FGFR4%REACTOME DATABASE ID RELEASE 74%5654716	Downstream signaling of activated FGFR4	PTPN11	KLB	FRS2	FGF20	FRS3	FGF1	FGF23	FGF2	GAB1	FGF4	FGF16	FGF6	NRAS	FGF9	PLCG1	SOS1	FGF19	HRAS	FGF18	PIK3R1	FGFR4	PIK3CA	
ENZYMATIC DEGRADATION OF DOPAMINE BY MONOAMINE OXIDASE%REACTOME DATABASE ID RELEASE 74%379398	Enzymatic degradation of Dopamine by monoamine oxidase	MAOA	COMT	
TRNA MODIFICATION IN THE MITOCHONDRION%REACTOME DATABASE ID RELEASE 74%6787450	tRNA modification in the mitochondrion	MTO1	TRMT10C	GTPBP3	TRIT1	TRMU	KIAA0391	HSD17B10	TRMT61B	
RUNX3 REGULATES WNT SIGNALING%REACTOME DATABASE ID RELEASE 74%8951430	RUNX3 regulates WNT signaling	MYC	CTNNB1	RUNX3	CCND1	LEF1	TCF7L2	TCF7	TCF7L1	
INTERLEUKIN-17 SIGNALING%REACTOME DATABASE ID RELEASE 74%448424	Interleukin-17 signaling	RPS6KA1	RIPK2	MAPK3	FOS	CREB1	DUSP4	TRAF6	UBA52	UBE2V1	DUSP6	DUSP7	CUL1	UBE2N	UBB	TAB3	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	NFKB1	IL25	PPP2CA	MAPK10	TNIP2	PPP2CB	MAPK1	IL17RE	MAPK14	IL17RC	MAPK11	IL17RB	IL17RA	IL17F	IL17C	PPP2R1B	IL17A	MAP2K1	ATF1	ATF2	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	BTRC	IRAK1	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	FBXW11	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	CHUK	RPS6KA2	DUSP3	
BIOSYNTHESIS OF MARESIN CONJUGATES IN TISSUE REGENERATION (MCTR)%REACTOME DATABASE ID RELEASE 74%9026762	Biosynthesis of maresin conjugates in tissue regeneration (MCTR)	LTC4S	GSTM4	
PLASMA LIPOPROTEIN REMODELING%REACTOME%R-HSA-8963899.1	Plasma lipoprotein remodeling	APOF	APOE	APOB	FGF21	GPIHBP1	MBTPS1	ABCG1	APOC3	APOC2	ALB	MBTPS2	PCSK6	PCSK5	LIPC	CREB3L3	LIPG	APOA2	APOA1	APOA4	APOA5	ANGPTL3	ANGPTL4	LPA	CETP	C19orf80	LPL	FURIN	LCAT	LMF2	LMF1	
NR1D1 (REV-ERBA) REPRESSES GENE EXPRESSION%REACTOME%R-HSA-1368071.3	NR1D1 (REV-ERBA) represses gene expression	HDAC3	NR1D1	NCOR1	
BETA-CATENIN INDEPENDENT WNT SIGNALING%REACTOME DATABASE ID RELEASE 74%3858494	Beta-catenin independent WNT signaling	FZD2	FZD5	PDE6G	FZD4	FZD6	NFATC1	GNG12	GNG11	GNG13	GNAO1	TNRC6C	MOV10	UBA52	AGO3	AGO4	GNB2	AGO1	PRKCG	GNB1	AGO2	GNB4	GNB3	CTNNB1	GNB5	TNRC6A	TNRC6B	UBB	UBC	RPS27A	RAC1	WNT5B	ROR1	ROR2	RHOA	CLTB	SCRIB	SMURF2	SMURF1	PRICKLE1	VANGL2	ARRB2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	WNT1	PSMD1	MAP3K7	WNT4	FZD1	PSMA5	PSMA6	PSMA3	FZD7	PSMA4	PSMA1	DAAM1	PSMA2	PSME3	PSME4	PSME1	FZD8	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	AP2A1	PSMB1	PSMF1	SHFM1	PSMB8	AP2A2	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	AP2M1	PSMC1	PSMC2	CLTC	CLTA	PARD6A	AP2S1	PRKCB	PRKCA	AP2B1	DVL1	DVL2	DVL3	RAC2	GNGT1	PPP3CA	PPP3CB	PFN1	GNGT2	GNAT2	PRKG2	PRKG1	WNT5A	RAC3	PLCB3	PLCB1	PLCB2	CAMK2A	LEF1	TCF7	ITPR1	ITPR2	ITPR3	NLK	GNG3	GNG10	PPP3R1	GNG2	WNT11	GNG5	GNG4	GNG7	GNG8	PDE6B	PDE6A	TCF7L2	FZD3	TCF7L1	
POST NMDA RECEPTOR ACTIVATION EVENTS%REACTOME%R-HSA-438064.3	Post NMDA receptor activation events	RPS6KA1	ADCY1	MAPK3	ADCY8	NEFL	CREB1	CAMK2G	NRGN	GRIA1	GRIA2	NRAS	HRAS	CAMKK1	CAMKK2	GRIN2A	LRRC7	PRKAR2B	GRIN2C	KPNA2	CAMK4	CAMK1	GRIN1	MAPK1	PRKX	RAC1	GIT1	SRC	PRKAA1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	PDPK1	DLG2	PRKAB2	PRKAB1	PRKACG	PRKACB	RASGRF2	RASGRF1	PRKAR1B	DLG1	PRKAR1A	DLG3	ACTN2	DLG4	PRKACA	CAMK2A	PRKAR2A	NRG1	GRIN2B	GRIN2D	RPS6KA3	CAMK2B	RPS6KA6	CAMK2D	RPS6KA2	
REGULATION OF PTEN LOCALIZATION%REACTOME DATABASE ID RELEASE 74%8948747	Regulation of PTEN localization	RPS27A	USP7	PML	NEDD4	UBB	XIAP	PTEN	UBC	UBA52	
RAS GTPASE CYCLE MUTANTS%REACTOME DATABASE ID RELEASE 74%9649913	RAS GTPase cycle mutants	NRAS	HRAS	KRAS	
RELEASE%REACTOME DATABASE ID RELEASE 74%168298	Release	
TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES%REACTOME DATABASE ID RELEASE 74%6803207	TP53 Regulates Transcription of Caspase Activators and Caspases	CRADD	ATM	APAF1	NLRC4	TP73	CASP10	TP63	PIDD1	CASP1	CASP6	CASP2	TP53	
SUMO IS PROTEOLYTICALLY PROCESSED%REACTOME DATABASE ID RELEASE 74%3065679	SUMO is proteolytically processed	SUMO1	SUMO3	SUMO2	SENP5	SENP2	SENP1	
MITOTIC G1 PHASE AND G1 S TRANSITION%REACTOME DATABASE ID RELEASE 74%453279	Mitotic G1 phase and G1 S transition	MCM7	MCM8	TYMS	SKP2	ABL1	CDC7	UBA52	CCNA2	CCNA1	CCNE2	CCNE1	MCM3	MCM4	CUL1	MCM5	CCNB1	MCM6	UBB	MCM2	UBC	CDKN2D	CDKN2B	ORC5	CDKN2C	ORC4	RPS27A	ORC6	PPP2CA	ORC1	MYC	ORC3	PPP2CB	ORC2	CDT1	CDC6	RPA1	RPA2	CDK2	TK1	PTK6	CDK1	RPA3	JAK2	HDAC1	PRIM2	PRIM1	POLA1	CABLES1	POLA2	WEE1	PPP2R2A	FBXO5	GMNN	MCM10	DBF4	RPA4	CCND2	CDK6	CDKN2A	PCNA	POLE4	PSMD8	POLE2	PSMD9	CDC45	PSMD6	POLE3	PSMD7	PSMD4	POLE	PSMD5	PSMD2	PSMD3	PSMD1	E2F1	PSMA5	PSMA6	PSMA3	CDKN1A	PSMA4	CDKN1B	PSMA1	PSMA2	PSME3	PSME1	CDC25A	PSME2	PSMD10	PSMD12	PSMD11	PSMD14	TOP2A	PSMD13	LIN54	RBL2	LIN37	MAX	RBL1	PSMB10	LIN9	MYBL2	PSMA7	E2F4	E2F5	LYN	LIN52	DYRK1A	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	E2F2	PSMF1	SHFM1	E2F6	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	RB1	TFDP1	TFDP2	PPP2R1B	E2F3	CKS1B	PPP2R3B	CCND3	CDKN1C	CCNH	DHFR	AKT2	AKT3	RBBP4	AKT1	PPP2R1A	CCND1	CDK4	RRM2	SKP1	CDK7	MNAT1	
P53-INDEPENDENT DNA DAMAGE RESPONSE%REACTOME%R-HSA-69610.4	p53-Independent DNA Damage Response	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	CHEK2	PSME3	CHEK1	PSME4	PSME1	CDC25A	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	UBB	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	
METABOLISM OF VITAMIN K%REACTOME DATABASE ID RELEASE 74%6806664	Metabolism of vitamin K	UBIAD1	VKORC1L1	VKORC1	
PTK6 REGULATES RHO GTPASES, RAS GTPASE AND MAP KINASES%REACTOME%R-HSA-8849471.2	PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	PXN	RHOA	RAC1	PTK6	ARHGAP35	NRAS	DOCK1	HRAS	RASA1	ELMO1	CRK	ELMO2	BCAR1	
EVASION OF OXIDATIVE STRESS INDUCED SENESCENCE DUE TO P14ARF DEFECTS%REACTOME%R-HSA-9646304.2	Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects	CDKN2A	
TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX%REACTOME%R-HSA-9679504.2	Translation of Replicase and Assembly of the Replication Transcription Complex	MAP1LC3B	CHMP2B	CHMP2A	CHMP4C	CHMP4B	CHMP3	CHMP4A	CHMP6	CHMP7	PIK3R4	UVRAG	PIK3C3	BECN1	
FORMATION OF THE HIV-1 EARLY ELONGATION COMPLEX%REACTOME%R-HSA-167158.2	Formation of the HIV-1 Early Elongation Complex	NELFB	CTDP1	CCNH	SUPT4H1	POLR2A	POLR2B	POLR2C	NELFA	POLR2D	NELFCD	NCBP1	NCBP2	POLR2E	POLR2F	NELFE	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	SUPT5H	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	CDK7	ERCC3	ERCC2	MNAT1	
CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR-MEDIATED ACTIVATION OF RAS SIGNALING%REACTOME%R-HSA-442742.2	CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	RPS6KA1	MAPK3	NEFL	CAMK2G	CREB1	NRAS	PDPK1	DLG2	HRAS	LRRC7	RASGRF2	RASGRF1	GRIN1	MAPK1	DLG1	DLG3	ACTN2	DLG4	CAMK2A	GRIN2B	GRIN2D	CAMK2B	RPS6KA3	CAMK2D	RPS6KA6	RPS6KA2	
DEFECTIVE GALT CAN CAUSE GALACTOSEMIA%REACTOME DATABASE ID RELEASE 74%5609978	Defective GALT can cause Galactosemia	GALT	
SIGNALING BY FGFR2%REACTOME DATABASE ID RELEASE 74%5654738	Signaling by FGFR2	MAPK3	PTPN11	HNRNPA1	UBA52	GAB1	CBL	NRAS	PLCG1	SOS1	HRAS	UBB	UBC	RPS27A	PPP2CA	GTF2F1	GTF2F2	PPP2CB	MAPK1	FGFBP1	FGFBP2	FGFBP3	FGF1	RBFOX2	FGF2	FGF3	FGF4	TIA1	HNRNPM	FGF6	FGF7	HNRNPF	ESRP2	FGF9	TIAL1	HNRNPH1	FGF20	FGF23	FGF22	ESRP1	FGF16	MKNK1	FGF18	SPRY2	PIK3R1	PIK3CA	POLR2A	POLR2B	POLR2C	FGF10	NCBP1	POLR2D	NCBP2	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	PPP2R1A	POLR2J	POLR2K	POLR2L	FRS2	FRS3	PTBP1	BRAF	
DAP12 SIGNALING%REACTOME%R-HSA-2424491.2	DAP12 signaling	KLRD1	NRAS	PLCG1	SOS1	HRAS	PIK3R2	PIK3R1	TREM2	SYK	PIK3CA	TYROBP	LCK	GRAP2	LCP2	FYN	RAC1	B2M	PIK3CB	PLCG2	KLRK1	HLA-E	VAV3	VAV2	KLRC2	BTK	
CALCITONIN-LIKE LIGAND RECEPTORS%REACTOME DATABASE ID RELEASE 74%419812	Calcitonin-like ligand receptors	ADM	IAPP	CALCA	CALCR	RAMP2	ADM2	RAMP3	CALCRL	RAMP1	CALCB	
