Package: seq.hotSPOT
Type: Package
Title: Targeted sequencing panel design based on mutation hotspots
Version: 1.12.0
Authors@R: c(
  person("Sydney", "Grant", email = "sydney.grant@roswellpark.org", role = c("aut", "cre")),
  person("Lei", "Wei", email = "lei.wei@roswellpark.org", role = c("aut")),
  person("Gyorgy", "Paragh", email = "gyorgy.paragh@roswellpark.org", role = c("aut")))
Description: seq.hotSPOT provides a resource for designing effective sequencing panels to 
    help improve mutation capture efficacy for ultradeep sequencing projects. Using SNV datasets, this package designs custom
    panels for any tissue of interest and identify the genomic regions likely to contain the most mutations. Establishing efficient
    targeted sequencing panels can allow researchers to study mutation burden in tissues at high depth without the 
    economic burden of whole-exome or whole-genome sequencing. This tool was developed to make high-depth sequencing panels
    to study low-frequency clonal mutations in clinically normal and cancerous tissues.
License: Artistic-2.0
Encoding: UTF-8
LazyData: FALSE
RoxygenNote: 7.2.3
biocViews: Software, Technology, Sequencing, DNASeq, WholeGenome
Imports: R.utils, hash, stats, base, utils
Suggests: BiocStyle, knitr, rmarkdown, testthat (>= 3.0.0)
VignetteBuilder: knitr
URL: https://github.com/sydney-grant/seq.hotSPOT
BugReports: https://github.com/sydney-grant/seq.hotSPOT/issues
Config/testthat/edition: 3
git_url: https://git.bioconductor.org/packages/seq.hotSPOT
git_branch: RELEASE_3_23
git_last_commit: b774b03
git_last_commit_date: 2026-04-28
Repository: Bioconductor 3.23
Date/Publication: 2026-04-28
NeedsCompilation: no
Packaged: 2026-04-28 23:29:51 UTC; biocbuild
Author: Sydney Grant [aut, cre],
  Lei Wei [aut],
  Gyorgy Paragh [aut]
Maintainer: Sydney Grant <sydney.grant@roswellpark.org>
Depends: R (>= 3.5.0)
Built: R 4.6.0; ; 2026-04-29 05:00:39 UTC; unix
