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DAssemble

This is the development version of DAssemble; to use it, please install the devel version of Bioconductor.

Ensemble Models for Differential Analysis


Bioconductor version: Development (3.24)

The DAssemble package implements an ensemble framework for differential-abundance and differential-expression analysis across bulk RNA-seq, single-cell RNA-seq, and microbiome studies. It wraps a collection of popular DA/DE methods as core methods and combines them via Cauchy Combination Tests (CCT), optionally augmented by simple enhancers such as Wilcoxon, Kolmogorov–Smirnov, and presence–absence logistic regression.

Author: Himel Mallick [aut], Ziyu Liu [aut], Nalin Arora [aut, cre] ORCID iD ORCID: 0009-0009-1340-688X

Maintainer: Nalin Arora <naa4050 at med.cornell.edu>

Citation (from within R, enter citation("DAssemble")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("DAssemble")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DAssemble")
DAssemble: Ensemble Differential Analysis HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews DifferentialExpression, Microbiome, Normalization, RNASeq, Regression, SingleCell, Software, StatisticalMethod
Version 0.99.3
In Bioconductor since BioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.6.0)
Imports stats, utils, dplyr, MultiAssayExperiment, SummarizedExperiment
System Requirements
URL https://github.com/himelmallick/DAssemble
Bug Reports https://github.com/himelmallick/DAssemble/issues
See More
Suggests DESeq2, edgeR, limma, dearseq, metagenomeSeq, MAST, cplm, dfadjust, glmmTMB, logging, MASS, pbapply, preprocessCore, Maaslin2, maaslin3, LOCOM2, MicrobiomeStat, ANCOMBC, ALDEx2, parallel, airway, scran, SingleCellExperiment, knitr, rmarkdown, BiocStyle, phyloseq, Seurat, S4Vectors, testthat (>= 3.0.0), TreeSummarizedExperiment, KernSmooth, foreign, nnet, rpart, spatial, boot, class
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DAssemble_0.99.3.tar.gz
Windows Binary (x86_64) DAssemble_0.99.3.zip
macOS Binary (big-sur-x86_64) DAssemble_0.99.3.tgz
macOS Binary (sonoma-arm64) DAssemble_0.99.3.tgz
Source Repository git clone https://git.bioconductor.org/packages/DAssemble
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DAssemble
Bioc Package Browser https://code.bioconductor.org/browse/DAssemble/
Package Short Url https://bioconductor.org/packages/DAssemble/
Package Downloads Report Download Stats