Mutational Signature Estimation for Single Samples
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Documentation for package ‘SigsPack’ version 1.23.0
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| bootstrap_mut_catalogues | Bootstraps a given mutational catalogue |
| cosmicSigs | COSMIC Signature Profiles |
| create_mut_catalogues | Creates simulated mutational catalogues |
| decomposeQP | decomposeQP function |
| get_context_freq | Extract occurence of tri-nucleotide contexts |
| hg19context_freq | Trinuecleotide frequencies of the human reference genome hg19 |
| normalize | Normalize mutational catalogues |
| plot_bootstrapped_exposure | Plot signature exposure estimation for several samples |
| signature_exposure | Estimates the signature exposure of a mutational catalogue |
| sigProfiler20190522 | COSMIC v3 whole genome SBS Signature Profiles |
| sigProfilerExome | COSMIC v3 exome SBS Signature Profiles |
| summarize_exposures | Signature exposure analysis of a mutational catalogue |
| vcf2mut_cat | Derive the mutational catalogue from a vcf |