Package: escape
Title: Easy single-cell analysis platform for enrichment
Version: 2.9.1
Authors@R: c(
    person(given = "Nick", family = "Borcherding", role = c("aut", "cre"), email = "ncborch@gmail.com"),
    person(given = "Jared", family = "Andrews", role = c("aut"), email = "jared.andrews07@gmail.com"),
    person(given = "Tobias", family = "Hoch", role = c("ctb"), email = "tobias@hoch.earth"),
    person(given = "Alexei", family = "Martsinkovskiy", role = c("ctb"), email = "alexei.martsinkovskiy@gmail.com"),
    person(given = "Cathal", family = "King", role = c("ctb"))
    )
Description: A bridging R package to facilitate gene set enrichment analysis (GSEA) in the context of single-cell RNA sequencing. Using raw count information, Seurat objects, SingleCellExperiment or SpatialExperiment format, users can perform and visualize ssGSEA, GSVA, AUCell, and UCell-based enrichment calculations across individual cells. An optional plaid backend provides fast reimplementations of these methods plus PLAID, singscore, and scSE scoring. Alternatively, escape supports use of rank-based GSEA, such as the use of differential gene expression via fgsea.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: false
biocViews: Software, SingleCell, Classification, Annotation,
        GeneSetEnrichment, Sequencing, GeneSignaling, Pathways
Depends: R (>= 4.1)
Imports: ggdist, ggplot2 (>= 3.5.0), grDevices, Matrix, MatrixGenerics,
        methods, stats, SummarizedExperiment, utils
Suggests: AUCell, BiocParallel, BiocStyle, DelayedMatrixStats, dplyr,
        fgsea, GSEABase, ggraph, ggridges, ggpointdensity, GSVA,
        hexbin, igraph, irlba, knitr, msigdb, patchwork, plaid,
        rmarkdown, rlang, S4Vectors, scran, SeuratObject, Seurat,
        SingleCellExperiment, SpatialExperiment, spelling, stringr,
        testthat (>= 3.0.0), UCell
VignetteBuilder: knitr
Language: en-US
BugReports: https://github.com/BorchLab/escape/issues
Config/roxygen2/version: 8.0.0
git_url: https://git.bioconductor.org/packages/escape
git_branch: devel
git_last_commit: da55640
git_last_commit_date: 2026-08-09
Repository: Bioconductor 3.24
Date/Publication: 2026-10-27
NeedsCompilation: no
Packaged: 2026-10-27 21:42:17 UTC; biocbuild
Author: Nick Borcherding [aut, cre],
  Jared Andrews [aut],
  Tobias Hoch [ctb],
  Alexei Martsinkovskiy [ctb],
  Cathal King [ctb]
Maintainer: Nick Borcherding <ncborch@gmail.com>