EARLY PHASE OF HIV LIFE CYCLE%REACTOME%R-HSA-162594.2	Early Phase of HIV Life Cycle	KPNA1	CD4	FEN1	PPIA	XRCC4	LIG1	CCR5	LIG4	XRCC6	XRCC5	BANF1	HMGA1	PSIP1	CXCR4	
COHESIN LOADING ONTO CHROMATIN%REACTOME%R-HSA-2470946.1	Cohesin Loading onto Chromatin	MAU2	STAG1	STAG2	SMC3	WAPAL	PDS5B	PDS5A	SMC1A	NIPBL	RAD21	
PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING%REACTOME DATABASE ID RELEASE 74%112308	Presynaptic depolarization and calcium channel opening	CACNB2	CACNA1B	CACNB3	CACNA1A	CACNB4	CACNA1E	CACNG2	CACNG4	CACNA2D3	CACNA2D2	CACNB1	
TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 (RBL1) AND P130 (RBL2) IN COMPLEX WITH HDAC1%REACTOME%R-HSA-1362300.2	Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	CCNA2	LIN54	CDK1	LIN37	RBL2	RBL1	LIN9	MYBL2	E2F4	E2F5	TFDP1	LIN52	HDAC1	TFDP2	E2F1	RBBP4	
CHAPERONE MEDIATED AUTOPHAGY%REACTOME%R-HSA-9613829.3	Chaperone Mediated Autophagy	RPS27A	PCNT	IFT88	ARL13B	HBB	HDAC6	EEF1A1	HSP90AB1	CFTR	HSPA8	UBA52	PLIN3	PLIN2	GFAP	HSP90AA1	LAMP2	CETN1	PARK7	UBB	UBC	RNASE1	
WNT5:FZD7-MEDIATED LEISHMANIA DAMPING%REACTOME DATABASE ID RELEASE 74%9673324	WNT5:FZD7-mediated leishmania damping	JUN	FZD7	DVL1	DVL2	DVL3	WNT5A	NOXA1	NOX1	CYBA	RAC1	NOXO1	MAPK8	
ANTIGEN PROCESSING-CROSS PRESENTATION%REACTOME DATABASE ID RELEASE 74%1236975	Antigen processing-Cross presentation	ITGB5	TIRAP	TAP2	TLR1	TAP1	UBA52	TLR6	TLR2	UBB	UBC	RPS27A	HLA-B	HLA-C	HLA-F	HLA-G	HLA-E	SEC22B	VAMP3	FCGR1B	ITGAV	PSMD8	IKBKB	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	IKBKG	CHUK	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	CTSV	PSMB10	CTSS	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	CTSL	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	LNPEP	PSMB9	PDIA3	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	CD207	PSMC2	CALR	HLA-A	B2M	FCGR1A	VAMP8	BTK	LY96	STX4	SEC61A2	SEC61A1	CD14	CYBA	TLR4	NCF1	NCF2	TAPBP	NCF4	CYBB	SEC61G	SEC61B	MRC2	MRC1	MYD88	SNAP23	CD36	
TRANSLOCATION OF ZAP-70 TO IMMUNOLOGICAL SYNAPSE%REACTOME%R-HSA-202430.5	Translocation of ZAP-70 to Immunological synapse	HLA-DQA1	TRAV19	HLA-DRB5	HLA-DRB4	CD4	HLA-DPB1	HLA-DRA	HLA-DRB3	HLA-DRB1	CD3G	ZAP70	CD3E	CD3D	HLA-DPA1	HLA-DQB2	HLA-DQB1	LCK	PTPN22	HLA-DQA2	
NETRIN-1 SIGNALING%REACTOME%R-HSA-373752.2	Netrin-1 signaling	UNC5A	UNC5B	UNC5C	ROBO1	UNC5D	PTPN11	MAPK12	AGAP2	SLIT1	PRKCQ	SLIT3	SLIT2	HFE2	PLCG1	MAPK13	MAPK8	TRIO	TRPC7	TRPC5	TRPC6	TRPC3	TRPC4	TRPC1	RAC1	MAPK14	MAPK11	WASL	DOCK1	DSCAML1	NCK1	DSCAM	CDC42	RGMB	RGMA	ABLIM1	ABLIM2	ABLIM3	SRC	MYO10	PITPNA	DCC	EZR	NEO1	SIAH2	SIAH1	NTN4	PTK2	NTN1	PAK1	
CLEC7A INFLAMMASOME PATHWAY%REACTOME DATABASE ID RELEASE 74%5660668	CLEC7A inflammasome pathway	NFKB1	MALT1	RELA	CASP8	IL1B	PYCARD	
DEFECTIVE MTRR CAUSES METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE CBLE%REACTOME DATABASE ID RELEASE 74%3359467	Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE	MTRR	MTR	
TRAFFICKING OF AMPA RECEPTORS%REACTOME%R-HSA-399719.1	Trafficking of AMPA receptors	CACNG8	PRKCB	CAMK2G	CACNG2	PRKCA	CACNG3	CACNG4	GRIP1	MDM2	PRKCG	GRIA1	GRIA2	GRIA3	AP2A1	GRIA4	MYO6	AKAP5	DLG1	DLG4	CAMK2A	EPB41L1	TSPAN7	NSF	CAMK2B	PICK1	CAMK2D	
BINDING OF TCF LEF:CTNNB1 TO TARGET GENE PROMOTERS%REACTOME DATABASE ID RELEASE 74%4411364	Binding of TCF LEF:CTNNB1 to target gene promoters	MYC	CTNNB1	AXIN2	RUNX3	LEF1	TCF7L2	TCF7	TCF7L1	
EPIGENETIC REGULATION OF GENE EXPRESSION%REACTOME DATABASE ID RELEASE 74%212165	Epigenetic regulation of gene expression	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	SAP130	H2AFV	SAP30BP	DNMT1	HIST2H2BE	BAZ2A	SMARCA5	HIST4H4	DNMT3B	DDX21	EZH2	HIST1H2BN	HIST1H2BM	HIST1H2BO	HIST1H2BJ	HIST1H2BI	HIST1H2BL	HIST1H2BK	SUZ12	HIST2H4A	HIST2H4B	SIN3A	HDAC2	HDAC1	SF3B1	CBX3	MBD2	POLR2E	POLR2F	POLR2H	POLR2K	POLR2L	DEK	SIN3B	DNMT3A	BAZ1B	TBP	POLR1C	ACTB	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	SIRT1	HIST1H2AB	HIST1H2AJ	ARID4B	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	SAP30	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	SAP30L	CCNH	SAP18	EHMT2	H2AFB1	SUDS3	CHD4	HIST1H3J	CHD3	TTF1	TAF1D	ZNRD1	HIST1H3A	MTA1	RBBP4	MYBBP1A	UHRF1	TAF1B	HIST1H3F	SUV39H1	TAF1C	HIST1H3G	PHF19	TWISTNB	RRP8	TAF1A	HIST1H3H	PHF1	UBTF	HIST1H3I	JARID2	RBBP7	HIST1H3B	TET2	TDG	MTA2	HIST1H3C	TET1	MTA3	HIST1H3D	AEBP2	MBD3	CD3EAP	HIST1H3E	TET3	MTF2	GTF2H1	GSK3B	GTF2H2	H3F3B	DNMT3L	GTF2H3	HIST1H4K	GTF2H4	HIST1H4L	GATAD2B	GTF2H5	GATAD2A	KAT2B	H3F3A	CDK7	KAT2A	H2BFS	ERCC3	HIST1H4A	POLR1A	HIST1H4B	POLR1B	HIST1H4H	ERCC2	HIST1H4I	POLR1E	HIST1H4J	ERCC6	EP300	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	EED	HIST2H2AA3	HIST2H2AA4	
DEFECTIVE SLC6A2 CAUSES ORTHOSTATIC INTOLERANCE (OI)%REACTOME DATABASE ID RELEASE 74%5619109	Defective SLC6A2 causes orthostatic intolerance (OI)	SLC6A2	
TRIF-MEDIATED PROGRAMMED CELL DEATH%REACTOME DATABASE ID RELEASE 74%2562578	TRIF-mediated programmed cell death	RIPK3	LY96	TICAM1	CASP8	RIPK1	CD14	FADD	TLR4	TICAM2	
C6 DEAMINATION OF ADENOSINE%REACTOME DATABASE ID RELEASE 74%75102	C6 deamination of adenosine	ADAR	ADARB1	
DEFECTIVE SRD5A3 CAUSES SRD5A3-CDG (CDG-1Q) AND KHRZ%REACTOME%R-HSA-4755579.1	Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ	SRD5A3	
PHASE 4 - RESTING MEMBRANE POTENTIAL%REACTOME DATABASE ID RELEASE 74%5576886	Phase 4 - resting membrane potential	KCNK5	KCNJ12	KCNJ14	KCNK1	KCNK6	KCNK2	KCNK7	KCNK3	KCNK9	KCNK4	KCNK10	KCNK12	KCNK13	KCNK15	KCNK16	KCNJ2	KCNK17	KCNJ4	KCNK18	
LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX%REACTOME DATABASE ID RELEASE 74%9022537	Loss of MECP2 binding ability to the NCoR SMRT complex	TBL1X	TBL1XR1	HDAC3	NCOR2	NCOR1	GPS2	
INFLAMMASOMES%REACTOME DATABASE ID RELEASE 74%622312	Inflammasomes	NFKB1	TXNIP	P2RX7	BCL2	TXN	MEFV	SUGT1	PYCARD	HSP90AB1	NLRP1	PANX1	AIM2	NFKB2	RELA	NLRP3	NLRC4	APP	PSTPIP1	CASP1	BCL2L1	
G ALPHA (I) SIGNALLING EVENTS%REACTOME%R-HSA-418594.6	G alpha (i) signalling events	RRH	LRP1	LRP2	GPR37L1	ABCA4	PRKAR2B	CXCR4	PPY	PDYN	APOA1	SLC24A1	CCR10	NMS	NMU	CX3CL1	CXCL8	NPB	CXCR5	CXCR6	CXCR1	NPW	CXCR3	CXCR2	CCL4L2	PMCH	NPY2R	NPY1R	APLNR	SUCNR1	OPN3	NMT1	NMT2	OPN5	PYY	NMUR2	PRKCD	NMUR1	TAS2R7	GPSM1	CXCL6	GPSM2	TAS2R9	CXCL9	TAS2R8	PSAP	CXCL3	CXCL5	CCR5	BDKRB2	BDKRB1	TAS2R1	PPBP	TAS2R3	TAS2R5	GPSM3	TAS2R4	NPY5R	PLB1	CORT	RGS18	RGS17	C5AR1	RGS19	C5	RGS14	SRC	NPY4R	RGS13	P2RY12	RGS16	OPRL1	RGS21	RGS20	S1PR3	S1PR2	RGS22	S1PR5	S1PR4	PRKACG	PRKACB	RGS10	RGS12	ADCY9	PRKAR1B	PRKAR1A	PRKAR2A	GNAS	ADCY4	ADCY3	ADCY2	ADCY1	ADCY8	ADCY7	ADCY6	CREB1	ADCY5	PLA2G4A	AWAT2	CAMKK1	CAMKK2	NBEA	CAMK4	SDC4	SDC3	GPC3	SDC1	GPC2	GPC5	FNTA	GPC4	GPC6	FNTB	GUCA1B	PTGDR2	GUCA1A	GABBR2	GUCA1C	PTGER3	CNGA1	GABBR1	CAMKMT	RBP2	RGS9BP	SAG	PPEF1	GUCY2D	RETSAT	GUCY2F	LRP8	GRK1	APOM	GRK7	BCO2	BCO1	RCVRN	AKR1C1	AKR1C4	AKR1B10	PPP1CA	LRP10	METAP1	LRP12	METAP2	HEBP1	ANXA1	FPR1	FPR3	FPR2	PPP2R5D	CCL19	AKR1C3	AGT	CCL20	CAMK2B	CAMK2D	CAMK2G	CXCL10	CCL5	CCL4	GNAL	OPN1SW	OPN1MW	OPN1LW	RBP3	OPN1MW2	CCR1	DHRS3	RLBP1	KPNA2	CCR2	AHCYL1	PRKX	OPRD1	PPP2R1B	CXCL1	CXCL2	PRKCA	C3	GPR17	P2RY13	P2RY14	APP	P2RY4	ADORA3	ADORA1	RGS9	RGS6	RGS7	PPP2CA	SSTR3	PPP2CB	SAA1	MCHR1	MAPK1	RGS11	AGRN	CXCL12	RHO	CNGB1	AGTR2	NPBWR1	NPBWR2	PRKCQ	GPR18	GPR37	SDC2	GPR31	SST	GPR55	CXCL13	CXCL16	GPC1	CXCL11	GNGT1	PPP3CA	PPP3CB	GNGT2	GNAT2	CCL1	PLCB3	PLCB1	APLN	PLCB2	CAMK2A	ITPR1	ITPR2	ITPR3	TAS2R20	RGSL1	GNG3	OXER1	GNG10	PPP3R1	GNG2	TAS2R10	TAS2R13	GNG5	TAS2R14	GNG4	TAS2R16	GNG7	TAS2R19	GNG8	PDE6B	PDE6A	TAS2R40	TAS2R41	TAS2R42	PDE6G	TAS2R43	LPAR1	TAS2R46	LPAR2	GNG12	LPAR3	GNG11	GNG13	PENK	GNAO1	TAS2R30	TAS2R31	GNB2	GNAT1	TAS2R38	PRKCG	TAS2R39	GNB1	PLCB4	PDE1C	LPAR5	GNB4	PDE1B	GNB3	CDK5	PDE1A	ADRBK1	GNB5	TAS2R60	CCR9	CCR8	CCR7	CCR6	CCR4	CCR3	OXGR1	TAS2R50	GAL	SDR9C7	MYO7A	HSD17B6	RPE65	RBP4	RGS4	TTR	RGS5	RDH12	DHRS9	RGS3	RDH11	RGS1	CYP4V2	RDH10	RGS8	HSD17B1	CASR	RBP1	NAPEPLD	RDH16	PCP2	RDH5	LRAT	STRA6	MCHR2	HCAR2	HCAR3	HCAR1	PPP3CC	GRM3	GRM2	GRM4	GRM7	GRM6	GPER1	GRM8	SSTR1	HSPG2	SSTR2	SSTR4	SSTR5	CNR2	CNR1	TAS1R2	TAS1R1	TAS1R3	CHRM2	ACKR3	CHRM4	RXFP4	RXFP3	GNAT3	C3AR1	HRH4	DRD3	DRD4	HTR1E	APOA2	GALR3	GALR2	HTR1F	APOA4	GALR1	HTR1D	NPY	GPR183	HTR1B	PNOC	ADRA2C	HTR5A	ADRA2A	LPL	RGR	GNAI3	CCL13	GNAI1	GNAI2	APOE	CCL16	APOB	LDLR	CCL25	CCL21	GPIHBP1	OPRM1	APOC3	CCL28	CCL27	APOC2	GNAZ	OPRK1	MTNR1A	MTNR1B	RLN3	KNG1	PDE4B	PDE4A	PDE4D	PDE4C	POMC	PPP1R1B	PPP2R1A	PRKACA	INSL5	CX3CR1	CLPS	PNLIP	PF4	
