Package: awst
Title: Asymmetric Within-Sample Transformation
Version: 1.20.0
Authors@R: 
    c(person(given = "Davide",
                family = "Risso",
                role = c("aut", "cre", "cph"),
                email = "risso.davide@gmail.com",
                comment = c(ORCID = "0000-0001-8508-5012")),
        person(given = "Stefano",
               family = "Pagnotta",
               role = c("aut", "cph"),
               email = "smpagnotta@gmail.com",
               comment = c(ORCID = "0000-0002-8298-9777")))
Description: We propose an Asymmetric Within-Sample Transformation
        (AWST) to regularize RNA-seq read counts and reduce the effect
        of noise on the classification of samples. AWST comprises two
        main steps: standardization and smoothing. These steps
        transform gene expression data to reduce the noise of the lowly
        expressed features, which suffer from background effects and
        low signal-to-noise ratio, and the influence of the highly
        expressed features, which may be the result of amplification
        bias and other experimental artifacts.
License: MIT + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.1.1
URL: https://github.com/drisso/awst
BugReports: https://github.com/drisso/awst/issues
Imports: stats, methods, SummarizedExperiment
Suggests: airway, ggplot2, testthat, EDASeq, knitr, BiocStyle,
        RefManageR, sessioninfo, rmarkdown
biocViews: Normalization, GeneExpression, RNASeq, Software,
        Transcriptomics, Sequencing, SingleCell
VignetteBuilder: knitr
Config/pak/sysreqs: zlib1g-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2026-04-28 12:55:53 UTC
RemoteUrl: https://github.com/bioc/awst
RemoteRef: RELEASE_3_23
RemoteSha: ca56bf2b0aba474d165cfa1512081b954399d006
NeedsCompilation: no
Packaged: 2026-04-29 18:10:59 UTC; root
Author: Davide Risso [aut, cre, cph] (ORCID:
    <https://orcid.org/0000-0001-8508-5012>),
  Stefano Pagnotta [aut, cph] (ORCID:
    <https://orcid.org/0000-0002-8298-9777>)
Maintainer: Davide Risso <risso.davide@gmail.com>
Built: R 4.6.0; ; 2026-04-29 19:06:31 UTC; unix
