Package: TCC
Type: Package
Title: TCC: Differential expression analysis for tag count data with
        robust normalization strategies
Version: 1.52.0
Author: Jianqiang Sun, Tomoaki Nishiyama, Kentaro Shimizu, and Koji
        Kadota
Maintainer: Jianqiang Sun <sun@bitdessin.dev>, Tomoaki Nishiyama
 <tomoakin@staff.kanazawa-u.ac.jp>
Description: This package provides a series of functions for performing
        differential expression analysis from RNA-seq count data using
        robust normalization strategy (called DEGES). The basic idea of
        DEGES is that potential differentially expressed genes or
        transcripts (DEGs) among compared samples should be removed
        before data normalization to obtain a well-ranked gene list
        where true DEGs are top-ranked and non-DEGs are bottom ranked.
        This can be done by performing a multi-step normalization
        strategy (called DEGES for DEG elimination strategy). A major
        characteristic of TCC is to provide the robust normalization
        methods for several kinds of count data (two-group with or
        without replicates, multi-group/multi-factor, and so on) by
        virtue of the use of combinations of functions in depended
        packages.
Depends: R (>= 3.0), methods, DESeq2, edgeR, ROC
Suggests: RUnit, BiocGenerics
License: GPL-2
Copyright: Authors listed above
biocViews: ImmunoOncology, Sequencing, DifferentialExpression, RNASeq
Config/pak/sysreqs: zlib1g-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2026-04-28 12:38:07 UTC
RemoteUrl: https://github.com/bioc/TCC
RemoteRef: RELEASE_3_23
RemoteSha: 6c302b88a3f15dc51f6fe4860637f07d7d2d1832
NeedsCompilation: no
Packaged: 2026-04-30 06:57:36 UTC; root
Built: R 4.6.0; ; 2026-04-30 07:02:25 UTC; windows
