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RBPSpecificity

This is the development version of RBPSpecificity; to use it, please install the devel version of Bioconductor.

RBP Inherent Specificity and Variation Sensitivity Analysis Tool


Bioconductor version: Development (3.24)

Provides tools to analyze RNA Binding Protein (RBP) binding specificities from high-throughput sequencing data. Functions include calculating K-mer enrichment, Inherent Specificity (IS), and Mutational Sensitivity (VS), along with visualization of IS and VS. For detailed methodology and applications, please refer to our manuscript (see URL field or vignette).

Author: Soon Yi [aut, cre] ORCID iD ORCID: 0000-0002-4535-6532 , National Institutes of Health [fnd] (T32 GM152319)

Maintainer: Soon Yi <cu.soonyi at gmail.com>

Citation (from within R, enter citation("RBPSpecificity")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("RBPSpecificity")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RBPSpecificity")
Introduction to RBPSpecificity HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Coverage, GeneRegulation, GenomeAnnotation, KEGG, MotifAnnotation, Sequencing, Software, Visualization
Version 0.99.6
In Bioconductor since BioC 3.24 (R-4.6)
License GPL-3
Depends R (>= 4.6.0)
Imports Biostrings, BSgenome, GenomeInfoDb, GenomicRanges, ggplot2, methods, reshape2, S4Vectors, stats, utils
System Requirements
URL https://www.biorxiv.org/content/10.1101/2025.03.28.646018v2 https://github.com/S00NYI/RBPSpecificity https://github.com/S00NYI/BITS_Specificity
Bug Reports https://github.com/S00NYI/RBPSpecificity/issues
See More
Suggests BiocStyle, BSgenome.Hsapiens.UCSC.hg38, IRanges, knitr, rmarkdown, testthat
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package RBPSpecificity_0.99.6.tar.gz
Windows Binary (x86_64) RBPSpecificity_0.99.6.zip
macOS Binary (big-sur-x86_64) RBPSpecificity_0.99.6.tgz
macOS Binary (sonoma-arm64) RBPSpecificity_0.99.6.tgz
Source Repository git clone https://git.bioconductor.org/packages/RBPSpecificity
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/RBPSpecificity
Bioc Package Browser https://code.bioconductor.org/browse/RBPSpecificity/
Package Short Url https://bioconductor.org/packages/RBPSpecificity/
Package Downloads Report Download Stats