Bayesian Modeling of Barcoded Tumor Mixtures for Quantitative Treatment Resistance Analysis


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Documentation for package ‘barmixR’ version 0.99.2

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barmixRQTR Fit the barmixR model for quantitative treatment resistance (QTR)
barmixR_fit Class barmixR_fit
fractionRatio Compute ratios of relative barcode abundance between treatments
populationRatio Compute ratios of population size between treatments
ppcBarcodes Posterior predictive checks for barcode composition
ppcPopulation Posterior predictive checks for population size
QTRDecision Rank treatments within each cell line using QTR boxplot summaries
QTRheatmap Visualize quantitative treatment resistance (QTR) using bubble heatmaps
QTRresistance Estimate quantitative treatment resistance (QTR)