N-GLYCAN ANTENNAE ELONGATION%REACTOME DATABASE ID RELEASE 74%975577	N-Glycan antennae elongation	B4GALT6	B4GALT4	B4GALT5	MGAT5	ST3GAL4	ST6GAL1	MGAT4C	MGAT4A	MGAT4B	ST8SIA6	B4GALT2	B4GALT1	B4GALT3	ST8SIA2	ST8SIA3	
TRP CHANNELS%REACTOME DATABASE ID RELEASE 74%3295583	TRP channels	TRPC4AP	MCOLN1	TRPM1	TRPM2	TRPC7	TRPM7	TRPC5	TRPM8	TRPC6	TRPM5	MCOLN3	TRPM6	TRPC3	TRPA1	TRPC4	TRPM3	TRPC1	TRPM4	MCOLN2	TRPV2	TRPV3	TRPV1	TRPV6	TRPV4	TRPV5	
DEUBIQUITINATION%REACTOME DATABASE ID RELEASE 74%5688426	Deubiquitination	IFIH1	RIPK2	RNF135	MAVS	HIST2H2AC	UBE2D1	CFTR	TRAF3	SKP2	VCP	UBA52	CCNA2	CCNA1	HIST2H2BE	CYLD	TNFAIP3	BIRC2	OTUD7B	BIRC3	VDAC3	VDAC2	UBB	HIST1H2BN	VDAC1	HIST1H2BM	NOD1	HIST1H2BO	NOD2	UBC	HIST1H2BJ	HIST1H2BI	BRCA1	ACTL6A	HIST1H2BL	RPS27A	USP11	HIST1H2BK	TNIP2	KDM1B	CDK1	USP9X	USP21	YY1	USP8	SMAD4	CDC20	USP33	DDB2	USP7	FOXO4	PSMD8	ATXN3	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	HIF1A	PSMD1	TAF9B	AXIN1	IKBKG	APC	MAP3K7	PSMA5	TAF10	PSMA6	BABAM1	PSMA3	PSMA4	UIMC1	PSMA1	PSMA2	PSME3	PSME4	PSME1	USP30	PSME2	BRCC3	MAT2B	PTEN	PSMD10	TRAF6	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	BRE	FAM175A	PSMB10	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	TAB1	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	NFKBIA	PSMC5	USP10	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	ACTB	ESR1	OTUD5	TOMM20	TRAF2	RIPK1	SMAD2	SMAD3	TGFB1	TGFBR1	TGFBR2	BECN1	IDE	USP13	RNF146	UFD1L	RCE1	OTUD3	EP300	TP53	STAM	GATA3	NEDD8	HGS	TOMM70A	STAM2	CLSPN	OGT	USP17L2	MYC	HIST2H2AB	RAD23A	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	TNKS2	TRIM25	HIST1H2AI	TNKS	HIST1H2AH	HIST1H2AK	HIST2H2BF	HIST3H2A	IL33	BARD1	PARK2	RHOA	USP15	SMURF2	UCHL5	SMAD7	DDX58	JOSD2	JOSD1	USP18	PTRH2	ARRB1	ARRB2	ATXN3L	MUL1	ATXN7	KEAP1	POLB	SNX3	OTUD7A	STAMBPL1	VCPIP1	FAM175B	MYSM1	OTUB1	OTUB2	RUVBL1	NFRKB	CDC25A	HCFC1	INO80C	MDM2	TNIP1	INO80B	MDM4	TNIP3	INO80E	INO80D	USP17L4	INO80	USP17L5	BAP1	UCHL1	USP17L8	SENP8	ACTR5	ACTR8	RNF128	UCHL3	FOXK2	TADA2B	FOXK1	TFPT	WDR48	MBD5	MBD6	MCRS1	ADRB2	ADRM1	ASXL1	WDR20	ASXL2	USP17L3	USP17L1	RAD23B	TRRAP	USP5	USP3	FKBP8	STAMBP	TADA3	HIST1H2AE	HIST1H2AD	SMAD1	HIST3H2BB	HIST1H2AC	HIST1H2AB	USP34	HIST1H2AJ	AXIN2	USP17L30	YOD1	ZRANB1	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	USP17L27	HIST1H2BB	RHOT1	USP17L26	USP17L29	HIST1H2BA	USP17L28	USP17L21	HIST1H2BD	NLRP3	USP17L20	HIST1H2BC	USP17L22	USP17L25	USP17L24	SUDS3	USP17L15	USP17L18	USP17L17	USP17L19	USP17L10	USP17L12	USP17L11	USP17L13	CCP110	RNF123	USP37	USP47	USP48	USP49	USP42	USP44	KAT2B	USP14	AR	USP16	KAT2A	USP12	USP19	USP24	USP25	USP26	SIAH2	USP4	USP2	USP20	USP22	USP28	HIST2H2AA3	HIST2H2AA4	
TELOMERE EXTENSION BY TELOMERASE%REACTOME DATABASE ID RELEASE 74%171319	Telomere Extension By Telomerase	TINF2	TERF1	TERF2	RUVBL1	NOP10	POT1	TERF2IP	ACD	CDK2	GAR1	WRAP53	CCNA2	CCNA1	RUVBL2	SHQ1	PIF1	TERT	ANKRD28	RTEL1	DKC1	PPP6C	NHP2	PPP6R3	
BUTYRATE RESPONSE FACTOR 1 (BRF1) BINDS AND DESTABILIZES MRNA%REACTOME%R-HSA-450385.2	Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	ZFP36L1	EXOSC7	EXOSC6	AKT1	EXOSC5	EXOSC4	EXOSC9	EXOSC8	EXOSC3	EXOSC2	EXOSC1	DCP1A	YWHAB	DIS3	XRN1	MAPKAPK2	DCP2	
ENZYMATIC DEGRADATION OF DOPAMINE BY COMT%REACTOME%R-HSA-379397.4	Enzymatic degradation of dopamine by COMT	MAOA	COMT	LRTOMT	
DEFECTIVE GGT1 CAUSES GLUTATHIONURIA (GLUTH)%REACTOME DATABASE ID RELEASE 74%9035968	Defective GGT1 causes Glutathionuria (GLUTH)	GGT1	
TRANSLATION%REACTOME DATABASE ID RELEASE 74%72766	Translation	UBA52	EIF2S2	EIF2S1	RPS27A	EIF2S3	SPCS3	SPCS2	SPCS1	APEH	SEC11A	RPL4	SEC11C	EIF4A2	EIF4A1	RPL5	RPL30	RPL3	RPL32	RPL31	RPL34	RPL10L	RPL8	RPL10A	RPL9	RPL6	RPL7	RPS15	RPS14	RPS17	RPS16	RPL18A	RPS19	RPL36AL	RPS18	RPL36	RPL35	RPL38	RPL37	RPS11	RPL39	RPS10	RPS13	RPS12	RPS9	RPL21	RPS7	EIF1AX	RPS8	RPL23	RPS5	RPL22	RPS6	RPSA	RPL24	ETF1	RPL27	RPL26	RPL29	RPL28	RPS4Y2	RPS4Y1	SRPR	EIF4EBP1	EIF2B5	RPL39L	EIF2B4	EIF2B3	RPN2	RPL41	N6AMT1	EIF2B2	RPL3L	RPN1	RPS26	RPS25	RPS28	EIF5	RPS27	RPS29	RPL27A	RPS20	RPS21	RPS24	RPS23	RPLP1	RPLP0	RPS4X	RPL7A	DDOST	SSR1	RPLP2	EIF2B1	EIF5B	RPL13A	RPS3A	RPL37A	RPL10	RPL12	RPL11	RPL36A	PABPC1	RPS27L	RPS15A	RPL14	RPS3	SRPRB	GSPT2	EIF4H	RPL13	RPL15	GSPT1	RPS2	RPL18	RPL17	EIF4E	EIF4B	RPL19	RPL35A	RPL23A	EIF3M	EIF3K	EIF3L	EIF3I	EIF4G1	EIF3J	EIF3G	EIF3H	EIF3E	RPL22L1	EIF3F	FAU	EIF3C	EIF3D	EIF3A	RPL26L1	EIF3B	SRP14	GFM2	MTRF1L	MRRF	SEC61G	SEC61B	MRPS17	MTFMT	MRPS15	MRPS16	MRPS14	MRPS11	MRPS12	MRPL38	MRPL39	MRPS10	MRPL36	MRPL37	MRPL34	MRPL35	MRPL32	MRPL33	MRPL41	MRPL4	MRPL42	MRPL3	MRPL2	MRPL1	MRPL40	MRPL9	CHCHD1	MRPS28	MRPS26	MRPS27	MRPS24	GFM1	MRPS25	MRPS22	TSFM	MRPS23	TUFM	MRPL49	MRPS18B	MRPS2	MRPS18A	MRPL47	MRPL48	MRPS7	MRPL45	MRPS6	MRPL46	MRPL43	MRPS5	MRPS18C	MRPL44	MRPL52	OXA1L	MRPL53	MRPL50	MRPS9	MRPL51	AURKAIP1	DAP3	MRPS35	MRPS36	MRPL18	MRPS33	MRPS34	MRPL19	MRPL16	MRPS31	MRPL17	MTIF2	MRPL14	MRPS30	MTIF3	MRPL15	MRPL12	MRPL13	MRPL57	MRPL10	MRPL54	MRPL11	MRPL55	MRPL20	ICT1	GADD45GIP1	PTCD3	MRPL27	MRPL28	ERAL1	MRPL23	MRPL24	MRPL21	MRPL22	MRPL30	RARS2	AARS2	MARS2	PARS2	DARS2	YARS2	HARS2	WARS2	FARS2	LARS2	SARS2	NARS2	IARS2	TARS2	VARS2	CARS2	EARS2	EEF1B2	EEF1A1	EEF1G	EEF1D	EEF1A2	EEF2	YARS	CARS	DARS	WARS	VARS	TARS	SARS	EPRS	SEC61A2	NARS	SEC61A1	AIMP1	AIMP2	QARS	KARS	PPA1	LARS	PPA2	MARS	RARS	GARS	HARS	IARS	EEF1E1	FARSA	FARSB	AARS	TRMT112	SRP19	TRAM1	SRP54	SSR4	SSR2	SSR3	SRP9	SRP72	SRP68	
POLYMERASE SWITCHING%REACTOME%R-HSA-69091.2	Polymerase switching	POLA2	RFC5	RFC3	PCNA	RFC4	RFC1	RFC2	POLD3	POLD4	POLD1	POLD2	PRIM2	PRIM1	POLA1	
METABOLISM OF FOLATE AND PTERINES%REACTOME DATABASE ID RELEASE 74%196757	Metabolism of folate and pterines	FOLR2	MTHFD1	MTHFD2	DHFRL1	MTHFD2L	SHMT2	SLC46A1	SLC19A1	SHMT1	MTHFR	MTHFS	MTHFD1L	ALDH1L1	DHFR	ALDH1L2	SLC25A32	
RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION%REACTOME%R-HSA-8931987.1	RUNX1 regulates estrogen receptor mediated transcription	CBFB	GPAM	ESR1	KCTD6	AXIN1	RUNX1	
DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE%REACTOME DATABASE ID RELEASE 74%4641262	Disassembly of the destruction complex and recruitment of AXIN to the membrane	FZD2	FZD5	WNT3A	LRP5	LRP6	CSNK1A1	DVL1	DVL2	CTNNB1	DVL3	CSNK1G2	PPP2CA	PPP2CB	CAV1	PPP2R1A	GSK3B	PPP2R5E	FRAT1	PPP2R5B	FRAT2	PPP2R5A	PPP2R5D	PPP2R5C	WNT8A	WNT8B	PPP2R1B	AMER1	WNT1	AXIN1	APC	FZD1	
COMPETING ENDOGENOUS RNAS (CERNAS) REGULATE PTEN TRANSLATION%REACTOME%R-HSA-8948700.1	Competing endogenous RNAs (ceRNAs) regulate PTEN translation	AGO2	TNRC6A	TNRC6B	TNRC6C	MOV10	AGO3	AGO4	AGO1	
