# On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs

## Documentation for package ‘crisprScore’ version 1.16.0

- DESCRIPTION file
- User guides, package vignettes and other documentation
- Package NEWS
- Package README

## Help Pages

getCasRxRFScores | Calculate on-target sgRNA activity scores for CasRx using CasRx-RF
getCFDScores | Calculate CFD off-target specificity scores
getCRISPRaterScores | Calculate on-target sgRNA activity scores for Cas9 using CRISPRater
getCRISPRscanScores | Calculate on-target sgRNA activity scores for Cas9 using CRISPRscan
getDeepHFScores | Calculate on-target sgRNA activity scores for Cas9 using DeepHF
getEnPAMGBScores | Calculate on-target sgRNA activity scores for enCas12a using enPAM+GB
getLindelScores | Predict frameshift ratios from CRISPR/Cas9 indel prediction using Lindel
getMITScores | Calculate MIT off-target specificity scores for CRISPR/Cas9
getRuleSet1Scores | Calculate on-target sgRNA activity scores for Cas9 using Rule Set 1
getRuleSet3Scores | Calculate on-target sgRNA activity scores for SpCas9 using Rule Set 3
scoringMethodsInfo | data.frame detailing available scoring methods