HEMOSTASIS%REACTOME%R-HSA-109582.2	Hemostasis	TUBA4A	PRKAR2B	SPARC	MPL	THPO	SLC7A11	SLC7A10	SLC7A5	SLC7A6	STXBP3	ABCC4	SLC7A7	SLC7A8	APOA1	PIK3CB	PIK3CG	VAV1	PIK3R5	PDE2A	RAB27B	PLCG2	SLC3A2	JAK2	JCHAIN	PLAUR	SLC8A3	HSPA5	CD109	CEACAM5	BRPF3	FAM49B	F11R	ISLR	LAMP2	HABP4	FAM3C	CHID1	PRKCD	APLP2	ACTN1	YWHAZ	SERPINF2	ACTN4	GTPBP2	SYTL4	SEPP1	TMX3	TAGLN2	SCG3	NHLRC2	TEX264	STXBP2	ENDOD1	A1BG	CYB5R1	APOH	PSAP	VTI1B	TGFB2	TGFB3	MAPK14	RARRES2	IGF2	IGF1	PPBP	MANF	SELP	SCCPDH	CALU	MAGED2	HRG	FERMT3	VAV3	LGALS3BP	SERPINA3	CLU	ORM1	VAV2	ECM1	WDR1	PLEK	OLA1	CTSW	ORM2	SERPINA4	PLAU	TMSB4X	PHACTR2	TIMP3	SRC	QSOX1	SRGN	AHSG	ANXA5	P2RY12	MMRN1	TOR4A	CD63	ITIH4	ITIH3	TTN	CLEC3B	CDC37L1	SPP2	PDE11A	LY6G6F	TGFB1	PCDH7	LHFPL2	PCYOX1L	GAS6	RAC2	NOS1	NOS2	PLAT	NOS3	PRKACG	PRKACB	PDE10A	PRKAR1B	PRKAR1A	ACTN2	KIF3A	PRKAR2A	TLN1	PDGFB	GNAS	PTK2	PLA2G4A	ITGAX	MGLL	ITGA3	ITGA6	CD47	JAM2	JAM3	APBB1IP	P2RX6	P2RX5	STIM1	P2RX3	P2RX2	P2RX1	ORAI2	ORAI1	ITGA2B	SDC4	SDC3	SDC1	PIK3R6	HGF	TBXA2R	VCL	ALDOA	RAP1B	RAP1A	LRP8	ITGB3	LCP2	ARRB1	ARRB2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	SERPINB2	ANXA2	PPP2R5C	TSPAN7	PICK1	CSK	ANGPT1	PTPN11	PRKCZ	TEK	YES1	FGR	PPP2R1B	PRKCB	PRKCA	CFD	PDE5A	MRVI1	HIST2H3A	PDE9A	HIST2H3D	HIST2H3C	APP	HIST1H3J	HIST1H3A	P2RY1	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	KIF5B	KIF5A	H3F3A	KIF21A	SERPINB6	KIF21B	ITGAM	KIFAP3	ITGB2	CD36	KIF16B	KIF20A	KIF20B	TNFRSF10D	KLC1	L1CAM	KLC4	KLC3	KLC2	KIF3B	RACGAP1	KIF3C	PPP2CA	KIF18A	KIF18B	PPP2CB	KIF4B	KIF4A	MAPK1	CDK2	KIF11	KIF15	KIF19	CAPZB	GNA13	KIF13B	KIF1C	KIF1B	KIF1A	ATP2A3	KIF25	ATP2A2	LEFTY2	ATP2A1	KIF23	KIF22	KIF6	KIF27	CD9	MAG	KIF9	KIFC2	KIF2A	KIFC1	KIF2C	KIF2B	SRI	SERPINB8	S100A10	SLC16A1	ATP2B4	ATP2B3	ATP2B2	ATP2B1	ITGAV	ITGA2	ITGA1	C6orf25	PDPN	CLEC1B	CENPE	KIF26A	CAPZA1	KIF26B	CAPZA2	IGKV2-28	IGKV1-12	IGKV3D-20	VPS45	IGKV2D-28	IGKV4-1	PRKCQ	ITGAL	IGKV2D-30	RASGRP2	RASGRP1	IGKV3-11	LYN	GUCY1B3	IGKV5-2	GUCY1A3	SDC2	GUCY1A2	CD84	SIRPG	VPREB3	VPREB1	SIRPA	SLC16A8	SLC16A3	CXADR	PSG1	PSG3	PSG2	MIF	FCAMR	CAP1	PSG9	PSG8	PSG5	PSG4	PSG6	GYPA	GYPC	APOOL	GYPB	CD99L2	SOD1	PSG11	GLG1	TNFRSF10B	CD99	GP6	TNFRSF10A	SELE	GPC1	SELL	ESAM	TREM1	SPN	OLR1	AMICA1	FCER1G	CEACAM3	CD48	SELPLG	EPCAM	GNA14	CD58	GNA15	CD74	GNA11	PPIL2	GNA12	MERTK	PTPN6	GNAQ	ITGB1	F2RL2	CD2	IGLL1	CEACAM1	F2RL3	PDPK1	CD244	CEACAM6	FN1	SLC7A9	PIK3R3	CEACAM8	ITGA5	PIK3R2	PAFAH2	PIK3R1	PIK3CA	LCK	GNGT1	AKT1	GNGT2	PRKG2	FYN	CAV1	ITPR1	ITPR2	ITPR3	SERPINE1	GNG3	GNG10	KDM1A	JMJD1C	GNG2	DOCK10	DOCK11	GNG5	MYB	GNG4	IFNA13	GNG7	IFNA14	GNG8	IFNA16	IFNA17	HBE1	ZFPM2	TP53	ZFPM1	IFNA10	RAF1	GATA6	AK3	GATA5	GATA4	AAMP	GATA3	GNG12	GATA2	GNG11	GATA1	GNG13	PHF21A	MICAL1	ABL1	IFNA21	NFE2	CBX5	GNB2	HBG2	PRKCG	HBG1	GNB1	EHD1	EHD2	GNB4	EHD3	PDE1B	GNB3	CDK5	PDE1A	MAFG	GNB5	MAFF	MAFK	RAB5A	TF	DOCK6	IFNA5	DOCK5	IFNA4	DOCK4	IFNA7	DOCK3	IFNA6	IFNA1	DOCK9	DOCK8	DOCK7	IFNA2	HBB	HBD	IFNA8	AKAP10	SIN3A	HMG20B	RAC1	ITPK1	RBSN	RAD51B	RAD51C	IRF1	IRF2	DOCK2	DOCK1	HDAC2	HDAC1	LRRC16A	AKAP1	CDC42	MFN1	MFN2	SH2B3	SH2B1	IFNB1	CABLES1	CABLES2	WEE1	FLNA	PPIA	RHOA	RHOB	GRB7	ANGPT4	ANGPT2	DOK2	GRB14	PTPN1	SYK	CRK	RAPGEF3	BCAR1	RAPGEF4	BSG	LAT	CFL1	DGKG	DGKE	DGKD	DAGLA	DGKB	DGKA	ABHD6	ABHD12	PRKCH	MAPK3	PRKCE	DGKZ	DGKQ	DAGLB	DGKK	DGKI	A2M	DGKH	SHC1	EGF	NRAS	PLCG1	SOS1	ITGA10	HRAS	GNAT3	IGHA1	TIMP1	INPP5D	FIGF	TRPC7	VEGFB	TRPC6	VEGFC	MMP1	TRPC3	VEGFA	SERPINA1	ADRA2C	CD44	ADRA2A	PLG	GNAI3	GNAI1	GNAI2	APOB	STX4	ITGA4	KLKB1	ATP1B3	ATP1B2	ATP1B1	THBS1	ALB	SERPINE2	SERPINC1	PROS1	F13A1	PRCP	PTGIR	TFPI	KNG1	SERPINA5	THBD	P2RX7	PFN1	C1QBP	KCNMB1	PF4V1	P2RX4	KCNMB2	CD177	KCNMB3	FGB	PPP2R1A	FGA	KCNMB4	F10	RHOG	SERPIND1	VWF	PRKACA	GP1BB	F12	F11	F2R	FGG	GP1BA	F2	GP5	F3	F5	F7	GP9	PROCR	F8	F9	SLC8A1	KCNMA1	SLC8A2	PROC	SERPING1	PRTN3	F13B	PF4	
CONDENSATION OF PROMETAPHASE CHROMOSOMES%REACTOME%R-HSA-2514853.2	Condensation of Prometaphase Chromosomes	CSNK2A1	SMC4	CCNB2	CSNK2A2	NCAPD2	SMC2	CCNB1	NCAPG	NCAPH	CSNK2B	CDK1	
ONCOGENE INDUCED SENESCENCE%REACTOME%R-HSA-2559585.6	Oncogene Induced Senescence	MAPK3	E2F3	SP1	TNRC6C	MDM2	MOV10	MDM4	AGO3	UBA52	AGO4	AGO1	ERF	TNRC6A	TNRC6B	UBB	UBC	E2F2	CDKN2D	CDKN2B	CDKN2C	RPS27A	CDK6	CDKN2A	MAPK1	CDK4	ETS1	ETS2	RB1	TFDP1	TFDP2	ID1	E2F1	TP53	
N-GLYCAN TRIMMING AND ELONGATION IN THE CIS-GOLGI%REACTOME%R-HSA-964739.1	N-glycan trimming and elongation in the cis-Golgi	MANEA	MAN1C1	MAN1A2	MAN1A1	MGAT1	
RNA POLYMERASE II TRANSCRIPTION PRE-INITIATION AND PROMOTER OPENING%REACTOME%R-HSA-73779.2	RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	TAF11	TAF4B	TAF7	TAF6	TAF5	TAF4	TAF3	TAF2	TAF1	CCNH	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	TBP	GTF2F1	POLR2G	GTF2F2	POLR2H	POLR2I	POLR2J	POLR2K	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	GTF2A1	CDK7	GTF2A2	GTF2B	ERCC3	TAF9	TAF1L	AK6	ERCC2	GTF2E1	GTF2E2	TAF7L	MNAT1	TAF9B	TAF15	TAF12	TAF13	TAF10	
ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS%REACTOME DATABASE ID RELEASE 74%112303	Electric Transmission Across Gap Junctions	GJC1	GJD2	GJA10	PANX1	PANX2	
ERK1 ERK2 PATHWAY%REACTOME%R-HSA-5684996.4	ERK1 ERK2 pathway	UBA52	UBB	UBC	RPS27A	PPP2CA	PPP2CB	MAPK1	IRS2	PIK3CB	CDK1	JAK2	IL6	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	PRKCQ	PSMD14	PSMD13	YWHAB	PSMB10	RASGRP1	PSMA7	RASGRP4	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	IRS1	SRC	IL6R	FN1	PIK3R2	PIK3R1	PIK3CA	RBX1	ARAF	WDR83	PRKG2	FYN	SYNGAP1	DLG1	GOLGA7	DLG3	ACTN2	DLG4	PAQR3	FLT3LG	FRS2	CAMK2A	FRS3	EREG	BTC	TLN1	PDGFB	TGFA	IQGAP1	RCE1	RALGDS	BRAP	ICMT	BRAF	GRIN2B	PTK2	GRIN2D	PPP5C	ARTN	RGL3	RGL1	RGL2	RET	RAF1	AREG	PEA15	NEFL	JAK3	JAK1	DUSP4	DUSP5	LYPLA1	DUSP2	DUSP1	GFRA1	DUSP8	GFRA3	IL17RD	DUSP9	GFRA2	DUSP6	DUSP7	GFRA4	CNKSR2	APBB1IP	CNKSR1	MRAS	LRRC7	KIT	RAPGEF2	HBEGF	SHOC2	DAB2IP	RANBP9	USP17L2	GRIN1	EPGN	ZDHHC9	KBTBD7	KLB	CSF2	ITGA2B	PEBP1	IL5RA	FGF1	FGF2	FGF3	FGF4	PPP1CC	FGF6	FGF7	FNTA	FGF9	FNTB	NRTN	PDGFRB	PDGFRA	MAP2K1	MAP2K2	HGF	VCL	SHC2	SHC3	CUL3	ARL2	CSF2RB	RASAL1	PHB	RASAL2	RASAL3	CSF2RA	RASGRP3	RAP1B	RAP1A	FGF20	MARK3	FGF23	FGF22	PSPN	IL2	FGF16	ERBB2	IL3	IL5	DLG2	GDNF	PTPRA	FGF19	FGF18	NF1	FGFR4	MAP3K11	BCL2L1	FGF10	FLT3	ITGB3	RASGRF2	RASGRF1	ARRB1	LAMTOR2	ARRB2	DUSP16	SPRED3	LAMTOR3	SPRED2	SPRED1	DUSP10	RASGEF1A	PPP2R5E	KSR1	PPP2R5B	PPP2R5A	PPP2R5D	NRG1	PPP2R5C	KSR2	NRG2	RASA3	NRG3	RASA4	NRG4	RASA1	IL3RA	RASA2	MET	CAMK2B	CAMK2D	ABHD17C	IL2RG	PDE6D	MAPK3	CSK	NCAM1	CAMK2G	ANGPT1	PTPN11	MAPK12	ABHD17B	ABHD17A	IL2RA	IL2RB	KRAS	TEK	SHC1	PTPN7	EGF	PTPN3	EGFR	NRAS	SOS1	HRAS	PPP2R1B	SPTAN1	SPTB	SPTBN4	SPTBN5	SPTA1	TYK2	SPTBN1	SPTBN2	PPP1CB	FGB	PPP2R1A	FGA	VWF	FGG	
INTRACELLULAR OXYGEN TRANSPORT%REACTOME DATABASE ID RELEASE 74%8981607	Intracellular oxygen transport	NGB	CYGB	MB	
NILOTINIB-RESISTANT KIT MUTANTS%REACTOME DATABASE ID RELEASE 74%9669926	Nilotinib-resistant KIT mutants	KIT	
COOPERATION OF PDCL (PHLP1) AND TRIC CCT IN G-PROTEIN BETA FOLDING%REACTOME DATABASE ID RELEASE 74%6814122	Cooperation of PDCL (PhLP1) and TRiC CCT in G-protein beta folding	CSNK2A1	CSNK2A2	GNG12	GNG11	GNG13	GNAO1	CCT6B	RGS9	GNB2	GNAZ	GNAT1	RGS6	CSNK2B	RGS7	GNB1	GNB4	GNB3	GNB5	GNAT3	CCT3	CCT2	GNGT1	GNGT2	GNAT2	CCT7	CCT6A	PDCL	TCP1	RGS11	CCT8	CCT5	CCT4	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	GNAI3	GNAI1	GNAI2	
COPI-INDEPENDENT GOLGI-TO-ER RETROGRADE TRAFFIC%REACTOME DATABASE ID RELEASE 74%6811436	COPI-independent Golgi-to-ER retrograde traffic	CAPZA3	DYNLL1	DYNC1LI1	CAPZA1	DYNC1LI2	CAPZA2	PLA2G4A	DYNLL2	RAB18	RAB3GAP2	ACTR10	RAB3GAP1	PAFAH1B1	DYNC1I2	DCTN2	DCTN3	AGPAT3	PAFAH1B3	PAFAH1B2	DCTN6	PLA2G6	RAB6A	DCTN5	RAB6B	DCTN1	DCTN4	ACTR1A	DYNC1H1	BICD1	BICD2	CAPZB	DYNC1I1	GALNT2	GALNT1	
DEFECTIVE MTR CAUSES METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE CBLG%REACTOME DATABASE ID RELEASE 74%3359469	Defective MTR causes methylmalonic aciduria and homocystinuria type cblG	MTRR	MTR	
MYD88-INDEPENDENT TLR4 CASCADE%REACTOME DATABASE ID RELEASE 74%166166	MyD88-independent TLR4 cascade	RPS6KA1	RIPK3	RIPK2	MAPK3	FOS	CREB1	UBE2D2	PTPN11	UBE2D1	TBK1	DUSP4	IRF3	TRAF3	TRAF6	IRF7	UBA52	UBE2V1	DUSP6	BIRC2	DUSP7	CUL1	RELA	BIRC3	UBE2N	UBB	TAB3	TAB2	NOD1	TAB1	MAPKAPK2	NOD2	TANK	UBC	MAPK9	MAPK8	MAPK7	IRAK2	RPS27A	NFKB1	S100B	PPP2CA	NFKBIA	MAPK10	TNIP2	PPP2CB	SAA1	MAPK1	NFKBIB	MAPK14	MAPK11	PPP2R1B	MAP2K1	TICAM2	LY96	TICAM1	CASP8	RIPK1	CD14	FADD	TLR4	ATF1	APP	ATF2	UBE2D3	ELK1	MAP2K3	MEF2A	MAP2K4	MEF2C	MAP3K8	VRK3	PPP2R1A	MAPKAPK3	AGER	BTRC	IRAK1	S100A12	PPP2R5D	MAP2K7	MAP2K6	JUN	SKP1	IKBKB	NFKB2	HMGB1	FBXW11	NKIRAS1	NKIRAS2	IKBKG	RPS6KA3	MAP3K7	RPS6KA5	IKBKE	CHUK	RPS6KA2	DUSP3	
RUNX2 REGULATES GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS%REACTOME%R-HSA-8941333.1	RUNX2 regulates genes involved in differentiation of myeloid cells	CBFB	LGALS3	RUNX1	
INTERLEUKIN-6 FAMILY SIGNALING%REACTOME DATABASE ID RELEASE 74%6783589	Interleukin-6 family signaling	IL6	PTPN11	IL6ST	JAK1	IL11	CNTFR	CNTF	TYK2	OSMR	IL31RA	STAT1	SOCS3	STAT3	CBL	IL31	CTF1	OSM	IL6R	JAK2	LIFR	IL11RA	LIF	CLCF1	CRLF1	
FORMATION OF HIV-1 ELONGATION COMPLEX CONTAINING HIV-1 TAT%REACTOME DATABASE ID RELEASE 74%167200	Formation of HIV-1 elongation complex containing HIV-1 Tat	NELFB	CTDP1	CCNH	ELL	CCNT1	SUPT4H1	POLR2A	TCEB3	POLR2B	TCEB2	POLR2C	TCEB1	NELFA	POLR2D	NELFCD	NCBP1	TCEB3C	NCBP2	POLR2E	TCEB3CL	POLR2F	TCEB3B	NELFE	GTF2F1	POLR2G	SUPT16H	GTF2F2	POLR2H	SSRP1	POLR2I	SUPT5H	POLR2J	CDK9	TCEA1	POLR2K	TCEB3CL2	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	CDK7	ERCC3	ERCC2	MNAT1	
SIGNALING BY NOTCH4%REACTOME%R-HSA-9013694.2	Signaling by NOTCH4	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	NCSTN	PSME3	PSME1	MAML3	PSME2	MAMLD1	PSMD10	UBA52	PSMD12	PSMD11	PSMD14	NOTCH1	PSMD13	PSMB10	HEY1	PSMA7	HEY2	CUL1	PSMB6	PSMB7	PSMB4	UBB	YWHAZ	PSMB5	PSMB2	PSMB3	UBC	PSMB1	PSMF1	SHFM1	PSMB8	RPS27A	PSMB9	FLT4	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	SNW1	ACTA2	NOTCH4	SMAD3	AKT1	RBX1	NOTCH2	MAML2	MAML1	KAT2B	PSMD8	SKP1	PSEN2	RBPJ	ADAM10	KAT2A	PSMD9	PSMD6	DLL4	PSMD7	APH1A	PSMD4	PSMD5	APH1B	PSMD2	CREBBP	PSMD3	EP300	PSMD1	HES1	HES5	PSENEN	PSEN1	PSMA5	JAG1	TACC3	
SUMOYLATION%REACTOME DATABASE ID RELEASE 74%2990846	SUMOylation	PHC2	STAG1	STAG2	PHC1	NUP62	NDC1	SEC13	NUP133	PHC3	RANGAP1	CBX5	SMC1A	PPARGC1A	INCENP	DNMT1	BIRC5	HIST4H4	DNMT3B	NUP50	AURKB	AURKA	NUP54	NRIP1	NOP58	RING1	BRCA1	ZNF350	SUZ12	XPC	HIST2H4A	HIST2H4B	BLM	NUP43	RAE1	RANBP2	RPA1	SIN3A	NUP35	NUPL2	NUP37	SATB1	HNRNPK	PPARG	PPARA	HNRNPC	HDAC2	HDAC1	PARK7	WRN	TFAP2B	RAD52	TFAP2C	MDC1	SP100	RORA	DAXX	PGR	ING2	NCOR2	EID3	RARA	PML	CDKN2A	MBD1	DDX5	PCNA	HIPK2	SP3	PCGF2	FOXL2	NSMCE4A	UHRF2	NSMCE2	NSMCE1	ZBED1	IKBKG	UBA2	HERC2	DNMT3A	RNF168	MKL1	TP53BP1	MDM2	HDAC4	SMC5	SMC6	TOP2A	HDAC7	DDX17	TOP2B	RELA	SUMO3	SUMO2	PIAS4	ZNF131	NPM1	PIAS3	TOP1	NDNL2	NFKBIA	XRCC4	PARP1	MITF	NR3C2	HIC1	TRIM28	NUP107	SUMO1	NUP188	NCOA1	UBE2I	NCOA2	ESR1	CBX8	VHL	CBX4	CBX2	NR5A1	NUP214	L3MBTL2	NR4A2	NUP210	RXRA	THRB	NR3C1	NUP93	NR1H2	TOPORS	BMI1	NR2C1	SATB2	PIAS1	NUP205	POM121	CHD3	AAAS	NUP160	MTA1	NUP85	TPR	CETN2	NUP88	VDR	SAE1	TDG	SENP5	NUP155	HIST1H4K	SAFB	RNF2	HIST1H4L	SENP2	SENP1	TRIM27	AR	NUP153	NFKB2	SMC3	HIST1H4A	HIST1H4B	HIST1H4H	CDCA8	HIST1H4I	RWDD3	CREBBP	HIST1H4J	EP300	HIST1H4C	HIST1H4D	HIST1H4E	CTBP1	HIST1H4F	IKBKE	TP53	RAD21	
DISORDERS OF NERVOUS SYSTEM DEVELOPMENT%REACTOME%R-HSA-9697154.1	Disorders of Nervous System Development	CAMK4	TBL1X	HDAC1	TBL1XR1	SIN3A	HDAC3	PRKACA	NCOR2	NCOR1	GPS2	
ACYL CHAIN REMODELLING OF PG%REACTOME%R-HSA-1482925.1	Acyl chain remodelling of PG	PLA2G2A	PLA2G4D	PLA2G4B	PLA2G4A	LPCAT4	CRLS1	PLA2G10	PLA2G1B	PLA2R1	LPGAT1	LPCAT1	PLA2G3	PLA2G2F	PLA2G5	PLA2G2D	PLA2G2E	PLA2G12A	PLA2G4F	
SIGNALING DOWNSTREAM OF RAS MUTANTS%REACTOME%R-HSA-9649948.1	Signaling downstream of RAS mutants	MAPK3	RAF1	CSK	PHB	CAMK2G	SRC	RAP1B	RAP1A	MARK3	KRAS	YWHAB	NRAS	FN1	CNKSR2	HRAS	APBB1IP	CNKSR1	MAP3K11	ITGB3	ARRB1	ARAF	ARRB2	MAPK1	FGB	FGA	ITGA2B	VWF	CAMK2A	PEBP1	KSR1	FGG	TLN1	KSR2	IQGAP1	JAK2	BRAP	BRAF	MAP2K1	MAP2K2	CAMK2B	VCL	CAMK2D	
FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE%REACTOME DATABASE ID RELEASE 74%2855086	Ficolins bind to repetitive carbohydrate structures on the target cell surface	FCN1	MASP1	FCN2	FCN3	
CHROMATIN MODIFYING ENZYMES%REACTOME DATABASE ID RELEASE 74%3247509	Chromatin modifying enzymes	SETD8	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	EZH2	HIST1H2BN	HIST1H2BM	ACTL6B	HIST1H2BO	PRDM9	HIST1H2BJ	HIST1H2BI	ACTL6A	HIST1H2BL	TBL1X	HIST1H2BK	SUZ12	HIST2H4A	HIST2H4B	KDM3A	KDM1B	KDM4A	KAT8	KAT7	SUPT20H	ATXN7L3	CSRP2BP	PADI3	PADI4	PADI1	PADI6	TADA2A	ZZZ3	JAK2	IKBKAP	ING4	ING3	PAX3	SUPT3H	TAF6L	CCDC101	BRD8	ELP2	MECOM	ELP3	ELP4	ELP5	EHMT1	ELP6	JADE1	JADE3	YEATS4	JADE2	TBL1XR1	SUPT7L	MORF4L1	KAT6B	MORF4L2	HAT1	ENY2	TAF5L	MEAF6	MBIP	DMAP1	DR1	MRGBP	YEATS2	KMT2D	TADA1	KMT2A	VPS72	KMT2C	MSL2	MSL3	MSL1	KANSL1	KDM6A	KANSL2	KANSL3	ING5	PRMT5	BRD1	SUV420H2	KMT2E	SUV39H2	SETD2	SETD3	SETD6	SETD7	SUV420H1	KMT2B	WHSC1L1	ASH1L	DOT1L	NSD1	PRDM16	SMYD3	TAF9	KAT6A	ATF7IP	SETDB1	AK6	SETDB2	SMYD2	TAF12	BRPF1	TAF10	BRPF3	WHSC1	DNMT3A	KDM4B	RUVBL2	RELA	NFKB1	RPS2	SMARCA4	SMARCB1	KDM5B	ACTB	EPC1	NCOA1	EP400	NCOA2	SMARCC1	SMARCC2	KDM6B	SMARCA2	PBRM1	ARID2	GPS2	SUV39H1	PRMT7	COPRS	DPY30	AEBP2	CCND1	CDK4	KDM1A	CREBBP	EP300	EED	SETD1B	SETD1A	PHF21A	SAP130	CARM1	OGT	KDM4C	BRWD1	HIST2H2AB	HIST1H2AG	HIST1H2AA	HIST1H2AM	HIST1H2AL	HIST1H2AI	HIST1H2AH	HMG20B	HIST1H2AK	HIST2H2BF	HIST3H2A	HDAC2	HDAC1	PADI2	ASH2L	KDM7A	NCOR2	NCOR1	CLOCK	ATXN7	WDR77	PHF20	RUVBL1	HCFC1	SMARCD1	PRMT1	SMARCD2	HDAC8	TADA2B	SMARCE1	MCRS1	WDR5	HDAC10	TRRAP	PRMT6	TADA3	KDM5A	PHF2	HIST1H2AE	HIST1H2AD	KDM5C	SMARCD3	KDM5D	HDAC3	HIST3H2BB	PHF8	HIST1H2AC	UTY	HIST1H2AB	KDM2A	KDM2B	ARID5B	JMJD6	KDM3B	ARID4A	HIST1H2AJ	KDM4D	MINA	ARID4B	RBBP5	ARID1A	ARID1B	HIST2H3A	PRMT3	HIST1H2BF	HIST1H2BE	KAT5	HIST1H2BH	SAP30	HIST1H2BG	HIST2H3D	BRMS1	HIST1H2BB	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	SAP30L	SAP18	EHMT2	H2AFB1	SUDS3	CHD4	HIST1H3J	CHD3	ATF2	REST	HIST1H3A	MTA1	RBBP4	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	RBBP7	HIST1H3B	MTA2	HIST1H3C	MTA3	HIST1H3D	MBD3	HIST1H3E	HIST1H4K	HIST1H4L	GATAD2B	GATAD2A	KAT2B	KAT2A	NFKB2	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	USP22	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
S33 MUTANTS OF BETA-CATENIN AREN'T PHOSPHORYLATED%REACTOME%R-HSA-5358747.1	S33 mutants of beta-catenin aren't phosphorylated	PPP2CA	PPP2CB	CSNK1A1	PPP2R1A	GSK3B	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	CTNNB1	PPP2R1B	AMER1	AXIN1	APC	
POST-TRANSCRIPTIONAL SILENCING BY SMALL RNAS%REACTOME%R-HSA-426496.2	Post-transcriptional silencing by small RNAs	AGO2	TNRC6A	TNRC6B	TNRC6C	AGO3	AGO4	AGO1	
G BETA:GAMMA SIGNALLING THROUGH CDC42%REACTOME DATABASE ID RELEASE 74%8964616	G beta:gamma signalling through CDC42	GNGT1	GNGT2	GNG12	GNG11	GNG13	GNB2	ARHGEF6	GNB1	GNG3	GNB4	GNG10	GNB3	GNG2	GNB5	GNG5	GNG4	CDC42	GNG7	GNG8	PAK1	
SYNTHESIS OF 15-EICOSATETRAENOIC ACID DERIVATIVES%REACTOME%R-HSA-2142770.1	Synthesis of 15-eicosatetraenoic acid derivatives	GPX1	GPX4	PTGS2	ALOX15B	ALOX15	GPX2	
REGULATION OF PTEN MRNA TRANSLATION%REACTOME DATABASE ID RELEASE 74%8943723	Regulation of PTEN mRNA translation	AGO2	TNRC6A	TNRC6B	PTEN	TNRC6C	MOV10	AGO3	AGO4	AGO1	
ANTIMICROBIAL PEPTIDES%REACTOME DATABASE ID RELEASE 74%6803157	Antimicrobial peptides	LEAP2	DEFB119	BPIFB2	DEFB118	BPIFB1	DEFB116	BPIFB4	DEFB115	BPIFB6	DEFB114	TLR1	ELANE	DEFB105A	DEFB105B	DEFB113	DEFB112	PI3	DEFB110	BPI	DEFB106B	DEFB106A	TLR2	DEFB129	DEFB128	DEFB127	LCN2	DEFB126	DEFB125	DEFB124	CTSG	DEFB123	DEFB107A	DEFB121	ATOX1	S100A7A	DEFB107B	EPPIN-WFDC6	PLA2G2A	CCR6	ITLN1	CCR2	DEFB136	DEFB135	DEFB134	DEFB133	DEFB108B	DEFB132	DCD	DEFB131	DEFB4A	EPPIN	DEFB4B	LTF	RNASE6	RNASE3	CLU	SEMG1	LYZ	PRSS3	PDZD11	CD4	ATP7A	RNASE8	RNASE7	PGLYRP4	DEFB1	PGLYRP3	DEFA1B	PGLYRP2	CHGA	HTN1	PGLYRP1	HTN3	S100A7	DEFA6	DEFA4	SLC11A1	DEFA5	DEFA3	DEFA1	S100A9	S100A8	BPIFA1	BPIFA2	PRSS2	GNLY	DEFB103A	DEFB103B	REG3A	ART1	REG3G	PRTN3	DEFB104B	DEFB104A	
FGFR2C LIGAND BINDING AND ACTIVATION%REACTOME DATABASE ID RELEASE 74%190375	FGFR2c ligand binding and activation	FGF4	FGF16	FGF6	FGF9	FGF18	FGF20	FGF1	FGF23	FGF2	
MATURATION OF REPLICASE PROTEINS%REACTOME DATABASE ID RELEASE 74%9694301	Maturation of replicase proteins	
DEFECTIVE ALG12 CAUSES ALG12-CDG (CDG-1G)%REACTOME%R-HSA-4720489.1	Defective ALG12 causes ALG12-CDG (CDG-1g)	ALG12	
REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA%REACTOME DATABASE ID RELEASE 74%3134975	Regulation of innate immune responses to cytosolic DNA	RPS27A	ZBP1	TBK1	IRF3	NLRP4	TRIM56	DTX4	TRIM21	UBA52	TMEM173	TRIM32	UBB	TREX1	UBC	DDX41	
MITOCHONDRIAL PROTEIN IMPORT%REACTOME DATABASE ID RELEASE 74%1268020	Mitochondrial protein import	TIMM9	TIMM13	TIMM10	TIMM8B	NDUFB8	TIMM8A	GFER	TOMM70A	TOMM7	TOMM5	TOMM6	VDAC1	OTC	IDH3G	ATP5A1	CS	ATP5G1	HSPD1	ACO2	SLC25A4	SLC25A6	ATP5B	SAMM50	CHCHD3	TOMM20	TOMM22	HSPA9	CHCHD4	CHCHD5	MTX1	CHCHD2	CHCHD7	MTX2	CMC4	CMC2	PAM16	BCS1L	COX17	TIMM50	PITRM1	GRPEL1	PMPCB	LDHD	GRPEL2	PMPCA	COA4	DNAJC19	COX19	CHCHD10	TIMM44	TIMM10B	COQ2	CYC1	HSCB	TIMM17A	TIMM17B	COA6	TIMM23	TIMM22	TIMM21	TAZ	SLC25A12	FXN	SLC25A13	TOMM40	
RETROGRADE NEUROTROPHIN SIGNALLING%REACTOME%R-HSA-177504.1	Retrograde neurotrophin signalling	AP2A2	NGF	DNM1	DNM2	AP2M1	DNM3	CLTC	CLTA	AP2B1	SH3GL2	NTRK1	AP2A1	DNAL4	AP2S1	
KINESINS%REACTOME%R-HSA-983189.3	Kinesins	KIF23	KIF26A	KIF22	KIF26B	KIF6	KIF16B	KIF27	KIF20A	KIF20B	KIF9	KIFC2	KIF2A	KIFC1	KLC1	KIF2C	KLC4	KLC3	KIF2B	KLC2	KIF3B	RACGAP1	KIF3C	KIF18A	KIF18B	KIF4B	KIF4A	KIF3A	KIF11	KIF15	KIF5B	KIF19	KIF5A	KIF13B	KIF21A	KIF21B	KIF1C	KIFAP3	KIF1B	KIF1A	KIF25	CENPE	
FRUCTOSE METABOLISM%REACTOME%R-HSA-5652084.6	Fructose metabolism	ALDH1A1	ALDOB	SORD	KHK	TKFC	GLYCTK	AKR1B1	
TRANSCRIPTIONAL REGULATION BY MECP2%REACTOME%R-HSA-8986944.2	Transcriptional Regulation by MECP2	LBR	CREB1	CAMK2G	DGCR8	BDNF	PTEN	TNRC6C	MOV10	AGO3	AGO4	AGO1	AGO2	GRIA2	AURKB	TNRC6A	TNRC6B	GRIN2A	GAD1	GAMT	GAD2	TBL1X	CAMK4	SST	PTPN4	TRPC3	SIN3A	HTT	PPARG	HDAC2	HDAC1	HDAC3	FOXG1	SLC2A3	TBL1XR1	OPRM1	SOX2	OPRK1	FKBP5	PTPN1	NCOR2	NCOR1	GPS2	MEF2C	GPRIN1	SGK1	PVALB	CRH	HIPK2	PRKACA	RBFOX1	CAMK2A	IRAK1	DLL1	MOBP	GRIN2B	MET	CAMK2B	CAMK2D	
PRE-NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM%REACTOME%R-HSA-1912399.2	Pre-NOTCH Processing in the Endoplasmic Reticulum	NOTCH3	NOTCH4	POGLUT1	POFUT1	NOTCH2	NOTCH1	
RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER%REACTOME%R-HSA-76061.2	RNA Polymerase III Transcription Initiation From Type 1 Promoter	GTF3C1	GTF3C2	GTF3C3	CRCP	GTF3C4	GTF3C5	GTF3C6	POLR2E	POLR2F	TBP	BRF1	POLR2H	POLR3GL	GTF3A	POLR3A	POLR3B	POLR2K	POLR2L	POLR3C	POLR3D	POLR3E	POLR1C	POLR3F	POLR3G	POLR3H	BDP1	POLR3K	
NEGATIVE REGULATION OF FGFR2 SIGNALING%REACTOME DATABASE ID RELEASE 74%5654727	Negative regulation of FGFR2 signaling	MAPK3	PTPN11	FGF20	UBA52	FGF23	FGF22	CBL	FGF16	MKNK1	UBB	FGF18	SPRY2	UBC	FGF10	RPS27A	PPP2CA	PPP2CB	MAPK1	PPP2R1A	FRS2	FGF1	FGF2	FGF3	FGF4	FGF6	FGF7	FGF9	BRAF	
PYRIMIDINE SALVAGE%REACTOME DATABASE ID RELEASE 74%73614	Pyrimidine salvage	CDA	UCKL1	UCK2	UCK1	TK2	DCK	TK1	TYMP	UPP2	HDHD1	UPP1	
DEFECTIVE SLC26A3 CAUSES CONGENITAL SECRETORY CHLORIDE DIARRHEA 1 (DIAR1)%REACTOME DATABASE ID RELEASE 74%5619085	Defective SLC26A3 causes congenital secretory chloride diarrhea 1 (DIAR1)	SLC26A3	
IRS-RELATED EVENTS TRIGGERED BY IGF1R%REACTOME%R-HSA-2428928.1	IRS-related events triggered by IGF1R	IRS1	PTPN11	FGF20	FGF23	GAB2	FGF22	GAB1	FGF16	IGF1R	NRAS	PDPK1	SOS1	HRAS	FGF19	PIK3R2	FGF18	PIK3R1	FGFR4	PIK3CA	AKT2	TLR9	FGF10	FLT3	PDE3B	THEM4	TRIB3	KLB	FLT3LG	FRS2	IRS2	FGF1	PIK3CB	FGF2	IGF2	FGF3	IGF1	IRS4	PIK3R4	FGF4	FGF6	FGF7	FGF9	PIK3C3	
ENOS ACTIVATION%REACTOME DATABASE ID RELEASE 74%203615	eNOS activation	DDAH1	DDAH2	AKT1	HSP90AA1	CYGB	SPR	CAV1	LYPLA1	ZDHHC21	NOS3	
DEFECTIVE CUBN CAUSES HEREDITARY MEGALOBLASTIC ANEMIA 1%REACTOME DATABASE ID RELEASE 74%3359463	Defective CUBN causes hereditary megaloblastic anemia 1	GIF	CUBN	AMN	
ASSEMBLY OF THE PRE-REPLICATIVE COMPLEX%REACTOME%R-HSA-68867.4	Assembly of the pre-replicative complex	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	MCM7	PSME3	MCM8	PSME4	PSME1	PSME2	PSMD10	PSMB11	UBA52	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	MCM3	MCM4	PSMA7	MCM5	PSMA8	PSMB6	MCM6	PSMB7	PSMB4	UBB	MCM2	PSMB5	PSMB2	PSMB3	UBC	PSMB1	E2F2	PSMF1	SHFM1	ORC5	PSMB8	ORC4	RPS27A	PSMB9	ORC6	ORC1	PSMC5	ORC3	PSMC6	ORC2	PSMC3	CDT1	PSMC4	PSMC1	CDC6	PSMC2	E2F3	GMNN	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD5	PSMD2	PSMD3	PSMD1	E2F1	PSMA5	
REPRODUCTION%REACTOME DATABASE ID RELEASE 74%1474165	Reproduction	STAG1	LMNB1	STAG2	HIST2H2AC	H2AFJ	H2AFZ	H2AFX	H2AFV	SMC1A	HIST2H2BE	HIST4H4	HIST1H2BN	HIST1H2BM	HIST1H2BO	PRDM9	HIST1H2BJ	SPO11	HIST1H2BI	BRCA1	HIST1H2BL	BRCA2	NBN	TOP3A	HIST1H2BK	TEX15	MSH4	HIST2H4A	DMC1	MSH5	HIST2H4B	BLM	PSMC3IP	RBBP8	RPA1	RPA2	CDK2	MRE11A	HIST3H3	MND1	MLH1	MLH3	RAD50	RAD51C	RAD51	RPA3	CATSPER1	CATSPER3	CATSPER2	B4GALT1	CATSPER4	HVCN1	ADAM21	ADAM20	IZUMO3	OVGP1	IZUMO2	IZUMO4	IZUMO1	ADAM30	ACR	ADAM2	ATR	KCNU1	CATSPERB	CATSPERD	CATSPERG	CD9	ZP1	ZP3	ZP2	SPAM1	ZP4	ATM	FKBP6	UBE2I	HIST1H2AE	HIST1H2AD	HIST3H2BB	HIST1H2AC	HIST1H2AB	HIST1H2AJ	SYCP2	SYCP1	TINF2	SYNE2	SYNE1	TERF1	SUN2	TERF2	SUN1	TEX12	POT1	HIST2H3A	SMC1B	TERF2IP	HIST1H2BF	SYCE3	ACD	HIST1H2BE	SYCE2	HIST1H2BH	SYCE1	HIST1H2BG	REC8	HIST2H3D	STAG3	HIST1H2BB	SYCP3	HIST2H3C	HIST1H2BA	HIST1H2BD	HIST1H2BC	HSPA2	H2AFB1	HIST1H3J	HIST1H3A	HIST1H3F	HIST1H3G	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	H3F3B	HIST1H4K	CDK4	HIST1H4L	H3F3A	SMC3	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	RAD21	HIST2H2AA4	
TWIK-RELEATED ACID-SENSITIVE K+ CHANNEL (TASK)%REACTOME DATABASE ID RELEASE 74%1299316	TWIK-releated acid-sensitive K+ channel (TASK)	KCNK9	KCNK3	
IGF1R SIGNALING CASCADE%REACTOME%R-HSA-2428924.1	IGF1R signaling cascade	IRS1	PTPN11	FGF20	FGF23	GAB2	FGF22	GAB1	FGF16	IGF1R	NRAS	PDPK1	SOS1	HRAS	FGF19	PIK3R2	FGF18	PIK3R1	FGFR4	PIK3CA	AKT2	TLR9	FGF10	FLT3	PDE3B	THEM4	TRIB3	KLB	FLT3LG	FRS2	IRS2	FGF1	PIK3CB	FGF2	IGF2	FGF3	IGF1	IRS4	PIK3R4	FGF4	FGF6	FGF7	FGF9	PIK3C3	
RHO GTPASES ACTIVATE ROCKS%REACTOME%R-HSA-5627117.3	RHO GTPases Activate ROCKs	PPP1CB	PPP1R12B	ROCK1	ROCK2	LIMK2	LIMK1	RHOC	RHOA	MYL12B	RHOB	MYL6	MYH9	MYH14	MYH11	PPP1R12A	CFL1	MYH10	MYL9	PAK1	
DEFECTIVE SLC5A7 CAUSES DISTAL HEREDITARY MOTOR NEURONOPATHY 7A (HMN7A)%REACTOME%R-HSA-5658471.1	Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)	SLC5A7	
SIGNALING BY NTRKS%REACTOME%R-HSA-166520.4	Signaling by NTRKs	RALA	RALB	ASCL1	KIDINS220	FOS	CREB1	RIT1	RIT2	DNM1	FOSB	DUSP4	DNM2	CDK5R2	DNM3	DUSP6	CDK5	DUSP7	MAPK13	DOCK3	MAPK7	PPP2CA	SRF	PPP2CB	NGF	NTF4	MAPK1	RAC1	IRS2	PIK3CB	CDK5R1	CRKL	RAPGEF1	MAP2K1	MAP2K2	SHC2	SHC3	MEF2D	NAB1	NAB2	RAP1A	RHOA	TCF12	CRK	NTRK2	SGK1	ADCYAP1	ADCYAP1R1	PPP2R5D	STAT3	RPS6KA3	RPS6KA2	RPS6KA1	MAPK3	BDNF	PTPN11	MAPK12	SHC1	GAB1	YWHAB	NRAS	PLCG1	SOS1	HRAS	MAPKAPK2	AP2A1	PCSK6	AP2A2	PCSK5	AP2M1	EGR2	CLTC	CLTA	MAPK14	MAPK11	PPP2R1B	FURIN	AP2S1	PTPRS	IRS1	SRC	NTRK3	PTPRO	NTF3	BAX	NELFB	AP2B1	SH3GL2	NTRK1	PIK3R2	ADORA2A	ATF1	PIK3R1	CHD4	ATF2	PIK3CA	REST	ELK1	MEF2A	TIAM1	MEF2C	VRK3	PPP2R1A	MAPKAPK3	FRS2	FRS3	SH3GL3	ARC	TRIB1	TPH1	RRAD	MAP2K5	F3	JUNB	EGR1	RALGDS	JUND	EGR3	EGR4	BRAF	FOSL1	GRIN2B	ID2	EP300	ID1	ID4	ID3	DNAL4	RPS6KA5	LYL1	DUSP3	VGF	
BILE ACID AND BILE SALT METABOLISM%REACTOME DATABASE ID RELEASE 74%194068	Bile acid and bile salt metabolism	RXRA	OSBP	SLCO1B1	SLCO1B3	SLC27A2	ACOT8	FABP6	ALB	AKR1C1	HSD17B4	AKR1C4	SLCO1A2	CYP46A1	SLC27A5	CYP39A1	OSBPL9	CYP27A1	OSBPL7	OSBPL6	ABCB11	OSBPL3	OSBPL2	AMACR	ABCC3	PTGIS	CYP7B1	SLC10A1	BAAT	CYP7A1	SLC10A2	NCOA1	ACOX2	NCOA2	NR1H4	AKR1C3	STARD5	CYP8B1	CH25H	HSD3B7	AKR1D1	AKR1C2	OSBPL1A	
DEFECTIVE SLC9A6 CAUSES X-LINKED, SYNDROMIC MENTAL RETARDATION,, CHRISTIANSON TYPE (MRXSCH)%REACTOME DATABASE ID RELEASE 74%5619092	Defective SLC9A6 causes X-linked, syndromic mental retardation,, Christianson type (MRXSCH)	SLC9A6	
HIV TRANSCRIPTION ELONGATION%REACTOME%R-HSA-167169.2	HIV Transcription Elongation	NELFB	CTDP1	CCNH	ELL	CCNT1	SUPT4H1	POLR2A	TCEB3	POLR2B	TCEB2	POLR2C	TCEB1	NELFA	POLR2D	NELFCD	NCBP1	TCEB3C	NCBP2	POLR2E	TCEB3CL	POLR2F	TCEB3B	NELFE	GTF2F1	POLR2G	SUPT16H	GTF2F2	POLR2H	SSRP1	POLR2I	SUPT5H	POLR2J	CDK9	TCEA1	POLR2K	TCEB3CL2	POLR2L	GTF2H1	GTF2H2	GTF2H3	GTF2H4	GTF2H5	CDK7	ERCC3	ERCC2	MNAT1	
CELL CYCLE, MITOTIC%REACTOME DATABASE ID RELEASE 74%69278	Cell Cycle, Mitotic	CSNK1E	DYNLL1	TUBG1	CKAP5	TUBA4A	HAUS2	PPME1	PHLDA1	HAUS1	AKAP9	LCMT1	CEP63	CDK11A	MAPRE1	AJUBA	SFI1	UBA52	OPTN	PAFAH1B1	SDCCAG8	DYNC1I2	DCTN2	SSNA1	DCTN3	CUL1	AURKA	CCNB2	CCNB1	UBB	HAUS8	HAUS7	PRKAR2B	UBC	CEP70	CEP72	CEP192	RPS27A	PCNT	CEP76	CLASP1	CEP78	PLK4	DYNC1H1	ODF2	CEP152	NDE1	RPA1	PLK1	RPA2	TUBB4B	TUBB4A	NEDD1	CENPJ	CDK1	PTK6	FGFR1OP	CEP41	RPA3	JAK2	TUBB8P12	TUBB8	TUBA3E	TUBA1C	TUBB6	TUBA1B	TUBB3	TUBB1	ANKLE2	PPP2R2A	SIRT2	TUBB2B	TUBB2A	TPX2	BUB1B	CDC20	BUB3	MAD2L1	CLASP2	RPS27	RCC1	XPO1	TNPO1	FBXL7	CSNK2A1	CSNK2A2	CSNK2B	RBX1	ERCC6L	ZWILCH	CASC5	SMC3	KNTC1	MAD1L1	CDCA5	CDCA8	EML4	PDS5B	TUBGCP2	EP300	PDS5A	NCAPG	VPS4A	PMF1	SKA1	NCAPH	SKA2	TUBGCP5	TUBGCP6	DSN1	RAD21	TUBGCP3	TUBGCP4	RCC2	NDC80	TUBG2	MZT2B	ZWINT	MZT2A	STAG1	STAG2	NME7	MZT1	AHCTF1	NCAPD2	SGOL2	CHMP2B	SGOL1	NUF2	CHMP2A	WAPAL	CHMP4C	SPDL1	CHMP4B	NDEL1	NUDC	CHMP3	RANGAP1	CHMP4A	SMC1A	FBXL18	CHMP6	INCENP	CHMP7	BIRC5	ITGB3BP	MIS12	CENPA	AURKB	NSL1	CENPC	BUB1	CENPT	CENPU	CENPF	APITD1	CENPH	CENPI	TAOK1	CENPK	CENPL	CENPM	CENPN	CENPO	B9D2	CENPP	CENPQ	SPC24	SPC25	LPIN1	LPIN2	PPP1CC	LPIN3	PTTG1	ESCO1	ESCO2	CCND2	RFC5	RFC3	FEN1	PCNA	RFC4	RFC1	PPP2R5E	LIG1	RFC2	PPP2R5B	PPP2R5A	POLE4	PPP2R5D	POLD3	PPP2R5C	POLD4	POLE2	POLD1	POLE3	POLD2	POLE	CDKN1A	CDKN1B	CDC25A	CDC25C	RBL2	RBL1	E2F4	GTSE1	FKBPL	KPNB1	RAN	RB1	NUP107	NUP188	SMC4	SMC2	GOLGA2	PPP2R1B	HIST1H2AE	HIST1H2AD	BANF1	HIST3H2BB	HIST1H2AC	HIST1H2AB	RAB2A	NUP214	NUP210	PRKCB	HIST1H2AJ	VRK1	PRKCA	LEMD3	LEMD2	NUP93	CTDNEP1	HIST2H3A	HIST1H2BF	HIST1H2BE	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	HIST1H2BA	BLZF1	HIST1H2BD	HIST1H2BC	NUP205	POM121	CCNH	H2AFB1	SET	DHFR	HIST1H3J	AAAS	ARPP19	NUP160	HIST1H3A	NUP85	RBBP4	TPR	HIST1H3F	HIST1H3G	NUP88	HIST1H3H	HIST1H3I	HIST1H3B	HIST1H3C	HIST1H3D	HIST1H3E	NEK9	NUP155	H3F3B	HMMR	HIST1H4K	HIST1H4L	NEK6	NCAPH2	NEK7	H3F3A	CDK7	NUP153	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	MNAT1	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	SETD8	DYNC1LI1	NUMA1	NCAPG2	DYNC1LI2	LMNB1	HIST2H2AC	MCM7	H2AFJ	MCM8	ZW10	NUP62	ENSA	UBE2D1	EMD	CDC23	KIF20A	NDC1	CDC26	CDC27	SEC13	SKP2	NUP133	ANAPC7	H2AFZ	UBE2E1	H2AFX	H2AFV	CCNA2	MASTL	CCNA1	HIST2H2BE	CCNE2	CCNE1	GORASP2	MCM3	HIST4H4	MCM4	NUP50	ANAPC4	CNEP1R1	MCM5	GORASP1	ANAPC5	NUP54	MCM6	MCPH1	TUBA4B	ANAPC1	HIST1H2BN	MCM2	HIST1H2BM	ANAPC2	RAB1A	ANAPC15	HIST1H2BO	ANAPC16	HIST1H2BJ	ANAPC10	HIST1H2BI	ANAPC11	HIST1H2BL	ORC5	RAB1B	USO1	ORC4	TUBAL3	FZR1	HIST1H2BK	ORC6	PPP2CA	KIF18A	ORC1	HIST2H4A	ORC3	PPP2CB	ORC2	HIST2H4B	CDT1	MAPK1	UBE2C	NUP43	CDC6	RAE1	RANBP2	UBE2S	CDC16	PPP2R2D	CDK2	TUBA8	HIST3H3	NUP35	NCAPD3	CLIP1	NUPL2	NUP37	KIF23	DYNLL2	KIF2A	KIF2C	KIF2B	HSP90AB1	PSMD8	PSMD9	CDC45	PSMD6	GINS1	PSMD7	GINS2	PSMD4	GINS3	PSMD5	DYNC1I1	GINS4	PSMD2	PSMD3	PSMD1	E2F1	PSMA5	CENPE	PSMA6	PSMA3	PSMA4	PSMA1	PSMA2	PSME3	PSME4	PSME1	PSME2	PSMD10	PSMB11	PSMD12	PSMD11	TOP2A	PSMD14	LIN54	NIPBL	PSMD13	LIN37	MAU2	MAX	PSMB10	LIN9	PSMA7	MYBL2	E2F5	LYN	LIN52	PSMA8	PSMB6	DYRK1A	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	E2F2	PSMF1	SHFM1	PSMB8	E2F6	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	IST1	SPAST	CC2D1B	SUMO1	UBE2I	E2F3	FOXM1	PKMYT1	CKS1B	CCND3	AKT2	AKT3	AKT1	GSK3B	CCND1	CDK4	RRM2	TP53	TYMS	CDC7	ABL1	CDC25B	CDKN2D	CDKN2B	CDKN2C	MYC	TK1	HDAC1	PRIM2	PRIM1	CABLES1	POLA1	POLA2	WEE1	DNA2	CDC14A	FBXO5	GMNN	MCM10	DBF4	RPA4	CDK6	CDKN2A	LBR	TFDP1	TFDP2	PPP2R3B	ESPL1	CDKN1C	CEP57	YWHAE	CETN2	CEP164	CCP110	PPP1CB	ACTR1A	PCM1	TUBA1A	PPP2R1A	CNTRL	CEP250	NEK2	PRKACA	BTRC	NINL	CEP290	YWHAG	RAB8A	CDK5RAP2	SKP1	OFD1	HSP90AA1	BORA	PPP1R12A	CEP135	FBXW11	TUBB	CEP131	HAUS4	HAUS3	CSNK1D	HAUS6	HAUS5	
FORMATION OF THE TERNARY COMPLEX, AND SUBSEQUENTLY, THE 43S COMPLEX%REACTOME%R-HSA-72695.2	Formation of the ternary complex, and subsequently, the 43S complex	RPS26	RPS25	RPS28	RPS27	RPS29	RPS20	RPS21	RPS24	RPS23	RPS4X	RPS3A	RPS27L	RPS15A	EIF2S2	RPS3	EIF2S1	RPS27A	EIF2S3	RPS2	EIF3M	EIF3K	EIF3L	EIF3I	EIF3J	EIF3G	EIF3H	EIF3E	EIF3F	FAU	EIF3C	EIF3D	EIF3A	EIF3B	RPS15	RPS14	RPS17	RPS16	RPS19	RPS18	RPS11	RPS10	RPS13	RPS12	RPS9	RPS7	EIF1AX	RPS8	RPS5	RPS6	RPSA	RPS4Y2	RPS4Y1	
REVERSAL OF ALKYLATION DAMAGE BY DNA DIOXYGENASES%REACTOME DATABASE ID RELEASE 74%73943	Reversal of alkylation damage by DNA dioxygenases	ALKBH3	FTO	ALKBH2	ALKBH5	ASCC1	ASCC2	ASCC3	
RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER%REACTOME DATABASE ID RELEASE 74%76071	RNA Polymerase III Transcription Initiation From Type 3 Promoter	CRCP	SNAPC5	SNAPC1	SNAPC2	SNAPC3	SNAPC4	ZNF143	POU2F1	POLR2E	BRF2	POLR2F	TBP	POLR2H	POLR3GL	POLR3A	POLR3B	POLR2K	POLR2L	POLR3C	POLR3D	POLR3E	POLR1C	POLR3F	POLR3G	POLR3H	BDP1	POLR3K	
TICAM1, RIP1-MEDIATED IKK COMPLEX RECRUITMENT%REACTOME DATABASE ID RELEASE 74%168927	TICAM1, RIP1-mediated IKK complex recruitment	RIPK3	RPS27A	UBE2D2	TICAM1	UBE2D1	RIPK1	TRAF6	UBA52	UBE2V1	IKBKB	BIRC2	TLR3	BIRC3	UBE2N	UBB	UBE2D3	UBC	IKBKG	CHUK	
TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL%REACTOME%R-HSA-6782315.5	tRNA modification in the nucleus and cytosol	THG1L	FTSJ1	TP53RK	THADA	WDR4	QTRT1	EPRS	LAGE3	TYW5	TYW3	TRMT5	TYW1	TPRKB	TRIT1	TRMT12	LCMT2	TRMT61A	TRMT44	METTL1	OSGEP	TRMT13	TRMT11	TRMT112	DUS2	CTU2	CTU1	PUS3	CDKAL1	PUS7	ALKBH8	TRDMT1	QTRTD1	KIAA1456	NSUN2	NSUN6	URM1	TRMT10A	ADAT1	TRMT1	ADAT2	TRMT6	
RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS%REACTOME%R-HSA-8939246.1	RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	PRKCB	CBFB	CREBBP	CSF2	LGALS3	RUNX1	
DEFECTIVE MPI CAUSES MPI-CDG (CDG-1B)%REACTOME%R-HSA-4043916.1	Defective MPI causes MPI-CDG (CDG-1b)	MPI	
SIGNALING BY FGFR4%REACTOME DATABASE ID RELEASE 74%5654743	Signaling by FGFR4	MAPK3	PTPN11	FGF20	UBA52	FGF23	GAB1	CBL	FGF16	NRAS	PLCG1	SOS1	MKNK1	HRAS	FGF19	UBB	FGF18	SPRY2	PIK3R1	FGFR4	PIK3CA	UBC	RPS27A	PPP2CA	PPP2CB	MAPK1	PPP2R1A	KLB	FRS2	FRS3	FGF1	FGF2	FGF4	FGF6	FGF9	BRAF	
SIGNALING BY FGFR3 POINT MUTANTS IN CANCER%REACTOME%R-HSA-8853338.2	Signaling by FGFR3 point mutants in cancer	FRS2	FGF20	FGF1	FGF23	FGF2	GAB1	FGF4	FGFR3	FGF16	NRAS	FGF9	PLCG1	SOS1	HRAS	FGF18	PIK3R1	PIK3CA	
INTERLEUKIN-2 FAMILY SIGNALING%REACTOME DATABASE ID RELEASE 74%451927	Interleukin-2 family signaling	IL2RG	CSF2RB	IL9R	JAK3	JAK1	CSF2RA	PTK2B	IL2RA	IL2RB	GAB2	SHC1	IL21	IL21R	IL2	STAT4	IL3	PTPN6	IL5	SOS1	PIK3R3	LGALS9	PIK3R2	IL15RA	PIK3R1	SYK	PIK3CA	LCK	INPP5D	GRB2	IL15	CSF2	STAT5A	STAT5B	PIK3CD	IL5RA	PIK3CB	STAT1	HAVCR2	STAT3	JAK2	SOS2	INPPL1	IL3RA	IL9	
DEFECTIVE GALK1 CAN CAUSE GALACTOSEMIA II (GALCT2)%REACTOME%R-HSA-5609976.2	Defective GALK1 can cause Galactosemia II (GALCT2)	GALK1	
GAB1 SIGNALOSOME%REACTOME%R-HSA-180292.3	GAB1 signalosome	PXN	AREG	CSK	SRC	EPGN	PTPN11	EREG	BTC	EGF	GAB1	TGFA	EGFR	PIK3R1	PIK3CA	PAG1	HBEGF	
G BETA:GAMMA SIGNALLING THROUGH PLC BETA%REACTOME%R-HSA-418217.3	G beta:gamma signalling through PLC beta	GNGT1	GNGT2	GNG12	GNG11	GNG13	PLCB3	PLCB1	PLCB2	GNB2	GNB1	GNG3	GNB4	GNG10	GNB3	GNG2	GNB5	GNG5	GNG4	GNG7	GNG8	
FANCONI ANEMIA PATHWAY%REACTOME DATABASE ID RELEASE 74%6783310	Fanconi Anemia Pathway	FANCC	ATR	UBA52	MUS81	EME1	STRA13	EME2	WDR48	UBB	SLX1B	SLX1A	APITD1	UBC	SLX4	RPS27A	RPA1	USP1	FAAP100	RPA2	FAAP24	FAAP20	DCLRE1B	DCLRE1A	FANCM	FANCL	FANCA	RPA3	FANCB	FANCE	FANCG	FANCF	FANCD2	FAN1	POLN	ATRIP	FANCI	ERCC4	UBE2T	ERCC1	
ATTACHMENT OF GPI ANCHOR TO UPAR%REACTOME%R-HSA-162791.2	Attachment of GPI anchor to uPAR	PIGT	PIGK	PLAUR	GPAA1	PIGS	PIGU	PGAP1	
SIGNALING BY MAP2K MUTANTS%REACTOME DATABASE ID RELEASE 74%9652169	Signaling by MAP2K mutants	MAPK3	MAPK1	MAP2K1	MAP2K2	
NUCLEOTIDE EXCISION REPAIR%REACTOME%R-HSA-5696398.2	Nucleotide Excision Repair	POLK	XRCC1	LIG3	UBA52	UBB	ELL	UBC	ACTL6A	RPS27A	XPC	HMGN1	AQR	USP45	ZNF830	RAD23A	UVSSA	ERCC8	TCEA1	RPA1	RPA2	RPA3	PRPF19	ERCC4	ERCC1	YY1	XAB2	UBE2V2	XPA	PARP2	CHD1L	CUL4A	DDB1	POLR2A	POLR2B	ERCC5	POLR2C	CUL4B	PPIE	POLR2D	DDB2	POLR2E	POLR2F	POLR2G	POLR2H	RFC5	POLR2I	RFC3	POLR2J	PCNA	POLR2K	RFC4	POLR2L	RFC1	LIG1	RFC2	ISY1	POLE4	POLD3	USP7	POLD4	POLE2	POLD1	POLE3	POLD2	POLE	RUVBL1	NFRKB	INO80C	INO80B	INO80E	INO80D	INO80	COPS7B	ACTR5	COPS7A	ACTR8	SUMO3	SUMO2	UBE2N	TFPT	PIAS3	MCRS1	RAD23B	PARP1	SUMO1	ACTB	UBE2I	GPS1	PIAS1	CCNH	CETN2	RBX1	GTF2H1	COPS4	GTF2H2	COPS3	GTF2H3	COPS6	GTF2H4	COPS5	GTF2H5	CDK7	COPS2	ERCC3	RNF111	COPS8	ERCC2	ERCC6	EP300	MNAT1	
AUTOPHAGY%REACTOME DATABASE ID RELEASE 74%9612973	Autophagy	SQSTM1	VPS37C	DYNC1LI1	VPS37D	DYNLL1	VPS37A	DYNC1LI2	VPS37B	CHMP2B	CHMP2A	CHMP4C	CFTR	CHMP4B	VCP	UBAP1	UBA52	CHMP3	CHMP4A	CHMP6	CHMP7	TOMM70A	DYNC1I2	TOMM7	VPS28	TOMM5	TOMM6	UBB	VDAC1	UBC	RPS27A	PCNT	ULK1	HBB	DYNC1H1	GFAP	CETN1	PARK7	PARK2	MFN1	MFN2	MAP1LC3B	DYNLL2	PRKAA1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	PLIN3	RPTOR	ATM	SLC38A9	PRKAB2	ATG7	TSC2	TSC1	ATG5	PRKAB1	MTMR14	RRAGA	RRAGC	RRAGB	RHEB	RRAGD	LAMTOR2	MTMR3	LAMTOR1	LAMTOR4	LAMTOR3	HSP90AB1	LAMTOR5	PLIN2	DYNC1I1	PIK3C3	WIPI1	MAP1LC3A	FUNDC1	USP30	PEX5	MTERF3	NBR1	GABARAPL2	UBE2V1	LAMP2	GABARAP	UBE2N	EPAS1	PINK1	EEF1A1	ATG3	GABARAPL1	HSPA8	ATG9B	ATG9A	ATG10	ATG14	ATG13	ATG101	ATG16L1	WDR45	MAP1LC3C	RB1CC1	WIPI2	ATG4C	ATG4B	ATG4A	ATG4D	TOMM20	WDR45B	AMBRA1	TOMM22	CSNK2A1	CSNK2A2	HDAC6	CSNK2B	HSF1	UVRAG	MTOR	BECN1	MLST8	IFT88	ARL13B	ATG12	PIK3R4	HSP90AA1	TSG101	MVB12B	RNASE1	MVB12A	TOMM40	
NTF4 ACTIVATES NTRK2 (TRKB) SIGNALING%REACTOME DATABASE ID RELEASE 74%9026357	NTF4 activates NTRK2 (TRKB) signaling	NTF4	NTRK2	
FUSION OF THE INFLUENZA VIRION TO THE HOST CELL ENDOSOME%REACTOME%R-HSA-168288.3	Fusion of the Influenza Virion to the Host Cell Endosome	
EVASION OF OXIDATIVE STRESS INDUCED SENESCENCE DUE TO DEFECTIVE P16INK4A BINDING TO CDK4 AND CDK6%REACTOME%R-HSA-9632700.2	Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	CDK6	CDKN2A	CDK4	
SIGNALING BY NOTCH1 HD+PEST DOMAIN MUTANTS IN CANCER%REACTOME%R-HSA-2894858.1	Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	MIB2	MIB1	CCNC	NCSTN	NEURL1	MAML3	MAMLD1	HDAC4	UBA52	HDAC5	NOTCH1	HDAC8	HDAC9	HDAC7	CDK8	HEY1	HEY2	CUL1	UBB	UBC	HDAC10	HDAC11	RPS27A	TBL1X	MYC	SNW1	HDAC2	HDAC1	HDAC3	TBL1XR1	HDAC6	NCOR2	NCOR1	RBX1	MAML2	MAML1	KAT2B	SKP1	PSEN2	RBPJ	ADAM10	KAT2A	DLL1	HEYL	DLL4	ADAM17	APH1A	NEURL1B	APH1B	CREBBP	EP300	HES1	HES5	JAG2	PSENEN	PSEN1	JAG1	
IRAK4 DEFICIENCY (TLR2 4)%REACTOME%R-HSA-5603041.1	IRAK4 deficiency (TLR2 4)	LY96	TLR6	IRAK4	MYD88	TIRAP	TLR2	TLR1	CD14	TLR4	BTK	CD36	
ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING%REACTOME DATABASE ID RELEASE 74%451326	Activation of kainate receptors upon glutamate binding	GNG12	GNG11	GNG13	GNB2	GNB1	GNB4	GNB3	GNB5	GNGT1	GNGT2	DLG1	DLG3	PLCB3	DLG4	GRIK5	PLCB1	GRIK3	PLCB2	GRIK4	GRIK1	GRIK2	NCALD	GNG3	GNG10	GNG2	GNG5	GNG4	GNG7	GNG8	
ESTROGEN-STIMULATED SIGNALING THROUGH PRKCZ%REACTOME%R-HSA-9634635.2	Estrogen-stimulated signaling through PRKCZ	NRAS	PDPK1	MAPK1	HRAS	PRKCZ	
FASL  CD95L SIGNALING%REACTOME DATABASE ID RELEASE 74%75157	FasL  CD95L signaling	FASLG	CASP8	FAS	CASP10	FADD	
TNF RECEPTOR SUPERFAMILY (TNFSF) MEMBERS MEDIATING NON-CANONICAL NF-KB PATHWAY%REACTOME DATABASE ID RELEASE 74%5676594	TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	TNFSF14	TNFSF12	TRAF2	MAP3K14	TRAF3	TNFRSF13C	TNFSF13B	TNFRSF12A	LTA	LTB	BIRC2	CD40LG	LTBR	BIRC3	TNFSF11	TNFRSF11A	
RHO GTPASES ACTIVATE KTN1%REACTOME%R-HSA-5625970.1	RHO GTPases activate KTN1	KIF5B	KIF5A	KLC1	KTN1	KLC4	KLC3	KLC2	RHOG	CDC42	RAC1	RHOA	
TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT%REACTOME%R-HSA-159231.2	Transport of Mature mRNA Derived from an Intronless Transcript	NUP214	NUP210	NUP62	NUP93	NDC1	SEC13	NUP133	NUP50	NUP205	NUP54	POM121	CPSF1	CPSF3	AAAS	CPSF2	NUP160	WDR33	NUP85	NCBP1	FIP1L1	TPR	NCBP2	NUP88	SYMPK	EIF4E	CPSF4	NUP43	RAE1	RANBP2	NUP155	NUP35	NUPL2	NUP37	NUP107	NUP153	NUP188	NXF1	
SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS%REACTOME DATABASE ID RELEASE 74%3108214	SUMOylation of DNA damage response and repair proteins	HERC2	PHC2	STAG1	STAG2	PHC1	NUP62	RNF168	NDC1	SEC13	NUP133	SMC5	SMC6	PHC3	SMC1A	HDAC7	NUP50	SUMO3	SUMO2	NUP54	PIAS4	RING1	BRCA1	NDNL2	XPC	BLM	NUP43	RAE1	RANBP2	RPA1	XRCC4	NUP35	PARP1	NUPL2	NUP37	NUP107	SUMO1	NUP188	UBE2I	CBX8	WRN	CBX4	CBX2	RAD52	MDC1	NUP214	NUP210	SP100	NUP93	BMI1	PIAS1	NUP205	POM121	AAAS	NUP160	EID3	NUP85	CETN2	TPR	PML	NUP88	CDKN2A	TDG	PCGF2	NUP155	NSMCE4A	RNF2	NSMCE2	NSMCE1	NUP153	SMC3	RAD21	
SIGNALING BY WNT%REACTOME%R-HSA-195721.5	Signaling by WNT	CSNK1E	HIST2H2AC	H2AFJ	UBA52	H2AFZ	H2AFX	H2AFV	HIST2H2BE	HIST4H4	CUL1	UBB	HIST1H2BN	HIST1H2BM	HIST1H2BO	UBC	HIST1H2BJ	HIST1H2BI	HIST1H2BL	RPS27A	HIST1H2BK	PPP2CA	HIST2H4A	PPP2CB	HIST2H4B	HIST3H3	MEN1	PIP5K1B	USP8	CDC73	SCRIB	WNT2B	PRICKLE1	VANGL2	KMT2D	LEO1	WNT9B	WNT9A	WNT16	WLS	PSMD8	WNT8A	WNT8B	PSMD9	PSMD6	VPS29	PSMD7	PSMD4	VPS35	PSMD5	TMED5	WNT6	PSMD2	PSMD3	AMER1	WNT1	PSMD1	WNT2	AXIN1	VPS26A	WNT3	APC	MAP3K7	WNT4	FZD1	WNT10B	PSMA5	WNT10A	PSMA6	PSMA3	WNT3A	FZD7	PSMA4	PSMA1	WNT7B	DAAM1	PSMA2	PSME3	PSME4	PSME1	FZD8	PSME2	WNT7A	PSMD10	PSMB11	PSMD12	PSMD11	PSMD14	PSMD13	PSMB10	PSMA7	XPO1	PSMA8	PSMB6	TERT	PSMB7	PSMB4	PSMB5	YWHAZ	PSMB2	PSMB3	PSMB1	PSMF1	SHFM1	PSMB8	PSMB9	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMC2	SMARCA4	PARD6A	CSNK2A1	CSNK2A2	CSNK2B	RAC2	AKT2	TLE4	TLE2	GNGT1	TLE1	PPP3CA	AKT1	PPP3CB	RBX1	GNGT2	GNAT2	CAV1	PRKG2	PRKG1	WNT5A	PLCB3	PLCB1	PLCB2	GSK3B	CAMK2A	LEF1	TCF7	ITPR1	ITPR2	ITPR3	NLK	GNG3	GNG10	RNF146	PPP3R1	GNG2	WNT11	GNG5	GNG4	CREBBP	GNG7	EP300	GNG8	PDE6B	PDE6A	CTBP1	TCF7L2	FZD3	CHD8	CBY1	TCF7L1	SOX3	FZD2	SOX17	FZD5	SRY	PDE6G	SOX6	FZD4	SOX7	FZD6	SOX4	NFATC1	GNG12	CSNK1A1	BCL9L	GNG11	TLE3	GNG13	CTNNBIP1	SOX13	GNAO1	PYGO1	TNRC6C	MOV10	PYGO2	AGO3	BCL9	AGO4	GNB2	AGO1	PRKCG	GNB1	AGO2	GNB4	GNB3	RSPO3	CTNNB1	GNB5	TNRC6A	TNRC6B	MYC	TNKS2	TNKS	RAC1	HDAC1	XIAP	CUL3	WNT5B	ROR1	ROR2	RHOA	CLTB	ASH2L	SMURF2	SMURF1	CSNK1G2	ARRB2	PPP2R5E	PPP2R5B	PPP2R5A	PPP2R5D	PPP2R5C	SNX3	RUVBL1	AP2A1	AP2A2	PORCN	SOX9	RUNX3	AP2M1	CLTC	TRRAP	CLTA	FRAT1	FRAT2	DKK1	DKK2	DKK4	SFRP1	SFRP2	HECW1	CCDC88C	RSPO2	RSPO1	PPP2R1B	RSPO4	KREMEN1	HIST1H2AE	KREMEN2	HIST1H2AD	WIF1	HIST3H2BB	LGR6	LGR5	HIST1H2AC	LGR4	HIST1H2AB	AP2S1	RNF43	KLHL12	USP34	PRKCB	SOST	HIST1H2AJ	DACT1	AXIN2	RBBP5	PRKCA	LRP5	LRP6	ZNRF3	HIST2H3A	ZRANB1	HIST1H2BF	HIST1H2BE	KAT5	AP2B1	HIST1H2BH	HIST1H2BG	HIST2H3D	HIST1H2BB	HIST2H3C	CTBP2	HIST1H2BA	DVL1	SOX2	AES	DVL2	HIST1H2BD	HIST1H2BC	DVL3	H2AFB1	HIST1H3J	HIST1H3A	HIST1H3F	HIST1H3G	PFN1	HIST1H3H	HIST1H3I	HIST1H3B	PPP2R1A	HIST1H3C	RAC3	HIST1H3D	HIST1H3E	BTRC	H3F3B	HIST1H4K	HIST1H4L	SKP1	H3F3A	H2BFS	HIST1H4A	HIST1H4B	HIST1H4H	HIST1H4I	HIST1H4J	HIST1H4C	HIST1H4D	HIST1H4E	HIST1H4F	HIST2H2AA3	HIST2H2AA4	
NEGATIVE REGULATION OF NMDA RECEPTOR-MEDIATED NEURONAL TRANSMISSION%REACTOME DATABASE ID RELEASE 74%9617324	Negative regulation of NMDA receptor-mediated neuronal transmission	CAMK4	CAMK1	GRIN1	NEFL	CAMK2G	DLG1	DLG3	ACTN2	DLG4	CAMK2A	DLG2	PPM1E	PPM1F	GRIN2B	GRIN2A	GRIN2D	LRRC7	CAMK2B	GRIN2C	CAMK2D	
RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS%REACTOME%R-HSA-8935964.1	RUNX1 regulates expression of components of tight junctions	TJP1	CLDN5	CBFB	OCLN	RUNX1	
DEFECTIVE GFPT1 CAUSES CMSTA1%REACTOME%R-HSA-4085023.1	Defective GFPT1 causes CMSTA1	GFPT1	
